LOCUS       NZ_CP033054            26378 bp    DNA     circular CON 14-APR-2024
DEFINITION  Bacillus velezensis strain Bac57 chromosome, complete genome.
ACCESSION   NZ_CP033054
VERSION     NZ_CP033054.1
KEYWORDS    RefSeq.
SOURCE      Bacillus velezensis
  ORGANISM  Bacillus velezensis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
            Bacillus amyloliquefaciens group.
REFERENCE   1  (bases 1 to 4226250)
  AUTHORS   Othoum,G., Prigent,S., Derouiche,A., Shi,L., Bokhari,A.,
            Alamoudi,S., Bougouffa,S., Gao,X., Hoehndorf,R., Arold,S.T.,
            Gojobori,T., Hirt,H., Lafi,F., Nielsen,J., Bajic,V.B., Mijakovic,I.
            and Essack,M.
  TITLE     Comparative genomics study reveals Red Sea Bacilli with
            characteristics associated with potential microbial cell factories
            (MCFs)
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4226250)
  AUTHORS   Othoum,G., Bokhari,A., Alamoudi,S., Bougouffa,S., Goa,X.,
            Hoehndorf,R., Arold,S.T., Gojobori,T., Hirt,H., Lafi,F., Bajic,V.B.,
            Mijakovic,I. and Essack,M.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2018) Computational Bioscience Research Center,
            King Abdullah University of Science and Technology, King Abdullah
            University of Science and Technology (KAUST), Thuwal, Makkah
            23955-6900, Saudi Arabia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera Assembler v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 344X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003667745.1-RS_2024_04_14
            Annotation Date                   :: 04/14/2024 18:37:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,235
            CDSs (total)                      :: 4,117
            Genes (coding)                    :: 4,019
            CDSs (with protein)               :: 4,019
            Genes (RNA)                       :: 118
            rRNAs                             :: 9, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 9, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 98
            CDSs (without protein)            :: 98
            Pseudo Genes (ambiguous residues) :: 0 of 98
            Pseudo Genes (frameshifted)       :: 60 of 98
            Pseudo Genes (incomplete)         :: 53 of 98
            Pseudo Genes (internal stop)      :: 14 of 98
            Pseudo Genes (multiple problems)  :: 25 of 98
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:15:58
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3701286
            Orig. end                         :: 3727664
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP033054.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26378
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="13"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..26378
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26378
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16378](-)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16378)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    33..47
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.56"
                     /tool="antismash"
     CDS             95..241
                     /gene="allorf_3701381_3701527"
                     /locus_tag="allorf_3701381_3701527"
                     /protein_id="allorf_3701381_3701527"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLKLYTLYVFFHVIPLTMRMFLQSLPIARISCRIIFFINCKKYDI
                     LSA"
     CDS_motif       95..178
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLKLYTLYVFFHVIPLTMRMFLQSLPIA"
                     /locus_tag="allorf_3701381_3701527_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       179..241
                     /prepeptide="core"
                     /locus_tag="allorf_3701381_3701527_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.60"
                     /molecular_weight="2367.9"
                     /monoisotopic_mass="2366.3"
                     /core_sequence="RISCRIIFFINCKKYDILSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLKLYTLYVFFHVIPLTMRMFLQSLPIA"
                     /leader_location="[94:178](+)"
     misc_feature    101..119
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: medium, score: 29.41"
                     /tool="antismash"
     CDS             complement(127..210)
                     /gene="allorf_3701413_3701496"
                     /locus_tag="allorf_3701413_3701496"
                     /protein_id="allorf_3701413_3701496"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MMKKMMRQDMRAIGSDCKNIRIVSGIT"
     CDS_motif       complement(166..210)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MMKKMMRQDMRAIGS"
                     /locus_tag="allorf_3701413_3701496_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(127..165)
                     /prepeptide="core"
                     /locus_tag="allorf_3701413_3701496_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.80"
                     /molecular_weight="1282.5"
                     /monoisotopic_mass="1281.7"
                     /core_sequence="DCKNIRIVSGIT"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MMKKMMRQDMRAIGS"
                     /leader_location="[165:210](-)"
                     /alternative_weights="1300.5"
     gene            267..824
                     /locus_tag="D9777_RS18800"
     CDS             267..824
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391264.1"
                     /locus_tag="D9777_RS18800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="WP_021494142.1"
                     /transl_table=11
                     /translation="MEKNALDIIGHAEEHLIERIAENMHTFGMPATLGRVLGIIYMNRK
                     PMTLNELSEATGMSKTRMSQVVREMTDANLAEKVFEKGVRKDLYDVEHDYYQTFISLFT
                     ANWTKAVSKNKMLYKKLNRELTELLESENLSPDIEEKARQLLDELTDWLHYYDWLSRLI
                     EFFESEEVFQHVPKIEKSSTRR"
     gene            complement(847..1479)
                     /locus_tag="D9777_RS18805"
     CDS             complement(847..1479)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014471043.1"
                     /locus_tag="D9777_RS18805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAAT family transporter"
                     /protein_id="WP_007409973.1"
                     /transl_table=11
                     /translation="MFSFIIHVFISLFAVSNPIGNVPIFLSLTEGYSEKERTAIARKAS
                     VLSFIILAAFLIFGHLIFKLFDINIHALRIAGGIFIFGIAYNLLNAKKSHVQSLHHEEK
                     GESKEKADISVTPLSIPIIAGPGTIATVMSLSAGHGGIFHYISVLIGIAAVIAMTFIFF
                     HYSSFISNKLGKTEMNVITRLMGLILAVVAIGMIGAGLKGMFPILVS"
     gene            complement(1656..2806)
                     /locus_tag="D9777_RS18810"
     CDS             complement(join(1656..2533,2533..2806))
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1026: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="D9777_RS18810"
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /protein_id="WP_099721935.1"
                     /ribosomal_slippage=""
                     /transl_table=11
                     /translation="MGTRVSYPVEVKQKAVEMRLAGVPMKEIMQELNIKNKTQVQTWVR
                     WHKTGDTHRFEQPVGKQYTYGKGPEYSSELEKLQAENRYLRQQNEVFKKVQRIGKEADS
                     ETPVELVEALRGTMTIQDICIHLGISRASYYRWKKNLMKDNPKYHLEKQIGTLCREHKF
                     RYGYRKITAILKKGMRVNHKTVQRIMQKNQWQCRVKVKKRKKDGQPYAVAENILDRNFQ
                     SERPLEKLVTDITYLPYGQKQLYLSSILDLYNGEVIAFTIGDRQDTDFVLHTLDQLPAL
                     PENCVLHSDQGSVYTSYEYQKAVKTKGITMSMSRKGTPADNASIESFHSSLKSETFYLN
                     SIDRTTTTIVERTAIEYIHYYNNIRIQTKLNSQSPIQYRQLAV"
     gene            3207..3917
                     /locus_tag="D9777_RS18815"
