LOCUS       NZ_RCDD01000005        20993 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Actinokineospora cianjurensis strain DSM 45657 Ga0180969_105, whole
            genome shotgun sequence.
ACCESSION   NZ_RCDD01000005
VERSION     NZ_RCDD01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora cianjurensis
  ORGANISM  Actinokineospora cianjurensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 423661)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 423661)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 102.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003663795.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:08:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,669
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,552
            CDSs (with protein)               :: 6,552
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3, 1 (5S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 10 of 54
            Pseudo Genes (incomplete)         :: 50 of 54
            Pseudo Genes (internal stop)      :: 2 of 54
            Pseudo Genes (multiple problems)  :: 7 of 54
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 401421
            Orig. end                         :: 422414
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RCDD01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20993
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="furan"
                     /region_number="3"
                     /rules="(mmyO or AvrD)"
                     /tool="antismash"
     cand_cluster    1..20993
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(mmyO or AvrD)"
                     /kind="single"
                     /product="furan"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20993
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[10000:10993](+)"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10993
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(mmyO or AvrD)"
                     /neighbourhood="10000"
                     /product="furan"
                     /protocluster_number="1"
     misc_feature    complement(541..556)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.78"
                     /tool="antismash"
     misc_feature    complement(1150..1164)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     misc_feature    1398..1412
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            complement(1975..2751)
                     /locus_tag="CLV68_RS27075"
                     /old_locus_tag="CLV68_5472"
     CDS             complement(1975..2751)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (2-175). E-value: 5.8e-10. Score:
                     31.3. Matches aSDomain:
                     nrpspksdomains_CLV68_RS27075_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681605.1"
                     /locus_tag="CLV68_RS27075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5472"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_121393706.1"
                     /transl_table=11
                     /translation="MSTALVTGASAGLGVEFAEQFAQRGYDVVLVARTEHRLRELATRL
                     TSTYGVRAEVIAQDLSTVDAVPTITRELAARGITVHTLVNNAGFGSAGRFEEIADGRDR
                     DQLMVNVVSLVGLTRALIPQILDGKGAVINVASTAGLQPTPYFATYGAGKTFVLTFSLA
                     LRAELKGRATVLCVCPGPTETQFFDTVEVGRKAAIGGKFMTAQAVVTATLRALDRDRGY
                     LVPGLLNSANAHLTPRRPRKMVAAIAERVSRGVLSG"
     aSDomain        complement(2227..2745)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV68_RS27075_PKS_KR.1"
                     /evalue="5.80E-10"
                     /label="CLV68_RS27075_PKS_KR.1"
                     /locus_tag="CLV68_RS27075"
                     /protein_end="175"
                     /protein_start="2"
                     /score="31.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGASAGLGVEFAEQFAQRGYDVVLVARTEHRLRELATRLTS
                     TYGVRAEVIAQDLSTVDAVPTITRELAARGITVHTLVNNAGFGSAGRFEEIADGRDRDQ
                     LMVNVVSLVGLTRALIPQILDGKGAVINVASTAGLQPTPYFATYGAGKTFVLTFSLALR
                     AELKGRATVL"
     CDS_motif       complement(2677..2739)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV68_RS27075_0001"
                     /evalue="4.30E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="CLV68_RS27075"
                     /protein_end="25"
                     /protein_start="4"
                     /score="13.0"
                     /tool="antismash"
                     /translation="LVTGASAGLGVEFAEQFAQRG"
     gene            2845..3414
                     /locus_tag="CLV68_RS27080"
                     /old_locus_tag="CLV68_5473"
     CDS             2845..3414
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681604.1"
                     /locus_tag="CLV68_RS27080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5473"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_121393707.1"
                     /transl_table=11
                     /translation="MVTQGRPLRADAERSVRAILEAAERVLAANPAASLEQVAEAAGVA
                     RTTVHRRFANRQALVDTLVTTVMDQLDAVIDAANPDTAPPLVALHQVTASVLRLKLGWP
                     FAMTESFAPESKWAERQHHTAARCVTLLARAQSTGHIAPDADLAWTCKVYYALIGEAAH
                     NTTEPDPDLLATKVINTLLHGAGPRP"
     gene            complement(3477..4544)
                     /locus_tag="CLV68_RS27085"
                     /old_locus_tag="CLV68_5474"
     CDS             complement(3477..4544)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /locus_tag="CLV68_RS27085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5474"
                     /product="glycosyltransferase"
                     /protein_id="WP_121393708.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.2e-14,
                     bitscore: 46.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLSVTMIVRDGAATLGRVLEHAGAFCDELVVVDTGSRDDSRAI
                     AKAAGARLAEFPWRDDFAAARNASLDLCRGDWVMWLDADDVVPAASRAAVKELVLDDRL
                     DAVTAPYQYGFDPVTDACVALVPRERLARRVPGLRWVGAVHEVLAVPGDRREYRADLVV
                     EHRPAPGRSRGTRNLDILERVVRQGDRSRRTLFYYARELRDLGRDAEAVDQFTAYLTDP
                     GADWEHHAALLCLADCHAHLGDPHAQLDALHTALRVDSSRAEAHLALGTFHADRDQWPQ
                     ALPYFSAAASTTPPTTGFITLPTYTWRAWDYLSLCLAKLDRHQESITAALHSLRLGNPD
                     RTRLLDNINWSARSI"
     misc_feature    complement(3513..3515)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4541..6205)
                     /locus_tag="CLV68_RS27090"
                     /old_locus_tag="CLV68_5475"
     CDS             complement(4541..6205)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS27090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_5475"
                     /product="hypothetical protein"
                     /protein_id="WP_121393709.1"
                     /transl_table=11
                     /translation="MRRLLGRWGGAGLDFAAGDLRVSAVLRGGVRRWWTSRNLTVGGTV
                     AADCALGVVAESGGVPAIELAHPGRRDVDVDGLDVSYLGDESGVTRYDIWAARRRTRGA
                     ARSQVLRVLTRTPIAPWPDSLPVRLKGDGVLVTAEALSDPVRRTVALAAAIGAGTANAP
                     DDLLADPAANAAVAISESGANQVLAWLCGRGGIKVMARCRWTAVTISVVDDEPILRVQG
                     VLDDDGRAIPVDRVVTCAFTEGRWEVESDSAPPLVLTALSGLVSTLFFAGPAAGDEPRQ
                     RFTVPGTGIHLDAVPVAISGRGRFLVVTYALPPVPVDTRTPRVDPPPRARISSVFRGAP
                     NAITGYRLTAELESGRSGPHDHAWIIDGAARARRGHRRSVTVKPNVRDVRLRVIDMLGK
                     MGETSHGEDEQNRDRDAVAGGAGGRRSGTPTAAILLLGALGAGVVGGVVLAGSQTAETR
                     PGSPGLTGPAGPAGADGTDGADGTDGVDGSGGSVGGVGEPGLRGPIGRDGRLGVTGPTG
                     PTGPTGPPGPPGPPGPTVTITITVPPIDDGPTGEAGG"
     misc_feature    complement(4676..4678)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    6442..6455
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.06"
                     /tool="antismash"
     misc_feature    complement(6442..6456)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.71"
                     /tool="antismash"
     misc_feature    complement(6477..6490)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            complement(6552..7433)
                     /locus_tag="CLV68_RS27095"
                     /old_locus_tag="CLV68_5476"
