LOCUS       NZ_CP033073            35865 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces dangxiongensis strain Z022 chromosome, complete genome.
ACCESSION   NZ_CP033073
VERSION     NZ_CP033073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces dangxiongensis
  ORGANISM  Streptomyces dangxiongensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     The genome of Streptomyces dangxiongensis Z022
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) State Key Laboratory of Cryospheric
            Sciences, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. version 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 213.0x
            Sequencing Technology             :: Illumina and Pacpio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003675325.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 04:16:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,241
            CDSs (total)                      :: 7,151
            Genes (coding)                    :: 6,614
            CDSs (with protein)               :: 6,614
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 537
            CDSs (without protein)            :: 537
            Pseudo Genes (ambiguous residues) :: 0 of 537
            Pseudo Genes (frameshifted)       :: 320 of 537
            Pseudo Genes (incomplete)         :: 281 of 537
            Pseudo Genes (internal stop)      :: 26 of 537
            Pseudo Genes (multiple problems)  :: 83 of 537
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:47:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2038038
            Orig. end                         :: 2073903
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033073.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Binglin Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..35865
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /product="butyrolactone"
                     /region_number="16"
                     /rules="IucA_IucC"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..35865
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="NI-siderophore"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..29953
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..29953
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:15953](-)"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(14001..15953)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     misc_feature    505..516
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     misc_feature    complement(567..578)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            599..2149
                     /locus_tag="D9753_RS09010"
                     /old_locus_tag="D9753_09010"
     CDS             599..2149
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385169.1"
                     /locus_tag="D9753_RS09010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09010"
                     /product="MFS transporter"
                     /protein_id="WP_121786531.1"
                     /transl_table=11
                     /translation="MTTSQLLQDDRKPGTARREGHPGIALTVIAACQLMVVLDATIVNI
                     ALPHIQDALKFSTTDLTWVVSAYTLTFGGLLLLGARAGDILGRRRVFMAGILLFTFASL
                     LGGLAQEPWQLLAARALQGVGGAIASPTSLALITTTFPEGPERNRAFGVFAAVSAGGGA
                     IGLLAGGMLTDWLDWRWVLFVNVPIGVLIASLAPLYINESRRHPGRFDLTGALTSTTGM
                     ATLVYGFIRAAEEGWRDALTLGSFAASAVLLFAFVFIEMRAKEPITPLRMFTDRNRWGT
                     YVIMLSLAAAMFGMFFYIVLFVQNVLGYSAIKAGVAFLPVTVAIAIGAGLSQRFLPAFG
                     PKPFMMTGSAFVVVGLTWQTLIRPDSSYVGGVLGPLLVFGFGMGLNFVTATVTAVSGVA
                     QHEAGAASGLLNAMQQVGGSLGLSILTTVFGSAGKDEAKKQLPKFLADGSPEQKAQFAK
                     THQLPAPWGHEVLAHGISTAFVPAAAMAVLAFLTAWLVIRVRKSDLDSLAGVAGPGIG"
     gene            complement(2493..3398)
                     /locus_tag="D9753_RS09015"
                     /old_locus_tag="D9753_09015"
     CDS             complement(2493..3398)
                     /EC_number="3.2.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004982580.1"
                     /locus_tag="D9753_RS09015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09015"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_121786532.1"
                     /transl_table=11
                     /translation="MTADSSSLERFERASASLRGLAVGDALGSQFFVPVNYPLLKRREL
                     PPGPWQWTDDTEMACSVVAVLAAHQRIDQDALARSFAEHHDFDRGYGPAVNRLLRLVRE
                     GGDWRELAAGLFNGQGSWGNGAAMRIAPLGAWYADDPEQATHQAEISAYPTHQHREAVV
                     GAMAVAAAAALAGSPDGPPSGEALLDGVIALVPKSAVGQGLRRARDMLDYGDPATVAAV
                     LGSGRRTTAHDTVPFALWSAARALGDYETAFWTTAQVGGDMDTTCAIVGGVLAAGKAGA
                     PPAEWVQRTEALPEWVSAGL"
     gene            complement(3411..4070)
                     /locus_tag="D9753_RS09020"
                     /old_locus_tag="D9753_09020"
     CDS             complement(3411..4070)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973214.1"
                     /locus_tag="D9753_RS09020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09020"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_121786533.1"
                     /transl_table=11
                     /translation="MARPRRIVLVRHGESTGNIDDSVYEREPDHALALTERGRRQAEET
                     GERLRQLFGRERVSVYVSPYRRTHETLRAFHLDSDLIRVREEPRLREQDWGNWQDRDDV
                     RLQKAYRDAYGHFFFRFPQGESGADVYDRVGGFLESLFRSFEAPDHPPNVLLVTHGLAM
                     RLFCMRWFHWTVAEFESLANPGNAEMRMLVLGEDGRYALDRSFERWREPVPYWVSG"
     gene            complement(4223..4828)
                     /locus_tag="D9753_RS09025"
                     /old_locus_tag="D9753_09025"
     CDS             complement(4223..4828)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1258: Antibiotic biosynthesis monooxygenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385166.1"
                     /locus_tag="D9753_RS09025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09025"
                     /product="YdbC family protein"
                     /protein_id="WP_121786534.1"
                     /transl_table=11
                     /translation="MLVKWIRCTVVDRRGFERGQRKWAGLPGEPGFRGQGGGWSRQRPG
                     VAHVFAFWESRAFYDSFMARSHDRLAAAQSGTFKDAQVRLFEYRFDVKTGFEPRFTDAD
                     LVRVALCRIHEERVEHFTLMQEKVWNPAMAGSPGMIRGMFAEAPEQEFLILSMWRSAAE
                     HGKYRTERIERLALRAQTEADVAALSGDIVELEPSWTV"
     gene            4982..5515
                     /locus_tag="D9753_RS09030"
                     /old_locus_tag="D9753_09030"
     CDS             4982..5515
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005481526.1"
                     /locus_tag="D9753_RS09030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09030"
                     /product="TerD family protein"
                     /protein_id="WP_121786535.1"
                     /transl_table=11
                     /translation="MTGFSKGLRKVEIALKWDPSPAGRPPTDLDIIAATFVSADAYGTP
                     AYLVHFDSRSPDGTIFLNRDSTDGRGFGWDEVMMLELERLDSRYARVVVGVVIQQGPGY
                     KTFADVLNPAVRVREGYTVLAEDDFASVLGATAATIAEFVRDDSGEWTLRPGVHGFDED
                     PATFTQVMGRARRP"
     gene            complement(5729..8632)
                     /locus_tag="D9753_RS09035"
                     /old_locus_tag="D9753_09035"
     CDS             complement(5729..8632)
                     /EC_number="1.17.4.1"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030467.1"
                     /locus_tag="D9753_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09035"
                     /product="vitamin B12-dependent ribonucleotide reductase"
                     /protein_id="WP_121786536.1"
                     /transl_table=11
                     /translation="MTETASGPARGSRAKGGKAGNKGLHIERIHTTPGVHPYDEVSWER
                     RDVVMTNWRDGSVNFEQRGVEFPDFWSVNAVNIVTSKYFRGAVGAPQREVSLRQLIDRI
                     VKTYRKAGEDYKYFASPADAEIFEHELAYALLHQIFSFNSPVWFNVGTPQPQQVSACFI
                     LSVDDSMESILDWYKEEGMIFKGGSGAGLNLSRIRSSKELLSSGGNASGPVSFMRGADA
                     SAGTIKSGGATRRAAKMVVLDVDHPDIEDFIETKVKEEEKIRALRDAGFDMDLGGDDIT
                     SVQYQNANNSVRVNDEFMTAVEKGGKFGLRARMTGEVIEEVDAKSLFRRMAEAAWACAD
                     PGIQYDDTINNWHTCPESGRITASNPCSEYMHLDNTSCNLASLNLMKFLKDDGKGHQSF
                     ETERFQKVVELVITAMDISICFADFPTQKIGENTRAFRQLGIGYANLGALLMATGHAYD
                     SDGGRSLAGGITSLMTGTAYRRSAELAAVVGTYDGYARNADAHNRVMKQHSDANGTAVR
                     MDDLDTPVWAAATEAWQDVVRLGERNGFRNSQASVLAPTGTIGLAMSCDTTGVEPDLAL
                     VKFKKLVGAGSMQIVNGTVPQALRRLGYQEEQIEAIVAHIAEHGNVIDAPGLAHEHYEV
                     FDCAMGERAISPMGHVRMMAAIQPWISGAISKTVNMPETATVEEVEEIYFEAWKLGVKA
                     LAIYRDNCKVGQPLSAKTKEKEKAEVTEKTETAIRETVEKVIEYRPVRKRLPKGRPGIT
                     TSFTVGGAEGYMTANSYPDDGLGEVFLKMSKQGSTLAGMMDAFSIAVSVGLQYGVPLET
                     YVSKFTNMRFEPAGMTDDPDVRMAQSIVDYIFRRLALDFLPFETRSALGIHSAEERQRH
                     LETGSYEQSLDDDEVDVEGLAQSAPRAQELKAVATPKAGTEAAEAAPKQAHTSAELVEM
                     QLGIQADAPLCFSCGTKMQRAGSCYICEGCGSTSGCS"
     gene            complement(8800..9351)
                     /gene="nrdR"
                     /locus_tag="D9753_RS09040"
                     /old_locus_tag="D9753_09040"
     CDS             complement(8800..9351)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0140110 - transcription regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="nrdR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139144.1"
                     /locus_tag="D9753_RS09040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09040"
                     /product="transcriptional regulator NrdR"
                     /protein_id="WP_121786537.1"
                     /transl_table=11
                     /translation="MHCPFCRHPDSRVVDSRTTDDGTSIRRRRQCPDCSRRFTTVETCS
                     LMVVKRSGVTEPFSRAKVINGVRKACQGRPVTEDALAQLGQRVEEAVRATGSAELTTHD
                     VGLAILGPLQELDLVAYLRFASVYRAFDSLDDFEAAIAELRDVTRGPAADDADAGAVDQ
                     EADCGPGGTTQVPAPAHAAD"
     misc_feature    9459..9473
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.81"
                     /tool="antismash"
     misc_feature    9490..9504
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 26.06"
                     /tool="antismash"
     misc_feature    9849..9864
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 23.09"
                     /tool="antismash"
     misc_feature    complement(9850..9863)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.93"
                     /tool="antismash"
     misc_feature    9850..9863
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.77"
                     /tool="antismash"
     gene            9924..10703
                     /gene="lexA"
                     /locus_tag="D9753_RS09045"
                     /old_locus_tag="D9753_09045"
     CDS             9924..10703
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019526308.1"
                     /locus_tag="D9753_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09045"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_121786538.1"
                     /transl_table=11
                     /translation="MTTTADSATITAQDRSQGRVEPVHVMNEVTNPEGHKRSLPGRPPG
                     IRADSSGLTDRQRRVIEVIRDSVQRRGYPPSMREIGQAVGLSSTSSVAHQLMALERKGF
                     LRRDPHRPRAYEVRGSDQAVTVQPTDTAGKPAASYVPLVGRIAAGGPILAEESVEDVFP
                     LPRQLVGDGELFVLKVVGDSMIEAAICDGDWVTVRRQPVAENGDIVAAMLDGEATVKRF
                     KREDGHVWLLPHNAAYEPIPGDDATILGKVVAVLRRV"
     gene            complement(10853..12869)
                     /locus_tag="D9753_RS09050"
                     /old_locus_tag="D9753_09050"
                     /pseudo=""
     CDS             complement(10853..12869)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004386 - helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139142.1"
                     /locus_tag="D9753_RS09050"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09050"
                     /product="ATP-dependent DNA helicase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTKPSLPELLHAAVAAVGGTERPGQVTMAEAVAEAIDDGSHLLVQ
                     AGTGTKVAGLPRARAGARRTGDRRDGHPRPPAPARGARPAAHGRRPAPAAAPPSGVRHA
                     QGPVELPVPAPAARGHAAGRGGGALRPVRGRRAHQQAGPGPPAAA"
     gene            complement(13118..13890)
                     /locus_tag="D9753_RS09060"
                     /old_locus_tag="D9753_09060"
                     /pseudo=""
     CDS             complement(13118..13890)
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1203: putative siderophore biosynthesis protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191053.1"
                     /locus_tag="D9753_RS09060"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09060"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPPTDAGAATSPAPAHQGCAGPGTDAAGLRGSRFRGFTVEDDDPD
                     SEDTLDLRLPADFIAFCAGTTVGTPDRLSAWGPVTTSAGTFRLLPVRIEHDLPLVHRWM
                     NDSAVASFWELAGPRNRTEEHLRTQLAGDGHSVPCLGVLNGTPMSYWEIYRADLDPLAR
                     HYPARPHDTGIHLLVGDAADRGRGLGSALLRAVADLILDRRVPHAHVS"
     gene            complement(14001..15953)
                     /locus_tag="D9753_RS09065"
                     /old_locus_tag="D9753_09065"
     CDS             complement(14001..15953)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675452.1"
                     /locus_tag="D9753_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09065"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_121786540.1"
                     /sec_met_domain="IucA_IucC (E-value: 2e-70, bitscore:
                     235.8, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNATPTPDGHSGAPDEPGGSGAPATPVPLTESVPPQKRRDADLTR
                     RTEPGADPLESPDPRTAAQAAAVENLLRCWVRETGLAAPTTGSLRIPLPASGTALTAPV
                     RYWSPTGWHRFGPPRLTGTPETAPPVDAVTLAALLVREPADDTSGAIRTVQPTAAGRGD
                     DDLVARVADSVRRTAAFIRHRRDHPADAPDLFLSAEQSLLLGHPLHPTPKSREGLTEAE
                     AQRYSPELHGSFPLHWLAVAPSVLATDSAWTERGRPVPAGHLVRRLAGTGLPLPDGYTA
                     LPLHPWQAREVRHRPSVAALLDSGLLRDLGPLGADWHPTSSVRTVHRSGAPAMLKLSLG
                     LRITNSRRENLRKELHRGVEVHRLLRTGLAEQWQAVHPGFDIVRDPAWLAVDGRDGMPV
                     PGLDAVIRHNPFAPADDAGCVAGLLSPRPSAEQTTNPSRGQVTWPMRSRLERLVARLAA
                     HTGRPVGAVATEWFLRYLEHVVRPVLWLDGEAGIALEAHQQNTLLLLDRDGWPAGGRYR
                     DNQGYYFRESRRAELEARLPGIGEHSDTFVPDEVTDERFTYYLAVNNVLGLIGAFGSQH
                     LADERLLLAAFRRFLTELATGPAALRSSLLARLLDSPVLRCKANLLTRLYGLDELVGPV
                     DTQSVYVTIANPLHS"
     gene            complement(16213..17814)
                     /locus_tag="D9753_RS09070"
                     /old_locus_tag="D9753_09070"
     CDS             complement(16213..17814)
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (44-378). E-value: 2.2e-89.