     CDS             3207..3917
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007409971.1"
                     /locus_tag="D9777_RS18815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_014418906.1"
                     /transl_table=11
                     /translation="MYCSQCGHHTDGGKFCEKCGAPQPGQGGAGQTQGQAAQAGAAAKQ
                     ASKQFALFVLDVLKRPYQTCKTTGGEQLVSSIINMVLFCLVTPIMFYILLSDGFRDVSF
                     TAVVIKPALTFALCVFCLYLLIFIALKAGGAQVSFKDSLSRFGAFLIPFTAILLLALIF
                     MLLHTTVCFTILAVGLLGAAFAVPPLMLASYQHQLTTKADIIYSVIVIYLIICVTFQFT
                     IKHYIKELMNYFFF"
     gene            complement(3959..5737)
                     /locus_tag="D9777_RS18820"
     CDS             complement(3959..5737)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014305844.1"
                     /locus_tag="D9777_RS18820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_021495212.1"
                     /transl_table=11
                     /translation="MFFCKYCGQQNNEEAHFCKECGKPIGKGSRLERQAAESASQPRKP
                     IPKKTLFLWGGIAAALILLIAAYKTGAWLTSEKRLTDQFEQAVHDGDTKKLAALLTPSD
                     KKLKLNETNVKPLLAYAKKHDELLASLRGNSSEKDAVYVKKEGKTLLLFDHYELKVDPV
                     YFRVTSNYKGADLYINSEKTGTVKKADETQIFGPYAPGVYTAEAKLKNETVDVVKKQEA
                     EAAGSRNVEFDLPLDAEDVTFTPADSFKSVKGDLLINGKSVHKDPFTSVTYGPLLTDGS
                     MTAAVEADFPWGKMKTADVPINSTDVDLTLIPDQDTQQTIMDTIVKTTKQYTKAMADGN
                     TDQMTEAGSAWKEQTKEAVSGMKSSGTFLKDQYKETSFDLDSFAISQENGRWQVTVTGK
                     ELHESAYFDGNTKPDMEEAEPSFHYVLSYDTKHKKWVFEKADPASDSSGTNVKKIKNDQ
                     PNTYTSAWASSKGNTASGSVTNEQVTSFMTDYLTNQSSAVSLNNFAIMAGNLEEGSPLY
                     ADQQKLVKKLHSEGTTEVFNEVNVKSFSQKGSHLTIHTYEEFYITKAGGSPKLRTYNWT
                     YGGVVKDGRIYLTSIQ"
     misc_feature    complement(5821..5834)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.2"
                     /tool="antismash"
     gene            5869..6330
                     /locus_tag="D9777_RS18825"
     CDS             5869..6330
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151638.1"
                     /locus_tag="D9777_RS18825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_021495213.1"
                     /transl_table=11
                     /translation="MQKLSIRKAAEPDEALYELLLLADPSKEIVDDYLVRGECYTAWTS
                     DELAGVFVLLKTRPKTVEIVNIAVKESMHNNGIGRKLIEEAVNKAKQMGAATIEIGTGN
                     SSIGQLALYQKCGFRLQAIDHDFFIRHYEEEIFENGIQCRDMIRLYLDL"
     gene            complement(<6529..7330)
                     /locus_tag="D9777_RS21860"
                     /pseudo=""
     CDS             complement(<6529..7330)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611387.1"
                     /locus_tag="D9777_RS21860"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRVSDPVEVKQKV"
     misc_feature    complement(7550..7563)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.22"
                     /tool="antismash"
     gene            complement(7645..7815)
                     /locus_tag="D9777_RS21575"
     CDS             complement(7645..7815)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D9777_RS21575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_155238646.1"
                     /transl_table=11
                     /translation="MKNYKGDGAVFLVIGFCLGLFLGVVFDILPYGLSIGILIGSLIDL
                     YFYARYKNNNK"
     gene            complement(7839..10004)
                     /locus_tag="D9777_RS18830"
     CDS             complement(7839..10004)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="D9777_RS18830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_021495216.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.9e-37, bitscore:
                     124.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVKKKKRVPIVKQLQQTECGLCCCAMLIRFYNSNETLFELRSFL
                     EAGRDGLTIKQLKNLLVHKGFKADIYKSTILGLKKINVPFIAYWNNEHFIVVEKIKENY
                     YYIIDPANGRRKLTEEEFKKGFSSYILYAVPSESFTPNKRKDKNVWFGVLKNITNYKLL
                     FSIIVFLSLISYLLTLYVPILVQKLIDTSIEYNNLNSISNIVWITFLISILYGMFVLFR
                     GLKMISLNIFLSKNLVVDTFAHLLKLPFKFFDLRSPGDLLFRLNSMNGFRELLSTQLIS
                     GLIDLGAVVFILAYMFFKSIPLTLITILIFAINTIFMFLTRPAVAQAIDDEVAEQSKSQ
                     AIQIESIFSIAAIKISGMENEIFSTWNNSFNEVIKRFKKRSILQNVVNTVTQVFQTIAP
                     LVILILELLLFFDNKFTMGEVIAYHSLSVTFFGLTTALFGTYTQFILATSYLERVKDIT
                     ETECEKNIENAVNLKLRGNVKLENVSFSYTKHSPKVLKNISLEIREGQKIAIVGSSGSG
                     KSTLSKLIMGLYDPTEGQICFDSIPLEKLDRKQLYKQMGIVPQDITLFNSSILKNITLN
                     NKNISIEKVRKVAKAAQIDKEIESMPMKYNTPISEMGMNLSGGQRQRIVLARALLNDPK
                     ILILDEATSSLDLVNETLISKYLSEMGCTRVVIAHRLSTIMDSDFIIVLDKGEVVEVGK
                     HEELIALEGVYSNLYRSQTKKQKTYSS"
     gene            complement(10001..12964)
                     /locus_tag="D9777_RS18835"
     CDS             complement(10001..12964)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="D9777_RS18835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_021495217.1"
                     /sec_met_domain="DUF4135 (E-value: 1.4e-87, bitscore:
                     292.2, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.2e-59, bitscore:
                     199.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDISYENNNFIRDAVINFSSPTNEVEKLRIKNKDYFGNFYTFFLD
                     FYQQKLVNTLENASKENNLKLNKHKIISSALEAFSQELIQLCIRTLIVDINERKENGLL
                     EGKDSRLRYKNYNNLIFKSEYVAGILNKYPVLTYLISSRISNKILYLKEVLENLRKNRQ
                     DIYRELKIEFDEVSNIYFSSGDTHNGGKNVLIIETNQGKIVYKPHSLSPDILFNSIVDY
                     VNNSDKILKKIYKIRTLNYKDYGYQEFIDYKECETSEKLNFYFYRVGVSLSIFHIIGCD
                     DLHHENLIAHGEYPVVIDLETLIKNNSMYKPRNNNLIDNFHEDINYSVLGTMLLPLNLQ
                     TSIFDFDLGGISNDENQTSEIWKSYIIDFEGTDEIQLTKKSVIMNSTQNRAAYNGKAAD
                     PKDYIEEILKGFTDCYNFVLENKSGFYDLVKTVGSSNLEVRQVLRATSIYARFLEASTH
                     PNYLSSFEERKELFKKINIAEGVTDKFSKKNLNELESLMCNDVPYFSTMYNSLDLICNK
                     STSIVNFFRECLLDVVLNKIKSISKTSLKKQQYYIRMSLTTTIKDSWKRTNKHNKKYRP
                     KLFGNNNKNYLECATEIGDLFLETAIWNNDRSKCTWVTPIISENNKVKLGPLNFNLYEG
                     GGVILFLALLGKETGNKEYFDLAFAGMRGIEELFLSDDKMDGRLSLFTGIGSLAYIYYH
                     LYTYTNDYKYYEKFKKYINKINEMNISGDIPLDIVGGVSSLIVFLLNLYKETKLDILNS
                     VCCKLGNTLYQCLEKNGKYNYLTGLSHGYSGFTWALCYLGHITKDEKYTTLGKELLKRE
                     NKFFDLNTSNWKDLREGEGNSDPVYWCHGAGGIALSRAFLKNLLKNKENVVDKEVDKEV
                     DKEVDKDLNCAISKLLSDGFKKTTDHSLCHGIFGNIDILLKLSELLNDIDLQEVAFKEA
                     QNAINYIRNKGFIPGLQDHFDLNTFMLGLGGVGYSLLRLHNPVNPSLLAMEVRSYNE"
     gene            complement(13033..13242)
                     /locus_tag="D9777_RS18840"
     CDS             complement(13033..13242)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF038161.1"
                     /locus_tag="D9777_RS18840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class II lanthipeptide, LchA2/BrtA2 family"
                     /protein_id="WP_021495218.1"
                     /transl_table=11
                     /translation="MKKDMVKKVSGFIEEDELISLANGDNATGGATPATVVLTATIGLT
                     GTTFTVTLSAASCPTSACTKQCNK"
     CDS_motif       complement(13153..13242)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MKKDMVKKVSGFIEEDELISLANGDNATGG"
                     /locus_tag="D9777_RS18840_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13033..13152)
                     /prepeptide="core"
                     /locus_tag="D9777_RS18840_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.10"
                     /molecular_weight="3579.1"
                     /monoisotopic_mass="3576.9"
