LOCUS       NZ_CP033073            21086 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces dangxiongensis strain Z022 chromosome, complete genome.
ACCESSION   NZ_CP033073
VERSION     NZ_CP033073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces dangxiongensis
  ORGANISM  Streptomyces dangxiongensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     The genome of Streptomyces dangxiongensis Z022
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) State Key Laboratory of Cryospheric
            Sciences, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. version 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 213.0x
            Sequencing Technology             :: Illumina and Pacpio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003675325.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 04:16:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,241
            CDSs (total)                      :: 7,151
            Genes (coding)                    :: 6,614
            CDSs (with protein)               :: 6,614
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 537
            CDSs (without protein)            :: 537
            Pseudo Genes (ambiguous residues) :: 0 of 537
            Pseudo Genes (frameshifted)       :: 320 of 537
            Pseudo Genes (incomplete)         :: 281 of 537
            Pseudo Genes (internal stop)      :: 26 of 537
            Pseudo Genes (multiple problems)  :: 83 of 537
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:47:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2720823
            Orig. end                         :: 2741909
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033073.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Binglin Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11086)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(478..492)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     misc_feature    complement(618..633)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.49"
                     /tool="antismash"
     gene            769..1533
                     /locus_tag="D9753_RS11910"
                     /old_locus_tag="D9753_11910"
     CDS             769..1533
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973740.1"
                     /locus_tag="D9753_RS11910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11910"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_121786997.1"
                     /transl_table=11
                     /translation="MSTDVSSAENETGTTVRTARVPKYYRLKKHLLDMTETQAPGTPVP
                     PERTLAAEFDTSRTTVRQALQELVVEGRLERIQGKGTFVAKPKVSQALQLTSYTEDMRA
                     QGLEPTSQLLDIGYVTADDRLAGLLDITAGGRVLRIERLRMANAEPMAIETTHLSAKRF
                     PALRRSLAKYTSLYTALAEVYDVHLAEAEETIETSLATPREAGLLGTDVGLPMLMLSRH
                     SLDRGGDPVEWVRSVYRGDRYKFVARLKRPVD"
     misc_feature    1573..1587
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.35"
                     /tool="antismash"
     gene            1658..1933
                     /locus_tag="D9753_RS11915"
                     /old_locus_tag="D9753_11915"
     CDS             1658..1933
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005480428.1"
                     /locus_tag="D9753_RS11915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11915"
                     /product="DUF3311 domain-containing protein"
                     /protein_id="WP_205614126.1"
                     /transl_table=11
                     /translation="MSETPEVRPPVVTPVRVVIALCLVAPFVAMLWVGSYAETDPTFVG
                     IPFFYWYQMLWVLISTALTVLAYQLWQRDQRARSRSAAGRDEEAAK"
     gene            1930..3540
                     /gene="mctP"
                     /locus_tag="D9753_RS11920"
                     /old_locus_tag="D9753_11920"
     CDS             1930..3540
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006848 - pyruvate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mctP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444565.1"
                     /locus_tag="D9753_RS11920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11920"
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_121786999.1"
                     /transl_table=11
                     /translation="MKDGVNGVALGVFIFFFLAVTVMGFLAARWRRTDNEQSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGASGFFAVPYTILVYPLIFTFLPRLW
                     SVSHRHGYVTTSDFVRGRFGSKGLSLAVAVTGILATMPYIALQLVGIQAVLDVMGVGGG
                     ENTNWFVKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPVKLGG
                     FDDIFAKAGEKFSTTGVGGVVPAPAGQWTYATLALGSALALFMYPHSITATLSSRSREV
                     IRRNTTILPLYSLMLGLLALLGFMAIAAGVKVTNGQLAIPQLFEDMFPDWFAGVAFAAI
                     GIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPEQETRVSKIVSLLVKVGALVFVLTM
                     DKTVAINFQLLGGIWILQTFPAMVGGLFTRWFHRWALLAGWAVGMVYGTVAAYGIASPT
                     QKHFGGSAKEIPGIGEIGYIGLTAFVLNVLVTVVLTFVLKAVKAPEGIDETRPEDYTSD
                     AGDPGVQVELPPATAGASH"
     misc_feature    3741..3755
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     misc_feature    3772..3786
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.05"
                     /tool="antismash"
     misc_feature    3780..3793
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     regulatory      3808..3886
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    3860..3875
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.01"
                     /tool="antismash"
     gene            4031..6388
                     /locus_tag="D9753_RS11925"
                     /old_locus_tag="D9753_11925"
     CDS             4031..6388
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674902.1"
                     /locus_tag="D9753_RS11925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11925"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_121787000.1"
