LOCUS       NZ_RAII01000001        15583 bp    DNA     linear   CON 15-MAY-2024
DEFINITION  Streptomyces sp. E1N211 s-211_S3_L001_R1_001, whole genome shotgun
            sequence.
ACCESSION   NZ_RAII01000001
VERSION     NZ_RAII01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. E1N211
  ORGANISM  Streptomyces sp. E1N211
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7318313)
  AUTHORS   Vicente,C.M., Thibessard,A., Lorenzi,J.N., Benhadj,M., Hotel,L.,
            Gacemi-Kirane,D., Lespinet,O., Leblond,P. and Aigle,B.
  TITLE     Comparative Genomics among Closely Related Streptomyces Strains
            Revealed Specialized Metabolite Biosynthetic Gene Cluster Diversity
  JOURNAL   Antibiotics (Basel) 7 (4), 86 (2018)
   PUBMED   30279346
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7318313)
  AUTHORS   Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-SEP-2018) Dynamique des Genomes et Adaptation
            Microbienne UMR 1128, Universite de Lorraine - Institut National de
            la Recherche Agronomique, Faculte des Sciences et Technologies
            Boulevard des Aiguillettes BP 70239, Vandoeuvre-les-Nancy F-54506,
            France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC Genomics Workbench v. 6.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50x
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003671735.1-RS_2024_05_15
            Annotation Date                   :: 05/15/2024 02:33:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,941
            CDSs (total)                      :: 6,866
            Genes (coding)                    :: 6,131
            CDSs (with protein)               :: 6,131
            Genes (RNA)                       :: 75
            rRNAs                             :: 3, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 736
            CDSs (without protein)            :: 735
            Pseudo Genes (ambiguous residues) :: 0 of 736
            Pseudo Genes (frameshifted)       :: 138 of 736
            Pseudo Genes (incomplete)         :: 673 of 736
            Pseudo Genes (internal stop)      :: 17 of 736
            Pseudo Genes (multiple problems)  :: 87 of 736
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:49:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3064878
            Orig. end                         :: 3080461
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RAII01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..15583
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="ectoine"
                     /product="butyrolactone"
                     /region_number="13"
                     /rules="ectoine_synt"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..15583
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="ectoine"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10399
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10399
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5399](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5399
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    1825..1836
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.14"
                     /tool="antismash"
     gene            <2139..2327
                     /locus_tag="EBH12_RS35675"
                     /pseudo=""
     CDS             <2139..2327
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009332786.1"
                     /locus_tag="EBH12_RS35675"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="RWVIERTMAWLSGYRWLSPRYERGPRNYLAISDSPLPCAATRRLI
                     HLTTWDTVGCAACSGVI"
     misc_feature    complement(2760..2773)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.97"
                     /tool="antismash"
     gene            3021..3497
                     /gene="ectA"
                     /locus_tag="EBH12_RS14325"
     CDS             3021..3497
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157665.1"
                     /locus_tag="EBH12_RS14325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_114875803.1"
                     /transl_table=11
                     /translation="MAVPTVKDGAGVWRIARGSGVLDVNSSYCYLLWFRDFARTSVVAL
                     ASGGVPVGFVTGFRRPEQPDTLVVWQIAVDGGQRGRGAAGAMLDHLTARLAVDGALRFV
                     ETTISAGNAASHRLFRSFARRHGAPLVRDLLFPAEFFPDTHDAEFLYRIGPLLR"
     gene            3558..4853
                     /gene="ectB"
                     /locus_tag="EBH12_RS14330"
     CDS             3558..4853
