LOCUS       NZ_RCDD01000002        34798 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Actinokineospora cianjurensis strain DSM 45657 Ga0180969_102, whole
            genome shotgun sequence.
ACCESSION   NZ_RCDD01000002
VERSION     NZ_RCDD01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora cianjurensis
  ORGANISM  Actinokineospora cianjurensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 1225445)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1225445)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 102.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003663795.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:08:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,669
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,552
            CDSs (with protein)               :: 6,552
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3, 1 (5S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 10 of 54
            Pseudo Genes (incomplete)         :: 50 of 54
            Pseudo Genes (internal stop)      :: 2 of 54
            Pseudo Genes (multiple problems)  :: 7 of 54
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1141317
            Orig. end                         :: 1176115
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RCDD01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..34798
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="6"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..34798
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..34798
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:24798](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..24798
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(1360..2289)
                     /locus_tag="CLV68_RS19595"
                     /old_locus_tag="CLV68_3954"
     CDS             complement(1360..2289)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007499481.1"
                     /locus_tag="CLV68_RS19595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3954"
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="WP_121392236.1"
                     /transl_table=11
                     /translation="MATLLQQLINGLVLGGLIALIALGYTMVYGIIQLINFAHGEVFMV
                     GGFASLATYRYFLPPSWRSDWWLALPLMAIGGAVVAVVLAVVMERFAYRPLRNAPRLAP
                     LITALGVSVILKEVVRLGYPGATAPVPFPRAFVDHQFRFEFFDGTVNIGSTAILMIVVS
                     IVGAIVLQTYITKSRMGRAMRATAQDPDTARLMGVNPNRTIVLTFTIGGALAGIAGVLY
                     GIHITNVDTEVGFLYGIFAFTAAVLGGVGSIKGAVIGGFAIGLIKTLSGQYFPGGTQYD
                     LVWIFVLLIVVLVFRPQGLFGEPERVRA"
     gene            complement(2365..3597)
                     /locus_tag="CLV68_RS19600"
                     /old_locus_tag="CLV68_3955"
     CDS             complement(2365..3597)
                     /GO_function="GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683651.1"
                     /locus_tag="CLV68_RS19600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3955"
                     /product="branched-chain amino acid ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_121392237.1"
                     /transl_table=11
                     /translation="MRNQTVKAAVLVAGALLLAACGTNKTESGSGGGNNQSCDQSKGTL
                     VIGVIAPQSGGLSALGLGIRNSAQLAAAQANEKCATPGYKLEVQTEDDQATAQVGAQAA
                     TRLSSNANVVGVVGTLNSSVAQSVQPILKGKNIVQVSPANTNPSLTRGAEYGTAPKRQF
                     ENYFRVCATDDLQGPFAAKYLVGKAGKKSIAIITDGKTYGEGLAAEFKKQAEKDGAKIV
                     ATAKVGEKDTDFSGVIGTISGSKPDAVYYGGEYPQAGPLSKQLKDAGLNIPVMGGDGIY
                     DGKYIELGGKEGDLATSVGAPTDTLDTAKAFVSAYKAKAYKDDFSAYGAFSYDATNAII
                     GALSKTLTGGGEWSEAKRTDVIKNVQSYSAEGATGEVKFDEYGDSTNKLLTVYKVSGGK
                     WVADETGTFGG"
     misc_feature    3805..3819
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.6"
                     /tool="antismash"
     gene            3863..5734
                     /locus_tag="CLV68_RS33435"
                     /old_locus_tag="CLV68_3956"
     CDS             3863..5734
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS33435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_3956"
                     /product="fibronectin type III domain-containing protein"
                     /protein_id="WP_170224450.1"
                     /transl_table=11
                     /translation="MRLRNRVLAWGSAGLAIGAAVLLLRAPVEPPKPGPAPMPSPERVS
                     RFAADDVVLPEVGAPPDTPRDLRVRAAPGLLVVSWAEAARATGYEVRWSGADQSPGTRL
                     VATRDTQLDGLVDGREYRIEVRAVDAFGQVSAPAPAKGNPGPGDTSWRRGLTGLLDDFP