                     /transl_table=11
                     /translation="MTIAPADPASVTELKTDGPGTALLRTLTELTADLPDADPGRVAAA
                     ALRGRSARADEAELRELATEAAAGLISEDPAYSKLAARLLTLAIRDEAASQGVTSFTGS
                     VAVGHREGLVADRTAAFVRLHAERLDALVDGAADDRFGYFGLRTLYSRYLLRHPITRKV
                     VETPQHFMLRVASGLAEDDTSRAVDEVAALYRLMSRLDYLPSSPTLFNSGTRHPQMSSC
                     YLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGTNGHSNGIVPFLK
                     TLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLAHWVPDE
                     FMRRVNADEQWSLFSPAEVPELVDLWGEEFDAAYRRAEAAGLARKTIPARDLYGRMMRT
                     LAQTGNGWMTFKDAANRTANQTAEPGSVIHSSNLCTEILEVTDDGETAVCNLGSVNLGA
                     FVRDGDIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGAMGLQDVFF
                     KLRLPFDSPEAGALSTRIAERIMLAAYEASADLAERNGPLPAWERTRAARGVLHPDHYD
                     VDLTWPERWDALRERIASTGMRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRETLS
                     GEFLQVNSYLVRELKDLGVWDARTREALRDANGSVQGFAWIPEEVRRLYRTAWEIPQRG
                     LIDMAAARTPFLDQAQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIARA
                     AQAQPAIPVQQAADPDAVACSLENPESCEACQ"
     gene            6388..7401
                     /locus_tag="D9753_RS11930"
                     /old_locus_tag="D9753_11930"
     CDS             6388..7401
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674901.1"
                     /locus_tag="D9753_RS11930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11930"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_121787001.1"
                     /transl_table=11
                     /translation="MTTRTTRLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLH
                     SDVTDLARLTPEEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEE
                     AVHVQFYLTLLDTYLPDPDDRAAAFAAVENIPSIREKAGFCFKWINEVEKIDRLETQAD
                     RRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSFAFE
                     VVDTVRKEEPELFDDALRQEVTDMLGEAVEAELQFARDLCGDGLPGMNTESMRQYLECV
                     ADQRLTRLGFAPVYGSQNPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF"
     gene            complement(7314..7556)
                     /locus_tag="D9753_RS36500"
     CDS             complement(7314..7556)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047586.1"
                     /locus_tag="D9753_RS36500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_163010545.1"
                     /transl_table=11
                     /translation="MNGNQIEGLIGMGTTLGILVLLVLPSVLGVVRERRIDRQLRQAQE
                     ARGDSRDQKSSSRSTVPSTATWYADGRRSKKFVSS"
     gene            7650..8612
                     /locus_tag="D9753_RS11935"
                     /old_locus_tag="D9753_11935"
     CDS             7650..8612
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018544423.1"
                     /locus_tag="D9753_RS11935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11935"
                     /product="GlxA family transcriptional regulator"
                     /protein_id="WP_121791026.1"
                     /transl_table=11
                     /translation="MLKNVAVVLLDGVQPFELGVVCEVFGIDRSDDGLPVYDFAVVSAE
                     GPSLGTHCGFTVSTPYGLERLEEADLIAVPAGQAYAERAFPEELLTALRRAVDRGTRVL
                     SVCSGVFVLAAAGLLDGRRCAVHWHHAEQLARRYPRLEAEPDMLYVDEDPVITSAGTAA
                     GIDACLHIVRKEQGPEVANKIARRMVVPPHRDGGQAQFIERPLPKAPCDTVGEVLAWME
                     AHLDQEVTVEQLAARAHLAPRTFARRFQQETGTTPYRWILRQRVLLAQELLEGTDETMD
                     AIAGRTGFGTAAALRHQFVRALGTTPQAYRRAFRGPQAA"
     gene            complement(8634..10004)
                     /locus_tag="D9753_RS11940"
                     /old_locus_tag="D9753_11940"
     CDS             complement(8634..10004)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674897.1"
                     /locus_tag="D9753_RS11940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11940"
                     /product="cytochrome P450"
                     /protein_id="WP_121787002.1"
                     /sec_met_domain="p450 (E-value: 1.2e-66, bitscore: 224.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVKPATPRTTALREPPLAPGAVPVLGHGLKLVRDPLAFMSG
                     LRDHGDIVRLRLGPKTVYAVTAPALTGALALSPGFSIAGPLWESLEGLLGKEGVATANG
                     SRHRRQRRTIQPAFRLDAIPQYGPVMEEEAHRLTERWKPGETIDCTSESFRVAVRIAAR
                     CLLRGDYMDERAERLSTDLATVFRGMYRRMVIPLGPLYRLPFPANREFNRALADLHLLV
                     DEIVAERRASGQKPDDLLTALLEAKDDNGEPIGEQEIHDQVVAILTPGSETVASTVMWL
                     LQALAAHPEHAERVRAEVESVTGGRPVGFEHVRALKHTSNVVVEAMRLRPAVWILTRRA
                     TTDAVLGGYRIPAGADIVHSPYAIQRDARSYARHLDFDPDRWLPERAGEVPKYAMSPFS
                     VGNRKCPSDHFSMTQLSLITAAVSAKYRFERAAGSDESTRVGITLRPQNLLLRAMPW"
     gene            complement(10001..11086)
                     /gene="cyc1"
                     /locus_tag="D9753_RS11945"
                     /old_locus_tag="D9753_11945"
     CDS             complement(10001..11086)
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190552.1"
                     /locus_tag="D9753_RS11945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11945"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_121791027.1"
                     /sec_met_domain="T1TS (E-value: 8e-64, bitscore: 215.3,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAFPRSTTVTRTAVVVPPSLALPVIESAFPRRLHPYWPRLQENT
                     RLWLLEKRLMPADKVHEYADGLCYTDLMAGYYTSAADEVLQAIADYSAWFFVWDDRHDR
                     DIVHGRAGDWRRLRHRLHAALDAPGHHVHHPDPLVAGFADTVLRLYGLLSRTWNLRFAR
                     HFHAVIEAYDREFRNRTEGYVPGVEEYLALRRLTFAHRIWTDLLEPSAGCELPDAVRKN
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHEGLTLEEAVDDVRRRVE
                     ECAGEFLDAEQDALRLAHDIDDGTARGAELGAAVRTCVDAMRNWFSSVYWFHHESGRYM
                     VDNWDDRSTPPYVTNEAAGEK"