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (29-365). E-value: 1e-69.
                     Score: 227.1. Matches aSDomain:
                     nrpspksdomains_EBH12_RS14330_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156968.1"
                     /locus_tag="EBH12_RS14330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_114872585.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.6e-73, bitscore:
                     246.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPHPASHVFERLESEVRSYCRGWPTVFDRALGSRLYGEDGRPF
                     LDFFSGAGALNYGHNNPVLKRALVDYIERDGVTHALDMSTAAKRAFLETFQEVVLQPRE
                     LPYKVMFPGPAGTNAVEAALKLARKVKGREAVVFFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHATPMPYDEGPDGEGPAFRWFDRLLAGEGSGLNAPAAVIVETVQGEGGINVARS
                     EWLRALAGLCRRRDMLLIVDDIQMGCGRTGGFFSFEEAGIVPDIVTLSKSVSGYGLPMA
                     LTLLRPELDVWQPGEHNGTFRGFNPAFVTAAAALEEYWRDGRLQKQTLARGEQMEQGLA
                     ALAASRPAAVSEVRGRGLAWGVEFADPSRAAAVCARAFELGLLLETSGPRDEVVKLFPP
                     LTIEEQELEEGLALFASAVRETERPSRPAGPR"
     aSDomain        3645..4652
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EBH12_RS14330_Aminotran_3.1"
                     /evalue="1.00E-69"
                     /label="EBH12_RS14330_Aminotran_3.1"
                     /locus_tag="EBH12_RS14330"
                     /protein_end="365"
                     /protein_start="29"
                     /score="227.1"
                     /tool="antismash"
                     /translation="DRALGSRLYGEDGRPFLDFFSGAGALNYGHNNPVLKRALVDYIER
                     DGVTHALDMSTAAKRAFLETFQEVVLQPRELPYKVMFPGPAGTNAVEAALKLARKVKGR
                     EAVVFFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHATPMPYDEGPDGEGPAFRWFDRL
                     LAGEGSGLNAPAAVIVETVQGEGGINVARSEWLRALAGLCRRRDMLLIVDDIQMGCGRT
                     GGFFSFEEAGIVPDIVTLSKSVSGYGLPMALTLLRPELDVWQPGEHNGTFRGFNPAFVT
                     AAAALEEYWRDGRLQKQTLARGEQMEQGLAALAASRPAAVSEVRGRGLAWGVEFA"
     cand_cluster    4597..15583
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    4597..15583
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[9596:10583](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(9597..10583)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     gene            5001..5399
                     /locus_tag="EBH12_RS14340"
     CDS             5001..5399
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003993572.1"
                     /locus_tag="EBH12_RS14340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine synthase"
                     /protein_id="WP_114875802.1"
                     /sec_met_domain="ectoine_synt (E-value: 1.6e-47, bitscore:
                     159.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIRSLEEIEDTVRHVRAASGTWESKRLVLARDRAGFSLHVTTLY
                     AGTQTTMRYTHHVEAVLCVEGEAELTDEETGEKHWITPGTVYLLDGHERHTMRPKTDVR
                     CVCVFNPPLTGREDHDADGAYPPPGPGA"
     gene            5463..6368
                     /gene="thpD"
                     /locus_tag="EBH12_RS14345"
     CDS             5463..6368
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005477733.1"
                     /locus_tag="EBH12_RS14345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ectoine hydroxylase"
                     /protein_id="WP_114872584.1"
                     /sec_met_domain="PhyH (E-value: 3.4e-35, bitscore: 120.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTHHHRLSTDVYPTRGAAEAMMPRRDPVVWSAPAAPGPLGGAG
                     LADVDRAGFTTVEALLSPGEVALFRAELDRLVRDPAVGRDERAVVEPASRAIRSVFEVH
                     RISEVFASLVRDERVVGTARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDG
                     LPRMRAVSVSIALTGNHASNGSLMIIPGSHRTFLGCAGATPKDNYKKSLQMQDAGTPSD
                     EAVTALCEAGGIRLVTGEAGSATWFDCNCMHGSGDNITPYPRSNVFIVFNSVENTPGEP
                     FAAPARRPAFVAARDFTPVR"
     gene            6397..6747
                     /locus_tag="EBH12_RS14350"
     CDS             6397..6747
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884073.1"
                     /locus_tag="EBH12_RS14350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SAV_915 family protein"
                     /protein_id="WP_114872583.1"
                     /transl_table=11
                     /translation="MADARRDADPTPGGRPPADLLYVPVRPHRRCCVTCFFRTPGGRRT
                     AVAFTSCARLLAALGQDHPWIRLSATALRALTVPLGCTTITVDPQVAARPGASRTPRAG
                     PGRSLLPGARAN"
     gene            7681..8700
