LOCUS       NZ_CP023865            21242 bp    DNA     circular CON 27-APR-2024
DEFINITION  Actinoplanes teichomyceticus ATCC 31121 chromosome, complete genome.
ACCESSION   NZ_CP023865
VERSION     NZ_CP023865.1
KEYWORDS    RefSeq.
SOURCE      Actinoplanes teichomyceticus ATCC 31121
  ORGANISM  Actinoplanes teichomyceticus ATCC 31121
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Actinoplanes.
REFERENCE   1  (bases 1 to 8287152)
  AUTHORS   Yushchuk,O., Horbal,L., Fedorenko,V., Ostash,B., Luzhetskyy,A.,
            Kalinowski,J. and Ruckert,C.
  TITLE     Complete genome sequence of Actinoplanes teichomyceticus ATCC 31121,
            type strain of Actinoplanes teichomyceticus and producer of
            teicoplanin, isolated from soil near Nimodi, India
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8287152)
  AUTHORS   Yushchuk,O., Horbal,L., Fedorenko,V., Ostash,B., Luzhetskyy,A.,
            Kalinowski,J. and Ruckert,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-OCT-2017) CeBiTec, Bielefeld University,
            Universitaetsstr. 27, Bielefeld, NRW 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8; canu v. 1.5
            Genome Coverage                   :: 184.1x
            Sequencing Technology             :: Illumina; Oxford Nanopore
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003711105.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 03:18:33
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,294
            CDSs (total)                      :: 7,220
            Genes (coding)                    :: 7,116
            CDSs (with protein)               :: 7,116
            Genes (RNA)                       :: 74
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 104
            CDSs (without protein)            :: 104
            Pseudo Genes (ambiguous residues) :: 0 of 104
            Pseudo Genes (frameshifted)       :: 27 of 104
            Pseudo Genes (incomplete)         :: 92 of 104
            Pseudo Genes (internal stop)      :: 11 of 104
            Pseudo Genes (multiple problems)  :: 22 of 104
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:55:36
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2051275
            Orig. end                         :: 2072517
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21242
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21242
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21242
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11242](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11242
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    188..202
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            458..2503
                     /locus_tag="ACTEI_RS09360"
     CDS             458..2503
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688981.1"
                     /locus_tag="ACTEI_RS09360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_239082264.1"
                     /transl_table=11
                     /translation="MLPSTVRFAALYLVALLAGHLTVLGEPGAMPVIWPATAVAAVWLV
                     DRFDSRWRWVDAGVLGVLTTLALVATGMRAEVACVHGAAAVLGALIFAFAAPRVLPGVW
                     AAGSDPERRGRPLATLADLLRVLLVATAAALGAALVGGLGEQLVTGDDVLARTAIWLVR
                     DVVSVLVFGPAARRLRDLPGARPAWPEAVIAYALSAAAYYYVFSVNERLPIGFVLLAIT
                     VWVALRLPTVLVIGHVMAFGTAAAVFTVHGQGPYASIEASTRGTQTLIVQLYVGVLALV
                     GLALAFSRDERTALIERLRASEHEATEKAGLMTTIVNSMTEGLAILDQHGRLVLRNPAA
                     GRLLGSTSTVAGGTTLGSDYGFFRPDGTPLADADMPYHRALAGADVEPMDVLVRNAAVP
                     EGRIVRFNVARLASPGGPQHVVVVFHDVTADRRHRDELMSFAGVVAHDLLNPLTTIEGW
                     AEVLETELAGYRPAERVARIQRAAARMRTFLNGLLAYTAARDGKLMPTTINLQLMLTDI
                     ANSRYDQAESSGAPPPAFAFGQLDAVEADPVLTRQLLENLIDHALRSVPPGVPPQISAA
                     AQPAPNGMLRIDILDNGRGIPPGMRQAIFTNFHRAEGHGGPGLELAVCKRIVERHGGTI
                     EAVANPYGTGTRMTFTLPAGRSAYARTLENQWQHRPQTGAAASNRG"
     gene            2589..3818
                     /locus_tag="ACTEI_RS09365"
     CDS             2589..3818
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024583.4"
                     /locus_tag="ACTEI_RS09365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GAF domain-containing sensor histidine kinase"
                     /protein_id="WP_122977289.1"
                     /transl_table=11
                     /translation="MAATDIAGHTLEQERLAALHGYEVLDTPAESDFDDIVALAAQLCD
                     KPIAMISLLDENRQWFKARIGVDRCESARQGSICTYAMHGDGLLQIPDARDDPRFAGGA
                     TVTGPPYIRFYAGAPLITPQGRPLGTLCVAAPEPGALTAAQQRGLLALARHVVNHLELR
                     KYARERHDIQVRLRDAERIKDEFIARVNHELRTPLTSIHGYLEMLGDPALPSDARDGFL
                     QRVQRNSDRLLSVVDDMLLAAQVSAGSRDFVRTPADLAALARAAVAGNRPLAEAKGLTM
                     VAEAEEPVFADVDAGRMGQALERLILNAVKFTERGTITVTATERAGTAVLRVRDTGIGI
                     SRQDQFRVLAPFRRAADAERAEVPGIGLGLSIVKAIAEGHDGTVRIESTPGEGSTVAIE
                     VPLAGPYPPG"
     gene            complement(3833..4630)
                     /locus_tag="ACTEI_RS09370"
     CDS             complement(3833..4630)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688983.1"
                     /locus_tag="ACTEI_RS09370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_122977290.1"
                     /sec_met_domain="PEP_mutase (E-value: 2e-67, bitscore:
                     225.9, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAARARFRELHEAGTFVMPNPWDAGSARLLAGLGFAALATTSSG
                     FAATLGKPDQHVTRDELVAHVAALSAAVELPLNVDAERCFADTAAGVAETVELLAAAGA
                     AGISIEDYDPATGRIETPQVGAERVAAAARACARYGIVLTARAENHLYGHDDLDDTVAR
                     LRAYREAGADVVYAPGLRAAADIARVVAEVPAPVNVLAVAGAPAVPELAALGVRRVSTG
                     GSLAWAAYGALRDAARELLTTGTTSFRDRALRGAEIEAAFAAG"