     gene            complement(11375..12025)
                     /gene="def"
                     /locus_tag="D9753_RS11950"
                     /old_locus_tag="D9753_11950"
     CDS             complement(11375..12025)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="D9753_RS11950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11950"
                     /product="peptide deformylase"
                     /protein_id="WP_121787003.1"
                     /transl_table=11
                     /translation="MAHQDTDQQHAGVLPVDDEGYVVDTEDCEEREQAWRERGTSRPIT
                     VVGNPVLHKECRDVTEFGEELQQLAADMFASQRTAEGVGLAANQIGVDLKVFVYDCQDD
                     EGARHVGVICNPKLVDLPAEQRRLDDSNEGCLSVPTAYASLARPDYAEVTGQDEQGNPV
                     KVRGTGYFARCLQHETDHLYGHLYIDRLSKRDRKDALRQMAENEPRYPVVAND"
     misc_feature    complement(12044..12053)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     gene            complement(12091..13073)
                     /locus_tag="D9753_RS11955"
                     /old_locus_tag="D9753_11955"
                     /pseudo=""
     CDS             complement(12091..13073)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="D9753_RS11955"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11955"
                     /product="tetratricopeptide repeat protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRIFGKARHRPSASWRQATDRAFTLIGDGRYEDAGELLTRAADLE
                     PWLAESWFNLALLHKFRHDWEQARAAGLRAVALLDREAGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLKVPGGAAVSGEPLGMELGSAAVRLSPEGEAEVVWGRRLDPARMEVLSIPL
                     PSSGRRWGEVVLHDGVSRTASARRPPGTPTRSSTRSSCGHRHPSPPGWSCWRRPRRRTG
                     TRWSGSPPTPGSPRRTGRRRCGCCAGRARSRGCRPTRARGCTWTRTTTASRGIPGRWGT
                     GRTGSCGCPSGSAGSRRRPRSCAGCWTDGSRTARTRGTGGIWKRSA"
     gene            complement(13173..14465)
                     /locus_tag="D9753_RS11960"
                     /old_locus_tag="D9753_11960"
     CDS             complement(13173..14465)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674893.1"
                     /locus_tag="D9753_RS11960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11960"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_121787004.1"
                     /transl_table=11
                     /translation="MSPLRLIHGAAVLVAAGSLAVTLWTGLEDRGVALAFGTLIAVGEL
                     TRWSDAQERQAAPLGAAGSLSYALLGADAGRPAQHGAAQVVTVVLVAALLGAVPHIWSG
                     GTPTADHLARRVLTVGFAALCFQPPYDNRVFASWTGPAYPLLLLTLLALTSLCGAVLAA
                     TLAHCRSGRPFGPLLREELRGLLGIGSAVCATGAVMALAVAVAGLWALPVFCLPLLLVQ
                     VSLRRYAAVRATYRQTIASLARATEIAGCTPAGHAHRVAALSLAVGRDLGLTGPELTVL
                     EYAALMHDIGQLSLVDPVPAGATAVLPAAEQRRIALLGGAVVRQTGVDAAVAVVVERQA
                     DPCPEQPLAARIVRTVNAYEEKARDAGPEGPLHALEELRLGTADDYAPEVVESLARVLA
                     RPRGWRATVPADAGARRTGLSDPAPGWVTHG"
     gene            complement(14462..15766)
                     /locus_tag="D9753_RS11965"
                     /old_locus_tag="D9753_11965"
     CDS             complement(14462..15766)
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674892.1"
                     /locus_tag="D9753_RS11965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11965"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_121787005.1"
                     /transl_table=11
                     /translation="MDAVPARARGCVAAAALLAALCLLRLPTSHVPWWEPCLLAALYAA
                     CEHVVRRRLDGTFYPVLLAGAFLLPPPAAALVPLPALLLPPAGHRAALSRRVWRAVRPA
                     LAVCGAAHVHRALGGRDAVVGSDFPYALLPAGAAVLVLCLVLTLLDGGLRAAAGLVPPR
                     RAWRGLLARSLAPVAVHGLAGLMMAVLWRSPYGPSAALLVLLPMCVSCWVFAQYHRERA
                     AHQATIRALVQAVDIKDGYTRGHSERVGQASVLIARELGMDDDRVETLRFAGILHDVGK
                     LGVPTRLLRKDGPLTPEERRIIELHPEYGHEMVRGISFLGEARAAILHHHERLDGSGYP
                     YGLAGDQIPECARIVAVADAFDAMTSTRSYSRARPVEAAVTELERCAGAHFDPRMVGAL
                     VRAVRRCGWRPTVTADEPAYVMTPAERAPRTGAAR"
     gene            complement(15879..16190)
                     /gene="rsrA"
                     /locus_tag="D9753_RS11970"
                     /old_locus_tag="D9753_11970"
     CDS             complement(15879..16190)
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="D9753_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11970"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_121787006.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEVLDHLYEFLDSEMPDVDRDKFQHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGHDDVPADLRAKVMGRIDLIRSGQTVPGHDVTRTPTAPQES"
     gene            complement(16187..16882)
                     /locus_tag="D9753_RS11975"
                     /old_locus_tag="D9753_11975"
     CDS             complement(16187..16882)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="D9753_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11975"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_205614127.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDNGQAGPPEDQGVSAEASGETTVERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKSALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SNEAKGSGS"
     gene            complement(17139..17768)
                     /locus_tag="D9753_RS11980"
                     /old_locus_tag="D9753_11980"
     CDS             complement(17139..17768)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058310.1"
                     /locus_tag="D9753_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11980"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_121787008.1"
                     /transl_table=11
                     /translation="MNTETVDTDAGPARITWHPAREARLVLAVSHGAGGGIEARDLHVL
                     AGTLPARGVTVALVEQPWRVAGKKVAPAPKTLDTGWRGVWPALARPGLPVISGGRSAGA
                     RVACRTAAELGAHAVLALSFPLHPPGRPERSRAGELLGTGVPTLVVQGGNDPFGRPEEF
                     PAGDFDLVEVPHADHGLAVPRRADLTQEQALDLVGARVAEWTLSLG"
