LOCUS       NZ_CP023865            28043 bp    DNA     circular CON 27-APR-2024
DEFINITION  Actinoplanes teichomyceticus ATCC 31121 chromosome, complete genome.
ACCESSION   NZ_CP023865
VERSION     NZ_CP023865.1
KEYWORDS    RefSeq.
SOURCE      Actinoplanes teichomyceticus ATCC 31121
  ORGANISM  Actinoplanes teichomyceticus ATCC 31121
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Actinoplanes.
REFERENCE   1  (bases 1 to 8287152)
  AUTHORS   Yushchuk,O., Horbal,L., Fedorenko,V., Ostash,B., Luzhetskyy,A.,
            Kalinowski,J. and Ruckert,C.
  TITLE     Complete genome sequence of Actinoplanes teichomyceticus ATCC 31121,
            type strain of Actinoplanes teichomyceticus and producer of
            teicoplanin, isolated from soil near Nimodi, India
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8287152)
  AUTHORS   Yushchuk,O., Horbal,L., Fedorenko,V., Ostash,B., Luzhetskyy,A.,
            Kalinowski,J. and Ruckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2017) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.5
            Genome Coverage                   :: 184.1x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003711105.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 03:18:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,294
            CDSs (total)                      :: 7,220
            Genes (coding)                    :: 7,116
            CDSs (with protein)               :: 7,116
            Genes (RNA)                       :: 74
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 27 of 104
            Pseudo Genes (incomplete)         :: 92 of 104
            Pseudo Genes (internal stop)      :: 11 of 104
            Pseudo Genes (multiple problems)  :: 22 of 104
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:55:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2815967
            Orig. end                         :: 2844010
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28043
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azoxy-crosslink"
                     /region_number="7"
                     /rules="(azdH and LPG_synthase_C and azdO and vlmB)"
                     /tool="antismash"
     cand_cluster    1..28043
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(azdH and LPG_synthase_C and azdO and
                     vlmB)"
                     /kind="single"
                     /product="azoxy-crosslink"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28043
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:18043]"
                     /cutoff="20000"
                     /detection_rule="(azdH and LPG_synthase_C and azdO and
                     vlmB)"
                     /neighbourhood="10000"
                     /product="azoxy-crosslink"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18043
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(azdH and LPG_synthase_C and azdO and
                     vlmB)"
                     /neighbourhood="10000"
                     /product="azoxy-crosslink"
                     /protocluster_number="1"
     misc_feature    complement(1036..1054)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.9"
                     /tool="antismash"
     gene            complement(1093..2247)
                     /gene="trpB"
                     /locus_tag="ACTEI_RS12635"
     CDS             complement(1093..2247)
                     /EC_number="4.2.1.20"
                     /GO_function="GO:0004834 - tryptophan synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0000162 - tryptophan biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="trpB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510550.1"
                     /locus_tag="ACTEI_RS12635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptophan synthase subunit beta"
                     /protein_id="WP_122977833.1"
                     /sec_met_domain="PALP (E-value: 8.6e-53, bitscore: 178.4,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLMSAPTATGRFGQFGGRYVPESLIPACAALDVAFRDAWSDPAF
                     RDRLARLRADYAGRPTALTPAENLSAQLGITLLLKREDLAHTGSHKINNVLGQALLARR
                     MGKTRLIAETGAGQHGVATATAAALFGMRATVYMGERDIARQQLNVFRMELLGAEVIPV
                     TSGSRTLKDATNEAMRAWVAAVDEAHFCLGSVAGPHPYPWLVRELQRVIGEEARAQAPS
                     VPDVVVACVGGGSNAAGTFAGFVDTPARLVGVEAAGGAAMTDGTPGVVHGYRSFVLQDP
                     DGQVLEAESIAAGLDYPGIGPEHAHLGASGRAEYRTVTDEEVITAVRRLARSEGIICAL
                     ESAHAVAWVLRAAGTPDLPTGSTVLLTLSGRGDKDMATLAGEGR"
     misc_feature    2310..2323
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.06"
                     /tool="antismash"
     gene            complement(2333..3487)
                     /locus_tag="ACTEI_RS12640"
     CDS             complement(2333..3487)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014689987.1"
                     /locus_tag="ACTEI_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_122982104.1"
                     /transl_table=11
                     /translation="MSVWKSRPALRWLVPGATAIVVIGGGAAAGTIVASAEPSLPERSA
                     AQLLVDLQNAKPAGLSGTVVQSADLGLPGVAGLASSLGASAGGGLTNLVSGSNTARVWY
                     AGEDKVRLALQSAQGETDVIRNGSDLWQWSSSANTGMHLKLPADTTAKPHSLPSAVPST
                     PQEAADAALAAITPSTKVQTTGAAQVAGRDAYELVLSPKDTESLVGQLRLAIDAEEHIP
                     LRVEVYAKNAVKPAVRIAFDTISFQVPDAEQFTFNPPPGAKIDEVGSKAVKPSDATEKS
                     TARPASKVPAGAEAAEPTVIGKGWTAIASGKIPADALDRLTGVGKGSGEKADQAKALLS
                     MVPEVSGSWGKGRLLSGSLFSVLITDDGRVFAGLVTPEALYKVA"
     misc_feature    complement(3481..3495)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.35"
                     /tool="antismash"
     gene            3645..4349
                     /locus_tag="ACTEI_RS12645"
     CDS             3645..4349
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510548.1"
                     /locus_tag="ACTEI_RS12645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_122977834.1"
                     /transl_table=11
                     /translation="MRLLVVEDEERLAAALRRGLQAEGFAVDVAHDGQDGLEMARHGGY
                     DAMILDVMLPRLSGYRVVRQLRAERHWLPVLMLSAKDGEYDQADGLDCGADDYLTKPFS
                     YVVLLARLRALLRRGIQARPVVLACGDVELDPAEKRVLVTGTEVTLTTREFALLEYLIR
                     RPGEVVSKTELLDHVWDAALDTAPNAVEVYVGYLRRKIGRERLETVRGAGYRLVPLSGM
                     PEKPGAPAESRP"
     gene            4642..6018
                     /locus_tag="ACTEI_RS12650"
     CDS             4642..6018
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014689985.1"
                     /locus_tag="ACTEI_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_122977835.1"
                     /transl_table=11
                     /translation="MRRRLRELSLRARLLLISAAALSFGLAAGGVLLVAVLTFAQGRAV
                     HAEALETAEGVARLVDQGQLTDPIQVTPGVQVQVIDEQNRVRAVSATADRLVPILYVKE
                     LRVLRDGEGVEIPGERIGFDGAARVVKVTAGPATHPLRILVARSTSQLTQSVHLLRVTL
                     LVAFPLLVALLAAGLWRALGAALRPVDALRAGAEEITGGTRAGRLPVPGSHDEIRRLAL
                     TLNDMLHRLDTARARQRAFVADAAHELRSPLTNMRTELEVAQRLPDDTDWPALADDLLT
                     DVQRLSRLVDDLLLLARSDDGAARAVSGRLEQVDLGQLVGEVAARYPGVRHDESAEPLP
                     LVAEPDALARVVANLLDNACRHRRSRVTVRTAASGAELLVVVTDDGPGIPAADRERVFD
                     RFTRLDDARARDAGGSGLGLAIVRELVRRHGGSVTLGDAEPGLRVEVRLPRAREVITSG
                     "
     gene            6124..6873
                     /locus_tag="ACTEI_RS12655"
     CDS             6124..6873
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014689984.1"
                     /locus_tag="ACTEI_RS12655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YcnI family protein"
                     /protein_id="WP_122977836.1"
                     /transl_table=11
                     /translation="MSLFKRSAVVAAAAGVLTLALAGPAAAHVTVNPNSATAGGYAKVS
                     FRVPNESDSASTTKLEVNLPADQPIASVSVKPVPGWTAVAQKTKLATPIKAHDTEITEA
                     VSKITWTAAKGSEIKPGEFQEFDVSMGALPESGQLVFKALQTYSNGDVVRWIDEPTTDG
                     SEPESPAPVLKIVPAANGSAAPSAAAAAPAAEADDSDDSDDSDGSGSGLGLAGLIAGLV
                     ALLLAGLAYLKASRKPESAAPGTPAAS"
     misc_feature    complement(7369..7383)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    7419..7439
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    7440..7456
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.0"
                     /tool="antismash"
     gene            7459..8226
                     /locus_tag="ACTEI_RS12660"
     CDS             7459..8226
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014689983.1"
                     /locus_tag="ACTEI_RS12660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Pr6Pr family membrane protein"
                     /protein_id="WP_170206133.1"
                     /transl_table=11
                     /translation="MNGSRVYARLWHGLLAAVVVCSLVTQIVLTAQGSPDSDGVVEPVV
                     TRFVRMLSYFTIQSNILLLIVAVTLAVNPERDGPLWRVIRLDAVLGIIITGLVYATVLA
                     GQANPTGAGWWSNLGFHYVAPWWALSGWLLFGPRSRMDRRTLGWAVVWPVLWIGYTFAH
                     GAVTDWYPYPFASVTDIGYGAAVRNMAFVVVIAILFGAILWGLDRRLPGGRPVASTPVR
                     NSQRAESVVSADPGPADGTGVGRSGVERQRQAC"
     gene            complement(8555..9838)
                     /gene="serS"
                     /locus_tag="ACTEI_RS12665"
     CDS             complement(8555..9838)
                     /EC_number="6.1.1.11"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004828 - serine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006434 - seryl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="serS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020511116.1"
                     /locus_tag="ACTEI_RS12665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine--tRNA ligase"
                     /protein_id="WP_122977837.1"
                     /transl_table=11
                     /translation="MIDLRLLREQPDLFRAGQRLRGESVSKVDDLLRADEERRVAVQRF
                     EALRTEQKLLGKRVAAASGDERAELLARTRQLAAEVKAAQAAADKAGEVLRQAHLALPN
                     LVVDGVPPGGEDDFVVLRTVGDPPGLTAPRDHLEIGEALGAIDTERGAKVSGSRFYFLT
                     GVGALLQLGLLQLAVAQAVEHGFTPSITPALVKPEAMQGTGFLGAHAGEVYRLEADDLY
                     LVGTSEVALAAYHRDEVLDLRGGPLRYAGWSSCFRREAGSHGRDVRGILRVHQFDKVEM
                     FSFCDPDDAAGEHLALLAMQEEMLAKVEVPYRVIDVAAGDLGSSAARKYDCEAWVPSQG
                     RYREVTSTSNCTTFQARRLDIRHRGRDGTLRTPATLNGTLATTRWLIPILENHQQPDGS
                     VRVPAALRPYLGGREVLEPVTGPAHRAA"
     gene            complement(9831..9989)
                     /locus_tag="ACTEI_RS36925"
     CDS             complement(9831..9989)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTEI_RS36925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_164465929.1"
                     /transl_table=11
                     /translation="MSDTTQDEVQAGLQAVLQSFVMVCGAPDDAAVCAQADDTLAKVDE
                     LLARAHD"
     gene            complement(10001..11005)
                     /locus_tag="ACTEI_RS12670"
     CDS             complement(10001..11005)
                     /NRPS_PKS="Domain: LPG_synthase_C (19-313). E-value: 6e-68.
