LOCUS       NZ_CP033073            26687 bp    DNA     linear   CON 23-OCT-2024
DEFINITION  Streptomyces dangxiongensis strain Z022 chromosome, complete genome.
ACCESSION   NZ_CP033073
VERSION     NZ_CP033073.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces dangxiongensis
  ORGANISM  Streptomyces dangxiongensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     The genome of Streptomyces dangxiongensis Z022
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8085191)
  AUTHORS   Zhang,B.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) State Key Laboratory of Cryospheric
            Sciences, Chinese Academy of Sciences, Donggang West Road 320,
            Lanzhou, Gansu 730000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: FALCON v. version 0.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 213.0x
            Sequencing Technology             :: Illumina and Pacpio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003675325.1-RS_2024_10_23
            Annotation Date                   :: 10/23/2024 04:16:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,241
            CDSs (total)                      :: 7,151
            Genes (coding)                    :: 6,614
            CDSs (with protein)               :: 6,614
            Genes (RNA)                       :: 90
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 537
            CDSs (without protein)            :: 537
            Pseudo Genes (ambiguous residues) :: 0 of 537
            Pseudo Genes (frameshifted)       :: 320 of 537
            Pseudo Genes (incomplete)         :: 281 of 537
            Pseudo Genes (internal stop)      :: 26 of 537
            Pseudo Genes (multiple problems)  :: 83 of 537
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 02:47:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1165662
            Orig. end                         :: 1192349
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033073.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Binglin Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26687
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="10"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26687
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26687
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16687](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16687)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    611..623
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    656..670
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.63"
                     /tool="antismash"
     misc_feature    complement(686..701)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    complement(744..762)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     gene            complement(901..1815)
                     /locus_tag="D9753_RS05065"
                     /old_locus_tag="D9753_05065"
     CDS             complement(901..1815)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386177.1"
                     /locus_tag="D9753_RS05065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05065"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_121785910.1"
                     /transl_table=11
                     /translation="MPAKGKHRRPKPQRFSRSLAAAGTGGAALALPLIGATGAHAAQAA
                     APEHAVSGKTVQSLPDTADKTAARSGPELRTYTVRSGDYLSKIAGEQRVSGGWQRLYDD
                     NRQAVGADPSLIHPGLKLSLGGKAAQTRTESATPRHAPAAPNSTRSAPARQSAPASESA
                     STPTSAGYTLPVAGAVTGTGYRVAGGMWSSGYHTGVDFVVPTGTPLKAVAAGTVVSAGW
                     GGAYGNQVVIRLNDGYYAQYGHLSHLSVSAGQSVTPGQPIGLSGATGNVTGPHLHFEIR
                     TTPAYGSDIDPVGYLRRHGLAVG"
     misc_feature    1799..1814
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.08"
                     /tool="antismash"
     regulatory      complement(1819..1976)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    2108..2121
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.08"
                     /tool="antismash"
     misc_feature    complement(2116..2127)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     misc_feature    complement(2247..2263)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            complement(<2300..2603)
                     /locus_tag="D9753_RS37640"
                     /old_locus_tag="D9753_05070"
                     /pseudo=""
     CDS             complement(<2300..2603)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116609.1"
                     /locus_tag="D9753_RS37640"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="D9753_05070"
                     /product="alpha-galactosidase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MADIAEDGRTWLLSGPRSSYAPHLTDAGELLRLHWGRGSSPPTPK
                     PSRSTRCPSTGPSSPRSTAGRSIPSRRPPLRPPRPVRAHRRAARHRVAFRGVRHFR"
     misc_feature    2699..2710
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.78"
                     /tool="antismash"
     gene            2773..3570
                     /locus_tag="D9753_RS05075"
                     /old_locus_tag="D9753_05075"
     CDS             2773..3570
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="D9753_RS05075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05075"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_163010627.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLPTTDGRRVRYGVLFRSGHLAH
                     ATEDDAAFLASLGLHTVFDFRNTADQRLEGPDVELPGVRNVNLPLSDPADGAEFWTMVR
                     DGDLDQLRAILDDGKGAARMIASYRKIVRERTAEHSRVLHALADDSVPALMHCAAGKDR
                     AGISIAVTLLALGVERDAVVADYLESNATHRRYKVRRSGSADSAYTPEVMELLDPLFDA
                     RAEYLEAAFESIEETWGDVDTYLRQGLDLSPGTRERLRERLLD"
     gene            complement(3607..3729)
                     /locus_tag="D9753_RS05080"
                     /old_locus_tag="D9753_05080"
     CDS             complement(3607..3729)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676213.1"
                     /locus_tag="D9753_RS05080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05080"
                     /product="DUF6126 family protein"
                     /protein_id="WP_121785912.1"
                     /transl_table=11
                     /translation="MSDFETKFPRSLWIRLIIYIALGHVLAAFLYLLFTVGAKS"
     gene            complement(3726..4349)
                     /locus_tag="D9753_RS05085"
                     /old_locus_tag="D9753_05085"
     CDS             complement(3726..4349)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676212.1"
                     /locus_tag="D9753_RS05085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05085"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_121785913.1"
                     /transl_table=11
                     /translation="MNASDVPPPTGPGDDLPAVAPQLRALRRRAGLTLEAAARAAGLSP
                     AHLSRLETGHRQPSLPMLLALARIYGTTVSELLGETVADRDAIVRAADMEPTRAGGWTY
                     TQAGASGRGMQALRVRVPHGSQGDIVRVHPGEEWLYVLRGRLRLRLGDTAHLLAPGDSA
                     HFDSLTPHRLAAEDQDGVELLFVHTLLQSPTATLCLGPLTGELP"
     misc_feature    4379..4395
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.91"
                     /tool="antismash"
     misc_feature    complement(4558..4573)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.68"
                     /tool="antismash"
     misc_feature    complement(4559..4568)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            4578..4865
                     /locus_tag="D9753_RS05090"
                     /old_locus_tag="D9753_05090"
     CDS             4578..4865
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D9753_RS05090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D9753_05090"
                     /product="hypothetical protein"
                     /protein_id="WP_121785914.1"
                     /transl_table=11
                     /translation="MSASTTPGRADAPAVGLGPTALVLGTVAAAGVWPTLTFALLPVMP
                     IAGGLAVTFGLMGVHQARQGVGRLWTAVTGTALGAVGFLYLFVLLMALSG"