     gene            complement(17770..18585)
                     /locus_tag="D9753_RS11985"
                     /old_locus_tag="D9753_11985"
     CDS             complement(17770..18585)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="D9753_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11985"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_121787009.1"
                     /transl_table=11
                     /translation="MCGRYASSRGPEDLAGVFEVEHWDPEETLEPDYNVAPTKEVHAVL
                     DRPLKDADSPRPVRQLRRLKWGLVPSWAKTPEGGARMINARAETVHEKPAYRRAFAARR
                     CLLPADGYYEWVTGSQERELEVEGRKKRPRKQPYFVLPADGSVFAMAGLYEFWRDRTLP
                     DDHPRAWWATCSVITTEAERDPLAVAPAEGPRSLADIHPRMPLMLTPDRWDAWLDPSRT
                     DPDELRALLAPPPPGLMRAYPVSTAVSNVRNNGPELLKELQAPEEGTLF"
     misc_feature    18676..18690
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            18692..19414
                     /locus_tag="D9753_RS11990"
                     /old_locus_tag="D9753_11990"
     CDS             18692..19414
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674886.1"
                     /locus_tag="D9753_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11990"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_121787010.1"
                     /transl_table=11
                     /translation="MDSLAATALPGLWDRLTGTQPDPGLWVILATLAAALAVVVPHPVW
                     RISRNAITIAHEGGHGLVALLTGRQLTGIRLHSDTSGLTLSRGKPYGLGMILTAAAGYT
                     APSLLGLGGAALLATGRITLLLWVATALLLAMLLMIRNAYGVLTVVLAGGAFLLVSWLA
                     GPQVQAAFAYAVVWFLLAGGVRPPFELQAKRARAGAGDSDADQLSRLAHVPAGLWLFLF
                     HAVSLSSLIGGGRWLLEG"
     gene            19443..20759
                     /gene="aroA"
                     /locus_tag="D9753_RS11995"
                     /old_locus_tag="D9753_11995"
     CDS             19443..20759
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674885.1"
                     /locus_tag="D9753_RS11995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_11995"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_121787011.1"
                     /transl_table=11
                     /translation="MAPNPAPTAPWPAPHASGAVDATVHVPGSKSVTNRALVLASLASE
                     PGWLRRPLRSRDTLLMAGALRAMGVEIEEGVGPDGTGEAWRVLPTGLRGPATVDVGNAG
                     TVMRFLPPVAALADGPIRFDGDPRSYERPLHGVIDALRALGARIDDDGRGALPLTVHGG
                     GALDGGPVSVDASSSSQFVSALLLSGPRFNQGVEVRHTGATLPSLPHIRMTVDMLRAVG
                     AQVDTPESGGEPDVWRVTPGALLGRDLTVEPDLSNAQPFLAAALVTGGKVLVPDWPART
                     TQPGDRLREIFTEMGGSCELTDYGLVFTGSGAVHGIDVDLGDVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRPLRGGVFHTYEDHRM
                     ATAGAVIGLAVEGVRIENVATTAKTLPDFPALWTGMLGQ"
ORIGIN
        1 gccgcgaggt gctcgaaccg ctcggcatag acatggacgc gttcgtgggg ccggacggca
       61 cggccgagga cgtccaggcg gcgtgcgagg cgtacgaccg cgcgctcgtc gaggccggcg
      121 gggtggacct gcaactgctc ggcatcggca ccgacgggca catcgggttc aacgagccgt
      181 gctcctcgct cgcctcgcgc acccggatca agaccctgac cgagcagacc cggatcgaca
      241 acgcccgctt cttcgacggc gacatcgagc aggttccgca ccacgtcatc acccagggca
      301 tcgggaccat cctggaggcc cggcacctgg tgctgctggc caccggcgag ggcaaggcgg
      361 acgcggtcgc cgcgaccgtc gagggcccgg tcgccgcggt ctgcccggcc tccgcgctcc
      421 agctccaccc gcatgccacg gtggtcgtcg acgaggccgc cgccgccaag ctgaagctgg
      481 ccgactactt ccggcacacg tacgccaaca agcctcagtg gcaggggatc tagccgggga
      541 acaggggtgt acgggatgcg gagagacgtc ccgacgcggg ggcgggcgcg tcgtcgcccg
      601 cggcctccgg cgtccctgat ggactagacc aacggggggc gcgacggtat acagagggga
      661 tcacggagcg tgcgggggga gtcccgacac ggcaacccgt gccacgatgt gagccgtggc
      721 cgatgggatg tcggtcgctt tcggcactcg gagccgggaa ggcagagcat gagcaccgac
      781 gtcagcagtg cggagaacga aacaggcacg accgtccgta ccgcgcgcgt gcccaagtac
      841 taccgcttga agaagcacct gctcgacatg acggagacgc aggcgccggg cacgccggtc
      901 ccgcccgagc gcaccctggc cgccgagttc gacacctccc gcaccacggt ccgccaggca
      961 ctccaggaac tcgtcgtgga gggccggctc gaacgcatcc agggcaaggg caccttcgtg
     1021 gccaagccca aggtctccca ggcgctccag ctcacctcct acaccgagga catgcgggcc
     1081 cagggtctgg agccgacctc gcagctcctg gacatcgggt acgtcacggc cgacgaccgg
     1141 ctcgccgggc tgctcgacat caccgccggc ggtcgggtgc tgcgcatcga gcggctgcgc
     1201 atggccaacg ccgagccgat ggcgatcgag accactcatc tgtcggccaa gcgcttcccg
     1261 gccctgcggc ggtcgctggc gaagtacacc tcgctgtaca ccgcgctcgc cgaggtctac
     1321 gacgtgcacc tcgccgaggc cgaggagacc atcgagacct ccctggccac cccgcgcgag
     1381 gccgggctgc tcggcaccga cgtgggcctg ccgatgctga tgctctcccg gcactccctg
     1441 gaccgtggcg gcgatccggt ggagtgggtg cgctcggtgt accgcgggga ccggtacaag
     1501 ttcgtggcgc ggctgaagcg gcccgtggac taggagccgg ggtacgttcg ctgaatcgat
     1561 ataccgatat gcggacgagg tcttccactg gtacgacgac gtcacctaga ttgcctgcgc
     1621 attacccagg tgatcagtga ggggacggag ccgtggcatg tccgaaacgc ctgaagtgag
     1681 gccaccggtg gtgacaccgg tcagggtggt catcgccctg tgtctcgtcg cgcccttcgt
     1741 ggcgatgctg tgggtcggct cgtacgccga gacggatccc acgttcgtcg ggatcccgtt
     1801 cttctactgg taccagatgc tctgggtgct gatctcgacg gcgctcacgg tcctcgcgta
     1861 ccagctttgg cagcgcgacc agcgtgcccg cagcaggtcc gccgccggcc gggacgagga
     1921 ggcggcgaag tgaaggacgg cgtcaacggc gtcgcactcg gcgtcttcat cttcttcttc
     1981 ctggccgtca cggtcatggg cttcctggcc gcgcgctggc gcaggaccga caacgagcag
     2041 tccctggacg agtggggtct gggcggccgg tccttcggca cctgggtcac ctggttcctg
     2101 ctcggcggcg acctgtacac ggcgtacacc ttcgtggccg taccggcggc gatctacgcg
     2161 gcgggcgcgt ccggtttctt cgcggtgccg tacacgatcc tggtgtaccc gctgatcttc
     2221 accttcctgc cccgcctgtg gtcggtctcg caccgccacg ggtacgtcac gacctccgac
     2281 ttcgtgcgcg gccggttcgg gtcgaagggc ctgtcgctgg cggtggccgt gaccggcatc
     2341 ctggcgacga tgccgtacat cgcgctccag ctcgtcggca tccaggccgt gctggacgtg
     2401 atgggcgtcg gcggcggcga gaacaccaac tggttcgtga aggacctgcc gctgctgatc
