LOCUS       NZ_CP032855            21612 bp    DNA     circular CON 22-JUN-2024
DEFINITION  Bacillus subtilis subsp. subtilis strain PJ-7 chromosome, complete
            genome.
ACCESSION   NZ_CP032855
VERSION     NZ_CP032855.1
KEYWORDS    RefSeq.
SOURCE      Bacillus subtilis subsp. subtilis
  ORGANISM  Bacillus subtilis subsp. subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 4293706)
  AUTHORS   Kim,S.-J., Heo,J. and Kwon,S.-W.
  TITLE     Genome sequencing of strain PJ-7
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4293706)
  AUTHORS   Kim,S.-J., Heo,J. and Kwon,S.-W.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2018) Agricultural Microbiology Division, National
            Institute of Agricultural Sciences, 166, Nonsaengmyeong-ro,
            Iseo-myeon, Wanju-gun, Jeollabuk-do 565-851, Korea, Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: MAR-2018
            Assembly Method                   :: RS HGAP Assembly v. 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 222.0x
            Sequencing Technology             :: PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003665215.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:29:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,711
            CDSs (total)                      :: 4,590
            Genes (coding)                    :: 4,234
            CDSs (with protein)               :: 4,234
            Genes (RNA)                       :: 121
            rRNAs                             :: 10, 10, 10 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 10, 10 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 356
            CDSs (without protein)            :: 356
            Pseudo Genes (ambiguous residues) :: 0 of 356
            Pseudo Genes (frameshifted)       :: 219 of 356
            Pseudo Genes (incomplete)         :: 131 of 356
            Pseudo Genes (internal stop)      :: 56 of 356
            Pseudo Genes (multiple problems)  :: 44 of 356
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:07:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1676702
            Orig. end                         :: 1698314
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032855.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            This genome has a base modification file available.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21612
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="sactipeptide"
                     /region_number="5"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     cand_cluster    1..21612
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21612
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11612](+)"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11612
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     gene            complement(32..1171)
                     /gene="acdA"
                     /locus_tag="D9C11_RS09125"
                     /old_locus_tag="D9C11_09125"
     CDS             complement(32..1171)
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /gene="acdA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391598.1"
                     /locus_tag="D9C11_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09125"
                     /product="acyl-CoA dehydrogenase AcdA"
                     /protein_id="WP_069837822.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.2e-40, bitscore:
                     136.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.9e-26, bitscore:
                     89.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.5e-52, bitscore:
                     175.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFSLSEEHQMIRKLVRDFAKHEVAPTAAERDEQERFDRELFREM
                     ANLGLTGIPWPEDYGGIGSDYLAYVIAVEELSKVCASTGVTLSAHISLCSWPLFAFGTE
                     EQKTEYLTQLALGEKIGAFALTEARSGSDAGSMKTTAERIGDDYVLNGSKVFITNGGVA
                     DIYIVFAVTDPEKKKKGITAFIVEKDFEGFFTGKKEKKLGIRSSPTTEIMFEDCVVPAS
                     KRLGQEGEGFKIAMKTLDGGRNGIAAQAVGIAQGALDAALQYAKERKQFGKSIGEQQGI
                     AFKLADMATMIEALRLLTYQAAWLESSGLPYGKASAMSKLMAGDTAMKVTTEAVQIFGG
                     YGYTKDYPVERYMRDAKITQIYEGTQEIQRLVISRMLAD"
     gene            complement(1168..3285)
                     /gene="fadF"
                     /locus_tag="D9C11_RS09130"
                     /old_locus_tag="D9C11_09130"
     CDS             complement(1168..3285)
                     /codon_start=1
                     /gene="fadF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391599.1"
                     /locus_tag="D9C11_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09130"
                     /product="heterodisulfide reductase-related iron-sulfur
                     binding cluster"
                     /protein_id="WP_088272547.1"
                     /transl_table=11
                     /translation="MSGFLIANTLLFLIVTAYAVYLFVYLVKTRLAYIKLGQKEQFDQR
                     FKERLHDIWVNVFGQKKLLKDKKSGIIHVMFFYGFILVQFGAIDFIIKGLAPGRNLPLG
                     PVYPAFTFFQEIVTFLILIAVGWAFYRRYIEKLVRLKRGFKAGLVLIFIGGLMLTVLLG
                     NGMNLIWHEHGLSWSEPIASGIAFMLSGVGKTGAAVIFYIAWWIHLLFLLSFLVYVPQS
                     KHAHLIAGPANVFFNRMESAGKLEKIDFTDETKESYGAGKIEDFRQSQLLDLYACVECG
                     RCTNMCPATGTGKMLSPMDLILRLRDHLTEKGAAVTSRSPWVPAAAFRHTRGNQLAAAS
                     AGSGSQEAAAALDYNPSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVDKIIDLRRYLV
                     LTEGKMDSDAQRAMTSIERQGNPWGLNRKERENWRDEAPDAEIPTVKEMKKEGKEFEYL
                     FWVGSMGSYDNRSQKIAISFAKLLNHAGVSFAILGNKEKNSGDTPRRLGNEFLFQELAE
                     KNISEFEKNDVKKIVTIDPHAYNLFKNEYPDFGFEGEVYHHTEVLAELVKNGKLKPQHP
                     LHETITFHDSCYLGRYNEVYDPPREILKGIPGVQLVEMERNRETGMCCGAGGGLMWMEE
                     ETGNRINVARTEQALAVNPSVISSGCPYCLTMLGDGTKAMEAEDQVKTYDVVELLAQSV
                     LGADLKMGEKQ"
     gene            3440..4636
                     /gene="cls"
                     /locus_tag="D9C11_RS09135"
                     /old_locus_tag="D9C11_09135"
     CDS             3440..4636
                     /GO_function="GO:0008808 - cardiolipin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0032049 - cardiolipin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cls"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391600.1"
                     /locus_tag="D9C11_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09135"
                     /product="cardiolipin synthase"
                     /protein_id="WP_017696271.1"
                     /transl_table=11
                     /translation="MKVFIVIMIIVVIFFALILLDIFMGRAGYRKKAYEPVFSKKKSDI
                     ELIHCGADLVERMMKDIRQAASSVHMMFFIMKNDEVSHNMYTLLKAKAQAGVSVYLLLD