                     /locus_tag="EBH12_RS14355"
     CDS             7681..8700
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (70-171). E-value:
                     3.4e-07. Score: 21.5. Matches aSDomain:
                     nrpspksdomains_EBH12_RS14355_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014050041.1"
                     /locus_tag="EBH12_RS14355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_241563151.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.6e-14, bitscore:
                     50.6, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPPSPVTGTVLVAGGSGFIGSAVVGELAARAAAGGGPAVRVLA
                     RRAPSSRDAVVGHVRADLTRPGTLRGAMAGVEVVVHAAAYVGRDAARCEAVNHGGTLAL
                     LEEARRAGVGHVVYVSTASVYGPGPHRGADEHALAPRPASPASMSRLRAERAVLDAGGT
                     VLRPHLVYGAGDEWFIPALARLLTEVPAWPAGRASRSSLIAVGDLARGVAGLACAPSAA
                     DRSAVYHAAHPRPVAADRLLSALGRHLGFPVPRGDVPPGEHRGLVARAVPELSDHQYAL
                     LTVDHWYRAERLWSRTGEDPGPGFEARFAEAAHWYAARLAGRDRPRAGRGAGPGGRPG"
     CDS_motif       7711..7782
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EBH12_RS14355_0001"
                     /evalue="1.60E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="EBH12_RS14355"
                     /protein_end="34"
                     /protein_start="10"
                     /score="8.0"
                     /tool="antismash"
                     /translation="TVLVAGGSGFIGSAVVGELAARAA"
     aSDomain        7891..8193
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EBH12_RS14355_NAD_binding_4.1"
                     /evalue="3.40E-07"
                     /label="EBH12_RS14355_NAD_binding_4.1"
                     /locus_tag="EBH12_RS14355"
                     /protein_end="171"
                     /protein_start="70"
                     /score="21.5"
                     /tool="antismash"
                     /translation="GAMAGVEVVVHAAAYVGRDAARCEAVNHGGTLALLEEARRAGVGH
                     VVYVSTASVYGPGPHRGADEHALAPRPASPASMSRLRAERAVLDAGGTVLRPHLVY"
     gene            complement(8724..9380)
                     /locus_tag="EBH12_RS14360"
     CDS             complement(8724..9380)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387458.1"
                     /locus_tag="EBH12_RS14360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_048460798.1"
                     /transl_table=11
                     /translation="MAEQERAIRTRRTILFAAAKVFQEHGYQAATISQILAEAGVTKGA
                     LYFHFPSKEDLAQEVLLSQNQDFFVPDRPSKIQEIVDMVLLHTYRLQTDPLVQAAVRLS
                     LDELAHGVNRGESFIHWDNLLQERLEKARAQGELLPHIVPAETSGVLVGAYTGIQSLSQ
                     ALSKHQDLGTRVTALLRHLLPSIAVPSVLASVDMSQDRMLKLHADMTAQAQAQAQ"
     gene            complement(9597..10583)
                     /locus_tag="EBH12_RS14365"
     CDS             complement(9597..10583)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007387457.1"
                     /locus_tag="EBH12_RS14365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_114872582.1"
                     /sec_met_domain="AfsA (E-value: 3.6e-23, bitscore: 80.1,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSANTLRAEPATLGTQYVETDHGAAARPATPLHPSLTTTVPKEFV
                     HRAGVAEVMLTGWERADERRFAVSAQWPRGHIFFTSVNGCHDPLIAAETLRQIGSLLAH
                     AEYGVPLGHHFLMWDLSLTVRPEHLLVGGAPASLDIDVVCEDVRMRRESLAGLRYTTVM
                     RRAGQVVATGGASFTCMTSKVYQRLRADRLDGAGPQLALTAPTAPQNVGRVSPTDVVLT
                     PVGRPDRWQLRVDTRHPVLFEHPVDHIPGMMLLEAARQAAVAAVDEDAMPLSITGEFSR
                     YAELDTPCVIEARRLPRTDQGEVVQVSGRQDGEAVFCSTVTVAAPGT"
     gene            10968..13157
                     /locus_tag="EBH12_RS14370"
     CDS             10968..13157
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388089.1"
                     /locus_tag="EBH12_RS14370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 3 N-terminal
                     domain-containing protein"
                     /protein_id="WP_241563153.1"
                     /transl_table=11
                     /translation="MLCPQEAVDLDTLLPSGLGQLTRPFGTAPVDPALGALSLLRTQTG
                     ITSANRFGIPAVAHEECLAGFAAWGATAYPVPLSWGATFDPDVIRRMAAAIGRDMRAVG
                     VHQGLAPVLDVVRDARWGRVEETIGEDPYLVGTIGTAYVQGLESAGIVATLKHFVGYSA
                     SRAGRNLAPSSVGPRERADVLLPPFEMAIREGGARSVMHAYTDIDGVPSAADESLLTGL
                     LRDTWGFDGTVVADYFGIAFLKTLHGVAGDFADAAGAALTAGVDIELPTVKTFGAPLVE
                     AVTEGRVPEALIDRALRRVLTQKAELGLLDPDWSPVPPAFDGADLDDPEALRGKIDLDG