     CDS             complement(6552..7433)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037627.4"
                     /locus_tag="CLV68_RS27095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5476"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_121393710.1"
                     /transl_table=11
                     /translation="MGKSGGTSRRREELGHFLTTRRARLSPAEIGLSVSSGRRRTPGLR
                     REEVAVLAGIGTSWYTWLEQGRDINVSEPVARAVGHALRLNRSELCYLYQLLGISPPQA
                     GATVGEHPNLDLRQVVDECLPSPALVVDSLWNLVASNRSARLVFGLTDRDRNLLTSFFC
                     REEIWSRYANPDRMARMAVAQFRVSAAGHYDDPIFNNLIRTLCAQSEKFTQLWHTHEVL
                     DARLSSKEVDHPEVGRLSFDTQSWLLDGPDRIRMFLHVPHRMSDTRAKLAALLAAEPHH
                     ADVSAVADRATA"
     misc_feature    complement(7359..7361)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7699..8919)
                     /locus_tag="CLV68_RS27100"
                     /old_locus_tag="CLV68_5477"
     CDS             complement(7699..8919)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1184: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="CLV68_RS27100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5477"
                     /product="MFS transporter"
                     /protein_id="WP_211346780.1"
                     /transl_table=11
                     /translation="MPVRVRGRARLAPGGGMSAGMVRLFAVAAGLAVANIYYAQPLLTA
                     IAAEFGVGSGTASALVTVTTAGYAVGLGLVVPLADILDRRRLVAAMLAAVALIQAAAAV
                     APSMGLLTAVSAVLAPCAVVAPIMVAFAATLAEPARRGQVTGSVMSGVLVGVLLARTGG
                     GLVADLAGSWRAVYAVAAVLMAVLAAVLWRVLPDVRVADRLGYGALLRSVVTIVREEPV
                     LRLRCAYGFLSFAGFSAFWATTAFLLAGEPYHFGPGVIGAFGLLGAVGAVAARVTGRFV
                     DRGRGDVVTGALLGAVLLSWGLMALGGGRWIVPLVLGVVALDLGVQGVQVANLTAVYQL
                     RPEARSRITMAYTGTYFLGGAVGAGASGAAYAAAGWLAVCGVGGLLATAALVLWAVRGR
                     SVRVPPG"
     gene            complement(9097..9507)
                     /locus_tag="CLV68_RS35460"
                     /old_locus_tag="CLV68_5478"
     CDS             complement(9097..9507)
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004559050.1"
                     /locus_tag="CLV68_RS35460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5478"
                     /product="hotdog fold thioesterase"
                     /protein_id="WP_246010139.1"
                     /transl_table=11
                     /translation="MFGIPAQPGHQAEQLIAKLGIRVVECAPGRVVGTMPVSGNRQPVG
                     IMHGGANAAFAETLGSLAAWAHAGTGGRAVGLDLSCTHHRWVSSGLVTGTATALHEGRA
                     TATYEIVIVDDRGRRTCTARLTCAIGRRRRAS"
     misc_feature    9623..9637
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     gene            10001..10993
                     /locus_tag="CLV68_RS27110"
                     /old_locus_tag="CLV68_5479"
     CDS             10001..10993
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) furan:
                     AvrD"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017469.4"
                     /locus_tag="CLV68_RS27110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5479"
                     /product="AvrD family protein"
                     /protein_id="WP_121393713.1"
                     /sec_met_domain="AvrD (E-value: 4.6e-101, bitscore: 332.9,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNPAPPRPTVDDYLGDGDKRFFSAGYRRVGYHFGPVTTEVATAR
                     DAAVRTTVGLTYPTDWSKKSAGVDLRPHLSTIDAILFGVGLAELCVVSAFGADDEARRA
                     MWVRRVRIRAGQSPEEDLRQLPLSARLTETAAEPGGLSTVSTVDCQVGSMRVRCELVHA
                     GGAVRPGKDQYDGPDALLGPAADRYYGTGFARVRHSLEDLSLDVPNTAAEATVRWEPSD
                     ATAGVEGAYQPAPTMVEAFATGLQLAQVLLYEMDGMRRSGSNTLWMRSTTLTATRPAGG
                     TGPLALRTTLANTGLIEMNGGVWRTADIHTDLAGIRFTCAVAHALPRGI"
     gene            11017..11733
                     /locus_tag="CLV68_RS27115"
                     /old_locus_tag="CLV68_5480"
     CDS             11017..11733
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS27115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_5480"
                     /product="AAA family ATPase"
                     /protein_id="WP_121393714.1"
                     /transl_table=11
                     /translation="MKLAISGTYSSGKTLTSYALSHLVDMPRTRARTMRELLPFAVPGK
                     TLEQCDGAELIQLIVRRHVERVVHESHLTTGFVSDGSSLQEWLYGSVRVIVGINPNDSV
                     HLSDVENVERTPEMLFFEHVMDQLGVAIKEHVKNTYDVFVHLPNELELAKDGHRPVNER
                     FRRLADEGIAAAIDELGIPRHVIGGTLVERLEGIVEVLGLTPVTDVHTAIARAQDEYRK
                     VDMTIESDRAWAVASA"
     gene            11763..12755
                     /locus_tag="CLV68_RS27120"
                     /old_locus_tag="CLV68_5481"
     CDS             11763..12755
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0033818 -
                     beta-ketoacyl-acyl-carrier-protein synthase III activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874750.1"
                     /locus_tag="CLV68_RS27120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5481"
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="WP_121393761.1"
                     /sec_met_domain="fabH (E-value: 3e-114, bitscore: 375.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGRAAVLAGVGSAVPEDVVTNDMLATRMDTTDEWIRTRTGIRERR
                     HLARGSATSDLAAEAGRRALKSAGVDSVDAVVLATTTPDHPCPATAPTVAAMLGLGTIP
                     AYDVGAVCSGFLYGLASGAGLIALGTAERVLVIGAEAFTTIIDQTDRSTAPIFGDGAGA
                     VVLSAGDQSQPGALLAFDLGSDGDLADLIIIPGGGSRQRASGIPAAPGDEYMAMRGREV
                     FRHAVLRMTESSRAVLARTGWDVDSVDWLVGHQANVRILRAVAEHLGLAQERAFVNVDR
                     YGNTAAASIPLALDDAAGAGLITPGDRIVLTAFGGGASWGAIALEWPDL"
     gene            12788..13015
                     /locus_tag="CLV68_RS27125"
                     /old_locus_tag="CLV68_5482"
     CDS             12788..13015
                     /NRPS_PKS="Domain: PP-binding (3-69). E-value: 1.7e-15.
                     Score: 49.1. Matches aSDomain:
                     nrpspksdomains_CLV68_RS27125_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="CLV68_RS27125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5482"
                     /product="acyl carrier protein"
                     /protein_id="WP_170224609.1"
                     /sec_met_domain="PP-binding (E-value: 1.9e-13, bitscore:
                     45.2, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTILDLVAEKAELPAAQLDPAHTLEDIGLDSLHLMEIALWVQK
                     EYGVVIAEGELHHEQTVGEAIAFLDTRVGG"
     aSDomain        12797..12994
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV68_RS27125_PP-binding.1"
                     /evalue="1.70E-15"
                     /label="CLV68_RS27125_PP-binding.1"
                     /locus_tag="CLV68_RS27125"
                     /protein_end="69"
                     /protein_start="3"
                     /score="49.1"
                     /tool="antismash"
                     /translation="TILDLVAEKAELPAAQLDPAHTLEDIGLDSLHLMEIALWVQKEYG
                     VVIAEGELHHEQTVGEAIAFL"
     gene            13012..13683
                     /locus_tag="CLV68_RS27130"
                     /old_locus_tag="CLV68_5483"
     CDS             13012..13683
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR01490.1"
                     /locus_tag="CLV68_RS27130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5483"
                     /product="HAD-IB family hydrolase"
                     /protein_id="WP_121393716.1"
                     /transl_table=11
                     /translation="MTRAAFFDVDGTLITVTSLFRFLAFDRAQAEYESVMAGLAGVKAA
                     GATREEANRFFYRAFAGRPAADLAALGERWFTAEYARGGLFDPRVLTMLRAHRAAGDTV
                     VLLSGSFGPCLTPIARYACADAVVCTEPEVVSGVLSGVVEVPMVGPNKAVAARRFAEEH
                     GVDLADSFAYGDDISDLPVLDLVGCPVVVGGDPVLRAHAERVGWRRIPAHTREEVLCPS
                     R"
     gene            13680..14624
                     /locus_tag="CLV68_RS27135"
                     /old_locus_tag="CLV68_5484"
     CDS             13680..14624
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (20-309). E-value: 6.4e-44.
