LOCUS       NZ_CP033073            25815 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces dangxiongensis strain Z022 chromosome, complete genome.
ACCESSION   NZ_CP033073
VERSION     NZ_CP033073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces dangxiongensis
  ORGANISM  Streptomyces dangxiongensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     The genome of Streptomyces dangxiongensis Z022
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) State Key Laboratory of Cryospheric
            Sciences, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. version 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 213.0x
            Sequencing Technology             :: Illumina and Pacpio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003675325.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 04:16:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,241
            CDSs (total)                      :: 7,151
            Genes (coding)                    :: 6,614
            CDSs (with protein)               :: 6,614
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 537
            CDSs (without protein)            :: 537
            Pseudo Genes (ambiguous residues) :: 0 of 537
            Pseudo Genes (frameshifted)       :: 320 of 537
            Pseudo Genes (incomplete)         :: 281 of 537
            Pseudo Genes (internal stop)      :: 26 of 537
            Pseudo Genes (multiple problems)  :: 83 of 537
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:47:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7354564
            Orig. end                         :: 7380379
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033073.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Binglin Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25815
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="melanin"
                     /product="terpene-precursor"
                     /region_number="31"
                     /rules="melC"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..25815
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="neighbouring"
                     /product="melanin"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10387
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10387
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5387](-)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5387)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="1"
     gene            complement(333..1223)
                     /locus_tag="D9753_RS33105"
                     /old_locus_tag="D9753_33095"
     CDS             complement(333..1223)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987937.1"
                     /locus_tag="D9753_RS33105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33095"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_121790345.1"
                     /transl_table=11
                     /translation="MKTAAGIRSQAEVAERTEQDRTGEGSLPGIAAPGSVAPRDARELS
                     RQFFRRLAELEEGTHEYQYARNTLIEMNMSLVRFAAGRFRSRGDDMDDIVQTGMIGLIK
                     AIDRFELSREVEFTSFALPYIVGEIKRFFRDTTWAVHVPRRLQELRVELAKAREELSSR
                     LDRDPTVAELATLMNISRAEVVEAQIASNGYNTASLDAALTGDGPEDGEAVLADFIGVE
                     EEGLRLVEDFHALAPLMAELSDRDRQILHMRFVEEATQAEIGERLGCSQMHVSRLIKRI
                     IARLRQGMLGELGCA"
     gene            1503..1970
                     /locus_tag="D9753_RS33110"
                     /old_locus_tag="D9753_33100"
     CDS             1503..1970
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433237.1"
                     /locus_tag="D9753_RS33110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33100"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_121790346.1"
                     /transl_table=11
                     /translation="MSSQVSEEAREAPGRPVPAPTDAPQPAPTEGPQPAPREPLWRELV
                     GAVLRRERRAQRRTLRQVADVARISLPYLSEIERGRKEASSEVLAAAARALGLGLGDLL
                     SLVHGELVRSAPPHGEPALRSASRPLSAARRRPVAAPNRSHLSHRGLCLAA"
     gene            2044..2526
                     /locus_tag="D9753_RS33115"
                     /old_locus_tag="D9753_33105"
     CDS             2044..2526
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004991876.1"
                     /locus_tag="D9753_RS33115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33105"
                     /product="VOC family protein"
                     /protein_id="WP_121790347.1"
                     /transl_table=11
                     /translation="MTTDGFVTCLWFDGRAEEAAHHYVSVFENSGVGRVVRHTEAGPGT
                     AGSVLTVEFTANGQKFLALNGGPEFRFNEAVSFQILCSDQQEIDHYWTKLTENGGEGGP
                     CGWLKDRYGVSWQVVYARLLDMIGDPDPEKAARATRAMMAMGKLDAAALEKAYAGE"
     misc_feature    2051..2066
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            2616..3410
                     /locus_tag="D9753_RS33120"
                     /old_locus_tag="D9753_33110"
     CDS             2616..3410
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670773.1"
                     /locus_tag="D9753_RS33120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33110"
                     /product="VOC family protein"
                     /protein_id="WP_121790348.1"
                     /transl_table=11
                     /translation="MAVQPEGTPCWADAMFSDIEGAKRFYADVLGWTFGESSSKYGNYT
                     QAYADGRAVAAVVPPMPGQEGRSQWCLYLASPDAAATAERIRDNGGEVLMGPMQVGDLG
                     TLCLGREPSGAVFGVWQAGRHEGFEATATPGAYCWAEVFTREPERSDAFLSAVFPYRMK
                     EIDDEAVDFRMFEVGEDTVLGRMRMTDDFPPEVPSYINVYFTVDHCDAAVARATALGAT
                     LRFGPMTSPFGRFAALTDPQGANFSVIDVTTTEGGMPRIRDV"
     gene            3445..4143
                     /locus_tag="D9753_RS33125"
                     /old_locus_tag="D9753_33115"
     CDS             3445..4143
                     /EC_number="3.1.26.4"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004523 - RNA-DNA hybrid ribonuclease
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446672.1"
                     /locus_tag="D9753_RS33125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33115"
                     /product="ribonuclease H"
                     /protein_id="WP_121790349.1"
                     /transl_table=11
                     /translation="MIVCMRERVVAACDGASKGNPGPAGWAWVISDDDERTPVGWAAGP
                     LGRATNNVAELTALERLLTAVDPDVPLEIRMDSQYAMKAVTTWLPGWKRNGWKTAAGKP
                     VANQDLVVRIDELLGGRSVEFRYVPAHQADGDPLNDFADRAASQAAVVQEPAGSELGSP
                     EPPPSPDTPVAAGAPRRKTPRRTGGAVSARTIKAKFPGRCPCGRSYAAGEKIAKNAQGW
                     GHPECRTAGS"
     misc_feature    complement(3451..3466)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.13"
                     /tool="antismash"
     gene            complement(4144..4965)
                     /locus_tag="D9753_RS33130"
                     /old_locus_tag="D9753_33120"
     CDS             complement(4144..4965)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003987919.1"
                     /locus_tag="D9753_RS33130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33120"
                     /product="tyrosinase family protein"
                     /protein_id="WP_121790350.1"
                     /transl_table=11
                     /translation="MTVRKNQAALTADEKRRFVAAVLELKRSGRYDDFVRTHNEFIMAD
                     TDSGERTGHRSPSFLPWHRRFLLDFEQALQAVDSTVALPYWDWSTDRTVRASLWAPDFL
                     GGTGRSTDGRVTDGPFAASAGNWPVNVRVDGRTFLRRSLGTSVSELPTRPEVESVLSMA
                     TYDMAPYNSASDGFRNHLEGWRGVNLHNRVHRWVGGHMATGVSPNDPVFWLHHAYVDKL