                     PENRELAREIADKAVVLLSNDGTLPLDRPRRIALVGPNATEPSAVLGCYSFPQHVGVKY
                     PDIPVGIELPDLRESLTAEFPDAEITVVRGTGVDDGDLSGIAEAVDAARDADIVVVALG
                     DRAGLFGRGTSGEGCDAESLSLPGAQQQLLDALLDSGTPVVTVLLAGRPYALGRAVQDS
                     AAIVQSFFPGVAGTRAIAGVLSGRTNPSGRLPVSVPRTPGSQPTTYLGAPLAQASEVSN
                     LDPTPAFGFGHGLTYTTFAWSDLTVDAEEAPTDGEFTASLTVRNTGERAGTEVVQLYLH
                     DPVASVVQPVQRLVGYARLDLEPGEERRVRVTVPADVASFTGRDGHRTVEPGSLELRLA
                     ASSTETRLTAEVTLTGPVRQVDHTRRFRAEFSVEA"
     gene            complement(13370..13570)
                     /locus_tag="EBH12_RS14375"
     CDS             complement(13370..13570)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131987.1"
                     /locus_tag="EBH12_RS14375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_048455106.1"
                     /transl_table=11
                     /translation="MSIEQVRDLMWIKSSYSGTNGGDCVEVAARENSVYVRDSKAVDDG
                     APVLRTDRAQWAAFVTLVSAV"
     gene            complement(13567..14424)
                     /locus_tag="EBH12_RS14380"
     CDS             complement(13567..14424)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131986.1"
                     /locus_tag="EBH12_RS14380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_048455105.1"
                     /transl_table=11
                     /translation="MGRTTQRECGTAGRRGPDQERPAAWSAYGKLVRLFRERAGLTQQA
                     LADAIGYSMEQVASVEQGRRPAKAVFTEAAERVLDAGGALRVLQPDVDRAKLPLFFQDF
                     ALLEAEAVSRFSYDPMLVPGLLQTEAYARALLEAHFPPLEEEAIEQHLTARLARQSLLT
                     RKNPCVVFSFILEEGALRRAVGGTVVLGQQLAYLLECTRRRNVEIQVMPTQLAAHSGVN
                     GQIVLLETVERRRFVSIEAQGIVNIRSDRDEVSEFWLRYGMLRSQALNSEESARLIERM
                     AGEL"
     gene            complement(14553..15290)
                     /locus_tag="EBH12_RS14385"
     CDS             complement(14553..15290)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00881"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004935208.1"
                     /locus_tag="EBH12_RS14385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitroreductase family protein"
                     /protein_id="WP_114875489.1"
                     /sec_met_domain="PF00881 (E-value: 2.3e-18, bitscore: 65.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGTPLAGALADDAAEPSLFATMSTMRAMRRLRPDPVPDELLDQ
                     LIQAAVWGPSGGNMQRYEYVVVTDRTVMAELAPLWKRCVDAYLATTGKYAPEGMDEAAY
                     GRMVAAIEYQRDHFADTPALIIPCYQFPPPRIEEEGLRIYAEALGAEATERMGRIQERF
                     SALAEGSCVYPGVQNLLLAARGLGLAANITIWHLFLETEWKAALGIPEGMNTFAVIPVG
                     WPRGNFGPVRRRPVSEVVHRDRW"
     misc_feature    15493..15506
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.86"
                     /tool="antismash"
ORIGIN
        1 ggcccgtgtc gcgagcagat ccccggggtg tccccggagt tggtcctcgg gcgcaccgcc
       61 gtgcaggaac acctcccggc cgaggagttc gtccaggacc cccggctgcg agtccgccgc
      121 gcggagcgaa cgcagtaccg tctcggtgct gtcgttctcc cagtcgatcc ttcgccgctc
      181 ctggcggaag aagtcccgcc acaccacacg gatcgcgggg tcgttctgcg agctcggctt
      241 gaacgatccg tctgcgtacc gctgcacggc cagcaggacg gcggccatgg cggcgtcgga
      301 agcctcgttg cggtacaggt cgctcttgcc gaccggaggc accgcgaagg actcggcagc
      361 ccacacgtcg cccgcgtcca tcgccgcccc ggcctggagc accgtcactc cccagtggga
      421 tgcgtcctcg gcgatcgccc agtccaaggc ggacggaccg cggtcgccgg gtggtcccgg
      481 gtgcacgatg agacaggtgt gctcccgcca cacgtcgtcc ggcagcgcgg ttttcagcat
      541 cggagcgatg atcagttctg ggcgggactc gctcactgcg gctcggacgg cttcggcgcc
      601 gtgcgcggcg agaacgacgt ccacccggtg ccctcggtcc gacagttccg cgaacacacg
      661 ctgggacaga ctgttgaacg cactggcgac gagcaagatg tccatatcgc ggcatgttcg
      721 ccggttcagg gagagtgggg aagaaccacg gcggcgtttc gccggccgcc gtcaggtcgc
      781 ttcctccatc cggatcgcat tccgcgggcc tgaccgcgcc ggccgcaacg atgacgacgg
      841 gctccctttc gggcttctgg caccatctct tccgccgccg gcgccgcacc gggaggcgct
      901 cgccgacgac ctgagcgcgt acgccggccc ggtcgcggtc accgccgaac cggccgagct
      961 ccgaccagga cccggcgacg tggctgccgc cgaccgccga gagcactgcc gctgtgtccg
     1021 gagtgggtgg gtacgaaact gcgttggagt tcgccggcgg atgcggctcc cggctacggg
     1081 ccaacaagtt gatcaccaac tacagggagt atgcaggatg atcttcgcag cgggtggcgc
     1141 aagcagcggt agcacggtcg tcagcgtcat cctgggcatt acctttctcg tcgggatcgc
     1201 actgattgtt gtggccaaga atcgcaagcg gtgagagtcg aaaacaagca gtgaaagggt
     1261 gtcccagcac ttctggcgtg ccaccagcgc gacacgtacc ggcgctgctc gttgaatgac
