LOCUS       NZ_CP032855            23189 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis subsp. subtilis strain PJ-7 chromosome, complete
            genome.
ACCESSION   NZ_CP032855
VERSION     NZ_CP032855.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis subsp. subtilis
  ORGANISM  Bacillus subtilis subsp. subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4293706)
  AUTHORS   Kim,S.-J., Heo,J. and Kwon,S.-W.
  TITLE     Genome sequencing of strain PJ-7
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4293706)
  AUTHORS   Kim,S.-J., Heo,J. and Kwon,S.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2018) Agricultural Microbiology Division, National
            Institute of Agricultural Sciences, 166, Nonsaengmyeong-ro,
            Iseo-myeon, Wanju-gun, Jeollabuk-do 565-851, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2018
            Assembly Method                   :: RS HGAP Assembly v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 222.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003665215.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:29:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,711
            CDSs (total)                      :: 4,590
            Genes (coding)                    :: 4,234
            CDSs (with protein)               :: 4,234
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 356
            CDSs (without protein)            :: 356
            Pseudo Genes (ambiguous residues) :: 0 of 356
            Pseudo Genes (frameshifted)       :: 219 of 356
            Pseudo Genes (incomplete)         :: 131 of 356
            Pseudo Genes (internal stop)      :: 56 of 356
            Pseudo Genes (multiple problems)  :: 44 of 356
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:07:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1917672
            Orig. end                         :: 1940861
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032855.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23189
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="6"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23189
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23189
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13189](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13189
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    322..336
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 21.98"
                     /tool="antismash"
     gene            complement(546..1319)
                     /gene="yxdL"
                     /gene_synonym="tpeL"
                     /locus_tag="D9C11_RS10400"
                     /old_locus_tag="D9C11_10400"
     CDS             complement(546..1319)
                     /codon_start=1
                     /gene="yxdL"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /gene_synonym="tpeL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391843.2"
                     /locus_tag="D9C11_RS10400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10400"
                     /product="ABC transporter ATP-binding protein YxdL"
                     /protein_id="WP_121591318.1"
                     /transl_table=11
                     /translation="MANMLEVKHINKTYKGQVSYQALKQISFSIEEGEFTAAMGPSGSG
                     KTTLLNIISTIDRPDSGDILIHGENPHRLKRTKLAHFRRKQLGFVFQDFNLLDTLTIGE
                     NIMLPLALEKEAPSVMEEKLHGIAKKLGIEDLLNKRTFEVSGGQRQRAAIARAVIHKPS
                     LILADEPTGNLDSKASKDVMETMQSLNQDDHVTALMVTHDPVAASYCRRVIFIKDGELF
                     NEIYRGENRQVFYEQILDVLSMLGGNANDLSSVRL"
     gene            complement(1464..2276)
                     /locus_tag="D9C11_RS10405"
                     /old_locus_tag="D9C11_10405"
     CDS             complement(1464..2276)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391844.1"
                     /locus_tag="D9C11_RS10405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10405"
                     /product="sensor histidine kinase"
                     /protein_id="WP_121591319.1"
                     /transl_table=11
                     /translation="MKLFLRSHAVLILLFLLQGLFVFFYYWFAGLHSFSHLFYILGVQL
                     LILAGYLAYRWYKDRGVYHWLSSEQEGTDIPYLGSSVFCSELYEKQMELTRLQHQKLYE
                     TEAKLDARVTYMNQWVHQVKTPLSVINLIIQEEDEPVFEQIKKEVRQIEFGLETLLYSS
                     RLDLFERDFKVEAVSLSELLQSVIQSYKRFFIQYRVYPKMDIRDDHQIYTDAKWLKFAI
                     ENGRRFQESTGIGLHLVKEITGKLNHTVDISSSPGEGTSVRFSFLTKM"
     gene            complement(2273..2961)
                     /gene="yxdJ"
                     /gene_synonym="tpeJ"
                     /locus_tag="D9C11_RS10410"
                     /old_locus_tag="D9C11_10410"
                     /pseudo=""
     CDS             complement(2273..2961)
                     /codon_start=1
                     /gene="yxdJ"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /gene_synonym="tpeJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391845.1"
                     /locus_tag="D9C11_RS10410"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10410"
                     /product="two-component system response regulator YxdJ"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNKIMIVEDSEDIRGLLQNYLEKYGYQTVVAADFTAVLDVFLREK
                     PDVVLLDINLPAYDGYYWCRQIRQHSTSPIIFISARSGEMDQVMAIENGGTIISKNRFL
                     MILCWRKSKARSGGRTGSTPQSRERKWLNMPASSSLWNGLNCVFRMKKASFLKKKASFW
                     KCCWSGEKR"
     gene            complement(3111..4550)
                     /locus_tag="D9C11_RS10415"
                     /old_locus_tag="D9C11_10415"
     CDS             complement(3111..4550)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118835.1"
                     /locus_tag="D9C11_RS10415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10415"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_121591320.1"
                     /transl_table=11
                     /translation="MKLRNRIAFYFVSRLFLLMFIWGLLMVGSIIFFSLVLGQNKMETP
                     QLSLKKIVAQTVVADKQFSINTKAKEDLLENRMWIQILDEQGDEVFSFNKPKNIPKHYI
                     LGELISDYMYPAKKGYQLSTWYETKNNQDLTWVLGKPMEKNNPFFYWVNNLWIVSIIMA
                     GIVIAIFYGKKLGAPLLFIVSWIENLSKEKYEEPYDRKFHSSKYRHNKSGYKTYQELMQ
                     ALSELTSTLQRNKAERELLEKTREEWMAGVSHDLKTPLSVIKGYTVLLSSNEYEWENQQ
                     VRDFSLIMEERVEYMEKLIEDFNLTFQLKNESLPIHLEEKNVVKVIHDTLEKMKLLPES
                     ENKRFALESSHNKILFNMDERYLKRAVENLIANCIKHNPPGTKIKVILYQDVLHDNEIQ
                     ITIEDDGIGMDEETVECLFDRYFRGISASSNNSGTGLGMAIAQQIIKAHGGNIDIYSQP
                     GVGTRFKITFPKPPSKYNNVN"
     gene            complement(4547..5269)
                     /locus_tag="D9C11_RS10420"
                     /old_locus_tag="D9C11_10420"
     CDS             complement(4547..5269)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015418566.1"