     2461 gccttcggcg tgctggcggc gtacacctac tcctccggcc tgcgcgcccc ggccctgatc
     2521 gcgttcgtga aagacacgct gatctacatc gtcatcgcgg tggccatcat ctacatcccg
     2581 gtcaagctgg gcgggttcga cgacatcttc gccaaggccg gcgagaagtt ctccaccacg
     2641 ggcgtgggcg gtgtcgtgcc ggcccccgcg ggccagtgga cgtacgccac gctggccctc
     2701 ggctccgcgc tggcgctgtt catgtacccg cactcgatca ccgcgaccct gtcgtcccgg
     2761 agccgtgagg tgatccgccg caacaccacg atcctgccgc tgtactccct catgctgggc
     2821 ctgctggcgc tgctgggctt catggcgatc gcggccgggg tgaaggtcac caacgggcag
     2881 ctcgcgatcc cgcagttgtt cgaggacatg ttcccggact ggttcgcggg cgtggccttc
     2941 gcggcgatcg ggatcggggc gctggtgccc gcggcgatca tgtccatcgc ggcggcgaac
     3001 ctgttcaccc gcaacatcta caaggacttc atcaagccgg acgccacgcc ggagcaggag
     3061 acccgggtct ccaagatcgt gtcgctgctg gtgaaggtgg gcgccctggt cttcgtcctc
     3121 acgatggaca agacggtggc catcaacttc cagctcctgg gcggcatctg gatcctccag
     3181 acgttcccgg ccatggtcgg cggcctgttc acccgctggt tccaccgctg ggcgctgctc
     3241 gccggctggg cggtcggcat ggtctacggc acggtggccg cgtacgggat cgcctcaccg
     3301 acgcagaagc acttcggcgg cagcgccaag gagatccccg gcatcggcga gatcggctac
     3361 atcggcctca cggcgttcgt cctcaacgtc ctggtgaccg tggtcctgac cttcgtcctg
     3421 aaggccgtca aggctcccga gggcatcgac gagaccaggc ccgaggacta cacgtccgac
     3481 gcgggcgacc cgggcgtaca ggtggagctg ccgccggcca ccgcgggcgc cagtcactga
     3541 gcatcccgcg cagagcacgg cacaccccag ggggccgccg gaggtcacct tccggcggcc
     3601 cgccgccgta cccgtacccc tcgcgggcca ccgccgcacg ccctcccccg gcgggccgcc
     3661 gccgtgcgcg tccgccctcg gcgaccggtc ccggcaggac caccccccac cggcgtgagt
     3721 cggcctccga cgccgggccg acacaacatc tgggggtgag acgacagccc ggcaccagat
     3781 gtatgctcat gctcgctgtc gccgcagggg aatccggtgt gagtccggaa ctgtcccgca
     3841 acggtgtact cgcgtgcatc cgcacgcctg ttccagtccg aggtcctgcc gacagcgcac
     3901 ccggccgtcc ggtccgggtg cctgtgacgt ccgggcctcg tggagtgggc cggtggacgc
     3961 gacgccgtgt gcgctcgtgg ctgcccctgc cctccgccag gccccctcac cgagcgaggg
     4021 agagccccac gtgaccatcg cgccagccga cccggcttca gtcaccgagc tgaagaccga
     4081 cggtcccggt accgcgctgc tgcggaccct gaccgagctg accgccgacc tgcccgacgc
     4141 cgaccccggc cgggtcgccg ccgccgcact gcgcggccgg tccgcgcggg ccgacgaggc
     4201 ggagctgcgg gagctggcca cggaggccgc cgccggcctg atctccgagg accccgcgta
     4261 ctcgaagctg gccgcccggc tgctgaccct cgcgatccgg gacgaggccg cctcgcaggg
     4321 cgtgacgtcc ttcaccgggt ccgtcgcggt cgggcaccgc gagggcctcg tcgccgaccg
     4381 caccgccgcg ttcgtccggc tccacgccga gcggctcgac gcgctggtcg acggcgcggc
     4441 ggacgaccgg ttcggctact tcggcctgcg caccctgtac agccgctacc tgctgcggca
     4501 cccgatcacc cgcaaggtcg tcgagacgcc ccagcacttc atgctgcgcg tggcgagcgg
     4561 cctggccgag gacgacacga gccgggccgt ggacgaggtc gcggcgctgt accggctgat
     4621 gagccgcctg gactacctgc cctcctcccc caccctgttc aactccggca cccggcaccc
     4681 gcagatgtcg tcctgctatc tgctcgactc cccgctggac gagctggact ccatctacga
     4741 ccgctaccac caggtcgccc gcctgtccaa gcacgccggc ggcatcggtc tgtcgtactc
     4801 ccgcatccgt tcgcgcggtt cgctgatccg ggggaccaac gggcactcca acggcatcgt
     4861 gccgttcctg aagacgctgg acgcctcggt ggccgcggtg aaccagggcg gccggcgcaa
     4921 gggggcggcg gcggtctacc tggagacctg gcactccgac atcgaggagt tcctggagct
     4981 gcgcgacaac accggcgagg acgcccgccg cacccacaac ctcaacctcg cgcactgggt
     5041 gccggacgag ttcatgcgcc gggtcaacgc cgacgagcag tggtcgctgt tctcccccgc
     5101 cgaggtgccc gagctggtcg acctgtgggg cgaggagttc gacgccgcct accgccgggc
     5161 cgaggcggcc gggctggcca ggaagacgat cccggcgcgt gacctgtacg gccggatgat
     5221 gcgcacgctc gcccagaccg gcaacggctg gatgacgttc aaggacgccg ccaaccgcac
     5281 cgccaaccag accgccgagc cgggcagcgt catccactcc tccaacctct gcacggagat
     5341 cctggaggtc accgacgacg gcgagacggc cgtctgcaac ctcggttcgg tcaacctcgg
     5401 cgccttcgtg cgcgacgggg acatcgactg ggagcggctg gacgagacgg tccggacggc
     5461 cgtcaccttc ctcgaccgcg tggtggacat caacttctac ccgaccgagc aggcgggccg
     5521 ctccaacgcc agatggcgcc cggtcggtct gggcgcgatg ggcctgcagg acgtcttctt
     5581 caagctgcgc ctgcccttcg actcacccga ggccggggcc ctgtccacgc ggatcgccga
     5641 gcgcatcatg ctcgccgcgt acgaggcctc cgccgacctc gccgagcgca acggcccgct
     5701 gcccgcctgg gagcgcaccc gcgccgcccg cggggtgctc caccccgacc actacgacgt
     5761 cgacctcacc tggccggagc ggtgggacgc gctgcgcgag cgcatcgcgt cgacgggcat
     5821 gcgcaactcc ctgctgctgg ccatcgctcc gacggccacg atcgcctcga tcgcgggggt
     5881 gtacgagtgc atcgagccgc aggtgtcgaa cctgttcaag cgcgagacgc tctccggtga
     5941 gttcctccag gtcaactcct acctggtgcg ggagctgaag gacctcggcg tgtgggacgc
     6001 ccgtacccgt gaggcgctgc gtgacgccaa cggctcggtg cagggcttcg cctggatccc
     6061 cgaggaggtg cgcaggctgt accgcacggc ctgggagatc ccccagcgcg gcctcatcga
     6121 catggccgcc gcccgcacgc cgttcctcga ccaggcccag tcgctgaacc tcttcctgga
     6181 gacgccgacc atcggcaagc tctcctcgat gtacgcctac gcctggaagt ccgggctgaa
     6241 gacgacgtac tacctgcgct cgcgccccgc gacgcgcatc gcccgcgccg cccaggcgca
     6301 gcccgccatc cccgtgcagc aggccgccga ccccgacgcg gtcgcctgct ccctggagaa
     6361 ccccgagtcc tgcgaggcct gccagtaatg accacccgta ccacccggct cctcgacccg
     6421 ggcttcgagc tgacgctgcg cccgatgcgc taccccgact tctacgagcg ctaccgggac
     6481 gccatcaaga acacctggac cgtggaggag gtcgacctcc attccgacgt caccgacctc
     6541 gcccggctga cgccggagga gcagcacctc atcggccggc tggtcgcctt cttcgcgacc
     6601 ggcgactcca tcgtcgcgaa caacctggtg ctgacgctct acaagcacat caactccccc
     6661 gaggcgcggc tctacctgag ccggcagctc ttcgaggagg ccgtccacgt ccagttctat
     6721 ctgaccctgc tggacaccta cctccccgac ccggacgacc gcgccgccgc cttcgccgcc
     6781 gtcgagaaca tcccctccat ccgggagaag gccgggttct gcttcaagtg gatcaacgag
     6841 gtggagaaga tcgaccggct ggagacccag gccgaccgcc gccgcttcct gctgaacctg
     6901 atctgtttcg ccgcctgcat cgaggggctg ttcttctacg gcgccttcgc ctacgtctac
     6961 tggttccgca gccgcggtct gctgcacggc ctggccaccg gcaccaactg ggtgttccgc
     7021 gacgagacga tgcacatgtc cttcgcgttc gaagtcgtcg acaccgtccg caaggaggag
     7081 ccggagctgt tcgacgacgc gctgcggcag gaggtcacgg acatgctcgg ggaggccgtc