                     Score: 142.3. Matches aSDomain:
                     nrpspksdomains_CLV68_RS27135_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801290.1"
                     /locus_tag="CLV68_RS27135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5484"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_121393717.1"
                     /sec_met_domain="ADH_N (E-value: 8.1e-08, bitscore: 26.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.1e-10, bitscore:
                     33.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVVQTVAAGGPEVLVSTVVPRPVPVPTEVLVRVHAAGVNPVDWK
                     IRGGVFPSGALGAHPFTQGWDVAGVVEAGPRVTRFQPGDEVFGLLWFPRQAGGYGEYVT
                     APARQFARKPESLSFTEAAALPMAGLTAWQTLVDVAGIGEGSRVLITAAAGGVGHLACQ
                     VARSRGAVVTGTASAAKHDFLASVGVHEAVDYTRVEVGTAVRDQDVVLDLLGGDHTLGL
                     LDTLRPGGLLVLTIGQISPEVAAAAKTRGVRVSPFLVEPDSAGLEALTALVERDALRVH
                     VDHVLPLAEAGKAHELGETNRTTGKIVLSVTGT"
     aSDomain        13740..14606
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CLV68_RS27135_PKS_ER.1"
                     /evalue="6.40E-44"
                     /label="CLV68_RS27135_PKS_ER.1"
                     /locus_tag="CLV68_RS27135"
                     /protein_end="309"
                     /protein_start="20"
                     /score="142.3"
                     /tool="antismash"
                     /translation="PRPVPVPTEVLVRVHAAGVNPVDWKIRGGVFPSGALGAHPFTQGW
                     DVAGVVEAGPRVTRFQPGDEVFGLLWFPRQAGGYGEYVTAPARQFARKPESLSFTEAAA
                     LPMAGLTAWQTLVDVAGIGEGSRVLITAAAGGVGHLACQVARSRGAVVTGTASAAKHDF
                     LASVGVHEAVDYTRVEVGTAVRDQDVVLDLLGGDHTLGLLDTLRPGGLLVLTIGQISPE
                     VAAAAKTRGVRVSPFLVEPDSAGLEALTALVERDALRVHVDHVLPLAEAGKAHELGETN
                     RTTGKIVL"
     CDS_motif       14112..14174
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CLV68_RS27135_0001"
                     /evalue="9.10E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="CLV68_RS27135"
                     /protein_end="165"
                     /protein_start="144"
                     /score="15.1"
                     /tool="antismash"
                     /translation="GSRVLITAAAGGVGHLACQVA"
     gene            14748..16283
                     /locus_tag="CLV68_RS27140"
                     /old_locus_tag="CLV68_5485"
     CDS             14748..16283
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020662507.1"
                     /locus_tag="CLV68_RS27140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5485"
                     /product="MFS transporter"
                     /protein_id="WP_246010133.1"
                     /transl_table=11
                     /translation="MSTTVSPATSRATATITLIAVCVSCGLLPASLTGTSIALPDIGSD
                     LGADLVSVQWVVNAYNLAFASVMLAAGAVADLVGRKRMFGIGLVVFLACTAGVAAVSDI
                     VLVDVLRALAGVGAAMVLTAASALLAQAFDGPARLKAFGLLGSSFGLGLALGPSTSGML
                     VSLWGWRAVFLAHAVIAAAVLFALPALRESRDPDATGVDWPGTTTFSGALVALTLALVE
                     GPQRGWGDGLVLALFVVFAVLIAAFVAVERRQARPMFDLGLFRQPRFVAVCLMPVLLAF
                     GFVCLLVFLPSFFIGITGMGARQAGLTMLLLTVPVLVFPVVAGTLAKTIPARVLLGVSL
                     LLVAAGAAWLTVIDRDATAGTLIGPLLVIGTGVGISFGLLDGAAIGSVDPARAGMAAGM
                     FNTMRLTGEAVAIAGMGSLLVSLTRGGLGGLTDYPAAGAVGEVANKVAQGEVASVAARV
                     GETQRAAFVDFVSGSYTSAFHTVLWILAAVCALGAPVIAVMLRERPVPNPVEA"
     gene            16285..17802
                     /locus_tag="CLV68_RS27145"
                     /old_locus_tag="CLV68_5486"
     CDS             16285..17802
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="CLV68_RS27145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5486"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_121393718.1"
                     /transl_table=11
                     /translation="MSEKSPVLVVGAGPVGLTAAVELARRGVPVRLVDRAAEPSPLTKA
                     LMVWPRTLEVFRLLGGSEHLDTYGLPVQAFRYYSESSEVCKLAFDAETKPSVVTQPDVE
                     ALLRKSLADAGGVIEWETTATALRHDDTGVEATITAPDGTSAVERFAYLIGADGAGSLV
                     RKQIGLEFHGATYPNVFILADVSLDGDLQRDAVHYYCSSKGIMVLIPLYNGRFRVFTAG
                     PPGMKPEELTEQVLQDYVDLRGPGGLRTHDVSWKTTFSIHARHTERLRVGRVFLAGDAA
                     HVHSPAGGQGLNTGVTDAHNLAWKLALVHQGKAAPELLDTYEVERRSVAAAVVRQAEVQ
                     TKAWMLKKRWQIRSRDLAAGLAEKLGLFDRYYSPWLAGLTNHYPENPAVSGPVAKRAGA
                     KRDRLLSGYLAPAALRAVLPTDRYTLVVHGSTTAADQLARRYPDLLAVREVSAEGVLPD
                     AEGTPVAVAWRPKRPLAALVRPDGYVAAVDRTPDLPTLRAHLTAVRG"
     misc_feature    complement(17821..17835)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.15"
                     /tool="antismash"
     gene            17829..18242
                     /locus_tag="CLV68_RS27150"
                     /old_locus_tag="CLV68_5487"
     CDS             17829..18242
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024092.4"
                     /locus_tag="CLV68_RS27150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5487"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_121393719.1"
                     /transl_table=11
                     /translation="MSTPVTTRDTAATIGEFFARFGAGDRPGMLELFAEGAELAVAGAD
                     TVPWTGVRTEAAAIDEFLRIALEDVSTEVFTVDKIIVDGEDGVVLGSLAHRITATDRVF
                     ASAFALHIHVVDGLIASYRMFEDSHAAEVSWTR"
     gene            complement(18357..19217)
                     /locus_tag="CLV68_RS27155"
                     /old_locus_tag="CLV68_5488"
     CDS             complement(18357..19217)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015098423.1"
                     /locus_tag="CLV68_RS27155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5488"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_121393720.1"
                     /transl_table=11