                     WAEWQRRHPGVGYVPTGGTPDVVDLDDTMKPWNTVRPADMLDHTAFYTFDA"
     cand_cluster    4790..25815
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    4790..25815
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[14789:15815](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(14790..15815)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="2"
     gene            complement(5001..5387)
                     /locus_tag="D9753_RS33135"
                     /old_locus_tag="D9753_33125"
     CDS             complement(5001..5387)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138613.1"
                     /locus_tag="D9753_RS33135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33125"
                     /product="tyrosinase cofactor"
                     /protein_id="WP_121790351.1"
                     /sec_met_domain="melC (E-value: 4.6e-50, bitscore: 168.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGITRRRALTAAAAVATTAAAATLAAPAASAASAAGRHEPAAPE
                     SFDEVYKGRRIQGRPSSGGGHHHEHGGGYAVFVDGVQLHVMRNADGSWISVVSHYAPVA
                     TPRAAARAAVDELQGAALLPFPAN"
     gene            5720..6922
                     /locus_tag="D9753_RS33140"
                     /old_locus_tag="D9753_33130"
     CDS             5720..6922
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670771.1"
                     /locus_tag="D9753_RS33140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33130"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_121790352.1"
                     /transl_table=11
                     /translation="MHVKVVCVGGGPAGLYLAILLKRQNPSHDITVHERDPEGSTYGWG
                     VTYWRGLLDRLQEHDPESARAVEEHSVRWNEGVAHVRDLAARHHGDEGFGIGRHRLLEL
                     LAGRARALGVRLEYRSDIGEPPAGADLVVAADGVHSALRTRRAEHFGTRTSSGRNHYIW
                     LGTTKVFDAFTFAFTETAHGWIWAYGYGYGDGHSTCVVECSPETFTGLGLDRADRAEGL
                     VLLEKLFAGVLDGHPLIARPGASWLTFRTLTNRTWHHGNLVLLGDAAHTTHYSIGAGTT
                     LALEDAMCLAGALREHAALPDALAAYERRRQAELLSVQSAARYSAQWYENLPRYIHLPP
                     HRMFALLGQRHSPLLPYVPPQLYYGLDRAAGRLEALRRLKRWLGPRAARALHARSTARR
                     D"
     misc_feature    complement(6977..6990)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.19"
                     /tool="antismash"
     gene            7046..>7447
                     /locus_tag="D9753_RS33145"
                     /old_locus_tag="D9753_33135"
                     /pseudo=""
     CDS             7046..>7447
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670769.1"
                     /locus_tag="D9753_RS33145"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33135"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDRPAAIPLPPGTGTPPRPRDRFAIPVLASGGILMAVMQTVVVPL
                     LPDLPRLTGSSPAAVSWMVTATLLSGAVLTPVLGLPLAALVVQYAGWHTMFWLTSALGA
                     LGVTATWRAVRESPVRETAADTVADRYGLA"
     gene            7574..8557
                     /locus_tag="D9753_RS33150"
                     /old_locus_tag="D9753_33140"
     CDS             7574..8557
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433219.1"
                     /locus_tag="D9753_RS33150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33140"
                     /product="aldo/keto reductase"
                     /protein_id="WP_121790353.1"
                     /transl_table=11
                     /translation="MDERVIGRSGQWASVIGLGTWQLGADWGDVDDKEALSVLEAAAES
                     GVTFFDTADVYGDGRSEETIASFLRGRPDLHVLVATKMGRRVGQLPENYVLDNFRAWND
                     RSRRNLGVDRIDLIQLHCPPTPVYSSEAVFDALDTLVEEERVAAYGVSVETCAEALTAI
                     ARPNVASVQIILNPFRMKPLYEVLPAAREAGVGIIARVPLASGLLSGKYTRDTVFAAND
                     HRSFNRHGEAFDQGETFSGVDYATGVEAAAEFAGLAPEGYTPAQLALRWIIEQEGVTTV
                     IPGARNPEQARANAAAAKLPPLPPETSTAIRELYERRISDQVEHHW"
     misc_feature    8581..8596
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.31"
                     /tool="antismash"
     gene            8610..9104
                     /locus_tag="D9753_RS33155"
                     /old_locus_tag="D9753_33145"
     CDS             8610..9104
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670766.1"
                     /locus_tag="D9753_RS33155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33145"
                     /product="DUF6328 family protein"
                     /protein_id="WP_121791420.1"
                     /transl_table=11
                     /translation="MTEAARRTGRDETEEEQADRKWGELIQEVRVAQTGVQILFGFLLT
                     VVFQPKYVRLTDTNQVIYIVTVVLGACATGALIGPVSLHRLVSGRRVKPQAVRLASRLT
                     FVGLVLLLATMTSSLLLILRVATHDGYVPYLVSGVVAWYLVCWYGLPLWARRKHTDRSD
                     D"
     gene            complement(9120..9686)
                     /locus_tag="D9753_RS33160"
                     /old_locus_tag="D9753_33150"
     CDS             complement(9120..9686)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037339.1"
                     /locus_tag="D9753_RS33160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33150"
                     /product="DinB family protein"
                     /protein_id="WP_121790354.1"
                     /transl_table=11
                     /translation="MRAMSDRPARWTRATVYPDMWADPADDPRDNGAAPEGEPATLSDF
                     LTNYRITLRMKCEDLDPEQLARRSVPPSTMSLLGLLRHLAEVERDWRNWITESDPLPKL
                     YGDGDADFEGAVAEQAAVDAAYADLEREQAATDAVLAGLPDLGERVGRERIAVRELMVH
                     RIEEYARHCGHADLLRECVDGRVGQ"
     gene            complement(9726..10322)
                     /locus_tag="D9753_RS33165"
                     /old_locus_tag="D9753_33155"
     CDS             complement(9726..10322)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670765.1"
                     /locus_tag="D9753_RS33165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33155"
                     /product="DUF2238 domain-containing protein"
                     /protein_id="WP_121791421.1"
                     /transl_table=11
                     /translation="MPPALLAAVAAGGLAASAWGARDRATWFLETVWALAGLPLVVLTR
                     RRFPLTGLLYGLLTAHALVLAVGGHYTYAQVPVGDWVRDAFGLDRNPYDRFGHLMQGFV
                     PAGRAGRELLSRTSPLRGSRWLAPLTVCACLAFSACFELLEWLAAEVGGHGADAFLATQ
                     GDVWDTQWDMCCALIGSVLSLLLLSRVHDRQLRAL"
     gene            complement(10439..10867)
                     /locus_tag="D9753_RS33170"
                     /old_locus_tag="D9753_33160"
     CDS             complement(10439..10867)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670764.1"
                     /locus_tag="D9753_RS33170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33160"
                     /product="SsgA family sporulation/cell division regulator"
                     /protein_id="WP_121790355.1"
                     /transl_table=11
                     /translation="MNPFVHKTLVVQLLAHGTGRCPVLAHLSYDADDPFAVTAVFAHDG
                     HVLASWRLDRQMLSDGLAGPVGVGDVRMRPEATGLWHELRLEFLGDVRPDGGRHHAVVF
                     AWAPAIASFLRETYQVLPPGQERVRVDELLEEILSAAE"
     gene            complement(10995..11966)
                     /locus_tag="D9753_RS33175"
                     /old_locus_tag="D9753_33165"
     CDS             complement(10995..11966)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020138623.1"
                     /locus_tag="D9753_RS33175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33165"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_121790356.1"
                     /transl_table=11
                     /translation="MVQIGYTMMTEQAGPRDLVNHLVQAEEAGFDFSVTSDHYFPWLRS
                     QGHASYAWSVLGAAAQATSRIPLMTYVTCPILRYHPAIVAQKAATVQLLSEGRFRLGLG