                     Score: 220.9. Matches aSDomain:
                     nrpspksdomains_ACTEI_RS12670_LPG_synthase_C.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azoxy-crosslink: LPG_synthase_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018827970.1"
                     /locus_tag="ACTEI_RS12670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2156 domain-containing protein"
                     /protein_id="WP_122977838.1"
                     /sec_met_domain="LPG_synthase_C (E-value: 7.2e-66,
                     bitscore: 220.9, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDSPSPAEVALNCIRDYPGANNPSSFLAVNEGNEYFTLPGRPGV
                     VAYRTAGRYLVQFGGPFAPAESYADLLHGFLDFARAQQRTVVAVQLQRDDVDAYARSGF
                     TVNQIGASWAVDLARFTLAGTKFMQLRNKISRSFRAGLQVIEAKLDDWYDQMRELDAVW
                     LTSKGEHSRELEFLVGQYGGEAQQHRRLFVGTIEDRLVGYISYSPVYGDRPGWMHDLSR
                     RIPDRVPGIMEAINRTAIERFQSENVPWLHFGFTPFTGLAEENLPAGHSPGFHLLMQLL
                     WLHGEAVYPAQTQLAYKQKWDPHVCIPEYVAFQGRASIAGLAHIFRASNALEV"
     aSDomain        complement(10067..10948)
                     /aSDomain="LPG_synthase_C"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTEI_RS12670_LPG_synthase_C.1"
                     /evalue="6.00E-68"
                     /label="ACTEI_RS12670_LPG_synthase_C.1"
                     /locus_tag="ACTEI_RS12670"
                     /protein_end="313"
                     /protein_start="19"
                     /score="220.9"
                     /tool="antismash"
                     /translation="GANNPSSFLAVNEGNEYFTLPGRPGVVAYRTAGRYLVQFGGPFAP
                     AESYADLLHGFLDFARAQQRTVVAVQLQRDDVDAYARSGFTVNQIGASWAVDLARFTLA
                     GTKFMQLRNKISRSFRAGLQVIEAKLDDWYDQMRELDAVWLTSKGEHSRELEFLVGQYG
                     GEAQQHRRLFVGTIEDRLVGYISYSPVYGDRPGWMHDLSRRIPDRVPGIMEAINRTAIE
                     RFQSENVPWLHFGFTPFTGLAEENLPAGHSPGFHLLMQLLWLHGEAVYPAQTQLAYKQK
                     WDPHVCIPEYVAF"
     misc_feature    11005..11018
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     tRNA            11153..11241
                     /anticodon=(pos:2827157..2827159,aa:Gly,seq:tcc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="ACTEI_RS36930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Gly"
     gene            11153..11241
                     /locus_tag="ACTEI_RS36930"
     gene            11373..12989
                     /locus_tag="ACTEI_RS12675"
     CDS             11373..12989
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018252056.1"
                     /locus_tag="ACTEI_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_203723710.1"
                     /sec_met_domain="Aldedh (E-value: 3.8e-63, bitscore: 212.3,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRTAGRPEPLRSYGSYIADRDVDGAGWVYTVSARSLLEDVFTSV
                     SLKRALENDPDGEALQHPYVVGRCAVAGPADLDASLDAAAEAAPRWAAMPLETRMSLGE
                     RFRAALHENRETFLELLIAEAHPRKLAEWELAGLLQIYSPESLSFAASQMHTEFRHGDR
                     RLIVRRQADGVVCVNPPQNAPASSAALAVLALMAGNAVVVRAPRSIPLSTMWLMRDLVA
                     PLLRELGAPPGTLNVVCSKPRETLDRWLRHPGVDDIFYFGGSAEGLRFQAECVEHGKKP
                     ILELAGNDGVVVWHDADLQLAAEAITECFFGSGQICMVPNYVIAHPLIADELLERVAKA
                     AAEIRPGLPGEPDSLLSPVRRSEKFFALLEQARSRGAQLVCGGERIELDGTVSDTGVFL
                     QPTVLRVDGLAGARDVDAVRHETFFPLLPVVVPEPAADAELLDRVIQYVNSNEYGLRNS
                     LWAGSDEVVGRFVAEIRNGGLLKINDSHIGFLPYLPTHGGTGLTSGVYGEANYPIVKTS
                     HQQGVSISTGSNPRQAVFGLG"
     gene            13016..14155
                     /locus_tag="ACTEI_RS12680"
     CDS             13016..14155
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azoxy-crosslink: azdH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018827966.1"
                     /locus_tag="ACTEI_RS12680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_122977840.1"
                     /sec_met_domain="azdH (E-value: 4e-169, bitscore: 561.0,
                     seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSLDIAREACEASHPGLLKALSEHSLSELERPGGPAVKLFRDHG
                     GAGLLVPRDFGGAGAGALTAVRINRALGAASPSLGAAVTMHHFTAGMLYSLTGSAGRLT
                     GAQLGLLERVAGERLLMASAWAEGRSSQNILVPAVKAEPAPGGGFVVNGVKKPCSLARS
                     MDLLTASVAVPGDDGESLAVLLIPADTPGISVHPFWSNPVLAAAESEEVRLEDVHVPED
                     LVIRTVPDDPTRLDDLQSAGFVWFVMLISSVYTGAASALTERVLKAGRGSVTDRAALGV
                     QLDSAVGLLEGVARAVDAGELNEDVVAAALVARYAVQDHLVRVADLAVETLGGIAWIKD
                     PEIAYLASAVRPLAFHPPSRASAAEPLIDYFSGEPLRLS"
     gene            14181..15467
                     /locus_tag="ACTEI_RS12685"
     CDS             14181..15467
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (41-360). E-value: 1.2e-83.
                     Score: 272.8. Matches aSDomain:
                     nrpspksdomains_ACTEI_RS12685_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620386.1"
                     /locus_tag="ACTEI_RS12685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_122977841.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.8e-84, bitscore:
                     281.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTVASPASVDTEEEILNLYRAHLSKGRATLAELFGSHMEVASEG
                     AWIYTSDGEEFLNFGGYGVFVMGARHPRVLDAVTRQLRTHPTSTRILLEPTVARAAEAL
                     TRITPPGMDRVHFSLSGAEAVETALKLGRAHGRRRLVSMSGGYHGKTLGALSATAKEVY
                     QRPFRPLLPDVTHLPYGDADALGEHLSRYPGEVTVIVEPVQGEGGVVIPPAGYLKQVEQ
                     LCRRHGAFLIVDEVQTGMGRLGSWWGCTAADVVPDVLLTGKALGGGILPVSAAVADRAT
                     FKPFDKDPYLHTATFSGQPLLMAAVQGAIEAVEQDDLVARAAALGARLLPEIRAIVHRN
                     IPDLTVDVRGVGLLIGVELIEAGLAGELLIELFNHGVVANHSMIGSSVVRFTPPATLTE
                     RELTTFFQALDGATRDLVNRRTRMPKGGN"
     aSDomain        14304..15260
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTEI_RS12685_Aminotran_3.1"
                     /evalue="1.20E-83"
                     /label="ACTEI_RS12685_Aminotran_3.1"
                     /locus_tag="ACTEI_RS12685"
                     /protein_end="360"
                     /protein_start="41"
                     /score="272.8"
                     /tool="antismash"
                     /translation="ASEGAWIYTSDGEEFLNFGGYGVFVMGARHPRVLDAVTRQLRTHP
                     TSTRILLEPTVARAAEALTRITPPGMDRVHFSLSGAEAVETALKLGRAHGRRRLVSMSG
                     GYHGKTLGALSATAKEVYQRPFRPLLPDVTHLPYGDADALGEHLSRYPGEVTVIVEPVQ
                     GEGGVVIPPAGYLKQVEQLCRRHGAFLIVDEVQTGMGRLGSWWGCTAADVVPDVLLTGK
                     ALGGGILPVSAAVADRATFKPFDKDPYLHTATFSGQPLLMAAVQGAIEAVEQDDLVARA
                     AALGARLLPEIRAIVHRNIPDLTVDVRGVGLLIGVELI"
     gene            15470..15961
                     /locus_tag="ACTEI_RS12690"
     CDS             15470..15961
                     /NRPS_PKS="Domain: Polyketide_cyc (14-133). E-value: 3e-15.
                     Score: 48.6. Matches aSDomain:
                     nrpspksdomains_ACTEI_RS12690_Polyketide_cyc.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620387.1"
                     /locus_tag="ACTEI_RS12690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_122977842.1"
                     /transl_table=11
                     /translation="MRQVSLDAVIHNTAADYVLQQIARFDQYPTLAPHVNATTVHTGLP
                     EPVGSSSWELHFRSGLLRWTEQERFLTDQLRIEFAQTDGDFDEFSGVWQLRQDGADTAL
                     SFRCDFDFGIPSLEGILDPIAERVIRETAAWAVAGLFDHLEVTFAGPAPAVPVPAGDAG
                     "
     aSDomain        15512..15868
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTEI_RS12690_Polyketide_cyc.1"
                     /domain_subtypes="Polyketide_cyc"
                     /evalue="3.00E-15"
                     /label="ACTEI_RS12690_Polyketide_cyc.1"
                     /locus_tag="ACTEI_RS12690"
                     /protein_end="133"
                     /protein_start="14"
                     /score="48.6"
                     /tool="antismash"
                     /translation="ADYVLQQIARFDQYPTLAPHVNATTVHTGLPEPVGSSSWELHFRS
                     GLLRWTEQERFLTDQLRIEFAQTDGDFDEFSGVWQLRQDGADTALSFRCDFDFGIPSLE
                     GILDPIAERVIRETA"
     gene            15988..16518
                     /locus_tag="ACTEI_RS12695"
     CDS             15988..16518
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azoxy-crosslink: azdO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620388.1"
                     /locus_tag="ACTEI_RS12695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_122977843.1"
                     /sec_met_domain="azdO (E-value: 1.4e-69, bitscore: 231.7,
                     seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAKNPFETRATFRAHRAEYLVGFAASTVLLIWHYDEIRWLPAIG
                     LFLYIDLIGYIPGAIAFHRSRTKRISKVYYYLYNTMHSMITQAAVVVLWGLLIGWEWAL
                     LIIPFHLFGDRGVFGNFLKPLSLPFEPVAYPGYARLIDALRSGVDSSGSAAGVLGAEAP
                     ARVPDAAPAAAVR"
     gene            16518..17063
                     /locus_tag="ACTEI_RS12700"
     CDS             16518..17063
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013756.4"
                     /locus_tag="ACTEI_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavin reductase family protein"
                     /protein_id="WP_122977844.1"
                     /transl_table=11
                     /translation="MDTETLEGRRRRAVRHFASGVAVLTVVDDSGTPHGTTVSAVTAIS
                     REPLLLGVCLRLNSAFARRVRDGGRFTVNVLRSDQYATARWFADPARPAGTAQFRDVAW
                     ETDALTGAPTLTGSLATLGCQLVERLALGDHDLLVAQVLAGSASWGSPLLSYAGRLHDG
                     DLHSMAPDSSELTVRSSR"
     gene            17060..18043
                     /locus_tag="ACTEI_RS12705"
     CDS             17060..18043
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azoxy-crosslink: vlmB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620390.1"
                     /locus_tag="ACTEI_RS12705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VlmB-like protein"
                     /protein_id="WP_122977845.1"
                     /sec_met_domain="vlmB (E-value: 2.5e-167, bitscore: 554.5,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVIPPEADWEQAPGLLTGAKTLELSAERCNLGYWLSAVAQGTL
                     RDRAVTGHHNAAVPPFMKQDGPLREAMMLELGLRSVAEEKATRILSYYVANAPGIVEME
                     FYATQLIDEARHSKVFRDHLVELGVPAAELHDTIAEMSREYVPEVLQPVEDLAARIIRD
                     ERDFVGGVAVFTIVIEGVLAPAAELAERKWDRLDPAASEISRGAAIDEIRHLTVGSSII
                     RDHLIRHPEYRPRLMEILAAGRELWDRVPDRKYVMYREELFQKGMAQQADLLRDYEVWP
                     GRLLLDTTPEERYDMAERWTDEMAESRLRFMGLEDALPLLSGTDVA"
     gene            18040..19065
                     /locus_tag="ACTEI_RS12710"
     CDS             18040..19065
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620391.1"
                     /locus_tag="ACTEI_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_122977846.1"
                     /sec_met_domain="fabH (E-value: 9.3e-111, bitscore: 368.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAGGSGDRHPVLAGVGGWLPSRVVTNDDLAAHLDTSDAWIRSRT
                     GIGSRRFAEPGVSTGDLAVAAGALALKSSGEAQADAVVLATATPDHPLPGTAPQVAERL
                     GLIGAAAFDVAAVCAGFVYGLATAGGLIAAGTARRVLLIGAETFTSIVNPRDRSTAVIF
                     ADGAGAVVLRAGRPDEPGALGPTDLGSDGGNHELIMVPGGGSRQRSSGADPGPEDHFFH
                     MAGRDVYRHAVERLTSSSRAALAHAGWQVTDVDRFVPHQANAKISAAVADRLGLDADRV
                     LSNIAEVGNTSAASIPLLLAQAGADGRLQPGHRVLLAAFGGGLTWGASTLVWPDITALT
                     V"
     gene            19092..19322
                     /locus_tag="ACTEI_RS12715"
     CDS             19092..19322
                     /NRPS_PKS="Domain: PP-binding (3-68). E-value: 1.6e-16.