                     /core_sequence="ATPATVVLTATIGLTGTTFTVTLSAASCPTSACTKQCNK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKDMVKKVSGFIEEDELISLANGDNATGG"
                     /leader_location="[13152:13242](-)"
                     /alternative_weights="3597.1"
                     /alternative_weights="3615.2"
                     /alternative_weights="3633.2"
                     /alternative_weights="3651.2"
                     /alternative_weights="3669.2"
                     /alternative_weights="3687.2"
                     /alternative_weights="3705.3"
                     /alternative_weights="3723.3"
                     /alternative_weights="3741.3"
                     /alternative_weights="3759.3"
                     /alternative_weights="3777.3"
     gene            complement(13292..16378)
                     /locus_tag="D9777_RS18845"
     CDS             complement(13292..16378)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="D9777_RS18845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_021495219.1"
                     /sec_met_domain="DUF4135 (E-value: 1.2e-96, bitscore:
                     322.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.1e-67, bitscore:
                     226.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTNKYNLQYWMKMFPEVNNKDELQKIFLNVSGKTIQSLIRDDTN
                     IEQNKSIIDIDRVLDHKKSDFLVRNSEEFLEHNPFFHFFSPFLNCKIEEFLVKVRIEDA
                     VDNEDEFVKKVIKHIMDLMFEKAFRVLVLEVNIARLEGNLEGTTPEERLNHFLVVSLND
                     ESFLKSVYKEYEVLTSLLCVTIDDYFTYVMEIIKNTKREISSLNSKFNSDNDLGAITNI
                     TTGLGDTHQKGKSVSTIYFKSGKKIIYKPRDLTLEQGFQEVLYWLGEKNIPGILNFKRV
                     QIHTVNDSGWMEHIDYKSCFNKNEANDFYTRSGNLLCLLYLLNAVDFHHENLIAHGSFP
                     VLVDLESLFHARLKVDQIDKKSAVVKATELVDNSVQSISLLPTKISKRVGDKDISLDIG
                     GLAAYKEQLSPHKSLVIENAGTDTIKILRKNTFIKPQLNNPSIKTGSYLYSENYTGQIK
                     DGFASLYSWVMLNKDEFWDKISQTFKETNSRFIFRPTYLYTQLLRISSHPDFMRDTYRR
                     KIILHRIGIDYIQEYKDILNSEYKDLLTGDVPFFRSSIEHEHLIDSRGKRIHSILEEPP
                     IKTVKQKIFNLSKEDLKRQIDFIEMSYISNEKRLKEVTDIKFSKAASLNKIKSENWIDE
                     ATQIGEFIVENSVCGINKKQKDRMWIGPSLEGIEEDIWNANVLGFDIYNGNSGIALFLG
                     YLGEILNRKDFKQAAIETMRPIQKFISEIKEDHPYLIGAFQGISGYFYTLNKLSNLFGD
                     SELRKTSLENIGVLSKLGKFDKVYDLIGGSLGSLAVMLSIIPDITEENNKKEILKISHT
                     HCEHILSVAKNFEEQISWPGKFSAAYSGFSHGNSGFIAYLYKYFKLTNDEKLLEVIQRA
                     LRFERRLYSEDHNNWYTTENKDKLANGWCHGAPGILLSKLILKDNGFEDEYIEKEISTA
                     IDSSIRNGIGNNPTYCHGDLGVLSILNYASDLTNNINLKNRCLRTYQDLFENVLTKKWR
                     KRDLVCTRSYSLMIGLSGIGYSMIKNYAPEIVPNFLWLE"
     gene            complement(16451..16681)
                     /locus_tag="D9777_RS18850"
     CDS             complement(16451..16681)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_ha"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884148.1"
                     /locus_tag="D9777_RS18850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_021495220.1"
                     /sec_met_domain="mature_ha (E-value: 5.3e-07, bitscore:
                     27.2, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGAFNTWNT
                     TTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
     CDS_motif       complement(16565..16681)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /locus_tag="D9777_RS18850_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(16451..16564)
                     /prepeptide="core"
                     /locus_tag="D9777_RS18850_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-3.20"
                     /molecular_weight="3669.1"
                     /monoisotopic_mass="3666.9"
                     /core_sequence="FNTWNTTTTSLGGILVSEVLGNKGKVCTGTKECQGTC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKTKILKTPELKVTKDLNLIDPCGDVLEEIKEHEVSGA"
                     /leader_location="[16564:16681](-)"
                     /alternative_weights="3687.1"
                     /alternative_weights="3705.2"
                     /alternative_weights="3723.2"
                     /alternative_weights="3741.2"
                     /alternative_weights="3759.2"
                     /alternative_weights="3777.2"
                     /alternative_weights="3795.3"
     misc_feature    16938..16951
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.53"
                     /tool="antismash"
     misc_feature    16964..16976
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    complement(17739..17754)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.73"
                     /tool="antismash"
     gene            complement(18064..19356)
                     /gene="eno"
                     /locus_tag="D9777_RS18860"
     CDS             complement(18064..19356)
                     /EC_number="4.2.1.11"
                     /GO_function="GO:0004634 - phosphopyruvate hydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="eno"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391270.1"
                     /locus_tag="D9777_RS18860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopyruvate hydratase"
                     /protein_id="WP_007409956.1"
                     /transl_table=11
                     /translation="MPYIVDVYAREVLDSRGNPTVEVEVYTETGAFGRALVPSGASTGE
                     YEAVELRDGDKDRYLGKGVLTAVNNVNEIISPELLGFDVTEQNAIDQLLIELDGTENKG
                     KLGANAILGVSMACARAAADFLQIPLYQYLGGFNSKTLPVPMMNIVNGGEHADNNVDIQ
                     EFMIMPVGAPNFREALRMGAQIFHSLKSVLSAKGMNTAVGDEGGFAPNLGSNEEALQTI
                     VEAIEKAGFKPGEEVKLAMDAASSEFYNKEDGKYHLSGEGVVKTSAEMVDWYEEMVSKY
                     PIISIEDGLDENDWEGHKLLTERLGKKVQLVGDDLFVTNTKKLAEGIKNGVGNSILIKV
                     NQIGTLTETFDAIEMAKRAGYTAVISHRSGETEDSTIADIAVATNAGQIKTGAPSRTDR
                     VAKYNQLLRIEDQLAETAQYHGINSFYNLNK"
     gene            complement(19384..20919)
                     /gene="gpmI"
                     /locus_tag="D9777_RS18865"
     CDS             complement(19384..20919)
                     /EC_number="5.4.2.12"
                     /codon_start=1
                     /gene="gpmI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391271.1"
                     /locus_tag="D9777_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="WP_003151620.1"
                     /transl_table=11
                     /translation="MSKKPAALIILDGFGLRNETVGNAVAQAKKPNFDRYWNQYPHQTL
                     TASGEAVGLPEGQMGNSEVGHLNIGAGRIVYQSLTRVNVAIREGEFERNQTFLDAIKNA
                     KDNDKALHLFGLLSDGGVHSHINHLFALLKLAKSEGLTKVYIHGFLDGRDVGPQTAKTY
                     IQQLNEQIEEIGVGEIASISGRYYSMDRDKRWDRVEKAYRAMAYGEGPSYRSAMDVVDD
                     SYANGIHDEFVIPSVITKENGEPVAKIHDGDSVIFYNFRPDRAIQISNTFTNKDFRDFD
                     RGENHPKNLYFVCLTHFSESVDGYVAFKPVNLDNTVGEVLAQHGLKQLRIAETEKYPHV
                     TFFMSGGREEEFPGEERILINSPKVATYDLKPEMSAYEVKDALVKEIAADKHDAIILNF
                     ANPDMVGHSGMVEPTIKAIEAVDECLGEVVDAIIAKGGHAIITADHGNADILITETGEP
                     HTAHTTNPVPVIVTKEGVTLREGGILGDLAPTLLDLLGVEKPKEMTGTSLIQK"
     gene            complement(20912..21673)
                     /gene="tpiA"
                     /locus_tag="D9777_RS18870"
     CDS             complement(20912..21673)
                     /EC_number="5.3.1.1"
                     /GO_function="GO:0004807 - triose-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="tpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391272.1"
                     /locus_tag="D9777_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="triose-phosphate isomerase"
                     /protein_id="WP_003151618.1"
                     /transl_table=11