                     WSGSQKIKKPALQTMKNAGVQVHFLNKPRFPFFFFHMQKRNHRKITVIDGKIGYIGGFN
                     IAEEYLGKKAKFGNWEDYHLRMKGEGVHDLQTVFASDLKRNTGIELGSEVWPKLQQGTI
                     SHKIYATDGYSLENKYLANIAQAKNRLTVCTPYYIPSKPLQEALINARKNGVSVRIIVP
                     MKSDHPLVREAAFTYYSELLDAGCLIYRYYQGFYHVKALIIDDHLSIIGSANFDKRSLF
                     LNEEVNVEIDDEAFTSEVYATIEEDMKKSERLTMEDFSKRTFRQRPAEWLGRALSYFL"
     gene            4649..5611
                     /gene="uvsE"
                     /locus_tag="D9C11_RS09140"
                     /old_locus_tag="D9C11_09140"
     CDS             4649..5611
                     /GO_function="GO:0004518 - nuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0009650 - UV protection [Evidence IEA]"
                     /codon_start=1
                     /gene="uvsE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391601.1"
                     /locus_tag="D9C11_RS09140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09140"
                     /product="UV DNA damage repair endonuclease UvsE"
                     /protein_id="WP_121591249.1"
                     /transl_table=11
                     /translation="MIFRFGFVSNAMSLWDASPAKTLTFARYSKLSKTERKEALLTVTK
                     ANLRNTMRTLHYIIGHGIPLYRFSSSIVPLATHPDVMWDFVTPFQKEFREIGELVKTHQ
                     LRTSFHPNQFTLFTSPKESLTKNAITDMAYHYRMLEAMGIADRSVINIHIGGAYGNKDT
                     ATAQFHQNIKQLPQEIKDRMTLENDDKTYTTEETLQVCEQEDVPFVFDFHHFYANPDDH
                     VDLNVALPRMIKTWERIGLQPKVHLSSPKSEQAIRSHADYVDANFLLPLLERFRQWGTN
                     IDFMIEAKQKDKALLRLMDELSSIRGVKRIGGGALQWKS"
     gene            5692..5964
                     /locus_tag="D9C11_RS09145"
                     /old_locus_tag="D9C11_09145"
     CDS             5692..5964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391602.1"
                     /locus_tag="D9C11_RS09145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09145"
                     /product="hypothetical protein"
                     /protein_id="WP_003227597.1"
                     /transl_table=11
                     /translation="MKNIKSLKVAAQAFTLRNLIHLYKMCHSGSHEVYIYSKKTMCKIK
                     SLIELETFRMAHNEKEYLIVVEGTKASQLIEKFQNLIEPAEREAL"
     misc_feature    complement(6056..6072)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.82"
                     /tool="antismash"
     gene            6101..7449
                     /locus_tag="D9C11_RS09150"
                     /old_locus_tag="D9C11_09150"
                     /pseudo=""
     CDS             6101..7449
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611967.1"
                     /locus_tag="D9C11_RS09150"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09150"
                     /product="IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MFHTRNSSQNTAEFVLLDQLVEEDHLLRKIDKHIDFSFIIEKVKP
                     YYSENKGRPSLDPLILFKMMFIGYLYGIRSERQLEKEIYYNMAYRWFLGLNINDPVPHH
                     STISWNRRTRFKDTTIFQDIFDEIVLQAINHDMVGGRVLFTDSTHLKANANKHKYTRKT
                     IAQDTQNYIKDLNEAIQEDREEHGKKPLTAKEEVKAEKEIRHSTTDPESGYLYRENKPE
                     GFFYLDHRTTDMKYNIITDAYVTPGNVHDSVPYLDRLDHQIARFGFQVEAVALDSGYLT
                     TPICKGLSDRQIFGVIAHRRYHPIRGLFPKWKFHYDSEQDRYICPNHQTLTYSTTDRKG
                     YRSYKSNPEICSSCPLLENCTKSKNRQKVITRHVWEDHKEKVRQNRLSVSGKNLYKKRK
                     EKIERSFADSKQLHGLRYCRLRGKRNVSEQVLLTAACQNMKLPHT"
     gene            complement(7591..9261)
                     /gene="argS"
                     /locus_tag="D9C11_RS09155"
                     /old_locus_tag="D9C11_09155"
     CDS             complement(7591..9261)
                     /EC_number="6.1.1.19"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004814 - arginine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006420 - arginyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391614.1"
                     /locus_tag="D9C11_RS09155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09155"
                     /product="arginine--tRNA ligase"
                     /protein_id="WP_003227570.1"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     gene            complement(9258..9686)
                     /gene="ywiB"
                     /locus_tag="D9C11_RS09160"
                     /old_locus_tag="D9C11_09160"
     CDS             complement(9258..9686)
                     /codon_start=1
                     /gene="ywiB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391615.1"
                     /locus_tag="D9C11_RS09160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09160"
                     /product="DUF1934 domain-containing protein"
                     /protein_id="WP_014481216.1"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFVKGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     misc_feature    9893..9908
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            10001..10132
                     /gene="sboA"
                     /locus_tag="D9C11_RS09165"
                     /old_locus_tag="D9C11_09165"
     CDS             10001..10132
                     /GO_process="GO:0019835 - cytolysis [Evidence IEA]"
                     /codon_start=1
                     /gene="sboA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391616.1"
                     /locus_tag="D9C11_RS09165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09165"
                     /product="subtilosin A"
                     /protein_id="WP_003222002.1"
                     /sec_met_domain="Subtilosin_A (E-value: 9.8e-29, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       10001..10030
                     /prepeptide="leader"
                     /note="peptide class: sactipeptide"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="D9C11_RS09165_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       10031..10132
                     /prepeptide="core"
                     /locus_tag="D9C11_RS09165_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="33.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[10000:10030](+)"
     gene            10089..10241
                     /gene="sboX"
                     /locus_tag="D9C11_RS09170"
                     /old_locus_tag="D9C11_09170"
     CDS             10089..10241
                     /codon_start=1
                     /gene="sboX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_054594.1"
                     /locus_tag="D9C11_RS09170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09170"
                     /product="bacteriocin-like protein SboX"
                     /protein_id="WP_010886632.1"
                     /transl_table=11
                     /translation="MKLPVQQVYSVYGGKDLPKGHSHSTMPFLSKLQFLTKIYLLDIHT