                     Score: 291.7. Matches aSDomain:
                     nrpspksdomains_D9753_RS09070_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997362.1"
                     /locus_tag="D9753_RS09070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09070"
                     /product="diaminobutyrate--2-oxoglutarate transaminase
                     family protein"
                     /protein_id="WP_240468091.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.1e-78, bitscore:
                     261.9, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVTESVAGDTPGRARAVHEGILRRQSARESSARTYARALPVVPV
                     RARGLTVEGADGRRYLDCLSGAGALALGHNHPVVLEAIRAVLDSGAPLSVLDLATPVKD
                     AFVTELFRTLPPGLADRARVQFCGPAGTDAVEAALTLARAATGRTGMLAFTGAYHGMTT
                     GALAVSGGAPDVQVARLPYPQDYRCPFGVGGPRGAELAARWTESLLDDPKSGVPLPAGM
                     IVEPVQGEGGVIPAPDDWLRRMRQLTADRSIPLIADEIQTGVGRTGSFWAVGHSGITPD
                     VMVLSKAIGGSLPLAVIVYRDDLDVWQPGAHAGTFRGNQLAMAAGTATLAYVRENGLAD
                     RAAALGARMLSRLQDLARDFPCVGDVRGRGLMIGLELVDPGAGGTAPGSETVPGCAIAP
                     GSGSAPGSAPGSGTVLGSASAPGERVAAPTGRAPTHAPHPVAAPAGLEPTRTPHPAAPR
                     LAAAVQRECLQRGLIVELGGRHAAVVRLLPPLTITDEQATAVLDRLADAVAAAARRHES
                     HGPHHQGRHGPAERAG"
     aSDomain        complement(16681..17682)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D9753_RS09070_Aminotran_3.1"
                     /evalue="2.20E-89"
                     /label="D9753_RS09070_Aminotran_3.1"
                     /locus_tag="D9753_RS09070"
                     /protein_end="378"
                     /protein_start="44"
                     /score="291.7"
                     /tool="antismash"
                     /translation="VRARGLTVEGADGRRYLDCLSGAGALALGHNHPVVLEAIRAVLDS
                     GAPLSVLDLATPVKDAFVTELFRTLPPGLADRARVQFCGPAGTDAVEAALTLARAATGR
                     TGMLAFTGAYHGMTTGALAVSGGAPDVQVARLPYPQDYRCPFGVGGPRGAELAARWTES
                     LLDDPKSGVPLPAGMIVEPVQGEGGVIPAPDDWLRRMRQLTADRSIPLIADEIQTGVGR
                     TGSFWAVGHSGITPDVMVLSKAIGGSLPLAVIVYRDDLDVWQPGAHAGTFRGNQLAMAA
                     GTATLAYVRENGLADRAAALGARMLSRLQDLARDFPCVGDVRGRGLMIGLELV"
     gene            complement(18055..19602)
                     /locus_tag="D9753_RS09075"
                     /old_locus_tag="D9753_09075"
     CDS             complement(18055..19602)
                     /NRPS_PKS="Domain: Beta_elim_lyase (198-392). E-value:
                     6.5e-07. Score: 20.8. Matches aSDomain:
                     nrpspksdomains_D9753_RS09075_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012503.5"
                     /locus_tag="D9753_RS09075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09075"
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="WP_240468092.1"
                     /transl_table=11
                     /translation="MNHSTPATTGTGHRVALAGTPDGLEQLGTLVTAALDAVSAAAAER
                     TGPLPAGGPDAAIAAVRDLVRDGGFLTDAPGPHRVEELFEAYAGWAADLTHPAAVSRMQ
                     CAPTPAAAAAELLAAVLNQSLHSWESGPFALELERRLIAEMADWVGYGETASGTLTPGG
                     SISNLMGLLLSRDHVLGGLTGDDISHTGLAGRAIRPRILCSTAAHFSVARAAGFLGLGR
                     DAVVRVPADERGRMIPEEARRLLDGFAPDEVPIALVATAGTTDHGSFDPLPELAALAAE
                     RRIWFHVDAAYGIGALFSDTLRPLFDGLAEADSIAFDLHKFGWTPASSSILLVRDRARM
                     SPLGQQAVYLNPPDDEAEGYTALLGTSLQTTRRADAFKIAASLLALGREGMGEWVDACH
                     SQARYAAARITRDPDLELLAEPILSTVVFRCRAGAAIEDESTWNAAVRRHLMAEGKALL
                     ARTKVRRQDGQAQVHLKLVFLNPATTTQDIDALLDDVVAAAAEVRQSPKARTPQTAH"
     aSDomain        complement(18427..19008)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D9753_RS09075_Beta_elim_lyase.1"
                     /evalue="6.50E-07"
                     /label="D9753_RS09075_Beta_elim_lyase.1"
                     /locus_tag="D9753_RS09075"
                     /protein_end="392"
                     /protein_start="198"
                     /score="20.8"
                     /tool="antismash"
                     /translation="PRILCSTAAHFSVARAAGFLGLGRDAVVRVPADERGRMIPEEARR
                     LLDGFAPDEVPIALVATAGTTDHGSFDPLPELAALAAERRIWFHVDAAYGIGALFSDTL
                     RPLFDGLAEADSIAFDLHKFGWTPASSSILLVRDRARMSPLGQQAVYLNPPDDEAEGYT
                     ALLGTSLQTTRRADAFKIAASLLALGREGMG"
     gene            complement(19648..20568)
                     /locus_tag="D9753_RS09080"
                     /old_locus_tag="D9753_09080"
     CDS             complement(19648..20568)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013088.5"
                     /locus_tag="D9753_RS09080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09080"
                     /product="DMT family transporter"
                     /protein_id="WP_121786543.1"
                     /transl_table=11
                     /translation="MSVEAGVGAQPAEAAPPGTPGAADPGARGLGLVPAPVLMLIGMVS
                     TQLGAAFAKQMFGTVGPAVMTVLRLGFAAAALLLWWRPSFRLERRTALAVAGLGITIAG
                     MNMCFYLAMARLPVGVALTIGMSGPLMVAALSSRRGRDRMWTLLAGAGIALLGWQGGAT
                     GLAGLLISAACAVFWGAYVPLSARVGAQLPGGGGLALAMLFGTLCALPFGLAEGGSVLG
                     HPWALAFGFGVAMLSSLVPYTCEMETLRRVPALVFGVLLSLEPAIGALVALIVLGETLS
                     AGQVLGLASVVVASIGVIRGTRATT"
     gene            complement(20629..21591)
                     /locus_tag="D9753_RS09085"
                     /old_locus_tag="D9753_09085"
     CDS             complement(20629..21591)
                     /NRPS_PKS="Domain: PKS_ER (18-318). E-value: 1.5e-43.
                     Score: 141.1. Matches aSDomain:
                     nrpspksdomains_D9753_RS09085_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378326.1"
                     /locus_tag="D9753_RS09085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09085"
                     /product="quinone oxidoreductase"
                     /protein_id="WP_121786544.1"
                     /sec_met_domain="ADH_N (E-value: 3.1e-09, bitscore: 35.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.3e-24, bitscore:
                     85.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAIQVTRAGGSAALTPVELPEPAPAAGEAVVRNAVIGLNFIDVY
                     FRDGTYPAPCPFVPGQEAAGTVTAVGEGVEGIAVGDRVAYATQLGAYAESTAVPAAKLV
                     PVPENIHLRDAAAVLLQGLAAHYLTHTTHPVTAGETVVVLAAAGGLGRLLVQLAAHRGA
                     TVIAVASTEDKQRLALDAGARHALPYDGFAERVRELTGGEGAHVVYDSVGADTFDQSLA
                     APRRRGHLVVCGLSSGPVGAIDVERLRTAGSLTLTRPSLADHVPDTAALRAAAAAVFTH
                     VADGVVRPRVQTELPLSEAARAHDLLEGRGTTGKVLLRP"
     aSDomain        complement(20638..21537)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D9753_RS09085_PKS_ER.1"
                     /evalue="1.50E-43"
                     /label="D9753_RS09085_PKS_ER.1"
                     /locus_tag="D9753_RS09085"
                     /protein_end="318"
                     /protein_start="18"
                     /score="141.1"
                     /tool="antismash"
                     /translation="ELPEPAPAAGEAVVRNAVIGLNFIDVYFRDGTYPAPCPFVPGQEA
                     AGTVTAVGEGVEGIAVGDRVAYATQLGAYAESTAVPAAKLVPVPENIHLRDAAAVLLQG
                     LAAHYLTHTTHPVTAGETVVVLAAAGGLGRLLVQLAAHRGATVIAVASTEDKQRLALDA
                     GARHALPYDGFAERVRELTGGEGAHVVYDSVGADTFDQSLAAPRRRGHLVVCGLSSGPV
                     GAIDVERLRTAGSLTLTRPSLADHVPDTAALRAAAAAVFTHVADGVVRPRVQTELPLSE
                     AARAHDLLEGRGTTGKVLL"
     CDS_motif       complement(20755..20871)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_D9753_RS09085_0003"
                     /evalue="1.50E-01"
                     /label="C2_DCL_024-062"
                     /locus_tag="D9753_RS09085"
                     /protein_end="279"
                     /protein_start="240"
                     /score="4.4"
                     /tool="antismash"
                     /translation="GAIDVERLRTAGSLTLTRPSLADHVPDTAALRAAAAAVF"
     CDS_motif       complement(21118..21180)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_D9753_RS09085_0002"
                     /evalue="3.20E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="D9753_RS09085"
                     /protein_end="158"
                     /protein_start="137"
                     /score="10.3"
                     /tool="antismash"
                     /translation="GETVVVLAAAGGLGRLLVQLA"
     CDS_motif       complement(21379..21414)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_D9753_RS09085_0001"
                     /evalue="3.10E-04"
                     /label="PKSI-ER_m2"
                     /locus_tag="D9753_RS09085"
                     /protein_end="71"
                     /protein_start="59"
                     /score="13.6"
                     /tool="antismash"
                     /translation="GQEAAGTVTAVG"
     gene            complement(21599..23056)
                     /locus_tag="D9753_RS09090"
                     /old_locus_tag="D9753_09090"
     CDS             complement(21599..23056)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378322.1"
                     /locus_tag="D9753_RS09090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09090"
                     /product="methylaspartate mutase"
                     /protein_id="WP_121786545.1"
                     /transl_table=11
                     /translation="MTGTHKPLALLGGTAGKGPAGDTAADLPTAAESAAYIAGLGKPTA
                     AEVLERCRAAGRVAIQPRCGVGGHAEMTDLLRALEAEAHPDILTLTIDSHTRLKRFEEA
                     LRSLNLRPTDLNGYPLVAHGWRRGRELNESVAAPLEIRHGSPDARRLFDVSVASGITSF
                     EGGGISYNLPYSKAVPLTESLGAWQDVDRRCGELAELGVVIDRELFGTLTAVLVPPSVS
                     LAISVVEAVLAARAGVRCISVAYPQGGHLAQDIAALRCIPVLAERYLPTGIDVHAVLHE
                     FMGVFPRQRGNAEDLILYGALVARLGGASKLITKTYQEAYGIPDTRANVEGLRLADRAN
                     SPLLDFLRVDEARVAEEMEWILAEVGDLVDPLIERADLIEAAAEAFERGALDIPFSASR
                     YARSDVIPRRDAEGAIRYLSAGSLPFSAANRRRNEELLAARPGTEVALGSLMAGLTGDI
                     NYFRTVFDETDGTGSPGTTGAGIPVSK"
     gene            complement(23053..23508)