     gene            complement(4890..6275)
                     /locus_tag="D9753_RS05095"
                     /old_locus_tag="D9753_05095"
     CDS             complement(4890..6275)
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 2.1e-86.
                     Score: 281.9. Matches aSDomain:
                     nrpspksdomains_D9753_RS05095_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494124.1"
                     /locus_tag="D9753_RS05095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05095"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_121785915.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.6e-84, bitscore:
                     281.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEFDLGALLAQRGAERYELHAKHLNPQLPRMLHTIGFDKVYER
                     AEGAHFYDDEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVLDMDLADLTRFDCQPLPGL
                     LAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGRPRILYCDHAFHGLTTGSLSVN
                     GENGFRDGFDPLLPDTAVPLGDLDALARELSKGDVAGLIVEPIQGKGVHPTPPGYLRAA
                     QGLLRRYRALLIVDEVQTGLGRTGDFYAYQHEDGVEPDLVCVAKALSGGYVPVGATLGK
                     EWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENEQIVAGVRRTGELLKSRLT
                     ALIDRYELLADVRGRGLMIGIEFGRPSSLALRSRWTVLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLIVDEADVDRFVDAFTAVMDDAHNGSGLLWDFGKTLIKQAV
                     ANR"
     aSDomain        complement(5187..6152)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D9753_RS05095_Aminotran_3.1"
                     /evalue="2.10E-86"
                     /label="D9753_RS05095_Aminotran_3.1"
                     /locus_tag="D9753_RS05095"
                     /protein_end="363"
                     /protein_start="41"
                     /score="281.9"
                     /tool="antismash"
                     /translation="VYERAEGAHFYDDEGNDYLDMLAGFGVMGLGRHHPVVRRALHDVL
                     DMDLADLTRFDCQPLPGLLAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGRPRI
                     LYCDHAFHGLTTGSLSVNGENGFRDGFDPLLPDTAVPLGDLDALARELSKGDVAGLIVE
                     PIQGKGVHPTPPGYLRAAQGLLRRYRALLIVDEVQTGLGRTGDFYAYQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGKEWIFRKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMENE
                     QIVAGVRRTGELLKSRLTALIDRYELLADVRGRGLMIGIEF"
     gene            complement(6272..8170)
                     /gene="dxs"
                     /locus_tag="D9753_RS05100"
                     /old_locus_tag="D9753_05100"
     CDS             complement(6272..8170)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676210.1"
                     /locus_tag="D9753_RS05100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05100"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_121785916.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3.9e-111,
                     bitscore: 369.3, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.7e-06, bitscore:
                     25.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILESIRGPHDLKALSEARLGELTDEIREFLVHAVSRTGGHLGP
                     NLGVVELSVALHRVFDSPADRILWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSRAE
                     SEHDVIENSHASTALGWADGLAKARQVRGEKGHVVAVIGDGALTGGMAWEALNNIAAAR
                     NRPLIIVVNDNERSYAPTIGGLARHLATLRTTDGYEKVLAWGKDVLQRTPVVGNTLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYVGPVDGHDIGAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALAHEEDHFHTVGVMDPLTCAPLVPSRGPSWTSVFGDEIVRIGEEREDVVAVT
                     AAMLHPVGLGEFAERFPDRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGVDGASHNGMWDMSVLQVVPGLRIAAPRDPDQLRAQL
                     REAVAVDDAPTLVRFPKESAGPPVPALDRVGGMDVLHRAAHPDVLLVAVGVMAPVCLQA
                     AELLEARGLGCTVVDPRWVKPVDPALPGLAAGHRTVAVVEDNSRAAGVGSAVALALGDA
                     DVDVPVRRFGIPEQFLAHARRDEVLADIGLTPVEIAGRISAALAVKDAGGTAKESQ"
     gene            complement(8330..9352)
                     /gene="hpnH"
                     /locus_tag="D9753_RS05105"
                     /old_locus_tag="D9753_05105"
     CDS             complement(8330..9352)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="D9753_RS05105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05105"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_121785917.1"
                     /sec_met_domain="PF04055 (E-value: 5.7e-18, bitscore: 64.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.4e-08, bitscore: 32.4,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLAEQKLRKRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVARKKYVF
                     LCTNAMLLRKKIDNFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEARRRGF
                     RVTTNSTFFNTDTPQTIIEVLNFLNDDLQVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FRKAFAGGNRRKWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEKTDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAMRETVSGNRD
                     "
     gene            complement(9358..9999)
                     /locus_tag="D9753_RS05110"
                     /old_locus_tag="D9753_05110"
     CDS             complement(9358..9999)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848330.1"
                     /locus_tag="D9753_RS05110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05110"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_121785918.1"
                     /transl_table=11
                     /translation="MRAAPVAAPLLIACALGIEHLALRTGDRSGADGPVTVVRTGMGPR
                     AAERSVTRHLGGPALAGAAVLATGFCAGLAPGMHPGDLVVAEETRDPRGTVPCAGTAAL
                     VEELVRRLPGRTVHTGPLTGSDHVVRGHERSDLLATGAIAVDMESAATLLAAVRAGPRP
                     TAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSVLPALFEWHRSLPLPRR"
     gene            complement(10001..12034)
                     /gene="shc"
                     /locus_tag="D9753_RS05115"
                     /old_locus_tag="D9753_05115"
                     /pseudo=""
     CDS             complement(10001..12034)
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676206.1"
                     /locus_tag="D9753_RS05115"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05115"
                     /product="squalene--hopene cyclase"
                     /pseudo=""
                     /sec_met_domain="T2TS (E-value: 3.1e-46, bitscore: 156.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGATLPSRAAAASDTTFTIPEAAGVREAAARAAQRAT
                     DSLLSRQDVQGWWKGDLETNVTMDAEDLLLRQFLDILDESTTQAAARFIRGEQRDDGTW
                     ATFYGGPGDLSATVEAYVALRLAGDAPDAPHMAKASAWVRERGGIAAARVFTRIWLALF
                     GWWRWEDLPELPPELIWFPTWMPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDEL
                     CTPTPPAPFRPSPAPR"
     gene            complement(12147..13280)
                     /locus_tag="D9753_RS05120"
                     /old_locus_tag="D9753_05120"
     CDS             complement(12147..13280)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058832.1"
                     /locus_tag="D9753_RS05120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05120"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_121785919.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.7e-58, bitscore:
                     195.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDQQAAGPRTPGTATRGETVPTVPPASTPAPRAAVDVTALLERG
                     RTLATPVLRAAVDRLAPPMDTVAAYHFGWIDAAGNPADGDGGKAVRPALAVLSAEVTGA
                     APEAGIPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALAN
                     EVLLELGTVEAGRATRRLTTATRALIDGQAQDISYEHRDRVSVEECLEMEGNKTGALLA
                     CASSIGAVLGGADDATADALERYGYHLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRK
                     KSLPVVAALAAGGPASEQLGEILAADAKSSDFENFSEEEFAARAALIEEAGGREWTARE
                     ARRQHTIAVEALDAVDMPDRVRDSFTALADFVVVRKR"
     gene            complement(13280..14707)
                     /gene="hpnE"
                     /locus_tag="D9753_RS05125"