                     QPFFI"
     gene            10266..11612
                     /gene="albA"
                     /locus_tag="D9C11_RS09175"
                     /old_locus_tag="D9C11_09175"
     CDS             10266..11612
                     /codon_start=1
                     /gene="albA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391617.1"
                     /locus_tag="D9C11_RS09175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09175"
                     /product="subtilosin maturase AlbA"
                     /protein_id="WP_121591251.1"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1079.9, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 5.5e-29,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.6e-07, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.9e-44, bitscore:
                     150.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3e-06, bitscore: 24.9,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8.5e-22, bitscore: 76.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 5.7e-10, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.8e-09, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRAIR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFNN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIIHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     aSDomain        10281..10556
                     /aSDomain="Subtilosin_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a subtilosin
                     sactipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_D9C11_RS09175_Subtilosin_rSAM_RRE.1"
                     /evalue="3.40E-31"
                     /identifier="RREFam018.1"
                     /label="D9C11_RS09175"
                     /locus_tag="D9C11_RS09175"
                     /protein_end="97"
                     /protein_start="5"
                     /score="98.4"
                     /tool="antismash"
                     /translation="MFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLNKTAYE
                     LCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQ"
     gene            11625..11786
                     /gene="albB"
                     /locus_tag="D9C11_RS09180"
                     /old_locus_tag="D9C11_09180"
     CDS             11625..11786
                     /codon_start=1
                     /gene="albB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391618.1"
                     /locus_tag="D9C11_RS09180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09180"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbB"
                     /protein_id="WP_003222006.1"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     gene            11783..12502
                     /gene="albC"
                     /locus_tag="D9C11_RS09185"
                     /old_locus_tag="D9C11_09185"
     CDS             11783..12502
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="albC"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391619.1"
                     /locus_tag="D9C11_RS09185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09185"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_014481218.1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEAFHFSKYINRRISELSLGNRQKVVLMTGLLLRAPLFILD
                     EPLVGLDVESIEVFYQKTREYCEAGGTILFSSHLLDVVQRFCDYAAILHNKQIQKVIPI
                     GEETDLRREFFEVIGHE"
     gene            12495..13805
                     /gene="albD"
                     /locus_tag="D9C11_RS09190"
                     /old_locus_tag="D9C11_09190"
     CDS             12495..13805
                     /codon_start=1
                     /gene="albD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391620.1"
                     /locus_tag="D9C11_RS09190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09190"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbD"
                     /protein_id="WP_121591252.1"
                     /transl_table=11
                     /translation="MNNIIPIMSLLFKQLYSRQGKKDAIRIAAGLVILAVFEIGLIRQA
                     GIDESVLRKTYIILALLLMNAYMLFLSVTSQWKESYMKLSCLLPISSRSFWLAQSVVLF
                     VDTCLRRTLFFFILPLFLFGNGTLSGAQTLFWLGRFSFFTVYSIIFGVVLSNHFVKKKN
                     LMFLLHAAIFACVCLSAALMPAATLPLCAVHMLWAVVIDFPVFLQAPPQQSRMHSFMRR
                     SEFSFYKREWNRFISSKAMLLNYAVMAAFSGFFSFQMMNTGIFNQQVIYIVISALLLIC
                     SPIALLYSIEKNDRMLLITLPIKRKTMFWAKYRFYSGLLAGGFLLVVMIVGFISGRPIS
                     VLTFLQCIELLLAGAFIRLTADKKRPFFSWQTEQQLWSGFSKYRSYLFCLPLFLATLTG
                     TAVSLAVIPIAGLVIVYYLQKQDGGFFDTSKRERLGS"
     gene            13795..14955
                     /gene="albE"
                     /locus_tag="D9C11_RS09195"
                     /old_locus_tag="D9C11_09195"
     CDS             13795..14955
                     /codon_start=1
                     /gene="albE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391621.1"
                     /locus_tag="D9C11_RS09195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09195"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbE"
                     /protein_id="WP_121591979.1"
                     /sec_met_domain="Peptidase_M16_C (E-value: 8.4e-05,
                     bitscore: 20.7, seeds: 139, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVNLLKTHQFSTISIAASFLKPIESAAEPEEETIYFYGAAAYLK
                     EQIIDDFGCAAGSRFMYSANLFFDQQLKTCGTRLIHPLYNGNLHVDALMKTFADLSFPS
                     SLSFEAVEKARNELLLKIEKKFTDPFSYSAARLAEEVFGNPMYGTGMFGRKDRIKAIHP
                     KRFHDATDFIVDLASQQKQLNILGQVQACDVRGHAPQTSAVTSERIPVNRHVFETETRS
                     AAGPSVLTLGFDCGEMKDASDYIKIQLIDGLLGKYGHSALFKHFREKDLAVYHVIIRYD
                     VMNNLLLVSICTDQLHEIDIPPRVLEAVSAFHTDERELEQAKQFLRNELLLQFDSPEGL
                     LAYMGILRRFSCTKEALLDGISAVTCRDVLQFIATINYIGAHVVRG"
     gene            14960..16240
                     /gene="albF"
                     /locus_tag="D9C11_RS09200"
                     /old_locus_tag="D9C11_09200"
     CDS             14960..16240
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="albF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M16"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391622.1"
                     /locus_tag="D9C11_RS09200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09200"
                     /product="pitrilysin family protein"
                     /protein_id="WP_088272550.1"
                     /sec_met_domain="Peptidase_M16 (E-value: 2.7e-13, bitscore:
                     48.2, seeds: 24, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKAFFQQLDERTDIRYTDSGLKIFRLKFPRAHLRLCNVKIDFG
                     SRDVCIRAESGDTLLPYGTAHFLEHLLFWHNGRNLYSDFFAHGALLNAFTTYTDTNFMF