     gene            complement(4668..5174)
                     /locus_tag="ACTEI_RS09375"
     CDS             complement(4668..5174)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688984.1"
                     /locus_tag="ACTEI_RS09375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FBP domain-containing protein"
                     /protein_id="WP_122977291.1"
                     /transl_table=11
                     /translation="MDPISEAEIRASFVNCSKGEAARIKLPPDFRDTPWADLDFLGWID
                     PSAPQRAAIVTPGPAGPVALLLRKAERGGATSAARSSMCQVCLTDHAAGGVSLFTAPLA
                     GAAGRNGNSVGEYLCADLACSLYLRGKRRPRMRLVRFEETLTLTERIDRALAKLAAFTS
                     RVTGA"
     gene            complement(5209..7545)
                     /locus_tag="ACTEI_RS09380"
     CDS             complement(5209..7545)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688985.1"
                     /locus_tag="ACTEI_RS09380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PAS domain S-box protein"
                     /protein_id="WP_239082265.1"
                     /transl_table=11
                     /translation="MAVLLQRPVDNPERLAAVRATGLLDAEEAPGLRRLTRLAARLLGV
                     PTALVSLVLDDRQVFASQLGLPQRWAELGQTPMTHSFCQHVVDGDQPLVVTDARTNPLV
                     RDNRAIDEIGVIAYAGMPIRVDGRVLGAFCAIDSAPRSWSEQELAILEDLAAAVASEIQ
                     LVRAAQHAEATSALVRRILEVSQDAYVSIDADGRVLEWNPAAEQLFGWSRDEAVGVDLS
                     RLVVPEQHRDAHRRGLERVRNSGTSRLAGTRLELPAVDRRGRDFPVELTLQATDTAGGR
                     PVFHAFLHDISARRAAEEQLRRQAELIDAAPAAIIVRDPDGTIRFWNRGAERMYGWPAG
                     AVTGRNIHRLLSTAFPKPLPEVERALQETGSWEGELVHRRSDGQVVVALSRHVSRPSAD
                     GTGYEIIETNTDITDRRRAELAREQSERRFRVQFHQSTIGQVIVGLDGDILHVNDAYAR
                     MVGRSAAELRGYGVVLLTHPEDRAGDTEALAGLFAGEGDAYERTKRLVHADGHVVDVQT
                     GVRLIRDADGHPQHLIGVVQDITEQVRARRERDAAVTVLAERNAQLHRANQLKLDLMGM
                     LSHDIGTPLTAILGFGEMLCEAELPEPLGTLTARIVAAGHRIDELRHNVLAMCQLDAGE
                     LTTVRQPVALAAALRDAADAADTTVPISCPPGVTVLANPAHLRQIVVNFLTNARKYGGG
                     ATAVTVAVEGREVEIGVHDEGPGVPEQLRAHLFERYTRAADAAAEGHGLGLHIVVSLAR
                     ANGGRVAYRPAEPTGSVFALRLEIG"
     gene            complement(7691..8269)
                     /locus_tag="ACTEI_RS09385"
     CDS             complement(7691..8269)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441885.1"
                     /locus_tag="ACTEI_RS09385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_244940674.1"
                     /transl_table=11
                     /translation="MERPMTPDDVVTVIMRRLAEHHRVVPGYVIRDAVEAELRQRFPDV
                     ALPELRVPPEVAAELVAGFGDAATAAEDDAATMPAVLSGDETGRLLAALGLAVHVAAFN
                     LDRDRLHVAQILNGSAAALVALGAAQRAAHADGTSAVLLSPATLRTVRTTMVAVLQGVR
                     HRGWLAEHLDLTATTTMFTDVLTLLGAVP"
     gene            8592..10001
                     /locus_tag="ACTEI_RS09390"
     CDS             8592..10001
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688991.1"
                     /locus_tag="ACTEI_RS09390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_239082266.1"
                     /transl_table=11
                     /translation="MATPTHVEMREEERERQRQSLSTAAARNLTTTTKTPPQMQEITSR
                     WLLRKLPWVQVSGGAYRVNRRRTYRIGDGLLSFTTVGAQVRVVPGELRELSVLSEFEDA
                     DVLAAIADKFVQQEYQPGQVIVEFGSVADHLYLIAHGKVNKVGVGDYGDPVNLGVLADG
                     EAFGEQSLIEGERIWGYTAKAMTAVTLLSIPRAAFTQLLDQNDHLRSHVERFRAKNRRP
                     QNKHGEAAIAISAGHSDEPVLPGTYVDYELSPPEYELSVAQTVLRVHTRVADLYNDPMN
                     QLEQQLRLTVEALRERQEYEMINNRDFGLLHSADLRQRIHTRGGPPTPDDLDELLSMRR
                     STRIFLAHPQAIAAFGRECTKRGIYPPMVEVDGHSMTAWRGVPILPSSKIPITETHTTS
                     ILAMRTGESDQGVVGLHQTGIPDEYQPSLSVRFMGINEQAVMSYLVSAYYSVAVLVPDA
                     LGILDHVELSH"
     gene            10001..11242
                     /locus_tag="ACTEI_RS09395"
     CDS             10001..11242
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF041167.1"
                     /locus_tag="ACTEI_RS09395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_239082267.1"
                     /sec_met_domain="T1TS (E-value: 4.5e-56, bitscore: 189.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLAPDLGREILRDLTGAPPGDLEAVLAAVPAGFAARTGPGAVPG
                     IALAPTGLGTSAARAFRSRPDATPRPAAAHPAWGVPRPAQPWSVSRPVAPRLFCPGPLR
                     DDHALGEQVNDAIVGWAEQVGIYRGRLDRLRAANFGRFMMLTHPATSDPDRLLAAAKCV
                     VAEWAADDYYVDEVSLGADPSVVGSRLANLHALVDPAPLPHGYAAQLAEHHRLRPVSMA
                     FRGAVEHLTRYASVTQLARFRHQMAILFLAWTQEADWHVNRRTPPVWEYLVQRHLNSYL
                     PPMLLVDVLAGYELPPQEYDHPRVRRAFTTAGSAAVLVNDLYSARNESGADHNLPSVLV
                     AGEGLTPREAVLRTVEIHNELMRTFVTLAAELAASGSPPLRRFLADTWAWLGGSREWHA
                     TSGRYHPSEQGEKS"
     gene            11239..12093
                     /locus_tag="ACTEI_RS09400"
     CDS             11239..12093
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688993.1"
                     /locus_tag="ACTEI_RS09400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_122977293.1"
                     /transl_table=11
                     /translation="MSTTAVSPLRTDFERSVAAYWNTHRADPVNLRLGEVDGLYHHHYG
                     VGEPDPAVLDGPAQTREQRIIAELHRLENAQADLLLDHLGPVQPGDALLDGGSGRGGTS
                     MMAHARFGCRVDGVSISEYQVGFANEQAVRRGVAGMVRFHFRNMLDSGFATGSRRAVWT
                     NETTMYVDLFELYAEVARLLPFGGRYVCITGCANDATGRRSKSVSRINEHYTCDIHPRS
                     DYFKALAAHDLVPITVVDLTAATIPYWELRAESEVATGIEEAFLTAYREGSFHYLLIAA
                     DRV"
     misc_feature    complement(12142..12155)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.83"
                     /tool="antismash"
     gene            12176..13981