                     /translation="MRKPIIAGNWKMNKTLGEAVSFVEEVKSSIPAADKAEAVVCAPAL
                     FLEKLTSAVKGTDLKVGAQNMHFEENGAFTGEISPVALKDLGVDYCVIGHSERREMFAE
                     TDETVNKKAHAAFKHGIVPIICVGETLEEREAGKTNDLVADQVKKGLAGLSEEQVAASV
                     IAYEPIWAIGTGKSSTAKDANDVCAHIRKVVAESFSQETADKLRIQYGGSVKPANIKEY
                     MAESDIDGALVGGASLEPQSFVQLLEEGQYE"
     gene            complement(21699..22883)
                     /locus_tag="D9777_RS18875"
     CDS             complement(21699..22883)
                     /EC_number="2.7.2.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004618 - phosphoglycerate kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /function="3-phosphoglycerate kinase"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391273.1"
                     /locus_tag="D9777_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglycerate kinase"
                     /protein_id="WP_014418909.1"
                     /transl_table=11
                     /translation="MNKKTVKDIDVKGKVVFCRVDFNVPMKDGEVTDDTRIRAALPTIK
                     HLADQGAKVLLASHLGRPKGEVVEELRLTPVAARLGELLGKEVKKADEAYGDAVKAQIS
                     DMKDGDVLVLENVRFYPGEEKNDPELAKAFAELADVYVNDAFGAAHRAHASTAGIAEHL
                     PAVAGFLMEKELDVLGKAVTNPERPFTAIIGGAKVKDKIGVIESLLDKVDNLIIGGGLA
                     YTFVKALGYEVGKSLLEEDKIELAKSFMDRAKEKGVTFYMPEDVLVADDFSNDANVQIV
                     PISEIPSDLEAIDIGTKTRETYAEVIKNSKLVVWNGPMGVFEIDLFAQGTKAVAEALAE
                     ANDTYSVIGGGDSAAAVEKFGLADKMSHISTGGGASLEFMEGKELPGVAALNDK"
     CDS             complement(22948..23178)
                     /gene="allorf_3724234_3724464"
                     /locus_tag="allorf_3724234_3724464"
                     /protein_id="allorf_3724234_3724464"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGLLQNVRVLKFP
                     RHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
     CDS_motif       complement(23074..23178)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /locus_tag="allorf_3724234_3724464_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(22948..23073)
                     /prepeptide="core"
                     /locus_tag="allorf_3724234_3724464_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.70"
                     /molecular_weight="4707.5"
                     /monoisotopic_mass="4704.6"
                     /core_sequence="LQNVRVLKFPRHFRFLSRLPWLRRRSAPCPEAAICPAAEAS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MVLSDRNAIMKADKGRGRTPFPFFHENRLSESAGL"
                     /leader_location="[23073:23178](-)"
                     /alternative_weights="4725.5"
     misc_feature    complement(23126..23135)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.98"
                     /tool="antismash"
     gene            complement(23205..24212)
                     /gene="gap"
                     /locus_tag="D9777_RS18885"
     CDS             complement(23205..24212)
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391274.1"
                     /locus_tag="D9777_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_003151611.1"
                     /transl_table=11
                     /translation="MAVKVGINGFGRIGRNVFRAALNNPEVEVVAVNDLTDANMLAHLL
                     QYDSVHGKLDAEVKVDGSNLVVNGKTIEVSAERDPAKLSWGKQGVEIVVESTGFFTKRA
                     DAAKHLEAGAKKVIISAPANEEDITIVMGVNEDKYDAANHHVISNASCTTNCLAPFAKV
                     LNDKFGIKRGMMTTVHSYTNDQQILDLPHKDYRRARAAAENIIPTSTGAAKAVSLVLPE
                     LKGKLNGGAMRVPTPNVSLVDLVAELNKDVTAEDVNAALKEAAEGDLKGILGYSEEPLV
                     SGDYNGNANSSTIDALSTMVMEGSMVKVISWYDNESGYSNRVVDLAAYIAKQGL"
     gene            complement(24246..25280)
                     /gene="cggR"
                     /locus_tag="D9777_RS18890"
     CDS             complement(24246..25280)
                     /codon_start=1
                     /gene="cggR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003151607.1"
                     /locus_tag="D9777_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gapA transcriptional regulator CggR"
                     /protein_id="WP_003151607.1"
                     /transl_table=11
                     /translation="MNQLIQAQKKLLPDLLLVMQKRFEILQYIRLTEPIGRRSLAASLG
                     LTERVLRSEVQFLKEQNLIDIKTNGMTMTEEGYSLLSILEDTMKDVLGLTLLEKTLKER
                     LNLKDAIIVSGDSDQSPWVKKELGRAAVACMKKRFSGKNIVAVTGGTTIEAVADMMTPD
                     SKNRELLFVPARGGLGEDVKNQANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEP
                     SVKEVLHTIKSASMLVHGIGEARTMAERRNTPLEDLKKIDDNHAVTEAFGYYFNADGEV
                     VHKVHSVGMQLDDLDAIPDIIAVAGGSSKAEAIEAYFKKQRNTVLVTDEGAAKKLLRDN
                     SPSI"
     misc_feature    25376..25389
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.01"
                     /tool="antismash"
     misc_feature    complement(25468..25486)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 23.66"
                     /tool="antismash"
     misc_feature    complement(25596..25610)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(25890..25906)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.87"
                     /tool="antismash"
     misc_feature    26359..26374
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.14"
                     /tool="antismash"
ORIGIN
        1 cagcaatccg tgcacctccg aagggttccg ttatttttct gaaaagtata atctttatta
       61 taagatgaaa tttgtaaaat aaaaagttta caatgtgttg aaattatata cattatacgt
      121 attttttcat gttatcccgc tgacaatgcg gatgttctta caatcgctcc cgatagctcg
      181 catatcctgc cgcatcatct ttttcatcaa ctgtaaaaaa tatgatatat tgtcagcatg
      241 aaaagccagt gaagggatga tcagccgtgg aaaaaaacgc tcttgatatc atcgggcatg
      301 ctgaagagca tctcattgag agaatcgccg agaatatgca tacattcgga atgccggcca
      361 cacttggacg tgtgctcggt attatttata tgaaccgcaa gccgatgacg ttaaatgagc
      421 tgtcagaggc gaccgggatg agcaaaacga ggatgagcca ggtggtccgc gaaatgaccg
      481 atgccaatct ggctgaaaaa gtgtttgaaa aaggcgttcg gaaagacctt tacgacgtcg
      541 agcatgatta ttaccagacg tttatctccc tgtttacggc aaattggaca aaggcggtca
      601 gcaaaaacaa aatgctctat aaaaagctga accgcgagct gactgagctt ctggaatcgg
      661 aaaatctcag tcccgatatt gaagaaaaag cccgccagct tttggatgaa ctgacggatt
      721 ggctccatta ttatgactgg ctgagccgtt tgatagaatt ttttgagagt gaagaagtgt
      781 ttcagcatgt gccgaaaata gaaaaaagca gcacccgaag ataaccgggc gctgcttttt
      841 tttaagtcag gaaaccaata tcgggaacat gcctttcaga ccggcgccta tcatgccgat
      901 cgccaccacc gccaaaatca gccccatcag tcgggtaatg acgttcattt cggttttccc
      961 gagcttattg ctgatgaaag aagaatagtg aaagaagatg aacgtcatcg cgatgacggc
     1021 cgcaatgccg ataagcacgc tgatgtaatg gaagatgccg ccatggccgg ccgacagact
     1081 catcaccgtc gcgatcgtac cgggaccggc gataatcgga atcgacaaag gcgtcacgga
     1141 tatatcggct ttctccttgc tctccccttt ctcttcatga tggagagact gtacatgaga
     1201 tttcttcgcg ttcagaagat tataagcgat gccgaaaata aaaatgccgc ccgcaatacg
     1261 taaggcatga atgttaatgt caaacagttt aaagatcaga tggccgaaga ttaaaaaagc
     1321 cgccaagatg ataaacgaca gaacggaagc cttgcgcgcg atcgctgtcc gttctttctc
     1381 cgagtaccct tccgtcagtg aaagaaaaat cggcacgttt ccgatgggat tggagactgc
     1441 aaacagtgaa atgaagacat gaatgatgaa tgaaaacatg cgtacctcct tatggcttgc
     1501 cgttattgag ttatgttttg ttctccgctg tttcttatgc atggttttta ccccggggtc
     1561 tgctttttat aacctcagcc ggacgatccg gaaacagaaa aaaaccgtcc ttgtagggac
     1621 tggcccctgt ttttgagaca gggatcaaaa caccttcata cagccaattg ccgatattgt
     1681 atcggcgatt ggctgtttag tttcgtttga atacgaatat tgttataata atgaatgtat
     1741 tctatggcag tgcgttctac gatggtcgtc gtagttcgat caatgctgtt aagatagaac
     1801 gtttcagact ttagtgagga atgaaacgat tcgatggagg cattatcagc gggcgtccct
     1861 ttgcgggaca tgctcatggt aatgcctttt gttttaacag ctttctgata ctcataagat