                     /locus_tag="D9753_RS09095"
                     /old_locus_tag="D9753_09095"
     CDS             complement(23053..23508)
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378320.1"
                     /locus_tag="D9753_RS09095"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog.; Presence of a B(12)
                     (cobalamin)-binding domain implies dependence on cobalamin
                     itself, in one of its several forms, or in some unusual
                     lineages, dependence on a cobalamin-like analog.; Presence
                     of a B(12) (cobalamin)-binding domain implies dependence on
                     cobalamin itself, in one of its several forms, or in some
                     unusual lineages, dependence on a cobalamin-like analog.;
                     Presence of a B(12) (cobalamin)-binding domain implies
                     dependence on cobalamin itself, in one of its several
                     forms, or in some unusual lineages, dependence on a
                     cobalamin-like analog.; Presence of a B(12)
                     (cobalamin)-binding domain implies dependence on cobalamin
                     itself, in one of its several forms, or in some unusual
                     lineages, dependence on a cobalamin-like analog; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="D9753_09095"
                     /product="cobalamin-dependent protein"
                     /protein_id="WP_121786546.1"
                     /transl_table=11
                     /translation="MQSKQATPTRTVILGVAASDSHAVANHLIAYALRGAGFDVVNLGT
                     CTPVEEFAQACAAHPDAEAVIIGSLNGHIHEDLRGLAETKRSGKINCPVVVGGNLSVGS
                     HKDGSAYERLHALGVDHILSDPDGLPALLDGLRATRDGATASLRTAS"
     gene            complement(23540..24721)
                     /locus_tag="D9753_RS09100"
                     /old_locus_tag="D9753_09100"
     CDS             complement(23540..24721)
                     /EC_number="1.14.19.-"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378330.1"
                     /locus_tag="D9753_RS09100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09100"
                     /product="fatty acid desaturase"
                     /protein_id="WP_205614096.1"
                     /transl_table=11
                     /translation="MSPPGPQDPRETLTRLPKALQFPLTLFTGKALPGQAAPGWTPTLH
                     LATALSSVVAGVLVGTLGYALGGGWPLLLIPGWAITLHGMRNLRMMTYHQCSHRNMYRR
                     RKLDRFIGHGVSSLLIIQNFQRYSREHVKDHHAAGHMTLKDPTVQAFLVSLELHPGMTR
                     RRMWRRVLGKLVSPRFHFAFAVSRARSFWSESARSEKVCALVLYGGAVAATVLTGTWPA
                     LLLIWFVPLVPLFQVSNTLRLCVKHTFPEPGVEIRHGREYFSSLTNAIFIGDPAPSAGL
                     PAGRRLAAWARWTLRLVFVHAPCRYLVLTGDTVVHDYHHRYPAAPDWANYIFARQQDID
                     AGHQGWPPYHEVWGLVPAISHVFDSLSRADAQEYDINRLKAVSKRELFAAFDD"
     gene            complement(24829..25128)
                     /locus_tag="D9753_RS09105"
                     /old_locus_tag="D9753_09105"
     CDS             complement(24829..25128)
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014677205.1"
                     /locus_tag="D9753_RS09105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09105"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_121786547.1"
                     /transl_table=11
                     /translation="MDLKKLTLMPYGLEVQLPAGSPLTDLERGTSQRVIPFGCQQGACG
                     ACVIEVLDGFDALGEMDPEEADFLEDLGQTGGNYRLACQCRLMSAATVRVADAL"
     cand_cluster    24924..35865
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    24924..35865
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[29923:30865](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      29924..30865
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     gene            complement(25281..26297)
                     /locus_tag="D9753_RS09110"
                     /old_locus_tag="D9753_09110"
     CDS             complement(25281..26297)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009720176.1"
                     /locus_tag="D9753_RS09110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09110"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_121786548.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.9e-24, bitscore:
                     85.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPASIDSDVDLAIVGAGPSGLHAAYYAGFRGLTTAVLDTLPHAGG
                     QVAAMYPEKPLYDIPAHPAIKGRDLVENLLRQAAPFEPRYLLGQTATTLARTGTGWTLG
                     TDRGACVRAGAVLITAGLGAAVPRRLPAAADHEGRGVTHHVPRLDEHRDRDVVIAGGGD
                     SAVDWALALAPVARSVTLVHRRAAFRAHEYSVRQLYAAPVRIITDALITRCLGGRRLEA
                     VEVRAGDDLLTLPASALITALGFSTQLGPIADWDVELEFRQIKVDATMRTNLPGVYAAG
                     DVCTHPGRVPLISVGFAEAATAVNHAAVALRPGERLAPGHSSDAVPPPEPPLPAAVA"
     misc_feature    complement(26610..26630)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 19.72"
                     /tool="antismash"
     gene            complement(26690..27256)
                     /locus_tag="D9753_RS09115"
                     /old_locus_tag="D9753_09115"
     CDS             complement(26690..27256)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF044515.2"
                     /locus_tag="D9753_RS09115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09115"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_121786549.1"
                     /transl_table=11
                     /translation="MASQERSARTRQRLVFAAATAIAESGYEGATLARICKAAQVSIGA
                     LTFHFSSKRDLADAVRADARTLTHDRMRQAVDAASAPGAALPCLVRLTVQLAHLLETEV
                     VVRSAARLARDCPDDDAWVSTWLPVVRRLLAQAQCSGELRAGVDPQVMTVLVNHLVFGA
                     PPAPGAASQLERVWEVVLRGAASLR"
     gene            complement(27438..28190)
                     /locus_tag="D9753_RS09120"
                     /old_locus_tag="D9753_09120"
     CDS             complement(27438..28190)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (5-173). E-value: 4.8e-15. Score:
                     47.9. Matches aSDomain:
                     nrpspksdomains_D9753_RS09120_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891482.1"
                     /locus_tag="D9753_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09120"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_121786550.1"
                     /sec_met_domain="adh_short (E-value: 1e-36, bitscore:
                     125.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 5.1e-34, bitscore:
                     117.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKGKVAMITGASSGIGAAAARLFAEEGAAVVLMARRGDRLEQLV
                     AEIRAAGGRALAVEGDVCSSDDVERAVTAAVDTFGGLDAAFNNAGYATVGTPLLEMDDE
                     DYARTMDVNVRGVWNCLRRQLPVMLASGGGAVVNTSSVAGVLASSASAAYVAAKHAVIG
                     LSRAAAREYGDRGIRVNALVVGSTRTEMMDQVIAGSREVEERFEARTLRRRMASPDEIA
                     QAAVWLCSDRAAFVTGAAVPVDGGRTAV"
     aSDomain        complement(27672..28175)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D9753_RS09120_PKS_KR.1"
                     /evalue="4.80E-15"
                     /label="D9753_RS09120_PKS_KR.1"
                     /locus_tag="D9753_RS09120"
                     /protein_end="173"
                     /protein_start="5"
                     /score="47.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAMITGASSGIGAAAARLFAEEGAAVVLMARRGDRLEQLVAEIRA
                     AGGRALAVEGDVCSSDDVERAVTAAVDTFGGLDAAFNNAGYATVGTPLLEMDDEDYART
                     MDVNVRGVWNCLRRQLPVMLASGGGAVVNTSSVAGVLASSASAAYVAAKHAVIGLSRAA
                     AREYG"
     CDS_motif       complement(27720..27782)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_D9753_RS09120_0002"
                     /evalue="1.50E-01"
                     /label="PKSI-KR_m4"
                     /locus_tag="D9753_RS09120"
                     /protein_end="157"
                     /protein_start="136"
                     /score="4.6"
                     /tool="antismash"
                     /translation="VNTSSVAGVLASSASAAYVAA"
     CDS_motif       complement(28080..28166)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_D9753_RS09120_0001"
                     /evalue="5.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="D9753_RS09120"
                     /protein_end="37"
                     /protein_start="8"
                     /score="15.8"
                     /tool="antismash"
                     /translation="ITGASSGIGAAAARLFAEEGAAVVLMARR"
     gene            complement(28192..28890)
                     /locus_tag="D9753_RS09125"
                     /old_locus_tag="D9753_09125"
     CDS             complement(28192..28890)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010041695.1"
                     /locus_tag="D9753_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09125"
                     /product="HAD family hydrolase"
                     /protein_id="WP_121786551.1"
                     /transl_table=11
                     /translation="MVHTLNRLRLAAVNIDGVLLNDTFSPVIHRFLVDRGCVYTAELER
                     SIFSQPRAVAGRLLAEAIGGSVTPQAALELYFRDRAEYLETHPARLDEGAVELLRRLRA
                     AGLRTVCYGGLDKEHFDTFLGPYADLFDDPGYICTDTFRPGVHEIVTEYFGLKYDEALF
                     IDDVANVGRAARELGVPFIGHPSDFRHSFQPQLMREAGVRHIVDSLDAVDEELLRTLDE
                     EAALGTVWRD"
     misc_feature    28867..28884
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            complement(29048..29716)
                     /locus_tag="D9753_RS09130"
                     /old_locus_tag="D9753_09130"
     CDS             complement(29048..29716)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014628787.1"
                     /locus_tag="D9753_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09130"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_121786552.1"
                     /transl_table=11
                     /translation="MGQPRQERAIQTRGALILAAAEVFDEYGFAGASISRILKRAGVTA
                     GALYFHFESKEALAKAVMNAQSDTILPFLESQGLQRLVDITLVWARRLQTDPLLRAGVR