                     AGENLNEHVVGGGWPPVDVRHEMLEEAVQIIRALFEGGHVTHHGQHYDVESARLWDLPQ
                     EAPPIGLAVSGEQSCRLAGHLADLVIATEPKPGLLEAFDRHGGSGKPRVGQLPVCFDTD
                     RERAVKRAHSQFRWFGLGWKVNAELPHPDSFEAATQFVTEDDVASAIPCGDDPEAFVEA
                     VRPYVEAGFGEVALVQIGGDSQQEFIDWSAKTLLPALREAFA"
     misc_feature    complement(11941..11959)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.74"
                     /tool="antismash"
     misc_feature    complement(11957..11971)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.8"
                     /tool="antismash"
     gene            complement(12018..13577)
                     /locus_tag="D9753_RS33180"
                     /old_locus_tag="D9753_33170"
     CDS             complement(12018..13577)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003977.1"
                     /locus_tag="D9753_RS33180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33170"
                     /product="protein kinase"
                     /protein_id="WP_121790357.1"
                     /sec_met_domain="Pkinase (E-value: 5.1e-17, bitscore: 60.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMVEAHVSAHEWIAGRYRLLEVFARETNRLWWYAEDTAAGQPRL
                     VTQTALPEPVTEDTARRVTARVVRTGETMRLLCPGQVAAVVDAVVEAGTLWTVTEWIDG
                     TPLGELLAREGPFHPVRAARTGLDLLDVLRSAHDEGITHGELSPGQVFVRDGGPVVVTG
                     FGLAGATLVPRLTAPSYASPEQARDERVGPAADLWALGALLYTMVEGRPPFRDRGRPDA
                     TLKAVDRLPLRTPLRAGPLTRAVQGLLRKDARERLTRPVVRQALTRALTEDTDADHEPA
                     PTPRMRGASRFAAAGPRHGRRLLAVGAALAVAAVAAAVLAAAGALPGTDSAGPRRRATT
                     PAAPSDRHTGRAGTPVPTASASPALPPGYHRYTAPEGFSVALPDGWRRLTTSRVAGLAY
                     RVTFGRGGDSTTLAVTYSERVGPDPVAVWRDDVEPGLARLAGYHRVGAVRATTYQGRRA
                     ADLEWLTGSGRSRTHTFGRGFLLGGARGFSLRFTTPAGVWGNAAGRLALRTFLGTFRAP
                     KD"
     gene            complement(13737..14696)
                     /locus_tag="D9753_RS33185"
                     /old_locus_tag="D9753_33175"
     CDS             complement(13737..14696)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670761.1"
                     /locus_tag="D9753_RS33185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33175"
                     /product="threonine/serine dehydratase"
                     /protein_id="WP_121790358.1"
                     /sec_met_domain="PALP (E-value: 3.6e-71, bitscore: 238.7,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGISDIEAAAQRIAGHIVRTPTVASPGLGALLGVPVTAKLELLQ
                     RTGSFKARGATAKLLSLSAAERAAGVVAVSGGNHGVALAVMAAALDVKATVVMPRTAPA
                     RSLALAEDAGASVRLTDGMDSAFQLVTRLRDEGLTLVHPFDDPVVIAGQGTVGLELAED
                     AGELTDVVVSVGGGGLIAGVAAALRDRRPGVRVWGVETEGAEAMSGALKAGGPVPVPLS
                     SLVTTLSAPSVAQLTYDHVSALVEDVLVVPDRDAVRGCLDLADHAKVWAEPAAGCLLPA
                     ARQVAARAGAGARIGLVVCGGNTTPREIHGWAERFGLL"
     gene            complement(14790..15815)
                     /locus_tag="D9753_RS33190"
                     /old_locus_tag="D9753_33180"
     CDS             complement(14790..15815)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126220.1"
                     /locus_tag="D9753_RS33190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33180"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_121790359.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.4e-61, bitscore:
                     206.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALGSPVQDPALLTLTRCRKLVRPALEDAVGRLHPWMAEMAAYS
                     FGWCEVGGAPAAAPGGKGVRQALAVLGSEAAGADGRAGVPAAVAVELVHVFSLLHDDIM
                     DGDAVRRGRPTVWRAYGTGPAVLAGDALFALAVDVLAAAPEGPGAVRLLSSALADLVRG
                     QADDLLFATRPWTGPERVTAPEYRAMAEGKTGALLGCAAALGAALAGAPRAAVGALDRA
                     GRHLGVAFQLVDDVLGIWGDPAVTGKPVGGDLRERKKTYPVLAALGSPAARHLPALLDS
                     PGRAKEAAALVEAAGGRAAALAEARGHTAAARTLLADAPLAGGAARDLARLLDLLADRA
                     R"
     gene            complement(15812..16852)
                     /locus_tag="D9753_RS33195"
                     /old_locus_tag="D9753_33185"
     CDS             complement(15812..16852)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117960.1"
                     /locus_tag="D9753_RS33195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33185"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_121790360.1"
                     /transl_table=11
                     /translation="MYGKAFAPEYQGALTTLSVNSSLVDVLAEGTERLREAERAGLPGE
                     AARCGLAVAEAHRRLGHVRDADRAWKASYRAAREAGDTAAMAWALWSGGTLARQRGAFP
                     LARRLLKLAADLGERGGDVVVRGYSLAGLAETGRIQGDYAAVGRLHEQLLAEARSRGEA
                     RHTVWALEGIAQMHRNTGDLDRAYALFEEAAQIAGRADDRRGYAWALRGLADVLSVRDG
                     ATARALELLAEAEATCREMNLSSALAYNHKMQGNVLYRAGRHAEARDRYELALAEFRTM
                     SEPRGEALSRLGLAKSLAHLGRDRAETAAELAELARTLERSGLRHARETVARAQREFGL
                     DAEAAR"
     misc_feature    complement(16869..16887)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.62"
                     /tool="antismash"
     misc_feature    16871..16889
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.63"
                     /tool="antismash"
     gene            complement(17006..17683)
                     /locus_tag="D9753_RS33200"
                     /old_locus_tag="D9753_33190"
     CDS             complement(17006..17683)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433207.1"
                     /locus_tag="D9753_RS33200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33190"
                     /product="AIM24 family protein"
                     /protein_id="WP_121790361.1"
                     /transl_table=11
                     /translation="MKGDLFSSQHVVQPAVEPGMSVENAKCLRYAVNGEMYARQGAMVA
                     YRGGLKFERKGQGVGGMLKRAVTGEGLPLMAVRGQGEAWFAHEAQNCFIVEVEAGDRFT
                     VNGRNVLCFDASLSYEIKTVKGSGIAGGGLFNSVFSGQGRLGLVCDGNPLVIPVTAQAP
                     VYVDTDAVVGWTAHLETSLHRSQSLGSMLRGGSGEAVQLMLQGEGYVVVRPSELTPQKA
                     QQH"
     gene            complement(17759..18925)
                     /locus_tag="D9753_RS33205"
                     /old_locus_tag="D9753_33195"
     CDS             complement(17759..18925)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670753.1"
                     /locus_tag="D9753_RS33205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33195"
                     /product="serine hydrolase"
                     /protein_id="WP_121790362.1"
                     /transl_table=11
                     /translation="MVSATVVRGAVLGAVALSLLAVPARAVAGEHDTPAAAALPAPDTA
                     GLASVLRSVVAQGAPGALARIDDHGRTYRVTHGVADRSSARAISTEDRFRVGSITKTFS
                     AVVLLQLVDEHRLSLDAPVNRYLPKLLPDDRITVRQVLGHRSGLYDYTNDMFAHSVSGF
                     EAVRNKVFTYRQLVALSLKKPRTNAPGAAYAYSNTNFVVAGLLIEKLTGQPVATAYRNR
                     VIGPLGLGDTFYVHPSTAIPGRYARGYLTPDTAGAAPVDATAQTVSWAQSAGAVISSAR
                     DLDTFYGALLGGKLMSAARLAEMERFTPVNSTTAYGLGLRRRDLSCGISVYGHTGAVQG
                     YYTYAFATKDGGRSLTAMADTSNNGKVLDTLAGALDSAFCGKARTVEP"
     misc_feature    18958..18973
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     misc_feature    complement(19062..19076)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.08"
                     /tool="antismash"
     misc_feature    complement(19063..19078)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.79"
                     /tool="antismash"
     misc_feature    complement(19207..19216)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            19263..21023