                     /locus_tag="ACTEI_RS09405"
     CDS             12176..13981
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688994.1"
                     /locus_tag="ACTEI_RS09405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 15 protein"
                     /protein_id="WP_122977294.1"
                     /transl_table=11
                     /translation="MALPIEDYAIIADTQTSALAGRNGSIDWLCVPRFDSGAIFAALLG
                     EAENGHWTIAPAAGPVTTRRRYRDETLVLETEFETATGVARLIDFMPPRTESPSSVVRI
                     VEGVRGTVDFGMELRLRFDYGHVVPWVHREGDALVAVAGPDAAWLRTPVATRGENLATR
                     ADFTVRAGERVPFVLTWRPSHLPPPEPIDAAHELGVTEGYWRGWVSACTYQGEWREAVV
                     RSLLTLKALTYGPTGGIVAAATTSLPEKLGGVRNWDYRFCWLRDATITLQALLYSGFQS
                     EAIAWRRWLLRAIAGNPAELQIMYGVAGERRLDEYRATWLAGYDGNPVRIGNAAAEQFQ
                     LDVYGEVMDALHQGRRAGLTADDPAWGLQVKLMEFVENHWREPDEGIWEVRGGPKQFTH
                     SKLMAWVAADRAVKAIEEFGLPGPRDRWTRLRDDIRADILKKGYDPRRATFTQFYGSVE
                     LDAAMLMVPLVGFLPADDERVRGTVAAIEEHLLVDGFVQRYTQHPDSGVDGLPPGEGAF
                     LACTFWLADNYALMGRHDEARETFHRLLALRNDVGLLSEEYDTRAGRLVGNFPQAFSHV
                     PLIDTARTLTSALAPTEARAEEGLR"
     gene            14053..15036
                     /locus_tag="ACTEI_RS09410"
     CDS             14053..15036
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014688996.1"
                     /locus_tag="ACTEI_RS09410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldo/keto reductase"
                     /protein_id="WP_122977295.1"
                     /transl_table=11
                     /translation="MQTRKLGDLTVSTIGFGAMGMSHGYGPGPDRDANIALLRAAVERG
                     VTLFDTAEVYGPWVNEELVGEALEPFRGQVVIATKFGFAIGADGRESGVDSRPENIRRV
                     ADASLRRLRVDAIDLFYQHRVDPDVPIEEVAGTVRELIEAGKVRHFGMSEAAPATIRRA
                     HAVQPVTAVQSEYSLWWRRPEEGLLDTLAELGIGFVPFSPLGRGFLTGTIGADTVFADN
                     DMRTGLPRFSAEARAANQALVELIGRIAAGKGATPAQVALAWLLAQRPWIVPIPGTRRP
                     ERLAENLGATELALSAADLAEIESAAARIEVRGARYPEQMERMTNL"
     gene            15151..16593
                     /locus_tag="ACTEI_RS09415"
     CDS             15151..16593
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014690883.1"
                     /locus_tag="ACTEI_RS09415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_122977296.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.3e-09, bitscore:
                     35.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDLDVLIVGAGLSGIGAAYYLQRDHPQRSYAIVEARGASGGTWD
                     LFRYPGIRSDSDLHTFGYEFRPWREERVIADAASILRYLRETAAEHGIDRRIRYHHRVI
                     GASWSSPEATWRVAIEHTDTGERSEITCRWLFCAGGYYRYDEGFTPDFPGRDGFRGTIV
                     HPQQWPDDLDHTGRRVAVIGSGATAVTLVPALAETAAHVTMVQRTPSYVVAAPARDPLA
                     PRLRRLLGDERAFAVIRRKNIAQQRAIWQFCQRHPKAARRVIRWLNTRQLPAGYPVDEH
                     FNPPYDPWDQRLCVVPDGDLFRAIRSGKASVVTGRIDTFTADGVRMADGRLVEADVIVT
                     ATGLNVQAFGGVELTVDGEPVKLPETVAYKGMMLSGVPNLAYAIGYTNSSWTLKIGLLC
                     EHFCRLLEHMDRHGHTVCRPRPAGPMATRPFLDFGAGYIQRALGQLPRQGARAPWLTSM
                     NYQSDVKMLREAPVTDPELSFD"
     gene            complement(16691..17584)
                     /locus_tag="ACTEI_RS09420"
     CDS             complement(16691..17584)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018794794.1"
                     /locus_tag="ACTEI_RS09420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /protein_id="WP_122975831.1"
                     /transl_table=11
                     /translation="MPRVAAARRHDLTDVQWAVLEPALPAEPRRGRPPRWTKRQIIDGI
                     RWRVRAGTPWRDVPEVYAPWQTLYRWFRRWQRDGTWAKILARLQTRADAAGDIEWAVSV
                     DSTISRAHQHAAGARRDGDLQKEPPGGVFAEPGDHALGRSRGGFTTKTHLACEQGRKTL
                     STVITAGQRGDSPQFIKVLERIKVYRVGGGRPRTRPDLVLADKAYTSRGNRGYARRRRI
                     RVCIPSKADQDAYRKAKGSKGGRPPAFDPVVYRQRHAVECGINQLKQNRAMATRYDKLA
                     VRFEATVTIAVINQWL"
     misc_feature    17618..17635
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(17704..18543)
                     /locus_tag="ACTEI_RS09425"
     CDS             complement(17704..18543)
                     /GO_function="GO:0030598 - rRNA N-glycosylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0017148 - negative regulation of
                     translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012388.4"
                     /locus_tag="ACTEI_RS09425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ribosome-inactivating family protein"
                     /protein_id="WP_164465886.1"
                     /transl_table=11
                     /translation="MLALVSAIAALAVSPTPASADVSGNFYNITWNIDNLRWGGAEAAT
                     DYYNMIAAVHRAAGHDYQSESNVDETTSQGAQLIGINIVLDGDHIATVYLWSNILYVAG
                     FWSQRTNIHYEFSTYSDVFRQRIRSVAPGAVFSNIGTGSYTNLNGGSQQARASRVFTPE
                     GMYNSILGLYDPGSRTLQQRQQSYVDAIQYISEAARFGLILNRVYDNLLHYTTTPIGAD
                     YAQLENDWDRVSTFIHRVTRGDVPSNYTITVLGQTFRTLAALMFSLRYVMINYGSGR"
     misc_feature    complement(18436..18438)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(18853..20079)
                     /locus_tag="ACTEI_RS09430"
     CDS             complement(18853..20079)
                     /EC_number="2.6.1.9"
                     /GO_function="GO:0004400 - histidinol-phosphate
                     transaminase activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (50-361). E-value:
                     1.8e-33. Score: 108.0. Matches aSDomain:
                     nrpspksdomains_ACTEI_RS09430_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014441888.1"
                     /locus_tag="ACTEI_RS09430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidinol-phosphate transaminase"