                     LTGEQTTFGLRDSSPYQAWSQIMEECLLAARERGELQAGVEPSELAELIVEACTGMQMY
                     AAAETCRADLSDRVVRMWRLLLPGIAVPSVVARTAVDPARALAAEEATAPVGAPGDGTG
                     "
     misc_feature    29841..29854
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.25"
                     /tool="antismash"
     gene            29924..30865
                     /locus_tag="D9753_RS09135"
                     /old_locus_tag="D9753_09135"
     CDS             29924..30865
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010644108.1"
                     /locus_tag="D9753_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09135"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_121786553.1"
                     /sec_met_domain="AfsA (E-value: 2.5e-21, bitscore: 74.2,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAITSREGRSAPGSTSVIDPVPRELVHKLAESEVLLRGCRTVAP
                     DTFLITARWPVDHSFYGPVHGLFDPLLAAESIRQAVPLLSHAAYDAPFGHRQSWDHYRQ
                     TLFPAALTSGTTAAETELRISCTDVVRRASRLASLTMRVDMVRGGLPLGTAELAFHNHP
                     PAIYQRLRGPYADLERSTAQAVAAPPPMAPGEVARPRPADVVLSATEDPGRSRLRVDLS
                     HPVLFDHPVDHVPGMLLLEAARQAAHRVAHPEPMVVTGLEADFKRFVELDTPCWIETAR
                     EPSGAAGQRVRVTAVQRDETLFTSVVTLTPAW"
     gene            31056..32277
                     /locus_tag="D9753_RS09140"
                     /old_locus_tag="D9753_09140"
                     /pseudo=""
     CDS             31056..32277
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973224.1"
                     /locus_tag="D9753_RS09140"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09140"
                     /product="trypsin-like serine peptidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRSIRPSFTVLRGRGPHRTARALTAVALASALAMTATACGGDNAE
                     GKPTAGATAGGSGDGKLRIPDDLRQRLKEHGIDIDKWKKGAWKNWNKQDWLREADDFVN
                     PMIKGLWNPDRMRDADDPDKGVDDNDISGDQGVTDPAPQPVRARTVVPPYHSNAATSGK
                     LLFDAPEGTMVCSATVVTDPAHPGKSNLVWTAGHCVHAGKKGGWYRNLAFVPSYNNQGR
                     SAAELENTGRSEVAPYGVWWADAAKTSQQWISEGGATGGNGASYDFAVIHVTPERGSGG
                     ESLEETVGGALPVDFDAPAVPKVQSLTASGYPAAAPYDGQLLYQCQDHPGRLSMDRSDP
                     TMYRIGCTMTGGSSGGGWVETGADGKPALVSNTSIGPGEFGLAGRPPAG"
     gene            complement(32463..33950)
                     /gene="hflX"
                     /locus_tag="D9753_RS09145"
                     /old_locus_tag="D9753_09145"
     CDS             complement(32463..33950)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="hflX"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020139137.1"
                     /locus_tag="D9753_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09145"
                     /product="GTPase HflX"
                     /protein_id="WP_121786554.1"
                     /transl_table=11
                     /translation="MTSSSSPSQDTKRLAHAYPEGLRADALMEEDVAWSFESDGERDGD
                     QLDRSERAALRRVAGLSTELEDVTEVEYRQLRLERVVLVGVWTTGTAQDADNSLAELAA
                     LAETAGAIVLDGVIQRRDKPDAATYIGSGKALELRDVVLETGADTVICDGELSPGQLIQ
                     LEDVVKVKVIDRTALILDIFAQHAKSREGKAQVALAQMQYMLPRLRGWGQSLSRQMGGG
                     RGGLATRGPGETKIETDRRRIREKMAKMRREIADMKTGREVKRQERRRNKVPSVAIAGY
                     TNAGKSSLLNRLTGAGVLVENALFATLDPTVRRAETPSGRLYTLADTVGFVRHLPHHLV
                     EAFRSTMEEVGDSDLILHVVDGSHPNPEEQLAAVREVIRDVGATGVPEIVVINKADAAD
                     PLVLQRLLRVEKRSLAVSARTGQGIDKLLALIDDELPRPSVEVEAVVPYTHGKLVARAH
                     TEGEVISEEHTAEGTLLKLRVHEELAADLAPYTVTTV"
     misc_feature    33954..33968
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            complement(34112..35614)
                     /locus_tag="D9753_RS09150"
                     /old_locus_tag="D9753_09150"
     CDS             complement(34112..35614)
                     /EC_number="3.4.11.-"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125067.1"
                     /locus_tag="D9753_RS09150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_09150"
                     /product="M1 family metallopeptidase"
                     /protein_id="WP_121786555.1"
                     /transl_table=11
                     /translation="MLLTPRHRSRPRISRHRKAALLACAVSVCLVAAAAPPEPLGVGDR
                     LYPYLGNPGYDVASYDISLTYAGTNDKPLQAVTTIDARTTADLDRVNLDFAHGTVRSVE
                     VDGRPARFTSAGEDLVVTPRTPLTEGSRTRITVRHTSDPAPAKDQDGGWVRTVDGLAMA
                     NQADAAHLVFPGNDHPSDKAMFTFRITAPDGCTAVANGLPTGAYRVGRTTTWTYRTLHP
                     MATELAQVSIGRSAVVHRAGPHGLPLRDVVPAADHKALEPWLARTPDQIAWMESKVGRY
                     PFETYGVLMAQAATGFELETQTLSLFEKDLFTKPAYPEWYIESVMVHELSHQWFGDSVT
                     PRTWSDVWLNEGHATWYEELYAEETAHRPMKDRMKAAYGAADRWRESGGPPARPKPPAP
                     GQKIGIFRPSVYDGAALALYALRQEIGRPAFERLERLWVQEHRDATATTADFVRLASAV
                     AGRDLRGFLDAWLYGEKTPPMPGHPDWRPTAKTGPAEPRARR"
ORIGIN
        1 tccaccacgc tccccacgat caccccctcg aagcgctccg cttgcagttg atcgcattcg
       61 tgaatgaccg aacggattgc gaccccgggg cgcgagaaca tgatctgccg tacctgccga
      121 cacagcgtga gcaggtcctc gcggatgctt ccgaggtcgg gggcctcctc cagccggggc
      181 agcccggcca ccagcgcgtc ggcgaccaga tcctccttgg acggccagcg gcggtagacc
      241 gcggccttgc ccgtctgggc ctcggccgcg actccctcca tggtcagccc cttccagccg
      301 accgtgctca gctgctccag tgcggcgtcg aggatcgcgc gctccagcac cgcgccgcgc
      361 cgacgagggg aagccgtgcg atcgggcgcg gccgtccagc gcgaggtagc catctgtatt
      421 tctccagcat gcaaagggaa gcggggattc cgggagcggc gggtgcgcgt cacggcaatg
      481 ggggacgcga gacgcggcac gccattaagt gaacgcttgc gttcactgtt ggggactcac
      541 taccgtgggc gcgacagtga acgcgagcgt tcactaacgc cttgatgggg gacccatagt
      601 gacgacctct cagttgctcc aggacgatcg gaaaccgggc acggcccgcc gggaggggca
      661 tcccggcatc gcgctcaccg tcatcgcggc ctgccaactc atggtggtgc tcgacgcgac
      721 gattgtgaac atcgcactcc cgcacattca agacgctctc aagttcagca ccaccgacct
      781 cacttgggtg gtcagcgcct acacgctcac cttcggcggc ctgcttctgc tcggtgcccg
      841 ggccggtgac atcctcggcc ggcgccgggt gttcatggcc ggcatcctgc tgttcacctt
      901 cgcctctctg ctgggcggcc tggcccagga gccctggcag ttgctggccg cgcgggcctt
      961 gcagggcgtg ggtggcgcga tcgcgtcgcc cacgtcgctc gcgctgatca cgacgacctt
     1021 ccccgagggg ccggaacgca accgggcctt cggcgtgttc gcggccgtgt ccgccggcgg
     1081 tggtgccatc ggcctgctcg cgggcggcat gctcaccgac tggctcgact ggcggtgggt
     1141 gctgttcgtc aacgtgccca tcggcgtgct gatcgcgtcg ctcgcgccgc tgtacatcaa
     1201 cgaatcccgg cgtcacccgg ggcgcttcga cctcaccggt gcgctgacct ccacgacggg
     1261 catggccacg ctggtgtacg ggttcatccg tgccgcggag gagggctggc gggacgctct
     1321 caccctcggt tcgttcgccg cgtccgccgt cctgctgttc gccttcgtct tcatcgagat
     1381 gcgggcgaag gagccgatca ctccgctcag gatgttcacc gaccggaacc gctggggcac
     1441 gtacgtgatc atgctcagcc tggccgcggc gatgttcggc atgttcttct acatcgtgct
     1501 gttcgtgcag aacgtgctcg gctacagcgc catcaaagcc ggtgtcgcct tccttcccgt
     1561 gaccgtggcg atcgcgatcg gcgcgggcct gtcccagcgc ttcctgccgg ccttcggtcc
     1621 caagccgttc atgatgaccg gttcggcgtt cgtggtggtc ggactgacct ggcagacgct
     1681 catccgtccc gacagcagct acgtcggcgg agtgctgggc ccgctgctgg tgttcggctt
     1741 cggcatgggc ctgaacttcg tgacggccac cgtcaccgcc gtgtccggcg tcgcccagca
     1801 cgaggcgggc gcggcgtccg ggctgctcaa cgccatgcag caggtcggcg gctcgctcgg
     1861 cctgtccatt ctgacgaccg tcttcggttc ggccggcaag gacgaggcga agaagcagct
     1921 gccgaagttc ctcgccgacg gctcgccgga acagaaagcg cagttcgcca agacgcatca
     1981 gttgcccgcg ccctggggac acgaggtgct cgcccatggc atctcgacgg ccttcgtccc
     2041 ggccgccgcg atggccgtcc tcgccttcct caccgcctgg ctggtgatca gggtccgcaa
     2101 gagcgatctc gactccctcg cgggcgtggc gggcccgggc atcggctgat ccgggccgcg
     2161 cggcacggag ccgcggccga ccggaccgcc gcccgggcgc gggcggcgcg gaccacggac
     2221 cggtcggccg cagcaggggc gccggaggca ccggcaccag ggacaccagc gcccacgcca
     2281 ggaagaccag cgacgcagcc ggccccggca ggacatacgc catctcgcgc ccctccctcc
     2341 ctcgtgtcgg ttctcgccgt cgccgctccc tccgccctcg cgtcgggaga cgcggtgcgc
     2401 ggcggatacg ggaagaacga gcgtcgatca cggagagttc ccggcggaca cggagcgttc
     2461 ttggggcggc ccgggccgac gtggggggac tgtcagagac ccgcggacac ccactccggc
     2521 agcgcctcgg tccgctgcac ccactcggcc ggcggcgccc cggccttgcc tgcggccagc
     2581 acgccgccca cgatcgcgca ggtggtgtcc atgtccccgc ccacctgggc ggtcgtccag
     2641 aacgccgtct cgtagtcacc gagggcccgc gcggcggacc acagggcgaa ggggacggtg
     2701 tcgtgcgcgg tcgtacggcg tccgctgccc agcacggccg cgacggtggc cgggtcgccg
     2761 tagtcgagca tgtcgcgagc gcggcggagg ccctggccga ccgcgctctt cggcacgagc
     2821 gcgatgacgc cgtcgaggag tgcctcgccg ctgggcgggc cgtcgggcga gccggccagg
     2881 gccgctgccg cggccaccgc catggccccg accacggcct cccggtgctg gtgcgtgggg
     2941 taggccgaga tctccgcctg gtgggtcgcc tgctcgggat catccgcgta ccaggcaccc
     3001 aggggggcga tccgcatggc cgcgccgttg ccccaggacc cctgcccgtt gaagaggccg
     3061 gcggccagct cccgccagtc cccgccctcc cggaccagac gcagcaggcg gttgaccgcg
     3121 ggaccgtagc cccggtcgaa gtcgtggtgc tcggcgaagg agcgggcgag cgcgtcctgg
     3181 tcgatgcgct ggtgtgcggc gaggacggcc accacggaac aggccatctc cgtgtcgtcc
     3241 gtccactgcc aggggcccgg gggcagttcc cggcgcttca gcagggggta gttcaccgga
     3301 acgaagaact gggagcccag cgcgtctccg acggccagtc cacgcaggct cgccgaggcg
     3361 cgctcgaagc gctcgaggga agaggagtca gcggtcatcg ctctgccact ctatccgctg
     3421 acccagtacg ggaccggctc ccgccagcgt tcgaaggacc ggtcgagtgc gtacctgccg
     3481 tcctccccga gaacgagcat ccgcatctcg gcgttccccg gattggccag cgactcgaat
     3541 tcggcgaccg tccagtggaa ccaccgcatg cagaacagcc gcatcgccag tccgtgggtc
     3601 accaggagca cgttcggagg atggtcgggg gcctcgaagc tgcggaacag gctctccagg
     3661 aagcctccga cccggtcgta cacgtcggcg ccggactctc cctgcgggaa ccggaagaag
     3721 aagtggccgt aggcgtcgcg ataggccttc tggaggcgca cgtcgtcgcg gtcctgccag
     3781 tttccccagt cctgctcccg gagcctgggc tcctcccgga cgcgtatgag gtcggagtcg
     3841 aggtggaagg cgcggagcgt ctcgtgggta cggcggtacg gggagacgta cacgctcacg
     3901 cgttccctgc cgaagagctg ccggagccgc tctccggtct cctcggcctg ccgccggccg
     3961 cgctcggtca gcgcgagggc gtggtcgggt tcgcgttcgt acacggagtc gtcgatgttg
     4021 ccggtcgact cgccgtgccg gacaaggacg atgcgccgtg gtcgtgccat gccgaaaccc