                     /locus_tag="D9C11_RS10420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10420"
                     /product="response regulator transcription factor"
                     /protein_id="WP_077723063.1"
                     /transl_table=11
                     /translation="MTLEENKILMVDDDEHILNLLITCFEKEGFSNISTAMTGSETLLK
                     IDQELPNIILLDVMLPDTDGFTLCSKIRSHTNVPILFLTAKTTDLDKLQGFSFGGDDYI
                     TKPFNPLEIVARVKAQLKRTTQLSSSYPLKQVYDYEYFKIDPNTGRLVVNGTRIDCPAQ
                     EMKLLIYFCEHPNQILSKHQIYKDVWGEFYGGDSTVMVHVRRLREKLEEDPSRPRWIKT
                     VRGQGYIFEAEPIDEELL"
     gene            5512..6423
                     /locus_tag="D9C11_RS10425"
                     /old_locus_tag="D9C11_10425"
     CDS             5512..6423
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118837.1"
                     /locus_tag="D9C11_RS10425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10425"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_058906455.1"
                     /transl_table=11
                     /translation="MNDQIVVTHDLTKKYKKHTSVDGLNLRIRRGEIYGFLGPNGAGKT
                     TTIRMLLGLIKPTKGNIEIFGQNLNKNRLQILQRIGSLVESPTYYGNLTGYENLEAVRR
                     LRGLPEQRVNEVLETVRLSKVANRLTKEYSLGMKQRLGIAVALLSSPDLLILDEPTNGL
                     DPSGIQEIRELIKELPKSGMSVVVSSHLLSEIDQMATQVGIINNGRMIFQDSIASLHQK
                     RKPLLKVGVSDVIEAKTILNRKGLKVDLQKNYLWLSQTEPEFVSEINSILLHSGLSVFR
                     LEEKTRSLEDIFLELTGTEGSL"
     gene            6420..7178
                     /locus_tag="D9C11_RS10430"
                     /old_locus_tag="D9C11_10430"
     CDS             6420..7178
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007614844.1"
                     /locus_tag="D9C11_RS10430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10430"
                     /product="ABC transporter permease"
                     /protein_id="WP_007614844.1"
                     /transl_table=11
                     /translation="MKKLLWADQLKLKRSSLLIVVLLVPLLIIAYELVNLTYRSEYVEK
                     QAEMFHAGSMWMYLLYDNSLLFGLGFPLAATLSASIIANIEHQANGWKQTLSFPVSRMR
                     IYVSKFICLVVSLFISSTIFLLGMVLLGKLVGFEGSVPWGLLFGDSYSMLVTVLPIMAF
                     QIWLSMVFSNQAFSILVGSVSSIMGLFLAAAQSTRWFPLAYPSQSSTVILQYEGIGYNP
                     DLSSYLCISLFLGIIILFLGSIHFAKRDAL"
     gene            7195..7929
                     /locus_tag="D9C11_RS10435"
                     /old_locus_tag="D9C11_10435"
     CDS             7195..7929
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012118839.1"
                     /locus_tag="D9C11_RS10435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10435"
                     /product="ABC transporter permease"
                     /protein_id="WP_229154627.1"
                     /transl_table=11
                     /translation="MKNILFVERLKLRRSKLWIIYLLGPLLGVSLAYTNFIKNYNLFMN
                     PGDNPWVEAWTQVALFMGPFVLPIVVGIFAALVCRGEHVGGGWKQLLALPVKHSDIFLG
                     KFLTVVRMIFISMFILILLFIGFGYMLGISGSLPLLTILGYGIRGILACLPLILLQLIV
                     SIRSKTFGIPLAVSIVFTLPAIIIASTPLGQVYPWTQPMLAMSPADESPIQSNFLFYSI
                     MVITCLVLLVYGIRSFTKRDLT"
     gene            8214..8420
                     /locus_tag="D9C11_RS10440"
                     /old_locus_tag="D9C11_10440"
     CDS             8214..8420
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF000539.0"
                     /locus_tag="D9C11_RS10440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10440"
                     /product="plantaricin C family lantibiotic"
                     /protein_id="WP_029325769.1"
                     /transl_table=11
                     /translation="MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGAGDM
                     EAACTFTLPGGGGVCTLTSECIC"
     CDS_motif       8214..8339
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVGA"
                     /locus_tag="D9C11_RS10440_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       8340..8420
                     /prepeptide="core"
                     /locus_tag="D9C11_RS10440_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.00"
                     /molecular_weight="2400.8"
                     /monoisotopic_mass="2399.0"
                     /core_sequence="GDMEAACTFTLPGGGGVCTLTSECIC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSQEAIIRSWKDPFSRENSTQNPAGNPFSELKEAQMDKLVG
                     A"
                     /leader_location="[8213:8339](+)"
                     /alternative_weights="2418.8"
     gene            8516..8968
                     /locus_tag="D9C11_RS10445"
                     /old_locus_tag="D9C11_10445"
     CDS             8516..8968
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D9C11_RS10445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D9C11_10445"
                     /product="winged helix family transcriptional regulator"
                     /protein_id="WP_250621989.1"
                     /transl_table=11
                     /translation="MGKTLVCSENSYFQAYMNHLLTPDSNEIINVNTLDELKQIISKEI
                     FSSVIIDTCHPNDLVLQLIKSISCPVIILNSLETNVSDYNPGPILNQINNVSTLKHNVF
                     QLSFTTFFDVGKHCIWKKNEYIPLAIQEFKILYLLYLNSNKIVCSE"
     misc_feature    8532..8546
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.88"
                     /tool="antismash"
     gene            9017..9157
                     /locus_tag="D9C11_RS24030"
     CDS             9017..9157
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012698.4"
                     /locus_tag="D9C11_RS24030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_250621997.1"
                     /transl_table=11
                     /translation="MSSLREKVEDNPGDPKILQTKFGKGYLLSDSTYICLEKKADSKNV
                     V"
     gene            complement(9206..9790)
                     /locus_tag="D9C11_RS10450"
                     /old_locus_tag="D9C11_10450"
     CDS             complement(9206..9790)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007614850.1"
                     /locus_tag="D9C11_RS10450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10450"
                     /product="flavoprotein"
                     /protein_id="WP_121591321.1"
                     /sec_met_domain="Flavoprotein (E-value: 8.4e-27, bitscore:
                     91.7, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSISILKDKKLLIGICGSISSVGISSYLLYFKSFFKETRVVMTKT
                     AEDLIPAPTVSYFCDHVYSEHGENGKRHSHVEIGRWADIYCIIPATANILGQTANGIAM
                     NLVATTVLAHPHNTIFFPNMNDLMWNKTVVSRNIEQLRKDGHIVIDPVEIMAFEIATGT
                     RKPNRGLITPDKALLAIEKGFRERTKHPSLT"
     gene            10001..13189
                     /locus_tag="D9C11_RS10455"
                     /old_locus_tag="D9C11_10455"