                     /old_locus_tag="D9753_05125"
     CDS             complement(13280..14707)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004980264.1"
                     /locus_tag="D9753_RS05125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05125"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_121785920.1"
                     /sec_met_domain="DAO (E-value: 1e-06, bitscore: 27.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDGSRPAPAHAATPQPAGRSAVVVGGGLAGITAALALADAGVRV
                     TLLEGRPRLGGLAFSFRRGELTVDNGQHVYLRCCTAYRWFLDRIGGAALAPLQDRLDVP
                     VVDVTKPAGRRLGRLRRDPLPVPLHLGRSLAAYPHLSLAERAAVGRAALALKGLDLADP
                     ALDTQDFGSWLAAHGQSARAVEALWDLVGVATLNAVAGDVSLGLAAMVFKTGLLSDPGA
                     ADIGWARVPLGELHDRLARRALDSAGVRTQVRARVTSLSLHANGSWSVQLPGETLETDA
                     VVLAVPQREAHELLPSGALDAPQRLLEIGTAPILNVHVVYDRRVLAGPFFAALGTPVQW
                     VFDRTDASGLRTGQYLALSQSAAQDEIDTPVAELRERYLPELARLIPGARTAVVEDFFV
                     TRERTATFAPTPGVGRLRPGARTKATGLYLAGAWTATGWPATMESAVRSGVSAADAALG
                     ALGRPRPRRLFGFEEAA"
     gene            complement(14704..14832)
                     /locus_tag="D9753_RS39260"
     CDS             complement(14704..14832)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039420.4"
                     /locus_tag="D9753_RS39260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6380 family protein"
                     /protein_id="WP_394346687.1"
                     /transl_table=11
                     /translation="MDLPGPDGSGRATPRSGVASLTATAGRAPFDQHVRHARKDAR"
     gene            complement(14832..15794)
                     /gene="hpnD"
                     /locus_tag="D9753_RS05130"
                     /old_locus_tag="D9753_05130"
     CDS             complement(14832..15794)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494139.1"
                     /locus_tag="D9753_RS05130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05130"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_163010628.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.5e-56, bitscore:
                     190.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 7.3e-70,
                     bitscore: 234.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTVDSPPHVSAPVLAAYSYCEAVTGQQARNFAYGIRLLPTAKR
                     RAMSALYAFSRRVDDIGDGDLAREVRPARLEDTRTLLARVRDGKVEEDDTDPVAVALAH
                     AAQAFPIPLGGLDELIDGVRMDVRGQTYETWDDLKVYCRCVAGAIGRLSLGVFGTEPGA
                     RGAERAPEYADTLGLALQLTNILRDVREDAEDGRTYLPADDLAKFGCSDGFQGPTPPDG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGHEKAYVAVRGLSGLDTRHVTRHVSRRSVRRRA"
     gene            complement(15791..16687)
                     /gene="hpnC"
                     /locus_tag="D9753_RS05135"
                     /old_locus_tag="D9753_05135"
     CDS             complement(15791..16687)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985319.1"
                     /locus_tag="D9753_RS05135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05135"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_121785921.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.9e-40, bitscore:
                     137.5, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.2e-41,
                     bitscore: 140.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATDPAPDLERATLDKAASENFPVAPFFLPRAWREDLMAVYGFA
                     RLVDDIGDGDLAPGGGDARLLGVSPDAAEDRPALLDAFETDLRRVFDGTPRHPLLRRLQ
                     PTVRRHALTPEPFLALIAANRQDQLVTRYETYDDLLAYCELSANPVGRLVLAVTGTSTP
                     ERIRLSDAICTALQIVEHLQDVAEDLGRDRIYLPAQDMKRFHVRETDLAARTAGASVRA
                     LVAYEAQRARDLLNEGAPLVGSVHGRLKLLLAGFVAGGRAAIRAIAAAGFDVLPGPPEP
                     GTFQLLREAGVILRGEG"
     gene            complement(17047..17835)
                     /locus_tag="D9753_RS05140"
                     /old_locus_tag="D9753_05140"
     CDS             complement(17047..17835)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004922385.1"
                     /locus_tag="D9753_RS05140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05140"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_121785922.1"
                     /transl_table=11
                     /translation="MAEHDNDERRPTVIADELHIVYRVNGARTGKGSATAALSRILRRG
                     SDDTARGVRKVHAVRGVSFVAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGKVYTDG
                     QPSLLGVNAALMNDLTGERNVILGGLAMGMSREQVKERYQDIVDFSGINEKGDFITLPM
                     RTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEERIRELRKEAGTVFLVS
                     HNNKSIRDTCNRVLWLERGELRMDGPTDEVLKEYEKFTGK"
     gene            complement(17828..18757)
                     /locus_tag="D9753_RS05145"
                     /old_locus_tag="D9753_05145"
     CDS             complement(17828..18757)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="D9753_RS05145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05145"
                     /product="ABC transporter permease"
                     /protein_id="WP_121785923.1"
                     /transl_table=11
                     /translation="MSETTHDGTVAVTAAPSPDEGVTADQLAARYGLTVSGARPSLVEY
                     VRQLWGRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNAAVYFFIFGLILHASRGMS
                     RDVYIPFLVTGVFVFTFTQSSVMSGVRAISGNLGLVRALHFPRASLPVSFSLQQLQQLL
                     FSMIVLFVVAIGFGSYPSPSWLLILPVLVLQFLFNTGLAMIVARMGAKTPDLAQLMPFL
                     LRTWMYTSGVMFSINKMLEGRPEWIVRLLQVNPAAIYMDLMRFALIDGYGASNLPPHVW
                     VIALFWAVAVFAGGFVYFWKAEERYGRG"
     misc_feature    18752..18767
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.21"
                     /tool="antismash"
     gene            complement(18847..19719)
                     /locus_tag="D9753_RS05150"
                     /old_locus_tag="D9753_05150"
     CDS             complement(18847..19719)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="D9753_RS05150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05150"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_121790910.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.1e-13,
                     bitscore: 47.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVVITMGNRPEELRALLDSVAKQDGDPVEVVVVGNGSPVPD
                     VPAGVRTIELPENLGIPGGRNVGIEAFGPSGRDVDILLFLDDDGLLARHDTAELCREAF
                     AADPALGIISFRIADPGTGETQRRHVPRLRAADPMRSSRVTTFLGGANAVRTRVFAEVG
                     GLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLYHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPALLVPVYLGVWLLLTLLRRPSRPALKAWFGGFREGWATPCGPRRPMRWRTVWRL
                     TRLGRPPVI"
     gene            complement(19725..20510)
                     /locus_tag="D9753_RS05155"
                     /old_locus_tag="D9753_05155"
     CDS             complement(19725..20510)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="D9753_RS05155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05155"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_121785924.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRVDRYLV
                     NTRVTPNQLTYLMTVCGVLAAPALLVPGIAGAVLGIVATQLYLLLDCVDGEIARWKKQY
                     SLGGVYLDRVGAYLTDAAVLVGLGLRAADLWGSGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQAGMPPVQDAAGVAEPRSAGMALARRAASALRFHRLILGIEASLLILVLAIA
                     DQARGDLFFTRLGTAVLAGIAVLQTLLHLVSVLASSRLR"
     gene            complement(20488..21549)
                     /locus_tag="D9753_RS05160"
                     /old_locus_tag="D9753_05160"
     CDS             complement(20488..21549)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="D9753_RS05160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05160"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_121785925.1"
                     /sec_met_domain="Fe-ADH (E-value: 3.2e-20, bitscore: 71.0,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRPGALDDLAGVLADERISQSGRLAIAVSG