                     TSLPDRLRQTIPILLDALWNHSFDKKIVAQEKAVITSEIQTAHLNHQLSYHYQLISMLS
                     PSSPAAVFPAGRIEDIEALDISDLQKAYKAAYQTHRMTLFLIGGSENTETLLPPHLQLE
                     KRPDYHTERKIIPACPPALSQKMMLGDEERMEDTWTGLQIGALPGQNDLLTIKLYWDIA
                     ARILFQLDSPFFQEIQQTYRLEIDRLSAETYIYEDGGFLILHSQGTHSSAYIDVASYYV
                     TQKKEQAAAWLQYGKDSLTDAIIYDSDYVRKCFEWAAECDRCDCSFLDMYHIIQDMDAQ
                     VFLSLIDAMASSNKAIIYISQKEAIRQ"
     gene            16237..16938
                     /gene="albG"
                     /locus_tag="D9C11_RS09205"
                     /old_locus_tag="D9C11_09205"
     CDS             16237..16938
                     /codon_start=1
                     /gene="albG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391623.1"
                     /locus_tag="D9C11_RS09205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09205"
                     /product="antilisterial bacteriocin subtilosin biosynthesis
                     protein AlbG"
                     /protein_id="WP_088272551.1"
                     /transl_table=11
                     /translation="MKKNTVFTLLLLLIGMAAYSFGWVQAVAEAAAHYIQMINNDAVRL
                     GLLACTAALLMLPAFLYLHYVTQSVKNMTAAFQKLTQSHQSCCDFQQHNLCSRYAEDVK
                     SLRDGYKNVRQTYVMAAVLCQVIIFGCMFEIVKAVPFRLHTPPALSMGLAMLLILYLLF
                     CMRTYLRQLFRHGSLFRKVFAGALAAAGIWWMLSFTISELLFLIILAAIQQIGSFIYKR
                     FSYRSTASLDL"
     gene            complement(16944..18311)
                     /gene="ywhL"
                     /locus_tag="D9C11_RS09210"
                     /old_locus_tag="D9C11_09210"
     CDS             complement(16944..18311)
                     /codon_start=1
                     /gene="ywhL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017696256.1"
                     /locus_tag="D9C11_RS09210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09210"
                     /product="YncE family protein"
                     /protein_id="WP_121591253.1"
                     /transl_table=11
                     /translation="MDLSALQENCFCFCDEEISREAPFQVPIDIPEGFKVDSAEASAAV
                     TWSTDNVSCISEPCLIQTGPEPEDIGVRYAVRVQGTITLLVSVSPVRNQYGQGNGAVSV
                     IHTEEIDQVVYYAAQSGRCPDFSQITVEDLLIVPPFYGSPLTVAGTLVLPPSPDPQSYV
                     FTANTGDSTVSVIDADLNTVVKTIPFSDVPTNLGVTFDKAFTYVLHGNTNLVSVIDNKT
                     LTIINTITVGGGPRKIEFDPKDEFAYVMAAGSIYVINTASQSVIDVIPIPGALDFALDP
                     NGQYVYTANGSSWSVDKYDINTGQLVESIIDTFEFPSLIATPYAGNFAYVLNGELWPKG
                     VTEISLSPLSRGGDFSRLFETLRTIVFSLDSTRAYFLEPYSEPFLINNLYVVNTARQRI
                     IANVSLPGAFDLAVTPDKQYIYAAQPNDNAVTVYRTSDYTAVKVIPVGAGPSAIVM"
     misc_feature    18287..18304
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     gene            complement(18360..19715)
                     /gene="ywhK"
                     /locus_tag="D9C11_RS09215"
                     /old_locus_tag="D9C11_09215"
     CDS             complement(18360..19715)
                     /codon_start=1
                     /gene="ywhK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391625.1"
                     /locus_tag="D9C11_RS09215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09215"
                     /product="YncE family protein"
                     /protein_id="WP_121591254.1"
                     /transl_table=11
                     /translation="MRKNKLSFKEKAGAEQEECLYFCEGEASREAMFQAPIELSEGFVV
                     DPAEAVANVTWNADSLSCVSDRCLIQTGPEPDEVGVQFAVRLQGTVTLLVSVSPVRNQY
                     GQGDGAVSVIHNAEIDQVVYYSDEPDDCPDISDITIENLVVVPPFYGSPLSVTGTIVLV
                     PEPEPVYAFTANPNDQSVSVIDTNTHTVVTTIALPYNPAGIEITPDKSAVFVLHPNNNV
                     ISVIDYDTLTVTATILLDQPPRLIRFIPNHEFAYVFTGTAIYVIGIDTLTVERSIPVEG
                     FDIAIDPNGLFAYVLNFGLVQKVDLSTGEVTGTIERELIVSSIETDSTERYAYVLEQEF
                     LFNYLTVIDLNTFTIRDTQELEPDGLYVMFTSGSEVYLYDDFTGNLYSVSPNGAGVIGN
                     LPQSATDYAFTPNGDFLYATRFIEQSIIVYNTDDYSEETVISLGVSPGAITI"
     gene            complement(19712..19942)
                     /locus_tag="D9C11_RS24390"
                     /old_locus_tag="D9C11_09220"
     CDS             complement(19712..19942)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009968328.1"
                     /locus_tag="D9C11_RS24390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09220"
                     /product="hypothetical protein"
                     /protein_id="WP_041334639.1"
                     /transl_table=11
                     /translation="MQIPPFIILYMSYFIINILVRSAKKPQFFLSLHRMFGDIFSKRSV
                     YPQQFVQANTLLFHILLYLREQCMSEKEVKE"
     misc_feature    19896..19912
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 22.81"
                     /tool="antismash"
     gene            19945..21090
                     /locus_tag="D9C11_RS09225"
                     /old_locus_tag="D9C11_09225"
     CDS             19945..21090
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_391626.1"
                     /locus_tag="D9C11_RS09225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09225"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_017696253.1"
                     /transl_table=11
                     /translation="MTGVISSSSIGEKINEWYMYIRRFSIPDAEYLRREIKQELDQMEE
                     DQDLHLYYSLMEFRHNLMLEYLEPLEKMRIEEQPRLSDLLLEIDKKQARLTGLLEYYFN
                     FFRGMYELDRREYVLAIQFFKKAESKLVFVKDKIDKAEFFFKMSEVYYYMKQTYVSMDY
                     ARQAFEIYSEQTTYDIRMIQCQSLFGANFLDLKQYEKAIAHFQKAFTLAKTEQQPQLMG
                     RTLYNIALCKQNQNSFESAIEYVKKSIQVFEGSKMLPSLPQAFFLITQIYFKLGKIDNA
                     CEYHKKGKEYSAAAGDTVYLTEFEFLESLYLSGPDEERIEKCFVFLESKMMYADIEDFA
                     LDVAKYYHQQENYKKASHYFLKVEEARQHIQGGVNLYEMEV"
     gene            21074..21193
                     /locus_tag="D9C11_RS09230"
                     /old_locus_tag="D9C11_09230"
     CDS             21074..21193
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003326489.1"
                     /locus_tag="D9C11_RS09230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D9C11_09230"
                     /product="PhrC/PhrF family phosphatase-inhibitory
                     pheromone"
                     /protein_id="WP_014665774.1"
                     /transl_table=11
                     /translation="MKWKYKLLLACLAVSAVFITVEVSNSSTEHFDVAQRAMI"
ORIGIN
        1 caagagtgat ccgactgaga gatgttttcc gttaatccgc gagcattctg gagatgacca
       61 gtctttgaat ttcttgagtt ccttcataga tttgcgtgat ttttgcatca cgcatatagc
      121 gttctaccgg ataatctttt gtatagccgt agccgccgaa aatctgcacg gcttcagtcg
      181 ttaccttcat cgccgtatcc ccagccatca gtttggacat agcggaagct tttccatatg
      241 gaaggcccga tgattctaac cacgcagcct gataggtcaa tagccttaag gcttctatca