                     /locus_tag="D9753_RS33210"
                     /old_locus_tag="D9753_33200"
     CDS             19263..21023
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015493184.1"
                     /locus_tag="D9753_RS33210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33200"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_121790363.1"
                     /transl_table=11
                     /translation="MAIAIAVTTAATGLAGTAFAGPSTGVERTAASAASNATVVVEAAR
                     TAAFTHASATGVSKGDALHAQDVLLDPEGARHVRFVRTHDGLPVLGGDLIVHLDRGLGY
                     TGVTRAADHTVKPAAEARLTPAQAAAKAAEAAKGDAGGVQLVLDARGGASALAYQVTVT
                     AGGNPHTVVVDAVTGKVRSNTPVRDEFLSPKLVDTLRERGESADPVTGSGSASGASGLL
                     GSGASGVTHYPSAAKGPGKTLFVGTVGLTTTQTSRGHFQLKDPNRYGTETRDAKGSETE
                     KFSAGTKFTNTTDVWGNGKTTSRVSAAADAQYGITKTLDFYKGTFGRKGIANNSKAAQA
                     MVHWGKKVGNAFWDPTCNCMLYGDGDGDMFKKPLVVLDVTGHELTHGVVEATANLQPTI
                     VDKYGNQYGEPGSLNESLADIFGSNVEFYAKNTKDTPDYLIGEKLGLAQKFLRRLDHPS
                     LDKLEGTIDYWKPEVYGTEVHAGSGVSSHAYYLLAEGSGKKTIGGVAYNSPTYHNLTVK
                     GIGRTKATAVYYRALTRYMVSDTDFHQARLATLKAAKDLYGANSTEYKTVDRSWSAVNV
                     TAANTPAARH"
     gene            complement(21126..21476)
                     /locus_tag="D9753_RS33215"
                     /old_locus_tag="D9753_33205"
     CDS             complement(21126..21476)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014670746.1"
                     /locus_tag="D9753_RS33215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33205"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_121790364.1"
                     /transl_table=11
                     /translation="MNDVEGIDPRVPPSGTGCVECEEAGGWWFHLRRCARCGHIGCCDD
                     SPGRHATAHYRETGHPVIRSFEPGEAWFWNFATEELYGSGPELAPPAGHPADQPAPGPA
                     GRVPADWAQTLR"
     gene            complement(21473..22924)
                     /locus_tag="D9753_RS33220"
                     /old_locus_tag="D9753_33210"
     CDS             complement(21473..22924)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117949.1"
                     /locus_tag="D9753_RS33220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33210"
                     /product="ATP-binding protein"
                     /protein_id="WP_121790365.1"
                     /transl_table=11
                     /translation="MSGQVMPCSPGEIGSLFLFEKLSGQQLGRLCGAGRVELFQAGPVY
                     TEGDPATCFFVMVEGTVVLSRRVGGDDVEVTRTSQPGVYAGAMQAYLGDRVPQVYNNSM
                     RVTEPTRFFVLPADLFAEVMREWFPMAVHLLEGLFFGSKNTQAMIGQRERLLALGSLSA
                     GLTHELNNPAAAAVRATSALRERVAKMRHKLGVIAGGPFSRDVLASLIEIQERTAERVA
                     KAPVLGPLEASDREDRLTDWLADHGFEQGWQVAPTFVQAGLDVDWLEQVAAAVDEEILP
                     NAVGWLNYTIETELLMSEIEDSTTRVSHLVDAAKQYAQLDRAPYREVDVHELLDSTLLM
                     LSGKIGPGIGVVKEYDRTLPPVPAYPAELNQVWTNLIDNAVSAVRSAGGEGTLTVRTAL
                     DHERLLVEFRDTGPGVPTEIRDRIFDPFFTTKPVGEGTGLGLDISWRIVVNKHHGTLRV
                     ESEPGDTRFQVLLPLTAETHDEEQE"
     gene            complement(22921..24597)
                     /locus_tag="D9753_RS33225"
                     /old_locus_tag="D9753_33215"
     CDS             complement(22921..24597)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010033203.1"
                     /locus_tag="D9753_RS33225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33215"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_121790366.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 5.1e-27, bitscore:
                     93.5, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQAADAARTVILTVDDDPGVSRAVARDLRRRYGASYRIVRAESG
                     ESALEALRELKLRGDLVAVILADYRMPQMNGIEFLEQALDVYPGARRVLLTAYADTDAA
                     IDAINVVDLDHYLLKPWDPPEEKLYPVLDDLLEAWRTRAYRPVPSTKIVGHRWSARSSD
                     VREFLARNQVPYRWYSVEEPEGRRLLAAAGQDGQRLPLVITPDGSALVEPEAPELAARV
                     GLATTPTSEFYDLVVIGGGPAGLGAAVYGASEGLRTVLVERSATGGQAGQSSRIENYLG
                     FPDGVSGAQLTDRARRQAARFGAEILTAREVTGLEACGAARVVRFADGSAIAAHSVILA
                     TGVQYRQLDAAGCTDLTGCGVFYGSALTEAASCQGQDVYIVGGANSAGQAAMYLSRGAK
                     SVTLLVRGPDLSASMSYYLIQQIGEAPNISVRCHTVVEEAHGSGRLERLTLRHMVTGET
                     EQVDAQWMFVFIGAAPLTDWLGEAVLRDGRGFILSGPDLTADGRPPAGWELDRPPYHLE
                     TSVPGVFVAGDARAESAKRVASAVGEGAMAVMLVHRYLEQS"
     misc_feature    complement(24664..24677)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.03"
                     /tool="antismash"
     gene            24818..25684
                     /locus_tag="D9753_RS33230"
                     /old_locus_tag="D9753_33220"
     CDS             24818..25684
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020117946.1"
                     /locus_tag="D9753_RS33230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_33220"
                     /product="universal stress protein"
                     /protein_id="WP_121790367.1"
                     /transl_table=11
                     /translation="MTRPITAGVDGTEESLAALDWAAREAVRRGLPLRVVHAWRYAETL
                     AAADRDTQHGWVSRGVSQAVRAAAGRHPDLTVSVDVVEDGAAQALAGAAADAEMLVLGS
                     RGHGPVVGFLLGSVGQQVIAEAARPVVLVRAEAETTAEAAGRDVVVGQDGAPEDSAAAL
                     RFAFETAAARGATVRAVRAWTLPPVFAYSPGSLRLLDDAGGLEPYERQSLAEALQPWRE
                     RFPEVPVAEHVEMGSAGHVLLSLTGRAQLVVVGRRAHRTAVGARIGSVAHGVLHHADCP
                     VAVVPHA"
ORIGIN
        1 agccgcgcgg acggcgagct gctcctggtg gtgagcgagc tggtgaccaa cgcggaccgg
       61 cacagccgcg gcccctacat cctggagctg gagggcacga agagcacggt ggccgtgtcc
      121 gtgtacgaca gcagcaccgc cctgccccgc cgctacccca aggaccccca gcgcgtcgga
      181 cggcacggtc tggagatcgt gcacgccctg gcctcggagg tcaccgtgga gcgcgtaccg
      241 gtgggcaagc gggtacgcgc ccgtttcgaa ctcgtacgct gacctcggca gcgctcgcgg
      301 tgcgggcgcc actgcctcgg atcagcggcg ggtcaggcgc agccgagttc gccgagcatc
      361 ccctggcgca gccgggcgat gatccgcttg atcagccggg agacgtgcat ctgggagcag
      421 ccgagccgct caccgatctc cgcctgggtg gcctcctcga cgaaccgcat gtggaggatc
      481 tgccggtcgc ggtcgctcag ctccgccatc agcggggcca gcgcgtggaa gtcctcgacg
      541 agccgcagcc cctcctcctc cacaccgatg aagtcggcga gcacggcctc gccgtcctcg
      601 gggccgtcac cggtgagcgc ggcgtccaga gaggcggtgt tgtagccgtt ggaggcgatc
      661 tgggcctcga cgacctcggc ccgggagatg ttcatcagcg tggccagttc ggcgaccgtg
      721 gggtcccggt ccagccggct ggacagctcc tcgcgtgcct tggccagttc cacccgcagt
      781 tcctggagcc gacgcgggac gtggaccgcc caggtggtgt cgcggaagaa ccgcttgatc
      841 tcccccacga tgtacggcag cgcgaaggag gtgaactcga cctcgcggga cagttcgaac
      901 cggtcgatgg ccttgatgag gccgatcatg ccggtctgca cgatgtcgtc catgtcgtcg
      961 ccgcggctgc ggaaccgtcc cgcggcgaac cgcaccagcg acatgttcat ctcgatgagg
     1021 gtgttgcgcg cgtactggta ctcgtgcgtg ccctcctcca gctcggcgag ccggcggaag
     1081 aactgacggg acagctcccg tgcgtcgcgc ggggcgacgg accccggagc cgcgatccca
     1141 ggcagtgatc cctcgcccgt cctgtcctgc tcggtcctct cggcgacctc tgcttgtgac
     1201 cggatcccgg cggcggtctt cattgcctct cccacgaaaa gtcaggtgcg acgtctgcct
     1261 tggcggcctc tgtgtgcccg agtcccgtcc atgaagatgt ggcagtgcgg gtacccggta
     1321 tccggagaat catgcgtacc tgcggaactc ttcaccctgc gggtacccat ggtgacccgg
     1381 cgcatgcacc cacccggccg taccggcctg aaacaaccgg tccgcccgcg tcggtcaggc
     1441 atttccctca gggcggaacg ccggaccctt gtccccggcc ggaccgctcc tacgctgacg
     1501 ggatgagcag ccaggtgagc gaagaggccc gcgaggcccc cgggcggccg gtacccgccc
     1561 cgacggacgc gccgcagccc gccccgacgg agggcccgca gcccgcgccg cgggagccgc
     1621 tgtggcgcga gctggtcggc gcggtgctgc gccgggagcg gcgggcccag cggcgcacgc