     7141 gaggccgagc tgcagttcgc ccgcgacctg tgcggtgacg gcctccccgg catgaacacc
     7201 gaatccatgc gccagtacct cgagtgcgtc gccgaccagc gcctcacgcg cctcggtttc
     7261 gccccggtgt acggctcgca gaaccccttc tccttcatgg agctccaggg tgttcaggag
     7321 ctgacgaact tcttcgagcg ccgcccgtcg gcgtaccagg tggcggtgga gggcacggtc
     7381 gacctggacg aggacttctg atccctgctg tctccccggg cctcctgggc ctgcctgagc
     7441 tgccggtcga tgcgccgctc gcgcacgacg ccgagcacgg acgggaggac caggaggacc
     7501 aggatcccga gggtggtgcc cattccgatg agaccttcga tctggtttcc gttcatggac
     7561 accactctcg cgccggacac tcctgaccgg gagtggcagg actgccgtag accctcgaat
     7621 tactgccaat ggtggggcac actggcagca tgctgaagaa cgtggccgtc gtgctgctgg
     7681 acggggtgca gcccttcgag ctgggtgtcg tgtgcgaggt gttcggcatc gaccgcagtg
     7741 acgacggact gcctgtgtac gacttcgccg tggtctctgc ggaggggccc tcgctcggca
     7801 cccactgcgg gttcaccgtg tccacgccgt acgggctgga gcggctggaa gaagccgacc
     7861 tgatcgccgt accggccggg caggcctacg cggagcgcgc gttccccgag gagctgctga
     7921 cggcgctgcg gcgggccgtc gaccggggca cccgggtgct cagcgtctgc tccggcgtgt
     7981 tcgtgctggc cgcggcgggg ctgctggacg gacggcggtg tgcggtgcac tggcaccacg
     8041 ccgagcagct cgcccggcgc tatccccggc tcgaggccga gccggacatg ctctacgtgg
     8101 acgaggaccc ggtcatcacc tccgccggca cggccgcggg catcgacgcc tgtctgcaca
     8161 tcgtgcgcaa ggagcagggc ccggaggtgg ccaacaagat cgcccgccgg atggtggtgc
     8221 cgccgcaccg ggacggcggg caggcgcagt tcatcgagcg ccccctgccg aaggctccct
     8281 gcgacacggt cggggaggtg ctggcgtgga tggaggcgca cctcgaccag gaggtgaccg
     8341 tcgaacagct cgccgcccgt gcccacctgg cgccgcgcac cttcgcccgc cgcttccagc
     8401 aggagacggg gaccactccg taccggtgga tcctgcgcca gcgcgtgctg ctggcccagg
     8461 agttgctgga gggcacggac gagaccatgg acgccatcgc cgggcggacg gggttcggta
     8521 cggccgcggc gctgcgtcat cagttcgtgc gggcgctggg gacgaccccc caggcctacc
     8581 ggcgcgcgtt ccgcggcccg caggccgcct gagcacgcgc cggtaccggc ggcctaccag
     8641 ggcatcgccc gcagcagcag gttctgcggg cggagcgtga tgcccacgcg ggtgctctcg
     8701 tcggacccgg cggcccgctc gaagcggtac ttcgccgaga ccgccgcggt gatcaggctc
     8761 agttgggtca tggagaagtg gtcgctgggg cacttgcggt tgcccacgct gaacgggctc
     8821 atggcgtact tcggcacctc accggcgcgc tcgggcagcc agcggtcggg gtcgaagtcg
     8881 aggtggcggg cgtaggaacg ggcgtcgcgc tggatggcgt acgggctgtg gacgatgtcc
     8941 gccccggccg gaatgcgata gccgccgagt acggcgtccg tcgtcgcgcg gcgcgtcaga
     9001 atccatacgg cgggcctgag ccgcatggcc tcgacgacga cattgctggt gtgcttcagg
     9061 gcacgcacgt gctcgaatcc gaccggccgg ccaccggtca cggattcgac ctcggcccgt
     9121 accctctcgg cgtgttccgg atgcgcggcg agggcctgga gcagccacat gaccgtggac
     9181 gccactgttt cgctgccggg ggtgaggatc gcgacgacct ggtcgtggat ctcctgttcc
     9241 ccgatgggct cgccattgtc gtccttcgcc tccagcaatg ccgtcagcaa atcgtccggc
     9301 ttttgaccag atgcccttct ctcggcgacg atctcgtcca ccagcagatg cagatcggcc
     9361 aacgcccggt tgaattcccg gttggccgga aacggcagcc ggtagagcgg acccagcggg
     9421 atcaccatcc tgcggtacat accgcggaag acggtggcga gatcggtgct gagccgttcc
     9481 gcgcgctcgt ccatgtagtc gccgcgcagc aggcagcggg cggcgatacg gacggcgacc
     9541 cggaaggact cggaggtgca gtcgatggtc tccccgggtt tccagcgctc ggtgagccgg
     9601 tgcgcctcct cctccatgac cggcccgtac tgcggtatcg cgtcgagccg gaacgcgggc
     9661 tggatggtgc gccgctggcg gcggtgccgg gagccgttgg cggtggccac gccctccttg
     9721 ccgagcaggc cctcgaggga ctcccacagg gggccggcga tgctgaagcc ggggctgagg
     9781 gccagggctc cggtgagcgc cggcgcggtg acggcgtaca ccgtcttggg gccgagccgc
     9841 aggcgcacga tgtcgccgtg gtcgcgcagc ccggacatga aggcgagcgg gtcgcggacc
     9901 agtttcaggc cgtgtccgag gaccggtacg gcacccgggg ccaggggcgg ttcacgcagt
     9961 gcggtcgttc tgggggtcgc gggcttcacc gactcgacgg tcatttctca cctgccgctt
    10021 cgttcgtcac gtacgggggc gtggaccggt cgtcccagtt gtcgaccatg taccggccgg
    10081 actcgtggtg gaaccagtag acggagctga accagttgcg catggcgtcg acgcacgtgc
    10141 ggacggcggc gccgagctcc gcgccgcggg cggttccgtc gtcgatgtcg tgggcgagcc
    10201 gcagggcgtc ctgttcggcg tccagaaatt caccggcgca ttcctcgacg cgccgcctga
    10261 cgtcgtccac cgcttcttcg agggtcagcc cctcatgggt gatgaggctg atcccgagat
    10321 tgtggacctc gtcgccggct atttccttcg gcagcgagca aaggtcgttg taccaggcgg
    10381 cgaattcctg actgaggagg gccgcccggc gataggccgg gtttttccgt acggcgtccg
    10441 ggagttcgca tccggcactg ggttcgagca gatccgtcca tatccggtgg gcgaaggtca
    10501 ggcggcgcag ggcgagatat tcctcgacgc cgggcacgta tccttcggtg cggttgcgga
    10561 attcgcggtc ataggcctcg atcaccgcgt ggaaatgcct ggcgaaccgc aggttccagg
    10621 tgcgtgacag gaggccgtac agccgcagca cggtgtcggc gaagccggcg accagtgggt
    10681 ccgggtggtg cacgtggtgc ccgggcgcgt cgagtgccgc gtgcagccgg tgtctcagcc
    10741 gccgccagtc gcccgcccgg ccgtgcacga tgtcacggtc gtggcggtcg tcccagacga
    10801 agaaccacgc gctgtagtcg gctatggcct ggaggacctc gtcggcggcg ctggtgtagt
    10861 agccggccat gaggtccgtg tagcacagtc catcggcata ttcatggacc ttgtccgccg
    10921 gcatcagccg cttttccagc agccacagcc gcgtgttctc ctggagccgc ggccaatacg
    10981 gatgcagtcg ccggggaaaa gcggactcga tcaccgggag ggccagtgag ggcgggacca
    11041 cgaccgccgt ccgggtcact gtggtgctgc gtgggaaagc ctgcacgtac aaaccccttc
    11101 cagccgccag gagcgcacgc ccctcctgct gtgccgggcg tgcgccgttg cgtatccccg
    11161 tacttccatt cagcaccaca agtgaccgcc atgggaacgg atttgcacca ttcactaccc
    11221 cacggtgccg agaatccccc ttgtgtgact gattaaggat caccagggtc ccgcaaggga
    11281 tcgggtgtac gacgcacggg cgaacgagga gcggcaacgc gaaggcgccc ggccgggacg
    11341 gatcccggcc gggcgcccat gtgccctgcg ctggtcagtc gttggcgacc acggggtagc
    11401 gcggctcgtt ctcggccatc tgccgcagcg cgtccttgcg gtcccgcttc gacagccggt
    11461 cgatgtacag gtggccgtag aggtggtcgg tctcgtgctg caaacagcgt gcgaagtagc
    11521 cggtgccgcg gaccttgacc gggttgccct gctcgtcctg gccggtcacc tcggcgtagt
    11581 cggggcgcgc gagcgacgcg taggccgtcg gcacggacag gcagccctcg ttgctgtcgt
    11641 ccagccggcg ctgctcggcg ggcaggtcga ccagcttcgg gttgcagatc acgccgacgt
    11701 ggcgggcgcc ctcgtcgtcc tggcagtcgt agacgaagac cttcaggtcg acaccgatct