     CDS             10001..13189
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014419285.1"
                     /locus_tag="D9C11_RS10455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10455"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_121591322.1"
                     /sec_met_domain="DUF4135 (E-value: 5.4e-113, bitscore:
                     376.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.8e-87, bitscore:
                     290.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHTKLKWNSVWNRSSSISERKVRRPLNTNWDELTNRRFERWKSLV
                     ESDEGIRIENVLATQNIDEETLKHTINAKEVEFINESDHLGWLEIIQLVDEQSYKDVNI
                     EVRKDILFFSFIKPFLKIARGKLEEVLYSHSNKSLIKEELSPSVIDDSLNILGETLSAI
                     SSRILILELNVARVAGKLRGETSEERASYFNKVLLNDPAYVRSIREEYIVLTRLLATKT
                     MYWIQNTSELLIRFHQDKGLLESEFTNGQKLGKVISIDTGSSVSDTHNKGKTVAILNFE
                     TGIKIVYKPRSLEIDVKFNKFVNYLNGKNLSFDLKTVHTLNKKSYGWTQFISYKECQEE
                     LQIGKFYWRIGSYLAILYAMNAVDFHMQNLIAEGEYPILVDLESLFHNNSTYTDTSAFS
                     LAQEHIERSVLRIGLLPRKINSKAGFEGIDLSALGAQEGQVSPHKTSTIVDRDKDTVRI
                     EEKNFPIPVSQHRPMLHGQIINSVAYEGDIIKGFEETYFLFMKYKQDMLEQIDSFKGVT
                     VRQILRGTSRYANLLKISLHPDFMRDGLDREMILDKLWLDTKLNPRLNQVVNSEKDDLF
                     LGDIPYFTSKPESTNMWDSNGRKINNFFKTSALNETKEKINEMNESDCHEQVSFIKTAI
                     LVIKDSYRKHKVFDINPRLHVFNPKDFFQEAIKIGDFLASRAIEGEQLDGQEDVSWIGS
                     FVDNQREDQFKISAANSSLYEGVGGISLFLAYLGRLSNDEKYTKLSKKALVAVHKNMSA
                     SSDLGAFGGIASYLYLLDHLSKLWNDEQLLKNELHSALNKLDSLIERDENNDILTGVAG
                     TAVILINLFKRYKEEQILNLITKCGNRLIQNINVMEKGVGWKVPANPTPASGFAHGASG
                     IIWALYEIYAITEQTVFKEVAEKALEFERTLFIPEKNNWADIKLENGQFRNDNFVAWCN
                     GAAGIGLGRILILPHNQNELIKDEAHVAINTTLKYGFEHDHSLCHGDLGNLDILMYAAE
                     NFNKKLSVNVTELSHKILNDIKLRGWLTGFEKNNESPSLMMGYAGIGLGLLKIFAPTEV
                     PSVLRLQSPLELKL"
     gene            13241..15442
                     /locus_tag="D9C11_RS10460"
                     /old_locus_tag="D9C11_10460"
     CDS             13241..15442
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014419286.1"
                     /locus_tag="D9C11_RS10460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10460"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_121591323.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.2e-41, bitscore:
                     138.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRRVPLVRQMGQYECGPACLTMILSYYGSTISLNKISEQCDAQR
                     NGVSVSILKSVSEYYGLNCKVYQVSFKDLKKYIHSYLPCIIFWDERHFVVLEQIKKGLF
                     HIIDPNRGKLRLSEEEFKRHYSKVILTFTKSDRFKEMMPSPAAKYYLRYIVKSRSIVSL
                     IILFSLITQVVFLAVPFLIKYLVDHSLISKSTNSFLFLGIVVIIAVFILGLVMFLRNYF
                     TIKLQAIISKSISNDFVEHLLKLPLNFYENRTTGDIAMRVSNISIIREIMAKNGVTVVL
                     DIITLISFFIAMLTQSFKLAFFAIGLAIIQFLLMMILIPRIKNLIHNDLSIQTTTQSFL
                     VEALRAITFIKSNGLDHSILTKWSNYYDKQIEAFSQRYHLDAIMDSISISIRYCAPLLL
                     LWFGSKEVITENLTLGGLLGFSSLGTSLLLPIASLITSMQQFQLVGDTFERMQDVMETE
                     PEQLNQTSIIETELSKQDIKLENVTFTHQSLHILKEVSLNIKSGTKLALVGRTGSGKTT
                     LSRIILGLYKPTKGKVLYGEEDLKNLNLYELRKQMGVVLQESFLFNDTIANNIAGFKSL
                     SQDKIEQAAKRVQLHEDIIRMPMGYNTIIGENGSMLSGGQRQRIAIARAIVDNPSVVIL
                     DEITSNLDTLTEHKIDEYFAKSNITRIVITHRLLSSQDSDLIVVLDQGKIVEKGKHQEL
                     LEKRGYYYDLWIKQVGDRQKATLEKPLFLNEPTGKTLGR"
     gene            <15548..15646
                     /locus_tag="D9C11_RS24395"
                     /pseudo=""
     CDS             <15548..15646
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014666009.1"
                     /locus_tag="D9C11_RS24395"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="KNLAAVEHNHVFINDFDTIYLYQSLSVSNRLI"
     gene            complement(15725..16597)
                     /gene="iolJ"
                     /locus_tag="D9C11_RS10465"
                     /old_locus_tag="D9C11_10465"
     CDS             complement(15725..16597)
                     /EC_number="4.1.2.29"
                     /codon_start=1
                     /gene="iolJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391846.1"
                     /locus_tag="D9C11_RS10465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10465"
                     /product="6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase"
                     /protein_id="WP_121591324.1"
                     /transl_table=11
                     /translation="MAFVSMKELLEDAKREQYAIGQFNINGLQWTKAILQAAQKEQSPV
                     IAAASDRLVDYLGGFKTIAAMVGALMEDMAITVPVVLHLDHGSSAERCRQAVDAGFSSV
                     MIDGSHQPIEENIAMTKEVTDYAAKHGVSVEAEVGTVGGMEDGLVGGVCYADITECERI
                     VKETNIDALAAALGSVHGKYQGEPNLGFKEMEAISRMTDIPLVLHGASGIPQDQIKKAI
                     TLGHAKININTECMVAWTDETRRMFQENSDLYEPRGYLTPGIEAVEETVRSKMREFGSA
                     GKAVKQQVG"
     gene            complement(16618..17454)
                     /gene="iolI"
                     /locus_tag="D9C11_RS10470"
                     /old_locus_tag="D9C11_10470"
     CDS             complement(16618..17454)
                     /EC_number="5.3.99.11"
                     /codon_start=1
                     /gene="iolI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391847.1"
                     /locus_tag="D9C11_RS10470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10470"
                     /product="2-keto-myo-inositol isomerase"
                     /protein_id="WP_014481412.1"
                     /transl_table=11
                     /translation="MKLCFNEATTLENSNLKQDLELCEKHGYDYIEIRTMDKLPEYLKD
                     HSLADLAEYFQTHHIKPLALNALVFFNNRDEKGHNEIITEFKGMMETCKTLGVKYVVAV
                     PLVTEQKIIKEEIKKSSVDVLTELSDIAEPYGVKIALEFVGHPQCTVNTFEQAYEIVNT
                     VNRDNVGLVLDSFHFHAMGSNIESLKQADGKKIFIYHIDDTEDFPIGFLTDEDRVWPGQ
                     GAIDLDAHLSALKEIGFSDVVSVELFRPEYYKLTAEEAIQTAKKTTVDVVSKYFSM"
     gene            complement(17540..18409)
                     /gene="iolH"
                     /locus_tag="D9C11_RS10475"
                     /old_locus_tag="D9C11_10475"
     CDS             complement(17540..18409)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="iolH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391848.1"
                     /locus_tag="D9C11_RS10475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10475"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_088272585.1"
                     /transl_table=11
                     /translation="MKLALDPSMYRDDLTLEETVYKTAELGYEHIELSPREDFCPFYKY
                     PKVDSAKIKQLKRLLRDTGVKLSSLLPLYHWAGPDEDRRQAAVRNWKRAIEIAVELEVD
                     LMNSEFSGSKYDPLTSEEKFIKSMDELLPVFEKEGIKLNLQAHPYDFIETHKGAMDMIR