                     /protein_id="WP_122977298.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.9e-31, bitscore:
                     108.2, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTAFDTSILHRGAHSASYFDLARAAGDGAEIVDFCIPCNPYFP
                     TPEMFDELTRELKSILKYYPSDSATITKKLAAVLGLHPQTVAMANGSTELITWIDHLLV
                     KESLAIPIPTFGRWTDQPLETGKRVDMFPLQERDGFRLDLEEYVEFIRERRSRVAVICN
                     VNNPDGNYLPRRDVIRFLDALSDLDLVVVDESFIDFSDAERYPSVGPDAVIRPNAVVLK
                     SLGKNFGLHGIRFGYLLANPAIAGRIAKMLPKWNLNSLAEKVVHMIQDHEMEYEESLRL
                     LSRDRRSMGRELQRIPGLTVFPSQGNFFLVKLPNEWSGVALRDFLVANHGIMTRECGNK
                     LGMTSQFMRLVVRPGADVDRLVDGMLDYAQRFHGRSVHESDPLESSSRRWTEQYEERSE
                     YVGRRAAAS"
     aSDomain        complement(18997..19929)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ACTEI_RS09430_Aminotran_1_2.1"
                     /evalue="1.80E-33"
                     /label="ACTEI_RS09430_Aminotran_1_2.1"
                     /locus_tag="ACTEI_RS09430"
                     /protein_end="361"
                     /protein_start="50"
                     /score="108.0"
                     /tool="antismash"
                     /translation="DELTRELKSILKYYPSDSATITKKLAAVLGLHPQTVAMANGSTEL
                     ITWIDHLLVKESLAIPIPTFGRWTDQPLETGKRVDMFPLQERDGFRLDLEEYVEFIRER
                     RSRVAVICNVNNPDGNYLPRRDVIRFLDALSDLDLVVVDESFIDFSDAERYPSVGPDAV
                     IRPNAVVLKSLGKNFGLHGIRFGYLLANPAIAGRIAKMLPKWNLNSLAEKVVHMIQDHE
                     MEYEESLRLLSRDRRSMGRELQRIPGLTVFPSQGNFFLVKLPNEWSGVALRDFLVANHG
                     IMTRECGNKLGMTSQFMRLVVRPGADVDRL"
     gene            20195..20392
                     /locus_tag="ACTEI_RS09435"
     CDS             20195..20392
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ACTEI_RS09435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_122977299.1"
                     /transl_table=11
                     /translation="MRGILRTGLIGFVVLGSVTVADEARATPGAGVAARTVGQRAVHGA
                     GPARHEWAAAPGGTVSTRER"
ORIGIN
        1 caggccgggt cgccgtcgca gtcgaccacc tcggtctccc cctccaggtc gcggaccagg
       61 ccgccgaccg acgcggtgcg gccggcgtcg gccagccgca cgccaccgcc gcggccgcgg
      121 acggtctcca gcaggccgcg ccgctgcagc gtctgcacca ccttggcgag gtggttgcgg
      181 ggtacggcga gagcctcggc cagctcgtcg acggtcagcc ggtcggcgcg tgccgcactg
      241 agcatcagca cccgcagcgc gatgtcggtg gagcggttga gtcgcacgtg atcaccgtag
      301 gctaaaagga ctctgagata cctcttttga gaggggtttc acgctgcgcc cggtgcagga
      361 ctttgtgcct cgatgttcag cctttcgcgg ttgctgccga accagggggt tggaggcggc
      421 caccttcgac acgaggcgaa caaagatgag tcttcggatg ttgcccagca ccgtgcgttt
      481 cgcggcgctc tacctcgtcg cgttgctcgc cggccacctc accgtcctgg gcgagccggg
      541 agccatgccg gtgatctggc cggccaccgc ggtcgccgcc gtctggctgg tcgaccgctt
      601 cgactcgcgc tggcggtggg tggacgccgg cgtgctcggc gtgctcacca cgctcgctct
      661 cgtggccacc gggatgcgcg ccgaggtcgc ctgcgtgcac ggcgcggccg cggtgctcgg
      721 cgcgctgatc ttcgcgttcg ccgcgccccg cgtgctgccc ggcgtctggg cggcgggcag
      781 tgacccggag cgccgtggcc ggcccctggc caccctcgcc gacctgctgc gggtgttgct
      841 ggtggcgacc gccgccgcgc tcggcgccgc gctggtcggc gggctcggcg agcagctggt
      901 caccggcgac gacgtactcg cccggaccgc gatctggctg gtccgtgacg tggtcagcgt
      961 gctggtcttc ggccccgccg cgcggcggct gcgggacctg ccgggggccc ggcccgcctg
     1021 gccggaggcg gtcatcgcgt acgccctctc ggcggccgcc tactactacg tgttctcggt
     1081 caacgagcgc ctgccgatcg gcttcgtgct gctggcgatc acggtgtggg tcgcgctgcg
     1141 cctgcccacc gtgctggtga tcgggcacgt catggccttc gggaccgccg ccgccgtgtt
     1201 caccgtgcac gggcaggggc cgtacgcgtc gatcgaggcc agcacccgcg gcacccagac
     1261 cctgatcgtc cagctgtacg tcggggtgct ggccctggtc ggcctggccc tggcgttcag
     1321 ccgggacgag cggaccgcgc tgatcgagcg gctgcgcgcc tccgagcacg aggccaccga
     1381 gaaggccggc ctgatgacca cgatcgtcaa ctcgatgacc gaggggctgg ccatcctcga
     1441 ccagcacggc cgcctggtgc tgcgcaaccc ggccgccgga cggctgctgg gcagcaccag
     1501 cacggtcgcc gggggcacca cgctgggcag cgactacggc ttcttccgcc cggacggcac
     1561 cccgctggcc gacgccgaca tgccgtacca ccgggcgctg gccggcgccg acgtggaacc
     1621 gatggacgtg ctggtccgca acgcggcggt gcccgagggc cggatcgtcc ggttcaacgt
     1681 ggcccggctg gccagcccgg gcggtccgca acacgtggtg gtggtcttcc acgacgtcac
     1741 cgccgaccgc cggcaccgtg acgagctgat gtcgttcgcc ggggtggtgg cgcacgacct
     1801 gctcaacccg ctgaccacca tcgagggctg ggccgaggtg ctggagaccg agctggccgg
     1861 ataccggccg gccgagcggg tcgcccggat ccagcgcgcc gcggcccgga tgcggacctt
     1921 cctgaacggg ctgctcgcct acaccgccgc ccgcgacggc aagctgatgc ccaccacgat
     1981 caacctgcag ctgatgctca ccgacatcgc caacagccgg tacgaccagg cggagagcag
     2041 cggcgccccg ccacccgcgt tcgcgttcgg ccagctggat gcggtcgagg ccgacccggt
     2101 gctgacccgg cagctgctgg agaacctgat cgaccacgcg ctccgcagcg tcccgccggg
     2161 agtgccgccg cagatcagcg ccgcggcgca gccggccccg aacggcatgt tgcgcatcga
     2221 catcctggac aacgggcgcg gcatcccgcc cggaatgcgc caggccatct tcaccaactt
     2281 ccaccgggcc gaggggcacg gcggtcccgg gctggagctg gcggtctgca aacggatcgt
     2341 ggagcggcac ggcgggacca tcgaggcggt cgccaacccg tacggcaccg gcacccggat
     2401 gacgttcacg ctgccggccg ggcgctcggc gtacgcccgc accctggaga accagtggca
     2461 gcaccgcccg cagaccggcg cggccgcatc gaatcgcggg tagatctcat caccggggcc
     2521 gggtggccga ccaataccgg tgagggacgt gctccgaagg acccggggta cggcgaagga
     2581 gggttcggat ggcggccacg gacatcgccg gccacacgct cgaacaggaa cgcctcgccg
     2641 ccctgcacgg ctacgaggtg ctggacaccc cggcggagag cgacttcgac gacatcgtcg
     2701 cgctcgccgc gcagctgtgc gacaagccga tcgccatgat cagcctgctc gacgagaacc
     2761 gccagtggtt caaggcgcgg atcggcgtgg accggtgcga gagcgcccgg cagggctcga
     2821 tctgcacgta cgccatgcac ggcgacggcc tgctgcagat cccggacgcc cgcgacgatc
     2881 cccgcttcgc cggcggcgcg accgtcaccg gcccgccgta catccgcttc tacgccgggg