      301 ttgtcgccat atccgcgagt ttaaaagcga tgccctgctg ctcgccgatc gattttccga
      361 attgctttcg ctcttttgca tattgaagcg ccgcatcaag cgctccttgg gcgatgccta
      421 cggcttgtgc agctatgccg tttctgcctc cgtcaagcgt cttcatcgcg attttgaagc
      481 cttctccttc ttgtccaaga cgctttgatg cgggcactac acaatcttcg aacatgattt
      541 ccgttgtcgg tgaagaacgg atgcccagct tcttttcttt cttgcctgta aaaaatcctt
      601 caaaatcctt ttctactata aaagcggtaa tgcctttttt ctttttctcg ggatcggtga
      661 cggcaaaaac aatgtaaata tcagcaacgc cgccgtttgt gataaacact ttggaaccat
      721 ttaacacata gtcatcgccg attcgttcag cagttgtttt catgctgccg gcgtcagatc
      781 cagaccgtgc ttcggtcaat gcgaatgcgc cgattttctc tccgagggcc agttgtgtta
      841 agtactctgt cttctgttcc tccgtcccaa aggcaaacag gggccagctg caaagagaga
      901 tatgggcgga aagcgtcact ccggtggagg cgcacacttt tgacagctcc tccaccgcga
      961 tgacgtaggc caaatagtca cttccgattc cgccgtaatc ttcaggccat ggaattcccg
     1021 tcagccccag atttgccatt tcccgaaaca gctcgcgatc gaagcgttct tgttcgtccc
     1081 gttctgccgc agtcggggcc acctcatgct tcgcaaaatc gcgcaccaat tttcgtatca
     1141 tctggtgttc ttctgataat gaaaaattca ttgcttctcc cccattttca gatcagcgcc
     1201 taaaacggat tgagccagaa gctcgacgac gtcgtacgtt ttgacttggt cttcagcttc
     1261 catcgccttt gtgccgtccc caagcattgt gagacagtac ggacagccgg aactgatcac
     1321 cgatgggttg actgcgagcg cttgctctgt cctggcgaca ttaatcctgt tgcctgtttc
     1381 ttcctccatc cacattaatc ccccgccagc tccgcagcac atgccggttt cccggtttct
     1441 ctccatttca acaagctgca cgcccggaat gcctttcaaa atctctctcg gcggatcata
     1501 gacttcattg taccggccca aatagcatga atcatggaag gtaatcgtct catgaagcgg
     1561 gtgctgcggc tttaattttc cgtttttcac aagctcggcc agcacttctg tatgatgata
     1621 aacctcgcct tcaaatccga aatccggata ttcgttttta aataaattgt atgcatgggg
     1681 atcgatcgta acgatttttt tgacatcatt tttttcaaat tcagaaatat tcttctcagc
     1741 cagctcttgg aacaaaaatt catttccgag gcggcgcggc gtgtctcctg aatttttttc
     1801 tttattgccg aggatcgcga aggacacgcc cgcgtgattg agcagcttgg caaaggaaat
     1861 tgcgattttc tggcttctgt tgtcgtaaga ccccatggag cctacccaga aaaggtactc
     1921 aaattctttt ccttcttttt tcatttcttt tacagtcgga atctcagcat ccggcgcctc
     1981 atcacgccaa ttttcacgtt ccttgcggtt gagtccccac ggattcccct gccgctcaat
     2041 acttgtcatt gcgcgctggg cgtcactgtc catttttcct tctgtcagta cgaggtagcg
     2101 gcggaggtcg atgattttat ccacgtgctc attcatgacc gggcattgat cctcacagtt
     2161 tcggcaagtg gtgcatgccc aaatttcttc ctctgtgatg acgtcgccga tcaagcttgg
     2221 attgtaatca agcgccgctg cggcttcctg cgatccgctg cccgctgacg ccgcagccag
     2281 ctgattgcct ctcgtatgcc gaaacgctgc tgcgggcacc catggggagc gcgaggtgac
     2341 ggcagcgcct ttttccgtga gatggtctct gagacgtaaa atcaagtcca tcggagacag
     2401 catttttccg gtgcctgttg cagggcacat attggtacag cggccgcact cgacacacgc
     2461 gtacagatca agcagctgag actgcctgaa atcctcaatt tttcccgctc cgtagctttc
     2521 tttcgtttcg tcggtaaaat caattttttc aagttttccg gcagattcca ttctattgaa
     2581 aaagacgttt gccgggccgg cgattaaatg ggcatgctta gactgaggca cgtacactaa
     2641 aaagctaagc aagaacagaa gatggatcca ccatgcgata tagaaaatca ccgccgcacc
     2701 tgttttcccg actccgctaa gcataaacgc aatacctgag gcaattggct cgctccaaga
     2761 aagcccatgc tcatgccaaa tcagattcat cccgttccca agcagaacgg tcagcattaa
     2821 acctccgata aaaatgagaa cgagtccggc tttgaaaccg cgtttcagcc tcacgagctt
     2881 ttcgatgtaa cgtctgtaga atgcccaccc aacagcaatt aaaatgagaa acgtaacaat
     2941 ttcctgaaaa aaggtgaagg cgggatagac cgggccaagc ggcagattcc ggccgggagc
     3001 cagtccttta atgataaagt caattgctcc gaactgaacc aatataaatc cgtagaaaaa
     3061 catgacgtga atgattccgc ttttcttgtc cttgagcagt tttttctgtc cgaatacatt
     3121 cacccatatg tcgtgaagcc gttccttgaa ccgttgatca aattgttctt tctggccgag
     3181 cttgatgtag gccagtctcg ttttgaccaa atacacaaac aaatagacag cgtaagcggt
     3241 tacaatcaga aataataatg tatttgcgat gagaaagccg ctcattccaa ttcccccttt
     3301 ttactgataa agaccgcgat cctctacccc cgaatctgta taagattatc tttatgataa
     3361 ataatgaatg agtgttcagt caataattaa attcctgctg ttcgggcaca ctacctttac
     3421 tacggaaagg agtgccggta tgaaagtatt tatcgtgatt atgatcattg tcgttatttt
     3481 ctttgccttg attctgcttg atatcttcat gggccgtgcc ggatacagaa aaaaggcgta
     3541 cgagcctgtt ttttcaaaaa agaagagtga catcgaattg atccactgcg gcgctgatct
     3601 cgttgagcgg atgatgaagg atattcgcca ggccgcctct tctgttcaca tgatgttttt
     3661 tattatgaaa aatgatgagg tcagccacaa tatgtatacc ttgctgaaag caaaagcaca
     3721 agccggtgtt tctgtttatt tgctgctgga ttggtccggc agccaaaaaa ttaaaaagcc
     3781 ggcgctgcag acgatgaaaa atgccggggt tcaggttcat tttcttaaca agcctcgttt
     3841 tccttttttc ttttttcata tgcaaaaacg gaatcaccgg aagattacgg tgatagacgg
     3901 aaaaatcggt tatatcggcg ggtttaacat cgccgaagaa tatcttggaa agaaagcgaa
     3961 gttcggcaat tgggaggatt atcatttgcg tatgaaggga gaaggcgtac atgatcttca
     4021 aacggttttt gcttctgatc taaaacgaaa taccggaatc gaacttggtt cggaagtttg
     4081 gccaaagctt cagcaaggga ctatttctca caaaatatat gcgactgacg gttattccct
     4141 tgaaaacaaa tacttggcca acattgccca agcgaagaat cgccttacgg tttgcacgcc
     4201 ttattacatt ccatcaaagc cgcttcaaga ggcccttatt aacgcaagaa aaaacggcgt
     4261 atccgtgaga atcattgtac cgatgaaatc agaccatccg ctggtacgag aagcagcttt
     4321 tacgtattat tcggagctct tggatgccgg ctgtcttatt tatcgttatt atcaaggatt
     4381 ttatcatgta aaagccctca tcatagacga ccatctcagc ataatcggat cagccaactt
     4441 cgataaacgg agcctgtttt taaatgaaga ggtgaatgtc gaaattgatg acgaagcgtt
     4501 tacaagtgaa gtctatgcca cgattgagga ggatatgaaa aagtcggagc ggctgaccat
     4561 ggaggatttc agcaagcgca cattcaggca gcgcccggcg gaatggctcg gcagggcatt
     4621 atcttatttc ttataaagga gagttcctat gattttcaga ttcgggttcg tttcaaatgc
     4681 gatgagcctt tgggatgcgt ctcccgctaa aacattgaca ttcgcgcgtt attcaaagct
     4741 ttcaaagact gaaagaaaag aagcgcttct gactgtgaca aaagccaatt tgcgtaatac
     4801 gatgagaacc cttcactata tcatcggcca cggcattcct ttgtaccgtt tttccagttc
     4861 gattgtgccg ctggctacgc atcccgacgt gatgtgggat tttgtaacac cgtttcaaaa
     4921 agagtttcgg gagattggag agcttgttaa aacacatcaa ctgcgaacaa gctttcatcc
     4981 aaatcaattc actctgttta cgagcccgaa ggaatccctc acaaaaaatg cgataaccga
     5041 tatggcgtat cactaccgca tgcttgaggc catgggcatt gctgatcgct ccgttatcaa
     5101 cattcatatt ggcggcgctt acggaaataa agacaccgcc actgcacaat ttcatcaaaa
     5161 tataaaacag ctgccgcagg agatcaaaga tcggatgaca cttgaaaatg atgataaaac
     5221 atatacaacg gaagaaacgc ttcaggtctg tgagcaggag gatgttccgt ttgtctttga
     5281 ctttcatcat ttttacgcca atccagacga tcacgtcgac ctgaatgtag cactgccccg
     5341 catgatcaaa acgtgggagc ggatcggcct tcagccaaag gttcacttgt cttccccaaa
     5401 atcggagcaa gcgatacgca gccatgccga ttatgttgac gccaactttt tgctgccgct
     5461 gttggaacgc tttaggcaat ggggaacgaa tattgatttc atgattgaag caaagcagaa
     5521 agacaaggcg cttctccgct tgatggatga attaagctcc atccgcggtg tcaaacgcat