                     Score: 52.4. Matches aSDomain:
                     nrpspksdomains_ACTEI_RS12715_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620392.1"
                     /locus_tag="ACTEI_RS12715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_122977847.1"
                     /sec_met_domain="PP-binding (E-value: 1.7e-12, bitscore:
                     46.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFDTVKKVLVSRFQVPAEDIEPEASLEDLELDSLDLVELATILES
                     EYGVRITDDEIAEAKQVGAVADLAARKAATV"
     aSDomain        19101..19295
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTEI_RS12715_PP-binding.1"
                     /evalue="1.60E-16"
                     /label="ACTEI_RS12715_PP-binding.1"
                     /locus_tag="ACTEI_RS12715"
                     /protein_end="68"
                     /protein_start="3"
                     /score="52.4"
                     /tool="antismash"
                     /translation="TVKKVLVSRFQVPAEDIEPEASLEDLELDSLDLVELATILESEYG
                     VRITDDEIAEAKQVGAVADL"
     gene            19322..20539
                     /locus_tag="ACTEI_RS12720"
     CDS             19322..20539
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (62-403). E-value:
                     2.2e-64. Score: 209.8. Matches aSDomain:
                     nrpspksdomains_ACTEI_RS12720_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620393.1"
                     /locus_tag="ACTEI_RS12720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_122977848.1"
                     /sec_met_domain="t2fas (E-value: 6.3e-123, bitscore: 409.3,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.6e-52, bitscore:
                     177.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAHRVAVTGLGLVTPAGIGVTETWERILDAEPTAAHDPELADNP
                     VTISCRVPGFDGGALLGRRARKMDRFTQFAVVAATEALADAGLDPARWDGARVAVVLGN
                     ADGGFATVEQQHSVLTQQGAGFVSALLLPMQLSNMLAGQLSLQFGATGPSFCVATACAS
                     GTTAIGLACDLLRLDRCDVVITGGSEALVTPLIMAGFARMGALSRRAGDPREAMRPFEV
                     ERDGFVGAEGAGILVLERLADARARGAGIRATVDGTGHSADAHHLTAPDPEGRGLERAI
                     RAALADADAGAGDIDHVNAHGTATPLGDLAESRAVERVLRSRPLVSSTKGVTGHMLGAA
                     GAVEAALTVLAVQHGVVPPTANLDRQDPEVEVEVATKPVHRRLDAALSLSAGFGGQNAA
                     VLVRAI"
     aSDomain        19508..20530
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTEI_RS12720_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.20E-64"
                     /label="ACTEI_RS12720_PKS_KS.1"
                     /locus_tag="ACTEI_RS12720"
                     /protein_end="403"
                     /protein_start="62"
                     /score="209.8"
                     /tool="antismash"
                     /translation="RRARKMDRFTQFAVVAATEALADAGLDPARWDGARVAVVLGNADG
                     GFATVEQQHSVLTQQGAGFVSALLLPMQLSNMLAGQLSLQFGATGPSFCVATACASGTT
                     AIGLACDLLRLDRCDVVITGGSEALVTPLIMAGFARMGALSRRAGDPREAMRPFEVERD
                     GFVGAEGAGILVLERLADARARGAGIRATVDGTGHSADAHHLTAPDPEGRGLERAIRAA
                     LADADAGAGDIDHVNAHGTATPLGDLAESRAVERVLRSRPLVSSTKGVTGHMLGAAGAV
                     EAALTVLAVQHGVVPPTANLDRQDPEVEVEVATKPVHRRLDAALSLSAGFGGQNAAVLV
                     R"
     CDS_motif       19775..19822
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTEI_RS12720_0001"
                     /evalue="1.90E-03"
                     /label="PKSI-KS_m3"
                     /locus_tag="ACTEI_RS12720"
                     /protein_end="167"
                     /protein_start="151"
                     /score="10.9"
                     /tool="antismash"
                     /translation="GPSFCVATACASGTTA"
     CDS_motif       20213..20257
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ACTEI_RS12720_0002"
                     /evalue="1.50E-02"
                     /label="PKSI-KS_m5"
                     /locus_tag="ACTEI_RS12720"
                     /protein_end="312"
                     /protein_start="297"
                     /score="8.4"
                     /tool="antismash"
                     /translation="VNAHGTATPLGDLAE"
     gene            complement(20725..21531)
                     /locus_tag="ACTEI_RS12725"
     CDS             complement(20725..21531)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020678871.1"
                     /locus_tag="ACTEI_RS12725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_239082487.1"
                     /transl_table=11
                     /translation="MNAPVASRSTAGALVRQWRHRRRLSQLELANKAGISARHLSFIET
                     GRSVPSRDVLLQLADCLELSLRERNRLLLASGYAPAYLETPLDAPSITAVRAAVRQVVS
                     GHDPYPAVVVDRHWNIVDANVALTTLLGMAAPWLVTPPDANVLRASLHPEGLAPHILNF
                     AEWRSHVLARLHRQVLLSGDSVLAALEEELQGYPCDPGQPEPQPGASARIFVPLRLKSE
                     FGELAFFSTVATFGTPLDITVAELCIESFYPADEATATALRSITAR"
     misc_feature    21544..21557
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     misc_feature    21571..21588
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.17"
                     /tool="antismash"
     gene            complement(21608..22069)
                     /locus_tag="ACTEI_RS12730"
     CDS             complement(21608..22069)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620396.1"
                     /locus_tag="ACTEI_RS12730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MaoC/PaaZ C-terminal domain-containing protein"
                     /protein_id="WP_122977849.1"
                     /transl_table=11
                     /translation="MSARRTPVTGLPALVGEELGVSDWRDVSAATVTAFAEITGDRQWI
                     HVDAERAAAGPFGAPVAHGFLLMSMVPAMLSEVVDVIGADHVVNKGVSDVRLLSPVRVG
                     DRVRGRVRVARVRPRPRGFWETDYGVELAAEGSGTPALRMTLTLLYHVE"
     gene            complement(22066..22911)
                     /gene="fabI"
                     /locus_tag="ACTEI_RS12735"
     CDS             complement(22066..22911)
                     /EC_number="1.3.1.9"
                     /GO_function="GO:0004318 - enoyl-[acyl-carrier-protein]
                     reductase (NADH) activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fabI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018827415.1"
                     /locus_tag="ACTEI_RS12735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="WP_122977850.1"
                     /sec_met_domain="adh_short_C2 (E-value: 4.5e-67, bitscore:
                     225.3, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSSDLRKRWGTAVLLDGKKLLITGVITERSIAFAAARQAQLQGA
                     EVVLTGFGRGLRITEKIAARLPHRCDVLELDLTDAEHLTRVAAQVQERWGRLDGVLHAA
                     AFAPAEALDGGFLTAGWPEVARTMHVSTYSFAALGRATAPLLAAAGGGSIVGLDFDAGQ
                     VWPGYDWMGVAKGGLESCCRYLAHALGPQGTRVNLVAAGPLRTVAASAIGTFETLVEAW
                     RERAALGWDHTDPEPVGRAICALWSDWLPAVTGETLHVDGGAHAVGARAAAVVAAGRAA
                     "
     gene            23061..24443
                     /locus_tag="ACTEI_RS12740"
     CDS             23061..24443
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018252074.1"
                     /locus_tag="ACTEI_RS12740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_122977851.1"
                     /transl_table=11
                     /translation="MTQVARSPLAGSQRTSIGDRMDRLPVTALHRSMTAFVGAGLFFDY
                     FDSNLSGTVSKVLQTQFAVGGTTLMLFLASGFIGQFVGSLVLGRLSDRLGRRRAFMLNL
                     LTYSLFTLAGAFSPSAGWLIVTRFLAGLGIGAEQTLADCYLAEVLPPAKRGRLIAWAYS
                     LAFCGVPAVGFTALWLAPRSWLGVAGWRWVFVAGALGTVAVWLLRRGLIESPRWLAARG
                     RIAEADQLVRRLERQAGVVSEPLAPVAAAGVDRRPPGYRVLFSAGQRGRTLVLWTVCLL
                     SVVAYYGFGTLAPQVLAVKGVDVVSGLGYTALTFLGYPFGSLLTVPVIDRVERRVLICG