     2941 cgccgctgat caccccgcag ggccggccgc tgggcaccct ctgcgtcgcc gcgccggagc
     3001 cgggcgcgct caccgcggcc cagcagcgcg gcctgctggc cctggcccgg cacgtggtca
     3061 accacctgga gctgcgcaag tacgcccggg agagacacga catccaggtt cggctgcgcg
     3121 acgccgagcg gatcaaggac gagttcatcg cccgggtcaa ccacgagctg cgtaccccgc
     3181 tcacctcgat ccacggctac ctggagatgc tcggcgaccc ggcgctgccg tccgacgccc
     3241 gcgacggctt cctgcagcgg gtgcagcgca actccgaccg gctgctctcg gtggtcgacg
     3301 acatgctgct ggccgcgcag gtcagcgccg gcagccggga cttcgtccgg accccggccg
     3361 acctggccgc gctggcccgc gccgcggtcg ccgggaaccg gccgctggcc gaggcgaagg
     3421 ggctgaccat ggtcgcggag gcggaagagc cggtcttcgc cgacgtcgac gcggggcgga
     3481 tgggccaggc cctggaacgg ctgatcctca acgcggtcaa gttcaccgaa cggggcacga
     3541 tcacggtgac cgcgaccgag cgggccggga cggcggtgct gcgggtgcgc gacaccggga
     3601 tcgggatcag ccgccaggac cagttccggg tgctcgcgcc gttccgccgc gccgccgacg
     3661 ccgagcgggc cgaggtgccg gggatcgggc tgggcctgag catcgtcaag gcgatcgccg
     3721 aggggcacga cgggacggtg cgcatcgaga gcaccccggg cgagggcagc acggtggcca
     3781 tcgaggtgcc gctcgccggg ccgtacccgc ccggctgaac gccccggacc ggtcacccgg
     3841 cggcgaacgc cgcctcgatc tccgcgccgc gcagcgcgcg gtcgcggaac gacgtggtcc
     3901 cggtggtgag cagctcgcgg gccgcgtcgc gcagggcgcc gtaggcggcc caggccagcg
     3961 acccgccggt ggagacccgc cggacaccca gcgcggccag ttccggcacg gccggggcgc
     4021 ccgccacggc cagcacgttc accggcgcgg gcacctcggc gaccacccgg gcgatgtccg
     4081 ccgcggcccg caggcccggc gcgtacacca cgtccgcgcc ggcctcccgg taggcccgca
     4141 gccgggccac cgtgtcgtcg agatcgtcgt gcccgtagag gtggttctcc gcgcgggcgg
     4201 tcagcacgat gccgtaccgg gcgcaggccc gcgccgccgc ggccacccgc tccgccccga
     4261 cctgcggggt ctcgatccgg ccggtcgccg ggtcgtagtc ctcgatcgag atgccggccg
     4321 cgccggccgc ggccagcagc tccaccgtct cggcgacccc ggccgcggtg tcggcgaagc
     4381 agcgctcggc gtccacgttc agcggcagct cgaccgcggc gctgagcgcg gccacgtgcg
     4441 ccaccagctc gtcccgggtg acgtgctggt ccggcttgcc gagcgtggcc gcgaagccgg
     4501 acgacgtggt ggccagcgcg gcgaagccca ggccggccag cagccgggcc gacccggcgt
     4561 cccacgggtt cggcatgacg aacgtccccg cctcgtgcaa ttcccggaat cgtgcccgcg
     4621 cagcagtcat gatccgaccc tagacggtcg gcccgggacg ccgccggtca cgcgccggtg
     4681 acccgcgacg tgaacgcggc cagcttcgcc agcgcccggt cgatcctctc ggtcagggtc
     4741 agcgtctcct cgaagcgcac cagccgcatc ctcggccgcc gcttgccgcg cagatacagc
     4801 gagcaggcca ggtccgcgca caggtactcg ccgaccgagt tgccgttgcg gccggccgcg
     4861 ccggccagcg gggcggtgaa caggctgacg ccgccggccg cgtggtcggt caggcacacc
     4921 tggcacatgc tggagcgggc cgcgctcgtc gcgccgccgc gttccgcctt gcgcagcagc
     4981 agcgccaccg ggccggccgg gccgggcgtc acgatcgccg cgcgctgcgg ggcggacggg
     5041 tcgatccacc cgaggaagtc caggtcggcc cacggggtgt cgcggaagtc ggggggcagc
     5101 ttgatccgcg ctgcctcacc cttgctgcag ttgacgaacg aggcgcggat ctccgcctcg
     5161 ctgatcgggt ccatggggtc ggaccctggc acatccggcc cgcggacgtc acccgatttc
     5221 caggcgcagg gcgaacacgc tgccggtcgg ctcggccggc cggtacgcca cccgcccgcc
     5281 gttcgcccgc gccaggctga ccacgatgtg caggcccagc ccgtgcccct cggcggcggc
     5341 gtccgcggcc cgggtgtacc gctcgaacag gtgcgcccgc agctgttcgg ggaccccggg
     5401 gccctcgtcg tgcacaccga tctccacctc gcggccctcg accgcgacgg tcaccgcggt
     5461 ggcgccgcca ccgtacttgc gggcgttggt caggaagttc accacgatct ggcgcagatg
     5521 ggccgggttg gccagcaccg tcaccccggg cgggcagctg atcggcaccg tggtgtcggc
     5581 cgcgtccgcc gcgtcgcgca gcgccgccgc cagcgcgacc ggctggcgta cggtggtcag
     5641 ctcgccggcg tccagctggc acatcgccag cacgttgtgc cgcagctcgt cgatccggtg
     5701 gccggcggcg acgatgcggg cggtgagcgt gcccagcggc tcgggcagct cggcctcgca
     5761 cagcatctcg ccgaagccca ggatggcggt cagcggggtg ccgatgtcgt gcgacagcat
     5821 ccccatcagg tccagtttga gctggttcgc gcggtgcagc tgcgcgttgc gctcggccag
     5881 cacggtcacc gcggcgtccc gctcgcgccg cgcccggacc tgctcggtga tgtcctggac
     5941 cacgccgatc aggtgctgcg ggtggccgtc ggcgtcgcgg atcaggcgca ccccggtctg
     6001 cacgtccacc acgtgaccgt cggcgtgcac caggcgcttg gtccgctcgt acgcgtcgcc
     6061 ctccccggcg aacagcccgg ccagcgcctc ggtgtcgccg gcgcggtcct ccgggtgggt
     6121 gagcaggacc acgccgtacc cgcgcagctc ggcggccgac cggccgacca tccgcgcgta
     6181 cgcgtcgttg acgtgcagga tgtcgccgtc cagcccgacg atcacctgcc cgatcgtgga
     6241 ctggtggaac tgcacccgga aacgccgctc gctctgctcg cgggccagct cggcccgccg
     6301 gcggtcggtg atgtcggtgt tcgtctcgat gatctcgtag ccggtcccgt ccgccgacgg
     6361 gcgcgacacg tgccggctga gcgccaccac gacctgcccg tcggagcgcc ggtgcaccag
     6421 ctcaccctcc caggaaccgg tctcctggag ggcccgctcc acctcgggca gcggcttggg
     6481 gaaggcggtg gacagcagcc ggtggatgtt gcgcccggtc accgcgccgg ccggccagcc
     6541 gtacatccgc tccgcgcccc ggttccagaa ccggatcgtc ccgtccgggt cccggacgat
     6601 gatcgccgcc ggcgcggcgt cgatcagctc ggcctgccgc ctcagctgtt cctcggcggc
     6661 ccgccgggcg ctgatgtcgt gcaggaacgc gtggaagacc ggccggcccc cggccgtgtc
     6721 ggtggcctgc agggtcaact cgaccgggaa gtcccgcccg cggcggtcca ccgcgggcag
     6781 ctccagccgg gtgccggcca gccgggacgt cccggagtta cgcacccgct ccagcccgcg
     6841 ccggtgcgcg tcgcggtgct gttcgggcac gaccagccgg ctcaggtcca cgcccacggc
     6901 ctcgtcccgg gaccagccga acagctgctc ggcggccggg ttccactcca gcacccggcc
     6961 gtcggcgtcg atcgagacgt acgcgtcctg ggagacctcc aggatccggc gtaccagcgc
     7021 ggacgtcgcc tcggcgtgct gcgccgcccg gaccagctga atctccgagg cgaccgccgc
     7081 ggccaggtcc tccaggatcg ccagctcctg ctccgaccag gagcgcggcg cgctgtcgat
     7141 ggcgcagaac gcgccgagca cccgcccgtc gacccggatc ggcatcccgg cgtaggcgat
     7201 caccccgatc tcgtcgatcg cccggttgtc ccgcaccagc gggttcgtcc gggcgtcggt
     7261 gaccaccagg ggctggtcgc cgtccacgac gtgctggcag aacgagtggg tcatcggggt
     7321 ctgcccgagc tcggcccagc gctgcggcaa cccgagctgg ctggcgaaca cctgccggtc
     7381 gtcgagcacc agcgacacca gcgcggtggg caccccgagc aggcgcgcgg ccagccgagt
     7441 cagccggcgt aggccgggcg cctcctcggc gtccagcagg ccggtcgccc gtaccgccgc
     7501 gagccgttcc gggttgtcca ccggcctctg caggagcact gccatgttcg gttgatcggc