                     /translation="MDDRNELGRFLKSRRARVDPADVGIEVLARRRVAGLRREEVASLA
                     GISVEYYVRLEQGRASRPSESVLESLARALALDDVERRYLDELVRPRPVASRGPRPERA
                     RPELAQLLSFLDRVPALVINHRMDVLAWNHLSCQLFLDFAAATPRQRNLARFGFLDADS
                     QQRFVDWQDVCRATAGSLRLAAGRHTHDEALATLIGELTMKSELFRTLWAGRDVKQRTH
                     GSKRFRHPVVGELVLRFENFDLPGETDQRLVTFSPEPASPAEQALSLLAMWSTPAPARV
                     EEPTG"
     gene            19352..20098
                     /locus_tag="CLV68_RS27160"
                     /old_locus_tag="CLV68_5489"
     CDS             19352..20098
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013866.4"
                     /locus_tag="CLV68_RS27160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5489"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_121393721.1"
                     /transl_table=11
                     /translation="MCHSTDSRPPALDNPGEVAEEGLLELTSADGTAFSAFRAIPAEPN
                     GINIVILPDIRGTHPYYQALANRFAQAGYTTAAIDYYGRTAGPGVRDDKFEWQPLLPQV
                     KAEEVAADVRAAATYLEQHNTGPVFTVGFCFGGGQSWRLSAGDLGVAGVIGFYGLPKLV
                     NDVVDDISAPLLLLLAGEDVATSQEEFKEFAGKLDAAGKDYDLHVYEGAPHSFFDASYD
                     EWQEACADAWERVVGFIQKHSAPVAV"
     gene            20098..20511
                     /locus_tag="CLV68_RS27165"
                     /old_locus_tag="CLV68_5490"
     CDS             20098..20511
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014664.4"
                     /locus_tag="CLV68_RS27165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_5490"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_121393722.1"
                     /transl_table=11
                     /translation="MPTERFRRGAARLAEMGGDIDNIVAPLADVAPDLARLVGEFAFGD
                     LYTRPGLDLPRRQLVTIAALVTLGDTERQLRFHIAAALEVGVTPQQVVETIIHLLAFAG
                     NPRVFNAMLVAKAVFAERGLLPLTDQPPVDPAG"
     gene            complement(20594..20911)
                     /locus_tag="CLV68_RS27170"
                     /old_locus_tag="CLV68_5491"
     CDS             complement(20594..20911)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS27170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_5491"
                     /product="hypothetical protein"
                     /protein_id="WP_121393723.1"
                     /transl_table=11
                     /translation="MRSATRIALGVLFACVLATQAVTPAAAARGTFTFYDDDGGAGIVN
                     PSDNVCYPLGTTIRRVENRTDRQAVLYLSADCVGKSALVLAPRKSRDIKVAAVMFTRTR
                     R"
     misc_feature    20880..20895
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.92"
                     /tool="antismash"
ORIGIN
        1 ctgagtacgc gcgcctgggc ggtggtcggg cgttcctgtg gccggggttg gggatcggcc
       61 tcgggctggg actcggcggg ctggtcgtgc cgatggtcgt cctcgacccg atgggactcc
      121 acttcgcccc gctgaccctg gtgttgcggg ccgtcggcgt ggtcgtggcg gtgctggtgt
      181 gcgcgtgggc cacctggtgc gtgtcgctcg ccaggaccaa ggtccaccgg gccgcggtgg
      241 ccctcgcggt attcgttgtg tgctggagct gtctggggtg gctgcccaac gcgtacgggt
      301 acgccgggct gtgggactcg atgatcgtcc ccgcgttcga acggctcggt gacctggcgg
      361 gcgggggagc ggacgcggtg gtcgtcgggg ccgcgtccgt cgcgctgttc gcggacgcgg
      421 accgggcatt ggcgacgatc gcgctcggct tggtgtggct cgtaccggcg ctcctgggcc
      481 gtccgccgcg ggcagcgttc atcgtgggcg cggcgggtat gggtgtggcg gcgttggccg
      541 tgttcgcgat cggcggctcg gacccgctgg tggcgaccgc gtggcaactg gtggcgatcg
      601 ccgtcgtcca actcgtggcc gcgtgggtgg cgcgccgggc cggggtcgtc gcggctgtgg
      661 tggcggcctg gttgacgggc gtggcggggt gcgtggcgat ctggggcgcg cactggtcgg
      721 ctggcggggt cgacgcggtc ctggccaggc aaccgatgcg gatcctgccg ttcaccgccc
      781 tcgtcgccgc ggccctggtg gtcgtggcgg gacgcctagc ggcgtcgcgt cgggtgggcc
      841 ctcgtgacgg gatggcgtcg tcgtctggct cggtggttgg gtcgcgggcg gtggcgatgg
      901 ggggtggtgg gcggaactcc tggtgggcgg cgtcggtgtc gcgggtggtg ttggtccctg
      961 ttgtcgtgct gaccgcggtc gtggtggttc cgttcccggt gaccacgtcg tccgctgtgg
     1021 cgttgttgcc gccgcagcca acggtcgggc ttgtcgaccc gcagcgggcg ttgttcatct
     1081 ggtcgcacgg tgggggagtg gcgctgctca acgacgtcgt gcaggcgcag tcgcgggcgt
     1141 tcttcgggat ggccgaggac gaccgggcgg cgcaggtggc gcggtgcggg gagttgctgg
     1201 accggatccg ggtggcccgc gagtacccgg atccgccgga gccggtcgcg cgcgggcact
     1261 gggagtccgg aatggacgct tcgcggaatg gtgccgagga gtgcacgcgg atcttcgccg
     1321 gacccgaggg tgacccgaat ccggtctcga tcgctttcac cgcggccaat gccgacttcc
     1381 gacccctgct gcgggcgatc tcgggtgtcg acgccgacgt cccacccgag ccgcccgcgc
     1441 cgaccaccag cacgccgccg ccacccccgc cgcccccggt cgacctggcg acgatgctgc
     1501 tcacgaccgc cgacctgccg cgcggcgcca aggagaagcc gccatcgacc ggagggtcct
     1561 cttcggacat ccggaccgag ccgtcggact gcggggtgga cgtcgggccg cctgagctcg
     1621 ccaaggcgtc gcggacgttc gacatgcccg acgggtcgtg gatcaccgcc tcggtctacc
     1681 gctatcccga cgacgacggt ggggtgacgt tgcggatgat ggccgagagc tacgtgcact
     1741 gctaccagta ccgcgtgttc gcgggcgaca tcacgcagaa ggtcaccatc gacgtcgtca
     1801 gcggcgcacc cctggtcgcg gacatcacct tcgacggtgg cttcgtggtg ttccactcgc
     1861 gccaggtgtg gatcctcaag ggcgagttgt tggcctgcgt cagtgtcggg ggcaagcgca
     1921 ggcccgatcc gtcgcttgtg gactccctgg cggcgaccgt gaccgggcgg ctggtcaccc
     1981 gctgagcacg ccgcgcgaca cccgctcggc gatggcggcg accatcttgc gcgggcggcg
     2041 cggggtgagg tgcgcgttgg cggagttgag gagtccgggc accaggtagc cgcggtcgcg
     2101 gtcgagggcg cgcagggttg cggtgacgac ggcttgcgcg gtcatgaact tgccgccgat
     2161 ggccgccttg cgcccgacct cgacggtgtc gaagaactgg gtctcggtgg ggcccgggca
     2221 gacacagagg acggtggcgc ggcccttgag ttcggcgcgc agggcgaggc tgaaggtgag
     2281 cacgaacgtc ttgcccgcgc cgtaggtggc gaagtacggg gtcggttgca ggcccgcggt
     2341 ggaggcgacg ttgatcaccg cgcccttgcc gtcgaggatc tgcgggatca gggcgcgggt
     2401 cagcccgacc aggctgacga cgttgaccat caactggtcc cggtcgcggc cgtcggcgat
     2461 ctcctcgaag cggccagccg agccgaagcc cgcgttgttg accagggtgt gcacggtgat