     1321 gccgtacaag ggccccggac tcattccgag gcccttgcgc tatttgcgcc gttgtcgcgc
     1381 agagccgcca tgaatgttgt cgacgccggg ttcatccgcg agccttcggg cacgctgaac
     1441 tccatgacga ctggggggaa gtcctaccac tgcctcaccg acgccaccgg caacgtcctc
     1501 ggcctcgccg agccggcaag cgcacccaca cctacgccta cggcctcccg cgcaccacac
     1561 ccacgcaatc cgtgccccag tcgtaccgct acgcaggagg ctacgccggt ccgaccggcc
     1621 tgtacaagat gggccaccgc tactacgacc ccaccctcgg ccgcgtcgag gcgggaatct
     1681 cggccgccgc cgagaccgga gttatcacat acgccggtgc ggttggtggt gcggtctggg
     1741 cgggagtagg cagtgctgtg ggtgttggta ctgctgtagt cggcagttgt gcactcggag
     1801 gtgccgctgg acaactacgg agcagaaaac gttacttatg ggtagggaat gacgtcatag
     1861 ctctttcccg gctccacaac tacctctcgg aacgaataca tcgcaatgaa tggttggctc
     1921 tcatgaatga tgcagcaagg ggagtgcgcg tcttttcttc gatcttgatc gtgggagggg
     1981 tgtgcgcatg tattgcagga gcattcactg gcgatgctgt gcccatcgtg ctaggcgcga
     2041 tcgccgtggt gtgcggactg gttctggcgg acttcgcctt caaggcacgt cggaagactc
     2101 gctcctgatg gaacaggggc gtggagggca tatgaagccg ctgggtcatt gagcgcacca
     2161 tggcgtggct gtccggctac cgctggctca gcccacgcta cgaacgcggt ccccgcaact
     2221 acctggctat ctcggactcg ccgctgccct gtgctgctac aaggcgactt atccacctca
     2281 ccacgtggga cacggtcggg tgtgccgcat gttcgggtgt catctgagct ggctcgccct
     2341 gtggggtggg tgggaaggat gtcgctgggc ccgagccttg tccgggtgag ttctgccaag
     2401 gcgtcgtggg ggttgcgagg acgcgggtcg ggtgtgacgg tcgggcgggt ggccaccgac
     2461 ttcggggtct atgcgatgac gttgtgggag gggatgcgtc gcgcggacat cggcctgtcc
     2521 tcgctccgtg tctgtccggt tccggctggc gttgggaggc gctccgccgg gcggtgctga
     2581 tgcgggcgcg gtcatcccgt tcggcggtcg gcggcggctg ctcctcgcgc cgcggccatc
     2641 tcggctggat gtacggagat ccggcgctaa ttgtcgcatg agatgacgtg caggggctga
     2701 gtcttcggtg ttggattgcc tggccggtgg gggggtgttg cgggttcctt tcacctttct
     2761 tcttttttaa acgggggttt tcgtgtgggc gtgtgtggct tgctgggcgt agcatcgtag
     2821 cgatgcgtcg cagcggtacg ttcgtgcgga caactgaatg ctgaagcggc agacgccgaa
     2881 gtcggtgacc cgcgcgttga gcggtcatgt ttcgggagtg cagagaacgg atcggacggg
     2941 gtctgttcac cggcgggttg gcgtttgcgc gtggtggttg gcgcagcgag agtgaggtgt
     3001 gttcggtgga cacactggtc atggcggttc ccacggtcaa ggacggggct ggggtgtggc
     3061 gtattgcccg cgggtccggg gtgctggatg tgaattcttc ttactgttat ctgttgtggt
     3121 tcagggattt cgcccgtact tccgtggtgg ctttggcgtc gggtggtgtg ccggtcgggt
     3181 tcgtcaccgg attccgccgc cccgagcagc ccgacaccct cgtcgtgtgg cagatagccg
     3241 tggacggggg gcaacggggt cggggtgcgg ccggtgcgat gctggaccat ctcaccgccc
     3301 ggcttgcggt ggacggcgcg ctgcggtttg tggagacgac catcagtgcg ggcaacgccg
     3361 cgtcgcaccg gctgttccgg tctttcgccc ggcggcacgg ggcgccgctg gtgagggatc
     3421 ttctgtttcc ggcggagttt ttccccgaca cgcatgatgc cgagttcctg taccggatcg
     3481 ggccgctgct ccgatgagcc ggcgccctcg aaacaactga gaaaacagtc cgttcctcct
     3541 cgtagggagc gagcatcatg acggttcccc atcccgcctc tcatgtgttc gagaggcttg
     3601 agtccgaggt ccgcagttat tgccggggct ggcccaccgt attcgaccgt gcactcggca
     3661 gtcgcctgta cggtgaggac ggccgtcctt ttctggattt cttctccggt gccggggcgc
     3721 tgaattacgg gcacaacaat ccggtgctca agcgtgcgct tgtcgactac atcgagcgtg
     3781 atggtgtcac gcatgctctg gatatgtcga cggccgcgaa gcgcgcgttt ttggagacgt
     3841 tccaggaggt tgtgcttcag ccgcgtgagc tgccgtacaa ggtgatgttc ccggggcctg
     3901 ccggcaccaa tgcggtggag gcggcgctga agctggcccg taaggtgaag ggcagggaag
     3961 ccgttgtctt cttcaccaat gcgttccacg gcatgtcgct gggctctctg gctgtcaccg
     4021 gtaacgcttt caagcgggcg ggcgcgggaa ttcccctggt gcacgccacc cccatgccgt
     4081 acgacgaggg gccggacggt gagggccccg cgttccgctg gtttgaccgg ctgttggcgg
     4141 gtgaggggtc cgggctgaac gctccggcgg ctgtgattgt ggagacggtg cagggtgagg
     4201 gcgggatcaa tgtggcccgc tcggagtggc tgcgcgccct ggccgggctg tgccggcggc
     4261 gggacatgct gctgatcgtc gatgacattc agatggggtg cgggcgcacg ggtgggttct
     4321 tctctttcga ggaggccggc atcgttccgg acattgtgac gctgtcgaag tccgtcagcg
     4381 gatacggact gccgatggcg ctgacgctgt tgcgtcctga gctggacgtc tggcagcccg
     4441 gcgagcacaa cggcaccttc cgtggtttca atccggcttt cgtcaccgcc gccgcggcgc
     4501 tggaggagta ctggcgtgac ggccggctgc agaagcagac cctggcccgc ggggagcaga
     4561 tggagcaggg tttggccgcg ctcgccgcgt cccggcccgc tgccgtgtcc gaggtgcgtg
     4621 gccgtgggct ggcgtggggt gtggagttcg ccgatccgtc gcgggccgcc gccgtgtgtg
     4681 cccgcgcctt cgagctgggt ttgctgctgg agacgtccgg cccgagggac gaagtggtca
     4741 agctgttccc gccgttgacc atcgaggagc aggaactgga ggaagggctc gcgctgttcg
     4801 cgtccgcggt gcgggagacc gaacggccct cgcggccggc cggcccccgt tgagcacacg
     4861 cacacgcaca cgcacacgga cacgcacacg gacacgtaca cggacacgga cacggacacg