     7561 accgggtgcc gatacttgag cggcgcggcc cggccgaacc cggcgggcgc ccggccgggt
     7621 gcccgccggt cgggcggacc ggtcccggcc cgctgatcgg gggcggcgtg ccggtccggt
     7681 gcacccgcgg tcagggcacc gcgccgagca gggtcaggac gtcggtgaac atcgtggtgg
     7741 tggcggtcag gtcgaggtgc tcggcgagcc agccgcggtg acgcaccccc tgcagcacgg
     7801 cgaccatggt ggtccgcacg gtgcgcaggg tggccggcga gagcagcacc gccgaggtgc
     7861 cgtcggcgtg cgccgcgcgc tgcgcggcac ccagggcgac cagcgcggcc gccgagccgt
     7921 tcaggatctg ggcgacgtgc aggcggtccc ggtcgaggtt gaaggcggcc acgtggacgg
     7981 ccagcccgag cgccgccagc agccgcccgg tctcgtcgcc gctgagcacg gccggcatgg
     8041 tcgccgcatc gtcctcggcc gcggtggcgg cgtcgccgaa cccggccacc agctcggccg
     8101 cgacctcggg cggcacccgc agctcgggga gcgcgacgtc cgggaaccgc tggcgcagct
     8161 cggcctcgac cgcgtcgcgg atgacgtagc cggggaccac ccggtggtgc tcggcgagtc
     8221 ggcgcatgat caccgtgacc acgtcgtcgg gggtcatcgg ccgctccatc cgcctaccgt
     8281 atccgccggt ccggtcggtg gacggcgggc agcgtgaccc cggcggtgcc gccgggtggt
     8341 cgcccggtgg gccgccggcc gcgcggtggg ccgtccgccg cgtcgttgac agcctgacca
     8401 tcggcccggc ccggggtttg ctgaggcacg gcgggcgggg gatcgccggg gcccgatgcc
     8461 ggcgatgggc gcgcctgtcg gcgcaggtca cagcatgttc ctagattccg cgaaacccga
     8521 caaaacagtc ggatatgcga tagaacggcc gtaagtccgc atgaggaaga ccgacgaacg
     8581 gggtacgagc ggtggccact ccgacacacg tggagatgcg cgaggaagag cgggagcggc
     8641 agcgccagag cctcagcacg gcggcggccc ggaacctgac caccaccacc aagacgcctc
     8701 cgcagatgca ggagatcacc tcccggtggc tgctgcgcaa gctgccctgg gtgcaggtgt
     8761 ccggcggggc gtaccgggtc aaccggcgca ggacctaccg gatcggcgac ggcctgctca
     8821 gcttcaccac cgtcggcgcc caggtgcgcg tggtgcccgg cgagctgcgg gagctctccg
     8881 tgctcagcga gttcgaggac gccgacgtgc tggccgccat cgcggacaag ttcgtgcagc
     8941 aggagtacca gccgggccag gtgatcgtgg agttcggctc ggtcgccgac cacctctacc
     9001 tgatcgcgca cggcaaggtg aacaaggtcg gcgtcggcga ctacggcgac ccggtcaacc
     9061 tgggcgtgct ggccgacggc gaggcgttcg gcgagcagtc gctcatcgag ggcgagcgga
     9121 tctggggcta caccgccaag gcgatgaccg cggtcaccct gctgagcatc ccccgtgccg
     9181 cgttcaccca gctgctcgac cagaacgacc acctgcgctc gcacgtggaa cgcttccggg
     9241 ccaagaaccg ccgcccgcag aacaagcacg gcgaggcggc catcgcgatc agcgccggcc
     9301 actccgacga gccggtcctg cccggcacgt acgtcgacta cgagctgagc ccgcccgagt
     9361 acgagctgag cgtcgcccag accgtcctgc gcgtgcacac ccgcgtcgcc gacctctaca
     9421 acgacccgat gaaccagctc gaacagcagc tgcgcctgac cgtcgaggcg ctgcgcgagc
     9481 gccaggagta cgagatgatc aacaaccgcg acttcggcct gctgcacagc gccgacctga
     9541 ggcagcgcat ccacacccgg ggcggcccgc ccaccccgga cgacctcgac gagctgctca
     9601 gcatgcggcg cagcacacgg atcttcctgg cccacccgca ggccatcgcg gcgttcggcc
     9661 gggagtgcac caagcgcggc atctacccgc cgatggtgga ggtggacggg cacagcatga
     9721 cggcctggcg cggtgtgccg atcctgccca gcagcaagat accgatcacc gagacgcaca
     9781 ccacctcgat cctggcgatg cgtaccggcg agtccgacca gggcgtggtc gggctgcacc
     9841 agaccggcat cccggacgag taccagccca gcctctccgt gcgattcatg gggatcaacg
     9901 agcaggcggt gatgtcctac ctggtcagcg cgtactactc ggtcgccgtg ctggtgccgg
     9961 acgcgctggg catcctggac cacgtcgagc tgtcgcactg atgccgctcg cacccgatct
    10021 cggccgggag atcctgcgcg acctcaccgg ggcgccgccc ggcgatctcg aggcggtgct
    10081 cgccgccgta ccggcgggtt tcgccgcgcg gaccggcccc ggcgccgtgc cggggatcgc
    10141 tctcgccccg accggcctgg gcacctcggc cgcgcgcgcc ttccgatccc ggccggacgc
    10201 gacgccgcgt ccggccgcag cgcacccggc gtggggcgtg ccgcgaccgg cgcagccgtg
    10261 gagcgtgtcc cggccggtgg cgccgcggct gttctgcccc ggcccgctgc gcgacgacca
    10321 cgcgctgggc gagcaggtca acgacgccat cgtcgggtgg gccgagcagg tcggcatcta
    10381 ccgcggccgg ctggaccggc tgcgcgcggc gaacttcggc cggttcatga tgctcaccca
    10441 cccggccacc agcgacccgg accggttgct ggccgcggcc aaatgcgtgg tcgccgagtg
    10501 ggcggcggac gactactacg tggacgaggt gtcgctgggc gccgacccgt cggtggtcgg
    10561 ctcccggctg gccaatctgc acgcgctggt cgacccggcg ccgctgcccc acggatacgc
    10621 cgcccagctg gccgagcacc accggctccg gccggtctcg atggcgttcc gcggcgccgt
    10681 cgagcacctg acccggtacg cgtcggtgac ccagctggcc cgcttccgcc accagatggc
    10741 gatcctcttc ctggcctgga cgcaggaggc cgactggcac gtcaaccgtc gcaccccgcc
    10801 ggtctgggag tacctggtgc agcggcacct caacagctac ctgccgccga tgctgctggt
    10861 cgacgtgctc gccggctacg agctgccgcc gcaggagtac gaccatccgc gggtgcgccg
    10921 ggcgttcacc accgcgggca gcgcggccgt gctggtcaac gacctgtact cggcacggaa
    10981 cgagtccggc gccgatcaca acctgcccag cgtgctggtg gccggcgagg gcctgacgcc
    11041 gcgcgaggcg gtgctgcgca ccgtggagat ccacaacgag ctgatgcgga ccttcgtgac
    11101 cctggccgcg gaactcgcgg cgtccggctc gccgccgctg cggcgcttcc tcgccgacac
    11161 ctgggcgtgg ctgggcggca gccgggagtg gcacgccacc agcggccggt accacccgtc
    11221 cgagcaaggg gagaaatcat gagcacgact gccgtctcgc cgctgcgcac cgacttcgaa
    11281 cgatccgtgg cggcctactg gaacactcac cgcgccgacc cggtcaacct gcgcctcggc
    11341 gaggtggacg gcctctacca ccaccactac ggggtcggcg agcccgatcc ggccgtgctc
    11401 gacggcccgg cgcagacccg tgagcagcgg atcatcgcgg agctgcaccg gctggagaac
    11461 gcgcaggccg acctgctgct cgaccacctc gggccggtcc agccgggcga cgcgctgctg
    11521 gacggcggct ccggccgggg cgggaccagc atgatggcgc acgcccggtt cggctgccgg
    11581 gtcgacggcg tgtccatctc cgagtaccag gtcggcttcg ccaacgagca ggcggtccgg
    11641 cgcggcgtcg ccggcatggt ccggttccac ttccgcaaca tgctggactc cgggttcgcg
    11701 accgggtccc ggcgggcggt ctggaccaac gagacgacga tgtacgtcga cctgttcgag
    11761 ctgtacgccg aggtcgcccg gctgctgccc ttcggcggcc gctacgtgtg catcaccggc
    11821 tgcgccaacg acgcgaccgg ccggcgctcc aaatcggtca gccggatcaa cgagcactac
    11881 acctgcgaca tccacccccg cagcgactac ttcaaggcgc tcgccgcgca cgacctggtc
    11941 ccgatcaccg tggtcgacct gaccgcggcg accatcccgt actgggagct gcgcgccgag
    12001 tccgaagtgg ccaccgggat cgaggaggcg ttcctcacgg cgtaccggga gggcagtttc
    12061 cactacctcc tgatcgccgc cgaccgggtc tgaccacccc ggccggttgg ccgccgccgg