                     ALDKDWINLVYSTAHTFFYDDGKGDIETMFDEAGDRLTHVLFADTYNHKAAHGLRYIVN
                     PPDAKVTVHQHLDIGQGEVDFDTIFRKLREMKFDGIATNAVFAWVDERADESSRFMLKK
                     MKEELGLA"
     gene            complement(18429..19463)
                     /gene="iolG"
                     /locus_tag="D9C11_RS10480"
                     /old_locus_tag="D9C11_10480"
     CDS             complement(18429..19463)
                     /EC_number="1.1.1.18"
                     /EC_number="1.1.1.369"
                     /codon_start=1
                     /gene="iolG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391849.2"
                     /locus_tag="D9C11_RS10480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10480"
                     /product="bifunctional inositol
                     2-dehydrogenase/D-chiro-inositol 1-dehydrogenase"
                     /protein_id="WP_014481414.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3.1e-31, bitscore:
                     106.6, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 4.2e-18,
                     bitscore: 63.6, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLRIGVIGTGAIGKEHINRITNKLSGAEIVAVTDVNQEAAQKVV
                     EQYQLNATVYPNDDSLLADENVDAVLVTSWGPAHESSVLKAIKAQKYVFCEKPLATTAE
                     GCMRIVEEEIKVGKRLVQVGFMRRYDSGYVQLKEALDNHVIGEPLMIHCAHRNPTVGDN
                     YTTDMAVVDTLVHEIDVLHWLVNDDYESVQVIYPKKSKNALPHLKDPQIVVIETKGGIV
                     INAEIYVNCKYGYDIQCEIVGEDGIIKLPEPSSISLRKEGKFSTDILMDWQRRFVAAYD
                     VEIQDFIDSIQKKGEVSGPTAWDGYIAAVTTDACVKAQESGQKEKVELKEKPEFYQSFT
                     TVQN"
     gene            complement(19486..20801)
                     /gene="iolF"
                     /locus_tag="D9C11_RS10485"
                     /old_locus_tag="D9C11_10485"
                     /pseudo=""
     CDS             complement(19486..20801)
                     /codon_start=1
                     /gene="iolF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391850.2"
                     /locus_tag="D9C11_RS10485"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10485"
                     /product="myo-inositol transporter IolF"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGNTNGDSAFNKRTIAAALANYIDAGSIVAGSAGLSLWVSYLKLS
                     DTQIGCSAR"
     CDS_motif       complement(20748..20801)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MGNTNGDSAFNKRTIAAA"
                     /locus_tag="D9C11_RS10485_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(19488..20747)
                     /prepeptide="core"
                     /locus_tag="D9C11_RS10485_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-2.20"
                     /molecular_weight="3529.0"
                     /monoisotopic_mass="3526.9"
                     /core_sequence="LANYIDAGSIVAGSAGLSLWVSYLKLSDTQIGCSAR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MGNTNGDSAFNKRTIAAA"
                     /leader_location="[20747:20801](-)"
                     /alternative_weights="3547.0"
                     /alternative_weights="3565.1"
                     /alternative_weights="3583.1"
                     /alternative_weights="3601.1"
                     /alternative_weights="3619.1"
                     /alternative_weights="3637.1"
     gene            complement(20816..21709)
                     /gene="iolE"
                     /locus_tag="D9C11_RS10490"
                     /old_locus_tag="D9C11_10490"
     CDS             complement(20816..21709)
                     /EC_number="4.2.1.44"
                     /GO_function="GO:0050114 - myo-inosose-2 dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="iolE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391851.1"
                     /locus_tag="D9C11_RS10490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_10490"
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="WP_069703573.1"
                     /transl_table=11
                     /translation="MGKNEILWGIAPIGWRNDDMPEIGAGNTLQHLLSDIVVARFQGTE
                     VGGFFPEPAILNKELKLRNLRIAGKWFSSFILRDGLGEAAKTFTLHCEYLQQVNADVAV
                     VSEQTYSVQSLEKNVFTEKPHFTDDEWERLCEGLNHLGEIAAQHGLKLVYHHHLGTGVQ
                     TAEEVDRLMAGTDPSHVHLLYDTGHAYISDGDYMGMLEKHIGRIKHVHFKDARLNVMEQ
                     CRLEGQSFRQSFLKGMFTVPGDGCIDFREVYQLLLKHSYSGWIVIEAEQDPDVANPLEY
                     ALIARNYIDQQLLDLA"
     misc_feature    complement(21672..21686)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    21673..21687
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 20.43"
                     /tool="antismash"
     misc_feature    complement(21981..21995)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    complement(22238..22251)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.36"
                     /tool="antismash"
ORIGIN
        1 gcttaacctt gccagtgccc tttattaatt tgataaccgt atttgatctg acaaaaagga
       61 tcgtaaactg cgataaaaag aaaaataaga gcagaaatcc gcaggccgta ataccgagcg
      121 ctttccaagg catgtacaga ggcagcgcgt ccatttctaa aatataagcg ccgaccgtaa
      181 agaacgtttt cgaaaaaatg aagcctccga taatccccgc tgcgatcgac atgacgccga
      241 tgatcatgtt ttccgccgta atgagctttc tcagctgcac cggcgtaata ccctgcatca
      301 gcagaatacc gaattcttta tttctcgatt tcaaaaatgc gttaaccgaa tacagaacaa
      361 ataagaaaga aaaaacaaag atcatccatt ccgcggcggt taagcctttt ttggcgatat
      421 tattcaggta gccctccttt aatgccggat gaaacaggaa catcgcaaag gtaaagaaaa
      481 tcaaaacgga aaaggcgctg ctcaagaaga atgcaagata ggcccttttg tttctcgtga
      541 cgtttttata agcgaactga agaaaggtca tttgcgtttc cccccagcat agacagcaca
      601 tcaagaatct gctcataaaa gacttggcgg ttttccccgc ggtaaatctc attaaacagt
      661 tcgccgtctt ttataaagat gacgcggcgg cagtagcttg ccgcaaccgg atcgtgggtc
      721 accatcaaag ccgtgacatg atcatcctga ttcaggctct gcatcgtttc catgacatct
      781 tttgacgctt tggaatcaag gtttcccgtc ggttcatcag ccagaataag tgacggctta
      841 tgaatgaccg ctcttgcgat ggcggcccgc tggcgctgtc cgccggatac ttcaaacgtc
      901 cgtttattga gcaggtcttc gattccgagc tttttcgcga tgccgtgcag tttttcttcc
      961 atgacagacg gcgcttcttt ttcaagcgct aacggcagca tgatattttc accgattgtc
     1021 agcgtgtcca gaaggttgaa atcctgaaac acaaatccga gctgcttgcg gcggaaatga
     1081 gcgagctttg tccgcttcag gcgatgcggg ttttctccgt gaatcaggat atcgcctgaa
     1141 tccggacggt cgatcgttga aatgatattc aaaagcgttg tttttccgga cccggacggc
     1201 cccatcgccg ccgtgaactc gccttcttct attgaaaatg aaatttgctt taaggcttga
     1261 taagacactt gtcctttata ggttttattt atatgtttga cttcaagcat attcgccatg
     1321 aaaatcctcc ttatggtttt attcttgttg atctgggctg ctttcatgta gtgccggggc
     1381 attcagcata aaaaatcccc ttgacgtaaa tccatgttat caaggggaaa cagaatgagc
     1441 tatgttgttt tcttaacgca gtcttacatt tttgtaagaa atgaaaatcg gaccgatgtc
     1501 ccttcaccgg gggacgagct gatgtccacc gtatgattga gcttgcccgt aatttctttg