    11761 ggttggcggc caggcccacg ccctcggcgg tgcgctggct ggcgaacatg tcggcggcca
    11821 actgctgcag ctcctcgccg aactcggtga cgtccctgca ctccttgtgc agcaccgggt
    11881 tgccgacgac cgtgatcggc cgcgaggtcc cgcgctcgcg ccaggcctgc tcgcgctcct
    11941 cgcagtcctc cgtgtcgacg acgtacccct cgtcgtcgac ggggagcacg cccgcgtgct
    12001 gctgatcggt gtcctggtgc gccatgaccg acgtacgcct tcctcaaaga acagggggga
    12061 gatgttgctg atacagggta cggcgaccgg tcagcagacc tcttccagat cccgccagtc
    12121 ccgcgagtcc gggctgtcct ggacccatcc gtccagcagc ccgcgcacga gcgaggccgg
    12181 cgccgcgacc ccgcactccc gctcgggcac ccacaactgc ccgtccgtcc ggtgccccag
    12241 cggcccggga tgccccggct cgctgtggtc gtgcgggtcc aggtgcaccc cctcgccctc
    12301 gtcggacggc atccgcgact ccgagcacgt ccggcacagc agccgcaccg acgacgacca
    12361 gtcctccgcg gcgaacccgg cgtcggcggc gagccgctcc aacgcgtccc ggtccgcctc
    12421 cgtggccgcc tccagcagga ccacccaggt ggggacgggt gacggtgccc acagctcgat
    12481 ctcgtcgaag accgggtagg tgtgcccggc ggacgtcgtg cgctcgccgt gcgggagacg
    12541 ccgtcgtgca gcacgacctc gccccagcgc cgcccggacg agggcagcgg gatggacagc
    12601 acctccatcc gcgccgggtc cagcctgcgg ccccacacga cctcggcctc gccctccggg
    12661 gacagccgta cggccgcgct gcccagctcc atgccgagcg gctcaccgga gacggcggca
    12721 ccgccgggca ccttcagccc gtacgcctgc caggcgcggc gggccagcgg ccagtcctga
    12781 agggcggtcg cggcgatccc cacgttccac cagtccgggg cgccggcctc ccggtcgagc
    12841 agggcgaccg cgcgcagacc ggcggcgcgg gcctgctccc agtcgtgccg gaacttgtgc
    12901 agcagggcca ggttgaacca ggactccgcc agccagggct ccaggtcggc ggcgcgtgtc
    12961 agcagctcgc ccgcgtcctc gtaccggccg tcgccgataa gtgtgaacgc gcggtctgtg
    13021 gcctgccgcc aggaggcgga gggccggtgc cgtgccttgc cgaagatcct cacgattccc
    13081 gcctgccagt tccatttccc gctgtgggct ggcttgtgcc cccggacacc ctctccctcg
    13141 catccaacca cgtacggcgg gagagtcgct cattacccat gggttaccca gccgggagcg
    13201 gggtcagaca gtcccgttcg tctcgcaccg gcgtcggccg ggacggtcgc gcgccagccg
    13261 cggggccggg ccaggacccg ggcgagcgat tccacgacct ccggagcgta gtcgtcggcg
    13321 gtgcccagcc gcagctcctc cagcgcgtgc agcgggccct cgggaccggc gtcccgggcc
    13381 ttctcctcgt aggcgttcac ggtgcgcacg atccgggcgg cgagcggctg ctccgggcag
    13441 gggtcggcct gccgctccac gacgacggcg acggccgcgt ccacgccggt ctgccggacg
    13501 acggccccgc cgagcagggc gatgcggcgt tgctcggcgg cgggcaggac ggcggtggcg
    13561 cccgccggga ccgggtcgac caggctgagc tgaccgatgt cgtgcatgag cgccgcgtac
    13621 tccaggacgg tcagctcggg tccggtcagg ccgaggtcgc ggccgacggc gaggctgagc
    13681 gcggcgaccc ggtgggcgtg cccggcgggg gtgcagccgg cgatctcggt ggcgcgggcc
    13741 agggaggcga tggtctgccg gtaggtggcg cggacggccg cgtaccggcg gagggacacc
    13801 tggacgagga gcagcggcag acagaacacg ggcagtgccc acagcccggc gacggcgacc
    13861 gcgagcgcca tcacggcgcc ggtggcacag accgcggagc cgatgccgag cagtccgcgc
    13921 agttcctcgc gcagcagcgg accgaacggc cggccgctgc ggcagtgggc gagcgtggcg
    13981 gccaggacgg ccccgcacag ggaggtgagg gcgagcaggg tgaggagcag cagggggtag
    14041 gcggggccgg tccaggaggc gaacacccgg ttgtcgtaag ggggttggaa gcagagggcg
    14101 gcgaagccga cggtgaggac gcggcgggcc aggtggtcgg cggtcggggt gccgccggac
    14161 cagatgtgcg ggacggcacc gaggagggcg gcgacgagga ccacggtgac gacctgggcc
    14221 gcgccgtgct gggcgggccg cccggcgtcg gcgcccagca gcgcgtacga cagggagccc
    14281 gcggcgccca ggggcgcggc ctgccgttcc tgggcgtcgc tccaccgggt cagctcgccg
    14341 acggcgatga gcgtgccgaa ggcgagcgcg acgccccggt cctccagacc ggtccacagg
    14401 gtgacggcga gggagccggc cgcgacgagg acggcggcgc cgtggatgag ccgcagggga
    14461 ctcaccgggc tgccccggtg cggggggccc gctcggcggg tgtcatgacg tacgcgggtt
    14521 cgtcggcggt gaccgtgggc cgccagccgc agcggcgcac ggcgcggacg agggcgccga
    14581 ccatccgggg gtcgaagtgg gcgcccgcgc agcgctccag ctcggtgacg gccgcctcga
    14641 ccggccgggc cctgctgtag gagcgggtcg aggtcatcgc gtcgaaagcg tcggcgacgg
    14701 cgacgatccg ggcgcactcg gggatctggt caccggccag gccgtacggg tagccgctgc
    14761 cgtcgagccg ctcgtggtgg tggaggatcg ccgcgcgggc ctcaccgagg aaggagatcc
    14821 cgcggaccat ctcgtggccg tactcgggat gcagctcgat gatccgccgt tcctcggggg
    14881 tgagcggtcc gtccttgcgc agcagccggg tgggcacgcc gagcttgccg acgtcgtgca
    14941 ggatgccggc gaagcgcagc gtctcgacgc ggtcgtcgtc catgccgagt tcgcgggcga
    15001 tcagcacgga ggcctggccg acgcgttcgc tgtggccgcg ggtgtagccg tccttgatgt
    15061 cgacggcctg gacgagggcg cggatggtgg cctggtgggc cgcgcgttca cggtggtact
    15121 gggcgaacac ccagcaggag acgcacatcg ggagcaggac gagcagcgcg gcggacggac
    15181 cgtacggact tcgccagagc acggccatca tcagtccggc gaggccgtgc acggcgacgg
    15241 gcgcgaggga gcgggccagc agcccgcgcc aggcgcgccg cggcggcacc agcccggccg
    15301 ccgcccgcag gccgccgtcg agcagggtca gcacgaggca gaggacgagg acggcggcac
    15361 cggcgggcag cagggcgtag gggaagtcgg agccgacgac ggcgtcccgg ccgccgagcg
    15421 cccggtgcac gtgggcggcg ccgcacacgg cgagcgcggg ccgcacggcc cgccacacgc
    15481 gccgggacag ggcggcccgg tgcccggccg gggggagcag gagggcgggc agcgggacga
    15541 gcgcggcggc cggcgggggc agcaggaagg ccccggcgag cagcacgggg tagaaggtgc
    15601 catcgagacg ccggcgcacg acgtgctcac aggccgcgta gagggcggcg aggagacacg
    15661 gctcccacca tgggacatgg ctggtcggca ggcgcagcag gcagagggcg gcgagcaggg
    15721 cggcggcggc aacacagccg cgtgctctcg ccggtaccgc gtccatcacg cccctccccg
    15781 accctgcccg tcccggctgg gagcctaggg cggaggtcgg ggggtgcggg ggcttatgac
    15841 ctgaggatta gcacgttcgg gtgatacgac ccggcgtgtc aggattcctg gggcgccgtc
    15901 ggggtccggg tcacgtcgtg cccgggcacg gtctggccgg agcggatcag gtcgatccgc
    15961 cccatgacct tggcgcgcag gtcggcgggc acgtcgtcat ggccgcagca ccgcttgacc
    16021 agcttcttca cggcctgctc caggccgtac ttctccaggc acggcgagca ttcctcgaag
    16081 tggtgctgga acttgtcgcg gtcgacgtcc ggcatctcgc tgtcgaggaa ctcgtacagg
    16141 tggtccagaa cctcactgca gtccgtctcg tgcggctctc cgcagctcat gagcccgagc
    16201 ctttcgcttc gttcgactct ccggcaccgg ccgggaccag accccgctca cgggcgtagt
    16261 cctccagcat gccgcgcagt tgacggcggc cccggtgcag ccgggacatc accgttccga
    16321 tgggtgtccc catgatgtcc gcgatctcct tgtacgcaaa gccctcgacg tccgcgagat
    16381 acacggcgat gcggaactcc tcggggatcg cctggagcgc cgacttcacg tccgagtcgg