                     AAVLMAASGLGFGLSADPVAVVVFGFLYTLLSNVFSTASHVFLAEQYPTEFRTTATGAA
                     YSLSRLGAGVLPFVMIPILQHGGAGLLFTVIAGAMAVLVVVVGLFGQRTTGLSVDRHDQ
                     LS"
     gene            complement(24462..25154)
                     /locus_tag="ACTEI_RS12745"
     CDS             complement(24462..25154)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024701.4"
                     /locus_tag="ACTEI_RS12745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR-like C-terminal domain-containing protein"
                     /protein_id="WP_122977852.1"
                     /transl_table=11
                     /translation="MRTSGNDPDPAFRIRWAAYQCLTRHRPGRLDLASVADAAGMPLAE
                     LQRHCGSPDALLGELMLDAYASLACAMEQAASTALRQTASPARQWVAVARAVRSWARTH
                     PAEYALLWEPSHPHYRPSPEVIVAGSRTLLVLAGIVLYARTVAPEQPLPASEQLSTAMA
                     RNVGSLARGLLVGVPLEVIPPLMLAWSQLLASADVAVQRLVQGLLPEPDAFWDHVAHSA
                     GRQLGLPQ"
     misc_feature    25482..25495
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.04"
                     /tool="antismash"
     misc_feature    complement(25483..25496)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.6"
                     /tool="antismash"
     misc_feature    25547..25561
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    25604..25617
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.15"
                     /tool="antismash"
     misc_feature    25711..25727
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            25958..26755
                     /locus_tag="ACTEI_RS12750"
     CDS             25958..26755
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015620405.1"
                     /locus_tag="ACTEI_RS12750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AfsR/SARP family transcriptional regulator"
                     /protein_id="WP_122977853.1"
                     /transl_table=11
                     /translation="MNIWIMGQMLIESGHRSTRFRGGMQGALLAALISAQGQIMPFGTL
                     SEELWGGRQPDGMENALQAHASRLRRKLRALEPERAEARLVARAGGYRLDLDGAATDAI
                     TFASEVAAVQADPGLPPAVVSQRLRAVLSLWRGQVFGGAPVGMIAQAWAARLSAVRIAA
                     LEMLFDNELKLGLHSAIVPELSALVRSEALNERWCEQLMVALYRSGRQAEALGVYQRMR
                     QQMNEELGVDPSPMLRNHERAILAHDDGLLIHGDHRLLRAVAR"
     gene            26850..27818
                     /locus_tag="ACTEI_RS12755"
     CDS             26850..27818
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018252054.1"
                     /locus_tag="ACTEI_RS12755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_203723764.1"
                     /transl_table=11
                     /translation="MPAAADRFTSVVIIANPRAGTTSPAVVADIARRCARRIPDVRSFW
                     TAGRGDGVRLARAVAAADGASVLVIAAGGDGTVREVVEGLVQGTPPGAAPPVLAVVPVG
                     TGNSNYLAQWGEVPWTDALEALLEPAADGPVRAEIRWLDLYRLAETSELILLGACSGLV
                     AEALGVAAGIELTGRARYREALTRAAARHRPYAGRVEVDGDVVHEGPTILANVGGGRYR
                     GGIARLLPFSVLDDGYLDVCVIDATVPAEQVPELITDGGHIGRPGVVYARGKRVTISST
                     DHTPVPFEHDGELVRGDHRRFTVEVLAAALPVACHAGRPVG"
ORIGIN
        1 acgcggcgac ctcggctcgc aggtcatcgg gcgacgcacc gtccagaacc ctacgcatca
       61 gggccgcgcc gatcaccacc ccgtccgcgg actgcgcggc cgcagcggcc tgcgccggcg
      121 tggagatgcc gaatccgatc agcaccggca ggtcggtgac cgccttgatc cgggtggcga
      181 gcggagcggc cgactcggcg agggtgtcgc gttccccggt ggtgtccatg acgctcaccg
      241 cgtacacgaa attgcggctc cgggcgccga tctgggccaa ccgttccggc ggcgtgaccg
      301 gcgcggcgag caggaccagg tcgatgccgg cggaggtcgc ggccgcctcc agtcgatccg
      361 cctcgtcgac cggcacgtcg ggaacgatca gcccggaaat gccggcggcg gcgagccgcc
      421 ggcagaactc ctcggggcca ccggcggagg cggcaggtgc gcggccggag ccgtgcggtg
      481 gggcaaccgg cccgctgccg gagccgtccg ggacagcggt cgttcgggcg tctgcggtgg
      541 tggccgcttc ggtggtgagg gttgtggggc tcggggtggt cgtcggccgg gtgcgcgggg
      601 cggtggccgc ttcggtggcg ggggttgtgg ggctcggggt ggtcgtcggc cgggtgcgcg
      661 gggcggtggc cgcttcggtg gcgggggttg tgcggctcag ggcggttgtc ggcccggcgt
      721 cccggggggt gtctcgggtg gttgccgctc ccgtggtggg aagggaagcg cgcagaggcg
      781 ccggcgccgc actgacgtga cctctgcggg acgtggcggg ctgctcccgg aagaccaggt
      841 tggcgtaggt catggcgatc agcgggatgc ggatacgatc ccgggcggcg gtcagctcgg
      901 tcaggaggga gccgatcgtg acgccacgac gtagcgcctg gtcggaggcc tgctggatgg
      961 tggcgccgtc gagcatcggg tcggagaacg ggaggccgat ctccaccgcg tcggcgccgc
     1021 cctcctggaa ggccagcagg tagtcgatcc agttctcggt gatgccggcg gtcaggtacg
     1081 gattgagccg cttcaccggc cctcacccgc cagcgtcgcc atgtccttgt cgccccggcc
     1141 ggaaagcgtg agcaggacgg tggagccggt cggcaggtcc ggtgtgccgg ctgcccgcag
     1201 cacccaggcc accgcgtggg ccgactccag cgcgcagatg atgccctcgc tgcgggccag
     1261 ccggcgcacc gcggtgatca cctcctcgtc ggtgaccgtg cggtattccg ctcggccgga
     1321 ggcgcccaga tgggcgtgct cgggaccgat gcccggatag tcgaggccgg cggcgatcga
     1381 ctcggcctcc agcacctgcc cgtccggatc ctgcaggacg aatgatcggt aaccgtgcac
     1441 cacgccgggc gtcccgtcgg tcatcgcggc gccaccggcg gcctccaccc cgaccagccg
     1501 ggccggtgtg tcgacgaatc cggcgaacgt gccggccgcg ttggagccgc cgcccacgca
     1561 tgccaccacc acgtcgggca cgctcggggc ctgggcgcgg gcctcctcgc cgatcacccg
     1621 ctgcagttcg cggaccagcc acggataggg gtgtgggccg gcgaccgagc ccagacagaa
     1681 gtgcgcctcg tcgacagcgg ccacccacgc gcgcatcgcc tcgttggtcg cgtccttcag
     1741 cgtgcgactg ccgctggtca ccgggatcac ctcggcgccg agcagctcca tacggaagac
     1801 gttgagctgc tgccgggcga tgtcgcgctc gcccatgtag accgtggccc gcatgccgaa
     1861 cagggcggcc gcggtggcgg tggcgacccc gtgctggccc gcgcccgtct cggcgatcag
     1921 ccgggtcttg cccatccgcc gcgcgagcag cgcctggccg aggacattgt tgatcttgtg
     1981 ggagccggtg tgcgccagat cctcgcgctt gagcagcagc gtgatgccga gctgagcgga
     2041 caggttctcc gccggggtga gggcggtggg gcggccggcg tagtcggcgc gcaggcgggc
     2101 gagacggtcc cggaaggccg ggtcggacca ggcgtcacgg aacgccacgt ccagggcggc
     2161 gcaggccggg atcagggact cggggacgta gcgcccaccg aactgaccga accggccggt
     2221 cgcggtgggc gcactcatca aagacatcgc cgctccaaaa gttatagaac tctgccgccc
     2281 cagcatgcca tgatggggcg gcaaagttct agaactattt tcggaacgga ggtcaggcga
     2341 ccttgtacaa cgcctccgga gtcaccaggc cggcgaacac ccggccgtca tcggtgatga
     2401 gcacgctgaa cagcgatccg ctgagcaggc gtcccttgcc ccacgagccg ctgacctccg
     2461 gcaccatgct cagcagcgcc ttggcctggt cggccttctc gcccgagccc ttgcccacgc
     2521 cggtcagccg gtccagggcg tcggccggga tcttgccgga agcgatggcg gtccagccct
     2581 tgccgatcac cgtgggctcg gcggcctcgg cgccggcggg caccttcgac gcgggacgtg
     2641 ccgtgctctt ctccgtggcg tccgagggct tcacggcctt cgacccgacc tcgtcgatct
     2701 tcgcgcccgg cggcgggttg aaggtgaact gctcggcgtc cggcacctgg aagctgatgg
     2761 tgtcgaaggc gatccggacg gccggcttga ccgcgttctt ggcgtacacc tcgacccgca
     2821 gcgggatgtg ctcctcggcg tcgatcgcca gccgcagctg gcccaccagc gactcggtgt
     2881 ccttcgggct gagcaccagt tcgtatgcgt cacgcccggc gacctgcgcc gcgcccgtgg
     2941 tctggacctt ggtgctcggg gtgatcgcgg cgagagccgc gtcggccgcc tcctgcgggg
     3001 tcgagggcac cgcgctcggc agcgagtgcg gcttggcagt ggtgtcggcc ggcagcttga
     3061 ggtgcatgcc ggtgttcgcc gagctgctcc actgccagag gtccgacccg ttacggatca
     3121 catcggtctc accctgcgcg ctctgcaggg cgagccgcac cttgtcctcg cccgcgtacc
     3181 acacgcgggc ggtgttgctc ccggagacaa gattggtcag gccgcctccc gcggaggcgc
     3241 cgaggctgct cgccaggccc gcgacaccgg gcaggccgag atcggcgctc tgtaccacgg
     3301 tgccggagag gccggcgggt ttggcgttct gcagatccac cagcagctgg gccgcgctgc
     3361 gctccggcag cgacggctca gcgctggcca cgatcgtgcc ggccgccgcg ccgcctccga
     3421 tgacgactat cgccgtggcc cccggcacca gccagcgcag tgcgggcctg gacttccaca
     3481 cggacacgat gtccacctcc cgttggtctg cacccatcct gcttcggcgc cgctgtgatc
     3541 aggctgagag cgacccgtag gggctcagcg gtaagggtcg gcgtgctgag aggtcactga
     3601 gagccggtgc cggccgacga caacgacatg cgactctgaa aggcgtgcgg ttgctggtgg