                     GSGARLRDRIAPSLPGATWYEVDGGTIDDAVRLAGDIKAGHYDAVVGLGGGKIIDCAKF
                     AAARVGLPLVAVATNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLNVIREAPVRF
                     VRSGIGDAISNISAVADWELSHRVNGEKIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEALVLTGIAMSVSGDSRPSSGACHEINHAFDLLHPKRAAAHGEQCGLGAAFAMYLRG
                     AHEEAAYMAGVLRRHGLPVLPEEIGFTVDEFVRVVEFAPETRPGRYTIIEHLDLKTNQI
                     KDIYADYVKAIGS"
     gene            complement(21537..22289)
                     /locus_tag="D9753_RS05165"
                     /old_locus_tag="D9753_05165"
     CDS             complement(21537..22289)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="D9753_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05165"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_121785926.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 4.6e-10, bitscore:
                     38.7, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDSLPKALVPVGPAGIEGEPTVLDLTLG
                     NFAEIGLTEVAIIVGYRKEAVYERKAALEQKYGLKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVERTLLAARGEGRRIILALDTVKSLADEEMKVVVDPAKGVRK
                     ITKLMDPAEATGEYIGVTLIEGDAAPELADALKAVWESDPQQFYEHGYQELVNRGFRID
                     VAPIGDVPWVEIDNHDDLARGREIACQY"
     gene            complement(22286..24133)
                     /locus_tag="D9753_RS05170"
                     /old_locus_tag="D9753_05170"
     CDS             complement(22286..24133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="D9753_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05170"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_121785927.1"
                     /transl_table=11
                     /translation="MSTAIVTGQPVPGSSLENDLRSLGFDVRVAADAAEAEALLAAVPA
                     DRRVALVDSRFVGHPHALRLGLTDPRFPLAAVPGAVTAQPAARQALTRAVARETSAGTG
                     TAGEPAPLAPGGAPALAPDSLADHVVTALDAEGGAVHRPELGSLVATVPADPQARNEAR
                     QAVAAVDDEAVRLKSAVKARDGFFTTFFISPYSRYLARWCARRGLTPNQVTTASLLTAL
                     IAAGCAATGTRGGFVAAGVLLIASFVLDCTDGQLARYALKYSTLGAWLDATFDRAKEYA
                     YYAGLALGAARGGDDVWALALGAMILQTCRHVVDFSFNEANHDATANTSPTAALSDKLD
                     SVGWTVWLRRMIVLPIGERWAMIAVLTAVTTPRITFYVLLVGCAFAATYTTAGRVLRSV
                     TRRARRTDRAAQALADLTDSGPLAEAVGRVAGRGLPGLAVPAVALLGGAAVVACSALTG
                     FGGVVPVAGALVYVLTSALAVARPLKGALDWLVPPFFRAAEYGTVLALAGKAGVNGALP
                     AAFGLVAAVAYHHYDTVYRIRGDAGAPPAWLVRAVGGQEGRTLLVTVLAAVLTASQFKA
                     ALTVLAVAVALLVLVESIRFWVSAHKGGAPAVHDEGEPA"
     gene            24399..25370
                     /gene="galE"
                     /locus_tag="D9753_RS05175"
                     /old_locus_tag="D9753_05175"
     CDS             24399..25370
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (66-183). E-value:
                     3.9e-11. Score: 34.5. Matches aSDomain:
                     nrpspksdomains_D9753_RS05175_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676194.1"
                     /locus_tag="D9753_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05175"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_121785928.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.2e-18, bitscore:
                     63.0, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.9e-10,
                     bitscore: 38.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMTGAGESVVALDDLSAAVPARLPAEV
                     PLVRGSTLDGALLKRVLTEYGVTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLDAV
                     AEAGVGRLLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGIST
                     VCLRYFNVAGAAAPELADTGVFNIVPMVLDRLTRDEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLAEAHLAAARRLADGDAAGDLTLNIGRGEGVSVRELITVIGEVTGDRRAPVVEGRRP
                     GDAPRAVASAERAAEALGWRARRGVREMAESAWQGWRLHHGG"
     CDS_motif       24402..24470
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_D9753_RS05175_0001"
                     /evalue="4.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="D9753_RS05175"
                     /protein_end="24"
                     /protein_start="1"
                     /score="16.1"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMTGAG"
     aSDomain        24597..24947
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D9753_RS05175_NAD_binding_4.1"
                     /evalue="3.90E-11"
                     /label="D9753_RS05175_NAD_binding_4.1"
                     /locus_tag="D9753_RS05175"
                     /protein_end="183"
                     /protein_start="66"
                     /score="34.5"
                     /tool="antismash"
                     /translation="VTGVVHLAARKQVAESVAQPTRYYRENVGGLATLLDAVAEAGVGR
                     LLFSSSAAVYGNPDVDLITEDTPCAPVNPYGETKLAGEWLVRAAGRAHGISTVCLRYFN
                     VAGAAAPELADTG"
     misc_feature    complement(25443..25457)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25529..26470
                     /locus_tag="D9753_RS05180"
                     /old_locus_tag="D9753_05180"
     CDS             25529..26470
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009339288.1"
                     /locus_tag="D9753_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9753_05180"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_121785929.1"
                     /transl_table=11
                     /translation="MGAGHDHGHGHSHVPATGTATAAYRGRLRIALGITLTVMLVEIAG
                     GLLADSLALIADAAHMATDAVGLGMALLAVHFAGRPPSTNRTFGLARAEILAALANCLL
                     LLGVGGYVVYEAVQRFVEPADTRAGLMIVFGLVGLVANSVSLVLLMRGQKESLNVRGAF
                     LEVAADALGSVAVLISATVILTTGWQPADPVASLVIGLMIVPRTVRLLRETLDVLLEAA
                     PKDVDMAEVRAHILALDGVEDVHDLHAWTITSGMPVLSAHVVVSSEVLNAIGNEKMLHE
                     LQGCLGDHFDVEHCTFQLEPGGHAEHEARLCH"
     misc_feature    complement(26475..26490)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.31"
                     /tool="antismash"
ORIGIN
        1 gtcgcggcgg atgtccaggg tgccccgggg cggcagcggc ggccacggct gctctgggtc
       61 ggccgggacg tccaggccga ggacctgccc ggcccgcagc gccacgcgcg tgtgcccctc
      121 gggcgagagg tgcagccggt cgcggtccca ggccctgcgg tcctgcacgg acctgaggga
      181 ccacaggtcg agcacggggc agccgtaccg gtcggcgatg gcgcggacgt gtccgttgta
      241 cgtggctatc ttgccgcgca ggtgcttgag cacgggcacg ccgcgggtgt cgaaaccggt
      301 cgtcaccagc accgtgccga cggcctcggt cagccgggcc acggcgcgtt cgaagcgctc
      361 ggccacctcg tccgggtcgg tgcccgggcg gatgatgtcg ttgccgcccg cgcagaagga
      421 gaccaggtcc ggggccagtt cgacggccct ggggagctgg accgccatga cctggtccag
      481 cagtttgccg cgcacggcga gattggtgta ctggaagtcg ccctcgggac gccggtcggc
      541 gagcagtacc gcgaaccggt cggcccagcc cacgaacgct ccgtcggggc cggggtcgcc
      601 gacgccctcg gtgaagctgt cccccaccgc cacgtacgac ccgatcactg atctgttgtc
      661 attcttcgaa tcgtcttcca cgtcggacca tgattcacct tcggatgtga cctacgcgac
      721 cgtaagcggg ggttgacgaa cggtgagatg agccactcct aaagaatccg ccaaccacgg
      781 aatagggccg ccgtcaggtg cgttgaacgc cccgcaaccg gaacgtcgaa ggccgggccc
      841 ctggatcggg gtccggcctt cggcggcgtg tcgggcgggt ggtgcgggag gggcgcggtg
      901 tcagcccacg gcgaggccgt gccggcggag gtagccgacc gggtcgatgt cggagccgta
      961 ggccggcgtg gtgcggatct cgaagtgcag gtgcgggccg gtcacgttgc cggtggcgcc
     1021 ggacaggcct atcggctggc ccggggtgac gctctggccg gccgagacgg agaggtgcga
     1081 gaggtggccg tactgggcgt agtagccgtc gttcagccgg atgacgacct ggttgccgta
     1141 cgcgccgccc cagccggcgg agacgacggt gcccgcggcg acggccttca ggggcgtgcc
     1201 ggtcgggacg acgaagtcga ctccggtgtg gtagccgctg gaccacatgc cgccggccac
     1261 gcggtagccg gtgccggtga ccgcgccggc caccgggagg gtgtaaccgg cggaggtggg
     1321 cgtggaggcg gattcggagg ccggggcgga ctgcctggcc ggggcggacc gggtggagtt
     1381 cggggctgcc ggggcgtgcc gcggggtcgc ggactcggtg cgggtctgcg cggcctttcc
     1441 gccgaggctg agcttcaggc ccgggtggat cagcgacgga tcggcgccga cggcctgccg