     4921 gacacgcaca cggacatgaa cacgtacacg ggcgcgggtg tggctgtgcc cggcgacgca
     4981 cacggaaggt gggatgagtg gtgatcatcc gttcccttga ggagatcgag gacaccgtcc
     5041 ggcatgtcag ggccgcgtcc ggcacctggg agagcaaacg gctcgtcctg gcccgggacc
     5101 gggcgggttt ctccctgcac gtgacgacgc tctacgccgg tacgcagacg acgatgcgct
     5161 acacccacca cgtggaggcg gtgttgtgcg tcgagggcga ggcggagctg accgatgagg
     5221 agaccggtga gaagcactgg atcacgccgg gaacggtgta tctgctggac ggccacgagc
     5281 ggcacacgat gcggcccaag accgacgtgc gctgcgtgtg cgtgttcaac ccgccgctga
     5341 ccggccggga ggatcacgac gccgacggcg cctacccgcc gcctgggccg ggtgcctgaa
     5401 aaaagggggg gactgcgaac cgggaaaagg gatccgaaat ccgagcaggt atggggacgg
     5461 ccatgacgac gacgcaccac caccgtttga gcaccgacgt gtacccgacc cgcggcgcgg
     5521 ccgaggcgat gatgccgcgc cgcgatcccg tggtgtggtc cgcgcccgcc gcgcccggcc
     5581 ctctgggagg ggccggactg gcggatgtcg accgcgccgg cttcacgacc gtcgaggcgc
     5641 tgctgagccc cggcgaggtg gccctgttcc gcgccgagct ggacaggctg gtgcgtgacc
     5701 cggcagttgg ccgcgacgaa cgcgccgtcg tggagcccgc ttcccgtgcc atccggtcgg
     5761 tgttcgaagt gcaccggatc agtgaggtgt tcgcctcgct cgtgcgggac gaacgcgtgg
     5821 tgggaacggc ccgtcagatc ctcggctcgg acgtgtacgt gcaccagtcc cgcatcaacg
     5881 tcaaacccgg tttcggggcg agcggcttct actggcactc cgacttcgag acctggcacg
     5941 ccgaggacgg cctgccccgc atgcgcgccg tgtcggtgtc gatcgcgctc accggcaacc
     6001 acgccagcaa cggaagcctg atgatcatcc ccggctcgca caggacgttc ctgggctgcg
     6061 cgggcgccac cccgaaggac aactacaaga agtccctgca gatgcaggac gcggggacgc
     6121 cgtcggacga ggccgtcacc gcgctgtgcg aggcgggcgg catccggctg gtcaccggcg
     6181 aggccggttc ggcgacctgg ttcgactgca actgcatgca cggctccggc gacaacatca
     6241 cgccgtaccc gcgcagcaac gtgttcatcg tgttcaacag cgtcgagaac accccgggcg
     6301 agcccttcgc ggcaccggcc cgccggcccg cgttcgtcgc ggcgcgtgac ttcaccccgg
     6361 tgaggtgacg gccgcaaggc gtgagcggag accaccatgg ctgatgcccg gcgcgacgcg
     6421 gaccccacgc ccggtggacg tccgccggcc gacctgctgt acgtgcccgt ccggccgcac
     6481 cgtcgctgct gtgtgacgtg cttcttccgc acccccggcg gccgccgtac cgccgtcgcc
     6541 ttcacctcct gcgcacggct gctggcggcc ttgggccagg accacccgtg gatcaggctc
     6601 tccgccaccg cgctccgcgc cctcaccgtc cccctggggt gcaccacgat caccgtcgat
     6661 ccgcaggtgg cggcccgccc gggcgcctcc cgcacacccc gtgcgggccc cggcaggagc
     6721 ctgctgccgg gggcccgggc gaactgagac ggacccccgc cggcgccggc cacgggcccg
     6781 cggactcacc cgcgtccctg aagggaaggt gcccttcagg gccatgggtc tgcccgatcc
     6841 ggcggagcac ccccggcgcc gccgccgcgt gctgccgcgg ccggcggaaa gcgcacgtac
     6901 gcgccggccg cggcagatgc ccgggcgagc gggtgagacg cggcggacgc acaacggccc
     6961 cggcgggcgg ccgcacgaac acgctgtcct ccaccgcaag ggtgcggcac ccccggcagc
     7021 ggtgtggccg gctgtccgcc ggcggccgcg ctcctcccct ccggcgtggc cgcagctctc
     7081 gcgccggccc gccgcaggag ggcgggggga acaggggggt gcggacaccc gcgtggtgtc
     7141 gtcggcgggg ctgtgcgccg cgcggctcgg ctctacggct gcggctcttc accgcagaac
     7201 gcccctgcgg ggtttccgcc cgggcccggc tgtgtggtgt gtccggtgtg tcggcgtgtg
     7261 tgtcgagggc cgtctgtccg cgcgtcaggg cttgagcggg gtttccgccc gggcccggcc
     7321 gtggcgtgtg tccggtgtgt cggcgtgtgt gtcgagggcc gtctgtccgc gcgtcagggc
     7381 ttgagcgggg tttccgcccg ggcccggccg tggcgtgtcc agcgtgtcgg cgtgtgcgcc
     7441 gagggccatc cctccgcgcg tcagggcctg gcccgtgccg cggacaccgg cggccctgac
     7501 cgtccgcttg cggcggcggg cacgccgggc ggccaggcgc cgtgtaggcc cggccgctcg
     7561 gcatacccgc ccccgtccgc ccacaccggc cctccaaaga accgtccagc cggtatattc
     7621 tgccctggtg cgggccggcc cgcctcggtg tcgccgttcg agcgaagtgg ggaaagcatc
     7681 gtgtcgagtc cgccctcacc tgtcacgggc accgtcctgg tcgccggcgg cagcggcttc
     7741 atcgggagcg cggtggtcgg tgaactggcc gcgcgtgccg ccgctggcgg cgggcccgcg
     7801 gtgcgggtcc tggcgcgccg ggcgccgtcg tcgcgtgacg ccgtggtggg gcatgtgcgc
     7861 gccgacctga cccggcccgg gacgctgcgc ggagcaatgg cgggggtgga ggtagtggtg
     7921 cacgccgccg cctacgtggg gcgtgatgcc gcccgctgcg aggcggtcaa ccacggcggc
     7981 accctggccc tgctggagga ggcccggcgc gcgggtgtcg ggcacgtcgt ctatgtcagc
     8041 acggcctccg tctacggtcc ggggccgcac cgcggcgcgg acgagcacgc actggcgccg
     8101 cgccccgcct ccccggcgag catgtcacgg ctgcgggcgg agcgggccgt gctcgacgcg
     8161 ggcggcaccg tgctgcgccc gcacctggtg tacggcgcgg gcgacgagtg gttcatcccc
     8221 gccctggccc ggctcctcac cgaggtgccg gcgtggccgg ccggccgcgc ctcgcgcagt
     8281 tccctgatcg cggtgggtga tctggcgcgc ggtgtggcgg gtctggcgtg cgcgcccagc
     8341 gccgcggacc gctccgcggt gtaccacgcg gcccaccccc ggccggtggc ggcggaccgg
     8401 ctgctgtcgg cgcttgggcg ccacctcggg ttccccgtgc cccgcgggga cgtgccgccc