     4081 tagatcgaac ggcggaaggt cgagcactcg tacgggctcc atacggcgta ggtcacacga
     4141 tttccgcgcc gcgcaccctt ccgtgacctc gacgcggcga tcccgcgcag tgcatccgat
     4201 tctccaaccg accggcgtgg cctcagaccg tccaagacgg ctccagttcc acgatgtcgc
     4261 cggagagcgc cgcgacgtcc gcctcggtct gggcgcgcag ggccaggcgt tcgatgcgtt
     4321 cggtgcggta cttgccgtgc tcggccgccg atcgccacat cgagaggatc aggaactcct
     4381 gttcgggtgc ctcggcgaac atgccgcgga tcatgccggg cgacccggcc atggccgggt
     4441 tccagacctt ctcctgcatg agcgtgaagt gctccacgcg ctcctcgtgg atccggcaca
     4501 gcgccacccg gacgagatcg gcgtcggtga agcgcggctc gaagcccgtc ttcacgtcga
     4561 agcggtactc gaacagcctg acctgggcgt ccttgaaagt gccggactgg gcggcggcca
     4621 ggcggtcatg ggaacgggcc atgaaggagt cgtagaaggc gcggctctcc cagaaggcga
     4681 agacgtgcgc cacccccggc cgctgccggc tccagccccc gccctgaccc cggaaacccg
     4741 gctcccccgg aagccccgcc catttccgct gcccgcgctc gaaaccgcgg cggtcgacca
     4801 cggtgcagcg aatccacttg accagcaccg cgccatcgta aggccaccgg gcgtggcgcc
     4861 ggtcacgctc tgctggacaa cgcccgggcg tgcgccccca cgcacgtggc acgatggaca
     4921 aaaagcgtcc gactcaacgg agttgggggc gagtgagcca caggggggaa ggggcagcct
     4981 ggtgaccggc ttcagcaagg gactccgcaa ggtcgagatc gcgctcaagt gggatcccag
     5041 tccggcggga cggccgccga ccgatctcga catcatcgcc gcgacgttcg tgtcggccga
     5101 cgcttacggg acgccggcct atctggtgca cttcgacagc cgttcgcccg acggcacgat
     5161 cttcctcaac cgcgacagca cggacggcag gggcttcggc tgggacgagg tcatgatgct
     5221 cgagctggaa cggctcgaca gccggtacgc gcgcgtggtg gtgggtgtcg tcatccagca
     5281 ggggcccggg tacaagacgt tcgccgacgt actgaacccg gccgtgcgcg tccgggaggg
     5341 ttacacggtc ctcgccgagg acgacttcgc atcggtcctc ggtgcgacgg ccgcgacgat
     5401 cgccgagttc gtgcgcgacg actccggcga gtggaccctg cgtcccggcg tgcacggctt
     5461 cgacgaggac ccggcgacct tcacccaggt catgggcagg gcacgccggc cctgacgccg
     5521 tggcaggtaa ggggcgtcgg ccaaggcggg cgccccttac ctgtggcggc cccgacgccg
     5581 acccgggggt gaccggcgag ggtgagtccc cctcggcagc cacagggctg tccggtcgcc
     5641 gggtgtgcgc ggaaaaggcg ccggcttgtg gccggcgccc cttccatttc accggggact
     5701 actcgtcagg cccccttccg gctgctggtc agctgcagcc gctggtcgag ccgcagccct
     5761 cgcagatgta gcaggaaccg gcccgctgca tcttcgtacc gcaggagaag cacagcgggg
     5821 cgtcggcctg gatgcctagc tgcatctcga ccagctcggc gctggtgtgg gcctgcttcg
     5881 gggcggcctc ggcagcctcg gtcccggcct tcggcgtggc gaccgccttc agctcctggg
     5941 cgcggggcgc cgactgggcc agaccttcga cgtcgacctc gtcgtcgtcg agggactgct
     6001 cgtacgaacc ggtctccagg tggcgctggc gctcctcggc ggagtggatg ccgagcgcgg
     6061 agcgcgtctc gaagggcagg aagtccagtg ccaggcggcg gaagatgtag tcgacgatcg
     6121 actgcgccat ccgcacgtcg gggtcgtccg tcatgccggc cggctcgaag cgcatgttgg
     6181 tgaacttcga gacgtacgtc tccagcggca cgccgtactg gagaccgacg gagacggcga
     6241 tggagaaggc gtccatcatg cccgcgaggg tggagccctg cttggacatc ttcaggaaga
     6301 cctcgccgag accgtcgtcc gggtaggagt tggccgtcat gtagccctcg gcgccaccga
     6361 ccgtgaagga ggtggtgatc cccgggcggc ccttggggag gcgcttgcgg accgggcggt
     6421 actcgatgac cttctcgacc gtctcgcgga tggccgtctc ggtcttctcc gtgacctcgg
     6481 ccttctcctt ctccttggtc ttcgcggaga ggggctggcc gaccttgcag ttgtcgcggt
     6541 agatcgcgag tgccttgacg cccagcttcc aggcctcgaa gtagatctcc tcgacctctt
     6601 cgacggtcgc cgtctccggc atgttgaccg tcttggagat ggctccggag atccacggct
     6661 ggatcgcggc catcatgcgg acgtggccca tcggggagat ggcgcgctcg cccatggcgc
     6721 agtcgaacac ctcgtagtgc tcgtgcgcga ggccgggggc gtcgatcacg ttgccgtgct
     6781 cggcgatgtg ggcgacgatc gcctcgatct gctcctcctg gtaacccagg cggcgcaggg
     6841 cctgcggaac ggtgccgttg acgatctgca tcgagccggc gccgacgagc ttcttgaact
     6901 tgaccagggc gaggtcgggc tcgacgccgg tggtgtcgca ggacatcgcg agaccgatgg
     6961 tgccggtcgg ggcgaggacg gacgcctggg agttgcggaa accgttcctc tcgccgaggc
     7021 ggaccacgtc ctgccaagcc tccgtggcgg cggcccacac cggggtgtcc aggtcgtcca
     7081 tgcggacggc cgtgccgttg gcgtcggagt gctgcttcat gacgcggttg tgggcgtcgg
     7141 cgttgcgggc gtagccgtcg taggtgccga cgaccgcggc cagctcggcg gagcggcggt
     7201 aggccgtacc cgtcatcagg gaggtgatgc cgccggccag ggagcggccg ccgtccgagt
     7261 cgtaggcgtg gccggtggcc atcagcaggg cgccgaggtt ggcgtagccg atgccgagct
     7321 ggcggaacgc ccgcgtgttc tcgccgatct tctgggtcgg gaagtccgcg aagcagatgg
     7381 agatgtccat cgcggtgatg accagctcga cgaccttctg gaagcgctcg gtctcgaagg
     7441 actggtggcc cttgccgtcg tccttgagga acttcatcag gttcagcgag gcgaggttgc
     7501 aggacgtgtt gtccaggtgc atgtactcgc tgcacgggtt cgacgcggtg atccggccgg
     7561 actcggggca ggtgtgccag ttgttgatcg tgtcgtcgta ctggatgccc gggtcggcgc
     7621 aggcccaggc cgcctcggcc atccggcgga agagggactt ggcgtcgacc tcctcgatga
     7681 cctcaccggt catacgggcg cgcaggccga acttgccgcc cttctcgacc gccgtcatga
     7741 actcgtcgtt gacacggacc gagttgttgg cgttctggta ctggacggac gtgatgtcgt
     7801 cgccgcccag gtccatgtcg aagcccgcgt cgcgcagggc gcggatcttc tcctcctcct
     7861 tgaccttggt ctcgatgaag tcctcgatgt cggggtggtc gacgtcgagc acgaccatct
     7921 tggcggcgcg ccgggtggca ccaccggact tgatggtgcc ggcggaggcg tcggcgccgc
     7981 gcatgaagga gaccgggccg gaggcgttgc cgccggagga gagcagctcc ttggaggagc
     8041 ggatgcggga gaggttcagg ccggcgccgg agccgccctt gaagatcatg ccctcttcct
     8101 tgtaccagtc gaggatcgac tccatggagt cgtcgacgga caggatgaag caggcggaga
     8161 cctgctgggg ctgcggggtc ccgacgttga accagacggg gctgttgaag ctgaagatct
     8221 ggtgcaggag ggcgtaggcc agctcgtgct cgaagatctc ggcgtcggcg ggcgaggcga
     8281 agtacttgta gtcctcaccg gccttccggt acgtcttcac gatgcggtcg atcagctgcc
     8341 tgaggctgac ctcgcgctgc ggggcgccca cggcaccccg gaagtacttg ctggtgacga
     8401 tgttgaccgc gttcaccgac cagaagtcgg ggaactcgac gccacgctgc tcgaagttga
     8461 ccgagccgtc gcgccagttg gtcatgacga cgtcacggcg ctcccagctc acctcgtcgt
     8521 acgggtgcac gccgggggtg gtgtggatgc gctcgatgtg cagccccttg ttccccgcct
     8581 tgccgccctt ggctcgggaa cctcgtgccg gaccgctcgc cgtctctgtc atgccgcctc
     8641 cctggtacgg gcaaaacgcc ctgaagtgcc gcgtatgttc ccgtggcacg gtgttctgtc
     8701 gtgtgttgcg ggcaccctca gctagccacc cgcaacaggc cttgtgtcgg ccgcctcccg
     8761 gccggaaccc gggtctcctc ccggttcccg gcccgccggt cagtcggcgg cgtgggcggg
     8821 cgccggaacc tgggtggtcc cgccgggccc gcagtctgct tcctggtcca ccgctcccgc
     8881 gtccgcgtcg tccgcggcgg ggcctcgcgt gacgtccctc agctcagcga tcgcggcctc
     8941 gaagtcgtcg agcgagtcga acgcccggta gacggaggcg aaccgcagat aagcgacgag
     9001 gtcgagttcc tgcaaggggc cgagtatggc caggcccacg tcgtgggtgg tcagctcggc
     9061 gctcccggtg gcgcgcaccg cctcctcgac ccgctggccg agctgggcga gtgcgtcctc
     9121 ggtgacaggc cgtccctggc atgccttgcg cacgccgttg atgaccttgg cacggctgaa
     9181 cggctcggtg actccggacc gcttgaccac catgagcgag cacgtctcca cggtcgtgaa
     9241 acgacgggag cagtcggggc actggcggcg cctgcggatc gacgtgccgt cgtcggtcgt
     9301 acggctgtcg accacacggc tgtcgggatg cctgcagaag ggacagtgca tgatctccaa
     9361 ccctcctcac agcagtctca ttgacctcac cggacccgca ggccccacga agcagcctta
     9421 agcataggcg atcgccaagc tgtctccgac ccgggggacc acaacttatg ggctgctgta
     9481 gccatccaac cactagatgt ggggattgac tcatacatac aggcgaagac gcgtgtcgcg
     9541 accggacggc agatcccggg cagccgcgga ggccggccgg acacgcgccc gcgtaccccc
     9601 gccgtcgtga cgcatacggg gatagcgtgg acgccgcgcg gaggaggcgt ggcactccga
     9661 cggcactccg acacggaagg accccggatc ccggactgcg gggttccgga tgacagactg
     9721 gggacgcggc ccacaaggtc ggcgaccccg gcggtgaaga gtacagcaat gggcgctttt
     9781 gtccgcgagt gtcggctgag ccatacaccc acacacgcga tcgcgtcgcg cgaaacgcac
     9841 tttttcactc gaacgtgtgt ttggcgcaac ctttcgaaag caactaccgt tgtgcagcag
     9901 ggagaccatc gagaggggcc gccgtgacca ccaccgcaga cagtgccacc atcaccgccc
     9961 aggatcgctc ccagggccga gtcgagccgg tgcacgtgat gaacgaagtg acgaatcccg
    10021 agggacacaa acgctccctg ccgggccgac ctcccggcat tcgggcggac agctcgggcc
    10081 tcacggaccg gcagcgccgg gtgatcgagg tcatcaggga ctcggtgcag cggaggggct
    10141 acccaccgtc gatgcgggag atcggccagg ccgtcggtct gtccagcacg tcctcggtcg
    10201 cccaccagct gatggcactg gagcgcaagg ggttcctgcg tcgcgacccg caccgcccgc
    10261 gcgcgtacga ggtgcgcggc tccgaccagg ccgtgaccgt gcagcccacg gacaccgccg
    10321 gcaagcccgc cgcgtcctac gtcccgctgg tcggccgtat cgcggccggt ggccccatcc
    10381 tcgcggagga gtccgtcgag gacgtcttcc cgctcccccg ccagctcgtc ggcgacggcg
    10441 aactgttcgt cctgaaggtc gtcggtgact ccatgatcga ggccgcgatc tgtgacggtg
    10501 actgggtgac cgtgcgtcgc cagccggtcg ccgagaacgg cgacatcgtg gccgccatgc
    10561 tcgacggcga ggccaccgtc aagcgcttca agcgcgagga cggccacgta tggctcctcc
    10621 cgcacaacgc ggcctacgag ccgatccccg gcgacgacgc gacgatcctg ggcaaggtcg
    10681 tcgcggtgct gcgccgcgtg tgacgaacgc ggcaggcggg ccccgtcggc tcgctccctg
    10741 accgggcccc ggaacctctg cgccggttcc ggggtcctgc ctgtctctgg gcggccgcac
    10801 gggcggctgc cctcgtgggt gctccggccg gctcggtcgg accaccccac ggtcacgtcg
    10861 ccgcgtgctg cgtctctgcc tgctccgctt cggcttgccg cgtctccacc tgctgcgccg
    10921 ccgcgtcgat cgccgccagc gacctgcgga cctggttacg gtccgtggtg taccagaagt
    10981 ccggcaggga cgacttcaga tagccgccgt agcgcgcggt ggccagccgt tggtccagta
    11041 cggcgaccac accccggtcg ccggacgccc gtacgaggcg tccggcgccc tgcgccatca
    11101 gcagagcggc gtgtgtcgcg gccactgcca tgaacccgtt gcctcccgcg tcctccaccg
    11161 ccttctggcg cgcgctcatc agcggatcgt cgggacgcgg gaacgggatc ttgtccatga
    11221 cgacgagctg gcagctgggt cccgggacgt cgacgccctg ccacagcgac agcgtgccga
    11281 agagacaggt cttggggtcg gccgcgaagt tcttgatcag ttcgccgagc gtctcctcgc
    11341 cctggaggag gatcgggaac tcggggatcc gggagcgcag ctcctccgcc gcgagctggg
    11401 cggcccgcat ggacgagaac agcccgaggg tgcgaccgcc ggccgcctgg atcagctcgg
    11461 tcagctcgtc cagcatgtcg gtccggtcgc cgtcccgcgc ggggcgcgcc aggtgcttgg
    11521 cgacgtacag gatgccctgt ctgcggtagt cgaagggtga gccgacgtcg acgcccttcc
    11581 acttcggcag gtcctcgccc tccgcgccct ccgggccgag ccccagggag gccccgaccc
    11641 cgttgaagtc gccgcccagc ttgagcgtcg ccgaggtgag gacgacggca cggtcggcga
    11701 agagcttttc cctgagcagg cccgacaccg acatgggggc gaccctgagg gaggcgccga
    11761 aacggtcgtg ccgctcgtac cagacgacat cccactccga gccgttcacg acccgctccg
    11821 ccacgtcgtg caccgactcc acggaggcga gcgcctgctt gcggaccgcg tcctcgtcct
    11881 ggacggactt gtcgcgtgtc gcgccgatcg ccgagatgac cgtacgggca gcgtcccgca
    11941 gcgccatcag ggcgtagccg aggtcttccg ggatctcctc caggcggccc ggaagcgcca
    12001 gctccatgag ccgctcgaag ccctcggcgg cggtctggag ctggtcggcg gccttctcgt