     5581 cgggggcggt gcgctgcaat ggaagtcata aatgtgcaaa aataggttta cgacttgtca
     5641 gctttgggaa cttaggctat ataagacaac aatcgatgga ggagaaagat catgaaaaat
     5701 atcaagtctc tgaaagtagc cgcacaggcc tttactttaa gaaatttgat tcatctttat
     5761 aaaatgtgcc attccggaag ccacgaggtt tatatttatt caaagaaaac gatgtgcaaa
     5821 atcaaaagct taattgagct tgaaacattc cgcatggctc ataatgaaaa ggaatatctg
     5881 atcgtagttg aaggaacaaa agcatcacag ctcattgaaa aattccaaaa tctcatcgag
     5941 cctgctgaga gagaagcgct ctaacttaca tacaaaaaag gatagacatc tgtctatcct
     6001 caggctgtcg agaaaatctc gacagccttt atttttcctt aaaatatcca ttcttctgta
     6061 ataaaataaa agaaagactt aaaaggacgg tgtctttctc atgttccaca caagaaactc
     6121 ttctcaaaac acagccgaat ttgttctgct tgaccaactc gttgaagagg atcacctgct
     6181 tcggaaaatt gataaacaca tagacttctc tttcatcatt gaaaaggtga aaccttacta
     6241 cagtgaaaac aaaggccgcc cctcacttga tccgcttatt ttatttaaaa tgatgtttat
     6301 cggatacctc tatggtatcc gttcagaaag acagcttgaa aaagaaattt actacaatat
     6361 ggcgtacaga tggtttctcg gattgaacat aaacgacccg gttccacacc actccaccat
     6421 cagctggaac agacgcacac gctttaaaga tacaaccatc ttccaagaca tttttgatga
     6481 gatcgttctt caggccatca atcatgacat ggtgggcgga cgagtcctat tcaccgactc
     6541 cacacacctt aaagccaatg ccaacaagca taaatacaca agaaaaacaa ttgcgcagga
     6601 tacccaaaac tatatcaagg atttaaatga agccattcaa gaggatcggg aggaacacgg
     6661 aaaaaagcca ttaacagcca aagaggaggt gaaagctgaa aaagagatcc gccacagtac
     6721 aaccgatccg gaaagtggct atctgtatcg tgaaaacaaa ccagaaggtt ttttctattt
     6781 agatcaccgc acaacagata tgaaatacaa cattatcacc gatgcctacg tcacacctgg
     6841 aaatgtccat gattctgtgc cttatcttga ccgattagac caccaaatcg cacgatttgg
     6901 ttttcaagta gaagccgtcg cccttgattc cggatattta acgactccga tctgtaaagg
     6961 attatctgac cgccaaatct ttggtgtcat cgcacataga cgttatcacc ctatccgagg
     7021 cttgtttcca aaatggaaat ttcattatga cagtgaacaa gacagataca tttgtccaaa
     7081 tcaccaaaca cttacatact caacaactga ccgaaaaggc taccggtcat acaaatcaaa
     7141 tcctgaaata tgttcctcat gcccgctgct tgaaaactgt acaaaatcaa agaatcggca
     7201 gaaagtgatt actcgacatg tatgggaaga tcataaagaa aaggtcagac aaaatcgctt
     7261 gtctgtttca ggaaaaaacc tctacaaaaa aagaaaagaa aaaatagagc gaagctttgc
     7321 agattcaaaa caactgcatg ggcttcgcta ttgcaggttg aggggaaaac gaaatgtgag
     7381 tgaacaagtt ctcctcacag ccgcatgcca gaacatgaag ttgccacata cctagccaag
     7441 caaggctagg catgtgggag cgctttttct gaatctgaaa cctggtgaat atctaaagaa
     7501 acagtataaa acaaaaaagc ttgtagaaaa aacatcgttt tctctacaag ctaaggacaa
     7561 agcccgaaga ctttgtcctt ttgatcgtga ttacattttt tccggagccg atacgccgat
     7621 cagctgaagc gcattgttca gcgtaatttg cgttgccttc attaaagcca ggcgcgcgcg
     7681 gcttttctct tcattttcag ggtcgatgac tttctctgcg ttgtagaagc tgtgcagagc
     7741 agaggccaga tcataaatat agtttgtgac acggtgcgga attcgttttt ccgctgcttc
     7801 cgccactgcc tctgggaagc cgccgatcgt tttcagcaga tcgtattctt tttctgattg
     7861 aatatggctg aaatcaagat ccgccgccgg tttaagcccc tgctcttccc cttggcgaag
     7921 catgctgcaa atacgtgcat gcgcgtattg tgcataatac acagggtttt cgttagatgt
     7981 tgatacagca agatctaagt caaaatccat atgggtgtcc gcacttcgca tcgcaaagaa
     8041 gtaacgaacg gcatccaagc cgacttcttc aatcaggtca cgcatcgtta cggctttacc
     8101 ggtccgtttg ctcattttca ttttctcgcc gtttttgtaa aggtgaacga gctgaatgat
     8161 ttctacttca agcgttcctt tttcatagcc cagcgcttcg attgccgctt tcatacgcgg
     8221 gatgtagccg tggtgatcgg cgccccaaac gttgatcagc ttatcaaagc cgcggtcaag
     8281 cttgtcctta tgatacgcga tatcaggaag caggtacgtg tacgtgccgt ccttcttgat
     8341 caatacgcgg tctttatcat cgccaaacgt cgtggaacgg aaccaagtcg cgccgtcttc
     8401 ttcatagaca tggccttttt cgcggagcgc ttcaagcgcc ttgtcgattt ttccattttg
     8461 gtacagtgaa gtttctgaat accacacatc aaacggcaca cggaagtttt ccaagtcctt
     8521 gcgaagcttt tccagctcgt atttcaggcc gtattcacgg aaaaacgcga ggcgttcact
     8581 ttcttcttcg ttaacgaaac gatcaccgta ttcctcagcg agacgctttc cgatcgcaat
     8641 gatatcctcg ccgcggtagc catcctccgg catcggtttt tccaatccga gtgcttcaaa
     8701 gtaacggact tcaacagaaa gcgccagatt gttgatttgg ttacccgcat cgttaatgta
     8761 gtattcgcgg cttacatcgt aacccgcttt tgaaagcacg ttgcacaagg aatcgccgac
     8821 agccgccccg cgcgcatgcc cgaggtgaag gtctcccgtc ggattcgctg acacgaattc
     8881 tacctgaacc cgttcaccgt ttccgatgtt cgtttccccg tatgcttccc ctgcttccag
     8941 tacagacgga atcagctttg ttaaatattg attgttcata tagaaattga taaaacccgg
     9001 gccggcgata tccagttttt caatcgaagc ctttccttta tcaaaatggg cgacaatctc
     9061 ttcagcgatt tggcgcggcg ctttttttgc cactcttgcc agctgcatcg ccatattcgt
     9121 tgagtagtcg ccgtgtgttt tatctttcgg tgtttctaaa acaacattgg gaatctggct
     9181 ttcttcagcc agtcccgctt tcagaacggc cgctttgatt tcttctttca gcacgtcctt
     9241 catttgttcc gcaatgttca tgcgtgagtt cctccctcat acgtgatcgt catattatgt
     9301 aaatgctcct gctcgtctcc gacatgcatg tcatatgcga tgctgatacg gcctttttct
     9361 tcatcgagat cagattgaat cgattttgtg cttgttttca gctcaagctc accaaatgac
     9421 attttatatt tagcaattgt ggaagctccc tttacgaatc gctgattcat tttgacagcg
     9481 cctgacctca tgaccaggac ttcgccttcg cttactttca caatcgtttt gactttgcct
     9541 aagtcgtgtt cttcataata agatagatac actttatttt gttttacata gtaaaatccg
     9601 gtggtgcgga attcgatgac ttcttggttt ccgtcatcct cgatcacaga cttcacatgg
     9661 agtgttatcg gtgtctcttg cttcattctg acacgtcctt ttcatcattc cactttgact
     9721 tgaatagtat aatcattcgg tttgtaaact tcaactgctt ctatcttacc atcattgctc
     9781 atcagatttg aagataaacc tcataaaaag catttcctta tatagaagag aaaatcatat
     9841 cactaattac ctttagtaaa tgttacattt ttccgaaatc tatcatttcc ttttcacatt
     9901 tttttcaaaa tatatgtatt gaattagtaa tttgatagtt ttaagataaa agtacaacat
     9961 agatctgtta gaaaaacaaa aaaaaaggga ggattcaatt atgaaaaaag ctgtcattgt
    10021 agaaaacaaa ggttgtgcaa catgctcgat cggagccgct tgtctagtgg acggtcctat
    10081 ccctgatttt gaaattgccg gtgcaacagg tctattcggt ctatgggggt aaggatctcc
    10141 caaaagggca tagtcattct actatgccct ttttaagtaa attacaattt ttaactaaaa
    10201 tctacctctt ggatatacat acacaaccgt ttttcatttg aatcatatgt ataggggatg
    10261 gtattttgtt tatagagcag atgtttccat ttattaatga aagtgtaaga gttcaccagc
    10321 ttcctgaggg cggcgtgtta gaaatcgact acttgcgcga taatgtctcc atttctgact
    10381 ttgagtattt ggatctcaac aaaacagctt acgagctctg catgcgcatg gatggccaaa
    10441 aaacagctga gcagatttta gctgagcaat gtgcagtgta tgatgaatca ccggaagacc
    10501 ataaagattg gtattacgac atgctcaaca tgctccagaa caagcaggtt atccagcttg
    10561 gaaaccgggc catccgccat accatcacca cgagcggaag caatgaattt ccgatgcccc
    10621 tgcacgccac ctttgaactg acgcaccgct gtaatttgaa atgcgcccac tgttatttgg
    10681 aaagctcgcc tgaagcgctc ggcaccgtgt cgattgagca attcaaaaaa acggctgata
    10741 tgctgtttaa taacggtgta ttgacatgcg aaatcacagg cggagaaatt tttgtccatc
    10801 caaacgccaa tgagattctt gactatgtgt gtaaaaagtt caaaaaagtc gctgtcttaa
    10861 caaacggaac actcatgcga aaagagagcc tggagctttt gaagacttac aagcaaaaaa