     3661 tggaggacga ggaacggttg gcggccgccc tgcgccgcgg cctgcaggct gaggggttcg
     3721 cggtggacgt ggcccatgac gggcaggacg ggctggagat ggcccggcac ggcggctacg
     3781 acgcgatgat cctcgacgtg atgctgcccc ggctgtccgg ttaccgcgtg gtgcggcagt
     3841 tgcgcgccga gcggcactgg ctgccggtgc tgatgctgtc cgccaaggac ggcgaatacg
     3901 accaggccga cggcctggac tgtggcgccg acgactatct gaccaagccg ttctcgtacg
     3961 tcgtcttgct ggctcgtctg cgtgccctgc tgcgccgcgg catccaggcc cgtcccgtgg
     4021 tcctcgcgtg cggcgacgtg gagctcgacc cggcggagaa gcgcgtgctc gtgaccggca
     4081 ccgaggtgac cctgacgacc cgcgagttcg ccctgctgga gtacctgatc cgccggcccg
     4141 gtgaggtggt ctcgaagacc gagctgctcg accacgtgtg ggacgcggcg ctggacaccg
     4201 cgccgaacgc cgtcgaggtg tatgtcggct acctgcgtcg caagatcggg cgggagcggc
     4261 tggagacagt gcgcggggcc gggtaccggc tggtgcccct gtccgggatg ccggagaagc
     4321 cgggcgcacc ggcggagagc cgcccgtgac ccgggaagcg gccgtcacgg tgtgcgcctc
     4381 ggcaatgtgc tgccgcacgg ccggacccgc ggtgtgcggt cggtgcgggg cacggcgggc
     4441 cgtgtggcca gcgtggggca gggcagggcc ctgtggccag cgtggggcac ggcgcgacgg
     4501 tgcggtcagc gtggggcacg gcgcgacgct gcggccagcg cgtggcacgg cggggcggtg
     4561 tggccagcgc gggggagggc gcgacgctgt ggccagcgtg gggcacggcg cgacgctgcg
     4621 gcatttcaga cgggtggata gatgcgacgc cgcctgcgtg agctgagcct gcgggcccgc
     4681 ctgctgctga tctccgccgc cgcgctgtcg ttcgggctgg ccgcgggtgg ggtactgctg
     4741 gtcgcggtgc tgaccttcgc gcaggggcgg gccgtgcacg cggaggcgct ggagaccgct
     4801 gagggggtgg cgcggctggt cgaccagggg cagctcaccg acccgatcca ggtcacgccg
     4861 ggcgttcagg tccaggtcat cgacgagcag aaccgggtgc gggcggtctc ggccaccgcg
     4921 gaccggctgg tgccgatcct gtacgtgaag gagctgcgcg tcctgcgcga cggcgagggc
     4981 gtggagatcc cgggggagcg gatcggcttc gacggcgccg cgcgggtcgt caaggtcacc
     5041 gccgggccgg ccacccatcc gctgcggatc ctggtggcgc gctccaccag ccagctcact
     5101 cagagcgtgc acctgctccg ggtcaccctg ctggtcgcgt tcccgctgtt ggtcgcgctc
     5161 ctggcggcgg gtctgtggcg ggcgttgggg gcggcgttgc gtccggtcga cgcgctgcgg
     5221 gccggcgccg aggagatcac cgggggcacc cgggccggcc ggttgccggt gcccggctcg
     5281 cacgacgaga tcaggcgtct cgcgctgacc ctcaacgaca tgctgcaccg gctggacacc
     5341 gcgcgggccc ggcagcgcgc cttcgtggcg gacgccgcgc acgagttgcg cagcccgctc
     5401 accaacatgc ggaccgagct ggaggtggcg cagcggctgc cggacgacac cgactggccg
     5461 gcgctcgccg acgacctgct caccgacgtg cagcggctct cccggctggt ggacgacctg
     5521 ctgttgctgg cccggtcgga cgacggggcg gcgcgggccg tctccggcag gctggaacag
     5581 gtcgatctcg gtcaactggt cggggaggtg gcggcacgct atccgggggt ccggcacgac
     5641 gagtccgccg agccgctgcc gctggtcgcc gagccggacg cgctggcccg ggtggtggcg
     5701 aacctgctcg acaacgcctg ccggcaccga cgctcacggg tgacggtccg caccgccgcg
     5761 tccggcgccg agctgttggt ggtggtcacc gacgacggac cgggcattcc ggcggccgac
     5821 cgggagcggg tcttcgaccg gttcacccgg ctcgacgacg ctcgcgcgcg ggacgccggt
     5881 ggctccgggc tcggcctggc catcgtccgg gaactggtgc gcaggcatgg cggttcggtc
     5941 acgctgggcg atgcggagcc gggattgcgg gtcgaggtac gcctgccgcg cgcccgggag
     6001 gtgatcacga gcgggtgagc gcccgcggaa tcccggaaat tcgcgggaac tcatcggacc
     6061 gtcgcgccga ccaaggaacg tgcccggcag cgggcgacga tacgacggaa gggttccccc
     6121 accatgtcgc tgttcaagcg ttccgcagtg gtggccgccg cggccggagt cctgaccctg
     6181 gcgctcgccg ggccggccgc cgcccacgtg acggtcaacc cgaactcggc caccgccggc
     6241 ggctacgcga aggtgtcgtt ccgggtgccg aacgagtcgg acagcgcctc caccaccaag
     6301 ctcgaggtga acctccccgc cgaccagccg atcgcgtcgg tctcggtcaa gccggtcccc
     6361 ggctggaccg cggtggccca gaagaccaag ctggccaccc cgatcaaggc gcacgacacg
     6421 gagatcaccg aggcggtctc gaagatcacc tggaccgccg cgaagggctc ggagatcaag
     6481 ccgggtgagt tccaggagtt cgacgtgtcg atgggggcgc tgccggagtc ggggcaactg
     6541 gtcttcaaag cactgcagac gtactccaac ggcgacgtgg tgcgctggat cgacgagccc
     6601 accacggacg gatccgagcc ggagagcccg gcgcccgttc tgaagatcgt tccggccgcg
     6661 aacggcagcg ctgccccgtc ggcggccgcc gcggccccgg ccgccgaggc ggatgactcg
     6721 gacgactcgg atgactcgga cggctcgggc agcggcctgg ggctcgccgg tctgatcgcg
     6781 ggactcgtcg ccctgctgct ggccggtctg gcgtacctga aagcgagccg caagccggag
     6841 tccgccgcgc cgggtacgcc tgccgcgagc tgaaaaagga accccggccg agatgtcggg
     6901 ggcgagacgg cagggtgtcg cggccgggaa gatcggtcgt ctgagggagc ccgtggcagc
     6961 gtctcggccg gggaggtcca tcgcgcccgg tgcgccgctg tgcgctgaga cccggatcgc
     7021 gccacggtga cccgcactcc gctgtcgcgg aagaccgacg acggttggct gcagagatca
     7081 gcaagtcccg cgtccgcacc gcaggatcgc gctgatcgtc gtcgcgcgcg gggcgtatca
     7141 gtcgcgttgg cgaggtgggc caccgtggtg acgatctgat ctcgccggag atgcggcgtc
     7201 accgggccga tccgtcggcg gagcggggca tccgcgatcc tcgcggagat ccaggacagc
     7261 ggcgagccgg gccggtacct cgcgaagcgc cgcgtcgtcc ccggcccttc gggcccggag
     7321 aaggtggagc cggttccatc tgaccggcag acgggcggcg tggggtgctg gccgatgcgg
     7381 tcgtgtcgcg gtcctgggtg gtgaactgcg gtgacggcgg atatagcatt ggctgcaaga
     7441 tccagcttta ctaccggggt gaacggatct cgtgtctacg cccggctctg gcatgggctt
     7501 ctcgccgccg tcgtggtgtg ctcgctggtg acccagatcg tgctgacggc gcagggttcg
     7561 cccgattcgg atggtgtggt ggaaccggtg gtgacccggt tcgttcgcat gctcagttac
     7621 ttcacgatcc agagcaacat cctgcttctg atcgtggcgg tcacgctggc ggtgaatccg
     7681 gagcgggacg gcccactgtg gcgggtgatc cgtctggacg cggtgctggg catcatcatc
     7741 accggcttgg tgtatgcgac ggtgctggcg ggccaggcga acccgacggg tgcgggctgg
     7801 tggtcgaatc tggggttcca ctacgtggcg ccgtggtggg cgctgtcggg ctggttgctg
     7861 ttcgggccgc ggtcgcggat ggacaggcgg acgctgggat gggcggtggt ctggccggtg
     7921 ctgtggatcg gctacacgtt cgcccatggt gcggtcactg actggtatcc gtatcccttt
     7981 gccagcgtga cggacatcgg ttatggcgcc gcggtccgca atatggcttt cgtggtggtg
     8041 atcgcgatcc tgttcggggc gatcctgtgg ggtttggacc gccgtttgcc gggtgggcgc
     8101 ccggtcgcct cgaccccggt tcgaaactcg cagcgtgctg agtccgtcgt gagcgctgat
     8161 ccgggtcctg ccgacggcac aggggtcggc aggtcgggcg tcgagcgcca gcgccaggcc
     8221 tgttgatccg gccgctgctt cggatcccgg gcccggaggg acatggagtc gtcggccagg
     8281 cgcgagaacc gttcgagccc cgtgcccggg ctgcgccggc gtagcggagc ggcattcccc
     8341 cgcgtgggca acacctcggc gtcgacgttt cgtcgcggcg acgggttgtg gtccggccgg
     8401 gcgcgtttgc ggtgcggtgc ccgccgctca tccggggagc tgacaccgcc gccgggcggc
     8461 gggcaggcac caccgcccgg cggcacttcg gccgcatcac gccgcgatgt caccgcgtcc
     8521 ggggtgaccg actccgacgc tcacgcggcc ggcgtcacgc cgcccggtgc gcgggtccgg
     8581 tcaccggctc cagcacctct cgcccgccga ggtacggccg cagggccgcg ggcacccgca
     8641 ccgagccgtc cggctgctgg tggttctcca ggatcgggat cagccagcgg gtcgtcgcca
     8701 gcgtgccgtt gagcgtggcc ggggtgcgca gcgtgccgtc ccggccgcgg tggcggatgt
     8761 ccagccgccg tgcctggaac gtcgtgcagt tcgacgtcga ggtcacctcg cggtagcggc
     8821 cctgcgacgg cacccacgcc tcgcagtcgt acttgcgcgc cgcggaggac cccaggtcgc
     8881 cggcggccac gtcgatcacc cggtacggca cctcgacctt ggccagcatc tcctcctgca
     8941 tggcgagcag cgccaggtgc tcgccggccg cgtcgtcggg gtcgcagaag gagaacatct
     9001 ccaccttgtc gaactggtgc acgcgcagga tgccgcgtac gtcacgcccg tgcgagccgg
     9061 cctcccgccg gaagcacgac gaccacccgg cgtagcgcag cgggccgccg cgcaggtcga
     9121 ggacctcgtc gcggtggtac gcggccaggg cgacctcgga ggtgcccacc aggtagaggt
     9181 cgtcggcctc caaccggtac acctcgccgg cgtgcgcgcc gagaaagccg gtgccctgca
     9241 tcgcctccgg tttgaccagc gccggagtga tcgacggcgt gaagccgtgc tcgaccgcct
     9301 gggcgacggc cagttgcagc aggcccagtt gcagcagcgc gccgacgccg gtcaggaagt
     9361 agaaccgcga cccggacacc ttggcgcccc gctcggtgtc gatcgccccg agcgcctcgc
     9421 cgatctccag gtggtccctg ggcgcggtca gtccgggcgg atcgccgacc gtgcgcagca
     9481 ccacgaagtc gtcctcgccg cccggcggga cgccgtccac caccaggttg ggcagggcga
     9541 ggtgggcctg ccggaggacc tcgccggcct tgtccgccgc ggcctgggcc gccttgacct
     9601 cggcggccag ctgccgggtc cgcgccagca gttcggcacg ctcgtcgccg gacgccgcgg
     9661 cgacccgttt gccgagcagc ttctgctcgg tccggagcgc ctcgaaacgc tggacggcga