     1561 acgagatgga ggccgattcc cgtagattct tggaaacgcc gcccgttttc gatcgcaaat
     1621 ttgagccatt tggcatcggt gtaaatctga tgatcatcgc gaatgtccat tttcggataa
     1681 acgcggtatt gaataaaaaa tcgtttatag ctttgaatga ccgattggag aagctctgat
     1741 aaggaaaccg cttcgacttt aaaatcccgc tcaaacaggt caagccttga tgaataaagg
     1801 agcgtctcca gcccgaattc aatctgccgg acctcttttt tgatttgttc aaagacgggc
     1861 tcatcctctt cctgaatgat taaattaatg accgacagcg gcgtttttac ttggtgcacc
     1921 cattgattca tatacgtcac ccgcgcgtcg agcttggctt cggtctcgta gagcttctgg
     1981 tgctgcagcc gggtcagctc catctgcttt tcatacagct ctgaacagaa cactgaagaa
     2041 ccgagatacg ggatgtccgt cccttcctgc tccgagctga gccaatgata cacaccgcgg
     2101 tctttgtacc agcgataggc aagatacccc gccaaaataa gaagctgcac gcccaatatg
     2161 taaaacaggt gggaaaaaga atggagaccc gcaaaccagt aataaaagaa gacaaacagc
     2221 ccttgaagga gaaaaagcag aatcagcacg gcatgagacc ggagaaacag cttcatgaca
     2281 gcgccctcag ctggtagcct tcgccccgca ccgattcaat ggaaacaggc gcgttcagct
     2341 cccgcagttt ttttctgagc cgcgtgatat acacgttaag cgtattatca tcgacgaaaa
     2401 tgtcggtgtc ccacgttttt tccatgagcc ggtctcttcc cgtcaccttt tctccccgct
     2461 ccagcagcac ttccaaaagc ttgctttctt ttttagaaag ctcgcttttt tcatcctgaa
     2521 aacgcagttc aaaccgttcc ataaagagct ggacgccggc atattcaacc actttctctc
     2581 cctgctttgc ggcgtactcc ccgtacgccc tccggatctg gcttttgatt ttcgccagca
     2641 caatatcata agaaaacggt ttttcgatat aatcgtcccc ccgttttcaa tcgccatcac
     2701 ctgatccatt tccccgcttc tggcagaaat aaagatgatc gggcttgtgg agtgctggcg
     2761 gatctgccgg caccaataat atccgtcata tgccggtaaa ttgatatcaa gcagcaccac
     2821 atcgggcttt tcccgcaaaa agacatcaag aacagctgta aaatccgcgg cgaccactgt
     2881 ttgatatccg tatttttcaa ggtaattctg caatagtccg cgaatgtctt cactgtcttc
     2941 cacaatcatg attttattca tgcaaccatc ctccaaaagg atacggcttt tcggagccat
     3001 cattatttga tgcccccatc ataatgcttt catcgcttct ctgcaacatg agaaagcggg
     3061 cctttataaa agacccgctt caccctttct caacgtaaga tagattattt ctaattgaca
     3121 ttgttatact tagatggcgg cttcggaaag gtaattttaa atcttgtgcc aactcccggc
     3181 tgactgtata tatcaatatt tccaccatgc gccttgataa tttgctgagc aatagccatt
     3241 cctaatccag tcccggagtt atttgacgaa gcgcttatcc ctctgaaata ccgatcaaat
     3301 aaacattcaa ccgtctcttc gtccattcct atcccatcgt cttctattgt aatttgtatt
     3361 tcgttgtcat gtaacacgtc ctgatataat atgaccttta ttttagtgcc cggaggatta
     3421 tgtttaatac aattagcaat caagttttca actgcgcgct ttaggtacct ttcatccata
     3481 ttaaaaagta tcttattgtg actggattct aaagcgaatc tcttattttc tgactccggt
     3541 agcaacttca ttttttctaa agtgtcatga attactttca ctacgttttt ttcttcaaga
     3601 tggattggaa gcgactcatt tttcaattga aaagttaagt tgaaatcttc aatcagcttt
     3661 tccatatatt cgacacgttc ttccattatt aaggaaaaat cacgcacttg ctgattttcc
     3721 cactcatatt catttgaaga taaaagaacc gtatatccct taataaccga aagaggggtt
     3781 tttaaatcat gtgagacacc ggccatccac tcttctcgtg tcttttccaa taattctctt
     3841 tcagccttat tcctttgaag cgttgaggta agttcagaca gagcctgcat taattcttga
     3901 taggtcttat atccagattt attatgtcta tatttgcttg aatgaaactt ccgatcataa
     3961 ggttcttcat atttttcttt agacaaattc tcaatccaag atacaataaa cagcagggga
     4021 gcacctagtt tttttccgta aaatattgca attacaatcc ctgccataat aatagaaaca
     4081 atccacaagt tattcaccca atagaaaaaa gggttatttt tttccatcgg ttttcccaat
     4141 acccatgtta aatcctgatt gtttttcgtt tcgtaccacg tagataattg ataacctttt
     4201 ttggcaggat acatgtaatc tgatattaat tctccaagaa tataatgctt aggtatattt
     4261 ttaggtttat taaaagaaaa aacctcatct ccttgttcat ctaaaatttg aatccacatc
     4321 cggttctcta ataaatcttc ttttgctttc gtgtttattg aaaattgttt atctgcaaca
     4381 actgtttggg caacaatttt tttcaaggat aattgtgggg tttccatttt attttgacct
     4441 aagacgaggc tgaaaaatat gatactgccc accatgagca gaccccaaat aaacatgagt
     4501 aaaaaaagtc tcgatacgaa gtaaaatgct atcctatttc tcagcttcac aataactcct
     4561 catctatagg ctctgcttca aatatatagc cctgtcctcg aactgttttt atccatcttg
     4621 gtctgctcgg gtcttcctct aatttttcac gtaatcgtct tacatgtacc attacagtac
     4681 tatctccgcc ataaaactcc ccccatacat ctttataaat ttggtgttta cttaaaattt
     4741 gattgggatg ttcacagaaa taaatcagaa gtttcatttc ctgagcaggg caatcgattc
     4801 ttgtcccgtt aacaacaagt cttccggtat tgggatctat tttaaagtat tcataatcgt
     4861 atacctgttt tagagggtaa gaagaagaga gctgagtcgt tctctttaat tgggctttta
     4921 cacgagctac gatttccagt ggattaaatg gtttagtaat atagtcatct cccccaaaac
     4981 taaacccttg caatttatct aaatctgttg tttttgctgt taagaagagt atcggcacat
     5041 ttgtatggga gcgtattttg ctgcataagg tgaagccatc agtgtccgga agcatgacat
     5101 ctaataaaat aatatttgga agttcctgat cgattttcag aagggtttcg ctccctgtca
     5161 tagctgtgga aatattgctg aaaccttcct tttcaaagca agttattaat aagtttaaga
     5221 tatgttcgtc atcatccacc atgaggattt tgttctcttc taaagtcata agttatcctc
     5281 ctttttattt cttattttat atgagatcaa ggacataaag gtcagaaaag gaaagaattt
     5341 aactttcgtt aagggttcag aatattcttt taatatttta accttgatat tcagggatca
     5401 atataactac atacagaaaa taaacaatgg atgtcgttaa gtgaatgttt aggaagagtt
     5461 tcgtttgtgt ttaaagaaca tcgcttatga taaaagtgag gtgagagaca aatgaatgat
     5521 caaatagtgg taacacacga tctaactaaa aagtataaaa agcatacttc agttgatgga
     5581 ttaaacttaa ggattaggcg cggcgaaatt tatggttttc ttggaccgaa tggtgctggt
     5641 aaaacaacaa ccatccgaat gttattaggt ttaattaaac caacaaaagg aaacatcgaa
     5701 atctttggcc aaaacctaaa caagaatcgt ttgcagatat tgcaaagaat cgggtcactg
     5761 gtagaatctc caacttatta tggtaattta accggttacg aaaacttaga agctgttagg
     5821 aggttaagag ggcttccgga acaacgggtc aatgaagtat tggaaactgt aaggttatct
     5881 aaagtagcaa atcgactgac taaggagtat tcccttggaa tgaaacaacg tttgggaatt
     5941 gcagttgccc tgttaagcag tcctgattta ttaattctgg atgaaccgac aaacggttta
     6001 gatccatccg gtatccaaga aataagagag ttaattaaag aattgcctaa atcgggaatg
     6061 agtgtcgttg tatccagcca cctgttgagt gaaatagatc aaatggctac tcaagtgggg
     6121 attataaaca atgggaggat gattttccag gactcaattg caagtttaca tcaaaaacga
     6181 aaaccactat taaaagtcgg tgttagtgac gtaatcgaag caaaaacaat actaaacagg
     6241 aaaggattaa aggttgattt acaaaaaaat tatttgtggc tgtctcaaac agaaccggaa
     6301 tttgtttcag aaatcaattc catacttctt cattcagggc tgtctgtatt tcgacttgaa
     6361 gaaaagacac gatcgcttga ggatattttt ttagaattaa ctggtacaga gggaagtcta
     6421 tgaaaaagtt attatgggca gatcaattaa aactgaaacg ttcgtcgtta ttgattgtag
     6481 tcttattggt tcccttactc attatagcat acgagttggt gaatcttact tatcgatctg
     6541 aatacgtgga aaaacaagct gaaatgttcc atgctgggtc aatgtggatg tatttactgt
     6601 atgataacag tttgttattt ggtctgggtt ttccattagc cgccacactt tctgcgtcaa
     6661 taatagcaaa tatagagcat caagcaaacg gatggaagca aaccctttct tttcccgtat
     6721 ctagaatgcg aatttatgta agtaaattta tttgcttagt agtcagttta tttatttcgt
     6781 caacaatctt cttgctcggc atggtactgc tgggcaaact ggtaggattc gaaggcagtg
     6841 taccttgggg acttttgttt ggagatagtt acagcatgtt agttacagta ctgcctataa
     6901 tggcattcca gatatggtta tctatggtgt ttagcaacca agcattctca attcttgtag