     1921 gtataaacag aaccttggtc actatgtaac acgcagttct ctggcagtgc gggcagctga
     1981 tcaagtgtgt gtaagacaaa gtctgtgtcc tgtctatcgc caattgtaaa agcaatcact
     2041 tctccattgt ataaatccaa tatactggaa agatacaatt gtttctgccc ataaggcaaa
     2101 tatgtgatat ccgttactag cttttccaga gggcgttcag actgaaagtt tcgatccaat
     2161 atattctcgg ccacggcata tggctgccca tctttcttgc gctttttcac cttaacccgg
     2221 cattgccact gattcttctg cataatgcgc tgaaccgttt tatgattcac acgcattccc
     2281 ttttttaata tggctgtgat tttccgatag ccatatcgaa acttgtgttc tcggcacaac
     2341 gtgccgattt gtttttctaa atggtattta gggttatctt tcatcagatt cttcttccaa
     2401 cgataataag atgctcgtga gatacctaaa tgaatacaga tatcctgtat ggtcattgtg
     2461 ccgcgcaatg cttctacaag ctcgactggc gtttcgctat cagcttcctt tccaattcgt
     2521 tgcacttttt taaaacttca ttctgttgtc tcagataacg attttctgcc tgcagtttct
     2581 ctaattcgga agaatactcc gggccttttc cgtaagtgta ttgctttccg acaggctgtt
     2641 cgaatcgatg tgtatcccca gtcttatgcc atctaaccca tgtctgaacc tgtgtcttat
     2701 tcttaatatt caattcctgc atgatctctt tcataggcac gcctgccaat ctcatttcta
     2761 cagccttctg tttcacttca accggataac tcactcttgt ccccatagaa aaaacacctc
     2821 caagtctaat ttcggctaac aatcatccgt tttcaaactt gaaggtgttt tttgtttgtc
     2881 tcatcttatg gggtcagtcc ctgtaaggac ggtttttttg tttgctatct ccataagcct
     2941 tttccgaatt tcaacagccg ataaagcatt ttcaattttt ttagcatgcg ttaatttcct
     3001 ttttcactct gaatcaatgc gccgagagac atgatatcta tcagctccat taaaattcta
     3061 ccataatggg tactttttct ctattatcaa ttcatagaga aagtgatttg tatatcttta
     3121 gaaaactccg ttacatccgc cctattttct tttataatgt aaatattgaa caaaatccct
     3181 atattacttg taaaaggagt tttagaatgt attgttctca atgcggccat catactgatg
     3241 gcggaaagtt ttgtgaaaag tgcggggcgc cccagcccgg gcagggaggc gcaggccaaa
     3301 cgcaaggcca ggccgctcag gccggcgccg cggctaagca ggcttcaaag caatttgcct
     3361 tattcgtgct tgatgtgtta aagagaccgt accaaacatg taaaacgaca ggcggcgaac
     3421 agcttgtcag cagcatcatc aacatggtgc ttttctgcct ggtgacgccg attatgtttt
     3481 atattctcct atcagacggc tttcgtgacg tcagttttac cgcggttgtg atcaaaccgg
     3541 cgcttacctt tgcattatgc gttttctgcc tgtatctctt gatttttatc gctttgaagg
     3601 ccggcggcgc gcaggtgtca tttaaagatt cgctgtccag attcggggcc tttttgattc
     3661 cgtttacagc tattttgctt cttgccctca tttttatgct gcttcataca accgtttgct
     3721 tcaccattct ggctgtcggt cttttaggag cggcgtttgc cgtgcctccg ctcatgctgg
     3781 cgagctatca gcatcagctc actactaagg cggatatcat ttattctgtt atcgtcatct
     3841 atttgatcat ttgcgtaacg tttcaattca cgatcaagca ttatataaaa gaactcatga
     3901 attatttctt cttttaaaaa cggaaacccc cgccgcctga ttggcgcggg ggtttttttt
     3961 attgaatgga tgttaaataa attcttccgt ctttaacaac gccgccatac gtccaattgt
     4021 atgttctgag cttcggactg ccgccggctt tcgtaatata aaactcctcg tacgtgtgaa
     4081 tcgtcaaatg ggagcctttc tgtgaaaagc ttttgacatt cacttcatta aatacttcgg
     4141 tcgtcccctc gctgtgcagt tttttgacca gtttctgctg atcagcatac aaagggctcc
     4201 cctcttctaa attgcccgcc atgatggcaa aattgttaag gctgacggcg cttgattgat
     4261 ttgtcaggta atcagtcata aacgatgtga cttgctcgtt tgtcacgctg cctgaagctg
     4321 tatttccttt ggatgatgcc catgcggatg tataggtatt cggctggtca ttttttattt
     4381 tttttacatt tgtcccggaa gaatctgagg caggatcagc tttttcgaaa acccattttt
     4441 tatgttttgt atcatatgag agtacatagt gaaaactcgg ctcagcctct tccatatcag
     4501 gcttcgtatt cccgtcgaaa taagcagact catgaagctc tttacccgta acagttactt
     4561 gccagcggcc gttctcttga gaaatcgcaa atgaatccag atcaaagctt gtctctttat
     4621 actgatcctt caaaaaggtg ccggaactct tcatgccgga taccgcttct ttcgtctgct
     4681 ctttccaggc ggaaccagcc tcggtcatct gatcagtatt tccgtctgcc atcgcttttg
     4741 tatactgctt cgttgttttg acaatcgtgt ccatgattgt ttgttgtgta tcttgatccg
     4801 ggataagcgt taagtccaca tcagtactgt tgatcggaac atcggcagtt ttcattttcc
     4861 cccaaggaaa atcagcctcc acggcggctg tcatggaacc gtcagttaag agcggaccgt
     4921 atgtaacgga tgtaaacgga tctttatgga cggacttgcc gtttatcagc agatcgcctt
     4981 tcacgctttt gaagctgtct gccggagtga acgtcacatc ctcggcgtct aacggcaggt
     5041 caaactcaac attccggctg ccggccgcct ctgcctcttg ctttttgaca acgtcaaccg
     5101 tctcattttt aagcttggct tccgccgtgt agacaccggg tgcatacggg ccgaagattt
     5161 gggtttcatc ggcttttttg accgtacctg ttttctcgct gttgatataa agatcggcgc
     5221 ctttataatt gcttgtgacg cggaaataaa ccggatcgac tttcagttcg taatggtcaa
     5281 acaaaagaag ggtttttccc tcttttttga cgtataccgc atctttttct gatgaattgc
     5341 cgcgaagcga tgccagcagt tcatcgtgtt tctttgcgta tgcaaggagc ggtttgacat
     5401 tggtctcatt cagcttcagt tttttgtctg aaggagtgag cagggctgcg agctttttcg
     5461 tgtccccgtc atgaaccgcc tgttcgaatt gatctgtgag ccttttttca gatgtcagcc
     5521 aggctccggt tttatatgcg gcaatcaata agatcagcgc tgcggcaatg cctccccata
     5581 ggaagagcgt ttttttaggg atcggctttc tcggctgtga tgcggattca gccgcctgcc
     5641 gctccagccg gcttcctttc ccgatcggtt ttccgcattc tttacagaaa tgcgcctctt
     5701 cgttgttctg ctggccgcaa tacttacaaa aaaacatgac tttcctccta ttcaatctgc
     5761 aaaacttgta taacttttcc tatgtttcat attttataat aaagtagaat gattttggag
     5821 ttattttgaa aaatagctgt cgatcataac ggaggaggag aaacggacat gcaaaaactg
     5881 agcatccgaa aagccgcgga gccggatgaa gcgctgtatg aactattgct gctggccgat
     5941 ccgtcgaaag agattgtcga tgattatctt gtaagaggag aatgctatac ggcttggacg
     6001 tcagacgagc ttgcaggggt cttcgtcctt ttgaaaacaa gaccaaaaac agtagaaatc
     6061 gtcaatattg cggtgaaaga atcaatgcac aacaatggca tcggcagaaa gctcatagaa
     6121 gaggccgtga ataaggcaaa acaaatggga gcggcgacta ttgaaattgg aacgggcaac
     6181 tccagtatag gccagcttgc cctttaccaa aaatgcggct tcagacttca agccatcgac
     6241 catgattttt tcatcaggca ttatgaagag gagattttcg aaaacgggat acagtgccgg
     6301 gatatgatac ggctttattt ggacctttaa taaaagaact gccaatgatg cgattaaacc
     6361 ccgttttcga gacagggata aaaacacttt taaacagcca attgccgctc gtctatcaat
     6421 gattggctgt ttagttcgtt tgaatacgaa tattgttatt ataaatgtaa tcgttgacag
     6481 tgcattctac gatgacgggc gtggttttgt tttaacagct tttctgacac tatgcaacac
     6541 gcagctctca ggcaaaattg gcagctgatc aagtgtgtgt cctgtttatc tccaatcgta
     6601 aaagcattca cttctccatt gtatacttcc aatatcgcga acagatacaa ttattctgac
     6661 tataaggaaa attcgggaag tctgttacta ttttttcaag agggagatca ggctgaaagt
     6721 tccatattat cagttgcggc ataaatatgc tcatttttct tgcatcctta atccggtact
     6781 gctactgatt tttctgaatg atacgctgaa acgttttatg gttaacacgc atttcctttt
     6841 ttattaggga agtgatgatc caatagccct atcgataccc atgctttcgg cataatgcgc
     6901 caatgtgttt ttccaaatgc cctttgcact gattcttctt cacatttttc tttcagagac
     6961 aataagacgc tcgtgagata cctaaaagat cacagatatc tgcaaaacct tctacaagtc
     7021 cgactgaagt ttggctttta acttcctttc taattcgttg tactctttta acacttcatt
     7081 cggctgtcgc aaataacgat tctctgcctg cagtctctgg ttcggaagta aaccccagac
     7141 catttccgta agtatattgc ttttcaacag gctgttcgaa tgtatatccc cagctttatg
     7201 ctatctaatc caagtctgca cgtccgtgta ttcttaatat ttaatttctg catcatctct
     7261 ttcatcggca cgcctgccaa tctcatgtct acaccttctg tttgacttca accggatcac
     7321 ttactcttat tccatagaaa aaacacctcc aagtctaata ccggataaca gtcatccgtt
     7381 ttcaaacttg aaagtgtttt tttttggctc atcttatagg tcagtccctt tgttttttct
     7441 aaagacataa agttgcaatc ttttgttggt aggaacatca agtaatagat taaaacttaa
     7501 taatccataa aactcttatg ttctttatac cattctaatt ttaaattcat taaaataatt
     7561 ttaaagttta acacaaattt ctcagttgct gcccaaagga ataaaatctc ctcattgatc
     7621 ttgatgttta agatataatt atacttattt attattattt ttgtatctag cataaaaata
     7681 aaggtcaatt aacgatccaa tcaatattcc tatggaaaga ccatacggta aaatatcaaa
     7741 aacaactcct aaaaaaagac ctaaacaaaa acctattact agaaataccg ctccatctcc
     7801 tttatagttt ttcaaatcaa acaactcctt aatagtgatt atgatgaata tgttttttgt
     7861 tttttcgttt gtgaacgata tagattacta tatacccctt ctaaagcaat cagttcttca
     7921 tgtttaccaa cctccaccac ttcaccttta tctaggacaa ttataaaatc cgaatccata
     7981 attgttgaca atctatgcgc gataaccact cttgtgcatc ccatttcact taaatattta