    16441 gcaggtggtc gagcgcctgc gactcggcgg agcgcaggcc cgtcgacatg tgcgactcgg
    16501 cgcgcgcgag ctgccagtcc tcgatctcct cggccgcgct gcgctggggt tcgcgctgct
    16561 tcttgcggta ggagttgatg aaggtgttgg tgaggatgcg gtacagccac gccttgaggt
    16621 tggtgccctc gcggaactgg tggaaggacg cgtacgcctt cgcgtacgtc tcctgcacca
    16681 ggtcctcggc atcggccggg ttgcgcgtca tgcgcagcgc ggccgagtac atctggtcga
    16741 ggaactcgag cgcgtcccgc tcgaagcgcg cgctgcgctc cacggtcgtc tcaccggacg
    16801 cctccgcgct gacgccctgg tcctcgggcg gccccgcctg gccgttgtcg gtccctgcgt
    16861 cggtcccagt gaccggaccc acctcctcga agttccgggc gggaccggaa acggtcccac
    16921 tcgtttcgga ggatagaaca cgacccgtgc ctgccgccgc tcgaatagga gcggtcctgg
    16981 ccgcgtgcag caccgtccag tccaggtcag tacggctgct gcggcccggg cagatggtcg
    17041 aacccatgcg gcggacttcc tttcccacga catcggtgcc gaggcgtcag cacttctgtc
    17101 ccccacaaca gcgggttgcc gcgcggcatt ccctgccgtc acccgagtga cagggtccac
    17161 tcggcgaccc gggctccgac gaggtccagg gcctgttcct gtgtgaggtc cgcgcgccgg
    17221 ggtaccgcga gaccgtgatc ggcgtggggc acctcgacca ggtcgaaatc gcccgccggg
    17281 aactcctccg gcctgccgaa ggggtcgttc ccgccctgca cgaccagcgt gggcaccccg
    17341 gtgcccagca gctccccggc gcgggagcgc tccggcctgc ccggcgggtg cagcgggaag
    17401 ctcagcgcga gcacggcgtg cgcgcccagc tcggcggccg tacggcaggc gacgcgggca
    17461 ccggcgctgc gcccgccgga gatcaccggc aggccgggcc gggcgagcgc gggccacacc
    17521 ccgcgccatc cggtgtccag ggtcttcggg gcgggcgcga ccttcttgcc cgcgacccgc
    17581 cagggctgct cgacgagggc gacggtgaca ccccgcgcgg gcagtgtccc ggccagtacg
    17641 tgcaggtccc gggcctcgat gccgccgccc gcgccatggc tgacggccag caccaggcgg
    17701 gcctcgcgcg ccgggtgcca ggtgatccgg gccggtccgg cgtccgtgtc gacggtctct
    17761 gtgttcacgt cagaagagtg tgccctcttc cggtgcctga agctccttca gcagctccgg
    17821 gccgttgttg cggacgttgc tgacggcggt ggagaccggg taggcgcgca tcaggccggg
    17881 cgggggcggg gccagcaggg cgcgcagctc gtcggggtcg gtgcgggagg ggtcgagcca
    17941 ggcgtcccag cggtccgggg tgagcatcag cggcatccgg gggtggatgt cggcgaggga
    18001 gcgcgggccc tcggcggggg cgacggccag cgggtcccgc tccgcctcgg tggtgatcac
    18061 cgagcaggtg gcccaccagg cccgcgggtg gtcgtcgggc agcgtccggt cgcgccagaa
    18121 ctcgtacagg ccggccatcg cgaacaccga gccgtcggcg gggagcacga agtacggctg
    18181 cttgcgcggg cgcttcttcc tgccctccac ctccagctcg cgttcctggc tgccggtgac
    18241 ccactcgtag tagccgtcgg cgggcaggag gcagcggcgg gcggcgaagg cacgccggta
    18301 ggcgggcttc tcgtgcacgg tctccgcgcg ggcgttgatc atccgcgcgc cgccctcggg
    18361 ggtcttagcc caggacggga ccaggcccca cttgagcctg cgtagctgac gaaccggacg
    18421 cggggagtcc gcgtctttca gggggcggtc cagtacggcg tggacctcct tggtgggggc
    18481 cacgttgtag tccggctcca gggtctcctc gggatcccag tgttcgacct cgaagactcc
    18541 cgcgagatcc tcgggcccac gactcgatgc ataccgtccg cacatacgtg ccacactgcc
    18601 aggccgaccc gtcacccgac caccacccca ccacgacggc gcccccgcgc cgacccccga
    18661 cgatcaccag gacagggagc cactcggaca catggacagc ctcgccgcca ccgcgctgcc
    18721 cggcctctgg gaccgcctca ccggcaccca gcccgatccc ggcctgtggg tgatcctggc
    18781 caccctggcc gcggcgctcg ccgtcgtcgt cccgcacccg gtgtggcgga tatcccgcaa
    18841 cgcgatcacc atcgcgcacg agggcggcca cggcctggtc gccctgctca ccggccggca
    18901 gctcaccggc atccggctgc actccgacac cagcgggctc accctcagcc ggggcaagcc
    18961 gtacggactg ggcatgatcc tcacggccgc ggccgggtac acggcgcctt ccctgctggg
    19021 gctcggcggg gccgcgctgc tggccacggg gcgcatcacc ctcctgctgt gggtggccac
    19081 ggccctgctg ctcgcgatgc tgttgatgat ccgcaacgcc tacggcgtcc tcaccgtggt
    19141 gctggccggg ggcgcgttcc tgttggtgtc ctggctggcg gggccgcagg tgcaggcggc
    19201 gttcgcgtac gcggtggtct ggttcctgct ggccggcggg gtacggccgc cgttcgaact
    19261 gcaggccaag cgggcgcggg cgggcgcggg cgactcggac gcggaccagt tgtcccggct
    19321 ggcgcacgta ccggcggggc tctggctctt cctgttccac gcggtgtccc tgtcctcgct
    19381 gatcggcgga ggccgctggc tgctggaagg ttgacgccgg gccctgctta taaagtgacc
    19441 ccatggcccc gaaccccgcc cccaccgccc cctggcccgc cccgcacgcg agcggggccg
    19501 tcgacgccac ggtccacgta ccggggtcca agtcggtcac caaccgcgcc ctggtcctcg
    19561 cctccctggc ctccgaaccc ggctggctgc gccgcccgct gcgctcgcgg gacaccctgc
    19621 tgatggccgg cgcgctgcgc gcgatgggcg tggagatcga ggagggggtg ggccccgacg
    19681 gcaccggtga ggcctggcgg gtgctgccca cgggcctgcg cggcccggcc acggtcgacg
    19741 tcggcaacgc gggcacggtg atgcgcttcc tgccgccggt ggccgcgctg gccgacggtc
    19801 cgatccggtt cgacggggac ccgcggtcgt acgagcgtcc cctccacggg gtgatcgacg
    19861 cgctgcgggc gctcggcgcc cggatcgacg acgacggccg gggcgcgctg ccgctgaccg
    19921 tgcacggcgg cggcgccctg gacggcggcc cggtctcggt cgacgcctcc tcgtcctccc
    19981 agttcgtctc cgcgctgctg ctgtccggcc cgcgcttcaa ccagggcgtc gaggtccggc
    20041 acaccggtgc caccctgccg tccctgccgc acatccggat gacggtcgac atgctgcgcg
    20101 cggtgggcgc ccaggtggac accccggagt cgggcggcga gcccgacgtg tggcgggtga
    20161 cgccgggggc gctgctcggc cgggacctga ccgtcgagcc ggacctgtcc aacgcgcagc
    20221 cgttcctggc ggcggccctc gtcaccggcg gcaaggtgct cgtcccggac tggccggccc
    20281 gcaccaccca gccgggggac cggctgcggg agatcttcac cgagatggga ggctcctgtg
    20341 aactcaccga ttacgggctc gtgttcaccg gttcgggcgc ggtccacggc atcgacgtgg
    20401 acctgggcga cgtcggcgag ctgaccccgg gcatcgcggc ggtcgcggcg ctcgccgact
    20461 cgccgtccac cctgcggggc gtggcccatc tgcggctgca cgagacggac cggctggccg
    20521 cgctcaccaa ggagatcaac gaactcggcg gtgacgtcac ggagacggcc gacggcctgc
    20581 acatccgccc gcgcccgctg cgcggcgggg tgttccacac ctacgaggat caccggatgg
    20641 cgacggccgg cgcggtcatc ggcctggccg tcgagggggt gcggatcgag aacgtggcga
    20701 cgaccgcgaa gaccctgccg gacttccccg cgttgtggac cgggatgctc gggcagtaag
    20761 gacgtaacag catgcgccgc tatggcaagc acaccgacga ggacgacatc cgcagccgcc
    20821 ccaaccgcaa gggcaaccgg ccgcggacca gcatccgccc caagcacgag gacgcggccg
    20881 agggcatggt cctcaccgtc gaccgggggc ggctgacctg cctggtgggc gaccgggtcg
    20941 tcctggcgat gaaagcccgc gagctgggcc gcaaggccgc cgtcgtcggc gaccaggtgg
    21001 ccctggtggg cgacctgtcg gggaagaagg actcactcgc gcggatcgtg cggatcgcgg
    21061 ggcgcacgtc ggtgctgcgc cgcacg
//