    12061 tgacgagctt ggcggctcgg cgcacggcac ggttgacctg gccgggcgtg agttcgccgg
    12121 tggcgacgcc ggtgacacgg gagacgagtt cgtgcgcctc gtccacgatc agcacctcgt
    12181 gctggggcag caccggggcg ccctcgatgg cgtcgatggc cagcagggcg tggttggtga
    12241 ccacgacctc ggcgagcttg gcgcgctcgc gcgccatctc cgcgaagcac tcggcgccgt
    12301 acgcgcactt cgacgcgccc agacactccc gcgacgacac cgacacctgc gcccaggcgc
    12361 ggtcggagac acccgggctg agaccgtccc ggtcgccgct ctcggtctcg tccgcccagt
    12421 cacgcagccg caggaggtcc tggcccagct tgctggtggg cgcggcggcc tcgaactggt
    12481 cgaagagccc ctcctcctcg tcctgcggca tgccctcgtg cagccggtgc aggcacaggt
    12541 agttcgaccg gcccttgagc atggcgaact ccggacggcg gcgcagcagc gggtgcaggg
    12601 cgtcgaccgt gcgcggcagg tcgcgctcca cgagctggcg ctggagggcg agggtggccg
    12661 tcgcgacgat cacccgttct ccgtgcgcca gcgcgggcac gaggtagccc agcgactttg
    12721 gtgccggtgc cggcctggac cagcaggtgg gatccgtcgt cgatcgcctc ggcgaccgct
    12781 tcggccatgg tgacctggcc ggggcgctcc gtaccgccga cggcggcgac ggcggcatgc
    12841 aggagttcgg gaagtgaggg cttcgtcata gcccgaccac cctacggccc tgcactgaca
    12901 aacggggtct cgtggcgggg gcggggggcg ggatcacggc cggggctcct ggtggtggcg
    12961 gggggatcgg cggggcggat ctgaggggcg gggtcggagg ggcgggtcgg agagaggggt
    13021 tgccggggcg cgatatgggg cgcggaattt ttttcggccg cgggaacacc gcggacccgc
    13081 ggttcgtatc tccatgtgag tgcttgatgg cggagtgcta cagcacatgg cgcaggaccc
    13141 ggtcccggat catgagggcg gcccgcttgg caggcaggtc gacttccgcc gcgtaccgga
    13201 agcccgcgct caggaacgcg gccacggagg gggtgttgca cagatcgggt tccgctacga
    13261 cacgtgcgca tgcgggacgc gccggtcgag gatcaggtcg gccacggctc ggagcagggc
    13321 ggaccccagc cctcgtcccc ggtcggcggc gtcaccgacg aggaggtgga tcccggtgtc
    13381 gtgcggacgg gccgggtagt gacgggccag cgggtcgagg tccgcgcggt agatctccca
    13441 ataactcatc ggggtgccgt tcagtacgcc gaggcacggc acgctgtgtc cgtcgccggc
    13501 caattgggtc cgcagatgct cctcggtccg gttccggggt ccggccagtt cccagaagga
    13561 ggccacggcg gagtcgttca tccagcggtg gacgagcggc aggtcgtgct cgatgcgtac
    13621 gggcagcagg cggaaggtgc cggccgaggt ggtgaccggc ccccaggcgg agagccggtc
    13681 gggcgtgccg actgtcgttc cggcgcagaa ggcgatgaag tcggcgggca gacgcaggtc
    13741 cagcgtgtcc tcgctgtccg ggtcgtcgtc ctcgacggtg aacccgcgaa agcgtgagcc
    13801 acgaaggccc gcggcgtccg ttccggggcc ggcgcagccc tggtgggcag gggcggggct
    13861 ggtcgcggcg ccggcgtcgg tgggaggcac ggtgcgctcc tctcaggagg cgaggtgggt
    13921 catgttcctc ggttgtgcgg gaagacggtg cggctcgccc ggggcgcggt ccgctcaggg
    13981 ggtgccctgc ggtgttgtgc tcaggaatgg agggggttgg cgatggtgac gtagacggac
    14041 tgggtgtcga ccgggccgac gagttcgtcc aggccgtaca gccgggtcag cagattggcc
    14101 ttgcagcgca ggacgggtga gtcgaggagg cgggcgagca gggaggagcg cagcgcggcg
    14161 ggtcccgtgg cgagctcggt gaggaagcgg cggaaggccg cgaggagcag ccgctcgtcg
    14221 gcgaggtgct gggagccgaa ggcgccgatc agtcccagca cgttgttgac ggcgaggtag
    14281 taggtgaacc gttcgtcggt gacctcgtcg gggacgaagg tgtcgctgtg ctcaccgatg
    14341 ccgggcagcc gggcctccag ttcggcccgc cgggactcgc ggaagtagta cccctggttg
    14401 tcgcggtagc ggccgccggc gggccagccg tcgcggtcga gcaggagcag ggtgttctgc
    14461 tggtgggcct cgagagcgat gccggcctcg ccgtccagcc agagcacggg gcggacgacg
    14521 tgctccagat agcgcaggaa ccactcggtg gcgacggcgc cgaccggccg accggtgtgt
    14581 gcggcgagtc ttgcgacgag tcgttccagc cgggagcgca tcggccaggt cacctgccca
    14641 cgcgaagggt tggtggtctg ctccgcggag ggacgtggcg agagcagtcc ggcgacgcag
    14701 ccggcgtcgt cggccggggc gaacgggttg tgccggatca ccgcgtcgag gcccggcacg
    14761 ggcatgccgt cccggccgtc gacggcgagc caggccgggt cgcggacgat gtcgaagccg
    14821 gggtgcacgg cctgccactg ctcggctagg ccggtgcgca gcagccggtg cacctcgact
    14881 ccgcggtgga gttccttgcg caggttctcg cggcgggagt tggtgatgcg caggcccagc
    14941 gacagtttga gcatcgcggg ggcgccggac cggtggacgg ttcgtacgga ggaggtggga
    15001 tgccagtcgg cgccgagggg gccgaggtcg cgcagaagtc ctgagtcgag gagtgcggcg
    15061 acggacggac ggtgccgaac ctcgcgggcc tgccaggggt gcagcggcag ggcggtgtaa
    15121 ccgtcgggca gcgggagccc ggttccggcg agccgtcgga cgaggtggcc ggcggggacg
    15181 ggacggccgc gttcggtcca ggcggagtcg gttgcgagga cggaaggagc gacagccagc
    15241 cagtgcaggg ggaaggagcc gtgcagctcg ggtgagtacc gctgggcctc ggcctcggtc
    15301 aggccttccc ggctcttcgg ggtcgggtgc agcgggtggc cgaggaggag ggactgttcg
    15361 gcgctgagga agaggtcggg agcgtcggcg gggtggtcgc gccgatggcg gatgaaggcg
    15421 gcggtgcggc ggacggagtc ggccacccgc gccaccaggt cgtcgtcgcc tcggccggcc
    15481 gcggtgggct gcacggtgcg gatcgcgccg gacgtgtcat ccgctggttc cctgacgagc
    15541 agtgccgcga gtgtgacggc gtcgacgggc ggcgccgtct cgggagtgcc ggtgagacgg
    15601 ggcgggccga agcggtgcca gcccgtcggg gaccagtagc ggaccggcgc ggtcagggcg
    15661 gtgccgctgg cgggcagcgg gatgcggagg ctgccggtcg tgggggctgc gaggccggtt
    15721 tcgcgcaccc agcaacgcag gaggttctcc acggcggcgg cctgggccgc ggtgcgggga
    15781 tcggggctct ccagggggtc ggcgccgggc tcggtccgtc gcgtgaggtc cgcgtcccgc
    15841 cgcttctgcg gggggaccga ctcggtgagc ggtaccggtg tggccggggc gccggagcct
    15901 cccggttcgt cgggggcgcc ggagtggccg tcgggagtgg gtgtggcgtt catgacggct
    15961 cctcggggct ggaggtgagg tggtgctgct cggtcggtcg tccgctgggt cgccgcggcg
    16021 cctggacggt ggttgccgga gcggtgactc agtggaaggc gaggtgagcg ggacgtgcac
    16081 gtgatggctt tgcggtcggc gccgacgggc ggcgtcggcc cggatgcccg ggagggggct
    16141 gggatgaggg gacggagtga cgacctgggg accggtgtcg aaggcgcggg ccgggcgggg
    16201 cgccggcggt gctcagcccg cgcgttcggc ggggccgtgg cggccttggt ggtgtgggcc
    16261 gtgggactca tgccggcggg ccgctgccgc caccgcgtcg gccaggcggt cgagtacggc
    16321 cgtcgcctgt tcgtcagtga tcgtcagcgg aggaagcagc cggaccacgg ccgcgtgacg
    16381 gccgccgagt tccacgatca ggccccgctg gagacactcc cgctggacgg cggcggcgag
    16441 tcggggcgcg gcggggtgcg gagtgcgggt gggttcgagt ccggccggtg cggcgacggg
    16501 atgcggcgcg tgcgtgggtg cccgtccagt cggtgcggcg acgcgctcac ccggggcgga
    16561 agcggaaccg aggacggtgc cagaaccggg ggcggaaccg ggggcggatc cggaaccggg
    16621 ggcaattgcg cagccgggga cggtttcgga gccgggcgcg gttcccccgg ccccggggtc
    16681 gaccagttcg agcccgatca tcagcccgcg tccccgtacg tcgcccacgc aggggaagtc
    16741 gcgggccagg tcctggagtc gggacagcat gcgggcgccg agggcggcgg cgcggtcggc
    16801 gaggccgttc tcgcggacgt aggcgagggt ggcggtgccc gcggccatgg cgagctggtt
    16861 gccgcggaac gtgccggcgt gggcgccggg ctgccagacg tcgagatcgt cgcggtagac
    16921 gatcacggcg agggggaggc tgccgccgat ggccttggac aggaccatga cgtcgggggt
    16981 gatcccgctg tggccgacgg cccagaagct gcccgtccgg ccgactccgg tctggatctc
    17041 gtcggcgatc agcgggatgg accggtccgc cgtgagctgt cgcatgcggc gcagccagtc
    17101 gtccggcgcg ggaatcacgc cgccctcgcc ctggacgggt tcgacgatca tcccggcggg
    17161 caggggaacg cccgacttgg ggtcgtcgag gagggattcg gtccagcggg cggcgagttc
    17221 ggcgccgcgc ggaccgccga cgccgaaggg gcagcggtag tcctgcgggt agggcaggcg
    17281 ggcgacctgg acgtcggggg caccgccgga gacggccagg gcgccggtgg tcatgccgtg
    17341 gtaggcgccg gtgaaggcga gcatgccggt gcggccggtc gcggcgcggg ccagggtgag
    17401 ggcggcctcg acggcgtcgg tgccggccgg tccgcagaac tgcacgcggg cacggtcggc
    17461 gaggccgggc ggaagcgtgc ggaacagctc cgtgacgaag gcgtccttga cgggggtggc
    17521 caggtcgagg acggagaggg gggcgccgga gtcgaggacc gcgcggatgg cctccagcac
    17581 caccgggtgg ttgtggccga gcgcgagggc gccggcgccg gagaggcagt cgaggtagcg
    17641 gcgtccgtcg gcgccctcga cggtgagccc gcgcgcccgg acgggcacga cgggcagggc
    17701 gcgggcgtag gtgcgcgccg aggactcacg cgccgactgg cgtctgagga ttccctcgtg
    17761 cacggcccgc gctcgcccgg gtgtgtctcc tgccaccgac tccgtaacgg ccacggcgtg
    17821 ctgtcctccc cgctgtccag aggcgagttg atccgcgggg accgggtgaa gccggcagtc
    17881 cccccaccgc ctacaaccgc ggaccgtgcg gcgggttacg ggttgggccg agatcggtgc
    17941 cgtgactgcc ggagggtggc gcgccgttcc ggttcggcgt ccgtgccgtc cggggcgcgg
    18001 tccggccccg gcccggcgcg ggaacgccgt ccggggcccg ggccggtgga ccgctcagtg
    18061 cgccgtctgc ggggtccgcg ccttcggcga ctgccgtacc tccgcggcgg cggccacgac
    18121 gtcgtccagc agcgcgtcga tgtcctgcgt ggtggtggcc gggttcagga agaccagctt
    18181 caggtgcacc tgtgcctgcc cgtcctggcg tcgtaccttc gtgcgggcca gcagggcctt
    18241 gccctcggcc atcaggtgcc tgcggaccgc ggcgttccag gtgctctcgt cctcgatcgc
    18301 cgcaccggcc cggcagcgga agaccacggt gctgaggatc ggttcggcga gcagttcgag
    18361 gtccgggtcg cgggtgatgc gggcggccgc gtaccgggcc tgggagtggc aggcgtcgac
    18421 ccattcgccc atgccctcgc ggccgagggc cagcagcgag gccgcgatct tgaaggcgtc
    18481 ggcgcggcgg gtggtctgga gggaggtgcc gagcagcgcg gtgtagccct cggcctcgtc
    18541 gtccggcggg ttgaggtaga cggcctgctg gccgagcggg ctcatccggg cccggtcccg
    18601 taccagcaga atgctggagg aggcgggtgt ccagccgaat ttgtgcaggt cgaaggcgat
    18661 ggagtcggct tcggccagtc cgtcgaagag ggggcggagc gtgtccgaga agagggcgcc
    18721 gatgccgtac gccgcgtcga cgtggaacca gatcctgcgt tcggcggcga gggcggcgag
    18781 ttccggcagt gggtcgaagg agccgtggtc cgtggtgccg gcggtggcca ccagcgcgat
    18841 ggggacctcg tcgggggcga atccgtccag gagccggcgt gcctcctcgg ggatcatgcg
    18901 gcctcgttcg tcggcgggta cccgcaccac cgcgtcccgg cccagcccga ggaagccggc
    18961 ggcgcgtgcg acggagaagt gcgcggcggt cgagcagagg atccgcggcc gtatcgcgcg
    19021 gccggcgagt ccggtgtggg agatgtcgtc gccggtgagg ccgccgagca cgtggtcgcg
    19081 gctgagcagc aggcccatga ggttggagat gctgccgccg ggggtgagtg tgccggaggc
    19141 cgtctcgccg tatccgaccc agtcggccat ctcggcgatc agccggcgtt ccagttcgag
    19201 ggcgaagggg ccgctctccc aggagtgcag cgactggttg aggacggcgg cgaggagttc
    19261 ggcggcagcg gcggcgggtg tgggcgcgca ctgcatccgg gagacggcgg ccgggtgggt
    19321 caggtcggcc gcccagcccg cgtacgcctc gaacagctct tccacccggt gcgggccggg
    19381 tgcgtcggtg aggaagccgc cgtcgcgcac caggtcgcgt accgcggcga tcgccgcgtc
    19441 ggggccgccg gccgggagcg ggccggtgcg ctcggccgcg gcggcggaca ccgcgtcgag
    19501 ggcggcggtg accagcgtgc cgagctgctc caggccgtcg ggggtgcccg ccagggccac
    19561 gcggtgcccg gtgccggtgg tggcgggggt gctgtggttc acggatcgca tccttctgtc
    19621 gggttcgggg gtggcgcggg agcgggttca ggtggtggcg cgggtgccgc ggatgacgcc
    19681 gatcgacgcg acgaccacgg aggcgagccc caggacctgg ccggcggaga gggtctcgcc
    19741 cagcacgatc agggcgacga gtgcgccgat cgccggttcc aggctcagca gcacgccgaa
    19801 gaccagcgcc ggcacccggc gcagcgtctc catctcgcag gtgtagggga cgagcgagga
    19861 cagcatcgcc acgccgaacc cgaaggcgag cgcccagggg tggcccagga ccgagccgcc
    19921 ctcggccagc ccgaacggca gcgcgcacag ggtgccgaag agcatggcga gggcgagccc