     8461 ggggagcacc gcggcctcgt cgcgcgtgcg gtgcccgaac tctccgacca ccagtacgcc
     8521 ttgctcaccg tggaccactg gtaccgtgcc gagcgtctgt ggtcgcggac cggcgaggat
     8581 ccgggaccgg gcttcgaggc ccgtttcgcc gaggcggcgc actggtacgc ggctcgtctc
     8641 gccggccggg accggccccg ggcggggcgg ggagccgggc cgggcggccg gccgggctga
     8701 gccgccggcc gcggccgggc gggctactgg gcctgggcct gggcctgggc cgtcatgtcg
     8761 gcgtgcagct tcagcatgcg gtcctggctc atgtccaccg aggccaggac ggaggggacc
     8821 gcgatgctgg gcagcaggtg gcgcagcagg gcggtgaccc tcgtgccgag gtcctggtgc
     8881 ttgctgagcg cctgggagag ggactggatg cctgtgtagg cgccgacgag gacgcccgag
     8941 gtctcggccg gcacgatgtg ggggagcagc tcgccctggg cccgggcctt ttccagccgt
     9001 tcctggagca ggttgtccca gtggatgaac gactcgccgc ggttgacgcc gtgggccagc
     9061 tcgtccaggg acagccgcac ggccgcctgg accagggggt cggtctgcag gcggtaggtg
     9121 tgcagcagca ccatgtccac gatctcctgg atcttggacg ggcggtccgg cacgaagaag
     9181 tcctggttct gggagaggag cacctcctgg gccaggtcct ccttggaggg gaagtggaag
     9241 tagagcgcgc ccttggtgac gccggcctcc gcgaggatct gggagatcgt cgccgcctgg
     9301 tacccgtgct cctggaagac cttggccgcg gcgaacagga tcgtcctgcg tgtgcggatg
     9361 gcccgctctt gctcagccat gggtgtcctc cagtcgttcc acgtgcccgg gcgtaccccc
     9421 gattgcaaac catccagtct gtattttaac agcctgtctc cgtctgccgg tgatggccgt
     9481 cgtccgggcg ggggagaccc cggccggagt cgtgccggcc gggtcgcgga cacacgtgcg
     9541 ggccggccgg aaggcgccgt ccgcgccctt ccggccggcc cgcggccgtg gcggggtcag
     9601 gtgccgggcg ccgccacggt cacggtggag cagaagaccg cctccccgtc ctgacggccg
     9661 ctcacctgga cgacttcccc ctgatccgtg cgcgggaggc ggcgggcctc gatcacgcag
     9721 ggcgtgtcca gctcggcgta gcggctgaac tccccggtga tggacagggg catggcgtcc
     9781 tcgtcgacgg ccgccaccgc ggcctgccgg gcggcctcga gcagcatcat gcccggtatg
     9841 tggtccaccg ggtgctcgaa gaggacgggg tggcgggtgt ccacccgcag ctgccagcgg
     9901 tccggccggc ccacgggtgt caggacgacg tccgtcggcg agacgcggcc gacgttctgg
     9961 ggcgccgtcg gggcggtgag ggcgagctgg gggccggcgc cgtccagccg gtcggcacgc
    10021 agccgctggt agaccttgga cgtcatgcag gtgaaggaag cgccgccggt cgccaccacc
    10081 tgcccggcgc ggcgcatcac cgtcgtgtag cgcagcccgg ccaggctctc ccggcgcatc
    10141 ctgacgtcct cgcagacgac gtcgatgtcg agggaggccg gcgcgccgcc gacgaggagg
    10201 tgttcgggcc gcaccgtgag cgacaggtcc cacatcagga agtggtgacc gagcggaacc
    10261 ccgtactccg cgtgggccag cagtgaaccg atctggcgga gcgtctccgc cgcgatcagc
    10321 gggtcgtggc agccgttcac gctggtgaag aagatgtggc cgcgaggcca ctgggcgctc
    10381 acggcgaacc ggcgctcgtc cgcgcgctcc cagccggtga gcatgacctc ggcgacgccg
    10441 gcgcgatgga cgaactcctt ggggacggtg gtggtcagag acggatggag cggtgtggcg
    10501 ggtctcgccg ccgccccgtg atcggtttcc acgtactggg tgccgagtgt cgcgggctcg
    10561 gcgcggagcg tgttcgcaga catcgcttgt tcccccttgg ccgcgtggtg cggaggtttt
    10621 gtgtgggtcg ctcaggccga gaagatacat accagccggt ttaatttcta gcggtatgag
    10681 ggactccgct gtccgggttt tccggagtga tctataccgt tttgccggcc gcccgcttcg
    10741 gcggccgaag agggcgctcc gggccggctc ccttcccgcg ggcgggtggt ccggaaggcg
    10801 tccgcggcgt gccgggggaa ttgcggtgac ggcccgtccg gccgtgcggg ccccggcggg
    10861 gaacgccggt tcctcaaggg gttcccgagg ggttcccggg cgttttcccg gtgccgtgga
    10921 cggcggttcg cgcgggagcg ggcgacggga gcgcgcggct gccccgggtg ctctgtccgc
    10981 aggaggccgt cgacctcgac acgctccttc cgtccggcct gggccagctc acccgcccct
    11041 tcggcaccgc ccccgtcgac ccggcgctcg gcgcgctctc cctgctgcgc acccagaccg
    11101 gcatcacctc ggcgaaccgc ttcggcatcc ccgccgtcgc gcacgaggag tgcctggccg
    11161 gcttcgccgc ctggggcgcc accgcctacc ccgtcccgct gtcctggggc gccaccttcg
    11221 acccggacgt gatccgccgg atggccgccg ccatcggccg tgacatgcgc gccgtcggcg
    11281 tccaccaggg cctcgccccc gtcctggacg tcgtccgcga cgcccgctgg ggccgcgtcg
    11341 aggagaccat cggcgaggac ccgtacctcg tcggcaccat cggcaccgcc tacgtgcagg
    11401 gccttgagtc cgccgggatc gtcgccaccc tcaagcactt cgtcggctac tcggcctcgc
    11461 gcgcgggacg caacctcgcc ccctcctccg tggggccgcg cgagcgtgcc gacgtgctgc
    11521 tcccgccgtt cgagatggcg atccgcgagg gcggcgcgcg ttccgtcatg cacgcctaca
    11581 ccgacatcga cggagttccc tccgcggccg acgagagcct gctcaccggg ctgctccggg
    11641 acacgtgggg cttcgacggc acggtcgtcg ccgactactt cggcatcgcg ttcctcaaga
    11701 cgctgcacgg ggtcgcgggc gacttcgccg acgcggccgg cgccgcgctc acggcgggcg
    11761 tcgacatcga actgcccacg gtcaagacgt tcggcgcccc gctcgtggag gccgtcaccg
    11821 agggccgggt gccggaggcc ctgatcgacc gcgccctgcg gcgtgttctg acccagaagg
    11881 cggagctggg cctgctcgac cccgactgga gcccggtgcc gcccgcgttc gacggcgccg
    11941 acctggacga ccccgaggcc ctgcgcggca agatcgacct cgacggtccc gagaaccgcg