     9721 cccggcgctc ctcgtcggcg cgcagcagat cgtccacctt cgacaccgac tcaccgcgca
     9781 gccgctggcc ggcacggaac aggtcgggct gttcacgcag cagccgcagg tcaatcatgg
     9841 gcacgtgcca gcagctcgtc gaccttcgcc agcgtgtcgt cggcctgcgc gcacacggcc
     9901 gcgtcgtcgg gcgccccgca gaccatcacg aacgactgca gcacggcctg cagacccgcc
     9961 tgcacctcat cctgcgtggt gtcgctcatc gtccgtctcc tcagacctcg agcgcgttgg
    10021 acgcgcggaa gatgtgggcc agccccgcga tgctcgcccg gccctggaac gccacgtact
    10081 cggggatgca cacgtgcggg tcccacttct gcttgtaggc cagctgggtc tgcgcggggt
    10141 acaccgcctc gccgtgcagc cacagcagct gcatcagcag gtggaaaccg ggactgtgcc
    10201 cggccggcag attctcctcc gccaggccgg tgaacggggt gaaaccgaag tgcagccacg
    10261 ggacgttctc ggactggaag cgctcgatcg cggtgcggtt gatcgcctcc atgatcccgg
    10321 gcacccggtc ggggatgcgc cggctcaggt cgtgcatcca gcccggccgg tcgccgtaca
    10381 ccgggctgta ggagatgtac ccgaccagcc ggtcctcgat cgtgccgacg aacaggcggc
    10441 ggtgctgctg cgcctcgccg ccgtactggc cgacgaggaa ctccagctcg cggctgtgct
    10501 cgcccttcga ggtcagccac accgcgtcca gctcgcgcat ctggtcgtac cagtcgtcca
    10561 gcttggcctc gatgacctgc aggccggccc ggaacgaccg ggagatcttg ttgcgcagct
    10621 gcatgaactt ggtgccggcc agggtgaacc gggccaggtc gacggcccag gaggcgccga
    10681 tctggttgac cgtgaagccg ctgcgggcgt aggcgtcgac gtcgtcacgc tgcagctgta
    10741 cggccaccac cgtgcgctgc tgcgcacgcg cgaagtcgag gaagccgtgg agcaggtcgg
    10801 cgtacgactc cgcgggggcg aacgggccgc cgaactgcac caggtagcgg cccgcggtcc
    10861 gatacgcgac gacgccgggg cgcccgggca gcgtgaaata ctcgttgccc tcgttgactg
    10921 ccaggaaaga cgacgggttg ttcgccccgg gatagtcgcg gatgcaattc agtgcgactt
    10981 ctgcggggga cggtgaatcg gtcatgggaa gtgtccaatc gcgcctgtga gcggacggga
    11041 tagccatcgc cagtagacca tgtggggata gtgccaacaa gggccgctgt cggtgtcaga
    11101 aggtggtcag cgggttgtca gcacgggcct gcagaatcgt tggtgtcagc gaggagagat
    11161 acccgaagtg gtctaacggg gatcggatct ccaggttcga tcgggtgtat gcccgcgtag
    11221 gttcgaatcc tgctctctcc gcggtggtga aaaggggtcc cgtgatgggg cccctttttc
    11281 atttccgggc attgtcagga tagcgtcagc cacgcgtcag agcggtcacc caccatgggt
    11341 cgcggcgagt caactgcgac cgaggagaaa ttgtggtccg aactgccggc cggccggagc
    11401 cattgcgcag ctacggctca tacatcgcag accgggacgt cgacggcgcc ggctgggtct
    11461 acacggtgag cgcccggtcc ctgctggagg acgtcttcac cagtgtcagc ctcaagcgcg
    11521 cgctggagaa cgatcccgac ggcgaggccc tgcagcatcc gtacgtggtc ggccgttgcg
    11581 cggtcgccgg gcccgcggac ctggacgcgt ccctcgacgc ggccgccgag gcggccccgc
    11641 gctgggccgc gatgccgctg gagacccgga tgagcctggg ggagcggttc cgcgccgcgc
    11701 tgcacgagaa ccgcgagacg ttcctggagc tgctgatcgc cgaggcgcac ccgcgcaagc
    11761 tcgccgagtg ggagctcgcc ggtctgctgc agatctacag cccggaaagc ctgtcgttcg
    11821 ccgccagcca gatgcacacc gagttccgcc acggcgaccg gcgcctcatc gtgcgccgcc
    11881 aggcggacgg cgtggtctgc gtcaacccgc cgcagaacgc gccggcctcc agcgcggcgc
    11941 tggccgtgct ggccctgatg gccggcaacg cggtggtggt gcgggccccg cgcagcatcc
    12001 cgctgagcac catgtggctg atgcgggacc tggtcgcgcc gctgctgcgc gagctcggcg
    12061 ccccgcccgg gacgctcaac gtcgtctgca gcaagccccg cgagacgctc gaccgctggc
    12121 tgcggcatcc cggcgtcgac gacatcttct acttcggcgg cagcgcggag gggctgcgct
    12181 tccaggccga gtgcgtcgag cacggcaaga agccgatcct cgaactggcc ggcaacgacg
    12241 gtgtggtcgt gtggcacgac gccgacctgc aactggccgc cgaggcgatc accgagtgct
    12301 tcttcggctc cggccagatc tgcatggtgc ccaactacgt catcgcccac ccgttgatcg
    12361 ccgacgagct gctggagcgg gtggccaagg cggccgccga gatccggccc ggcctgcccg
    12421 gcgaaccgga ctccctgctg tccccggtgc gccgcagcga gaagttcttc gccctgctcg
    12481 aacaggcgag gtcgcggggc gcgcagctgg tctgcggcgg cgagcgcatc gagctggacg
    12541 gcacggtctc ggacaccggc gtgttcctgc agccgaccgt cctgcgggtc gacggtctcg
    12601 ccggggcccg cgacgtggat gcggtgcggc acgagacgtt cttcccgctg ctgccggtcg
    12661 tggtgccgga accggccgcg gacgccgagc tgctggaccg ggtgatccag tacgtcaaca
    12721 gcaacgagta cggcctgcgc aactcgctgt gggccggctc ggacgaggtg gtcggccggt
    12781 tcgtcgccga gatccgcaac ggcggcctgc tgaagatcaa cgactcgcac atcggcttcc
    12841 tgccgtacct gcccacgcac ggcggcaccg gcctgaccag cggggtctac ggcgaggcga
    12901 actacccgat cgtcaagacc tcgcaccagc agggggtcag catctcgacc ggcagcaacc
    12961 cccggcaagc cgtcttcggc ctcggctgat ccgctcgcga acaggagacc tcaccatgcg
    13021 ttccctcgac atcgcccgcg aggcttgtga agcctcgcac cccggcctgc tcaaggccct
    13081 gtccgagcac tcgctcagcg agctggagcg cccgggcggc ccggccgtca aactgttccg
    13141 cgaccacggt ggcgccgggc tgctggtgcc gcgggacttc ggcggggccg gcgccggcgc
    13201 gctcaccgcc gtacggatca atcgggcgct cggcgccgcc agcccgtcgc tgggcgcggc
    13261 ggtgaccatg caccatttca ccgccggcat gctgtacagc ctgaccggct cggccgggcg
    13321 tctcaccggc gcgcagctgg gcctgctgga gcgggtcgcg ggcgagcggc tgctgatggc
    13381 gtccgcctgg gccgagggcc ggtccagcca gaacatcctg gtgccggccg tgaaggcgga
    13441 acctgcgccc ggcggcggtt tcgtggtcaa cggcgtgaag aagccgtgca gcctggcccg
    13501 ttccatggat ctgctgaccg ccagcgtggc ggtgcccggc gacgacggcg agtcgctggc
    13561 ggtgctgctg atcccggccg acacgcccgg catctcggtg catcccttct ggagcaaccc
    13621 ggtgctggcc gccgccgaga gcgaggaggt gcggctggag gacgtgcacg taccggagga
    13681 tctggtgatc cgcacggtgc cggacgaccc gacccgcctc gacgatctgc agtcggccgg
    13741 attcgtctgg ttcgtcatgc tgatctcgtc ggtctacacc ggcgccgcct cggccctgac
    13801 cgaacgggtg ctcaaggccg ggcgcggcag cgtcaccgac cgggccgcgc tgggcgtgca
    13861 gctggactcc gcggtcgggc tgctcgaagg ggtggcccgc gcggtcgacg ccggcgaact
    13921 gaacgaggac gtcgtcgccg ccgcgctggt ggcccgctac gcggtccagg accacctggt
    13981 acgcgtcgcc gacctggcgg tggagacgct cggcggcatc gcctggatca aggacccgga
    14041 gatcgcctac ctggcctccg cggtccgccc gctggccttc cacccgccgt cgcgggccag
    14101 cgccgccgaa cccctgatcg actacttcag cggcgagccg ctgcggctgt cctgaccgcc
    14161 gagaaccgga aggagacccg atgaccacgg tcgcatctcc cgcatccgtc gacaccgagg
    14221 aggagatcct caacctgtac cgggcgcacc tgagcaaggg ccgcgccact ctggcggagc
    14281 tgttcggcag ccacatggag gtggcctccg agggggcctg gatctacacc agcgacggcg
    14341 aggagttcct caacttcggt gggtacggcg tcttcgtcat gggggcgcgg cacccgcggg
    14401 tgctggacgc cgtcacccgg cagctgcgca cccatcccac ctcgacccgg atcctgctgg
    14461 agccgaccgt ggcgcgcgcc gccgaggcgc tgacccggat caccccgccg ggcatggacc
    14521 gggtgcactt ctcgctctcc ggcgccgagg cggtggagac cgcgctcaag ctcggccgcg
    14581 cgcacggccg gcgccggctc gtctccatgt ccggcggata ccacggcaag accctcggcg
    14641 cgctctccgc gaccgccaag gaggtctacc agcggccgtt ccggccgctg ctgccggacg
    14701 tcacccatct gccgtacggc gacgcggacg cgctggggga gcacctgtcc cggtacccgg
    14761 gcgaggtcac cgtcatcgtg gagccggtcc agggcgaggg tggcgtggtg atccccccgg
    14821 ccggctacct caaacaggtc gagcagctgt gccgccggca cggcgccttc ctgatcgtcg
    14881 acgaggtgca gaccggcatg gggcggctcg gctcctggtg gggttgcacc gccgcggatg
    14941 tcgtcccgga cgtgctgctg accggcaagg cgctcggcgg cggcatcctg ccggtgtcgg
    15001 ccgcggtcgc cgaccgcgcg acgttcaagc ccttcgacaa ggacccgtac ctgcacaccg
    15061 cgacgttctc cggccagccg ctgctgatgg ccgcggtgca gggcgcgatc gaggcggtgg
    15121 agcaggacga cctggtcgcc cgtgcggcgg cgctcggcgc ccgcctgctg ccggagatcc
    15181 gcgccatcgt gcaccgcaac atcccggacc tgaccgtcga cgtccgcggc gtgggcctgc
    15241 tgatcggcgt ggagctgatc gaggccggcc tcgccggtga gctgctgatc gagctgttca
    15301 accacggggt ggtggcgaac cactccatga tcggcagctc ggtggtgcgg ttcaccccac
    15361 cggcgaccct caccgagcgt gagctcacga ccttcttcca ggctctcgac ggggccaccc
    15421 gggacctcgt caaccgtcgt acccgaatgc cgaaaggcgg caactgacca tgcgccaggt
    15481 ctccctcgac gcggtgatcc acaacaccgc cgccgattac gtgctgcagc agatcgcccg
    15541 cttcgaccag tatccgacgc tggccccgca cgtgaacgcc accaccgtgc acaccggcct
    15601 gccggagccg gtcggctcct ccagctggga gctgcacttc cgcagcggcc tgctgcgctg
    15661 gaccgagcag gagcggttcc tgaccgacca gctgcgcatc gagttcgccc agaccgacgg
    15721 tgacttcgac gagttctccg gcgtctggca gctgcgccag gacggcgccg acaccgcgct
    15781 cagcttccgg tgcgacttcg acttcggcat cccgtcgctg gagggcatcc tcgacccgat