    19981 gccaccgccc gggagctggg ctccgacccg ggcggacagg gggacgtagg cgccccagaa
    20041 cacggcgcag gcggcggaga tcagcaggcc ggcgaggccg gtggcgccgc cctgccagcc
    20101 gagcagggcg ataccggcgc cggccagcag ggtccacatc cggtcacggc cccgccggct
    20161 ggacagggcg gcgaccatga gcggccccga catgccgatg gtgagcgcca cgccgacggg
    20221 caggcgggcc atggccaggt agaagcacat gttcatgccg gcgatggtga tgccgaggcc
    20281 ggccaccgcg agggcggtgc gccgctccag ccggaaggag ggccgccacc acagcagcag
    20341 tgcggcggcg gcgaagccga ggcggaggac ggtcatgacg gcgggtccga ccgtgccgaa
    20401 catctgcttg gcgaaggccg cgcccagttg cgtgctgacc atgccgatca gcatgagcac
    20461 cggggccggg accaggccga gtccccgggc accggggtcc gccgcgcccg gtgttccggg
    20521 tggggcggcc tcggcgggct gtgctccgac tcccgcttcg acactcatgg ttcagccttc
    20581 ctcgtcgcct gtctcgtccg tcggttccgt ccgtccgctg ccgcgccctc aggggcgcag
    20641 caggaccttt ccggtcgtgc cccggccctc cagcaggtcg tgggcgcgcg ccgcttcgga
    20701 cagcggcagc tcggtctgga cccggggccg tacgacgccg tcggcgacgt gggtgaagac
    20761 ggccgcggcg gcggcgcgca gggcggccgt gtcgggcacg tggtcggcca gggacggccg
    20821 ggtcagggtc agcgagccgg ccgtgcgcag ccgttcgacg tcgatcgcgc cgaccggacc
    20881 gctggagagg ccgcagacca ccaggtggcc ccggcggcgc ggcgcggcca ggctctggtc
    20941 gaaggtgtcg gcgccgaccg agtcgtagac gacgtgggcg ccctcgccgc cggtgagttc
    21001 ccggacccgc tcggcgaagc cgtcgtacgg cagtgcgtgc cgggcccccg cgtcgagtgc
    21061 caggcgctgc ttgtcctcgg tggaggccac ggcgatgacg gtcgccccgc ggtgggcggc
    21121 gagctggacc agcagccggc cgagtccgcc ggccgcggcg aggacgacca cggtctcgcc
    21181 ggcggtgacg gggtgcgtgg tgtgggtgag gtagtgcgcg gccaggccct ggagcagtac
    21241 ggcggccgcg tcgcggaggt ggatgttctc cggcacgggg acgagcttgg ccgcgggtac
    21301 ggcggtggac tcggcgtagg cgccgagctg ggtggcgtag gcgacgcggt cgccgacggc
    21361 gatgccctcg acgccctcgc ccaccgcggt gacggtgccc gcggcttcct ggccggggac
    21421 gaacgggcag ggtgcggggt aggtgccgtc gcggaagtag acgtcgatga agttgagtcc
    21481 gatcaccgcg ttgcgcacca cggcttcgcc ggccgcgggc gcgggctcgg gcagttccac
    21541 gggggtgaga gccgcggagc cgcctgcccg ggtcacctgg attgcgcgca tggatacctc
    21601 acttgctcac ggggatgccg gcaccggtgg tgccaggtga tccggtgccg tccgtttcgt
    21661 cgaagacggt gcggaagtag ttgatgtcgc cggtgaggcc ggccatcagg gagccgaggg
    21721 ccacctccgt gccgggccgg gccgcgagca gttcctcgtt gcggcggcgg ttggccgcgg
    21781 agaacggcag ggagccggcc gagagatagc ggatggcgcc ctcggcgtcg cgccggggga
    21841 tgacgtcgga gcgggcgtag cggctcgcgc tgaacgggat gtccagggcg ccccgttcga
    21901 aggcctcggc cgccgcctcg atgaggtccg cgcgctcgat gagggggtcc acgaggtcgc
    21961 cgacctcggc gaggatccac tccatctcct cggcgacccg cgcctcgtcg acccggagga
    22021 agtccagcag tggggagttg gcccggtccg cgagtcgcag tccctccacg ttggcccggg
    22081 tgtcggggat gccgtaggcc tcctggtagg tcttggtgat gagcttggag gcgccgccga
    22141 ggcgggcgac caacgcgccg tagagaatga ggtcctcggc gttgccccgc tgccggggga
    22201 acacgcccat gaactcgtgc agtacggcgt gcacgtcgat gccggtgggc aggtagcgct
    22261 cggcgaggac ggggatgcag cgcagggccg cgatgtcctg ggcgaggtgc ccgccctggg
    22321 ggtaggcgac ggagatgcag cgcacgccgg cgcgtgcggc cagcaccgcc tcgacgacgc
    22381 tgatggccag gctgacggag ggcggtacga ggacggcggt gagggtgccg aacagctccc
    22441 ggtcgatgac gacgccgagt tcggccagtt cgccgcagcg gcggtcgacg tcctgccagg
    22501 cgccgaggga ctcggtgagc gggacggcct tggagtacgg caggttgtag gagatcccgc
    22561 cgccctcgaa ggaggtgatg ccggaggcga cggagacgtc gaagagccgc cgggcgtccg
    22621 gtgagccgtg ccggatctcc aggggtgcgg cgacggactc gttcagctcc cggccgcgcc
    22681 gccagccgtg ggcgaccagc gggtagccgt tgaggtcggt ggggcgcagg ttgaggctgc
    22741 gcagtgcttc ctcgaaccgc ttgagccggg tgtgcgagtc gatggtgagg gtgaggatgt
    22801 cggggtgcgc ctcggcctcc agggcgcgca gcaggtccgt catctcggcg tgtccgccga
    22861 ccccgcagcg cggctggatg gcgacccggc ccgcggcccg gcagcgttcc aggacctcgg
    22921 cggccgtggg tttgccgagg ccggcgatgt aggcggcgga ctcggccgcg gtgggcaggt
    22981 cggcggccgt gtccccggcc gggcccttcc cggcggtgcc gccgagaagg gccaggggct
    23041 tgtgcgtacc ggtcatgacg ccgtgcgcag ggaggcggtg gcgccgtccc gggtggcgcg
    23101 cagcccgtcg aggagcgcgg ggagtccgtc ggggtcggac aggatgtggt cgacgccgag
    23161 ggcgtggaga cgctcgtacg cggagccgtc cttgtggctg ccgacggaga ggttcccgcc
    23221 gacgacgacc gggcagttga tctttccgga gcgcttggtc tccgcgagtc cgcgcaggtc
    23281 ctcgtggata tggccgttga ggctgccgat gatgaccgct tcggcgtccg ggtgggcggc
    23341 gcacgcctgc gcgaactcct cgacgggtgt gcaggtgccg aggttgacca cgtcgaagcc
    23401 ggcgccgcgc agcgcgtagg cgatcaggtg gttggccacg gcgtggctgt cgctggcggc
    23461 caccccgagg atgaccgtgc gggtgggggt tgcttgcttg ctctgcatgg acctgtttcc
    23521 tcgtcccacg tggtggtcgt cagtcgtcga aggccgcgaa cagttcgcgc ttgctgaccg
    23581 ccttcagccg gttgatgtcg tattcctggg cgtccgcgcg ggacagcgag tcgaagacgt
    23641 ggctgatggc ggggaccagg ccccagacct cgtggtacgg gggccagccc tggtggccgg
    23701 cgtcgatgtc ctgctggcgg gcgaagatgt agttcgccca gtccggcgcg gccgggtagc
    23761 ggtggtggta gtcgtgcacg acggtgtcgc cggtcagcac cagatagcgg cacggggcgt
    23821 gcacgaacac gagccggagg gtccagcggg cccaggcggc gaggcggcgg ccggccggga
    23881 ggccggcgga gggggccggg tcgccgatga agatggcgtt ggtcaggctg gagaagtact
    23941 cgcgtccgtg gcggatctcc acaccgggct cggggaaggt gtgcttcacg cacagccgca
    24001 gggtgttgct cacctggaac agcgggacga gcggcacgaa ccagatcagc agcagggccg
    24061 gccaggtgcc ggtgagcacc gtagcggcga cggcaccgcc gtacagcacg agcgcgcaga
    24121 ccttctcgct gcgggccgac tcgctccaga acgaccgggc gcgggagacg gcgaacgcga
    24181 agtggaagcg cggggagacg agtttgccga gcacccggcg ccacatccgg cggcgcgtca
    24241 tgcccgggtg cagttccagg ctgaccagga acgcctggac cgtggggtcc ttgagcgtca
    24301 tgtgcccggc ggcgtggtgg tccttgacgt gctcgcggct gtagcgctgg aagttctgga
    24361 tgatgagcag gctggacacg ccgtggccga tgaaccggtc gagcttgcgc cgccggtaca
    24421 tgttccggtg ggagcactgg tggtaggtca tcatccgcag gttgcgcatg ccgtgcagcg
    24481 tgatggccca ccccggtatc aggagcagcg gccagccgcc gccgagcgcg tacccgagcg
    24541 tgccgaccag gacaccggcg accacggagg acagtgccgt ggcgaggtgg agggtggggg
    24601 tccagcccgg ggcggcctgg ccgggcagtg ccttgccggt gaacagggtc agggggaact
    24661 gcaacgcctt cggcagacgg gtcagggtct cgcgggggtc ctggggcccg ggcggggaca
    24721 cgggacgtac accggcactc cgaacggcgg agttggtcgc cgacacaaga actcctatcg
    24781 gttccgaggt tgtctgttcg tgggccggcg gatgggcgcc ggcacggctc acagggcgtc
    24841 cgcgacgcgg acggtggcgg cgctcatcag gcggcactgg caggccaggc ggtagttgcc
    24901 gccggtctgg ccgaggtcct ccaggaagtc ggcctcttcg gggtccatct cgcccagcgc
    24961 gtcgaagccg tcgaggacct cgatgacgca ggccccgcac gccccctgct ggcagccgaa
    25021 cgggatgacg cgctgtgagg tcccgcgctc gaggtcggtc agcggtgacc cggccggcag
    25081 ttgcacttcc aggccgtacg gcatcagggt cagtttcttg agatccattg ctgcggtggc
    25141 tccctgaggg catgtcggtt ccccggcggg gccgggggcg ggttcggtcg gccggcggag
    25201 tcggctgttt cgggccccgc gccgtggcgc cgggtggtca cgggccgtac ggccgccggg
    25261 ccgcgggggg cgtacggggg tcaggccacg gcggccggca gcggcggctc cggcgggggt
    25321 accgcgtccg aggagtggcc gggggcgagg cgttcgcccg gccggagtgc cacggccgcg
    25381 tggttgaccg cggtggcggc ctccgcgaag ccgacggaga taaggggcac ccggcctggg
    25441 tgggtgcaga cgtccccggc ggcgtacacc ccgggcagat tggtgcgcat ggtcgcgtcc
    25501 accttgatct gccggaattc cagctcgacg tcccagtcgg cgatcgggcc gagctgtgtg
    25561 gagaagccga gcgcggtgat cagcgcggag gcgggcagtg tcagcaggtc gtcgccggcc
    25621 cgtacctcca ccgcttcgag ccgccgccct ccgagacacc gcgtgatgag tgcgtcggtg
    25681 atgatccgca cgggtgcggc gtatagctgg cggacgctgt actcgtgggc ccggaaggcg
    25741 gcccgccggt gcacgagggt cacggagcgg gcgacggggg cgagggcgag cgcccagtcc
    25801 accgcgctgt cgccgccgcc ggcgatgacg acgtcccggt cgcggtgctc gtccagcctc
    25861 ggcacgtggt gcgtcacccc gcggccctcg tggtccgcgg cggccggcag cctgcgcggg
    25921 acggcggcgc cgaggccggc ggtgatgagc acggcaccgg cgcgcacaca cgcgccgcgg
    25981 tcggtcccaa gggtccagcc ggtgccggtg cgggcgagcg tggtggcggt ctggccgagg
    26041 aggtagcgtg gttcgaaggg cgccgcctgc cggagcaggt tctccacgag gtcgcgtccc
    26101 ttgatggcgg ggtgcgccgg gatgtcgtag agcggcttct ccgggtacat ggcggccacc
    26161 tgtccgccgg cgtgcggcag ggtgtccagc acggcggtgg tgaggccgcg gaatccggcg
    26221 tagtaggcgg cgtggagtcc gctgggcccg gcgccgacga tggcgaggtc gacgtccgaa
    26281 tcgattgaag cgggcatgtc aagctccttg tccggggacg cgggccgacg cccattccga
    26341 ccccacgggc accggcatca ccgcgagccc cgtcgccggc gccaccacac cgccgacctc
    26401 gccggcgccc cgagcgtcac cgccaccggc gcgaccggca ccaagcgcgg cgcatgcgct
    26461 ccgcacgcgt cccgtaccgc tcacatccgt gactgccacg acccactccc ccgttcctgc
    26521 cccgttcccg tccagttcgc ccaggagccc gttcgccccg gtcgcacgga agccacagac
    26581 cgtcaccggc catcgactga tcgaaagagt agagaacgtt cgctatgttt ttcaagggcc
    26641 agtcgattcc gattcccgtc gctcgcgacc ggacggcacg cagaatcaat caacggaggg
    26701 acgcggcacc ccggaggacg acctcccaca cgcgttccag ttgcgaggcc gcccccggcg
    26761 cgggcggcgc cccgaacacg agatggttca ccagaacggt catgacctgc ggatccacgc
    26821 ccgcccgcag ctccccggag cattgcgcct gcgccagcag ccggcgcacc acgggaagcc
    26881 aggtgctcac ccacgcgtcg tcgtccggac agtcccgggc gagccgggcc gcggaccgca
    26941 cgaccacctc agtctccagc agatgcgcga gctggacggt cagccggacc aggcagggca
    27001 acgcggcacc aggggcgctc gccgcgtcca ccgcctgccg catccggtcg tgggtgaggg
    27061 tgcgggcgtc ggcgcgtacc gcgtcggcga ggtcacgttt ggagctgaag tgaaaggtca
    27121 gcgccccgat ggacacctgg gcggccttgc agatgcgggc cagggtggcc ccttcgtaac
    27181 cgctctcggc gatcgcggtg gcggcggcga acaccagccg ctgccgggtg cgggcggatc
    27241 tctcctggct ggccatgagg cacctccggt acgcgggatc gaataaaagc aatcgttcgc
    27301 tttattttcc agtccctgtc gggcgtctcg gcaaccgcac gtcccggtgc acttcccgcc
    27361 cggatacgac gaggggggcg accccggaaa gccgccccct cgagaacccc ggccggccgg
    27421 gcaccgcccg cgtcggctca gaccgccgtc cggccgccgt cgaccggcac cgccgcgccc
    27481 gtcacgaagg ccgcccggtc gctgcacagc cagaccgcgg cctgggcgat ctcatcgggc
    27541 gaggccatgc gccggcgcag cgtgcgcgcc tcaaaacgtt cctcgacctc ccgcgacccg
    27601 gcgatgacct ggtccatcat ctcggtgcgc gtgctgccca cgaccagcgc gttgaccctg
    27661 atcccgcggt cgccgtactc gcgcgcggcg gcccggctca ggccgatcac cgcgtgcttg
    27721 gcggccacgt acgcggcgga cgcgctggag gccagcaccc cggcgacgct ggaggtgttc
    27781 acgacggccc cgccgccgga ggcgagcatc accgggagct gccggcgcag gcagttccag
    27841 acgccgcgca cgttgacgtc catggtgcgg gcgtagtcct cgtcgtccat ctccagcagg