     1501 gttgtcgtcg tagagccgct gccagccgcc gctgacacgc tgctcgccgg cgatcttcga
     1561 gaggtagtca ccgctgcgga ccgtgtaggt gcgcagctcc gggccggacc gcgcggcggt
     1621 cttgtccgcc gtgtccggga gggactgcac ggtcttgccg gacacggcat gctcgggggc
     1681 cgcggcctgc gcggcgtgtg cgccggtggc cccgatcagc gggagggcca gtgcggcacc
     1741 gccggttccg gcggcggcga gggaacggga gaaacgctgg ggcttggggc gtcggtgctt
     1801 acccttggcg ggcataactc ggttcctctc cggcgcctgc gaggtcagct gtcgggttcg
     1861 ggctggagct gcccggccgt gtgctgcacg gctgcacccc atagcctgtc gcggagaccg
     1921 ggacaggcag tcgtacctgg tgggtccccc gctcctgccg gacgcgggtc aagtgtgggg
     1981 ctccgggcgg cggcaggatt cggcgttccg tccggattgg tggtgaacgt aagcgagcgg
     2041 gacgtgagga aacaagcacc tggttcccgc tgttcgtgtt tcgggtgacg ggatacggga
     2101 actcatcgtc accctgcgtg catttccctc tcccccgtcc ctcgaaattc ccccgccctt
     2161 agcgctatta cgtggacatg ccacgcgacg cacggtcacg gatatgacgc tgatcacgcg
     2221 aggccttccc atatccaccc cttccgctgc gagttgtgca cagagtcgca attcgggcac
     2281 acgactcaga cgcgacgcgg ccggaagtgt cgtacgccac ggaacgccac tcggtgccgc
     2341 gccgctcgtc ggtgcgcacg gacagggcgg ggcggacgga gcgggggccg cctcgacggg
     2401 atgctcctcc cggccgtcga gcggggactc gaagggccgg tggacggaca gcgggtcgac
     2461 cgcgagggct tcggcgtcgg cggggacgat ccgcggcccc agtgcagacg gagcagttcg
     2521 ccggcgtcgg tgaggtgcgg ggcgtaactg ctgcgggggc ccgacaggag ccacgtacga
     2581 ccgtcttcgg cgatgtccgc catcgagacc tcacagatgt cacggtcccg ctcagacacc
     2641 gacatcatcg agggcgccgg acggcgtgac catgcctgtg gacaactggt cgcctgggga
     2701 aatcgatgtc gtatggtcgt cggagtgccc gccggtgagc cgcgccggcg gggccgaccg
     2761 ggaggagccc ccgtgacgca gcaggtcccg tcgaccgagc cggagctggc cggagtgcgc
     2821 aatttccgtg acgtgggcgg gctgcccacc acggacggac ggcgggtgcg ctacggcgtg
     2881 ctgttccgca gcgggcatct ggcgcacgcg accgaggacg acgcggcgtt cctcgcctcc
     2941 ctgggcctgc acacggtgtt cgacttccgc aacacggcgg accagcggct ggagggcccc
     3001 gacgtcgagc tgcccggcgt gcggaacgtg aacctgccgc tgagcgaccc ggcggacggc
     3061 gccgagttct ggacgatggt ccgggacggc gacctcgacc agctccgcgc gatcctggac
     3121 gacggcaagg gagcggcccg gatgatcgcc tcctaccgga agatcgtcag ggagcgcacc
     3181 gccgagcact cccgggtact gcacgcgctc gccgacgaca gcgtgcccgc gttgatgcac
     3241 tgtgcggccg gcaaggaccg cgcgggcatc tccatagcgg tgacactcct cgccctgggg
     3301 gtggagcggg acgccgtcgt cgcggactac ctggagtcca acgccacgca ccgccgctac
     3361 aaggtccgtc gcagcggcag cgcggactcc gcgtacacgc ccgaggtcat ggagctgctc
     3421 gacccgctct tcgacgcccg cgccgagtac ctggaagcgg cgttcgagag catcgaggag
     3481 acctgggggg acgtcgacac ctacctgcgc cagggcctgg acctctcccc cgggacccgg
     3541 gaacggctcc gcgagcgcct gctggactga ccggtaacac cggcccggcg gtgggcgccc
     3601 ggcggctcac gacttggcgc ccaccgtgaa cagcaggtac aggaacgcgg ccaggacatg
     3661 cccgagggcg atgtagatga tcagccggat ccacagggat cgggggaact tcgtctcgaa
     3721 gtcgctcatg gcagctctcc ggtcagcggc cccaggcaca gcgtggccgt gggactctgc
     3781 aacagggtgt ggacgaacag cagctcgacg ccgtcctggt cctcggcggc gaggcggtgc
     3841 ggggtgaggg agtcgaagtg ggcgctgtcg ccgggggcta gcagatgcgc cgtgtcgccg
     3901 agccgcagcc gcagccgccc cctcaggacg tacagccact cctccccggg atggacgcgc
     3961 acgatgtcgc cctgcgagcc gtggggcacg cgcacccgca gggcctgcat gccgcggccg
     4021 gaggctccgg cctgcgtgta cgtccatccg cccgcccgcg tgggctccat gtcggcggcc
     4081 cgcacgatcg cgtcccggtc ggcgaccgtc tcgccgagca gctcggagac ggtcgtaccg
     4141 tagatacggg cgagcgcgag gagcatcggc agcgagggct ggcggtgccc ggtctccagg
     4201 cgggacaggt gggccggcga gagtccggcg gcacgcgccg cggcctccag cgtcagcccc
     4261 gcacgccggc gcagggcgcg gagctggggc gcgacggcgg gcaggtcgtc acccggtccc
     4321 gtcggcggcg ggacgtctga ggcgttcatg cctccattga gcccgctttt tgcccgtgcg
     4381 gcaattttat tgcctcagag gcaataactc cccgccgtgg agcctcgccc ggttccggcc
     4441 gcggggccgc cccgcccggc agccccgcct gtttccgacc cccgtccccc gacaccccgt
     4501 ccccacacgc ctccctccgc cgcgccctgt tacgatcgag ccctgaattt gaacaagttc
     4561 aaaaaacagg ggataccatg tccgcgagca ccacgcccgg ccgggccgac gcacccgccg
     4621 tcggcctcgg ccccaccgca ctcgtcctgg ggaccgtggc cgccgcgggc gtgtggccga
     4681 ccctgacgtt cgccctgctg ccggtgatgc ccatcgccgg gggactcgcc gtcacgttcg
     4741 gcctgatggg cgtccaccaa gcccggcagg gcgtcggccg gctctggacc gccgtgacgg
     4801 gcaccgccct gggtgcggtc ggtttcctct acctcttcgt cctcctcatg gcgctgtccg
     4861 gctgaaccgg ccggccggcg gcctcgtggt cagcggttcg ccaccgcctg cttgatcagg
     4921 gtcttgccga agtcccacag caggccgctc ccgttgtgcg cgtcgtccat gacggcggtg
     4981 aaggcgtcca cgaaccggtc cacgtcggcc tcgtcgacga tcagcggcgg gatgagcttg
     5041 atcacctcca ggtggtcgcc ggagacctgg gtgaggatcc ggtgccgttg cagcagcggg
     5101 acgacgacca tctgggcgaa cagccccttg cgtgccgcct ggagcacggt ccagcggctg
     5161 cgcagcgcca gcgaggacgg ccggccgaac tcgatgccga tcatcaggcc ccggccgcgg
     5221 acgtcggcga gcagctcgta ccggtcgatg agcgcggtca gccgggactt cagcagctcc
     5281 cccgtcctgc gcaccccggc gacgatctgt tcgttctcca tcaccgacag cacggccagg
     5341 ccggccgcca tcgcctgggc gttggagccg aagctggccg agtggaccag gacccggtcc
     5401 atggacgagt agaccttcct gaagatccac tccttgccga gggtggcgcc gaccgggacg
     5461 tagccgccgg acagcgcctt ggccacgcac accaggtcgg gttcgacgcc gtcctcgtgc
     5521 tggtaggcgt agaagtcgcc ggtgcggccg agcccggtct gcacctcgtc gacgatgagc
     5581 agcgcccggt accggcgcag cagcccctga gcggcgcgca gatagccggg cggggtcggg
     5641 tgcacgccct tgccctggat cggctcgacg atcaggccgg ccacgtcgcc cttgctcaac
     5701 tcccgggcga gcgcgtccag atcaccgagg ggtacggccg tgtcgggcag cagcgggtcg
     5761 aagccgtccc ggaagccgtt ctcgccgttg accgagagcg acccggtggt caggccgtgg
     5821 aaggcgtggt cgcagtagag gatgcggggc cgtccggtgg cgtaccgggc gaacttcaac
     5881 gccgtctcga ccgcctcggt gccgctgttg ccgaagaaca cccggtccag gtgcgggctg
     5941 tgggccagca gccgctcggc gagcaggccg ggcagcggct ggcagtcgaa gcgggtgagg
     6001 tcggcgaggt ccatgtccag gacgtcgtgc agcgccctgc ggacgaccgg gtggtgacgg
     6061 ccgagcccca tcacaccgaa cccggcgagc atgtccaggt agtcgttgcc ctcgtcgtcg
     6121 tagaagtggg caccctccgc ccgctcgtag accttgtcga agccgatggt gtgcagcatg
     6181 cgcgggagct gcgggttgag gtgcttcgcg tgcagctcgt agcgttcggc tccgcgctgg
     6241 gcgagcaggg cgccgaggtc gaactcggtg gtcattgact ctccttggct gtgccgccgg
     6301 cgtccttgac agccagggcg gcgctgatcc ggccggcgat ctcgacgggc gtgagaccga
     6361 tgtcggccag cacctcgtca cgtctggcgt gtgcgaggaa ctgttccggg ataccgaacc
     6421 gccgcaccgg cacatcgacg tcggcgtcac cgagggccag ggccacggcc gaaccgacgc
     6481 ccgcggcacg gctgttgtcc tcgaccacgg cgaccgtccg gtgtccggcg gcgaggccgg
     6541 gcagggctgg gtcgacgggc ttgacccacc gcgggtccac caccgtgcag ccgaggccgc
     6601 gggcttcgag cagctcggcg gcctggagac acaccggggc catcacgccg acggcgacga
     6661 gcagcacgtc ggggtgtgcg gcgcggtgca ggacgtccat gccgccgacc cggtcaaggg
     6721 ccgggacggg cgggccggcg gactccttcg ggaagcggac cagagtcggc gcgtcgtcca
     6781 cggcgaccgc ctcgcgtagc tgtgcgcgaa gctggtcggg gtcgcgcggg gcggcgatcc
     6841 gcagccccgg gacgacctgg aggacggaca tgtcccacat cccgttgtgg gaggcgccgt
     6901 ccacaccggt gacgccggcc cggtccagga cgaaggtgac cccgcagcgg tgcagggcga
     6961 cgtccatcag tagctggtcg aaggcgcggt tgaggaaggt ggcgtagacg gcgacgaccg
     7021 ggtgcaggcc gccggtcgcg agaccggccg cggagacggc cgcgtgctgc tcggcgattc
     7081 ccacgtccca cacccggtcg gggaagcgtt cggcgaactc accgaggccc accgggtgca
     7141 gcatggccgc cgtgacggcg acgacgtcct cccgctcctc cccgatccgt acgatctcgt
     7201 caccgaacac cgaggtccag gaaggccccc gggagggcac gagcggtgcg cacgtcagcg
     7261 ggtccatcac gccgacggtg tggaagtggt cctcctcatg cgccagggcg ggctcgtagc
     7321 cgcggccctt ctcggtgagg cagtggacca ggaccggccc gtggaagcgt ttcgcccggc
     7381 gcagcgcgga ctcgacggcg ccgatgtcgt ggccgtcgac cgggccgacg tacttcaggc
     7441 ccaggtcctc gaacatgccc tgcggggcga aggcgtcctt gaagcccttc ttcgcgccgt
     7501 gcagggactc gtagagcgtg ttgccgacga ccggggtgcg ctggagcacg tccttgcccc
     7561 aggcgaggac cttctcgtag ccgtcggtgg tgcgcagggt ggccaggtgg cgggcgaggc
     7621 cgccgatggt gggggcgtac gaccgctcgt tgtcgttgac gacgatgatc agcggccggt
     7681 tcctggcggc ggcgatgttg ttgagcgcct cccaggccat gccgccggtc agcgcgccgt
     7741 ccccgatgac cgcgaccaca tggcccttct ccccgcgtac ctggcgggcc ttggcgaggc