     6961 gatcagtatc atctataatg ggtttgtttt tggctgctgc tcaatcaacg agatggtttc
     7021 cgctggctta tcctagtcaa tcttcgacag tcattctgca gtatgaaggt ataggatata
     7081 acccagatct ttcatcttac ctttgcatta gccttttctt agggataatt atattatttc
     7141 taggctctat tcattttgct aaacgggatg ctttgtaaaa aggaggcgaa atacttgaaa
     7201 aacattttat ttgtagaacg tttaaaactt aggcgatcaa agttatggat catctattta
     7261 ctagggcctt tgttaggtgt atccctggca tacactaact ttattaaaaa ctataacctt
     7321 tttatgaatc ctggagacaa tccctgggta gaggcttgga cacaagtggc cttatttatg
     7381 ggcccttttg tattgcctat cgtagtggga attttcgccg cccttgtttg caggggggaa
     7441 catgtaggag gcggttggaa acagcttcta gccttaccag ttaaacactc agatatcttt
     7501 ctgggaaagt ttctaacagt ggtccgcatg atattcatta gtatgttcat tttaatcctc
     7561 ttatttattg gattcggtta tatgttaggc ataagcggga gtcttccttt acttacaatt
     7621 ctaggatatg gaattagagg gatcttagct tgtttaccat taattttatt gcagcttatt
     7681 gtttcaatca ggtctaaaac atttggcata ccactcgctg ttagcattgt ttttacatta
     7741 ccggccatta ttattgccag tacaccatta ggtcaagtat atccatggac acagcctatg
     7801 ttagcaatgt cacccgcaga tgaatcaccg attcaatcaa atttcctgtt ttactcaatt
     7861 atggtaataa cctgcctcgt tctcttggtt tacggaataa gaagttttac taaacgagac
     7921 cttacgtagg gtatatacgg tctaaactta tgagaattcg agacaaggta aactaatttg
     7981 actagcgcta tgtaaaacag aaatttatat gaaggtaaga ctaaatcttt ttggttgtat
     8041 tctttgaaac taaacgacta atggaaaagg tgatgtttca aggcataaga cataagaaat
     8101 ataaagatat cttaagactc tttatttaaa cattttttac atttaataat atctcttcca
     8161 ttttttgatt atgagttaat ataatactat acttaataag gggggtgaat acaatgagtc
     8221 aagaagctat cattcgttca tggaaagatc ctttttcccg tgaaaattct acacaaaatc
     8281 cagctggtaa cccattcagt gagctgaaag aagcacaaat ggataagtta gtaggtgcgg
     8341 gagacatgga agcagcatgt acttttacat tgcctggtgg cggcggtgtt tgtactctaa
     8401 cttctgaatg tatttgctaa tttgatttat ataggctgtt tcccttcaga aggaacagcc
     8461 tatattttat tatataaaat attagaaaat tcttaaaaaa caggagggta aatcgttggg
     8521 gaaaactctc gtttgttcag aaaatagcta tttccaagca tatatgaatc atttattaac
     8581 gccagatagt aatgaaataa taaatgttaa cacattggat gaattaaaac aaataatatc
     8641 caaggaaatt ttttcctctg taatcatcga tacttgccac cctaatgatt tagtgttgca
     8701 actgataaaa tcgatatctt gcccagtcat aatacttaac tccttagaaa ctaacgtttc
     8761 agattataac cctggtccaa tattaaatca aataaataat gtttcaaccc taaaacataa
     8821 tgtttttcaa ttgtctttta caactttttt cgacgttgga aagcattgta tttggaaaaa
     8881 gaatgaatat atccctctgg caatacaaga atttaaaatt ttatatttgc tttatttaaa
     8941 ttcaaataaa atagtctgtt ctgaataact tattgaatac gctgacctta ctggtaggtc
     9001 aagtctctat gtacacatta gttctcttag agaaaaagta gaggataatc ctggagatcc
     9061 aaagattctt caaacaaagt ttggaaaagg gtacctccta tctgacagta catatatttg
     9121 tcttgaaaaa aaagcagact caaaaaatgt tgtgtaaaaa ggatgaccca aaaatcattt
     9181 taaaatgact tttgagtcat cccatttatg ttagtgaggg gtgttttgtt ctttctctaa
     9241 accctttttc tattgctaat aaagctttgt cgggtgtaat tagaccacga ttaggttttc
     9301 ttgtacccgt cgcgatctca aacgccataa tttcaactgg gtcaataaca atatgcccat
     9361 cttttcttaa ttgttcaata ttcctggaaa caactgtttt attccacatt aaatcgttca
     9421 tattagggaa gaaaatagtg ttatgtggat gagctaatac agtagttgca actaaattca
     9481 ttgctatacc attagcagtt tgtcctaaga tgttcgctgt agctggaata atgcaatata
     9541 tgtccgccca gcggccaatt tctacgtggc tatgtctttt tccgttttcc ccatgttctg
     9601 agtatacatg gtcacaaaaa taagaaacag taggagctgg aataaggtct tccgctgttt
     9661 ttgtcataac aacccttgtt tccttaaaga aacttttaaa atataagaga tacgaggaga
     9721 tgccgacaga tgagattgat ccgcaaatcc cgatcaataa ctttttatct tttaatattg
     9781 aaatactcat tttttctcct cctgtaaatt ttaaactatc atactacaca attattcttt
     9841 ttgtggtgtt tatttcaaat attaaatatt cttaataaac acatataaaa taaacctaaa
     9901 cttcttttga aattctttta acttttaaat aaccctgcta tatttatgga taattaagga
     9961 atcttaattg ttcaaattta ttaaaaatga ggtgttcaat atgcatacaa aattaaaatg
    10021 gaattcggta tggaatagat cttcttcgat aagtgaaaga aaagtaaggc gtccacttaa
    10081 tactaattgg gatgaactaa caaacagacg cttcgaaaga tggaaaagcc ttgttgaaag
    10141 tgatgagggg attcgaattg agaatgtatt agccacccaa aatattgatg aagaaactct
    10201 aaagcatact atcaatgcaa aagaagtgga atttattaat gaaagtgatc atctaggatg
    10261 gctagaaatt attcagctag ttgatgaaca atcctataaa gatgtaaata tagaagttag
    10321 aaaagatatt ctcttcttta gttttataaa accatttttg aaaatagcaa gaggaaaatt
    10381 agaggaagta ttatattctc actctaataa atctctgata aaggaagaac ttagtccgtc
    10441 tgtaattgat gattcactta atattcttgg tgaaactttg tcagctataa gtagtcggat
    10501 attaatattg gagttaaatg tagcaagggt agcaggaaag ctccgaggtg aaacttctga
    10561 agaacgagcc tcttatttca ataaagtcct tttaaatgac ccggcatatg ttcgatcaat
    10621 tcgagaagaa tacatagttt taacaagact gttagcaaca aaaacaatgt attggattca
    10681 aaatacttct gaactcctta taagatttca tcaggataaa gggctattag aatctgagtt
    10741 tactaatggt caaaaattag gaaaagttat atccatcgat acaggaagta gcgtctcaga
    10801 tactcataac aaaggaaaaa cagtcgccat tttaaacttt gagactggaa ttaaaattgt
    10861 gtataaacct cgttccttag aaatagacgt aaaattcaat aagtttgtaa attatctaaa
    10921 tggtaaaaat ttaagttttg acttaaaaac tgtgcacaca cttaacaaaa aatcttatgg
    10981 atggacccag tttatctctt ataaagaatg tcaggaagaa ctgcaaattg gaaaatttta
    11041 ttggcgtatt ggaagttatt tagctatctt atatgcaatg aatgcggtag attttcatat
    11101 gcaaaattta attgctgagg gagaatatcc tattttagtt gatttagaat ctttatttca
    11161 taataattcc acgtatacag ataccagtgc ttttagtctc gcacaagaac atattgaacg
    11221 ttcagttttg cggattgggt tattaccgag aaaaataaat agtaaagctg gatttgaagg
    11281 aattgacctt agtgcattag gtgcacaaga aggacaagta tctccgcata aaaccagtac
    11341 aatagttgat cgagataaag atacggtcag gatagaagaa aaaaactttc caattccagt
    11401 tagtcaacat agacctatgc tgcatgggca aatcattaat agtgttgctt acgaaggaga
    11461 tattataaaa ggatttgaag aaacctactt ccttttcatg aaatataaac aagacatgct
    11521 cgaacaaata gattctttta aaggagttac tgtaagacaa atattgcgtg gtacatctcg
    11581 ctatgcaaac cttctgaaaa taagtttaca tccagatttc atgagagacg gcttagatcg
    11641 tgaaatgatt ttagataaat tgtggttaga taccaaattg aatccacgat tgaaccaagt
    11701 tgtaaatagt gaaaaggacg acttatttct tggggatatc ccatatttca caagcaagcc
    11761 tgaatctaca aatatgtggg attccaacgg tcgaaaaatc aacaattttt ttaaaacaag
    11821 tgccttaaat gagacaaagg aaaaaataaa tgaaatgaat gaaagtgact gtcatgaaca
    11881 agtaagcttt ataaaaacag ctattttagt aattaaggat tcttatcgta aacataaagt
    11941 atttgatata aatcctcgat tacacgtatt taacccaaaa gatttttttc aagaagctat
    12001 taaaattgga gactttcttg ctagtagggc gattgaaggt gaacagttag atggacaaga
    12061 ggatgtatct tggattggat cgtttgttga caatcaacga gaggatcaat tcaagatttc
    12121 agctgcaaat agttcattat acgagggtgt aggaggtatt tctctcttcc ttgcttattt
    12181 aggtcgcctc tctaacgatg aaaaatacac caaactatct aaaaaagctt tagtggcagt
    12241 acacaaaaat atgtctgcat ctagtgattt gggtgccttt ggggggattg cttcttacct
    12301 ttatttgttg gatcatttat caaaattatg gaatgatgaa caactattga aaaacgaact