     8041 gaaatcaatg tttcattcac caaatctaat gaacttgtag cctcatctaa aattaaaatt
     8101 ttagggtcat ttaaaagtgc tctggctagt acaatccttt gtcgctggcc acctgataaa
     8161 ttcataccca tttctgaaat aggtgtatta tatttcattg gcatactttc aatttcttta
     8221 tctatttgtg ctgctttcgc tacttttctc actttttcta tactaatatt tttattattc
     8281 aatgtgatat ttttcagtat agaactatta aacaaggtaa tatcctgggg tacaattccc
     8341 atttgtttgt ataactgttt tctatctaat ttttcaagag ggatactatc aaaacaaatt
     8401 tgtccttcag tcggatcata aagccccatt attaacttac taagtgtact tttaccagaa
     8461 ccagatgaac ctactatagc aattttctgc ccttctctta tttccaaaga aatattctta
     8521 agcacctttg gagaatgttt agtataagaa aaagagacgt tttcaagctt tacatttcct
     8581 cttaatttaa ggtttactgc attttcaata tttttttcac attcagtctc tgtaatatct
     8641 ttaactcttt ctaagtaaga agtagctaag ataaactgag tataagtacc aaataaagca
     8701 gttgttaatc caaaaaaagt aacagataaa gaatgatatg cgataacctc tcccattgta
     8761 aatttattat caaaaaataa tagcagttct aatattaaaa taaccaaggg agcaattgtt
     8821 tgaaaaacct gagttactgt attaactaca ttttgtaaaa tggatctttt tttgaatcgc
     8881 tttattactt cattaaaact gttattccaa gttgagaaaa tttcattttc cattcccgaa
     8941 attttaatgg ctgcgataga aaaaatagac tcgatttgaa tggcttgaga tttactttgc
     9001 tcagctactt catcatcgat ggcctgcgcg acagcaggtc tagtcaaaaa catgaatata
     9061 gtgttaattg caaatattaa tattgttatc aaggttaatg gtatagattt aaagaacata
     9121 tacgctaaaa taaaaactac cgctcctaaa tcaattaggc cagaaattag ttgagttgat
     9181 aaaagctctc tgaatccatt catgctattt aacctaaata acaagtcacc aggtgatcta
     9241 agatcaaaga atttaaaagg aagttttaga agatgagcaa atgtatcaac aacaagattt
     9301 ttactaagga atatattgag gcttatcatt ttgagccctc taaacaaaac aaacattcca
     9361 tacaatattg atattaaaaa tgttatccaa acaatattac ttattgaatt taaattatta
     9421 tactcaatac ttgtatctat aagcttctgt accaaaatag gtacatacaa cgtcaataaa
     9481 taacttatta gagataaaaa tactataata gaaaataaca atttatagtt tgtaatattt
     9541 tttaatacac caaaccatac attcttatct tttcgtttat tgggagtgaa actttctgaa
     9601 ggaactgcat ataaaatata ggacgagaaa cctttcttaa actcttcttc tgttaatttt
     9661 cttcgtccat tagccggatc tataatataa taataatttt cctttatttt ttcaacgact
     9721 ataaaatgtt cattattcca atatgcaata aaaggaacat taattttttt taaccctaga
     9781 atagtggatt tatatatatc cgccttaaat cctttatgaa ctaataagtt ttttaactgc
     9841 ttaatagtaa gtccgtctct tccagcctcc aaaaatgacc ttaactcaaa aagagtttcg
     9901 ttactgttat aaaaacggat caacatagca caacagcaaa gtccacattc agtttgttgc
     9961 aattgtttta caataggtac tctctttttt ttcttcacta tcattcattg taactcctta
    10021 cttccattgc taacaatgaa ggattgacag gattgtgtaa ccttaataag ctgtagccta
    10081 cgcctccaag tcccagcata aatgtattta aatcaaaatg atcctgtaaa cctggaataa
    10141 aacctttatt tctaatataa ttaattgcat tttgagcttc tttaaatgct acttcctgaa
    10201 gatcaatatc attgagaagt tcacttaatt tcaataatat atctatatta ccaaaaatac
    10261 catgacataa gctatgatca gttgtttttt taaatccatc ggaaaggagc ttgcttatag
    10321 cgcaatttaa atctttatca acttctttat caacttcttt atcaacttct ttatcaacta
    10381 cgttctcttt gttctttaac agatttttta aaaaagctct tgatagagct atacctcccg
    10441 caccatgaca ccaatatact ggatcagagt tcccctctcc ttctcttaaa tccttccaat
    10501 tagaggtatt caaatcaaaa aacttatttt ctcttttcaa taactctttt cctaaagttg
    10561 tgtatttttc gtctttagta atgtgaccca gataacaaag agcccacgta aaaccagaat
    10621 atccatgtga aagtcctgtt agataattat atttaccatt cttttctaag cattgatata
    10681 aagtattacc tagtttacaa cacacggagt ttaaaatatc taatttagtt tccttatata
    10741 ggtttaataa aaaaacaata agactagata ctccccctac aatatccaat ggtatatctc
    10801 ctgaaatatt catttcattt attttattaa tatatttttt aaatttttca tagtatttat
    10861 aatcatttgt ataagtgtat aggtggtaat atatataggc taaggaacct atccctgtaa
    10921 ataatgataa ccggccatcc atcttatcat cactcaaaaa aagttcttca atacctctca
    10981 ttcctgcaaa ggctaaatca aagtactctt tattaccagt ttcttttcca agtaaagcta
    11041 agaataatat tactcctcca ccttcatata agttaaagtt caatggaccc aattttactt
    11101 tattattctc agatattata ggtgttaccc aagtacattt gcttctatca ttattccata
    11161 ttgctgtttc taaaaataag tctcctattt ctgttgcgca ctctaaataa tttttattat
    11221 tatttccaaa taatttagga cgatatttct tattgtgttt gtttgttctt ttccaactgt
    11281 cttttatagt tgtagtaagt gacattcgaa tataatattg ctgttttttt aaacttgttt
    11341 tacttatact tttaattttg tttaatacaa catcaagtaa acactctcta aaaaaattta
    11401 ctatacttgt acttttatta caaatcaaat ccaaagaatt atacattgtt gaaaaatacg
    11461 gaacatcatt acacattaaa gattccaact catttaaatt cttcttgcta aatttatctg
    11521 ttactccttc cgcaatattt atttttttaa ataattcctt tctttcctca aaactagata
    11581 aataatttgg atgagtggaa gcttctaaaa accttgcata tatactggta gctcttaaaa
    11641 cttgccttac ttccaggttg ctgcttccta ctgtttttac caaatcataa aaaccacttt
    11701 tattttctaa aacaaaatta taacaatctg taaaaccttt taatatttct tcaatataat
    11761 ctttagggtc tgcggctttc ccattatatg cagctctgtt ttgagtactg ttcattatta
    11821 ctgatttttt agttaactga atttcatcag ttccttcgaa atctataata tacgatttcc
    11881 atatttctga tgtttgattt tcatcatttg atattccgcc aaggtcaaaa tcaaatatag
    11941 aagtttgtaa atttaatggg agaagcatag tgccaagaac tgagtaatta atatcctcat
    12001 gaaaattatc aattaaatta ttatttcttg gtttatacat agaattattt tttatcagag
    12061 tctccaagtc aataacaaca ggatattcgc catgtgcaat taagttttca tgatgcaaat
    12121 catcgcatcc tataatgtga aaaatagata aacttacacc tactctataa aaatagaagt
    12181 tcagtttttc ggaagtctca cattctttat aatcaataaa ctcttgatag ccatagtctt
    12241 tataattaag cgttctaatt ttataaattt tttttagaat tttatctgaa ttattaacat
    12301 agtcaactat actattaaat aagatatcag gagataaact atgcggctta tatacaattt
    12361 tcccttggtt tgtttcaatt attaagacat ttttccctcc attatgagtg tctccgctgc
    12421 taaaataaat attggagact tcatcaaatt caatttttag ttctctataa atgtcttgac
    12481 gattttttct taaattctct agaacttctt tcaagtacaa gattttattt gatattctac
    12541 tagaaattaa ataggttaaa acaggatact tattcaaaat tccagccaca tattcactct
    12601 taaaaattaa attattataa ttcttatagc gtaaccttga atcttttcct tctaataaac
    12661 cattttcttt tctttcatta atatcaacga ttaaagttct tatacataac tgaattaatt
    12721 cctggctaaa agcctctaac gcactactta taattttatg tttgttaagt tttaaattat
    12781 tttccttact tgcgttttct aaagtattaa ctaatttttg ttgataaaaa tctaaaaaga
    12841 atgtataaaa gttgccaaag taatctttgt tttttattct taatttttct acttcgtttg
    12901 tcggcgaact gaaattaatt acagcatctc tgatgaaatt attgttttca tagctaatat
    12961 ccatttataa cctctccaaa agatttaata gagaattgtt tgttaaaaca attctctatt
    13021 aacacattat gtttatttgt tacactgttt tgtacacgct gatgttggac atgatgctgc
    13081 acttaaagta actgtaaaag tcgttccagt gagtccaata gttgcagtta aaacgactgt
    13141 tgctggagta gctcctccag tagcattatc accattagct aacgatataa gttcgtcttc
    13201 ttcaataaaa cctgaaacct ttttgaccat atctttcttc ataattctct cacctccttt
    13261 caagtatgac tttgaataag agtattaaag cttattctaa ccataaaaaa ttgggaacaa
    13321 tttccggagc ataatttttg atcattgagt aacctattcc tgataatccg atcattaaac
    13381 tatatgatct agtacagact aagtctctct ttctccattt cttggtcaaa acattttcaa
    13441 ataggtcttg ataagttctt aaacatctat tcttcaaatt aatattgtta gttaaatcag
    13501 aagcataatt caatatagaa agcacaccta aatctccatg acaatatgta gggttattgc
    13561 caatgccatt acgaatagaa gaatctattg cagtcgatat ttctttttca atgtactcgt
    13621 cttcaaaacc attatctttt aaaatcaatt tacttaaaag tatacctgga gctccgtgac
    13681 accatccatt agctaactta tctttatttt ctgtggtata ccaattattg tggtcttcag
    13741 agtacaatct cctttcaaat cttaaggccc tttgaatgac ttccaataat ttttcatcat
    13801 ttgttaactt aaaatattta tataagtatg cgataaaacc agaattacca tgggaaaacc
    13861 ctgaatatgc tgctgaaaat ttccctggcc acgatatttg ctcctcaaaa ttttttgcta
    13921 cacttaatat atgttcacaa tgagtatgtg aaatctttaa aatttccttt ttgttattct
    13981 cttcagtaat atctggtatt atggaaagca taactgctaa actacctaaa gaccctccta
    14041 ttaaatcgta tactttatcg aatttaccta acttcgataa aacaccgatg ttttcaagcg
    14101 aggtcttcct taattctgaa tctccaaata aattagataa cttatttaat gtataaaaat