     7801 cgtcggccca cccgagcgcg gtggaggcgt ggctgttctc gatgacgtcg tgctcggact
     7861 ccgcacgcga ggggtagccg gacaggccgc ccttgccgcg cagtttcgag aagtcctgac
     7921 gtcccgtcag cagtttgtgt acgtagctct ggtggccggt gtcccacaga atgcggtcgg
     7981 ccggtgagtc gaagacccgg tggagcgcga cggacagttc caccacgccc agattgggtc
     8041 cgaggtgacc tccggtcctc gacaccgcgt gcacgaggaa ctcgcgtatc tcgtcggtca
     8101 gttcgccgag tctcgcctcg gacagcgcct tcaggtcgtg tggtccccgg atgctctcca
     8161 gaatggtcac gctcgacgcc ctctcggtcc gtgccctgcc tcaaccactt gtgccgccgc
     8221 gccgcccccg accgccgtcg gcccggtccg ggtccgccgc gactgccggt gcggtgcgac
     8281 cggacgggcc ggcaccccgg gatgtccccg ggggacggcg gtcgtcgcgt cagtcgcggt
     8341 tgccggagac ggtctcgcgc atcgcccgca gcgactcctt cagggacccc atggtggcga
     8401 ggacggccgt gggctcgtac ccgcagtgcg ccatgcagtt ggcgcagcgc gggtccttgc
     8461 cgcggccgta cttgtcccag tcggtcttct cgatcagctc ccggtacgtc ggcacgtacc
     8521 cgtcgctcat caggtagcag gggcgctgcc agccgaagag cgagtagttg gggatcgccc
     8581 acgcggtgca cgggaagtcg accttgccct ccaggaagtc caggaagagc ggggagtggt
     8641 tgagccgcca cttgcggcgg ttgccgcccg cgaaggcctt ccggaacagc tcgcgggtct
     8701 gctcgacgcc gaggaagtgc tcctggtccg gtgccttctc gtaggcgtag gcgggcgaga
     8761 tcatcatctc gtcgacctgg aggtcgtcgt tgaggaagtt gagcacctcg atgatcgtct
     8821 gcggggtgtc ggtgttgaag aaggtcgagt tggtggtcac ccggaagccg cgccgtctgg
     8881 cctccttgat ggcctccacc gcctcgtcga acaccccctc cttcgccacc gactcgtcgt
     8941 gccgctcgcg cagcccgtcg atgtgcaccg cgaaggcgaa gtagggcgac ggcgtgaaat
     9001 tgtcgatctt cttgcgcagc agcatcgcgt tggtgcacag gaagacatac ttcttcctgg
     9061 ccaccaactg ccgtacgatc tcgtcgatct ggggatgcat cagcggttca ccgccggcga
     9121 tggagaccat cggcgcgccg gactccagca ccgcgcccac cgcctgcgcg accggcatgc
     9181 gctgcttgag cacaccggcc ggatgctgga tcttgccgca gccctcgcac ttgagattgc
     9241 aggcgaagag cggttccagc tcgacaatga gcgggaactt gtcccgcttg cgtagcttct
     9301 gttcagccag gtatgtagcg accttgatgg actgacgcaa cggcatggcc atctggctca
     9361 cctccggggg agcggcaaag aacggtgcca ttcgaaaaga gcgggaagaa cggaacggag
     9421 gacacggaaa gctgatattc caccgcgcac cgtgccgatc cggacgagtt cgtgttcggg
     9481 agcgtccacg accacccgga cggccgcagt tgggcgcggg cccgcgcgga cggccgcgag
     9541 gagcgtcgcc gccgactcca tgtcgaccgc gatcgcgccg gtcgcgagca ggtcggaccg
     9601 ctcgtgtccc cggaccacgt ggtcggagcc ggtgagcgga ccggtgtgca ccgtgcgtcc
     9661 gggcagccgg cgcacgagtt cctccaccag cgccgcggtg cccgcgcacg ggacggtccc
     9721 gcgcgggtcc cgggtctcct cggcgacgac gaggtcgccg gggtgcatgc cgggggcgag
     9781 tccggcgcag aagccggtgg ccaggacggc cgcgccggcc agggccggac cgccgaggtg
     9841 ccgggtgacg gagcgttccg ccgcgcgggg gcccatgccc gtgcggacga cggtgaccgg
     9901 cccgtccgcc ccgctccggt cgccggtgcg cagggcgagg tgctcgatgc cgagcgcgca
     9961 ggcgatcagc agcggggcgg cgacgggcgc ggctctcacc tcaggccccc ttggcctcgg
    10021 tgagcggttt cccggcccgg gcgagcagct tccgctcgaa ggggtccccg tgcaggtacc
    10081 ggccgagcgc ggtgagcggg aacacctgcc ggtagaggtg gtagttgatg gagaagtccc
    10141 aggggaagcc ggtgccggtg aagtacggct cgtcccaggt gccgtccgcc cgctgggtgg
    10201 cggtcagcca ccggatgccg cgctccacgg ccttggagtc ccgctcgccc gccgcgagca
    10261 gggccatcag cgcccacgcg gtctgggagg cggtggaggc gccccggccg ctccactcct
    10321 tgacgtactt gtaggagcgc aggtcctcgc cccagccccc gtcgtcgttc tggacgctct
    10381 ccagccagac cacggcccgc cggatcgccg ggtgcgagcc gggcagtccg gccgcggtga
    10441 gcgcgggcac caccgacccg gtgccgtaga tgtagttgac gccccagcgg ccgaaccagg
    10501 agccgtcggc ctcctgttcg gcgagcagcc aggcgatgcc gcgccgggtg cgcggatcgt
    10561 gggccaggcc ctcggcggcg agcatctcca cgacgtgcgc ggtgacgtcc gcggacggcg
    10621 ggtcgatgac ctcgccgaag tcgcagaacg gcagccggtt ggggaacgga ctggtgttgt
    10681 cggcgtcgaa cgcgccccag gcgccgttct tcgactgcat gcccaggttc cagcggacgg
    10741 cccggccgat ggcccggtcc acgcgctcgg ggtcgtggtg gcggacccgg cgcagcgcga
    10801 gcgcgacctc ggcggtgtcg tcgatgtccg ggtagttgtc gttgtggaac tcgaacgccc
    10861 agccgcccgg cgggagatga gggcgcttga cggcccagtc gccgggccgg acgatctcct
    10921 cgccgagcat ccagtcggct gccttgacca gttgcgggat ggtcgaccgg gagtccggcg
    10981 tcgacgaggg cgatggtggc caggcaggtg tcccacaccg gggactggca ggcctcgatc
    11041 atccgggcgc cgtcctcgcg ccagacggcg aaacggtcca gggaggcgag gccctcacgc
    11101 atcaccgggt gctggaggtc gtacccgagc aggtacaggg cgatgaccga gtacacggcc
    11161 gggggctgga tgccgcccca gcagccgtcg ttctcctggc gttcgatgat ccagcgggcc
    11221 gccgagtcca tcgccgcctt gcggacccgg cgcggggcga ccttgcgcag ccggtgcagc
    11281 gccttgtcca gacgctggaa ggccccgtcc caactggtca gcggggcgcg gggcttgggc
    11341 ggaacggggc gggcggggtc ggtgtgcaca gttcgtccag cgggaagggc gccgggcgga
    11401 ccgggcgctt ggccgagacg atggtgagcg gcacgatggt ctgccgggcc cagcagccga
    11461 agtcgtagat gttgagcggc atccaggtgg ggaaccagat gagttccggc gggagttcgg
    11521 gcaggtcctc ccatctccac cagccgaaca gggcgagcca gatccgggtg aacacgcggg
    11581 cggcggcgat gccgccgcgc tcgcggaccc aggccgacgc cttcgccatg tggggggcgt
    11641 cgggcgcgtc accggccagc cggagggcga cgtaggcctc gacggtggcg gacaggtcac
    11701 cgggcccgcc gtagaaggtg gcccaggtgc cgtcgtcccg ctgctcgccg cggatgaacc
    11761 tggcggcggc ctgcgtggtg ctctcgtcca ggatgtccag gaactgacgc agcagcaggt
    11821 cctcggcgtc catggtgacg ttcgtctcca ggtcgccctt ccaccagccc tggacgtcct
    11881 gccgggagag cagggagtcg gtggcgcgct gcgcggcgcg tgcggcggct tcccgtaccc
    11941 cggccgcctc ggggatggtg aaggtggtgt cgctggccgc ggcagcgcgg gacggcaagg
    12001 tcgccccggt gcttccgtcg gtcgtcgctg tcatggcttc cccttcgtgc agtgcgaagt
    12061 cgtgctgctg tgggaacgcc gtcggccggt gtgcgaaagc tcgtcaccgg ccggcgacta
    12121 cgcgaggcct gtcgagccga ggacggtcat ctcttccgta cgacgacgaa gtcggcgagc
    12181 gccgtgaagg agtcccgtac ccggtcgggc atgtcgacgg cgtcgagggc ctcgacggcg
    12241 atggtgtgct gacggcgtgc ctcccgcgcc gtccactcgc ggccgccggc ctcctcgatg
    12301 agggccgcgc gggccgcgaa ctcctcctcg gagaagttct cgaagtcgct gctcttggcg
    12361 tcggcggcga ggatctcgcc gagctgctcc gaggcggggc cgccggccgc gagcgcggcc
    12421 accaccggca gggacttctt gcgctggcgc aggtcgctcc acgtctgctt gccggtggcc
    12481 tccgggtcgc cccagatgcc gaggaggtcg tcgacggcct ggaaggccag gcccaggtgg
    12541 tacccgtagc gctccagcgc gtcggcggtg gcgtcgtcgg cgccgccgag gaccgcgccg
    12601 atggaggagg cgcaggcgag cagggcgccg gtcttgttgc cctccatctc caggcactcc
    12661 tcgacgctga cgcggtcgcg gtgctcgtag gagatgtcct gggcctgacc gtcgatcagg
    12721 gcgcgggtgg cggtggtcag ccggcgggtg gcgcggccgg cctcgacggt gccgagttcc
    12781 agcaggacct cgttggcgag ggcgaacagg gcgtcgccga ccaggatggc ctgggcgggg
    12841 ccgtgcacct tccagacggt gtcccggtgc cggcgctgct cgtcgccgtc catcaggtcg
    12901 tcgtgcagca gggagaagtt gtgcaccagt tcgacggcga ccgcgcccgg gatgcccgcc
    12961 tcgggtgcgg cgccggtgac ctcggcggag agaacggcga gcgcgggacg gacggccttg
    13021 ccgccgtcac cgtcggccgg gttgccggcg gcgtcgatcc agccgaagtg gtaggcggcg
    13081 acggtgtcca tgggaggcgc caggcggtcg acggccgcac gcaggaccgg tgtggccagg
    13141 gtccggccgc gctccagcaa cgcggtcacg tccaccgcgg cccgtggagc gggcgtcgag
    13201 gccgggggca cagtgggcac agtctctcct cttgttgcgg taccgggggt gcgggggccc
    13261 gccgcctgct gatcgggcat caggccgcct cctcgaatcc gaagaggcgg cgggggcggg
    13321 gccggcccag ggcgccgagc gcggcgtcgg ccgcgctcac tccactgcgg accgcactct
    13381 ccatggtcgc gggccacccg gtggcggtcc acgctccggc caggtacagg ccggtggcct
    13441 tggtgcgggc gccgggccgc agccgcccga cgccgggggt gggggcgaac gtggccgtgc
    13501 gctcccgggt cacgaagaag tcctccacca cggcggtacg cgcccccggg atcagtcgtg
    13561 ccagctcggg caggtagcgc tcgcggagtt cggcgaccgg ggtgtcgatc tcgtcctgcg
    13621 cggcggactg ggacagggcg aggtactggc cggtgcgcag tcccgaggcg tcggtgcggt
    13681 cgaagaccca ctgcaccggg gtgccgagcg cggcgaagaa cggtccggcc aggacccggc
    13741 ggtcgtagac gacgtggacg ttgaggatcg gcgcggtgcc gatctccagc agccgctgcg
    13801 gcgcgtcgag ggcgccggac ggcagcagtt cgtgggcctc gcgctggggt acggcgagga
    13861 cgacggcgtc ggtctccagc gtctcgccgg ggagctgaac gctccaggac ccgttcgcgt
    13921 ggagagagag ggaggtgacg cgtgcacgga cctgggtacg cacgcccgcg gagtcgagcg
    13981 ccctgcgggc cagccggtcg tgcagttcgc ccagcgggac gcgggcccag ccgatgtcgg
    14041 ccgcgccagg gtcggacagc agaccggtct tgaacaccat cgcggcgagc ccgagcgaga