     1681 tcaggcaggt ggccgacgtg gcccggatct cgctgccgta cctgtccgag atcgagcgtg
     1741 gccgcaagga ggcctcctcc gaggtcctcg ccgccgcggc ccgcgcgctc ggcctggggc
     1801 tcggggacct gctgtcgctg gtccacggcg agctggtccg gagcgcgccg ccccacggag
     1861 agccggccct gcggtcggcc tcgcgccccc tgtcggccgc gcggcggcgg ccggtcgccg
     1921 cgccgaaccg gtcgcacctg tcgcaccgcg gcctctgtct cgcggcctga cgggcggccg
     1981 atgagtttcg cggcgtgcga cggtcggtac agatgaccgc gttccacgcc ccgggaggta
     2041 ctcatgacca ccgacggttt cgtcacgtgt ctctggttcg acggccgggc ggaggaggcc
     2101 gcgcaccact acgtgtccgt cttcgagaac tcgggtgtcg gacgcgtcgt gcgccacacc
     2161 gaggccgggc ccggcacggc cggctccgtg ctgaccgtgg agttcacggc caacggccag
     2221 aagttcctcg cgctcaacgg cgggcccgag ttccggttca acgaggcggt ctccttccag
     2281 atcctctgct ccgaccagca ggagatcgac cactactgga cgaagctcac cgagaacggc
     2341 ggcgagggcg gcccctgcgg ctggctcaag gaccggtacg gcgtctcctg gcaggtggtc
     2401 tacgcccggc tgctcgacat gatcggcgac ccggacccgg agaaggccgc gcgtgccacc
     2461 cgggccatga tggccatggg caagctggac gccgccgcgc tggagaaggc gtacgcgggg
     2521 gagtgaccgg ccccctgccg ggctcgacgc gcgggcccgg ccccgcatgg ttagcgtgaa
     2581 caaccgggac acaccacacc gggagggtcg ggaccatggc cgtgcagccc gagggaacgc
     2641 cctgttgggc cgatgcgatg ttcagtgaca tcgagggcgc caaacggttc tacgccgacg
     2701 tgctcggctg gaccttcggc gagtcgtcgt cgaagtacgg caactacacg caggcctacg
     2761 cggacggcag ggcggtggcc gccgtggtcc cgccgatgcc cggccaggag ggccggtcgc
     2821 agtggtgcct gtacctcgcc tcgccggacg ccgccgccac cgcggagcgg atccgggaca
     2881 acggcggcga ggtgctgatg gggccgatgc aggtcggcga cctgggcacg ctgtgtctgg
     2941 gccgggagcc cagcggggcc gtgttcggtg tgtggcaggc cggccggcac gagggcttcg
     3001 aggcgacggc cacgcccggc gcctactgct gggcggaggt cttcacccgg gaacccgagc
     3061 ggtcggacgc cttcctgtcc gccgtgttcc cgtaccggat gaaggagatc gacgacgagg
     3121 cggtggattt ccggatgttc gaggtcggtg aggacaccgt cctcggcagg atgcggatga
     3181 ccgacgactt cccgcccgag gtcccctcgt acatcaacgt ctacttcacc gtggaccact
     3241 gcgacgcggc cgtcgcccgg gccaccgcgc tcggcgccac cctccgcttc ggcccgatga
     3301 ccagcccctt cggccggttc gccgcgctca ccgacccgca gggcgccaac ttctcggtga
     3361 tcgacgtcac gaccaccgag ggcgggatgc cgaggatcag ggacgtctga cccggctccg
     3421 tccggccgcc tccccggtca tggcatgatc gtgtgcatgc gtgaacgtgt ggtggccgcg
     3481 tgcgacgggg cttcgaaggg caaccccgga ccggccggat gggcgtgggt catctcggac
     3541 gacgacgagc ggacccccgt cggctgggcg gcgggcccgc tcggccgggc caccaacaac
     3601 gtcgccgaac tgaccgccct ggagcggctg ctcacggccg tcgacccgga cgtgccgctg
     3661 gagatccgca tggactccca gtacgcgatg aaggccgtca ccacctggct gccgggctgg
     3721 aagcgcaacg gctggaagac cgccgccggc aagcccgtcg ccaaccagga cctggtcgtc
     3781 cgcatcgacg aactcctcgg cggccggtcc gtggagttcc gctacgtgcc cgcccaccag
     3841 gccgacggcg acccgctgaa cgacttcgcc gaccgcgcgg ccagccaggc ggccgtcgtg
     3901 caggaacccg ccggcagcga gctgggttcg ccggagcccc cgccgtcgcc ggacaccccg
     3961 gtggcggccg gtgcgccgcg ccggaagacg ccgcggcgca ccggcggcgc cgtgtccgcc
     4021 cgcaccatca aggcgaagtt ccccggccgc tgtccgtgcg gccggtccta cgcggccggc
     4081 gagaagatcg ccaagaacgc gcagggctgg ggccacccgg agtgccgtac cgccgggtcc
     4141 tgatcaggcg tcgaacgtgt agaacgcggt gtggtccagc atgtccgccg ggcgcacggt
     4201 gttccacggc ttcatggtgt cgtccaggtc caccacgtcc ggcgtgccgc ccgtcggcac
     4261 gtaaccgacg cccgggtggc gccgctgcca ctccgcccac agcttgtcga cgtaggcgtg
     4321 gtgcagccag aacaccgggt cgttggggga gaccccggtg gccatgtgcc cgccgaccca
     4381 gcggtggacc cggttgtgca ggttgacccc ccgccagcct tccaggtggt tgcggaagcc
     4441 gtccgatgcg ctgttgtacg gtgccatgtc gtacgtcgcc atggacagca ccgactcgac
     4501 ctcggggcgc gtcggcagct cgctcacgga cgtgccgagc gaacggcgca ggaaggtacg
     4561 gccgtccacc cgcacgttga ccggccagtt cccggcggac gcggcgaacg ggccgtccgt
     4621 cacccgcccg tcggtgctgc gcccggtgcc gccgaggaag tccggcgccc acagggaggc
     4681 ccgcaccgtg cggtcggtgc tccagtccca gtacggcagg gcgaccgtgg agtccacggc
     4741 ctggagcgcc tgctcgaagt cgagcaggaa tctgcggtgc cagggcagga aggagggcga
     4801 gcggtggccg gtccgctcgc ccgagtcggt gtccgccatg atgaactcgt tgtgcgtgcg
     4861 gacgaagtcg tcgtagcgtc cgctgcgctt cagttcgagg acggcggcga cgaaccgccg
     4921 cttctcgtcg gcggtcaggg cggcctggtt cttgcgtacc gtcatggtgc ggggtgctcc
     4981 gggattccgt gcgggggcgg tcagttggcg gggaacggca gcagcgcggc gccctggagc
     5041 tcgtccaccg cggcccgggc ggcggcgcgc ggggtggcca ccggggcgta gtggctgacg
     5101 acgctgatcc agctaccgtc ggcgttgcgc atcacgtgca actgcacgcc gtcgacgaac
     5161 accgcgtagc caccgccgtg ttcgtggtgg tgtccaccgc cgctcgacgg acggccctgt
     5221 attcggcggc ccttgtagac ctcgtcgaag gactcgggcg cggcgggctc gtggcggccg
     5281 gcggcggacg cggcggacgc ggcgggcgcg gcgagggtgg cggccgcggc cgtcgtggcg
     5341 acggcggctg cggcggtgag cgcacggcgc cgggtgatgc cgggcatgcg ggtcctcctc
     5401 gggagtggtg gagtgtgacg acgcatgcct atcgggcgtt acgggaaagg aggaaatcac
     5461 tcggaacggg ttggctgtga tccggacaat tagccacatg acgtacagag ttggaccaag
     5521 atgatcttgc tgtgaccggg tgtcgatccg ctgcggaacg gggaattcct tgccgggtcg
     5581 tcccgcttcc ccgtgatcct tcccgggggc cgcccgtccg agtggcgcgg ctcaccacac
     5641 caggctgacg cgatcgagcg ggtcgccggg actgctaccg tccggtgccg atcgaccacg
     5701 tccggtgaca gtcaggggtg tgcacgtgaa ggtcgtctgt gtcggaggcg ggcccgcggg
     5761 cctgtacctc gccatcctgc tcaagcggca gaacccgtcc cacgacatca ccgtccacga
     5821 acgcgacccc gagggctcca cctacggctg gggcgtgacg tactggcgcg gcctcctcga
     5881 cagactccag gagcacgacc ccgagtcggc gcgtgcggtc gaggagcact ccgtccgctg
     5941 gaacgagggt gtcgcccacg tccgggacct ggccgcccgc caccacgggg acgagggctt
     6001 cggcatcggc cggcaccggc tgctcgagct gctcgccggc cgggcccgcg ccctcggcgt
     6061 ccgcctggag taccggagcg acatcggtga accgcccgcc ggagccgacc tcgtcgtcgc
     6121 ggccgacggc gtgcacagcg ccctgcgcac ccggcgcgcc gagcacttcg gcacccggac
     6181 ctcctccggc cgcaaccact acatctggct cggcaccacc aaggtcttcg acgccttcac
     6241 cttcgccttc accgagaccg cgcacggctg gatctgggcc tacggctacg gctacggcga
     6301 cggccacagc acctgcgtcg tcgagtgctc cccggagacc ttcaccggcc tcggcctgga
     6361 ccgggcggac cgggccgagg gcctcgtgct gctggagaag ctcttcgccg gcgtcctcga
     6421 cggccacccc ctcatcgccc gccccggcgc ctcctggctg accttccgca ccctcaccaa
     6481 ccgcacctgg caccacggca acctcgtcct gctcggcgac gccgcccaca ccacccacta
     6541 ctccatcggc gccggcacca ccctcgccct ggaggacgcc atgtgcctgg ccggcgccct
     6601 gcgggagcac gccgccctgc ccgacgccct cgccgcctac gagcgccggc gccaggccga
     6661 gctgctgtcc gtgcagagcg cggcccgcta cagcgcccag tggtacgaga acctgccccg
     6721 ctacatccac ctgcccccgc accggatgtt cgccctgctc ggccagcgcc actcgcccct
     6781 gctgccgtac gtccccccgc agctctacta cgggctggac cgggccgccg gacggctgga
     6841 ggcgctgcgc cggctcaagc gctggctcgg cccccgcgcc gcccgtgccc tgcacgcccg
     6901 ctccacggcc cgccgggact gacccccgcc ggcccggcat cccgtcaccg gcgcacgtca
     6961 gggcggagga cgtcggtgaa tggccattca cccgatacgg tgaatcgctg ttcacctcgc
     7021 cgccgtgctg cccgcaggag ccccgatgga ccggcccgcc gccatacccc tgccgcccgg
     7081 caccggcacg ccgccccggc cgcgcgaccg gttcgccatc ccggtgctcg cgtcgggcgg
     7141 catcctcatg gcggtcatgc agaccgtggt cgtaccgctc ctgccggacc tgccccggct
     7201 caccggctcg tcaccggccg ccgtctcctg gatggtcacc gcgaccctgc tctccggcgc
     7261 cgtcctcacc cccgtcctcg gcctgccgct cgccgcgctg gtcgtgcagt acgccggctg
     7321 gcacacgatg ttctggctga ccagcgcgct cggtgcgctc ggcgtcacgg cgacctggcg
     7381 ggcggtcagg gagtcaccgg tgcgcgagac cgccgccgac accgtcgccg accgctacgg
     7441 gctcgccgta caggcccagc tcacgcccgg ccgctgagcc ggcgcggccc gccggccagg
     7501 gtcgtccgcg ccgcggtgtc ccgccggagc ggcccgttcc gcgggacgcc gtgccggatg
     7561 tcacactgac gccatggacg aacgcgtaat cggcaggtcg ggtcagtggg cgtcggtgat
     7621 cggtctcggc acatggcagc taggcgcgga ctggggcgac gtggacgaca aggaggccct
     7681 gtccgtcctg gaggcggcgg ccgagtcggg agtcacgttc ttcgacacgg ccgacgtgta