     2521 gcccctggcc gccagttcgc gggtgatcgt cgggacggcg tcgacggtgc tgaggtcctg
     2581 ggcgatcacc tcggcccgca cgccgtaggt gctggtgagg cgcgtggcga gctcgcggag
     2641 gcggtgctcg gtgcgggcga cgagcacgac gtcgtagccg cgttgggcga actgctcggc
     2701 gaactcgacc cccaggcccg ctgacgcgcc ggtgaccagt gctgtgctca tcgtggctct
     2761 ccctctgctc ggctaactgc atcacagttg tagcagatta gcggctagat gcaacagagg
     2821 tgtcgcagat gttagggtgg cggggtggtc acccagggac gcccgctgcg cgccgacgcc
     2881 gaacgcagcg tccgcgcgat cctggaggcg gcggagcggg tactggcggc gaacccggcc
     2941 gcgtccctgg aacaggtcgc cgaggccgcg ggcgtcgcca ggaccaccgt ccaccgccgc
     3001 ttcgccaacc gccaggccct cgtcgacacc ctggtcacca ccgtcatgga ccaactcgac
     3061 gcggtgatcg acgcggccaa ccccgacacc gcgcccccgc tggtcgccct gcaccaggtc
     3121 accgccagcg tcctgcgcct caaactcggc tggcccttcg ccatgaccga gtccttcgcc
     3181 cccgagtcca aatgggccga acgccaacac cacaccgccg cccgttgcgt gaccctgctg
     3241 gcccgagccc agtccaccgg ccacatcgct cccgacgccg acctggcctg gacctgcaag
     3301 gtctactacg ccctcatcgg cgaagccgcc cacaacacca ccgaacccga ccccgacctc
     3361 ctcgccacca aggtcatcaa caccctcctg cacggcgccg gtccgcggcc ctgaccccgg
     3421 ccccaggtct tcacgtaagc agcttgggtt ctagcgagag ttcgccgaac tcagtcctaa
     3481 atggaccgtg cggaccagtt gatgttgtcg agtaaacgtg tgcggtcggg gttgccgagg
     3541 cggagggagt ggagggcggc ggtgatgctc tcctggtgtc tgtccagttt ggccaggcag
     3601 aggctcaggt agtcccacgc ccgccaggtg taggtgggga gggtgatgaa gccggtggtg
     3661 gggggtgtgg tggaggcggc ggcggagaag tacgggaggg cttggggcca ctggtcgcgg
     3721 tcggcgtgga aggtgcccag ggccaggtgg gcctcggcgc gggaggagtc gactcgcagg
     3781 gcggtgtgga gggcgtcgag ttgggcgtgc gggtcgccga ggtgggcgtg gcagtcggcc
     3841 aggcacagca gggccgcgtg gtgttcccag tccgcgcccg ggtcggtcag gtacgcggtg
     3901 aactggtcca ccgcctccgc gtcgcggccc aggtcccgga gctcgcgcgc gtagtagaac
     3961 agcgtgcggc gcgagcgatc accttgccgc acaacgcgtt ccaggatgtc gaggttgcgc
     4021 gtcccccggg aacgcccggg cgcgggccgg tgttcgacca ccaggtccgc gcggtactcc
     4081 cggcgatccc ccggcaccgc cagcacctcg tgcaccgcgc ccacccaccg cagaccgggc
     4141 acccggcgcg cgaggcgttc ccgggggacc agcgccacgc acgcgtcggt gaccgggtcg
     4201 aagccgtact ggtacggggc ggtcaccgcg tcgagccggt cgtcgagcac caactccttg
     4261 accgccgcac gggacgcggc gggcacgacg tcgtccgcgt cgagccacat gacccagtcg
     4321 ccgcggcaca ggtcgaggga ggcgttgcgc gcggcggcga agtcgtcgcg ccacgggaac
     4381 tccgcgagcc gggcgcccgc ggccttggcg atcgcccgcg agtcgtcccg cgacccggtg
     4441 tcgaccacca ccagctcgtc gcagaaggca ccggcgtgct ccagcacccg ccccagcgtc
     4501 gccgccccgt cccggacgat catggtgacc gacagcgagg tcatccgccc gcctccccgg
     4561 tcggcccgtc atcgatcggc ggcacggtga tcgtgatggt caccgtgggc ccaggcggac
     4621 cgggaggccc aggaggacca gtcggcccgg taggccccgt cggcccggtc acgcctaacc
     4681 tgccgtcacg gccgatagga ccgcgcagcc ccggttcgcc cacacctccc actgacccgc
     4741 ctgacccatc gacgccgtca gtgccatccg cgccgtctgt cccatcggca cccgcgggac
     4801 cagccggacc cgtgagaccg ggactgcctg gtcgtgtctc cgcggtctgg gagcccgcca
     4861 ggacgacgcc tcccacgaca cccgccccca acgcgccgag gagcaggatc gcggcggtgg
     4921 gcgtcccgga tcgccgccca cctgccccac cggccacggc gtcccgatcc cgattctgct
     4981 cgtcctcgcc gtggctggtc tcgcccatct tccccagcat gtcgatcacg cgcagccgga
     5041 cgtcgcggac gttcggcttg accgtcaccg accggcggtg cccacgacgc gcccgcgcgg
     5101 ccccgtcgat gatccaggcg tggtcgtgcg gcccggaccg cccgctctcc agctccgcgg
     5161 tgagccggta cccggtgatg gcgttgggcg cgccgcggaa cacggagctg atccgcgccc
     5221 gcggcggcgg gtccacgcgc ggggtccggg tgtcgaccgg gacgggcggg agcgcgtacg
     5281 tcacgaccag gaacctgccc cgcccggaga tcgccaccgg taccgcgtcg aggtggatgc
     5341 cggtgccggg aacggtgaac cgctgccgcg gctcgtcccc ggcagcggga ccggcgaaga
     5401 acagcgtgga caccagcccg ctgagcgcgg tgagcaccag cggcggcgcc gagtcggact
     5461 cgacctccca ccgcccctcg gtgaacgcgc aggtgaccac ccggtcgacg gggatcgccc
     5521 gcccgtcgtc gtccagcacg ccctggaccc gcaggatcgg ctcgtcgtcg accacgctga
     5581 tggtcaccgc ggtccaccgg caccgcgcca tgaccttgat cccgccccgc ccgcacagcc
     5641 aggccagcac ctggttggcg ccggactcgc tgatcgcgac cgccgcgttc gccgccgggt
     5701 cggcgagcag gtcgtccggc gcgttcgccg tgcccgcgcc gatcgcggcg gccagcgcca
     5761 ccgtgcgccg gaccgggtcc gacagcgcct cggccgtcac caggacgccg tcgcccttca
     5821 gccgcaccgg gagcgagtcg ggccacggcg cgatcggcgt gcgggtcagc acccgcagca
     5881 cctgggaccg cgcggcgccc cgcgtcctgc gccgggccgc ccagatgtcg tacctggtca
     5941 cccccgactc gtcaccgagg tagctcacgt cgagtccgtc gacgtcgacg tccctcctgc
     6001 ccgggtgggc cagctcgatc gcgggcacgc ccccggactc ggccaccacg cccagcgcgc
     6061 agtcggccgc caccgtgccg ccgacggtga ggttgcgcga ggtccaccag cgccggacgc
     6121 cgccgcgcag cacggcggag acccgcaggt cgcccgccgc gaagtcgagc ccggcgccgc
     6181 cccaccgccc cagcagcctg cgcaccggga aacgcaaccg gacgatccgg ctgaatggtg
     6241 gtcggttgtc cgccccccac gaatgtcgaa gcgtgtgcga ctgaacatct cgaagtgcgt
     6301 cgatggtgaa ctggacaatg acgtcgctgt cgcgcatagc gcctggtccc acccctgctc
     6361 gcccaacccc cgatggtgtg acgagcatac cgccgcacaa ggtgggcgag taattcgggc
     6421 gccttttccg caccggtacg gaattgacaa gaaaatggcc ggtgaatgtc atcgacttgt
     6481 tctggaccga tcgagtgtgc cggtgtttcg ccccccgcct gggcaggggg atgacccctg
     6541 cccaggcgcg atcacgcggt ggctcggtcc gccaccgcgc tgacgtcggc gtggtgcggt
     6601 tcggcggcga gcagggcggc cagcttggcc ctggtgtcgg acatccggtg cggcacgtgc
     6661 aggaacatcc ggatccggtc cgggccgtcg agcagccagg actgggtgtc gaagctcagc
     6721 ctgccgacct cggggtggtc gacctccttg ctgctgagcc gggcgtcgag cacctcgtgg
     6781 gtgtgccaga gttgggtgaa cttctcgctc tgcgcgcaca gcgtgcggat caggttgttg
     6841 aagatcgggt cgtcgtagtg gcccgcggcg ctgacccgga actgggccac cgccatccgg
     6901 gccatccggt cggggttggc gtagcgcgac cagatctcct cgcggcagaa gaagctggtc
     6961 agcaggttgc ggtcgcggtc ggtcaggccg aacaccagcc gcgcggagcg gttgcttgcc
     7021 accaggttcc acaggctgtc gaccaccagc gccgggctgg gcaggcactc gtcgaccacc
     7081 tgccgcaggt ccaggttcgg gtgctccccc accgtcgccc cggcctgcgg cgggctgatg