    14101 cgtcgccggc gaccgcgttg agggtggcga ccccgaccag gtcccacaga gcctcgacgg
    14161 cgcgtgccga ctggccgtgg gcggccagcc agctaccgaa gtcctgtgtg tccagggcgg
    14221 gatcggcgag gtcgagtccc ttcagcgcga gcgcggcacg cccgacggcc gcgcgctcgg
    14281 cgagcgagag gtgcggatag gcggccaggc tgcgccccag gtggaggggg acgggcagcg
    14341 ggtcgcgccg cagccggccg agccgcctgc ccgcgggctt ggtgacgtcg acgacgggca
    14401 cgtccaggcg gtcctggagc ggtgcgaggg ccgcgccccc gatccggtcg aggaaccagc
    14461 ggtaggcggt gcagcagcgc aggtagacgt gctggccgtt gtcgacggtc agctcgccgc
    14521 gccggaagga gaaggcgagg ccgcccagcc ggggtctgcc ttcgagcagg gtgacgcgga
    14581 cgccggcgtc ggcgagggcg agcgccgcgg tgatgccggc gagtccgccg ccgaccacga
    14641 cggcgctgcg ccccgccggc tgcggggtgg cggcatgcgc cggtgcgggg cgtgaaccat
    14701 cgctcatcgt gcgtccttcc gtgcgtgccg gacgtgctgg tcgaacggtg cacgcccggc
    14761 cgtcgcagtg agggacgcca cgccgctgcg cggggttgcc cggccgctgc cgtccggtcc
    14821 ggggaggtcc atcaggcgcg cctcctgacg gaccgccggg agacatggcg ggtcacgtgc
    14881 cgggtgtcga gtccggacag gccgcgcacg gcgacgtagg ccttctcgtg cccgggcagc
    14941 gagacccggc cgcgcagcac ggcctccggg tcgcgctcga tgcggtccag cagccggcgg
    15001 tagatgccgg ccatcgcggc cacacaggca ccgctgcgcc ggtcgagcat gggcagcagc
    15061 cggtagccct cggcgaacag ggcgcgggcg cggcgcactt cgaagtgcac gaggcccgcg
    15121 aagtcggagc cgtccggtgg cgtcggcccc tggaacccgt ccgagcagcc gaacttggcg
    15181 aggtcgtcgg cgggcagata ggtacggccg tcctcggcgt cctcgcggac gtccctgagg
    15241 atgttggtga gctggagcgc gagcccgagg gtgtcggcgt actcgggggc acgctcggcg
    15301 ccgcgcgccc cgggttcggt gccgaacacg ccgagcgaga ggcggccgat ggcaccggcg
    15361 acacaccggc agtagacctt caggtcgtcc caggtctcgt aggtctgtcc gcgcacgtcc
    15421 atccggacgc cgtcgatcag ctcgtcgagg ccgccgagcg ggatcgggaa ggcctgtgcc
    15481 gcgtgggcga gggcgacggc caccggatcg gtgtcgtcct cctcgacctt gccgtccctg
    15541 acccgtgcga gcagcgtccg ggtgtcctcg aggcgggccg gtctgacctc gcgggccagg
    15601 tcgccgtcgc cgatgtcgtc cacgcgccgg gagaacgcgt acagcgccga catggcgcgg
    15661 cgtttggccg tcggcagcag cctgatgccg taggcgaagt tccgggcctg ctgcccggtg
    15721 acggcctcgc agtagctgta ggcggcgagt accggtgcgg agacgtgcgg cggagaatcc
    15781 acggtccgga tcacccctct cctcgcagga tcacgcccgc ctcacgcagc aactggaacg
    15841 tgccgggctc gggcgggccg ggaagtacgt cgaatccggc ggcggcgatc gcccggatcg
    15901 ccgccctccc ccccgccacg aatcctgcga gcagcagttt cagcctgccg tggacgctac
    15961 ccaccagggg ggcgccttca ttcagcagat cgcgggcgcg ttgtgcttcg tacgcgacca
    16021 gggcgcgcac cgatgcgccc gcggttctcg cggcgaggtc cgtttcccgg acgtggaagc
    16081 gcttcatgtc ctgcgcgggc aggtagatcc ggtcgcggcc gaggtcctcg gcgacgtcct
    16141 ggaggtgctc cacgatctgg agggcggtgc agatcgcgtc ggagagccgg atccgctcgg
    16201 gggtcgaggt gccggtgacg gcgaggacga ggcggccgac ggggttggcg gacagttcgc
    16261 agtaggcgag gaggtcgtcg taggtctcgt agcgggtgac gagctggtcc tggcggttgg
    16321 cggcgatcag cgcgaggaac ggttcggggg tgagggcgtg gcggcggacg gtgggctgga
    16381 ggcggcgcag cagcggatgg cgcggggtgc cgtcgaagac gcggcgcagg tccgtctcga
    16441 aggcgtcgag gagggccggc cggtcctcgg ccgcgtccgg cgacacgccg agcagacggg
    16501 cgtcgccgcc gccgggggcg aggtcgccgt cgccgatgtc gtccaccaga cgggcgaagc
    16561 cgtagacggc catgaggtcc tcgcgccacg cccggggcag gaagaagggg gccacgggga
    16621 agttctcgct cgcggccttg tccagggtgg cgcgttccag gtccggcgcc gggtcggtgg
    16681 ccgtcatcgc acgctgcccg gggcggggac ggcacatgct gcgtcgagca ggggagtctc
    16741 cgtagccatt gccgtcacat ctcccgttct acactgccga cctaataccc actatttcgg
    16801 acacgccgcc cgtccgcgcg cgaggcgccc tgacggcggg tgtcgcgcgt tatcgcccca
    16861 cttgccgggt tccggcgccg gtacagctta cgttgtacaa cgcagcacgg accgccgggg
    16921 tgtcctgcac atcacaacaa cacaccgatt ggctccaaga ttcctaccgg cagccggagt
    16981 tgacgtttcc tttgcagacg cggggccccg ccggacggat accggcgggg ccctggccga
    17041 aacgggtcac ttgcccgtga acttctcgta ctccttcagg acctcgtcgg tcggcccgtc
    17101 catgcgcagc tcaccgcgct ccagccacag cacgcggttg caggtgtcgc ggatcgactt
    17161 gttgttgtga ctgaccagga acaccgttcc ggcctccttg cgcagttccc ggatgcgctc
    17221 ctccgagcgc ttctggaact tgcggtcacc ggtggccagc gcctcgtcga tcatgagcac
    17281 gtcgtggtcc ttggcggcgg cgatggagaa ccgcagccgg gccgccatgc cggaggagta
    17341 cgtgcgcatc ggcagggtga tgaagtcgcc cttctcgttg atcccggaga agtcgacgat
    17401 gtcctggtag cgctccttga cctgctcccg ggacatgccc atggcgaggc cgccgaggat
    17461 gacgttgcgc tcgccggtga ggtcgttcat cagggccgcg ttgacgccga gcagcgaggg
    17521 ctggccgtcg gtgtagacct tgcccttctc cgcgggcagc aggccggcga tggcgcgcag
    17581 cagggtggac ttgccggagc cgttggagcc gatcaggccg atggcctcgc cgcggtaggc
    17641 gacgaaggac accccccgca cggcgtgcac cttgcgcacc ccgcgcgccg tgtcgtcgga
    17701 gccgcgccgg aggatccggc tcagggccgc cgtcgcgctg cccttgccgg tcctggcgcc
    17761 gttgacgcgg tagacgatgt gcagttcgtc ggcgatgacc gtcgggcgac gctcgtcgtt
    17821 gtcgtgttca gccacggccg taccgctcct ccgccttcca gaagtacacg aagccgccgg
    17881 cgaagaccgc cacggcccag aacagcgcga tgacccacac gtgcggcggc aggttcgagg
    17941 caccgtagcc gtcgatcagc gcgaaccgca tcaggtccat gtagatcgcg gccgggttga
    18001 cctggaggag ccggacgatc cactcggggc gcccctccag catcttgttg atcgagaaca
    18061 tgacgccgga ggtgtacatc caggtgcgca gcaggaacgg catgagctgc gcgaggtccg
    18121 gcgtcttggc gcccatgcgg gccacgatca tcgccagtcc ggtgttgaac aggaactgca
    18181 gcaccagcac gggcaggatc agcagccagg acgggctcgg gtagctgccg aagccgatcg
    18241 ccacgacgaa cagcacgatc atcgagaaca gcagttgttg gagctgctgg agcgagaagg
    18301 agaccggcag cgaggcgcgc gggaagtgca gggcccgcac cagaccgagg ttcccggaga
    18361 tggcccggac ccccgacatc accgaactct gcgtgaaggt gaacacgaac acgccggtga
    18421 ccaggaacgg gatgtacacg tcccgggaca tgccgcggct ggcgtgcagg atcagcccga
    18481 agatgaagaa gtacactgcc gcgttcagca gcggcgtggc cacctgccaa agctggccca
    18541 gcttggcctg gctgtactgg gccgtcagct tcgcctggga gaaggcgagg atgaagtggc
    18601 ggcgccccca gagctgacgg acgtactcca cgagcgaggg ccgggcaccg ctcacggtca
    18661 gcccgtacct ggcggcaagc tggtccgccg tcactccctc gtcgggcgac ggggccgcgg
    18721 tcaccgcgac cgtgccgtcg tgcgtggtct cactcacagg tggaaacttt cgtcttcggg
    18781 ttcgcgttcg agttcgtcgt ccggtgcgtc cgtcggcggg cgcgcatgcc ctcacggacg
    18841 agcttgtcag atgaccgggg gacggcccag tcgggtgagg cgccacaccg tacgccagcg
    18901 catcgggcgg cgcggaccgc acggtgtggc ccagccttcc cggaacccgc cgaaccaggc
    18961 cttcagggcc ggccgcgaag ggcggcgcag gagggtgagc agcagccaga ccccgaggta
    19021 gacggggacc aggagggcgg gcaggttgcg gcgggccagc cagacgcggt tgcgggcgac
    19081 catgcggtgg tagaccgcgt gccgcgaggg cgcggtcgtc gggtggtaca gcaccatgtc
    19141 cgaccggtag tcgatcatcc agcccgcgtc gagggcccgc catgccaggt cggtttcctc
    19201 gtgggcgtag aagaactcgt ccgggagccc gccgacctcg gcgaagacac gggtgcgtac
    19261 ggcgttggcc ccgccgagga aggtggtgac ccgggaggaa cgcatcgggt cggcggcccg
    19321 cagccggggc acgtgccggc gctgggtctc gccggtgccg gggtcggcga tgcggaagct
    19381 gatgatgccg agcgccgggt cggcggcgaa ggcctcccgg cacagctcgg cggtgtcgtg
    19441 ccgggcgagc aggccgtcgt cgtcgaggaa gagcaggatg tcgacgtcgc gcccactggg
    19501 accgaaggcc tcgatgccga cgttgcgccc gccggggata cccaggttct cgggcagctc
    19561 gatggtgcgt acgccggccg gcacgtccgg gaccggcgag ccgttgccga cgacgacgac
    19621 ctcgacgggg tcgccgtcct gcttggcgac ggagtcgagc agggcccgca gctcctcggg
    19681 ccggttgccc atggtgatga cgacggcgcc gaccttcacg gcgctcaccg cagcctgctg
    19741 gaggcgagga cggacaccag gtgcaacagc gtctggagca cggcgatgcc ggcgaggacg
    19801 gcggtgccca gacgggtgaa gaacaggtcg ccgcgggcct ggtccgcgat ggcgaggacc
    19861 aggatgagca gcgaggcctc gatgccgagg atgagccggt ggaaccgcag cgccgaggcg
    19921 gcccggcggg ccagcgccat gcccgcggaa cgcggctcgg cgacgcccgc cgcgtcctgc
    19981 acgggcggca tcccggcctg gtggcgggcg acgccgacca ggtcggtctc ggccttgatc
    20041 aggatggcgc cgagcgcggc gagggtgccg aggaaggccc acagccagtc gatacggccg
    20101 ctgccccaca ggtcggcggc gcgcaggccg aggccgacca gcacggccgc gtcggtgagg
    20161 taggcgccca cgcggtccag gtagaccccg ccgagcgagt actgcttctt ccagcgggcg
    20221 atctcgccgt cgacgcagtc cagcaggagg tagagctggg tggcgacgat cccgaggacg
    20281 gcacccgcga tccccggcac cagcagggcc ggggccgcga gcacaccgca gacggtcatc
    20341 aggtacgtga gctggttggg cgtgaccctg gtgttcacca ggtagcggtc gacgcgcagg