     7741 cggcgacggg cgcagcgagg agaccatcgc ctcgttcctg cgcggccgtc ccgacctgca
     7801 cgtgctggtg gccaccaaga tgggccgccg ggtcgggcag ctccccgaga actacgtcct
     7861 ggacaacttc cgcgcctgga acgaccgctc gcgccgcaac ctgggtgtcg accgcatcga
     7921 cctgatccag ttgcactgcc cgcccacccc ggtctactcc tccgaggcgg tgttcgacgc
     7981 cctggacacc ctggtcgagg aggagcgcgt cgccgcgtac ggggtgagcg tggagacctg
     8041 cgcggaggcg ctcaccgcga tcgcccggcc gaacgtggcg agcgtgcaga tcatcctcaa
     8101 cccgttccgt atgaagcccc tgtacgaggt gctgcccgcc gcccgcgagg ccggcgtcgg
     8161 catcatcgcg cgcgtgcccc tcgcctccgg gctgctgtcc ggcaagtaca cgcgggacac
     8221 ggtgttcgcg gccaacgacc accgctcctt caatcgccac ggcgaggcct tcgaccaggg
     8281 cgagaccttc tccggcgtcg actacgccac tggcgtggag gccgccgccg agttcgccgg
     8341 gctcgccccc gaggggtaca ccccggccca gttggcgctg cgctggatca tcgagcagga
     8401 gggcgtcacc acggtgatcc ccggcgcgcg caacccggag caggcccgcg ccaacgcggc
     8461 ggcggccaag ctgccgccgc tgccgcccga gacgtccacc gcgatccggg agctgtacga
     8521 gcgccggatc agcgaccagg tcgaacacca ctggtaggcc cccgtacgcg gaccgtttga
     8581 acgaacggct gtgcggttac acgcaccgca tgacggaggc agcacggcgt acaggccgcg
     8641 acgagaccga ggaggagcag gcggaccgga agtggggtga actcatccaa gaggtccggg
     8701 tggcgcagac cggcgtgcag atcctgttcg gcttcctgct gaccgtcgtc ttccagccga
     8761 agtacgtgcg gctcacggac acgaatcagg tcatctacat cgtgaccgtc gtcctgggcg
     8821 cctgcgcgac cggcgccctc atcggaccgg tctccctgca tcgcctggtc tccggccgcc
     8881 gggtcaagcc gcaggccgtg cggctggcct cccggctgac gttcgtcggc ctggtgctgc
     8941 tgctcgccac gatgacgtcg tcgctgctgc tgatcctccg ggtggccacg cacgacggct
     9001 acgtgcccta cctggtctcg ggcgtcgtcg cctggtacct cgtgtgctgg tacggcctgc
     9061 ccctgtgggc ccgccgcaag cacacggacc gctcggacga ctagggcccg cccggccggt
     9121 cactggccca cccgcccgtc gacgcactcg cgcagcaggt cggcgtggcc gcagtgccgg
     9181 gcgtactcct cgatcctgtg caccatcagc tcccggaccg cgatccgctc tcttcccacc
     9241 cgctccccga ggtccgggag cccggccagt acggcgtccg tcgcggcctg ctcgcgctcc
     9301 agatcggcgt acgcggcgtc gaccgcggcc tgttcggcga ccgctccctc gaagtccgcg
     9361 tccccgtcgc cgtacagctt cggcagcggg tcgctctcag tgatccagtt gcgccagtcg
     9421 cgttccacct cggcgaggtg cctgagcagg ccgaggagtg acatcgtcga cggcgggacc
     9481 gagcgccggg cgagctgctc ggggtccagg tcctcgcact tcatccgcag ggtgatgcgg
     9541 tagttcgtca ggaagtccga cagggtcgcc ggctcgccct ccggggcggc accgttgtcg
     9601 cgggggtcgt cggccgggtc ggcccacatg tcggggtaga cggtcgcccg ggtccatcgt
     9661 gcgggtcggt cgctcatggc tcgcatggtg gtccgcggcg gccccggtcc gccaccgaat
     9721 tgtcgtcaca gcgcgcggag ctgacggtcg tggacccggc tgagcagcag cagggacagc
     9781 acggacccga tcagcgcgca gcacatgtcc cactgggtgt cccacacgtc gccctgggtg
     9841 gcgaggaacg cgtccgcgcc gtgccccccg acctccgccg ccagccactc cagcagctcg
     9901 aaacaggcgc tgaacgccag gcaggcgcac acggtgagcg gggccagcca gcggctgccg
     9961 cgcaacggcg aggtgcggct gagcagttcc cgaccagcac ggccggccgg tacgaagccc
    10021 tgcatcagat gcccgaagcg gtcgtacggg ttgcggtcca ggccgaaggc gtcgcgcacc
    10081 cagtcgccca ccggtacctg cgcgtaggtg tagtgcccgc cgaccgcgag gaccagcgcg
    10141 tgcgcggtca gcagcccgta cagcagcccc gtcagcggga agcgccgccg ggtcagcacg
    10201 accaggggca gcccggccag cgcccacacc gtctccagga accaggtggc gcggtcgcgc
    10261 gcgccccacg cggacgccgc caggcccccc gccgccacgg cggcgaggag ggcgggcggc
    10321 acgcggcgcg gcgcgcggag cgggagggac ggtgctgcgg tcacggcggg ctccttgcct
    10381 gcggggcgtc gggggagccc atcgtggcgc cgggccggga ccgcggacat gagtacggct
    10441 actcagccgc ggagaggatc tcctccagca gttcgtccac ccggacgcgc tcctggcccg
    10501 gcgggaggac ctggtaggtc tcgcgcagga aggaggcgat cgcgggcgcc caggcgaaca
    10561 ccaccgcgtg gtgccggccg ccgtccggcc gcacgtcccc gaggaactcc agccgcagtt
    10621 cgtgccacag gccggtggcc tccggccgca tccgcacatc accgaccccg accggcccgg
    10681 ccaggccgtc ggagagcatc tgccgatcca gccgccagga ggccagcaca tggccgtcgt
    10741 gcgcgaagac ggcggtgacg gcgaacgggt cgtcggcgtc gtagctgagg tgggccagca
    10801 ccggacagcg gccggtaccg tgcgcaagga gctgcaccac caaggtcttg tgcacgaacg
    10861 ggttcacgcg tgggcctccg gggacaatcg gcgtagagcc ctctagtacc cccgtagcgc
    10921 ccgagatgct catccgagtg gccgattgcc gtggaccgtg cgcgacgcgg ccggaccggt
    10981 cgccccggcg gctgtcaggc gaaggcctcc cgcagggccg gcagcagggt cttcgccgac
    11041 cagtcgatga actcctgctg ggagtcgccg ccgatctgca cgagggcgac ctccccgaac
    11101 ccggcctcca cgtagggccg tacggcctcc acgaacgcct ccgggtcgtc gccgcacggg
    11161 atcgcggagg cgacgtcgtc ctcggtgacg aactgggtcg cggcctcgaa ggagtcgggg
    11221 tgcggcagct cggcgttcac cttccagccc aggccgaacc agcggaactg ggagtgtgcg
    11281 cgcttgaccg ccctctcccg gtcggtgtcg aagcacaccg gcagttggcc gacccggggc
    11341 ttgccgctgc cgccgtgccg gtcgaaggcc tccagcagac ccggcttcgg ctccgtcgcg
    11401 atgaccaggt cggcgaggtg cccggcgagc ctgcacgact gttcgccgga gacggcgaga
    11461 ccgatcggcg gcgcctcctg cggcaggtcc cacagccggg ccgactccac gtcgtagtgc
    11521 tgcccgtgat gcgtcacatg gccgccctcg aacagcgcgc ggatgatctg cacggcctcc
    11581 tcgagcatct cgtggcgtac gtccaccggc ggccagccgc cgcccaccac gtgctcgttc
    11641 aggttctcgc cggcgcccag gcccagccgg aacctgccct cggacaggag ctgcaccgtc
    11701 gccgccttct gcgccacgat cgccgggtgg tagcgcagga tgggacaggt gacgtaggtc
    11761 atcagcggga tccgcgaggt ggcctgggcg gcggcgccga gcacactcca cgcgtacgag
    11821 gcgtgtccct gcgagcgcag ccacgggaag tagtggtccg aggtcaccga gaagtcgaac
    11881 ccggcctcct cggcctgcac caggtggttc accaggtccc gggggccggc ctgctcggtc
    11941 atcatcgtgt atccgatttg caccatggga agcgagtccc cggctcggcc gccggaaaac
    12001 ggccggcggc cgccctgtca gtccttcggc gcacggaagg tcccgaggaa cgtccgcagc
    12061 gccagccggc cggccgcgtt cccccagacc ccggccgggg tggtgaagcg cagggagaac
    12121 ccccgggccc cgcccagcag gaagccccgc ccgaaggtgt gggtccgcga gcgccccgat
    12181 cccgtcagcc actccaggtc ggcggccctg cggccctggt aggtggtggc ccggacggct
    12241 ccgacgcggt gatagccggc cagccgcgcc agcccgggct cgacgtcgtc ccgccagacg
    12301 gcgaccggat cggggccgac gcgctcgctg taggtgacgg cgagggtggt cgagtccccg
    12361 ccgcggccga aggtgacccg gtaggcgagg ccggccaccc gggaggtggt cagccgccgc
    12421 cagccgtcgg gcagcgccac cgagaagccc tccggggcgg tgtaccggtg gtagccgggc
    12481 ggcagggcgg gggaggccga cgcggtcggg acgggcgtgc cggcgcggcc ggtgtgccgg
    12541 tcggacgggg cggccggggt ggtggcccgg cgccgcggcc cggcgctgtc cgtgcccggc
    12601 agcgcgccgg ccgcggccag caccgcggcg gcgacggcgg ccacggcgag cgcggcgccg
    12661 acggccagga gccgccggcc gtgccgggga ccggcggcgg cgaaccggga cgcgccgcgc
    12721 atccggggcg tgggcgcggg ctcgtggtcc gcgtccgtgt cctcggtcag tgccctggtc
    12781 agggcctgac ggaccaccgg ccgggtcagc cgttcccgtg cgtccttgcg cagcagcccc
    12841 tgcacggccc gggtgagcgg gccggcgcgc agcggggtgc gcaacggcag ccggtcgacg
    12901 gccttcagcg tggcgtcggg ccggccgcgg tcccggaacg gcggccggcc ctcgaccatc
    12961 gtgtacagca gggctcccag ggcccacagg tcggcggcgg ggccgacgcg ttcgtcgcgg
    13021 gcctgctcgg gcgaggcgta cgagggtgcc gtgagccgcg gcaccagggt cgcgccggcg
    13081 agcccgaacc cggtgacgac gaccgggccg ccgtcccgca cgaagacctg gccggggctc
    13141 agttccccgt gcgtgatgcc ctcgtcgtgc gccgaccgca gtacgtcgag caggtccagg
    13201 ccggtgcgtg cggcgcgcac cgggtggaag gggccctccc gggcgaggag ttcgccgagc
    13261 ggtgtgccgt cgatccactc ggtgaccgtc cacagggtgc cggcctccac cacggcgtcg
    13321 acgaccgcgg cgacctggcc ggggcagagc agccgcatgg tctccccggt gcgcacgacc
    13381 cgggccgtga cgcggcgcgc ggtgtcctcg gtgacgggtt ccggcagggc cgtctgcgtc
    13441 accaggcggg gctgcccggc cgccgtgtcc tcggcgtacc accacagacg gttcgtctcc
    13501 cgggcgaaga cctccagaag ccggtaccgc ccggcgatcc actcgtgtgc ggagacgtgc
    13561 gcctcgacca tggtcatccc tcgctgaagc ccctgccgcg tctttcccag aggtacgcgg
    13621 ggcgcgcggg ggtgcgttca gcgaatcctc gattcgcgcc cccgtcccgc ctttcattca
    13681 tgcgttcgaa ggcccgtacg gtgtcgcaac ggccgtcacg tctcacggca gccgtgtcac