    12001 aactggcccg ggagatcgcc gacaaggcgg tcgtcctgct cagcaacgac ggcaccctgc
    12061 cgctggaccg cccccgccgg atcgcgctcg tcggccccaa cgccaccgaa ccgtccgccg
    12121 tcctgggctg ttactcgttc ccgcagcacg tgggcgtgaa gtacccggac atccccgtcg
    12181 gcatcgaact gcccgacctg cgcgagagct tgacggccga gttccccgac gccgagatca
    12241 ccgtcgtccg cggcaccggc gtcgacgacg gggacctctc cggcatcgcg gaggccgtgg
    12301 acgcggcgcg tgacgccgac atcgtcgtcg tggcgctcgg tgaccgcgcc ggcctgttcg
    12361 gccgcggcac cagcggtgag ggctgcgacg cggagtcgct gtcgctgccg ggcgcccagc
    12421 agcagctgct ggacgcgctg ctggactccg gcaccccggt ggtgacggtc ctgctcgcgg
    12481 gccgccccta cgcgctcggc cgcgcggtgc aggactcggc ggcgatcgtg cagtcgttct
    12541 tcccgggcgt cgcgggcacc cgcgccatcg ccggggtgct cagcggacgt acgaacccct
    12601 ccggccgcct gccggtcagc gtcccgcgca cccccggctc ccagccgacc acgtacctgg
    12661 gcgccccgct cgcccaggcc agcgaggtgt ccaacctcga cccgacgccg gccttcggct
    12721 tcggacacgg gctgacctac acgacgttcg cgtggagcga cttgaccgtg gacgccgaag
    12781 aggcgccgac ggacggggag ttcaccgcct ccctcaccgt gcgcaacacg ggggagcggg
    12841 ccggcacgga ggtcgtccag ctctacctgc acgacccggt cgcctccgtg gtccagccgg
    12901 tccagcgcct ggtcggctac gcccgcctgg acctggagcc gggcgaggag cgcagggtgc
    12961 gcgtcacggt cccggcggac gtggcgtcct tcaccggccg cgacggtcac cggaccgtcg
    13021 aaccgggttc cctggaactc cgcctggcgg cgtccagcac ggagacccgc ctgacggcgg
    13081 aggtcaccct gacgggcccg gtacggcagg tggaccacac gcggcggttc cgtgcggagt
    13141 tctcggtgga ggcctgacgc cgccaccccc ttgcggagac cacaccggcc cggaccgcac
    13201 gagcggtccg ggccggtgca ccatgggcgc gcccggcatc aacctctccc cacgccgcac
    13261 gaatcgacgt gaacgggctc gcggtgagcc ggaacccgtc agcggaacgc gtcggcgttc
    13321 tcctggtcga cggtgatccc gaacgccagg acctcaagca ggcccgaggt caaaccgcgg
    13381 acacgagcgt cacgaacgcc gcccactgcg cgcggtccgt ccgcagtacg ggcgcgccgt
    13441 cgtccacggc cttggagtcc cgtacgtaca cggagttctc acgggcggcg acctcgacgc
    13501 agtcgccgcc gttggttccg ctgtagctgc tcttgatcca catgaggtcg cgaacctgct
    13561 cgatgctcat agctcccctg ccatgcgctc gatcaaccgg gcagactcct cggagttgag
    13621 ggcctgtgaa cgcagcattc catagcgtag ccagaactcg ctgacctcgt cccggtccga
    13681 ccggatgttc acgatgccct gggcctcgat agagacgaac cgccgccgtt cgacggtctc
    13741 cagcaggacg atctgcccgt tcaccccgct gtgcgcggcc agttgggtgg gcatcacctg
    13801 gatctccacg ttgcgcctgc gggtgcactc caacaggtat gcgagttgct gccccaggac
    13861 cacggtgccg cccaccgccc ggcggagagc gccctcctcg aggatgaacg agaacacgac
    13921 gcacgggttc ttacgcgtca gcagggactg ccgggccagc cgcgcggtga ggtgttgctc
    13981 gatggcctct tcctcaaggg gagggaagtg ggcctcgagc aaggcgcgtg catacgcctc
    14041 cgtctgcaac aaccccggca ccagcatcgg gtcgtacgag aagcggctca ccgcctccgc
    14101 ctccaagagg gcgaagtcct ggaagaacag gggaagtttc gcccggtcca cgtccggctg
    14161 gagcacccgt agcgccccgc ccgcgtccag gacgcgttcc gccgcctccg tgaagaccgc
    14221 cttcgccggg cggcggccct gttcgacgga ggcgacctgt tccatcgagt agccgatggc
    14281 gtccgcgagg gcctgctggg tgagccccgc gcgctcacgg aagaggcgga ccagcttgcc
    14341 gtacgcgctc cacgccgccg gacgctcctg gtcgggcccg cgccggccgg ccgtaccgca
    14401 ctcccgctgg gtcgtcctgc ccatcgagcc ccctgctccg tcgcacagtg atccgtcgtg
    14461 gagcacaacg gccgagacgc ccttgcggcc acggcgggca gccgtacggc ggccgtacag
    14521 ctgcgtacgc ccgccgtacc gcgtcgtacg tcctaccacc ggtcccggtg gacgacctcc
    14581 gagaccggcc ggcgccggac cggcccgaag ttgccccgcg gccaccccac cggaatcacc
    14641 gcgaacgtgt tcatgccctc ggggatgccg agcgccgcct tccactccgt ctcgaggaac
    14701 aggtgccaga tggtgatgtt ggccgcaagg cccagcccgc gcgcggcgag cagcaggttc
    14761 tgtacgccgg ggtagacgca ggacccctcc gcgagggcgg agaaccgctc ctggatgcgg
    14821 cccatccgct ccgtcgcctc cgcgcccagc gcctcggcgt agatccgcag accctcctcc
    14881 tcgatccgcg gcggggggaa ctggtagcac gggatgatca gcgccggggt gtcggcgaag
    14941 tggtcgcgct ggtactcgat cgcggcgacc atgcgcccgt acgccgcctc gtccatgccc
    15001 tcgggggcgt acttgccggt cgtcgccagg tacgcgtcca cgcaccgctt ccacagcggc
    15061 gccagctcgg ccatgaccgt ccggtcggtg acgacgacgt actcgtagcg ctgcatgttg
    15121 ccgccgctgg ggccccacac ggccgcctgt atcagctggt cgagcagctc gtccggcacc
    15181 gggtcggggc gcaggcggcg catcgcccgc atcgtggaca tggtcgcgaa gagggacggc
    15241 tcggcggcgt cgtcggccag ggccccggcg agaggggttc cagttgtcat gatcgggagt
    15301 gtagggactg tgaacttccc gtagggcggc tctacttgaa tgtgggaccg tcggtcccgc
    15361 atttcccgcg catgacgtcc cgcccggcgc ggtactcggt ccgcactgtg gaagggagcg
    15421 gatcatggcg atctgtgaag tgtgcgggaa cgactacgcc ctctccttcg aggtgcgcac
    15481 ggtcgacgat tccgtccata cgttcgacag catcgagtgt gccgcccaca agatggcgcc
    15541 catctgcgac aactgcggct gcaaggtgct cggccacggt ctt
//