    27901 ggcgtgccga cggtggcgta accggcgttg ttgaaggccg cgtcgagtcc gccgaaggtg
    27961 tcgacggcgg ccgtgacggc ccgttcgacg tcgtcggacg agcagacgtc gccctcgacg
    28021 gcgagcgcac gtccgcccgc cgcacggatc tccgccacca gttgttcgag gcggtccccg
    28081 cgccgggcca tgaggaccac ggcggcgccc tcctcggcga acagccgggc cgccgcggcg
    28141 ccgatgccgc tggacgcgcc cgtgatcatg gctaccttgc ccttgagcat gtcagtcccg
    28201 ccagacggtg ccgagcgccg cttcttcgtc cagggtccgc agcagttcct cgtcgacggc
    28261 gtccagggag tccacgatgt gccgcacccc ggcctcgcgc atcagctgcg gctggaaact
    28321 gtgccggaag tcgctggggt ggccgatgaa gggcacgccc agctccctgg cggcacggcc
    28381 gacgttcgcc acgtcgtcga tgaagagggc ctcgtcgtac ttgaggccga agtactcggt
    28441 gacgatctcg tggacaccgg gccggaacgt gtcggtgcag atgtacccgg ggtcgtcgaa
    28501 gaggtccgcg tacgggccga ggaacgtgtc gaagtgctcc ttgtcgaggc cgccgtagca
    28561 gaccgtccgc agaccggcgg cgcgcagccg ccgcaggagt tccaccgcgc cctcgtcgag
    28621 ccgcgcgggg tgggtctcca gatactccgc gcggtcccgg aagtacagct ccagcgcggc
    28681 ttgtggggtg acggatccgc cgatggcctc ggccaggagc cggcctgcga ccgcgcgtgg
    28741 ctgcgagaag atgctgcgtt ccagttcggc cgtgtagacg cagccccggt cgaccaggaa
    28801 gcggtggatg accgggctga aggtgtcgtt gagcaggacg ccgtcgatgt tgaccgcggc
    28861 caggcgtagc cggttgagcg tatgaaccat gggttactcc ccctacggtg gcgcgaaccc
    28921 cgccgggcgc ccgaacggcc ccgcgggaca gacctgtcgg gagacagggc gtgcaacgcg
    28981 ggacacctta cgtgcaggtg ttctgacggc cgcggggggc gcgtgatctt gctcggggcg
    29041 cggtggctca gccggtgcca tcgcccgggg cgccgacggg agccgttgct tcctcggccg
    29101 ccagggcgcg ggcgggatcg accgcggtac gggcgaccac ggacggcacg gcgatgcccg
    29161 gcagcaacag ccgccacatc cgcaccaccc ggtcggacag gtcggcgcgg caggtctcgg
    29221 ccgccgcgta catctgcatg ccggtacagg cctcgacgat cagctcggcg agttccgacg
    29281 gctcgacacc ggcctggagt tcccctctct cccgggcggc cagcagacac tcctccatga
    29341 tctggctcca ggcctggtag gggctggagt cgcggagccc gaaggtcgtc tgctcgccgg
    29401 tgagccggac cccggcccgc aacagcgggt cggtctgcag ccggcgcgcc cacaccagtg
    29461 tgatgtcgac cagccgttgc agcccctggg actccaggaa cggcaggatc gtgtcggact
    29521 gggcgttcat cacggccttg gcgagagcct ccttggactc gaagtggaag tacagggctc
    29581 ccgccgtgac cccggcccgt ttgaggatgc ggctgatgct ggcgcccgcg aagccgtact
    29641 cgtcgaagac ctccgccgcc gcgaggatga gcgccccgcg cgtctggatc gccctctcct
    29701 gtctgggttg ccccacgacg ttccctccct agttcaaatg aaacgttctc tatgttaagc
    29761 ggcattgacc gggtcgttct gcccatcagc ctcgacccgg gagcggatcc cgatcgcgca
    29821 ggcagggttt ttttgccgtt actttaccca aaacaaaacg atcactcttt atgttgtggg
    29881 cgcaggcagg tggtaaccga cgtccgcacc aagggggatt cgcatgctgg ccatcaccag
    29941 ccgggaaggg cgcagcgcac cgggatccac atccgtcatc gaccccgtgc cacgcgaact
    30001 cgtccacaaa ctggccgaat ccgaggtcct gctgcgggga tgccggacgg tcgcgcccga
    30061 cacgttcctg atcaccgcac gctggcccgt cgaccactcc ttctacggcc ccgtccacgg
    30121 cctcttcgac ccgctgctcg cggcggaatc gatacgccag gcggtcccgc tgctcagcca
    30181 cgccgcctac gacgcgccgt tcgggcaccg gcagtcctgg gaccactacc ggcagacact
    30241 cttccccgcg gccctgacca gcggcacgac ggcggccgag acggaactgc gtatctcctg
    30301 caccgacgtg gtgcgccggg ccagccggct ggcctccctc accatgcggg tcgacatggt
    30361 ccgcggcggc ctgccgctcg gtaccgccga gctggccttc cacaaccacc ccccggccat
    30421 ctatcagcgg ctgcgcggcc cctacgccga cctggagcgg tccaccgcgc aagccgtggc
    30481 cgcgccgccg ccgatggcgc ccggtgaggt cgcccgcccg cggcccgccg acgtcgtgct
    30541 gtcggccacc gaggaccccg gccgcagccg gctgcgggtg gacctgtccc acccggtgct
    30601 cttcgaccac ccggtggacc acgtgcccgg aatgctgctg ctggaagccg cgcgacaggc
    30661 cgcgcaccgg gtggcgcatc ccgagccgat ggtggtgacc ggcctggaag ccgacttcaa
    30721 gcgcttcgtc gagctggaca cgccgtgctg gatcgagacc gcacgggaac cgtccggcgc
    30781 cgccggacag cgggtgcgcg tcaccgccgt gcagcgcgac gagaccctgt tcacgtccgt
    30841 cgtcacgctc acccccgcct ggtgaggacg gagacgtagc aggtcaggcc ggttgtagcc
    30901 gaaccgttgc cgtcccgtcg gaactccccc gcggcgaccg catagggtgt gatgccgttc
    30961 cgcaaggatg cggcccggca tgaactccgc ccaggtgaca tgccggtcgc acgtcctcat
    31021 cgccgagttc cttcacagca gggggagtca gaagcatgcg atccatacgg ccgtcgttca
    31081 ccgttctgcg agggaggggc ccgcaccgga ccgcccgcgc gttgacggcg gtcgccctcg
    31141 cctcggcact ggcgatgacc gccacggcct gcggcggcga caacgccgag ggcaagccca
    31201 ccgcgggcgc gaccgcgggc ggctccggcg acggcaagct caggatcccg gacgacctca
    31261 ggcagaggct caaggagcac gggatcgaca tcgacaagtg gaagaagggc gcctggaaga
    31321 actggaacaa gcaggactgg ctgcgcgagg ccgacgactt cgtcaacccc atgatcaagg
    31381 gcctgtggaa cccggaccgc atgcgggacg ccgacgaccc ggacaagggc gtcgacgaca
    31441 acgacatctc cggtgaccag ggcgtgacgg acccggcgcc gcagcccgtg cgggcgcgga
    31501 cggtcgttcc gccgtaccac agcaacgccg ccacctcggg caagctgctc ttcgacgccc
    31561 ccgagggcac gatggtctgt tcggcgacgg tcgtgacgga ccccgcgcac ccgggcaaat
    31621 ccaacctcgt ctggacggcg ggccactgtg tgcacgccgg caagaagggc ggctggtacc
    31681 gcaatctcgc cttcgtgccg tcgtacaaca accagggcag gtcggccgcc gagctggaga
    31741 acaccggccg ctccgaggtc gccccgtacg gcgtctggtg ggccgacgcg gcgaagacct
    31801 cgcagcagtg gatcagcgag ggcggtgcga cgggcggcaa cggcgcctcc tacgacttcg
    31861 ccgtcatcca cgtgaccccg gagcggggca gcggcggcga atcgctggag gagaccgtcg
    31921 gcggagcgct gccggtcgac ttcgacgcgc cggccgtgcc gaaggtgcag agcctcaccg
    31981 cgtccgggta tccggcggcg gcaccgtacg acggtcagct gctgtaccag tgccaggacc
    32041 atccgggccg gctgtccatg gaccggtccg acccgacgat gtaccggatc ggctgcacga
    32101 tgaccggtgg ctcctccggc ggcggctggg tggagacggg cgccgacggc aagccggcac
    32161 tggtgtccaa cacgtccatc ggccccggtg agttcgggct ggctggccgg cccccggctg
    32221 ggtgaggtgg ccaagggcgt gtacgactcg gtgagcaggc agttcgccgg ccggtaggcc
    32281 cctgtcctcg ggatcggacc ggatcgggtc gaccgctggc cggcccgagc ggggtccgcg
    32341 gggcccgcgc ccccggcgag atccgcggga agacaggccc tgaccgcgcc ctgtcgtgcc
    32401 ggaacaggcg aagaccccgc cgcccccgag ggggtggcgg gccttcgtga gccggtgctg
    32461 gatcagaccg tggtgaccgt gtacggcgcc aggtctgccg ccagctcctc gtgcacccgg
    32521 agcttgagca gggtgccctc cgcggtgtgc tcctcggaga tcacctcgcc ctcggtgtgg
    32581 gcgcgggcga ccagcttgcc gtgcgtgtag ggcacgaccg cctcgacctc gaccgagggg
    32641 cggggcagct cgtcgtcgat cagggcgagg agcttgtcga tgccctggcc ggtacgggcc
    32701 gagacggcga gggagcgctt ctcgacccgg agcagccgct ggaggaccag cgggtcggcc
    32761 gcgtccgcct tgttgatcac gacgatctcg gggacgccgg tggcaccgac gtcccggatc
    32821 acctcgcgca cggcggcgag ctgctcctcg gggttcgggt gcgagccgtc caccacgtgc
    32881 aggatcaggt cggagtcgcc gacctcctcc atggtggagc ggaacgcctc gaccaggtgg
    32941 tgcggcaggt gccggacgaa gccgacggtg tccgccaggg tgtacagccg gccgctcggg
    33001 gtctccgccc ggcggacggt cgggtccagg gtcgcgaaca gggcgttctc gaccaggaca
    33061 ccggcacccg tgaggcggtt gagcagggag gacttgccgg cgttggtata gcccgcgatc
    33121 gccacggacg gcaccttgtt gcgccggcgc tcctgccgct tgacctcgcg gccggtcttc
    33181 atgtccgcga tctcccggcg catcttcgcc atcttctcgc ggatccgccg ccggtccgtc
    33241 tcgatcttgg tctcaccggg gccacgcgtg gcgaggccgc cgcggccacc gcccatctgc
    33301 cgggacagcg actgacccca gccgcgcagc cgcggcagca tgtactgcat ctgcgcgagc
    33361 gcgacctgcg ccttgccctc acgggacttg gcgtgctggg cgaagatgtc caggatcagg
    33421 gccgtacggt cgatgacctt gaccttgacg acgtcctcaa gctggatcag ctggccgggg
    33481 ctcagctcac cgtcgcagat gacggtgtcc gcgcccgtct ccaggacgac gtcgcgcagc
    33541 tccagggcct tgccggagcc gatataggtg gccgcgtcag gcttgtcacg gcgctggatg
    33601 acaccgtcga gcacgatcgc gcccgcggtc tcggcgaggg cggccagctc cgcgagggag
    33661 ttgtcggcgt cctgcgcggt gccggtggtc cacacgccga cgagcacgac ccgctccaga
    33721 cggagctggc ggtactcgac ctcggtgacg tcctccagct cggtggacag gcccgccaca
    33781 cggcgcaggg ccgcacgctc ggagcggtcc aactggtcgc cgtcccgctc gccgtcgctc
    33841 tcgaagctcc aggcgacgtc ctcttccatc agggcatcgg cccgaagacc ttcggggtag
    33901 gcgtgcgcga ggcgcttggt gtcctgggaa ggggaagaag aggaggtcat ttgatccttt
    33961 acgtcgatga gagtgccgtt acggcgtcgg tacggcggtc tgctcggccg ctcgtgctgt
    34021 acaacgcacg ggtaccccgg gagattccct tgtccccccg tgcgggccgc cgcctagatg
    34081 gtcgcacggt acggcacgtc tcgtcatcgg cttatcgcct ggcgcgcggc tcggcgggcc
    34141 cggtcttggc cgtcggcctc cagtcggggt ggccgggcat cggcggggtc ttctcgccgt
    34201 acagccaggc atcgaggaac ccccgcaggt cgcggccggc gacggccgag gccagccgga
    34261 cgaagtcggc ggtggtggcg gtggcgtccc ggtgttcctg gacccacagc cgctccagcc
    34321 gctcgaaggc cggccggccg atctcctgcc gcagcgcgta gagcgcgagt gcggcgccgt
    34381 cgtagacgct gggccggaag atgccgatct tctggccggg ggcgggcggc ttgggccggg
    34441 cgggcgggcc gccggactcg cgccagcggt cggcggcgcc gtaggcggcc ttcatccggt
    34501 ccttcatggg ccggtgcgcc gtctcctcgg cgtacagctc ctcgtaccag gtggcgtgcc
    34561 cctcgttcag ccacacgtcg gaccaggtgc gcggggtgac gctgtcgccg aaccactggt
    34621 gggacagctc gtgcaccatc accgactcga tgtaccactc ggggtaggcg ggcttggtga
    34681 acaggtcctt ctcgaacagt gacagggtct gtgtctccag ttcgaagccg gtggcggcct
    34741 gtgccatgag tacgccgtag gtctcgaacg ggtagcggcc gaccttgctc tccatccagg
    34801 cgatctggtc gggcgtcctg gcgagccagg gctcgagggc cttgtggtcg gcggcgggca
    34861 cgacgtcccg caggggcagc ccgtgcggtc ccgcgcggtg caccacggcg gagcggccga
    34921 tggacacctg ggcgagttcg gtggccatgg ggtgcagggt gcggtaggtc caggtggtgg
    34981 tgcggccgac ccggtacgcg ccggtgggca ggccgttggc gacggcggtg cagccgtcgg
    35041 gggcggtgat ccggaaggtg aacatcgcct tgtcggacgg gtggtcgttg cccgggaaga
    35101 ccaggtgggc ggcgtcggcc tggttggcca tggcgaggcc gtccacggtg cgcacccagc
    35161 cgccgtcctg gtccttggcg ggggcggggt cgctggtgtg ccgcacggtg atccgggtcc
    35221 ggctgccctc ggtcaggggg gtccgcggtg tcacgaccag gtcctcgccg gcactggtga
    35281 agcgggcggg acgcccgtcg acctcgaccg accgcacggt gccgtgggcg aagtcgaggt
    35341 tgacgcggtc caggtcggcg gtggtccggg cgtcgatggt ggtgacggcc tggagcggct
    35401 tgtcgttggt gcccgcgtag gtgagggaga tgtcgtacga ggccacgtcg tagcccgggt
    35461 tgcccaggta cgggtagagg cggtcgccga cgcccagggg ctcgggcggg gccgcggcgg
    35521 cgacgaggca gacggagacg gcgcaggcga gcagggccgc cttgcggtgt cgggagatcc
    35581 ggggccggga ccggtggcgc ggggtgagca gcatggacca ccgctaccag ggcgggcccg
    35641 cgccgcggcg gcgactcgcg cccggcccac ccgaacgggt cggccgcggg acgccgtcct
    35701 caggaggccg gtgcctggtg ctgggcgcgg ctgacgtcgt acacgcccgg tacgtcccgc
    35761 atggcgcgca tcagggccgg gaggcgggca gcgtcgggca gctcgagggt gtaggtgtgg
    35821 cgaacccgct gctgggtggg gggttccacg gtggcggaga cgatc
//