     7141 cccagcagtt ggtagaggta gcacaactcc gagcggttga gccgcagcgc gtgccccacc
     7201 gcgcgcgcca ccggctcgga gacgttgatg tcgcggccct gttcgagcca cgtgtaccag
     7261 gacgtgccga tgcccgcgag caccgcgacc tcctcgcggc gcaagcccgg cgttcgccgt
     7321 cttccggatg atacggacaa accgatttcg gcaggcgata atcgagcccg gcgcgtcgtc
     7381 aggaaatgcc ccaactcctc gcgacgcctg ctggtccccc cactctttcc catgttcgga
     7441 gttttgccac tttcccagtc gggtgtcaag cggtaccgca cgaggtgatc atgcgattac
     7501 cggccgtgca agtgagtgcc gctcaccggc gagttcgttg agcggccaac gatttcggat
     7561 gcaaagaaac tgatcggtag ggtggggtcg gcgggaatcc gaaagcagtc tccgggcgtg
     7621 gcgagttgct tctcggcgcg ttctgcgcaa ttgccgcaga agtggtggcg aaacctgttc
     7681 gtgatcggtt ccgacgtgtt acccgggtgg gacgcggacc gatcggccgc gcacggccca
     7741 cagcaccagc gccgccgtgg ccagcagtcc gccgacgccg cacaccgcga gccagcccgc
     7801 cgcggcgtat gcggcaccgg aggcgcccgc gcccaccgcc ccgccgagga agtaggtgcc
     7861 ggtgtaggcc atggtgatcc ggctgcgcgc ctcgggccgc agctggtaga cggcggtcag
     7921 gttcgccacc tggacgccct gcacccccag gtcgagcgcc accaccccga gcacgagcgg
     7981 cacgatccac cgcccaccgc ccagcgccat cagcccccac gacagcagga ccgcgcccag
     8041 cagcgccccg gtgaccacgt cgccgcggcc ccggtcgacg aaccggccgg tgacccgcgc
     8101 cgcgaccgcg cccaccgctc ccagcaggcc gaacgcgccg atcacgcccg gcccgaagtg
     8161 gtagggctcc ccggcgagca ggaacgccgt cgtcgcccag aacgcgctga acccggcgaa
     8221 ggacaggaac ccgtaggcgc agcgcagccg cagcaccggt tcctcgcgca cgatcgtcac
     8281 caccgagcgc agcagcgcgc cgtagccgag ccggtcggcg acccgcacgt ccggcagcac
     8341 ccgccacagc accgcggcca ggaccgccat cagcaccgcg gccaccgcgt agaccgcccg
     8401 ccacgacccg gccaggtcgg cgaccaggcc gccgccggtg cgggcgagca gcaccccgac
     8461 cagcacgccg ctcatgaccg acccggtgac ctggccccgc cgcgccggtt cggccagggt
     8521 cgccgcgaac gccaccatga tcggcgcgac caccgcgcac ggcgccagca ccgcggagac
     8581 cgccgtgagc aggcccatcg acggcgcgac cgcggcggcg gcctggatga gcgccaccgc
     8641 ggccagcatg gccgccacca ggcgcctgcg gtcgaggatg tcggccagcg gcacgacgag
     8701 cccgaggccg acggcgtacc ccgcggtggt gaccgtgacc agcgccgacg ccgtgccgct
     8761 gccgaccccg aactcggcgg cgatggcggt cagcagcggc tgcgcgtagt agatgttggc
     8821 gaccgcgagc ccggccgcga ccgcgaagag ccggaccatg cccgcggaca tgcccccgcc
     8881 cggcgccaac cgcgcccggc cccgcactcg aacaggcact tctgcaggca cttcactcca
     8941 gcgggtagct caaggacggg cccccacccg ttgatcaccc acgatggtcg cgcacccggc
     9001 cccaccggta ccaggggtgt gccaatccct ccccctgccg gtactggtac cgccagggcc
     9061 acccgtccac tgtggatgat gggacgaccg gacgggtcag ctcgcgcgcc tgcgcctgcc
     9121 gatggcgcag gtcaaccgcg cggtgcaggt gcgcctgccg cggtcgtcga cgatcacgat
     9181 ctcgtaggtg gcggtggcgc ggccctcgtg cagcgcggtg gcggtgccgg tgaccaggcc
     9241 cgaggacacc cagcggtggt gggtgcagga caggtcgagc ccgacggcgc ggccaccggt
     9301 gcccgcgtgc gcccaggcgg ccagcgagcc gagcgtctcg gcgaaggccg cgttggcgcc
     9361 gccgtgcatg atcccgaccg gctgccggtt gccgctgacc ggcatcgttc cgaccacccg
     9421 ccccggcgcg cactccacga cgcggatgcc gagcttggcg atcagctgct cggcctggtg
     9481 gcccggctgc gccgggatgc cgaacagcgc ggggatgtcg gacaggtctg ccgcggcagg
     9541 cgggtgtggt gcggcaggcg ggtgtggtgc ggcggaaagg tcggttgtca ccggggacct
     9601 cctggttggt gcggaccgaa tgggacgtat tcggacactc cggccacggt ggacggacac
     9661 acgcgactgc cgcgctgtgc gcgggtttac cggcggtttg atcgccgtgg tgttgcccgt
     9721 ggacaccggg gcctccaggc tgggacctcg cgccaccgcg ctgccatcgg ttgtggcaca
     9781 ggtcatcctg gtgttcgcgg tacccggttg gttgtacccg gatggcggta cccgtacaaa
     9841 gcgacgcagg ctcagccccc cgccgccggg gtagcgttga tcttgacagc ggccgtcgag
     9901 ctcgccccca ggcgatccgg tgctgtcccg acgcacgtct tctcgttccc caccagcgca
     9961 cgcggaccgc ctcggcgacc gcggacggga gtgtcccaag atgaccaacc cagcgccgcc
    10021 gcgcccgacg gtcgacgact acctcggcga cggcgacaag cgcttcttct cagcgggtta
    10081 ccgcagggtc ggctaccact tcggaccggt caccaccgag gtcgccaccg cgcgggacgc
    10141 ggcggtgcgc accaccgtgg gcctcaccta tccgaccgac tggtcgaaga agtccgcggg
    10201 tgtggacctg cggccgcacc tgagcaccat cgacgccatc ctcttcggcg tcggcctcgc
    10261 ggaactgtgc gtggtcagcg ctttcggcgc ggacgacgag gcccgcaggg cgatgtgggt
    10321 gcgccgggtg cggatccggg ccgggcagag ccccgaggaa gacctgcggc agctgcccct
    10381 ctcggctcgg ctgaccgaga ccgccgccga accgggtggt ctctccactg tctccactgt
    10441 ggactgccag gtcggctcga tgcgggtccg gtgcgaactc gtccacgcgg gcggcgcggt
    10501 tcggccgggc aaggatcagt acgacggccc ggacgcactg ctcggtccgg cggccgatcg
    10561 ctactacggc accggtttcg cacgggtccg gcacagcctc gaagacctct cgctggacgt
    10621 gccgaacacc gcggccgagg cgaccgtccg gtgggaaccg tccgacgcca ccgccggggt
    10681 cgagggcgcc taccagcccg cgccgaccat ggtggaggcg ttcgccaccg ggctccagct
    10741 cgcgcaggtc ctgctctacg agatggatgg tatgcgccgc agcgggagca acacgctgtg
    10801 gatgcgttcc accacgctca ccgccacccg ccccgcgggc ggcaccggac cgctcgccct
    10861 gcgcaccacc ctggccaaca ccggcctcat cgagatgaac ggcggcgtct ggcgcaccgc
    10921 cgacatccac accgacctgg cgggcatccg cttcacctgc gccgtcgcgc acgcgctgcc
    10981 ccgcggcatc tgacccactc cactaaggac acttccatga agctcgccat ctccgggacc
    11041 tactcctccg gcaagaccct cacctcgtac gcgctctcgc acctggtcga catgccgcgc
    11101 acccgcgccc gcaccatgcg cgagctgctg ccgttcgccg tcccgggcaa gaccctggag
    11161 cagtgcgacg gcgccgagct gatccagctc atcgtgcgca ggcacgtcga gcgcgtcgtg
    11221 cacgagagcc acctcaccac cgggttcgtc tcggacggtt cgtcgttgca ggagtggctc
    11281 tacggctcgg tccgggtgat cgtcggcatc aaccccaacg actccgtgca cctctccgac
    11341 gtcgagaacg tcgagcgcac ccccgagatg ctgttcttcg agcacgtcat ggaccagctc
    11401 ggcgtcgcca tcaaggagca cgtcaagaac acctacgacg tgttcgtgca cctgcccaac
    11461 gagctggagc tggccaagga cgggcaccgc ccggtcaacg agcgcttccg caggctcgcc
    11521 gacgagggca tcgccgcggc catcgacgag ctgggcatcc cgcgccacgt catcggcggc
    11581 accctggtcg agcggctgga gggcatcgtc gaggtgctcg gcctgacccc ggtcaccgac
    11641 gtgcacaccg ccatcgcccg cgcgcaggac gagtaccgca aggtcgacat gaccatcgag
    11701 tccgaccgcg cgtgggccgt ggcgtcggcc tgagccgggc gcgcgtgggg gaggacaggc