    10921 tcatcgtcgg catttctctt gatagtgtca attccgaggt ccatgactcc tttagaggga
    10981 gaaaaggctc ttttgcccaa acttgtaaaa cgataaaatt gttgagtgac cacggtatat
    11041 ttgtcagagt cgccatgtct gtcttcgaaa aaaacatgtg ggaaatccac gatatggccc
    11101 aaaaggttcg ggatctcgga gcgaaggcgt tttcttacaa ttgggttgac gatttcggaa
    11161 gaggcaggga tattatccat ccaacgaaag acgccgagca gcaccgcaag tttatggaat
    11221 acgagcaaaa tgtgattgat gagtttaaag atctgattcc gattattccc tatgagagaa
    11281 aacgcgcggc aaattgcggc gctggctgga agtccattgt gatcagcccg ttcggcgaag
    11341 tacgtccttg cgccctcttt ccaaaggaat tttcattggg aaatattttt catgattcct
    11401 atgaaagcat ctttaactcc cctctcgtcc ataaactgtg gcaagcgcag gcgccgcggt
    11461 tcagcgaaca ttgcatgaaa gacaaatgcc cgttcagcgg ctattgcgga ggctgttact
    11521 taaaagggct gaactctaac aaatatcacc gaaaaaacat ttgctcttgg gcgaaaaatg
    11581 aacaattaga agacgtggtc cagcttattt aggagggaaa cgatttgtca ccagcacaaa
    11641 gaagaatttt actgtatatc ctttcattta tctttgtcat cggcgcagtc gtctattttg
    11701 tcaaaagcga ttatctgttt acgctgattt tcattgccat tgccattctg ttcggaatgc
    11761 gcgcgcggaa ggctgactcg cgatgagcat tttggatata cacgatgtat ccgtttggta
    11821 tgaacgggac aacgtcatct tagaacaagt ggatttacat ttagaaaaag gcgccgttta
    11881 cgggctgctt ggggtaaacg gcgccggaaa aacgacactg attaatacgc tgacaggcgt
    11941 gaaccgcaat ttcagcgggc gctttacact gtgcggaatt gaagcggagg ccggcatgcc
    12001 gcagaaaaca tcagatcagc tgaagactca ccgttacttc gccgccgatt atccgctgct
    12061 atttacagaa attacggcga aggactatgt gtctttcgtc cattcgcttt atcaaaagga
    12121 tttttcagag cagcagtttg ccagtttggc cgaggccttt catttttcga aatacatcaa
    12181 caggagaatt tcggagctgt ccttggggaa caggcaaaag gttgtattga tgacaggctt
    12241 attgctgcgc gctcccctat ttattttgga tgagccgctc gtcggtttgg atgtggaatc
    12301 gatagaggtt ttttatcaga aaacgcgcga gtactgtgaa gcaggcggga ccattttgtt
    12361 ttcttctcat ctgctcgatg tcgtgcaaag attttgtgat tacgcggcca ttcttcacaa
    12421 caaacagatc caaaaggtca ttccgattgg agaggagacc gatctgcggc gggaattttt
    12481 cgaggtgatc ggccatgaat aacataatcc ccatcatgtc tttgctgttc aaacagcttt
    12541 acagccggca agggaaaaag gacgccatcc gcattgccgc aggccttgtc attctggccg
    12601 tatttgaaat cgggctgatc cgccaggccg gcattgatga atcggtgttg cgcaaaacgt
    12661 atatcatact cgcgcttctc ttaatgaacg catatatgct gtttctttct gtgacatctc
    12721 aatggaagga atcttatatg aaactgagct gcctgctgcc gatttcttca cggagctttt
    12781 ggctcgccca gagtgtcgtt ttgtttgtcg atacctgttt gagaagaacg ttattctttt
    12841 ttattttacc gctgttctta tttggaaacg gaacgctgtc aggggcgcaa acattgtttt
    12901 ggctcggcag gttttcgttt tttaccgttt actccattat tttcggagtt gtgctaagca
    12961 accacttcgt caaaaagaag aacttgatgt ttctgctgca tgcggcgata ttcgcctgtg
    13021 tatgtctcag cgccgctttg atgccggccg ccacgcttcc gctttgcgcg gtgcatatgc
    13081 tgtgggcggt ggtcattgac tttcctgtct ttctgcaggc gcctccgcag cagagcagga
    13141 tgcattcatt tatgcggcga tctgagtttt cgttttacaa aagagaatgg aaccgattta
    13201 tctcttctaa agcgatgctg ttaaattacg cggtaatggc ggcgttcagc ggcttctttt
    13261 cgttccagat gatgaatacc ggcatcttca atcagcaagt gatttatatc gtgatttccg
    13321 cgcttctgct catctgctcg ccgatcgccc ttttgtactc gattgaaaaa aatgaccgca
    13381 tgctgctcat cacgcttccg atcaagcgga aaacgatgtt ttgggcgaaa tatcgctttt
    13441 attcaggcct attggcaggc ggatttctcc ttgtcgtgat gattgtgggt ttcatcagcg
    13501 gccgtccgat ttcagttctc acttttttgc agtgcattga gttgctgctg gcgggagctt
    13561 ttatcaggtt aactgcggat aaaaaaaggc ccttcttcag ctggcagacg gagcagcagc
    13621 tatggagcgg tttctcaaaa tatcggtctt atctgttttg tcttccccta ttcttagcca
    13681 cattaaccgg caccgctgta tccttggcgg tcattccgat agccggtctg gtcatagtct
    13741 attacctgca aaaacaggat ggtggtttct ttgatacaag caaaagagaa cggcttggaa
    13801 gttaacctgc tgaagactca tcaattttca actatatcaa tcgccgcgag ctttctgaaa
    13861 ccgatcgaaa gcgcggcgga acctgaggaa gaaacgattt atttttacgg cgccgccgca
    13921 tacctgaagg agcaaatcat tgacgatttc ggttgtgctg ccggcagccg tttcatgtac
    13981 tcagcgaatc tcttttttga tcagcagctg aaaacctgcg ggacccgttt gattcaccca
    14041 ttatataacg ggaatcttca tgttgacgcc ctgatgaaaa cttttgcaga cttgtctttc
    14101 ccttcttctc tttcattcga agcagttgaa aaggccagga atgagctgct gctgaaaatc
    14161 gaaaagaaat tcactgatcc cttctcctac tcggcggcgc gcttggctga ggaggtcttc
    14221 ggaaacccga tgtacggcac aggcatgttt ggccggaaag acaggataaa ggcgattcat
    14281 cctaaacggt ttcacgacgc aacggacttt atcgttgatt tagcgtccca gcaaaaacag
    14341 ctgaacatat tgggacaagt acaagcatgt gatgttcggg gacatgcccc gcaaacgtcc
    14401 gctgtaacgt ccgaaagaat acccgtaaac cggcatgttt ttgaaacaga gacacgcagc
    14461 gctgcaggtc cttccgtctt gacactcgga tttgactgcg gagagatgaa agatgccagc
    14521 gattatatca aaatacagct aatagacgga ttactgggaa agtacggcca ttccgcttta
    14581 ttcaagcact tcagagagaa agatctggca gtctatcacg ttatcatccg ttacgatgtc
    14641 atgaacaatt tgctgcttgt ttcaatatgt acagatcagc ttcatgagat agacattccc
    14701 ccgcgcgttt tggaagctgt ctcagctttt catacagatg agcgggaact agaacaggca
    14761 aagcagtttt tacgcaatga attgctgctg caattcgatt ctcccgaagg tctattggcc
    14821 tatatgggga tcctgcgccg cttctcctgc acgaaagaag ccttgctgga tggcatctca
    14881 gcggttacat gccgtgatgt attgcaattc atagcgacca tcaattatat cggagctcat
    14941 gtagtaaggg gatgaaaaga tggaaaagaa agcctttttt caacagctgg atgaacgaac
    15001 cgatatcaga tacacagaca gcggactaaa aatattcaga ttgaaattcc cccgcgccca
    15061 cctgcggctg tgcaatgtaa aaatcgattt tggaagccgg gatgtatgta tacgggcaga
    15121 atccggtgat acactgcttc cgtatggcac agcgcatttt ttagagcatc ttctcttctg
    15181 gcataacggc cgcaatctgt acagtgattt ttttgcgcat ggcgcgcttt taaacgcatt
    15241 cactacctac accgatacca atttcatgtt tacctcatta ccggatcggc tcagacaaac
    15301 gatccccatc ctgcttgatg ctttatggaa ccactcattt gacaagaaga ttgtcgctca
    15361 ggaaaaagct gtgattacaa gcgaaattca aacagcacac cttaaccatc agctctcata
    15421 tcattatcag ctgatcagca tgctttctcc ctcctcacca gctgccgttt tccccgcagg
    15481 cagaatcgaa gatattgagg cgcttgacat cagtgattta caaaaagcct ataaggctgc
    15541 ctaccaaacc catcggatga cgctgttttt gattgggggc tcagaaaata cagaaacgct
    15601 tttgcctcct cacctccagc tggaaaagcg tccagattat catactgaaa gaaaaatcat
    15661 cccggcatgc cctccagccc tctcacaaaa aatgatgctg ggtgatgagg agcggatgga
    15721 agatacatgg accggattac agatcggcgc acttcccggg caaaacgatc tgttgacgat
    15781 caaactttat tgggatatcg cggctcgtat tctatttcaa ttagattcac cgttttttca
    15841 agagattcag caaacgtacc gcctggaaat cgatcgtttg tcagccgaga cttatatcta
    15901 tgaggatggc ggtttcttga tccttcacag tcaagggacc cattcttcag cttatatcga
    15961 tgtggcttca tactatgtca cacagaagaa agaacaggct gccgcctggc ttcaatacgg
    16021 caaggactct ttgacagacg cgatcattta tgacagcgat tatgtgcgta aatgcttcga
    16081 gtgggcagcc gagtgtgaca ggtgcgattg ctcgtttctt gacatgtacc acatcattca
    16141 agatatggat gcgcaggttt tcttgtctct cattgatgca atggcatctt ctaacaaagc
    16201 gatcatttac atttctcaga aagaggcgat cagacaatga aaaaaaacac tgtctttacc