    15841 cgccgagcgg gtgatccgcg agaccgccgc ctgggcggtg gccggcctgt tcgaccacct
    15901 cgaggtcacc ttcgccgggc ccgcaccggc cgtccccgtg ccggccggcg acgccggctg
    15961 agcccgcacc cttcgagagg ccatctgatg gacgcgaaga atccgttcga aacccgggcc
    16021 accttccggg cgcaccgggc cgagtacctc gtcggcttcg ccgccagcac cgtgctgctg
    16081 atctggcact acgacgagat ccgctggctc cccgccatcg ggctgttcct gtacatcgac
    16141 ctgatcggct acatccccgg cgcgatcgcc ttccaccgca gcaggaccaa gcggatcagc
    16201 aaggtctact actacctcta caacaccatg cacagcatga tcacgcaggc cgcggtcgtg
    16261 gtgctgtggg gcctgctgat cgggtgggag tgggcgctgc tgatcatccc gttccacctg
    16321 ttcggtgacc gcggcgtgtt cggcaacttc ctcaagccgc tcagcctgcc gttcgagccg
    16381 gtcgcctacc ccggttacgc gcgcctgatc gacgcgctgc gctccggggt ggactccagc
    16441 ggctcggcgg ccggcgtgct gggcgcggaa gccccggcgc gggtgccgga cgccgcgccc
    16501 gcggcggccg tccgctgatg gacaccgaga ccctggaggg gcggcggcgc cgggcggtac
    16561 gccacttcgc gtccggcgtg gccgtgctga ccgtcgtcga cgacagcggc acaccgcacg
    16621 gcacgacggt cagcgcggtg accgccatct cccgcgagcc cctgctgctc ggcgtctgcc
    16681 tgcgcctgaa ctcggcgttc gcgcgccggg tccgcgacgg cggccggttc accgtgaacg
    16741 tgttgcgcag cgaccagtac gcgacggcac gctggttcgc cgacccggca cgtccggccg
    16801 ggacggccca gttccgcgac gtcgcgtggg agaccgatgc gctgaccggc gcgccgacgc
    16861 tgaccggatc gctggccacc ctcggctgcc agctggtcga gcggctcgcc ctgggcgacc
    16921 acgacctgct ggtggcgcag gtcctggccg gatcggcgag ctggggatca ccactgctca
    16981 gttacgccgg ccggctgcac gacggcgacc tgcacagcat ggcgccggac agttcggaac
    17041 tgaccgttag gagttctcga tgaccgccgt gatccctccc gaggccgact gggagcaggc
    17101 gcccgggctg ctgaccgggg ccaagaccct ggagctcagc gcggagcggt gcaacctggg
    17161 ttactggctc agcgccgtcg cccagggcac cctgcgcgac cgggcggtga ccgggcacca
    17221 caacgccgcg gtgccgccgt tcatgaagca ggacggcccg ctgcgcgagg cgatgatgct
    17281 ggagctgggg ctgcgctcgg tggccgagga gaaggccacc cgcatcctgt cctactacgt
    17341 cgcgaacgcg ccgggcatcg tggagatgga gttctacgcc acgcagctca tcgacgaggc
    17401 ccgccactcc aaggtgttcc gcgaccacct ggtcgagctg ggcgtcccgg cggccgagct
    17461 gcacgacacg atcgccgaga tgtcccggga gtacgtgccc gaggtgctgc agccggtgga
    17521 ggatctggcc gcccggatca tccgcgacga gcgggacttc gtcggcgggg tggcggtgtt
    17581 caccatcgtc atcgagggcg tgctggcgcc ggccgcggag ctcgccgagc gcaagtggga
    17641 ccggctcgac ccggcggcga gcgagatctc ccgtggcgcc gcgatcgacg agatccggca
    17701 tctgaccgtg ggcagctcga tcatccgcga ccacctgatc cggcacccgg agtaccggcc
    17761 gcggctgatg gagatcctgg cggccgggcg cgagctgtgg gaccgggtgc ccgaccgcaa
    17821 gtacgtgatg taccgcgagg agctgttcca gaagggcatg gcccagcagg ccgacctgct
    17881 gcgcgactac gaggtgtggc cgggccggtt gctgctggac accacccccg aggagcgcta
    17941 cgacatggcc gagcgctgga ccgacgagat ggccgagtcg cggctgcggt tcatggggct
    18001 ggaggacgcg ctcccgctgc tcagcggcac ggacgtggca tgagcgccgg gggtagcggc
    18061 gaccggcacc cggtgctcgc gggcgtgggt gggtggctgc cgtcccgggt ggtcaccaac
    18121 gacgacctgg ccgcccacct ggacacctcc gacgcgtgga tccgcagccg taccgggatc
    18181 ggttcgcggc ggttcgccga gcccggcgtg tcgaccggcg acctggccgt ggcggcgggc
    18241 gcgctggccc tcaagtccag cggtgaggcg caggccgacg cggtggtgct ggccaccgcc
    18301 acgccggacc acccgctgcc gggcaccgcg ccccaggtcg ccgagcggct gggcctgatc
    18361 ggggccgcgg cgttcgacgt ggccgcggtc tgcgcgggct tcgtgtacgg tctggccacc
    18421 gccggcgggc tgatcgccgc ggggaccgcc cgccgggtgc tgctgatcgg cgcggagacc
    18481 ttcaccagca tcgtgaaccc gcgtgaccgc agcaccgcgg tgatcttcgc ggacggcgcc
    18541 ggcgcggtcg tgctgcgcgc gggccggccg gacgagccgg gtgcgctcgg ccccaccgac
    18601 ctgggcagcg acggtgggaa ccatgagctg atcatggtgc cgggcggtgg ctcccgccag
    18661 cgttcctcgg gcgcggatcc cggcccggag gaccacttct tccacatggc cggccgcgac
    18721 gtctaccggc acgccgtcga gcggctgacc tcctcctcgc gggccgccct ggcacacgcg
    18781 gggtggcagg tcacggacgt cgaccggttc gtacctcacc aggcgaacgc gaagatctcc
    18841 gccgcggtcg ccgaccggct gggcctggac gccgaccgcg tgctgtcgaa catcgccgag
    18901 gtgggcaaca cgtcggccgc gtccatcccg ctgctgctcg cccaggccgg cgccgacggg
    18961 cgcctgcagc ccggccaccg ggtcctgctg gccgcgttcg gcggcgggct gacgtggggg
    19021 gcatccaccc tggtctggcc ggacatcacc gcactgaccg tctgatcact gttgtattcg
    19081 gagggattgc catgttcgac accgtgaaga aggtcctcgt cagccgcttc caggttccgg
    19141 cggaggacat cgagccggag gccagcctgg aggatctgga gctcgactcc ctcgatctcg
    19201 tcgagctcgc gaccatcctg gagagcgagt acggcgtccg gatcaccgac gacgagatcg
    19261 ccgaggccaa gcaggtcggc gccgtcgcgg acctggccgc gcgaaaggca gcgacggtct
    19321 gatgccggcg caccgcgtcg ccgttaccgg cctggggctc gtcaccccgg ccggtatcgg
    19381 cgtgaccgag acgtgggagc ggatcctcga cgccgagccg accgccgccc acgaccccga
    19441 gctggccgac aacccggtca ccatctcgtg ccgggtgccc ggcttcgacg gcggcgcgct
    19501 gctcggccgc cgcgcccgca agatggaccg gttcacccag ttcgccgtgg tcgcggcgac
    19561 cgaggcgctc gccgacgcgg gtctggaccc ggcccgctgg gacggcgccc gcgtggccgt
    19621 ggtgctgggc aacgcggacg gcggtttcgc cacggtcgag cagcagcaca gcgtgctgac
    19681 gcagcagggc gccgggttcg tctccgcgct gctgctgccg atgcagctgt ccaacatgct
    19741 cgccggccag ctctccctgc agttcggggc gaccggcccc agcttctgtg tcgcgaccgc
    19801 gtgcgcctcc ggcaccacgg ccatcggcct ggcctgcgat ctgctgcgcc tggaccggtg
    19861 cgacgtggtc atcaccggcg gcagcgaggc cctggtgacg ccgctgatca tggccggctt
    19921 cgcccggatg ggcgcgctgt cacggcgggc cggcgacccg cgggaggcga tgcggccctt
    19981 cgaggtggag cgggacggtt tcgtcggggc cgagggcgcc ggcatcctgg tgctggaacg
    20041 gctggccgac gcccgggccc ggggcgccgg gatccgggcc accgtggacg gcaccgggca
    20101 ctccgccgac gcgcaccacc tcaccgcgcc ggacccggag ggccgggggc tggagcgggc
    20161 gatccgcgcc gcgctcgccg acgccgacgc gggcgccggc gacatcgacc acgtcaacgc
    20221 gcacggcacc gccaccccgc tcggggacct cgccgagtcg cgggccgtcg agcgggtgct
    20281 gcgctcgcgg ccgctggtga gctccaccaa gggcgtcacc gggcacatgc tcggcgccgc
    20341 cggggcggtg gaggccgcgc tcaccgtgct cgcggtgcag cacggtgtgg tgcctccgac
    20401 ggccaacctc gaccggcagg atccggaggt ggaggtcgag gtggcgacca agccggtgca
    20461 ccgccggctg gacgcggcgc tgagcctgtc ggccggcttc ggcgggcaga acgcggccgt
    20521 gctggtgcgc gcgatctgag ccgcgccggc cggcgcggag cccggtggcc ggtcggctgt
    20581 tcgccggccg gccaccgccg ggcgcggcac cggcggcggc cggccgtgac ggcggccggt
    20641 ggcgcggacc gcgaccggag gcgaggatcg ccaccggtgg gccggagagc atccgatgcc
    20701 ggcgggcggc ggtcgccgcc cgcctcagcg tgcggtgatg ctgcgcagcg ccgtcgcggt
    20761 ggcctcgtcg gcggggtaga acgactcgat gcacaactcg gcgacggtga tgtcgagcgg
    20821 ggtgccgaag gtcgccacgg tgctgaagaa cgccagctcg ccgaattccg acttcaaccg
    20881 cagcggtacg aagatgcggg ccgacgcgcc cggctgcggt tccggctggc ccgggtcgca
    20941 cgggtacccc tgcagttctt cctccagcgc ggccagcacg gagtcgccgc tgagcagcac
    21001 ctgacggtgc aggcgggcca gcacgtggga gcgccactcg gcgaagttga ggatgtgcgg
    21061 cgccagcccc tcggggtgca ggctggcgcg cagcacgttg gcgtccggcg gggtgaccag
    21121 ccacggggcg gccatgccga gcagcgtggt gagggccacg ttcgcgtcga cgatgttcca
    21181 gtgccggtcg acgaccaccg ccgggtacgg atcgtgcccg ctgaccacct ggcgcacggc
    21241 ggcgcgcacg gcggtgatgc tcggcgcgtc gagcggcgtc tccaggtagg ccggggcgta
    21301 cccgctggcc agcagcaggc ggttgcgctc gcgcagcgac agctccaggc agtcggccag
    21361 ttgcagcagc acatcgcggc tcggcacgga ccgcccggtc tcgatgaagc tcaggtggcg
    21421 tgcggagatg ccggccttgt tggccagctc cagctggctc agtcggcggc gatggcgcca
    21481 ttgccgtacc agggcgccgg cggtggagcg ggaggcgacg ggtgcattca cggaactcac
    21541 cctggcatgt tcattgctgt ttgtacatgt ttgtaccgag attgtaaaac gatgagtaaa
    21601 ttgaacttca ctctacgtgg tagagcaggg tgagcgtcat gcgcaacgcc ggggtgccgg
    21661 acccctcggc ggcgagctcg acgccgtagt cggtctccca gaagccgcgc gggcgcgggc
    21721 gcacccgcgc cacccggacc cggccgcgca cccggtcgcc gacccggacc gggctcagca
    21781 gccgtacgtc cgagacgccc ttgttgacga cgtggtcggc gccgatgacg tcgaccacct
    21841 ccgacagcat cgccggcacc atggacatca gcaggaagcc gtgggcgacc ggggcgccga
    21901 acggccccgc cgcggcccgt tcggcgtcca cgtggatcca ctggcggtca ccggtgatct