    11761 tgatgggacg tgcggccgtg ttggcaggcg tcggctcggc ggtgccggag gacgtcgtca
    11821 ccaacgacat gctcgccacc aggatggaca ccaccgacga gtggatcagg acgcggaccg
    11881 gcatccgcga gcgcaggcac ctggcccgcg ggtcggcgac cagcgacctg gccgcggaag
    11941 cggggcggcg ggcgttgaag tctgccgggg tcgactcggt ggacgccgtg gtgctggcca
    12001 ccaccacacc cgaccacccg tgcccggcga ccgcgccgac ggtggccgcg atgctggggc
    12061 tcgggaccat cccggcctac gacgtcggcg cggtgtgctc cgggttcctc tacggactcg
    12121 cctccggtgc cgggctcatc gcgctcggca cggcggagcg ggtgctggtg atcggcgccg
    12181 aggcgttcac cacgatcatc gaccagaccg accgcagcac cgcgccgatc ttcggcgacg
    12241 gcgcgggcgc ggtggtgctc agcgcgggcg accagtccca acccggcgcg ctgctggcct
    12301 tcgacctcgg cagcgacggc gacctcgccg acctgatcat catccccggc ggtggttccc
    12361 ggcagcgcgc ctccgggatc cccgccgcgc cgggcgacga gtacatggcg atgcgcggcc
    12421 gggaggtgtt ccggcacgcg gtgctgcgga tgaccgagtc ctcccgcgcc gtgctggccc
    12481 gcaccggctg ggacgtcgac tcggtcgact ggttggtcgg gcaccaggcg aacgtgcgca
    12541 tcctgcgcgc ggtcgccgaa cacctggggc tggcccagga gcgggccttc gtcaacgtcg
    12601 accgctacgg caacaccgcg gccgcctcga tcccgctcgc cctcgacgac gcggcgggcg
    12661 ccgggttgat caccccgggc gaccggatcg tcctgaccgc cttcggcggc ggcgccagct
    12721 ggggcgcgat cgccctggaa tggccggacc tctgaccaca ccggacagtc acctcaagga
    12781 gagcacgttg aacaccacca tcctggacct ggtcgcggag aaggcggaac tgcccgccgc
    12841 gcagctggac ccggcgcaca ccctggagga catcgggctg gactcgctgc acctgatgga
    12901 gatcgcgctg tgggtgcaga aggagtacgg ggtcgtcatc gccgagggcg agctgcacca
    12961 cgagcagacc gtgggcgagg ccatcgcctt cctcgacacc cgcgtcggcg gatgacccga
    13021 gcggcgttct tcgacgtcga cggcacgctc atcaccgtca ccagcctgtt ccggttcctc
    13081 gccttcgacc gcgcgcaggc cgagtacgag tcggtgatgg ccgggttggc cggggtcaag
    13141 gcggcgggcg cgacgcggga ggaggccaac cggttcttct accgggcctt cgccggtcga
    13201 cccgccgccg acctggccgc cctgggggag cggtggttca ccgcggagta cgcccgcggc
    13261 gggctgttcg acccacgggt gttgaccatg ctgcgcgccc accgcgcggc gggcgacacc
    13321 gtggtgctgc tgtcggggtc gttcgggccg tgcctgaccc cgatcgcccg gtacgcctgc
    13381 gccgacgcgg tggtgtgcac cgagcccgag gtggtctccg gcgttctgtc gggggtcgtg
    13441 gaggttccga tggtcggtcc gaacaaggcg gtcgcggctc gccggttcgc cgaggagcac
    13501 ggggtcgacc tggccgactc cttcgcctac ggggacgaca tctccgacct cccggtgctc
    13561 gacctggtcg gctgcccggt ggtggtcggc ggggacccgg tgctgcgtgc ccacgccgaa
    13621 cgggtcggtt ggcggcggat ccccgcccac acacgagagg aagtcctttg tccgagcaga
    13681 tgacggttgt gcagacggtg gcggcgggtg ggccggaggt actggtgtcc actgtggtgc
    13741 cacggccggt gccggtgccc accgaggtgc tggtgcgggt gcacgcggcg ggggtgaacc
    13801 cggtcgactg gaagatccgg ggcggggtgt tcccgtccgg cgcgctgggc gcgcacccgt
    13861 tcacccaggg ctgggacgtg gccggtgtgg tcgaggccgg gccgcgggtg acccggttcc
    13921 agcccggtga cgaggtgttc gggctgctgt ggttcccgcg ccaggcgggc ggttacggcg
    13981 agtacgtcac cgctccggcg cggcagttcg cgcgcaagcc cgagtcgctg tcgttcaccg
    14041 aggccgccgc gctgccgatg gccgggctga ccgcgtggca gacgttggtg gatgtcgcgg
    14101 ggatcggtga gggcagccgg gtcctgatca cggcggccgc gggtggggtg gggcacctcg
    14161 cgtgccaggt cgcccgctcc cggggtgccg tggtcaccgg gaccgccagc gccgccaagc
    14221 acgacttcct ggcgagcgtc ggcgtccacg aggccgtcga ctacacccgg gtcgaggtcg
    14281 gtaccgcggt gcgcgaccag gacgtcgtcc tcgacctcct cggcggcgac cacaccctcg
    14341 gcctgctcga caccctccgc cccggcggcc tgctggtcct gaccattggc cagatcagcc
    14401 ccgaggtcgc cgccgcggcc aagacccgtg gtgtacgggt gagcccgttc ctcgtcgaac
    14461 cggactcagc aggcttggaa gccttgaccg ccctcgtcga gcgcgacgcc ctgcgggtcc
    14521 acgtcgacca cgtcctcccg ctggcggagg cgggcaaggc ccacgaactc ggcgagacca
    14581 accgcaccac cggaaagatc gtcctctccg tcaccggcac ctgatccccg agcaccgcga
    14641 acccacccgg cgcggtccga cccacctggc cgcggcgcga tcccgtcgcg ccactggtta
    14701 gtcctaccgg ctcctgatcc ccctctaccg caaggagttc tgctgtcgtg tccaccaccg
    14761 tctccccggc gaccagccgg gcaacggcga cgatcacgct gatcgccgtc tgcgtctcgt
    14821 gtggactgct gcccgcgtcg ttgaccggga cctcgatcgc gctgcccgac atcgggtccg
    14881 acctcggcgc cgacctggtg agcgtccagt gggtcgtcaa cgcctacaac ctggctttcg
    14941 cgtcggtgat gctcgccgcg ggggcggtgg ccgacctggt cgggcgcaag cggatgttcg
    15001 gcatcggcct ggtggtgttc ctggcctgca ccgccggggt cgcggcggtg tcggacatcg
    15061 tgctggtcga cgtgctgcgg gcgctggccg gggtcggggc cgcgatggtg ctcaccgccg
    15121 cgtcggccct gttggcgcaa gcgtttgacg gtccggcgcg gctcaaggcg ttcgggctgc
    15181 tcgggtcctc gttcgggctc gggctggcac tgggcccgtc cacctccggc atgctcgtct
    15241 cgctgtgggg ctggcgcgcg gtcttcctcg cccacgccgt catcgccgcc gctgtcctct
    15301 tcgctctccc cgcgctgcgc gagtcccgcg accccgacgc caccggcgtc gactggccgg
    15361 gcaccacgac cttcagcggc gcgctggtcg cgctgaccct cgccctcgtc gaaggcccgc
    15421 aacggggctg gggcgacggc ctggtgctcg cgctgttcgt cgtgttcgcc gtcctgatcg
    15481 ccgcgttcgt cgccgtcgag cgcaggcagg cgcggcccat gttcgacctg ggcctgttcc
    15541 ggcagccgag gttcgtcgcg gtctgcctga tgccggtgct gctggcgttc gggttcgtct
    15601 gcctgctggt gttcctgccg tcgttcttca tcggcatcac cggcatgggc gcccgccagg
    15661 ccggtctcac catgctcctg ctgaccgtgc cggtcctggt gttcccggtc gtggcgggca
    15721 ccctcgccaa gaccatcccg gccagggtgc tgctcggcgt cagcctgctg ctggtggccg
    15781 cgggcgccgc ctggctcacc gtgatcgacc gcgacgcgac cgcgggcacg ctcatcgggc
    15841 cgctgctggt gatcggcacc ggcgtcggca tctccttcgg cctgctcgac ggcgccgcca
    15901 tcggcagcgt cgatccggcc cgcgccggga tggccgcggg catgttcaac acgatgcgcc
    15961 tcaccggtga ggccgtcgcc atcgcgggca tgggctcgct gctggtcagc ctcacccggg
    16021 gcgggctcgg cggcctgacc gactacccgg cggcgggcgc ggtgggggag gtcgcgaaca
    16081 aggtcgccca gggcgaggtc gcctccgtcg ccgcgcgggt gggggagacc cagcgcgcgg
    16141 cgttcgtcga cttcgtctcc ggctcctaca ccagcgcgtt ccacaccgtg ctgtggatcc
    16201 tcgccgcggt ctgcgccctc ggcgccccgg tgatcgccgt gatgctgcgc gaacgcccag
    16261 tcccgaaccc agtggaggcg tgacatgtcc gagaaatccc cggtgctcgt ggtcggcgcg
    16321 ggtcccgtcg ggctcaccgc ggccgtcgaa ctggcccgcc gcggcgtgcc ggtgcggctg