    16261 cttttattgc tgcttatagg tatggcggct tattccttcg gctgggttca ggccgttgcc
    16321 gaagccgccg cccactatat acagatgatc aacaatgatg ctgtacggct cggactgctg
    16381 gcttgtaccg ctgccctcct gatgctgcct gcttttctct atcttcacta tgtcacccaa
    16441 tctgtgaaaa acatgacagc agcttttcag aaactcacac agtctcatca aagctgctgt
    16501 gactttcagc aacacaactt gtgcagccga tatgcagaag acgtcaaatc gctgcgtgac
    16561 ggctataaaa acgtccgcca aacatacgtg atggctgccg tgttgtgcca agtcatcata
    16621 ttcggctgca tgttcgaaat cgttaaagcc gtccctttcc gccttcacac gccccctgcc
    16681 ctttcaatgg gacttgcgat gctactgatc ctgtatttat tgttttgcat gcgaacgtat
    16741 ttgcggcagc ttttccggca cggcagcctg ttcagaaaag tgtttgcggg agcgctggca
    16801 gcagccggga tttggtggat gctcagtttc actataagtg aactgctgtt tctgattatc
    16861 ctggctgcca tccagcaaat cggatcattt atttataagc gattctctta tcgcagcacc
    16921 gcttctcttg atctataaaa tagctacatc acaatcgcag acgggcccgc gccaaccgga
    16981 atcaccttca cggctgtata atcacttgtg cggtacacgg tcacagcatt gtcgttgggc
    17041 tgtgccgcat aaatatactg tttgtccggc gttacggcga ggtcaaaagc gccggggaga
    17101 gacacgtttg caatgatcct ctgtctggcc gtattaacta catataagtt attaataaga
    17161 aacggttcac tatatggctc tagaaaataa gctctagtgc tatcgagaga aaatacaatc
    17221 gtcctcagcg tttcaaataa acggctgaag tcccctcccc tgcttaatgg agacaaacta
    17281 atctccgtta cacctttcgg ccacagctca ccattcaaca cgtacgcaaa atttccagcg
    17341 taaggagttg caattaaact gggaaattca aatgtatcta tgatactttc taccaactgc
    17401 ccagtattta tatcatattt atcaaccgac caactgcttc cattagcggt atagacatac
    17461 tgtccattcg gatcaagagc aaagtctaaa gcgccgggta tcggaatgac atcaatgacc
    17521 gattgagagg ccgtgttaat cacatatata gatccggcgg ccatcacgta tgcgaactca
    17581 tcttttggat caaattcgat ctttctcggc cctcctccaa cagtaatggt atttatgatg
    17641 gttaatgttt tattatcaat cactgagaca aggttggtat ttccatggag gacatacgtg
    17701 aatgctttat cgaaagtaac gcctagatta gttggcacgt cagaaaaagg gattgttttt
    17761 acaacagtgt ttaaatctgc atcaataacc gaaaccgtgc tgtctccagt attggcagta
    17821 aacacatacg attgagggtc tggtgatggc ggtaaaacaa gtgtcccggc caccgtaagc
    17881 ggactgccgt agaaaggcgg tacaatgagc agatcttcca ctgttatttg actgaaatca
    17941 ggacagcggc cagactgtgc tgcataataa acaacttgat caatctcttc ggtatgaatc
    18001 acagaaaccg ccccattgcc ttgtccatat tgatttcgca caggcgacac actgacaaga
    18061 agcgtaatgg tcccttgtac tctcacagca tatcgaacac cgatatcttc tggttccggc
    18121 ccagtctgga ttaagcaagg ctcactgata caggacacat tgtctgtact ccatgtaaca
    18181 gccgctgacg cttcggccga atcaaccttg aagccctcag ggatatctat cggcacttga
    18241 aacggcgctt ctcggctaat ttcctcatca caaaaacaga aacaattttc ctgtaaagca
    18301 gaaagatcca ttctttttca tgatttcacg tccttttaga aatgcacaac atgcagcggt
    18361 taaatcgtaa tggcacccgg tgaaacccca agagatatca cagtttcctc agaataatca
    18421 tctgtgttgt aaacaatgat gctctgctct ataaaacgag ttgcatacag aaaatcgcca
    18481 ttcggggtaa acgcatagtc tgttgctgat tgcggaagat ttccaattac acctgctcca
    18541 ttcggactga cagaatataa attgccggta aagtcgtcat ataaatacac ctctgatcca
    18601 ctcgtaaaca ttacatatag cccgtcaggc tccagctctt gggtatccct gatcgtaaac
    18661 gtatttaaat caataaccgt caaataattg aataagaatt cttgttctaa gacatacgca
    18721 taccgctccg tagaatctgt ttctatggat gatacgataa gctctcgttc aatcgttcct
    18781 gtgacttcac cggtagataa gtccactttt tgcactaacc caaaattaag aacataggcg
    18841 aacaacccat tggggtcaat tgcaatatca aaaccttcta caggaataga cctctcaaca
    18901 gtcaacgtat caattccaat cacataaatg gcagtaccgg tgaaaacata agcaaactca
    18961 tgattaggga taaatctaat caatcgaggc ggctgatcca gcaatatagt tgctgtcact
    19021 gttaatgtgt cataatcgat gacagaaatc acattattgt tgggatgtaa gacaaacaca
    19081 gcgcttttat ctggcgtaat ttcaatacct gccggattgt acggaagagc aatcgttgtc
    19141 acaacagtat gggtgtttgt atcaatcaca gaaactgatt gatcatttgg attcgctgta
    19201 aacgcgtaga cgggttccgg ctccggtaca agcacaatcg tccccgtcac cgataaagga
    19261 ctgccgtaaa acggcggaac aacaacaagg ttctcaatcg tgatgtcact gatatccggg
    19321 caatcatccg gttcatcgga ataatagacg acttgatcga tttctgcatt gtgaatgacg
    19381 gaaacagccc cgtccccttg tccatattga tttcgcacag gtgagacact gacgagtagc
    19441 gtaacggttc cctgcaggcg cactgcaaat tgaacaccga cctcatcagg ctctggcccc
    19501 gtttgaatta agcaacggtc actgacacaa gaaaggctgt ctgcattcca cgtcacgttt
    19561 gcaacagctt cagccggatc aacgacaaat ccttcagata attcaatcgg cgcttgaaac
    19621 atggcttctc ggcttgcttc tccctcacaa aaatataagc actcttcttg ttctgctcct
    19681 gctttttctt taaaggaaag cttgtttttt ctcattcctt cacttccttt tcagacatac
    19741 actgctcacg cagatataac agaatatgga agagtaacgt gtttgcttgt acaaattgct
    19801 gagggtaaac gcttcttttt gaaaatatat ctccaaacat gcggtgtaac gaaagaaaaa
    19861 attgcggttt ttttgcgctt ctcacaagaa tgttgatgat aaaatatgac atatatagaa
    19921 ttatgaaggg agggatttgc aaaagtgaca ggtgtcatat cttcttcttc catcggagaa
    19981 aagattaacg aatggtatat gtacatacgc cgatttagca tacccgatgc agaatatttg
    20041 cgacgagaaa tcaagcaaga gctggatcaa atggaagaag atcaagacct tcatttgtac
    20101 tattcactga tggagtttcg gcacaacctg atgcttgagt accttgaacc gttagaaaaa
    20161 atgaggattg aggaacagcc gagactgtct gatctgctgc ttgagattga taaaaaacag
    20221 gctcgtttaa ctggtctgct tgagtactat tttaatttct tcagaggcat gtatgagctg
    20281 gatcgccgtg aatatgtatt agccattcaa ttctttaaaa aagctgagag caagctggtt
    20341 tttgtcaaag ataaaatcga taaagctgaa ttctttttca aaatgtcaga agtctattat
    20401 tatatgaaac aaacttatgt ctccatggac tatgcacgtc aagcattcga aatatacagt
    20461 gaacagacta catatgatat cagaatgatt caatgccagt ccttattcgg agccaacttt
    20521 ttggatttaa aacaatacga aaaagcaatt gcccattttc aaaaagcctt tacacttgca
    20581 aaaacagagc agcagcccca attaatggga agaacacttt ataacatagc actctgcaag
    20641 caaaaccaaa acagttttga atcagcgata gagtatgtaa aaaaatctat tcaagtattt
    20701 gaaggatcta aaatgcttcc ttcattgcca caagcttttt tcctaattac acaaatttat
    20761 tttaaattag gtaagattga taacgcctgt gaatatcata aaaaaggaaa agagtattct
    20821 gcagctgcgg gagataccgt gtatctaacg gagtttgaat ttttggaatc tttatacttg
    20881 tctggaccgg atgaggaacg gatagaaaaa tgttttgttt ttcttgaaag taaaatgatg
    20941 tatgcagata ttgaggactt cgcacttgat gttgctaaat attatcatca acaggaaaat
    21001 tacaaaaaag catctcatta ctttttaaag gttgaagaag caagacagca cattcaaggg
    21061 ggggtgaatt tatatgaaat ggaagtataa attattactc gcttgtttag ctgtgagtgc
    21121 tgtatttatc acagtcgaag tatcaaattc atcaacagaa cattttgatg ttgcgcaacg
    21181 cgccatgatc taaaccgccg tccatcggcg gtttttttgt cccctcttta cccagtctcc
    21241 caatccatgc tatgattttt tcaataatct taaaaatagt ggaaatgcag catgtctctg
    21301 gaaagtgtaa aaacccactt tacacagtgg aatcgagaaa atgatgtgac ggagttcgaa
    21361 acatcgagcg cgacagttga acaggcagct gagacaatcg gcgtaagcct gggtagaatc
    21421 gccaagaccc tgtccttcag aggggaagga gatcaggcga ttctgattgt ggcagccggc
    21481 gatgccaaga tcgacaacaa aacgtacagg caacatttgg ctttaaagca agaatgctct
    21541 ctcccaatga ggtactggag cagacaggcc atgaaattgg aggagtttgc ccatttggat
    21601 cggctcatga tc
//