    21961 cggcgaaggc ggtcaccgtc gcggcggaga cgtcgcgcca gtcgctcacc ccgagctcct
    22021 cgcccaccag cgcgggcagc ccggtcaccg gggtgcggcg cgcgctcatg ccgcccggcc
    22081 cgccgcgacg accgcggccg ccctggcgcc caccgcgtgc gcgccgccgt ccacgtgcag
    22141 cgtctccccg gtgacggcgg gcagccagtc cgaccacagc gcgcagatgg cgcggcccac
    22201 cggctccgga tcggtgtggt cccagcccag cgccgcccgc tcccgccagg cctcgacgag
    22261 cgtctcgaac gtgccgatgg cgctggccgc caccgtccgc agcggaccgg cggcgaccag
    22321 gttcacccgg gtgccctgcg gccccagggc gtgcgcgagg tagcggcagc agctctccag
    22381 gccgcccttg gcgacgccca tccagtcgta cccgggccag acctgcccgg cgtcgaagtc
    22441 caggccgacg atcgacccgc cgccggccgc cgccagcagg ggcgcggtcg cccggcccag
    22501 cgcggcgaag gagtacgtgg agacgtgcat cgtgcgggcc acctccggcc acccggcggt
    22561 caggaagccg ccgtccagcg cctccgcggg ggcgaaggcc gccgcgtgca gcaccccgtc
    22621 gagccgtccc cagcgctcct gcacctgcgc ggcgacgcgc gtcaggtgct ccgcgtcggt
    22681 cagatccagc tccagcacgt cgcaccggtg cggaagtcgc gcggcgatct tctcggtgat
    22741 ccgcagcccg cgcccgaagc cggtgagcac gacctcggcg ccctgcagct gagcctggcg
    22801 ggccgcggcg aacgcgatgg agcgttcggt gatgactccg gtgatcagaa gcttcttccc
    22861 gtcgagcagc acagcggttc cccatctctt ccgcagatcg gacgacgtca ttctggtgag
    22921 catttctgac accgggttga cagctgactg ataagcggcg tccgactacc tcgcaggtaa
    22981 tggacccgtt ctgaacagcc atgccagagt tcggaccgat cagcgacgga tctcgggcag
    23041 agaaggagag gaacggttcg atgactcagg tcgcgcgtag cccgctcgcc ggttcccagc
    23101 ggacctcgat cggcgaccgg atggaccgtt tgccggtcac cgccctgcac cgatcgatga
    23161 ccgcgttcgt cggtgccggc ctcttcttcg actatttcga cagcaatctt tccggcacgg
    23221 tttccaaggt gttgcagacc cagttcgcgg tcggcgggac cacgctgatg ctcttcctcg
    23281 cctccgggtt catcggccag ttcgtggggt cgctggtgct gggcaggttg tccgaccggc
    23341 tggggcggcg gcgcgcgttc atgctcaacc tgctgaccta ctcgctgttc accctggccg
    23401 gcgccttctc gccgagcgcg ggctggctga tcgtgacccg gttcctggcc gggctgggca
    23461 tcggggccga gcagacgctg gccgactgct atctcgccga ggtgctgccg ccggccaagc
    23521 ggggccggct catcgcctgg gcctacagcc tggcgttctg cggtgtgccg gcggtcgggt
    23581 tcacggcgct gtggctggcg ccgcgcagct ggctgggggt ggccggctgg cggtgggtct
    23641 tcgtcgccgg ggcgctgggc accgtcgcgg tgtggctgct gcgccggggc ctgatcgagt
    23701 cgccgcgctg gctcgccgcg cgtggccgga tcgccgaggc cgaccagctg gtgcggcggc
    23761 tggagaggca ggccggcgtc gtgtccgagc cgctcgcgcc ggtcgcggcg gccggcgtgg
    23821 accgccgccc gcccggctac cgcgtgctgt tcagcgccgg ccagcgtggg cgcaccctgg
    23881 tgctgtggac cgtctgcctg ctctccgtgg tggcgtacta cgggttcggc acgctggccc
    23941 cgcaggtgct cgcggtcaag ggcgtcgacg tggtgtccgg gctgggctac accgccctga
    24001 cgttcctggg ctacccgttc gggtcactgc tgacggtgcc ggtcatcgac cgcgtcgagc
    24061 ggcgcgtgct catctgcggc gcggcggtgc tgatggccgc gagcgggctc gggttcgggc
    24121 tgtcggccga cccggtggcg gtggtggtgt tcgggttcct ctacacgctg ctgagcaacg
    24181 tcttctcgac cgcgtcgcac gtcttcctcg ccgagcagta cccgaccgag ttccggacca
    24241 ccgccaccgg ggccgcgtac tcgctgtcgc gcctcggcgc cggggtgctg ccgttcgtga
    24301 tgatcccgat cctgcagcac ggcggcgcgg ggctgctgtt caccgtgatc gcgggcgcca
    24361 tggcggtgct ggtcgtcgtg gtcgggctgt tcggccagcg caccacgggc ctgtcggtcg
    24421 accggcacga ccagctgtcc tgagccgccg gcgggcgcgg ctcactgcgg caggccgagc
    24481 tgccgccccg ccgagtgggc cacgtggtcc cagaacgcgt ccggctcggg cagcaggccc
    24541 tgcaccagcc tctgcaccgc cacgtccgcc gaggccagca gctggctcca ggcgagcatc
    24601 agcggtggta tcacctccag ggggacgccg accagcaggc cgcgcgccag gctgccgacg
    24661 ttgcgggcca tggccgtcga cagctgctcg ctcgccggca gcggctgctc cggcgccacc
    24721 gtccgggcgt acagcacgat gccggccagc accagcaggg tccggctgcc ggcgacgatg
    24781 acctccggcg acggccggta gtgcgggtgc gacggctccc agagcagcgc gtactcggcg
    24841 ggatgggtcc gcgcccagga gcgcaccgcg cgggcgaccg cgacccactg ccgggccggg
    24901 ctcgcggtct gccgcagggc cgtcgacgcg gcctgttcca tggcacaggc gaggctcgcg
    24961 tacgcgtcca gcatcagctc gccgagcagc gcgtccgggg agccgcagtg ccgctgcagc
    25021 tcggccagcg gcatcccggc cgcgtcggcc accgaggcca ggtcgagccg gcccgggcgg
    25081 tgccgggtga ggcactggta cgcggcccac cggatccgga aggccgggtc cgggtcgttg
    25141 ccggaagtcc gcatgtgtct cctcattcct ttgccgggtt ccgcccgcac acacgcgccc
    25201 gcaccacagt cggccggcgg cgcggcatga ctatggcgtg tgtcactcgt cgtcggccgc
    25261 ccctgcccgg acgcggcgac tccgcccgcg gcgtcgccgt ccgcgcctga aagggcaggc
    25321 caggccgtta tggttccgcg aaagacgagc gctgtcgatt acccgccagg tagtggaatg
    25381 cgcagtgtcg tactgtatgt cccactcctg agccgagatg aactcatcgt gtctggagtg
    25441 gaactgtccg tcaccgacaa ttcgccggat agccctcatc tctcacgcag cgtgaacccg
    25501 gcggttcgcc gccgcggggt caccgaggct ccttctccgt gcgtcgatct ccggtctcga
    25561 tcgacttgtg ggcgacggcg ccgtccgggg cggctcgacc gcggtcacta tgcgtgtttg
    25621 cgggcgattt caggcactac gtggcgggta atggacggcc cggaaaatgc tgtggtaaga
    25681 acttcgatgt ccttctcatt gatcgatggt cggtaatgtt tcgacattaa ttcggagcgt
    25741 cgaacgataa gacgcgtcac gccgtcaacg gtgacggcca cgcctcgaca cgtcgctgaa
    25801 gggctggacg aacctgtgtc gccgaccggc accgaattgc gtccgacgag cttagccccg
    25861 gctttccgat attttgagaa ccgtccggag caatgcacgt cgcacgcggg atgccggcag
    25921 gtgcatgtcg gtggatcgaa gtcatggggg ttgcgccgtg aacatctgga taatgggcca
    25981 gatgctgatc gagtccggac atcgcagtac gcgattccgg ggtggtatgc agggggccct
    26041 gctggccgcg ctgatcagcg cgcaggggca gatcatgccg ttcggcacgc tgtcggagga
    26101 gctgtggggt ggtcggcagc cggacggtat ggagaacgcg ttgcaggcgc atgccagccg
    26161 gttgcggcgc aagttgcggg cgctggagcc ggagcgggct gaggcgcggc tggtggcgcg
    26221 ggccggtggg taccgtctgg atctggacgg ggcggccacc gacgcgatca cgttcgccag
    26281 tgaggtggcc gcggtgcagg cggatccggg tctgccgccc gcggtggtca gtcagcggtt
    26341 gcgtgcggtg ctgtcgctgt ggcgtggtca ggtgttcggg ggtgctccgg tcggcatgat
    26401 cgcgcaggcg tgggcggccc ggttgagcgc ggtgcggatc gcggcgttgg agatgttgtt
    26461 cgacaacgag ttgaagctgg ggttgcacag cgcgatcgtg ccggagttgt cggcgttggt
    26521 gcgttccgag gcgctcaacg agcggtggtg cgagcagttg atggtggcgt tgtaccggtc
    26581 cgggcggcag gccgaggcgc tcggggtgta tcagcggatg cggcagcaga tgaacgagga
    26641 gctcggggtg gacccgtcgc cgatgctgcg caatcacgag cgggcgatcc tcgcgcacga
    26701 cgacggcctg ctcatccacg gtgaccaccg cctgctgcgc gccgtggccc gctgaccgca
    26761 cgccggtcag cgccgtgtca gccggcggtc agcggcgccg ggcagggtgt gctcaaccgt
    26821 acgttcccca gcgccgaaag ggcgtcccga tgcctgctgc cgccgaccgg ttcacctcgg
    26881 tagtgatcat cgccaatccg cgtgccggca ccacctcccc cgcggtggtg gccgacatcg
    26941 cgcggcggtg cgcccgccgg ataccggacg tacggtcgtt ctggacggcc ggtcgcgggg
    27001 acggtgtccg tctcgcccgc gccgtggccg cggcggacgg cgcatcggtc ctggtcatcg
    27061 ccgctggcgg ggacggcacc gtgcgtgagg tcgtcgaggg cctggtgcag ggcacgccgc
    27121 ccggagcggc cccgcccgtg ctggccgtgg tgccggtggg caccggcaac tccaactatc
    27181 tcgcgcagtg gggcgaggtg ccgtggaccg acgcgctgga ggcgctgctg gagccggccg
    27241 cggacgggcc ggtacgcgcc gagatccgct ggctcgatct ctaccggctc gccgagacct
    27301 ccgagctgat cctgctgggc gcctgctccg gcctggtcgc cgaggcgctc ggggtggccg
    27361 ccggcatcga gctgaccggg cgggcgcgct accgcgaggc actgacccgc gcggccgccc
    27421 ggcaccgccc ctacgccggg cgcgtcgagg tggacggcga cgtggtgcac gagggaccca
    27481 ccatcctggc caacgtcggc ggcggccgct accgaggcgg gatcgcccgg ctcctgccgt
    27541 tctccgtcct cgacgacgga tacctcgacg tctgtgtcat cgacgccacg gtccccgccg
    27601 agcaggtgcc cgagctgatc accgacggcg ggcacatcgg ccgccccggt gtcgtctacg
    27661 cccgcggcaa gcgggtgacc atcagcagca ccgaccacac ccccgtcccc ttcgagcacg
    27721 acggtgagct ggtccgcggc gaccaccgcc gattcacggt cgaggtcctg gccgcggcgc
    27781 tgccggtggc ctgtcacgcc ggccggccgg tcggatgagc ggcgccggcg gcgcgtccgc
    27841 gcagctcgcc cggtgggcgg ccggactacg gccggacgac gtgcccgagc gggtccggga
    27901 cctcgcggcc agccagatcc tgtcccagct cgccgccatc cgggccggtc tgcggcacag
    27961 cgccggcgcc cggctggtga ccgcgttcgg cccgccgctc caaccggatc cccgccgctc
    28021 ggccgccgtc ctggccgccc tcg
//