    16381 gtcgaccggg cggccgaacc gagcccgctg accaaggcgc tgatggtctg gccgcgcacc
    16441 ctggaggtgt tccggctgct cggcggctcc gagcacctcg acacctacgg cctgccggtc
    16501 caggcgttcc gctactactc cgagagcagc gaggtctgca agctggcctt cgacgccgag
    16561 accaagccgt cggtggtgac ccagcccgat gtcgaggcgc tgctgcgcaa gtcgctcgcc
    16621 gacgcgggcg gggtgatcga gtgggagacc accgccaccg cgctgcgcca cgacgacacc
    16681 ggcgtcgagg ccaccatcac cgcaccggac ggcacctcgg ccgtcgagcg cttcgcgtac
    16741 ctgatcggcg cggacggggc gggcagcctg gtgcgcaagc agatcgggct ggagttccac
    16801 ggcgccacct accccaacgt gttcatcctc gccgacgtca gcctcgacgg ggacctgcag
    16861 cgcgacgccg tgcactacta ctgctccagc aagggcatca tggtgctgat cccgctctac
    16921 aacgggcggt tccgagtgtt caccgccggt ccgccgggga tgaagccgga ggagctcacc
    16981 gagcaggtgc tccaggacta cgtcgacctg cgtggccccg gcgggctgcg cacgcacgac
    17041 gtgtcgtgga agaccacctt cagcatccac gccaggcaca ccgagcgcct gcgggtcggc
    17101 cgggtcttcc tcgcgggcga cgccgcgcac gtgcacagcc cggcgggcgg gcagggcctc
    17161 aacaccgggg tcaccgacgc gcacaacctg gcctggaagc tcgccctcgt ccaccagggc
    17221 aaggccgcgc cggaactgct ggacacctac gaggtcgagc gccggtcggt ggccgcggcg
    17281 gtggtgcggc aggccgaggt gcagaccaag gcgtggatgc tcaagaagcg ctggcagatc
    17341 cgctcccgcg acctcgccgc gggcctggcc gagaagctgg gcctgttcga ccggtactac
    17401 tcgccgtggc tggcggggct caccaaccac tacccggaga accccgcggt gtccggtccg
    17461 gtggccaagc gcgcgggcgc caagcgcgac cggctgctca gcggctacct ggccccggcg
    17521 gcactgcggg cggtgctgcc gaccgaccgg tacaccctcg tggtgcacgg ctccaccacc
    17581 gccgccgacc agttggcgcg gcgctacccg gacctgctcg ccgtgcgcga ggtgagcgcc
    17641 gagggcgtgc tgcccgacgc cgagggcacc ccggtggccg tcgcctggcg gcccaagcgc
    17701 ccactcgcgg ccctcgtgcg ccccgacggg tacgtcgccg ctgtcgacag aaccccagac
    17761 ctgccaacac tccgggccca cctgaccgcc gtgcgcggct agacccctta cccgtcaagg
    17821 agaccacgat gtccactccc gtcaccaccc gcgacaccgc cgccaccatc ggggagttct
    17881 tcgcccgctt cggcgccggt gaccgccccg gcatgctgga gctgttcgcc gagggcgccg
    17941 agctcgccgt cgcgggcgcc gacaccgtgc cgtggaccgg tgtgcgcacc gaggccgccg
    18001 ccatcgacga gttcctccga atcgccctgg aggacgtcag caccgaggtc ttcaccgtcg
    18061 acaagatcat cgtcgacggt gaagacggtg tcgtgctcgg ctcgctcgca caccggatca
    18121 ccgcgaccga ccgggtgttc gccagcgcgt tcgccctgca catccatgtt gtcgacggcc
    18181 ttatcgccag ttaccggatg ttcgaggaca gccacgccgc cgaggtctcc tggaccaggt
    18241 gagatcgacg ggaaacggtc acacgcggca ttgcgcgccg ggtgtgaccg tttcctgttg
    18301 taggtgctca ggcccaggct gaacaggcta ggcgccgaca gtggtcccgc tgactgctag
    18361 ccggtgggct cctcgacgcg ggcaggtgct ggggtgctcc acatcgccag gagggacagg
    18421 gcctgctccg ccgggctcgc gggttcgggg gagaaggtca ccagccgctg gtcggtttcg
    18481 ccgggtaggt cgaagttctc gaaccgcagc acaagttccc ccaccaccgg gtgccggaac
    18541 cgcttgctgc cgtgcgtgcg ctgcttgacg tcgcggcctg cccacagggt gcggaacagc
    18601 tcgctcttca tggtcagctc gccgatcagg gtggccagcg cctcgtcgtg ggtgtgcctg
    18661 cccgcggcca gccgcagcga ccccgccgtc gcccggcaga cgtcctgcca gtcgacgaag
    18721 cgctgctggc tgtcggcgtc gaggaagccg aacctggcca ggttgcgctg tcggggtgtc
    18781 gcggcggcga agtcgaggaa cagctggcag gacaggtggt tccaggccag cacgtccatc
    18841 cggtggttga tcaccagcgc gggcacccgg tccaggaacg acagcagctg cgccagctcg
    18901 gggcgggccc gctcgggccg cggtccgcgc gacgcgacgg gtcggggccg gaccagctcg
    18961 tcgaggtagc ggcgctccac gtcgtcgagg gccagcgcgc gggccagcga ctccagcacc
    19021 gactccgacg gcctgctcgc ccggccctgc tccaaccgca cgtagtactc gacgctgatg
    19081 cccgccaggg acgcgacctc ctcgcgccgc agcccggcca ccctgcgcct ggcgagcacc
    19141 tcgatgccga cgtcggccgg gtccacgcgg gcgcgccggg acttgaggaa ccggccgagc
    19201 tcgttgcgat cgtccacgcc ccgagtgtgc ccgacggcgc cggtggcgag cgtggtcctg
    19261 tcggtaccag taacggcagg ggcctggctg gggcggtggg gagcggtcag tgttgggccg
    19321 gtcagccccg cccccgtgaa aggttcgcgc gatgtgccac agcaccgaca gcaggccccc
    19381 cgctctcgac aaccccggtg aggtcgccga ggagggtctg ctcgagctga cctccgcgga
    19441 cggcacggcg ttctcggcgt tccgggcgat cccggccgag cccaacggga tcaacatcgt
    19501 gatcctgccc gacatccgcg gcacccaccc gtactaccag gcgctggcca accggttcgc
    19561 gcaggcgggc tacaccaccg cggccatcga ctactacggc cgcaccgcgg gccccggtgt
    19621 gcgcgacgac aagttcgagt ggcagccgct gctgccgcag gtcaaggccg aggaggtcgc
    19681 cgcggacgtg cgcgccgcgg ccacctacct cgagcagcac aacaccggcc cggtgttcac
    19741 cgtcgggttc tgcttcggcg gcggccagtc gtggcggctc tccgccggtg acctgggcgt
    19801 ggcgggcgtg atcggcttct acgggctgcc caagctggtc aacgacgtcg tcgacgacat
    19861 ctccgcgccg ctgctgctcc tgctcgccgg tgaggacgtg gcgacctcgc aggaggagtt
    19921 caaggagttc gcgggcaagc tcgacgccgc gggcaaggac tacgacctgc acgtctacga
    19981 aggcgcgccg cactcgttct tcgacgccag ctacgacgag tggcaggaag cctgcgcgga
    20041 cgcgtgggag cgggtcgtcg ggttcatcca gaagcactcg gcccccgtcg cggtctgatg
    20101 ccgaccgagc gcttccgccg cggcgccgcg cggttggcgg agatgggcgg cgacatcgac
    20161 aacatcgtcg ccccgctggc cgacgtggcc ccggacctgg cccggctggt gggggagttc
    20221 gccttcggtg acctctacac ccgccctggg ctcgacctgc cgcggcggca gctggtgacg
    20281 atcgcggcgc tggtcaccct cggcgacacc gagcggcagt tgcggttcca catcgccgcg
    20341 gcgctcgagg tcggggtgac cccgcagcag gtggtggaga cgatcatcca cctgctcgct
    20401 ttcgccggga acccgcgggt gttcaacgcg atgctggtgg ccaaggcggt gttcgccgag
    20461 cgcggcctgc tgccgctcac cgaccagccg ccggtcgacc cggcaggctg agagccacct
    20521 cccgacgcct cccacggcgt ccggtgggcg aggtgggcga ccccgaaccg ccccctcgcc
    20581 caccgtcacc cggctagcgg cgggtccgcg tgaacatcac cgcggccacc ttgatgtcgc
    20641 gggacttgcg cggcgcgagc acgagcgcgg acttgccgac gcagtccgcg gacaggtaca
    20701 gcaccgcttg ccggtcggtc cggttctcga cccggcggat cgtggtcccc agcgggtagc
    20761 agacgttgtc gctcgggttc acgatccccg cgccgccgtc gtcgtcgtag aaggtgaagg
    20821 tgccccgcgc ggccgcggcc ggggtcaccg cctgggtcgc gagcacgcag gcgaagagca
    20881 cgccgagcgc gatccgggtc gctgatctca tggtttcctc tcgtcgggaa ctgacaccag
    20941 ggcggcgggg tggatcgcgc acgggggagc gggcggggtc gggggtctcg cag
//