    12361 tcattctgcc ctcaacaaat tagattcttt gatcgaaagg gatgaaaaca acgatatttt
    12421 aacaggggtg gctggaacag cagttatttt aataaatttg tttaaacggt ataaagaaga
    12481 acaaatctta aacttgatta caaaatgcgg aaatcgtctt attcaaaata ttaacgttat
    12541 ggaaaaggga gttggatgga aagtcccggc aaacccaacg ccagcctccg ggtttgctca
    12601 tggtgcctca ggaattatat gggctcttta tgaaatttac gcaattactg agcaaactgt
    12661 atttaaagag gtagctgaaa aagcattaga atttgaaaga actttgttta ttccggaaaa
    12721 aaacaattgg gcagatatta aacttgaaaa cggacagttt cgaaatgata attttgttgc
    12781 ttggtgtaat ggcgcagcag gcataggatt aggcagaata ttgatcctgc cacacaatca
    12841 aaatgaattg ataaaggatg aagcacatgt cgccattaat acaaccctaa aatatggttt
    12901 tgaacatgat cattctttat gccatggtga tttaggtaat ctggacatcc ttatgtacgc
    12961 agcggaaaac tttaataaaa agttaagcgt aaatgtaaca gaactaagcc ataaaatttt
    13021 aaatgatata aagctcagag gatggttaac tggatttgaa aaaaataacg aatccccatc
    13081 cttaatgatg gggtatgcag gtataggact tggattgctt aagatttttg caccgactga
    13141 agtgccatca gttttgagac tccaatcacc tttagaacta aaattgtaaa attaaaatga
    13201 gccttacttt gttaaggctc tatttcttag gagtgatcca atgagaagaa gagttcctct
    13261 agtaaggcaa atgggacaat atgagtgcgg gcccgcctgc ctcaccatga ttttaagtta
    13321 ctatgggagt actatatctc taaataaaat aagtgaacaa tgtgatgccc aaagaaatgg
    13381 cgtatctgta tccattttaa aatcagtatc agaatactat gggcttaact gcaaagtata
    13441 ccaagtttca tttaaagatt tgaaaaaata tatccattca tatcttccct gcatcatatt
    13501 ttgggatgaa cggcactttg tggttttaga acagattaaa aaaggtcttt ttcatataat
    13561 tgaccccaac agaggaaagt tgagattatc cgaagaagaa tttaaaagac attatagcaa
    13621 ggtaatcttg acttttacga agtcagatag atttaaagag atgatgccat cacccgcagc
    13681 aaagtattat ttacgttata tagttaaaag ccgtagtatt gtttcactta tcattctctt
    13741 ttcactgatc acacaagtag tcttcttagc cgttcctttt ttaattaaat atttagtgga
    13801 tcattcttta ataagtaaat caacaaattc ttttctattt ttaggaattg tagtcatcat
    13861 agcagttttt atattgggac ttgttatgtt tctccgcaat tatttcacaa ttaaacttca
    13921 agctattata agtaaaagca tttcaaacga ttttgtggaa catttattaa aattacctct
    13981 taatttttat gaaaatcgaa caaccggtga tattgcaatg agagtaagta acatttccat
    14041 tataagggag attatggcta agaatggagt aacagtagta ctagatatta ttactttgat
    14101 ttcatttttt attgctatgt taactcaatc atttaagctt gcattttttg ctattggatt
    14161 ggcaattatt caattcttac taatgatgat tttgattcca agaataaaaa atttaatcca
    14221 taatgactta tcaattcaaa caactacaca aagttttttg gtggaagctc taagagctat
    14281 cacttttatt aaatcaaatg gtttagatca ttctatccta acaaagtggt caaattacta
    14341 tgataaacaa atcgaagcat tttcacagcg ataccactta gacgctataa tggatagcat
    14401 aagtataagc atccgatatt gtgcacccct tctcttatta tggtttggat caaaagaagt
    14461 tatcaccgaa aatttaacac tcggaggctt attagggttt agcagtttag gaacatcttt
    14521 attgttgccg attgcttctt taataacaag catgcaacaa tttcaattgg tcggtgacac
    14581 ttttgaacga atgcaagatg ttatggaaac tgagcccgaa caactcaacc aaacttcaat
    14641 aattgaaact gaactatcaa aacaggacat aaaacttgaa aatgtcacat ttacgcacca
    14701 gagcttacat attcttaaag aagtttcatt aaacattaag tcaggtacta aattagctct
    14761 ggtaggccgt acaggtagtg gaaagacaac tttatcaaga attatactgg ggttatacaa
    14821 acccactaag ggaaaagtat tatatggtga agaagacttg aagaatttaa acctttacga
    14881 gctccgaaaa caaatggggg tcgtattaca agaaagcttt cttttcaatg atactattgc
    14941 aaacaatata gctggattta aaagcttatc tcaagataaa attgaacaag cagcaaagag
    15001 agtgcagtta cacgaagata taataagaat gccaatggga tataacacaa ttatcgggga
    15061 aaatggcagt atgttgtcag gagggcagcg tcagcgcata gcaatagcaa gagctatcgt
    15121 cgataaccct tctgtagtca ttttagatga aataacaagt aacttggata cattaacaga
    15181 gcataaaatt gacgaatact ttgcaaaatc aaatattacc cgtattgtaa taactcatcg
    15241 tcttttaagc agccaagact ctgatttaat agtggtatta gatcaaggaa aaatagtcga
    15301 aaaaggaaaa catcaagagt tattagagaa aaggggatat tattatgact tatggataaa
    15361 acaagtaggg gatagacaga aagctacgct ggaaaagccc cttttcctca atgaacccac
    15421 tggaaaaact ttgggccgct gactttattt tatttcaata acgcgtgcta taccctttat
    15481 ctccatgttc gcagactaca atttgaaaga ctgaaacaaa acaagccaga gcaatccccc
    15541 atttagaaaa aatcttgccg ctgtcgaaca taaccatgtg tttatcaatg actttgacac
    15601 catctacctt taccaatcgc tctcagtcag caacaggttg atttgattgt gatactttgg
    15661 tgaaacgcaa gaacgaaata accggaaaga cgaaagcact cacgatgttg tgagtgcttt
    15721 ttcttcagcc gacctgctgt tttacggctt taccggctga tccgaactct ctcattttgc
    15781 ttcgcaccgt ctcttccacg gcttcaatgc cgggtgtcaa atagccgcgc ggttcgtaca
    15841 gatcgctgtt ttcctgaaac atgcggcgtg tttcgtctgt ccacgctacc atacattccg
    15901 tattgatatt gatcttcgcg tggccgagcg tgatggcttt tttgatctga tcctgcggaa
    15961 tcccggatgc cccgtgaaga acgaggggaa tatcagtcat gcgggagata gcctccattt
    16021 ccttaaatcc gagattcggc tcaccctgat atttaccgtg aacagagccg agggcggcgg
    16081 ccagcgcgtc gatattggtt tctttgacga tccgctcaca ttccgtgata tcggcatagc
    16141 agacccctcc gaccagtccg tcttccattc cgccgaccgt gccgacttcg gcttctactg
    16201 acacgccgtg tttcgcggca taatcggtga cttcttttgt catcgcgata ttctcttcaa
    16261 tcggctgatg ggagccgtca atcatcactg agctgaatcc ggcatcaacg gcctgtctgc
    16321 agcgttccgc actgctgccg tgatcgagat gaagcacgac cggaacggta atcgccatgt
    16381 cctccattaa cgcgccgacc atggcggcaa ttgttttaaa cccgcctaaa tagtcgacca
    16441 gacgatcgga agccgcggcg atgaccggcg attgctcttt ttgcgccgct tgcagaatcg
    16501 ccttcgtcca ttggaggccg ttgatattaa actgaccaat tgcatattgc tcccgctttg
    16561 catcttcaag aagctctttc atcgatacaa aagccatatt cacccctcct ttatccatta
    16621 catgctgaag tattttgata cgacatccac tgttgttttt ttcgctgttt gaatggcttc
    16681 ctcagcagtc agcttatagt attcaggccg gaagagctca accgaaacaa catcagagaa
    16741 gccgatttcc ttcagtgctg ataagtgggc atctaagtca attgcccctt gtcccggcca
    16801 tacacgatcc tcatctgtta aaaagccgat tgggaaatct tctgtatcat caatatgata
    16861 gatgaagatt ttctttccgt ccgcctgctt taagctctca atatttgaac ccattgcatg
    16921 gaagtgaaaa ctgtcaagga caagcccgac attgtcacgg ttaactgtgt ttacgatctc
    16981 atacgcctgt tcaaacgtat tgaccgtaca ttgcggatgg ccgacaaatt caagcgctat
    17041 ttttacgccg tacggctccg cgatatctga cagctcagtc agcacgtcta cactgctctt
    17101 tttgatctct tcttttataa tcttctgctc tgtcacaagc ggaacggcca ccacatattt
    17161 cacaccgagg gttttgcatg tttccatcat gcctttaaat tcagtgatga tctcgttgtg
    17221 gcccttttca tcacggttgt tgaagaaaac gagcgcgttt aaggcaagcg gtttgatgtg
    17281 atgggtttga aaatattccg caagatctgc caatgaatga tcttttaagt actccggcag
    17341 cttatccatt gtgcggattt caatataatc atagccgtgc ttttcgcata attctaaatc
    17401 ctgtttaagg tttgagtttt ccaatgttgt cgcttcatta aaacaaagtt tcataccaga
    17461 ctcccccatc tgcgttttag atatgaaggg agttcggcag gaaggctgtc gccatatccc
    17521 gccgaactcc atgctcagct tatgccagac ctaattcttc tttcattttc ttaagcataa
    17581 atcggcttga ttcatccgct ctttcatcga cccaagcaaa tacggcattc gtcgcaattc
    17641 cgtcgaactt catctctctc agttttctga aaatcgtatc aaaatcaacc tcgccttggc
    17701 caatgtccaa atgctggtga accgttactt tcgcgtcagg cggattgacg atgtagcgaa