    14161 atcctgatat accttgaaat gcacctatta aatatgggtg atcttctttt atttcagaga
    14221 taaacttctg tattggtctc atagtttcga tagctgcttg cttaaaatcc tttctgttga
    14281 ggatttcgcc caagtaccct aaaaatagag caatccctga attaccatta tatatatcga
    14341 atcccaatac atttgcattc caaatgtctt cctcaatacc ctcaagacta ggacctatcc
    14401 acattctatc tttttgtttt ttatttatac cacatacact gttttcaact ataaattcgc
    14461 ctatctgggt tgcttcatct atccaatttt ctgacttaat tttatttaag cttgcagctt
    14521 tagagaattt tatatcagta acttctttca atcttttttc attactaatg taagacattt
    14581 caataaaatc aatctgtctt ttcaaatctt ctttcgaaag attgaaaatc ttttgcttta
    14641 ctgtttttat tggaggttct tccagaatgc tgtgaattct tttccctcta gaatctatta
    14701 aatgttcatg ttcaatagag gatctaaaaa atggaacgtc cccagttaat aaatctttat
    14761 attctgagtt caatatatct ttatactctt gtatataatc aatgccgatt ctatgtaaaa
    14821 taatcttacg tctataggta tctctcataa aatctggatg acttgagatt cttaaaagct
    14881 gagtgtataa gtaagtgggt ctgaagataa acctgctatt tgtttcttta aaagtttgag
    14941 aaattttatc ccagaattca tctttattta acatcaccca actatataaa cttgcaaaac
    15001 catctttaat ttgtcccgta taattttctg aatataagta agaccctgtt ttaatggaag
    15061 ggttgtttaa ttgaggttta atgaaagtat tttttcttaa aattttaatc gtatctgttc
    15121 ctgcattttc aattactaat gatttatgag gagagagttg ttccttatag gcagctaatc
    15181 cccctatatc tagacttatg tctttgtctc ctactctctt agaaattttt gtaggcaata
    15241 aacttattga ctgtacagag ttatcaacta attcagttgc tttaacaaca gctgactttt
    15301 tatcaatttg gtcaaccttt agtcttgcat gaaataatga ttctaagtca actaatactg
    15361 ggaaagaacc atgggctatt aaattttcat gatgaaaatc tactgcattt agaagataca
    15421 gtaaacaaag aagattacct gaacgagtat agaaatcatt tgcttcgttt ttattaaaac
    15481 aacttttata atctatgtgc tccatccaac ctgaatcatt tactgtatgt atttgaactc
    15541 ttttgaaatt taaaattccc ggtatgtttt tctcgcccaa ccaatataat acttcctgga
    15601 aaccttgttc aagcgttaaa tctctgggtt tataaattat tttcttgcca cttttaaaat
    15661 atattgttga aacagatttt cctttttgat gagtatctcc tagaccggtg gttatatttg
    15721 ttattgcacc taaatcgtta tcagagttga atttagagtt taatgaacta atttctcgtt
    15781 ttgtgttttt tattatttcc attacatatg tgaaataatc atcaatcgtt acacataata
    15841 aacttgttaa tacttcatat tctttataaa cactttttaa aaatgattca tcatttaaag
    15901 atacaactaa aaaatgattt agtctttctt ccggggtagt cccctctaaa ttcccctcta
    15961 atcttgcaat attcacttcc aaaacaagaa ccctaaaagc tttttcaaac attaaatcca
    16021 ttatatgttt aattaccttt ttcacaaatt catcctcatt atctactgca tcttcaattc
    16081 ttacttttac taagaattct tcaattttgc agttaagaaa aggagaaaaa aaatgaaaaa
    16141 atggattatg ctctaaaaat tcttcagaat ttctcactaa aaaatcactt tttttatgat
    16201 ctaagactct atcaatatct ataatacttt tattttgctc aatattagta tcgtctctaa
    16261 ttaatgattg aatcgtctta ccagatacat ttaaaaaaat cttttgcaat tcatctttat
    16321 tgttaacctc aggaaacatt ttcatccagt attggagatt atatttgtta gttttcaaag
    16381 ttaatgatcc taccttaata tattttttgc aaaataggca gttaattaca ctgcctattt
    16441 tatacttatt tcagcaagta ccttgacatt ctttagtacc tgtacaaact ttgcctttat
    16501 ttccaagaac ctcacttact aaaatgcccc ccaggctagt agttgttgta ttccaggtat
    16561 tgaaagctcc tgaaacttca tgttctttaa tttcttcaag aacatctcca catgggtcta
    16621 tcaaatttaa atcttttgtc actttcaatt ctggtgtttt taatatcttt gtcttcttca
    16681 tactatctac ctcctcattt tttactggat aaaatctcta ttaacctgtt caataataat
    16741 ctaccatatt ttcctatagt aaacaatggg ttttatgtaa tttttttatt ttatgagatt
    16801 ctcggggggt attttatact ttattttaac agggcagttt tttataatac caaaaagaag
    16861 tcctttgttt ttaggaatgt aatttttaaa atgctttagg aaagaaataa aacggttttc
    16921 acattactgc atcacaaatt ttaaaataaa aaatatcgta atcctgcctt ttgcaagtaa
    16981 aagaacaaca gttatgttac acaggaactc ttatttaaag gagagaatac tttcttttgg
    17041 agttgtcatc aaaattattt agattaataa ggaattaagt aactattatt ttgttctgag
    17101 agggcgtcaa cacaatcagc tactacctta acttttataa gtattatatg cagctaaatt
    17161 ccgggcagct gtagaccatt gttttttatc tagggcacag ctaatgacta tccgttctgt
    17221 atctgagatg gctgaattaa ggatataagt atctgtgatc acaagattgt ttacttctcg
    17281 ttttaggaat attgaaaggg tcagaccatg ctttgtcatt aactaaatac tagttatact
    17341 cacaacctta cattaattga atgttttcat taaatttgaa gaagtgtccg agttggtgag
    17401 ttttattgag cggataccat gatccaatgt atacagttgt tcaaacatgg tttatttttc
    17461 aatacttctc tcggggtcta agagagtttt ctcctgatgc agtaaccaga ttcctactag
    17521 ataccgggag ttccatatca taaaatgcaa atgttatcat ttcttgtatg ttttcttgat
    17581 tccaagcgtc tgctattcgc taaaccgaca gttactccgt aaaaagtaat aaccatcctc
    17641 ctgtaagctt taaagcttca ctgtcctttt tcaagatcgg ctagtgaaat ttttagcctc
    17701 agatattcga tccgagtaat attagtaggt ctgtactctc gaacatccat tcatcaaggg
    17761 agatatctgg ttttatgcgc taagctcgag cgtagttatc atttctttat tcaccctatt
    17821 gtcatgactt ttaaaagtgc ggcatcttat ttgaaacttt gcaagttcag tttggtctta
    17881 attatccata ttcccaacct aacattgtag gaaatgcgta aagataaact gattttgatc
    17941 attcaaacac tccaactcaa aaaaaccctg actgcttttg tcagggtaat agaaattcta
    18001 gaaattcagc tctcccacac ttaaaagggc ttggctgcag atgcagccaa gcccttttta
    18061 tgcttactta ttcaagttat agaaagagtt gataccgtgg tattgagcag tttcagccaa
    18121 ctgatcttcg atgcgaagaa gctggttgta tttcgcaaca cggtccgtac gggacggagc
    18181 acctgttttg atttgtcctg cattagttgc cacagcgata tcagcgattg tgctgtcttc
    18241 agtttcacct gaacggtgag agataacggc agtgtagccc gcgcgtttcg ccatttcgat
    18301 cgcatcgaat gtttcagtca atgtaccgat ttggtttact ttgatcagga tagagttgcc
    18361 tacgccgttt ttgatacctt cagcaagctt tttcgtgttt gtaacgaaaa ggtcgtcacc
    18421 gacaagctga acttttttgc caagacgctc tgtaagaagt ttgtggcctt cccagtcgtt
    18481 ctcgtcaagt ccgtcttcga tagagatgat tgggtattta gaaaccattt cttcgtacca
    18541 gtcaaccatt tcagcagatg ttttcacaac gccttcgcca gacagatggt atttgccgtc
    18601 ttctttgttg tagaactcag aagatgcagc atccatagca agcttcactt cttcgccagg
    18661 tttgaagccg gctttttcga ttgcttcaac gattgtttga agcgcttctt cgttagaacc
    18721 aaggttcgga gcgaatccgc cttcgtcacc tacagctgtg ttcattcctt tagcagaaag
    18781 aactgatttc aggctgtgga agatttgagc gcccatgcga agcgcttcac ggaagttagg
    18841 cgcgcctaca ggcataatca tgaattcttg aatgtctacg ttgttgtcag catgctctcc
    18901 gccgtttacg atgttcatca tcggtacagg aagcgttttt gagttgaatc ctccaaggta
    18961 ttggtaaaga ggaatctgta agaaatcagc agctgcgcgc gcacaagcca tagatacgcc
    19021 aaggattgcg ttcgcaccga gtttgccttt gttttcagtt ccgtcaagct cgattaaaag
    19081 ctgatcgatt gcgttttgtt cagttacgtc aaagccgaga agctctggag aaatgatttc
    19141 gtttacgttg ttaacagcag ttaacacgcc ttttccaagg taacggtctt tgtcgccgtc
    19201 acgaagctca accgcttcgt attcacctgt agaagctccg cttggcacta atgcgcggcc
    19261 gaaagctcct gtttctgtat atacttcaac ttcaactgtt gggttgccgc gggagtcgag
    19321 gacttcgcgt gcataaacat caacaatgta tggcatgagt ttgtctctcc ttttgattta
    19381 cgcttatttt tgaattaaag atgttcctgt catttctttc ggtttttcaa caccgagaag
    19441 gtctaataac gttggtgcga ggtcgcctag gattccgcct tcgcgcagcg tcacgccttc
    19501 tttcgtcaca atgactggga ctgggtttgt cgtatgggca gtgtgcggtt cgcctgtttc
    19561 tgtaatcaga atgtccgcat taccgtgatc agcggtaatg atggcatgtc cgcctttagc
    19621 gatgatggcg tcaaccactt cgcctaagca ttcgtccact gcttcaattg ctttaatcgt
    19681 cggttcgacc attccggagt ggccgaccat gtcagggttt gcaaagttca ggatgatcgc
    19741 gtcgtgcttg tcagccgcga tttcttttac aagagcatcc ttcacttcat acgcgctcat
    19801 ttcaggcttc aggtcatatg tcgcgacctt cggcgagtta atgaggatgc gctcttcgcc
    19861 cgggaattct tcttcgcggc cgccgctcat aaagaacgta acgtgcggat acttttcagt
    19921 ttctgcaatg cgaagctgtt ttaacccgtg ctgtgctaat acttcaccca ccgtattgtc
    19981 aaggtttacc ggtttaaaag ccacatatcc gtcaacagat tcactgaagt gagtcaggca
    20041 gacgaaatac aggtttttcg gatgattttc accgcggtcg aaatcgcgga aatctttgtt
    20101 ggtaaacgtg tttgaaatct ggatagcgcg gtccggtctg aaattataga aaatcacaga
    20161 atcgccgtca tgaattttcg caacgggttc accgttttct tttgtgatga cggacggaat
    20221 gacgaattca tcatgaatgc cgttcgcata agaatcatcg actacatcca tcgcgctgcg