    13741 agcaggccga accgctccgc ccagccgtgg atctcccggg gggtcgtgtt gcccccgcag
    13801 accacgagcc cgatccgggc gccggcaccg gcccgcgccg ccacctgccg ggccgccggc
    13861 agcagacatc ccgcggccgg ctccgcccac accttggcgt ggtcggcgag gtccaggcag
    13921 ccccgcacgg cgtcccggtc cgggaccacc aggacgtcct cgacgagcgc ggacacatgg
    13981 tcgtacgtca actgcgccac cgagggcgcg ctcagcgtgg tgaccaggga ggacagcggc
    14041 accggcaccg gtccgccggc cttcagcgcg ccggacatcg cctccgcgcc ctcggtctcc
    14101 acgccccaca cccgcactcc cggccgccgg tcgcgcaggg ccgccgcgac cccggcgatc
    14161 agaccaccgc cgccgacgct gacgacgacg tccgtcagct ccccggcgtc ctcggccagt
    14221 tccagtccca cggtgccctg cccggcgatc accaccgggt cgtcgaacgg atggaccagg
    14281 gtgaggccct cgtcccgcaa ccgcgtcacc agttggaagg cactgtccat gccgtcggtg
    14341 agccggaccg acgccccggc gtcctcggcg agcgcgaggg aacgcgcggg cgcggtccgc
    14401 ggcatcacca cggtcgcctt cacgtcgagg gccgccgcca tcaccgcgag cgcgacaccg
    14461 tggttgccgc cgctgacggc gaccaccccc gccgcgcgct ccgccgcgct caacgacagc
    14521 agcttggccg tcgccccgcg ggccttgaac gagccggtcc gctggagcag ttcgagcttg
    14581 gcggtgaccg ggacgccgag cagcgcgccg agaccgggac tcgccaccgt cggcgtcctg
    14641 acgatgtgtc cggcgatccg ctgcgcggcg gcttcgatgt ccgagatgcc gatcacggtg
    14701 ctccaccctt ccggcgcgga tcgggaaccg cgccggaacg gaccttggcc cgtcgggacg
    14761 tcccaggtca acgccgtatc ggatggtggt taccgtgcgc ggtccgccaa caggtccagc
    14821 agccgtgcca ggtcccgggc ggccccgccg gccaggggcg cgtcggcgag cagcgtccgc
    14881 gcggcggccg tgtggccgcg ggcctcggcc agggccgccg cccggccgcc cgccgcctct
    14941 accagcgcgg cggcctcttt ggcccgtccg ggggagtcca gcagcgcggg caggtgccgg
    15001 gccgccgggg aaccgagcgc ggccagcacc ggatacgtct tcttccgctc ccgcaggtcg
    15061 ccgcccaccg gcttcccggt gacggccgga tcgccccaga tgcccagcac gtcgtcgacc
    15121 aactggaagg cgaccccgag gtgccgcccg gcccggtcca gggcgccgac cgcggccctg
    15181 ggcgccccgg cgagcgcggc gcccagggcg gcggcacagc ccagcagcgc gccggtcttg
    15241 ccctccgcca tcgcccggta ctccggggcc gtcacccgtt ccggcccggt ccacggccgg
    15301 gtggcgaaca gcaggtcgtc ggcctgcccg cgcaccagat cggcgagggc cgacgagagc
    15361 agccgtaccg cgccggggcc ctcgggggcc gcggcgagga catccaccgc cagcgcgaac
    15421 agggcgtcgc cggccagtac ggccggaccc gtgccgtacg cccgccacac ggtggggcgg
    15481 ccacgccgga cggcgtcccc gtccatgatg tcgtcgtgca gcagcgagaa gacgtgcacc
    15541 agctccaccg cgaccgcggc gggcaccccg gcccggccgt cggcgcccgc ggcctcggag
    15601 cccagcacgg ccagcgcctg ccgtacgccc ttgccgcccg gggcggcggc gggcgccccg
    15661 ccgacctcgc accagccgaa ggagtaggcg gccatctcgg ccatccacgg gtgcagccgc
    15721 cccaccgcgt cctccagcgc gggccgtacc agcttccggc agcgggtgag ggtgagcagg
    15781 gccgggtcct gcaccggcga gccgagcgcc gtcaccgggc ggcttccgcg tcgaggccga
    15841 actcccgctg ggcccgggcc accgtctccc gggcgtgccg cagcccgctg cgctccaggg
    15901 tccgggccag ctcggcgagt tcggcggccg tctcggcgcg gtcgcggccg aggtgggcga
    15961 gggacttggc caggccgagc cgggacagcg cctcgccgcg cggctcgctc atcgtgcgga
    16021 actccgcgag tgccagctcg tagcggtccc gggcctcggc gtggcgcccg gcgcggtaga
    16081 ggacgttgcc ctgcatcttg tggttgtagg cgagcgcgct ggacaggttc atctcgcggc
    16141 aggtggcctc cgcctcggcc agcagctcca gggcccgtgc ggtggcgccg tcacgcacgg
    16201 agaggacgtc cgcgagtccg cgcagcgccc aggcgtaccc gcgccggtcg tcggcccggc
    16261 cggctatctg tgccgcctcc tcgaacagcg cgtacgcgcg gtcgaggtcg ccggtgttgc
    16321 ggtgcatctg ggcgatgccc tccagcgccc acacggtgtg ccgggcctct ccccggctgc
    16381 gcgcctcggc cagcagttgc tcgtgcagcc ggccgaccgc cgcgtagtcg ccctggatgc
    16441 ggccggtctc cgcgaggccg gccagcgagt agccgcggac gacgacgtcc ccgccgcgct
    16501 cgccgaggtc ggcggcgagc ttcagcagtc gccgggccag cgggaacgcc ccgcgctggc
    16561 gggccagagt gccgccgctc cacagcgccc aggccatcgc ggcggtgtcg ccggcctccc
    16621 gggcggcgcg gtaactcgcc ttccaggccc ggtcggcgtc ccgcacatgg ccgagccggc
    16681 ggtgcgcctc ggcgacggcg agcccgcagc gcgccgcctc gccgggcagt ccggcccgct
    16741 cggcctcgcg cagccgctcg gtgccctcgg ccagcacgtc gaccagcgag gagttcacgg
    16801 acagggtggt cagggcgccc tggtactccg gggcgaaagc cttgccgtac atgcgtaccc
    16861 ttctatacac agggtgtata cacggtgtgc atagcgtctc ggaaaagtgc cccggcccga
    16921 gggggccggg gctcggtctg ttgccggtca agacgccggt acggcgtcgg gggttgccct
    16981 ggcggcgcgg ctcacttgtg aaggttcagt gctgctgtgc cttctggggc gtcagctcgc
    17041 tcggccgtac caccacgtac ccctcgccct ggagcataag ctgcacggcc tcacccgaac
    17101 cgccgcgcag catcgagccg agcgactgcg agcggtgcag cgaggtctcc aggtgcgcgg
    17161 tccagcccac caccgcgtcc gtgtcgacgt acaccggcgc ctgcgcggtc acgggtatca
    17221 ccagcgggtt gccgtcgcag accaggccga gccggccctg tccgctgaac acgctgttga
    17281 acaggccgcc gccggcgatg cccgacccct tcaccgtctt gatctcgtac gacaacgagg
    17341 cgtcgaaaca cagcacgttg cggccgttga ccgtgaaccg gtcaccggcc tccacctcga
    17401 cgatgaaaca gttctgcgcc tcgtgcgcga accaggcctc gccctgcccg cgcaccgcca
    17461 tgaggggcag tccctcaccg gtgaccgcac gcttgagcat gccgccgacg ccctgcccct
    17521 tgcgctcgaa cttcaggccg ccgcggtagg cgaccatggc gccctgccgg gcgtacatct
    17581 cgccgttcac cgcgtacctg aggcacttgg cgttctcgac ggacatcccc ggctcgacgg
    17641 ccggctgcac cacatgctga ctggagaaaa gatcaccctt catggggggc atcgtgtccc
    17701 ggacggcagc gttccgccaa gatcacggaa cgtgccggtt cggccacgga agagccccct
    17761 acggctcgac cgtcctcgcc ttgccgcaga acgccgagtc cagggcgccc gccagcgtgt
    17821 cgagcacctt cccgttgttc gacgtgtcgg ccatcgccgt gaggctgcgc ccgccgtcct
    17881 tcgtggcgaa cgcgtaggtg tagtacccct gcacggctcc cgtgtgcccg tacaccgaga
    17941 tcccgcagga caggtcccgc cgccgcagcc ccagcccgta cgccgtcgtg ctgttgaccg
    18001 gggtgaaccg ctccatctcg gcgagccgtg cggcggacat cagcttcccg ccgagcagcg
    18061 cgccgtagaa cgtgtcgagg tcccgcgcgc tggagatgac cgcacccgcg ctctgcgccc
    18121 aggacacggt ctgggcggtc gcgtcgaccg gcgcggcgcc cgccgtgtcc ggggtgaggt
    18181 acccgcgggc gtaccgcccc gggatcgccg tgctcgggtg gacgtagaac gtgtcgccca
    18241 gtcccagcgg cccgatgacg cggttccggt aggccgtcgc cacgggctgt cccgtgagct
    18301 tctcgatgag caggccggcg acgacgaagt tggtgttgga gtacgcgtag gcggcgcccg
    18361 gcgcgttggt gcggggcttc ttcagggaga gggcgaccag ttggcggtag gtgaagacct
    18421 tgttccgcac cgcctcgaag ccggagacgc tgtgggcgaa catgtcgttc gtgtagtcgt
    18481 acagtccgct gcggtggccg agtacctgac ggaccgtgat ccggtcgtcg ggcagcagct
    18541 tcggcaggta ccggttgacc ggcgcgtcga gcgagagccg gtgctcgtcg acgagctgga
    18601 gcaggacgac ggccgagaag gtcttggtga tgctgccgac ccggaagcgg tcctccgtgc
    18661 tgatggcccg tgcgctgctc cggtcggcga ccccgtgcgt gacccggtac gtccgcccgt
    18721 ggtcgtcgat ccgggccagc gcgcccggtg cgccctgggc caccaccgac cgcagcaccg
    18781 aggccagtcc cgccgtgtcc ggtgccggga gcgccgctgc cgccggggtg tcgtgctccc
    18841 cggccacggc ccgcgccggc accgcgagga gcgacagcgc gaccgccccg aggaccgctc
    18901 cccggaccac cgttgctgag accatccggt acccactccc atcggttcgg ttcctgatgc
    18961 gatatcggtc acattccgcc ctgggaacct aggggatcga ggcaacgtct ccacagtcga
    19021 cacacagttg gtggtccggc gatcactctg tggcgcccgt ttgcaaagga ttgccataga
    19081 agttcgcgaa atggatcatt ccggctttac gtgcacatga ctgatccgac agggttgtcc
    19141 accgggggcg tcagacgagt ccctatggcg ccaactgcgc catttctcaa ggcggttggt
    19201 gaccccggcc gccttcgaac gaaggaaccc tgatcagatt gcgtagagcg cacatacgct
    19261 ccgtggcgat cgccatcgcg gtgacgacgg ctgccacggg cctggccggt acggccttcg
    19321 cgggtccctc cacgggggtg gagcggaccg ccgcctccgc cgcctcgaac gccacggtgg
    19381 tggtggaggc ggcgcgcaca gcggccttca cgcacgcctc ggcgaccggc gtctccaagg
    19441 gcgacgcact gcacgcccag gacgtcctgc tcgacccgga gggtgcccgg cacgtccgct
    19501 tcgtccgcac gcacgacggc ctgccggtac tcggcggcga cctcatcgtc cacctcgacc
    19561 gggggctcgg ctacacgggc gtgacccgcg cggccgacca caccgtcaag ccggccgccg
    19621 aggccaggct gaccccggcc caggccgccg ccaaggccgc cgaggccgcc aagggcgacg
    19681 cgggcggtgt ccagctcgtg ctggacgccc ggggcggcgc ctccgcgctc gcctaccagg
    19741 tcaccgtcac cgccgggggc aacccccaca cggtcgtcgt ggacgcggtc accggcaagg