    17761 ggccatgagc cgctttatga ttataggtat ctgcaaataa aacatgtgtg aggcggtcgc
    17821 cggcttcgtc aaacatggtc tcgatgtcgc ctttgccgtc atcatagaag aacgtatgcg
    17881 cagtcgagta gacaagattg atccaatcct tgtcaagcgc gcggatcata tccatcgcac
    17941 ctttgtgcgt ttcgataaaa tcgtatgggt gggcttgaag attgagttta ataccttctt
    18001 tttcaaagac tggcagaagc tcatccatgg atttgataaa tttttcttca cttgttaaag
    18061 gatcatattt tgaaccgctg aattcgctgt tcatcaaatc cacttcaagt tcaaccgcaa
    18121 tttcgattgc ccgtttccaa ttgcgcaccg ctgcctgccg gcggtcttca tcaggacccg
    18181 cccagtggta aagaggaaga agcgatgaaa gcttaacacc tgtatctctt aaaaggcgct
    18241 ttaattgttt gatctttgct gaatcgactt tcggatattt ataaaacggg caaaaatcct
    18301 cgcgcggaga caattcaata tgttcatagc cgagctccgc cgttttatag accgtttcct
    18361 ctaaagttaa atcatcacga tacatggatg gatccaatgc taacttcata ttttcactcc
    18421 tctgtttttt agttttgaac tgttgtaaaa gattgataga attccggttt ttccttcaat
    18481 tcaacctttt ctttttgtcc ggattcctgg gccttcacac aagcatccgt tgtaacagcg
    18541 gcaatatagc cgtcccatgc cgtcggtccg ctgacctcgc ctttcttttg aatcgaatca
    18601 ataaagtctt ggatttccac atcgtacgca gcgacaaagc gtctctgcca atccatcaga
    18661 atatctgtgc tgaatttgcc ttcttttctc aagctgatgc ttgatggctc gggaagcttg
    18721 atgatgccgt cttctccgac gatttcacat tgaatgtcat agccgtattt acagttcaca
    18781 tagatttcag cattgatgac gataccgcct tttgtttcaa tcacgacgat ttgcggatct
    18841 tttaaatgcg gcagcgcgtt tttcgatttt ttcgggtaga tgacttgaac ggactcgtag
    18901 tcatcgttga cgagccagtg cagcacatca atttcatgaa caagcgtgtc gactacggcc
    18961 atatcggttg tgtagttatc tcctacagtc gggttgcggt gcgcgcaatg aatcataagc
    19021 ggttcgccaa tcacatggtt atcgagtgct tccttcagct gtacgtaacc gctgtcataa
    19081 cggcgcatga agccgacttg aacaaggcgt ttgcccactt tgatttcttc ttcgacgatg
    19141 cgcatgcatc cttcagccgt tgtcgcgagc ggtttttcac agaacacata tttctgggct
    19201 ttaatcgctt tcagcacgct tgactcatgc gcaggccccc agcttgtcac taagacagcg
    19261 tctacatttt cgtctgcaag caggctgtca tcattcggat aaaccgtcgc gtttaattgg
    19321 tattgctcaa cgaccttttg agcagcttct tgattaacat ccgttacagc tacgatttct
    19381 gcgccggaca gcttattcgt gatgcggtta atatgttctt ttccgattgc tccagttcca
    19441 attacgccaa tacgtaaact cattgacagc cactccttct gttggttaca tgattttgct
    19501 ttctgttcct tgctttactt gactctgagg agatccgtag agttcctctt gtatttgttc
    19561 aagcgacttg ccagaggtat tcggcgcaaa gagcagcccg ataatcatac tggccgtcac
    19621 acatccgaga agaattgcag ccattgttcc aatgccgaaa ttggtgataa tcattgggac
    19681 aaacagactc caaatcccta ttgaaatacg gacaaggaaa aacatcagtc cttgtgcgga
    19741 agcacgatat tgcgtaggaa agatttcgct ggcccataac tgatagttcg cttgctgccc
    19801 tgctccgtta ttgatgccaa tcacgacaat aaacaggagc agaatcggca ggccttcaac
    19861 tggcagcaga aacagtgtcc acccgatcac cgccatgaaa gcggcgattc caaatacggt
    19921 ttttctatat ttgtcggcaa agggcttgaa gatcaaggcg acccccaatc ctgtgaagat
    19981 aaacagcccc atttgcaaaa ggttggccat gttggcagat acaccgccga cctgctgata
    20041 aatgtatggc ataaagaagc ccatgacccc ggcggctagg ttccaaacca agtacacacc
    20101 catcaaaaac aggatgcttt ttagatacat aggcttgagc aaatcaaaat acgatgtctt
    20161 attcagtaca gccggcttct ctgcctgagc atcctccggc tgattttttg tctgccaggc
    20221 gtctgattcc ggaagcctga ttctcaggat gtacgtaatc agcgcaatca caagcagatg
    20281 ggcaaatacg attttattcc ccaagagtcc caagtcaccg gccagtacgg agaggagcag
    20341 tacaacgaca gcgcccgcgg cccaagcgac ttgtgctacg ccgcaatgcc tggcccgatt
    20401 cttctttggc gcattttccg caataatggt ccatgacgcg gttatgtcag cccctactga
    20461 taaaccgata atgatgtaac cgcttaacaa catggggaaa ttaaccccga acaaaaccaa
    20521 acaaatccct agtgcataaa ccagcatact attggtataa acagccttcc gtccgacttt
    20581 atcagccaga aacccgccaa gcagcgcgcc gacagcggca gaaatcgcat tcgcgctcag
    20641 cgcgccgagc agccgatttg tgtatcggat agcttaaggt aactgaccca taatgataaa
    20701 ccggcggagc ctgccacaat tgaaccggca tcaatatagt tggccaatgc tgccgcgatt
    20761 gtccgtttat tgaaggctga atctccattg gtattgccca tgtgttcatt ccccattaag
    20821 ccagatccaa caactgctga tcaatatagt ttctcgcgat caatgcatac tccagcgggt
    20881 ttgcaacatc ggggtcctgt tcagcttcaa tgacaatcca tccggaataa ctgtgcttca
    20941 acagcagctg atatacttct ctaaagtcaa tgcagccgtc accgggaacc gtaaacatgc
    21001 cttttaaaaa tgattgccgg aacgattgtc cttcgagcct gcattgttcc atgacattca
    21061 ggcgggcatc cttaaagtgc acatgcttaa tgcggccgat atgcttctca agcatcccca
    21121 tgtaatcgcc gtcagaaata tacgcatggc ctgtatcata gaggaggtgt acatgcgaag
    21181 ggtcagttcc tgccatcagg cggtccactt cttccgctgt ttggacacca gtgccgagat
    21241 gatgatgata gacaagcttc aagccatgct gagcggcaat ttcgccaagg tgattcagcc
    21301 cttcgcaaag ccgctcccat tcatcatccg taaagtgcgg cttctctgtg aacacgtttt
    21361 tctccaagct ttgcacgctg tacgtttgtt cagagacaac tgcgacatcc gcgtttactt
    21421 gctgcaaata ctcacaatgc agggtaaatg tctttgccgc ttcaccaagt ccgtcacgca
    21481 aaataaaact gctgaaccat tttcctgcaa tgcgtaagtt ccgaagcttc agctctttgt
    21541 tcaggatggc aggttcgggg aaaaagcccc cgacctccgt gccttgaaaa cgcgcgacaa
    21601 cgatatcact taacaaatgc tgaagtgtat ttcccgctcc aatttcaggc atgtcatcat
    21661 tccgccaccc aatgggagcg attccccaca ggatttcatt tttgcccatc tatggtgcct
    21721 cccctctaat actgcttcgc agattccagc tttttctctt ttgcttcgta tgccttctga
    21781 acgctttctt gttcagatac ctctgccacc ccgacatgcc accagctgtc atagccgtcc
    21841 gtcattgttt taggcagcac cttcatttca attaatgttg atacatcctg tttcttcgca
    21901 tcctctaacg cagcttttaa ttcttctact gtgtttgcgc ggtaggtttt cgcgccgtat
    21961 ccctcagcga ctttcgcgta atcgacattc aggatttggt tgtcatctgt gcggaactcg
    22021 caatagtagc tgccgctgcc gtgatccatt tgcaggttgt tgatgcatcc gaatcctgag
    22081 ttgtcaaaga gcagcacatt gattttcttg ttgtactgaa tcgccgtgat cagttcagaa
    22141 tgaagcatca ggaagctgcc gtctccgacg atggaataca cttctctgtc agggtgggcc
    22201 agtttaagac cgagtgtccc ggacacttca tagcccatgc aagaatatcc atactccagg
    22261 tgatacgtat tcggaacttt agaatgccac aaacgctgca aatctcctgg gagtgagcct
    22321 gctgaacaga tgatgacgct gtcttcagga atcgtctcgt tgattgtcag caatgctgtt
    22381 gtttgcggaa gctccgtatt caacgcgtca gcatattcat tcaggacctc ttgagaaaag
    22441 tgatgtttga tttccggatc aaacgcttcc cgcttaaacg tcactttgct gagacgctcg
    22501 cgttcagcta gccattcgtc cttcagctcc cggatcgttg tgccgaactc gctctcatag
    22561 ccttcaagca agccgtgcag tttgccaagc gtcactttcg catccgccac cacttggaat
    22621 gcatcaagtt tatacgcctg cattcggctg acgttaatgt tcaaaaactt cgctttatca
    22681 aaatcaaaag cggtcttaga ggatgtcgca aaatctgtat accttgtgcc gatgccgata
    22741 atcaaatcag cttggcgggc cgctttgttt gccgcaagtg tacctgtgat gcccattccg
    22801 ccaaggttgt tcgcaaaatc tgcctcaaca gtagactttc ctgcctgcgt ttcaactaac
    22861 ggaatgttat aggcttcaga aatggcaacc aattcatcgc gcgcaccgga atattttgcg
    22921 cctccgccga cgagaatcac aggttttttg ctggatttaa tcagctccgc cgcaccttga
    22981 agctcgcgct cgctcggctg catgcgatca atatagtgaa cccgtttgac gaagaaactt
    23041 tcatcaaaat cgtatgcttc cccttcaaca tcctgagaaa tacaaatcgt tgccggacct
    23101 gcttttgccg gatcagtcat gacttcaaac gcgcgcagca aactgctcat cagctgctca
    23161 gggcgcgtaa tgcggtccca gtatctcga
//