    12121 gggcgacgcc cccggcggcg gtttttcgtg aatatgttcc gggtagtcgc ctggcatggc
    12181 cctgccgatc gaggactacg cgatcatcgc cgacacgcag acctccgccc tggccgggcg
    12241 caacggttcc atcgactggc tgtgcgtgcc ccgcttcgac tccggcgcca tcttcgcggc
    12301 gctgctcggc gaggcggaga acggccactg gacgatcgcg ccggccgccg gcccggtcac
    12361 cacccgccgc cggtaccgcg acgagacgct ggtgctggag accgagttcg agaccgcgac
    12421 cggggtggcg cggctgatcg acttcatgcc cccgcggacc gagtcgccgt cctcggtggt
    12481 gcggatcgtc gagggcgtgc gcggcaccgt cgacttcggc atggagctgc ggttgcgctt
    12541 cgactacggg cacgtcgtgc cgtgggtcca ccgggagggc gacgcgctgg tcgcggtcgc
    12601 cgggccggac gcggcctggc tgcgcacgcc ggtggccacg cgcggcgaga acctggcgac
    12661 ccgggccgat ttcaccgtac gggccggcga gcgggtcccg ttcgtgctga cctggcgccc
    12721 gtcgcacctg ccgccgcccg agccgatcga cgcggcgcac gagctcgggg tgaccgaggg
    12781 gtactggcgc gggtgggtgt cggcgtgcac gtaccagggc gagtggcgcg aggccgtggt
    12841 ccgctcgctg ctcaccctca aggcgctgac ctacggtccc accggcggca tcgtcgcggc
    12901 cgccaccacc agcctgccgg agaagctcgg cggcgtgcgc aactgggact accgcttctg
    12961 ctggctgcgc gacgccacca tcaccctgca ggcgctgctc tactccggct tccagagcga
    13021 ggccatcgcc tggcgcaggt ggctgctgcg cgccatcgcc ggcaaccccg ccgagctgca
    13081 gatcatgtac ggcgtcgccg gtgagcgccg cctcgacgag taccgcgcca cctggctggc
    13141 cggttatgac ggcaacccgg tccggatcgg caacgccgcc gccgagcagt tccagctcga
    13201 cgtctacggc gaggtgatgg acgccctgca ccagggccgc cgggccgggc tgacagccga
    13261 cgacccggcc tggggcctgc aggtcaagct gatggagttc gtcgagaacc actggcggga
    13321 gccggacgag ggcatctggg aggtgcgcgg cggcccgaag cagttcaccc actccaaact
    13381 gatggcctgg gtggcggccg accgcgcggt caaggcgatc gaggagttcg gcctgcccgg
    13441 gccccgggac cggtggaccc ggctgcgcga cgacatccgc gccgacatcc tcaagaaggg
    13501 ctacgacccg cggcgcgcca cgttcaccca gttctacggc tccgtggaac tggatgccgc
    13561 gatgctgatg gtcccgctgg tcggcttcct gcccgccgat gacgagcggg tccgcggcac
    13621 cgtcgcggcg atcgaggaac acctgctcgt cgacggtttc gtgcagcggt acacgcagca
    13681 cccggacagc ggcgtggacg ggctgccgcc gggcgagggc gcgttcctgg cctgcacgtt
    13741 ctggctcgcc gacaactacg ccctgatggg ccggcacgac gaggcccgcg agacgttcca
    13801 ccgcctgctg gccctgcgca acgacgtggg cctgctctcc gaggagtacg acacccgggc
    13861 cggccggctg gtcggcaact tcccgcaggc gttcagccac gtcccgctga tcgacacggc
    13921 ccggaccctg accagcgcgc tcgcgccgac cgaggcccgc gccgaggagg ggctgcgcta
    13981 gatccgccgg gcgcggccgg gcgccggatc gcgtgcggag tcgttcatca tccggtcgta
    14041 acgtggggtg ccatgcagac gagaaaactg ggggacctca cggtctcgac gatcggcttc
    14101 ggggcgatgg ggatgagcca cggctacggg ccgggcccgg accgggacgc gaacatcgcg
    14161 ctgctgcggg ccgcggtcga gcggggggtc accctcttcg acaccgccga ggtgtacggg
    14221 ccgtgggtca acgaggagct ggtcggcgag gcgctggagc cgttccgcgg ccaggtggtg
    14281 atcgccacca agttcggttt cgcgatcggc gcggacggcc gggagagcgg ggtggacagc
    14341 cgcccggaga acatccggcg ggtcgccgac gcctccctcc ggcggctgcg ggtggacgcc
    14401 atcgacctgt tctaccagca ccgggtcgac cccgacgtgc cgatcgagga ggtggccggg
    14461 acggtccggg agctgatcga ggccggcaag gtacgccact tcgggatgtc cgaggcggcc
    14521 cccgcgacga tccggcgggc gcacgcggtg cagccggtca ccgccgtgca gagcgagtac
    14581 tcgctgtggt ggcggcggcc ggaggaggga ctgctggaca ccctcgccga gctgggcatc
    14641 gggttcgtgc cgttcagccc gctcggccgc ggcttcctga ccggcacgat cggcgcggac
    14701 acggtgttcg cggacaacga catgcgcacc gggctgccgc ggttctccgc cgaggcgcgg
    14761 gcggccaacc aggcgctggt cgagctgatc gggcggatcg cggcgggcaa gggggcgacc
    14821 ccggcgcagg tggcgctggc ctggctgctg gcgcagcggc cgtggatcgt gccgatcccg
    14881 ggcacccggc ggccggagcg gctggcggag aacctgggcg ccacggaact cgcgctgagc
    14941 gccgccgacc tcgcggagat cgagtcggcg gcggcgcgga tcgaggtgcg gggcgcgcgg
    15001 taccccgagc agatggagcg gatgaccaac ctctgaccgg ccacgccgaa ccacacccgc
    15061 gggcggcggg tggcgaatct cccacccgct cgcccgatcg tggtgcattt cgtccttgga
    15121 accggcggac cgcccggcga acatgggacc atgcccgatc tcgacgtgct gatcgtcggc
    15181 gccggcctgt ccggcatcgg cgccgcctac tacctgcagc gtgaccatcc gcagcgcagc
    15241 tacgcgatcg tcgaggcacg cggcgccagc ggcggcacct gggacctgtt ccgctacccg
    15301 ggcatccggt ccgattccga cctgcacacc ttcggctacg agttccggcc gtggcgcgag
    15361 gaacgggtga tcgccgacgc cgcgtcgatc ctgcgctacc tgcgggagac cgccgcggag
    15421 cacggcatcg accggcggat ccgctaccac caccgggtga tcggcgcgtc ctggtccagc
    15481 ccggaggcga cctggcgggt ggcgatcgag cacaccgaca ccggcgagcg ctccgagatc
    15541 acctgccggt ggctgttctg cgccggcggc tactaccgct acgacgaggg cttcaccccg
    15601 gacttcccgg gacgcgacgg cttccgcggc acgatcgtgc acccccagca gtggccggac
    15661 gatctggacc acaccggccg gcgggtggcc gtgatcggca gcggcgcgac cgcggtcacc
    15721 ctggtcccgg cgctggccga gaccgccgcg cacgtcacga tggtgcagcg caccccgagc
    15781 tacgtggtgg ccgcgccggc ccgggacccg ctcgcgcccc ggctgcggcg gctgctcggc
    15841 gacgagcggg cgttcgccgt gatccgccgt aagaacatcg cccagcagcg ggcgatctgg
    15901 cagttctgcc agcggcaccc gaaggcggcg cgccgggtga tccggtggct gaacacccgc
    15961 caactgcccg cgggctatcc cgtggacgag cacttcaacc cgccgtacga cccgtgggac
    16021 cagcggctgt gcgtggtccc ggacggcgac ctgttccgcg cgatccggtc cgggaaggca
    16081 tccgtggtga ccgggcggat cgacacgttc accgccgacg gcgtgcggat ggcggacggg
    16141 cgactcgtcg aggccgacgt catcgtgacc gccaccgggt tgaacgtgca ggccttcggc
    16201 ggggtcgaac tcaccgtgga cggcgagccg gtgaagctgc cggagaccgt cgcctacaag
    16261 gggatgatgc tgtccggagt gccgaacctg gcgtacgcca tcggctacac caactcctcg
    16321 tggaccctca agatcggcct gctctgcgag cacttctgcc ggctgctgga gcacatggac
    16381 cggcacgggc acacggtgtg ccgcccgcgg ccggccgggc cgatggcgac ccggccgttc
    16441 ctggacttcg gggccggcta catccagcgg gcgctcgggc agctgccccg gcagggcgcg
    16501 cgggcgccgt ggctgacgtc gatgaactac cagtccgacg tgaagatgct gcgggaggcg
    16561 ccggtgaccg acccggagct gtcgttcgac taggtcgtcc accggccgtc atcgagcacc
    16621 gccacgccgt accacctcag caacgccagc cgtcacgaaa cgcggcctag gccgcgtttc