    20401 gacacctcac gcatgtagag gcgtcccgcc cagtgctcac cgctgcgccg gtccttcacc
    20461 cccgcggggt ggacgaccgg acggagttca gctaccgatg gccttgacat agtcggcgta
    20521 gatgtccttg atctggttcg tcttgaggtc gaggtgttcg atgatcgtgt agcggccggg
    20581 cctggtctcc ggggcgaact ccaccacgcg gacgaactcg tccaccgtga agccgatctc
    20641 ctccggcagc accggaagcc cgtgccggcg cagcaccccg gccatgtacg ccgcctcctc
    20701 gtgcgcgccg cgcaggtaca tcgcgaaggc ggcgccgaga ccgcactgct caccgtgggc
    20761 ggctgcccgc ttgggatgga gcaggtcgaa ggcgtggttg atctcgtggc aggcgccgga
    20821 ggacgggcgg gagtcgcccg acaccgacat ggcgatgccg gtgaggacca gcgcctcggc
    20881 cagtacctgg aggaagccgt cgtcgccgac cccgcccggg tgcctgagca ccgcctcgcc
    20941 ggcctggcgg gccatggcgg cggccaggcc gtcgatcttc tcgccgttga cgcggtggga
    21001 cagctcccag tccgcgaccg cggagatgtt ggagatggcg tcgccgatgc cggagcgcac
    21061 gaaccgtacg ggcgcctcac ggatcacgtt caggtcgatg acgaccgcga tcgggttcgg
    21121 cacgccgtac gagccgcggc cggcgtcgtt gtcgagggtg gccaccggcg agcacagccc
    21181 gtcgtgggcg aggttggtgg cgacggcgac cagcggcagg ccgacgcggg ccgccgcgaa
    21241 cttggcgcag tcgatgatct tcccgccgcc gaggccgacg accgcgtcgt agtggccggc
    21301 ctttatgtca cccgccagcc ggaccgcgtc gtcgatggtg ccgccgtcga cctcgtacca
    21361 ggtggcgccg ggcagcgagg gggcgatccg gtcgcgcagc cgggcgcccg atccgccgct
    21421 gacggcgatg gcgagccggc ccgactgcga gatgcgctcg tcggcgagga caccggccag
    21481 gtcgtcgagg gcacccgggc ggatgtccac gacgaccggc gagggaatga gccgggtcag
    21541 tactggcacg cgatctcccg tccccgggcg aggtcgtcgt ggttgtcgat ctccacccac
    21601 ggcacatcgc cgatcggcgc gacgtcgatc ctgaagccgc ggttcaccag ctcctggtac
    21661 ccgtgctcgt agaactgctg cgggtcgctc tcccagacgg ccttcagcgc gtccgccagc
    21721 tcgggggcgg cgtcgccctc gatcagggtg acaccgatgt actcgccggt cgcctcggcc
    21781 gggtccatca gcttggtgat cttacggacg cccttggcgg ggtcgacgac gaccttcatc
    21841 tcctcgtcgg cgagggactt gacggtgtcc agcgcgagga tgatccgcct gccctcgcca
    21901 cgggcggcga gcagcgtcct ctcgacggag accgggtgca ccgtgtcgcc gttggcgagg
    21961 atgacaccgt ccttcagggc gtcacgaccg caccacagcg agtaggcgtt gttccactcc
    22021 tcggccttgt cgttgtcgat gagcgtgagc ttcaggccgt acttctgctc cagggccgcc
    22081 ttgcgctcgt acacggcctc cttgcggtag ccgacgatga tcgcgacctc ggtcagcccg
    22141 atctcggcga agttgccgag ggtcaggtcc aggaccgtgg gttcgccctc tatgcccgcg
    22201 gggcccaccg gcaccagagc cttgggaagg ctgtcggtgt aggggcgcag acgccgtccg
    22261 gcgccggccg ccagcacgag gccgatcatg cgggttctcc ttcatcgtgt acggcgggcg
    22321 cgccgccctt gtgggcggac acccagaagc ggatgctctc gacgagcacc agcagggcga
    22381 cggccacggc gaggaccgtg agcgcggcct tgaactgcga ggcggtgagc accgcggcca
    22441 ggacggtgac gagcagcgtc cgcccctcct gccccccgac ggcacgcacc agccaggccg
    22501 ggggcgctcc ggcgtcgccg cggatgcggt acaccgtgtc gtagtgatgg taggcgacgg
    22561 cggccaccag gccgaaggcc gcgggaagcg ccccgttcac ccccgctttg ccggccaggg
    22621 cgagcacggt gccgtactcg gcggcccgga agaagggcgg caccagccag tcgagggcgc
    22681 ccttgagggg gcgggcgacg gcgagggcgg aggtcaggac gtacacgagg gccccggcga
    22741 ccggtacgac gccgccgaag ccggtcagcg ccgagcaggc cacgaccgct gcaccgccga
    22801 gcagggcgac ggcgggcacg gcgagaccgg gcaggccccg cccggccacg cgcccgaccg
    22861 cctcggcgag cgggccggag tcggtgaggt cggcgagcgc ctgcgccgcc cggtcggtgc
    22921 gccgggcccg ccgggtcacc gagcgcagca cgcggccggc cgtggtgtag gtggccgcga
    22981 aggcgcagcc gacgagcagg acgtagaagg tgatccgcgg cgtcgtcacg gccgtgagga
    23041 cggcgatcat cgcccagcgc tcgccgatcg gcagcacgat catgcggcgc agccagaccg
    23101 tccagccgac actgtcgagc ttgtcggaga gcgcggcggt ggggctggtg ttggcggtgg
    23161 cgtcgtggtt ggcctcgttg aaggagaagt cgaccacgtg ccggcaggtc tggaggatca
    23221 tcgcgccgag ggcgagggcc cacacgtcgt caccgccgcg ggccgcgccg agcgcgaggc
    23281 cggcgtagta ggcgtactcc ttggcccggt cgaaggtggc gtcgagccag gcgccgagcg
    23341 tggagtactt cagggcgtag cgggcgagct ggccgtcggt gcagtcgagc acgaaggacg
    23401 cgatgagcag cacgccggcc gcgacgaagc cgccgcgggt gccggtggcc gcgcagccgg
    23461 ccgcgatcag ggccgtgagc agcgaggcgg tggtgacctg gttcggggtc agcccccggc
    23521 gggcgcacca gcgggcgagg tagcgcgagt aggggctgat gaagaacgtg gtgaagaagc
    23581 cgtcgcgggc cttgacggcc gacttcaggc gtacggcctc gtcgtccacg gcggctacgg
    23641 cctgccgggc ctcgttgcgg gcctgcgggt cggcgggcac ggtggcgacc aggctgccca
    23701 gctcgggccg gtgcaccgcg ccgccctcgg cgtcgagggc ggtgacgacg tggtcggcga
    23761 ggctgtccgg ggcgagcgcg ggggcgccgc ccggggcgag cggcgccggc tcgccggccg
    23821 taccggtgcc cgcggaggtc tcgcgggcca cggcccgggt gagcgcctgc cgggcggccg
    23881 gctgggcggt gacggctccg gggacggcgg cgagcgggaa gcgcgggtcg gtcaggccga
    23941 ggcgcagggc gtgcgggtgg ccgacgaagc gggagtcgac cagggccacg cgccggtcgg
    24001 cgggcaccgc ggccagcagg gcctccgcct cggcggcgtc ggcggccaca cgcacgtcga
    24061 agccgaggga ccgcagatcg ttctcgagtg acgatccggg caccggctga ccggtgacga
    24121 tggcggtcga caaccgaact cactccctgg gtgccggcgc gcgggcgccg gtcttctgcg
    24181 tggtggggcg ccctgcctgc ggcacccggg cggcatgtcg gcagaggcta tcggatgggc
    24241 cggaggccgt gttcaccggc cgttcacggc ccggcccacg ggggctgccc cggcctttgc
    24301 cgcgatcatc atcggggatc cggggcccgg cccacaaacc cgtgggcgca gacccgggca
    24361 tccgggacac cgggcggctc ggcatagggt gggcgaccat gacgtggctg atcaccggcg
    24421 gagccggata catcggggcg cacgtggcac gggccatgac aggcgccggg gagagcgtcg
    24481 tggcgctgga cgacctgtcg gccgccgtgc ccgcgcggct cccggccgag gtcccgctcg
    24541 tccggggctc gacgctggac ggggcactgc tgaagcgggt cctcaccgag tacggcgtga
    24601 cgggcgtcgt gcacctcgcg gctcgcaagc aggtcgcgga gtcggtggcg cagcccaccc
    24661 gctactaccg ggagaacgtg ggcgggctgg ccacactgct ggacgcggtc gccgaggcgg
    24721 gcgtcggccg gctgctgttc tcctcgtcgg cggcggtgta cggcaacccg gacgtggacc
    24781 tgatcaccga ggacaccccg tgcgccccgg tgaacccgta cggcgagacc aagctggccg
    24841 gggagtggct ggtgcgggcg gcggggcggg cgcacggcat ctccaccgtg tgcctgcgtt
    24901 atttcaacgt ggcgggcgcg gcggcgccgg aactcgcgga cacgggggtg ttcaacatcg
    24961 tgccgatggt cctcgaccgg ctcacccggg acgaggcccc gcggatcttc ggcgacgact
    25021 atccgacgcc ggacggcacc tgcgtgcggg actacatcca tgtcgccgat ctcgcggagg
    25081 cccacctcgc ggcggcgcgg cggctggccg acggcgacgc cgccggtgac ctgacgctga
    25141 acatcggccg gggtgagggc gtctcggtgc gcgagctgat cacggtcata ggggaggtca
    25201 ccggggaccg cagggcgccc gtggtggagg gccgccgccc cggtgacgcg ccccgcgcgg
    25261 tggcctcggc cgagcgggcc gccgaggccc tggggtggcg ggcccggcgc ggggtgcggg
    25321 agatggccga gtctgcctgg cagggctggc gcctgcacca cggcgggtga accggcacgg
    25381 cacgcggggc gacggggccg cagcgctctg acctgcggaa cgtttccgca ggtcagggca
    25441 catgacaacg gtgttcagtg ccgcgttgcc cgataccccc gccccgtagt tgactggcct
    25501 cccggcaggc acacggaagg cggtagtcat gggggcaggg cacgaccacg ggcacgggca
    25561 ctcccacgtg ccggccacgg gtacggccac ggccgcgtac cggggccggc tgcggatcgc
    25621 gctgggcatc acgctcacgg tcatgctggt cgagatcgcc ggcggcctgc tcgcggactc
    25681 gctcgcgctg atcgcggacg cggcgcacat ggcgaccgac gccgtggggc tcggaatggc
    25741 actgctcgcc gtccacttcg cgggccgccc gccgagcacc aaccgcacct tcggcctcgc
    25801 ccgcgcggag atcctggccg cgctggccaa ctgcctgctg ctgctcgggg tcggcggata
    25861 cgtcgtgtac gaggcggtgc agcggttcgt cgagccggcg gacacccggg ccgggctgat
    25921 gatcgtgttc ggtctggtcg gcctggtcgc gaactcggtc tcactggtgc tgctgatgcg
    25981 cgggcagaag gagagcctga acgtgcgcgg cgccttcctg gaggtggcgg cggacgccct
    26041 cggctcggtg gcggtgctga tctcggcgac cgtgatcctc accaccggct ggcagcccgc
    26101 cgacccggtc gcctcgttgg tgatcgggct gatgatcgtg ccgcggaccg tcaggctgct
    26161 gcgcgagacg ctcgacgtcc tgctggaggc ggcgccgaag gacgtcgaca tggcggaggt
    26221 ccgggcgcac atcctggcgc tggacggcgt ggaggacgtc cacgacctgc acgcctggac
    26281 gatcacctcg ggcatgccgg tgctgtcggc gcacgtggtg gtcagctcgg aggtgctgaa
    26341 cgccatcggc aacgagaaga tgctgcacga actccagggc tgcctgggcg accacttcga
    26401 cgtggagcac tgcaccttcc agcttgagcc gggcgggcac gcggagcacg aagcgcggct
    26461 gtgccactga ccgtccgcac ggccgttcga ggcgccgcgg gcggttcccg gtggcggccg
    26521 gtgggcacga tgacccaccg ggtccggctc cgggtgccgc gccgtgcgcg gggacgtccc
    26581 gtgccgggaa gtgccgggag tgccggattc gtacggcaga cttggggtgc gaagaccgag
    26641 gcgaaggatg ggtatgccga tcacacctgc caccgcgacg cacagct
//