    19801 tgcgcagcaa cacgcccgtg cgggacgagt tcctgtcgcc gaagctggtc gacaccctgc
    19861 gcgagcgtgg cgagagcgcc gacccggtga ccggcagcgg ctccgcctcc ggcgcgtccg
    19921 gcctgctcgg ctcgggcgcc tccggcgtca cgcactaccc gtcggccgcc aagggccccg
    19981 gcaagacgct cttcgtgggc acggtcggtc tcaccaccac gcagacctcg cgcggccact
    20041 tccagctcaa ggacccgaac cggtacggca ccgagacccg ggacgccaag ggctcggaga
    20101 cggagaagtt cagcgccggc acgaagttca ccaacacgac cgacgtgtgg ggcaacggca
    20161 agaccaccag ccgggtcagc gccgccgccg acgcccagta cggcatcacc aagacgctgg
    20221 acttctacaa gggcacgttc gggcgcaagg gcatcgccaa caacagcaag gccgcccagg
    20281 cgatggtcca ctggggcaag aaggtcggca acgccttctg ggacccgacc tgcaactgca
    20341 tgctgtacgg cgacggcgac ggcgacatgt tcaagaagcc gctcgtcgtc ctcgacgtca
    20401 ccggccacga gctgacccac ggcgtggtgg aggcgaccgc caacctccag ccgacgatcg
    20461 tcgacaagta cggcaaccag tacggcgagc ccggctcgct caacgagtcc ctcgcggaca
    20521 tcttcggctc gaacgtcgag ttctacgcca agaacacgaa ggacacgccg gattacctga
    20581 tcggcgagaa gctgggcctc gcgcagaagt tcctgcgccg cctggaccac ccgtcgctcg
    20641 acaagctcga aggcaccatc gactactgga agccggaggt gtacggcacc gaggtgcacg
    20701 ccggttcggg tgtctcctcg cacgcctact acctcctcgc cgagggcagc ggcaagaaga
    20761 cgatcggcgg cgtcgcctac aactcgccga cgtaccacaa cctcacggtc aaggggatcg
    20821 gccgcaccaa ggcgaccgcc gtctactacc gtgcgctcac ccgctacatg gtctccgaca
    20881 ccgacttcca ccaggcgcgc ctcgcgacgc tgaaggcggc caaggacctg tacggcgcga
    20941 acagcaccga gtacaagacg gtggacaggt cgtggtcggc ggtcaacgtc accgccgcca
    21001 acacgccggc cgcccgccac tgacggacgg cagcacaccc cgcagtaccg gatgccccgc
    21061 cccgcgcggg gcatccgtgt tccccgcccc gcgcggacgg cccggcgccg tcagggggcg
    21121 gcggctcagc gcagggtctg cgcccagtcc gccgggaccc ggcccgccgg accgggcgcc
    21181 ggctggtcgg cggggtggcc ggccggggga gcgagttcgg gcccggagcc gtacagctcc
    21241 tccgtggcga agttccagaa ccaggcctcg cccggctcga agctgcggat caccgggtga
    21301 cccgtctccc ggtagtgggc ggtggcgtgc cggccggggg agtcgtcgca gcagccgatg
    21361 tggccacacc gcgcgcaccg gcgcaggtgg aaccaccagc cgccggcctc ctcgcactcc
    21421 acgcagcccg tgccgctcgg cgggacccgg gggtcgattc cttcgacgtc gttcattcct
    21481 gctcctcgtc gtgcgtctcg gcggtcaggg gcagcagcac ctggaagcgg gtgtcgccgg
    21541 gctccgactc cacccgcagg gtgccgtggt gcttgttgac gacgatccgc caggagatgt
    21601 ccaggccgag cccggtgccc tcgccgaccg gcttggtggt gaagaacggg tcgaagatcc
    21661 ggtccctgat ctccgttggc acgccgggcc cggtgtcccg gaactccacc agcagccgct
    21721 cgtggtcgag cgcggtccgt acggtcagcg tgccctcccc gccggcgctc cggacggccg
    21781 agacggcgtt gtcgatcagg ttcgtccaca cctggttcag ctccgccgga taggccggca
    21841 ccggcgggag cgtacggtcg tactccttga cgaccccgat gcccgggccg atcttcccgg
    21901 acagcatcag cagcgtgctg tcgaggagtt cgtggacatc cacctcgcgg tacggcgccc
    21961 ggtccaactg cgcgtactgc ttggccgcgt cgaccaggtg cgagacgcgg gtggtggagt
    22021 cctcgatctc gctcatcaac agctcggtct cgatggtgta gttcagccat ccgaccgcgt
    22081 tgggcaggat ctcctcgtcg acggccgccg cgacctgctc cagccagtcg acgtcgagtc
    22141 cggcctgcac gaacgtgggc gccacctgcc agccctgctc gaagccgtgg tccgccagcc
    22201 agtcggtgag ccggtcctcc cggtcggacg cctccagcgg gccgagcacc ggcgccttcg
    22261 ccacccgttc ggcggtgcgc tcctggatct cgatcaggct cgccagcacg tcacgggaga
    22321 acggcccccc ggcgatcacg ccgagcttgt gccgcatctt cgcgacccgt tcccgcaggg
    22381 ccgaggtggc ccgcacggcc gccgccgccg ggttgttcag ctcgtgcgtg agcccggccg
    22441 acaacgagcc gagggcgagc agccgttccc gctgcccgat catggcctgc gtgttcttcg
    22501 agccgaagaa cagcccctcc agcaggtgca cggccatcgg gaaccactcg cgcatcacct
    22561 ccgcgaagag gtccgccggc agcacgaaga accgggtcgg ctccgtcacc cgcatcgagt
    22621 tgttgtagac ctgcggcacc cggtcgccga ggtaggcctg catcgcgccc gcgtacaccc
    22681 cgggctggga ggtccgggtg acctccacgt cgtcgccgcc gacccggcgg gacagcacga
    22741 ccgtgccctc caccatcacg aagaagcagg tggcggggtc gccctcggtg tacacgggtc
    22801 cggcctggaa cagctccacc cgtcccgcgc cgcacagccg gcccagttgc tgcccactca
    22861 gcttctcgaa gaggaacagc gagccgatct cccccgggct gcacggcatg acctgcccgc
    22921 tcatgactgc tccagatacc ggtggacgag catcacggcc atggctccct ctccgacggc
    22981 ggacgcgacc cgcttggcgg actcggcgcg ggcgtcgccc gccacgaaca cgccgggaac
    23041 actggtctcc aggtggtacg gcggccggtc cagctcccag ccggccggcg ggcgtccgtc
    23101 ggcggtcagg tcggggccgg acaggatgaa gccgcgcccg tcgcgcagca ccgcctcgcc
    23161 cagccagtcg gtcagcgggg cggcgccgat gaagacgaac atccactgcg cgtcgacctg
    23221 ttcggtctcc ccggtcacca tgtgacgcag cgtcagccgc tccagccggc cggagccgtg
    23281 cgcctcctcg acgaccgtgt ggcagcgcac cgagatgttc ggggcctcgc cgatctgctg
    23341 gatcaggtag tacgacatgg acgccgacag gtccgggccg cgcaccagca gcgtcaccga
    23401 cttcgcgccc cgggacaggt acatcgccgc ctggcccgcc gagttggcac cgccgacgat
    23461 gtacacgtcc tggccctggc aggaggccgc ctcggtcagc gccgagccgt agaacacccc
    23521 gcagccggtg aggtcggtgc agcccgcggc gtccagctgc cggtactgca ccccggtcgc
    23581 caggatcacg ctgtgcgcgg cgatcgccga gccgtccgcg aaccggacga cccgcgcggc
    23641 gccgcaggcc tccagcccgg tcacctcgcg cgcggtcagg atctcggcgc cgaacctggc
    23701 cgcctgccgc cgcgcccggt cggtgagctg ggcgccggag acgccgtcgg ggaagccgag
    23761 gtagttctcg atgcgggagc tctgccccgc ctgcccgccg gtcgccgacc gctccaccag
    23821 cacggtccgc aggccctccg acgccccgta cacggcggcg ccgagcccgg cgggtccgcc
    23881 gccgatcacg acgaggtcgt agaactcgga cgtcggcgtc gtcgccaggc ccacccgcgc
    23941 cgccagttcg ggtgcctccg gctcgaccag ggcgctgccg tccggggtga tcaccagcgg
    24001 gagccgctgc ccgtcctgcc cggccgccgc cagcagccgc cgcccctccg gttcctccac
    24061 cgagtaccag cggtagggca cctggttgcg ggccaggaac tcgcgcacgt ccgaggagcg
    24121 cgccgaccag cggtggccca cgatcttcgt gctgggcacc ggccggtagg cgcgggtgcg
    24181 ccaggcctcc agcaggtcgt ccaggacggg gtagagcttc tcctccggcg ggtcccacgg
    24241 cttgagcagg tagtggtcca ggtcgaccac gttgatcgcg tcgatcgccg cgtcggtgtc
    24301 ggcgtacgcg gtcagcagta cgcggcgcgc gcccggatag acgtcgagcg cctgctccag
    24361 gaactcgatg ccgttcatct gcggcatccg gtagtcggcc aggatcacgg ccaccaggtc
    24421 gccgcgcagc ttcagctcgc gcagcgcctc cagcgcggac tccccggact cggcgcggac
    24481 gatccggtac gacgcgccgt agcgccgcct gagatcgcgg gcgacggccc gggagacccc
    24541 cgggtcgtcg tccacggtca ggatgacggt ccgcgctgcg tcggcggcct gtgccatacg
    24601 tctcccaccc cgggtgtcgg ttccacgggg cggtgtcgtg gggaccaccg caccggttcg
    24661 aagccatcgt atgttcgatc gcccgggtcc gctcaggtgt acggggcgta cccggtgcgg
    24721 ggcggacggc ccggccacgc gatcatcgtg cccgtgcgct cccgtgcctg atagtgggca
    24781 ccagcaccac gaggaccggc gacgaggagg cccagggatg acacgcccga tcacggcagg
    24841 ggtggacggt acggaggaga gtctggccgc gctggactgg gcggcccggg aggccgtccg
    24901 ccgggggctg ccgctgcgcg tggtccacgc gtggcgttac gccgagacgc tcgccgccgc
    24961 cgaccgggac acccagcacg gctgggtgtc ccggggcgtg tcacaggccg tgcgtgccgc
    25021 cgccgggcgg cacccggacc tgaccgtgag cgtcgacgtg gtggaggacg gggccgctca
    25081 ggcgctggcc ggcgcggcgg ccgacgccga gatgctggtg ctgggctcgc gcgggcacgg
    25141 acccgtggtc ggcttcctgc tcggctcggt cggccagcag gtcatcgcgg aggcggcccg
    25201 gcccgtggtg ctggtgcgcg cggaggccga gaccacggcc gaggccgccg ggcgggacgt
    25261 cgtggtcggc caggacggcg cgcccgagga cagcgcggcg gcgctgcggt tcgccttcga
    25321 gacggcggcg gcccgcggtg cgaccgtccg ggccgtccgg gcgtggaccc tgccgccggt
    25381 gttcgcctac agccccggct cgctgaggct gctcgacgac gcgggcggcc tcgaaccgta
    25441 cgagaggcag tctctggccg aggccctcca gccgtggcgg gagcggttcc ccgaggtgcc
    25501 cgtggcggag cacgtcgaga tgggcagcgc gggccatgtc ctgctgtcgc tgaccgggcg
    25561 ggcccaactg gtggtcgtcg ggcgccgggc gcaccgtacg gccgtcggcg cccggatcgg
    25621 ctcggtcgcg cacggcgtgc tgcaccacgc ggactgcccg gtggccgtgg tcccgcacgc
    25681 ctgagccacc gggctactcg gggtccgtcg gctccagcgt ggcccgggcc ctgggcagca
    25741 cgcggtcgat gtagtcctcg actgcggtgt cgaggcctat gtcgtgctgg gcgcgctcgg
    25801 acaggtacca gcggt
//