    16681 gtaaaggtca tcagagccat tggttgatga cggcgatggt gacggtggct tcgaagcgga
    16741 cggcaagctt gtcgtaccgg gtggccatcg cccggttctg tttgagctgg ttgatgccgc
    16801 attccacggc gtgacgctgc cggtacacga ccgggtcgaa cgccggagga cgcccgccct
    16861 tggagccttt ggccttgcgg taggcgtcct ggtcggcctt gctcgggatg cacaccctga
    16921 tcctgcggcg gcgggcgtac ccgcgattgc cccggctggt gtacgccttg tccgccagga
    16981 ccagatccgg ccgggtacgg ggccggccac caccgacccg atagaccttg atgcgttcca
    17041 ggaccttgat gaactgcgga ctgtcacccc gctgaccagc ggtgatcacc gtcgacagcg
    17101 tcttacgacc ctgctcacag gccagatggg tcttggtggt gaacccgccc cgggacctgc
    17161 ccagagcatg atcgccgggt tcggcgaaca ccccacccgg cggttccttc tgcaggtcac
    17221 catcacgacg ggcacccgcg gcatgctgat gggcacggct gatcgtggaa tcgacgctca
    17281 ccgcccactc gatgtcaccg gcggcgtcgg cccgggtctg gagccgggcc aggatcttcg
    17341 cccacgtccc gtcgcgctgc cagcgccgga accagcgata caacgtctgc cagggtgcgt
    17401 acacctcggg cacgtcccgc cacggtgttc ccgcccggac ccgccaccgg atcccatcga
    17461 tgatctgccg tttcgtccat cgcggcggac ggcctcgccg tggctccgca ggcagcgcag
    17521 gttccagcac cgcccactga acgtcggtga gatcgtgtcg cctcgctgcc gctaccctgg
    17581 gcacgaggtc tccggtggtt caggtttgct tggtcgctaa cccgtttacc ggagacctca
    17641 cttcgtatcg acaaccgcca cgccgggaca cgtcacacct cgcccgcact tacgaaacgc
    17701 ggcctagcgc cccgacccat aattgatcat cacgtaccgc agggagaaca tcagggccgc
    17761 gagggtgcgg aacgtctggc ccaggacggt gatggtgtag ttggacggta cgtcgccccg
    17821 ggtcacgcga tgaatgaagg tggacacccg atcccagtcg ttctccagct gggcatagtc
    17881 cgcaccgatc ggggtcgtgg tgtagtgcag cagattgtcg tagacgcggt tcaggatcaa
    17941 tccgaagcgg gccgcctcgg aaatgtactg aatggcgtcg acataggact gctgccgctg
    18001 ctgcagcgtg cggctgcccg ggtcgtacag cccgaggatc gagttgtaca tgccttccgg
    18061 cgtgaagacc cggctggcgc gagcctgctg ggaaccgccg ttgaggttgg tgtacgagcc
    18121 ggtgccgatg ttgctgaaca ccgccccggg cgccaccgag cgaatacgtt gccggaagac
    18181 gtcggaatag gtggagaact cgtagtggat attggtccgc tgcgaccaga acccggcgac
    18241 gtagaggatg ttcgaccaca ggtagacggt ggctatgtga tcaccgtcca ggacgatgtt
    18301 gatgccgatc agttgcgcgc cctggctggt ggtctcgtcg acgttgctct cgctctgata
    18361 gtcgtggccg gcggcccggt gaacggccgc gatcatgttg tagtaatccg tggcggcctc
    18421 cgcgccaccc caacgtaaat tgtcgatgtt ccaggtgatg ttgtagaagt tccccgacac
    18481 gtccgcggac gcgggcgtgg gcgagaccgc gagtgccgcg atggcggaca ccagtgccag
    18541 cactcctgac atgatgcggc gccacggccg gctcccgcgt gaaggatttc gtcgcacagc
    18601 tgcacacctc tccggttcca ttccgtcgag cagctccgtg cgagcagagc tgccggtcgg
    18661 cgacgagccg acgctgtgca gcctctcaag ccatcgtcag atggagatcc gtcaaatgac
    18721 tgcattcgcc gcgccgggcc ccgtccggcc gccgggcggg ggtgagccag gcggccgccg
    18781 gcatgggcgt gctgatcctc gaagaacacg acggcggtcc gggcagcccc tgagctgcgg
    18841 cgcggacgcc ggtcaggagg ccgcggcgcg gcggccgacg tactccgacc tctcctcgta
    18901 ctgctcggtc cagcggcggc tgctcgactc cagcgggtcc gactcgtgga ccgagcggcc
    18961 gtggaagcgc tgggcgtagt cgagcatccc gtcgacgagc cggtccacgt ccgcgcccgg
    19021 gcgtaccacc aggcgcatga actggctggt catgcccagc ttgttgccac actcgcgggt
    19081 catgatgccg tggttggcca ccaggaagtc gcgcagcgcc acgccggacc actcgttcgg
    19141 cagcttcacc aggaagaagt tgccctgcga ggggaacacc gtgagacccg ggatgcgctg
    19201 caactcccgg cccatcgacc ggcggtcgcg gctgagcagg cgcaggctct cctcgtactc
    19261 catctcgtgg tcctggatca tgtggaccac cttctcggcc agcgagttca ggttccactt
    19321 cggcagcatc ttcgcgatcc tgccggcgat ggccgggttg gccagcaggt agccgaaccg
    19381 gatgccgtgc aggccgaagt tcttgccgag cgacttgagc accaccgcgt tcgggcggat
    19441 caccgcgtcc gggccgaccg aggggtagcg ctcggcgtcg gagaagtcga tgaacgactc
    19501 gtcgaccacc accaggtcca ggtcgctgag cgcgtccagg aaccggatca cgtcccggcg
    19561 cggcaggtag ttgccgtccg ggttgttcac gttgcagatc accgcgaccc gggaccggcg
    19621 ctcccggatg aactcgacgt actcctccag gtccagccgg aagccgtcgc gctcctgcag
    19681 cggaaacatg tcgacccgtt tgccggtctc cagcggctgg tcggtccacc ggccgaaggt
    19741 cgggatcggg atggccaggc tctccttgac cagtagatgg tcgatccagg tgatcagctc
    19801 ggtggagccg ttcgccatcg ccaccgtctg cgggtgcagg cccagcacgg cggccagctt
    19861 cttggtgatg gtggccgagt cgctcgggta gtacttcagg atgctcttca gctcccgggt
    19921 cagctcgtcg aacatctccg gggtggggaa gtacgggttg cacggaatgc agaagtcgac
    19981 gatctccgcg ccgtccccgg ccgcccgggc gaggtcgaag taggacgcgc tgtgcgctcc
    20041 cctgtgcagg atcgacgtgt cgaatgcggt ccgtgccacg ctgtcctccc gatgccctga
    20101 agtgacgttg ccgccaccgg gtacgcggta cgcagcccga tcgttcacac catcgttgat
    20161 ccggtagagg cttaagcccg aggaaaggaa cgacatgcgg gggattctgc gtaccggact
    20221 gatcggtttc gtggtgctcg ggtcggtgac cgtcgcggac gaggcgcggg ccacgccggg
    20281 ggccggggtc gccgcccgga cggtggggca gcgggcggtg cacggcgccg gtcccgcccg
    20341 gcacgagtgg gccgcggcgc cgggcggcac ggtgtccacg agggagcgct gacccaccgg
    20401 gcttcgtaac ggccggtgtg ccgtctcccc tgttaccgtg accggggacc gggcgcctgc
    20461 gggaggagac acacgatgac cggctggccg gccgctccgg tgatctacga gatcgacacc
    20521 tggccgtggc tgaccgggct ggcccgccgt ctgggccggg aggtgaccct ggccgacgtg
    20581 cccgcggagg tctgggacga ggtggcggtg cccggcctgg acgcggtgtg gctgatgggt
    20641 gtctgggagc gcagcccggc ggggctggcc gtggcggagg cggacgacgg cctgcggcag
    20701 gcgttccggt acgcgctgag cgacctgaca ccggccgacg tggtcggctc gccgtactgc
    20761 gtgcgccgct accgcgccga cgaccgcctc ggcgggccgg ccggtctcgc cgccgcccgc
    20821 gagcagctgc gcgcccgtgg gctgcggctg gtgctcgact tcgtgccgaa ccacgtggcc
    20881 ccggaccacc cggcggtgac ccggcacccc gactggttcg tccagggcac cgaggaggat
    20941 ctggccggtg acccggccgg ctggttccgc gccggtggcc gggtgatcgc ccagggccgg
    21001 gacccgtact tcccgccgtg gccggacgtc gcccagctga acgcgttctc ggccgggatg
    21061 cgcgacgcga cgctggccgc gatgtcccag atcgcgcagc agtgcgacgg gatgcgctgc
    21121 gacatggcga tgctgctgac caacgagatc ttcgccggca cctggggccg gtgggccgga
    21181 ccggcgccgg cggcggagtt ctggccggag ctgatcggcc ggctgcgtga gcggcacccc
    21241 gg
//