    20281 gtaagacggg ccttcgccgt aagccattgc gcggtacgct ttttccacac ggtcccagcg
    20341 tttgtcgcgg tccatggagt agtagcgtcc ggaaatgctg gcgatttcgc cgacaccgat
    20401 ttcttcgatc tgctcattca gctgctgaat gtaagttttc gctgtttgcg gacctacatc
    20461 gcggccgtcg aggaaaccgt gaatatacac cttcgtcagt ccttcacttt tcgcaagctt
    20521 cagcagcgcg aataaatgat tgatatgact gtgtacgcct ccgtcagaaa gaaggccgaa
    20581 caggtgcagc gctttgtcgt tgtctttcgc gtttttgatg gcgtcaagga acgtttgatt
    20641 gcgttcgaat tcgccttcgc ggatggcaac gttcacgcgt gttaagcttt ggtacacaat
    20701 acgtcctgcg ccgatattca aatgaccgac ttcagagttc cccatctgtc cttcaggcag
    20761 tccgactgct tcgcctgatg ccgtcagcgt ctgatgaggg tattggttcc aataacggtc
    20821 gaaattcggt tttttcgctt gtgcgactgc gtttccgact gtttcattgc gtaatccgaa
    20881 cccatcaaga atgatgagtg cagctggttt tttactcata ttgaccttcc tccaataatt
    20941 gaacgaatga ctgcggttca aggcttgcgc cgccgaccaa agcaccgtca atatcggact
    21001 ctgccatata ttctttaata tttgcaggtt ttacgctgcc gccgtattga atgcggagct
    21061 tgtcagcagt ttcctggctg aagctttcag caacgacttt acggatatgc gcgcagacgt
    21121 cgttagcatc tttcgctgta gaagatttgc ctgttccgat tgcccagatt ggctcatacg
    21181 caataacgga agcggcaact tgctcttcag aaagacccgc aagacctttt ttcacttgat
    21241 cggcaacaag atcatttgtt tttccggctt cgcgctcttc aagcgtttca cctacgcaaa
    21301 tgatcggcac aatgccgtgt ttgaaagcgg catgcgcttt tttgttaact gtttcatcag
    21361 tttcagcgaa catttcacgg cgctcagagt ggccgatgac gcagtaatcc acgccaaggt
    21421 ctttcagagc gaccgggctg atttcacctg tgaacgcacc gttttcttca aaatgcatgt
    21481 tttgggcgcc gactttcagg tcagttcctt taacagcaga agtcagcttt tctaagaaaa
    21541 gagctggtgc gcaaacaacg gcttccgctt tgtctgctgc tggaatggaa gatttcactt
    21601 cttcaacgaa gctgacagct tcgccgagtg ttttgttcat tttccagtta ccggctataa
    21661 ttggttttct catctgttcc acttccttat agcagttttt atttatcgtt cagcgcagct
    21721 acacccggaa gctctttgcc ttccatgaat tcaagggatg cgccgccgcc tgttgagata
    21781 tggctcattt tgtcagcaag gccgaatttt tcaacggctg ccgcagagtc tcctccgccg
    21841 atgacagagt atgtatcgtt tgcctctgcc aatgcttcag ccactgcttt tgtgccttga
    21901 gcgaacaagt cgatttcgaa tacgcccatc ggtccgttcc atacgacaag tttgctgttt
    21961 ttgataactt cagcatacgt ttcgcgggtt ttcgttccga tgtcgatcgc ttctaaatca
    22021 cttggaatct cagagatcgg cacgatttga acgtttgcat cgttagagaa atcatcagca
    22081 acgagcacgt cttccggcat atagaatgta acgccttttt ctttcgcgcg gtccatgaat
    22141 gattttgcaa gttcgatttt atcttcttca agcaaagatt taccgacttc atagccaagc
    22201 gcttttacga atgtgtaagc aagacctccg ccgatgatca ggttgtccac tttatcaagc
    22261 agactttcga ttacgccgat tttgtctttt actttcgcgc cgccgatgat tgccgtaaac
    22321 gggcgctcag gatttgtcac ggctttgccg agaacgtcaa gctctttttc catcaagaat
    22381 cctgcaaccg ccggcagatg ctcggcaatt ccggctgtag atgcgtgagc acggtgggca
    22441 gcaccgaatg cgtcattgac atatacatcc gcaagctcag caaatgcttt agcaagctca
    22501 ggatcgtttt tctcttcacc agggtagaaa cgtacgtttt ccaatacaag aacgtctccg
    22561 tccttcatat cagaaatttg tgcttttaca gcatcgccgt aagcttcatc cgcttttttc
    22621 acttcttttc cgagcagttc gcctaagcgt gcagcgacag gagttaaacg aagctcctca
    22681 accacttcgc ctttcgggcg gcctaagtgg ctcgcaagaa ggactttcgc gccttggtct
    22741 gcaaggtgtt tgattgttgg aagcgcagct cggatacgag tatcgtctgt tacttccccg
    22801 tctttcattg gaacgttaaa gtcaacgcgg cagaatacga ctttgccttt tacgtcgatg
    22861 tcttttactg tttttttatt catgccttag gagatcctcc ttcaaaatgg tttgcatagc
    22921 acgaaaaacg tgaaacgtga aaccgcctca tgatgcttcc gccgcggggc agattgcagc
    22981 ttccgggcac ggggcagatc gtcttctgag ccagggcagg cggctaagaa aacgaaagtg
    23041 ccgcggaaac ttcaaaacgc ggacgttctg cagcaatccg gcgctttctg aaagccggtt
    23101 ctcatggaaa aagggaaagg gagtccgtcc ccttcccttg tccgctttca ttatagcgtt
    23161 tctgtccgaa agaaccaagt ccggcccttt ccgggagcta tgaattaaag accttgtttt
    23221 gcgatgtaag ctgcaaggtc aacaacgcgg ttagagtagc cgctttcgtt atcgtaccaa
    23281 gagattactt ttaccatgct gccttccata accattgtag aaagagcatc gattgtagaa
    23341 gagttagcat tgccgttgta gtctccggat actaatggct cttcgctgta gccaaggatt
    23401 cctttaagat cgccttcagc cgcttcttta agagctgcgt ttacgtcttc agccgttacg
    23461 tctttgttca gttcagcaac taggtcaaca agagaaacgt ttggagtcgg cacacgcata
    23521 gctccgccgt tcagtttgcc tttcagttca ggaagaacga gggaaactgc tttagcagcg
    23581 ccagttgatg taggaatgat gttttcagct gctgcacgcg cacgacggta gtctttgtgc
    23641 ggaagatcaa gaatttgctg atcgtttgtg taagagtgaa cagttgtcat cataccgcgt
    23701 ttgatgccga atttgtcgtt aagtactttt gcaaacggcg caaggcagtt tgttgtgcaa
    23761 gatgcgttag agataacatg gtggttagcc gcatcgtatt tgtcttcgtt aacacccata
    23821 acgattgtga tatcttcttc gttagcaggt gcagagatga taactttttt cgcgcctgct
    23881 tctaagtgtt tcgcagcgtc tgcgcgtttt gtgaagaaac cagtagattc aactacgatt
    23941 tcaacgcctt gtttgcccca gctgagtttc gcaggatcgc gctcagcaga aacttcgatt
    24001 gttttgccgt taacaacaag gttgctgccg tcaactttaa cttctgcatc taattttccg
    24061 tgtacggaat catattgtaa aagatgagca agcatgttag cgtctgttaa atcgttaacc
    24121 gctactacct caacttcagg attgtttaat gctgcgcgga atacgttacg tccaatacga
    24181 ccaaaaccgt taataccgac ttttactgcc atgattattt cctcctttaa ataagtgaga
    24241 gatatttata ttgagggact gttatccctt aataacttct ttgcggctcc ttcgtccgtg
    24301 acgagaaccg tgtttcgctg ctttttaaaa taagcttcga ttgcttctgc ttttgatgat
    24361 ccgcccgcta ccgcgataat gtcgggaatg gcatcgaggt catcaagctg cattccgact
    24421 gaatgcacct tgtgaacgac ttctccgtcc gcattaaagt agtagccgaa tgcctctgtc
    24481 accgcatgat tgtcatctat tttcttcaaa tcttccaaag gcgtgtttct tcgctccgcc
    24541 attgttctag cttcgccgat tccgtgaacg agcatactcg ctgatttaat cgtgtgaagc
    24601 acctctttta cggaaggctc ttcaataata gatgagtagg cgccttgtga cagctgcccg
    24661 ggaacgaaca aaagccggta agtgcctgaa gccttttccg ccatatgcgc gcatatggtg
    24721 ttcgcctggt ttttcacatc ttcgcctaaa ccgcctcttg cgggcacaaa caggagctcg
    24781 cggttttttg aatccggcgt catcatatcg gcgacggctt caattgtcgt accgccggtt
    24841 acagcgacga tatttttgcc tgaaaatctc tttttcatac atgcaacggc cgctctccct
    24901 aattcttttt tgacccaagg agattggtcg ctgtctccgg aaacgataat ggcgtctttc
    24961 agattaagcc gctcttttaa tgtcttttcc aaaagcgtca atcctaaaac atccttcatc
    25021 gtatcttcca gaatcgaaag cagtgagtag ccctcttccg tcattgtcat gccgtttgtt
    25081 ttaatatcga tgagattctg ttctttcaaa aactgaacct cgcttctgag aacgcgctcg
    25141 gtcaatccga gactggctgc aagacttctg cggccgatcg gttcggtaag cctgatatac
    25201 tgcaagattt caaatctttt ctgcatcaca agcaaaagat caggcaataa ttttttttga
    25261 gcttgtatta actggttcat gactcaaacg ttccttccta ttcatactgg acagaaaatg
    25321 tcccgctatg acaaaaaacg tcccatcata gccaaaaaaa attatgtctg ctttctttaa
    25381 ttattttaac aggatgacat tgttaattca actgttaaag gtcaattcgt cgacattctt
    25441 cgcaggattt cccagtatct ccttgataca gtcattatat acagaaacgg aatgaaggtg
    25501 acagacaaaa gcccgccgga gcggactttt gtcgtaaaac gctttcattt tatccagagt
    25561 ttttctattt cttctaatga tttatttttc gtctcagggc agatcgtcac gacaaacaag
    25621 aaacagagaa tattaatgac ggcgaatatc cagaaggtgt acgcgagccc taacccgctg
    25681 atcatcatcg gcacgaactg gccgatcgcc cagttggccc cccataagaa tatcgtcgcg
    25741 ataccggcgg cgcgtgcgcg gaggtggttc ggaaagattt ccgaaatcat gatccacgta
    25801 atcggcccga ctgatacgca gaaagcggcg acgaatccca atatgatgac gactaaagcc
    25861 ggaccgctcg ccagcttaaa ataaaaggat gccccgatta agatcatgaa cagcgccata
    25921 aaggctgatc cgacccccat cagctttttc cggcccacct tatcgactaa aagaaccgcg
    25981 ataatggtga aaatcacttc aacgacaccg acgatgcatg tcgtgataaa ccccgcattc
    26041 tgtccgaagc ccatcatttt gaaaatttcc ggcccgtaat acgtaattgc gttcatgccg
    26101 atgacctgat tgaataaagc cagcagaatc ccgatcacaa gcgcttttct cagccccggt
    26161 ttaaacagct gagacaatga ccccattttt tctaattgta aagacgtttc gatttgtttg
    26221 atttcttctt tcgcggtctg ctcgccgtta atgcgcgtca gcacggcgag ggcttcattc
    26281 cggcgccccg ctttcgcaag ccagcgcggg ctttcaggca cgataagcag cacgataaaa
    26341 aagatgacgg acggaatcat gccgtaagcg agcatcca
//