                     DDSSLRADTVGSLWHLSGYRGCVDLGARAVGEVGLPIDLGCGADEAVLRARAPMVLDES
                     TPDGDLGRVAVVTDAAGPGGRLTLDLVPGPADRVGSVDGVGSLPPGTVRAVVDDTGARV
                     GERGEFVEAPGPRGAGALHLYEVRVTTTGVTLSQDGRVIASSPVVPSWRSAWLLVGVRG
                     PEGRRARVHVASAGFTGVASPVPQVVETPVNLATRQVLDPSATAPSAGILRRPLATALS
                     ARLVVTMVVSPGMDVGASWIQLGTAVLPARPVAPPPPEPGSVVTVIADVPQSLLGGNGS
                     DSLSPLVVRAPGAGQGALVQESYLELVPGPIASVRTTTQPARTNRQRPTVNALPTATLT
                     LGDSTGRPLTTPSLPAQGRLVLTVTLNGAAAQWDTGSLEGVQGFQLWVDGRMTASLPTS
                     SHTGAPAGRYAIPVALTGRAVGEHAVEVRVIGTNGTRGSTLTQFTTT"
     gene            complement(5736..6335)
                     /locus_tag="CLV68_RS19610"
                     /old_locus_tag="CLV68_3957"
     CDS             complement(5736..6335)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005157321.1"
                     /locus_tag="CLV68_RS19610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3957"
                     /product="response regulator"
                     /protein_id="WP_177215666.1"
                     /transl_table=11
                     /translation="MSDLAAEARPAPRRVLVAEDEALIRLDLVEMLREEGYEVAGEAGD
                     GEEAVRLAGELRPDLVILDVKMPRMDGIEAATMIAGERIAPVVMLTAFSQRELVERARD
                     AGAMAYLVKPFAKHDLVPAIELAVSRFAEVQALENEVAGLTERLETRKVIERAKGLLMN
                     KQGLSEPEAFRWIQRTAMDRRTTMKAVAEAVVDNIT"
     tRNA            6480..6553
                     /anticodon=(pos:1147831..1147833,aa:Leu,seq:caa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CLV68_RS19615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="CLV68_3958"
                     /product="tRNA-Leu"
     gene            6480..6553
                     /locus_tag="CLV68_RS19615"
                     /old_locus_tag="CLV68_3958"
     misc_feature    complement(6617..6631)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.0"
                     /tool="antismash"
     aSDomain        8107..8331
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CLV68_RS33440_Thiopeptide_F_RRE.1"
                     /evalue="1.70E-15"
                     /identifier="RREFam004.1"
                     /label="CLV68_RS33440"
                     /locus_tag="CLV68_RS33440"
                     /protein_end="75"
                     /protein_start="0"
                     /score="47.8"
                     /tool="antismash"
                     /translation="MVLVLRPDAYVAETPNGAFVLTNSGSYTFTGHTIFALLTTIKPYI
                     NGEYTLDQLAARINKRAREVAVKLLTGMLD"
     gene            8107..10011
                     /locus_tag="CLV68_RS33440"
                     /old_locus_tag="CLV68_3959"
     CDS             8107..10011
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS33440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_3959"
                     /product="hypothetical protein"
                     /protein_id="WP_147460070.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 6.3e-14,
                     bitscore: 47.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLVLRPDAYVAETPNGAFVLTNSGSYTFTGHTIFALLTTIKPYI
                     NGEYTLDQLAARINKRAREVAVKLLTGMLDLDIVRDIERLKIQSSQPEVRFIEYFQDDA
                     ARTYSEYCSMSALIIGRSPLAQAVEAACRLSGLRTRSVDQTEDREAAPMDSAAMDDVIF
                     VVGGEPDYHSKVEEELSCDHDGVLVHATTIGEAWFCCIGKADEAVWASVTQRLAARRAP
                     AQAPRASPEGRPDDHAVRVLAAQLVHNAFRLITTPSAARGGVNRVDQATLASEPISYLR
                     HPYTLPAQPRTATQFAHRIATLAASPELDEEAFSRHAVSCTGEWTGVFGLPTEREFAQT
                     PLCVCQIEVSATTGGSTSHVTGAGLDFAAARYQASLRAFASYGSTIFDPRQMLDINEQP
                     LVQRAEGLDLITEDLQSGRLAGFVWAYNLATSRPMLLDAVRAFPNTDEGSHLGSAAAAY
                     SWKAAISAALISQCHRMTLLEQTGSAPELDITNIPPNSQLEHYRVILSKIGPVVVRDIT
                     GSLEVPTVICLLKGVHLGSGSGLSYLDAVTAAMEEALLSYQASANQQPEYAPPTAPTAP
                     QASRSRLPFPVDRPRTVDSVIQTLHRSGHTPLVVPLDHDPEVAAIMPYLVRVVLSDGR"
     misc_feature    8506..8508
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9388..9390
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..11956
                     /locus_tag="CLV68_RS19620"
                     /old_locus_tag="CLV68_3960"
     CDS             10001..11956
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="CLV68_RS19620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3960"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_121392239.1"
                     /sec_met_domain="YcaO (E-value: 9.6e-78, bitscore: 258.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 3.1e-107, bitscore:
                     354.6, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAEHATPIAILGNGLLANALIKRPGVHQATSVAEVDAGCRMIVV
                     ATDGWDDSAYHSVRAVAARFGRPWLPVRTELGRIVIGPVEQPGVPGCGICVERRRAQIS
                     ATNDGVEAVHRAHGTVLATRSSSWLTTLAADVATSLVLREADRLTSKQDEPRAACGYLD
                     IDLASLVVRRHEFLPDPLCPNCGYLPDDSPVLAHIRRTRQPKPAPDHYRIRSVADELPA
                     LMGLYVDSECGLIRSVSKDQDGGVVIAAAPVGLRIEAREFGFGRSRNYRDSQVTAILEA
                     LERYGGVRPGGKRTSVRASYAEVRDNAVNPRTLGLYPADRYLAPGFRFQPFSETQPYRW
                     VWGYSFARQDSILVPETYAYYGVSRLPEADIPFVFETSNGCALGSCAAEAILHGVLEIA
                     ERDAFLMAWYARLPVPRIDLDSAVDKAIPLTANALRAETGYEVMAFDTTTEQGIPCVWV
                     MAVDPVGDGERPKAVCAAGAHLDPEHAIENALNELGPIVADLIRRHRFDRERARSLATD
                     PGLVVEMADHSLLYANPEVFSRLDFLASSGPSIPISAMAQPTAFRNDDLEDDLDELVRR
                     YLNTGLDVIVVDQTTPEHRAGDFSCVKVIIPGTLPMTFGHDLRRVDGLPRLYDIPSRLG
                     RRLRRQDVNPHPHPFP"
     gene            11964..12299
                     /locus_tag="CLV68_RS19625"
                     /old_locus_tag="CLV68_3961"
     CDS             11964..12299
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: thio_amide"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS19625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_3961"
                     /product="hypothetical protein"
                     /protein_id="WP_121392240.1"
                     /sec_met_domain="thio_amide (E-value: 6.2e-29, bitscore:
                     95.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYLQIVAWDLSRSQATVEGLRGYLKDYAVDAYSTLDGMAMKVWFG
                     NPEKQVWGAVYLWDSLEHAHGITTVTRVVDLIGYPPTSVSVFPVEAISRGRSRHDVIVG
                     LGLALEN"
     gene            12322..14241
                     /locus_tag="CLV68_RS19630"
                     /old_locus_tag="CLV68_3962"
     CDS             12322..14241
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thiopeptide_F_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Heterocycloanthracin_C_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.4"
                     /locus_tag="CLV68_RS19630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3962"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_121392241.1"
                     /sec_met_domain="Thiopeptide_F_RRE (E-value: 5.3e-19,
                     bitscore: 64.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Heterocycloanthracin_C_RRE (E-value:
                     1.1e-07, bitscore: 27.6, seeds: 5, tool:
                     rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 6.1e-08, bitscore: 28.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPGADNAIAGEARPRLRHDVVLADTGDGVLIRTPDGHLVVKGPA
                     AYPFAARLAPHLTGAWTVAELCSSLPDDKSRLVAAFVETLLEHGFARDTRSPRSGPRNT
                     SYATQIDLIEHYRDDAEEAFLAFQNATIQVAGAGAVDRATANSLMRNGARNVTVITTPV
                     EPLPADAVCGSAIPLETAPAPLVLPVLTHAGKALLGPATRPGGESCWNCLLLTLEVSES
                     DTPLRQPQADYVGNALGTELFRKLTGIPTPTDGGVVVIDLDTLECTHERVLRHPSCAFC
                     TRAEPVPVVPARAVQEPAAQFRAPSRLMLRALVGELDRSTSPTTGLLTGFHDTSVTQSP
                     LKVGQVRTRCGRTITAFDPHHLPVARQRAVHAALLVHASRFTSGGVAEPAAPVPPNELL
                     LWSGQTSTRFSLWLPMTSLLSRTSHFVPAAAVHPVTVHNNSGSFVRTGAGDGIGPTTAE
                     ATLRGLLTAFAHHSLGGTHEEIHLRQADLDPEIDFLLRTLAVLGVTATLTDLAPGMAHR
                     VVRARSSDSGLTSIGAALSTRAATVSALRDLLGRIQLAREGVPFDAGNPLLSHPTCSIY
                     AACALSADDDPAGLYENLIARGLDALAVVTTPSDVAQLGLVTVRVLLRRLDRVHRPRPV
                     RRKT"
     aSDomain        12355..12594
                     /aSDomain="Thiopeptide_F_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing F protein in a thiopeptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CLV68_RS19630_Thiopeptide_F_RRE.1"
                     /evalue="1.40E-20"
                     /identifier="RREFam004.1"
                     /label="CLV68_RS19630"
                     /locus_tag="CLV68_RS19630"
                     /protein_end="91"
                     /protein_start="11"
                     /score="64.0"
                     /tool="antismash"
                     /translation="EARPRLRHDVVLADTGDGVLIRTPDGHLVVKGPAAYPFAARLAPH
                     LTGAWTVAELCSSLPDDKSRLVAAFVETLLEHGFA"
     aSDomain        12358..12612
                     /aSDomain="Heterocycloanthracin_C_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing C protein in a
                     heterocycloanthracin LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CLV68_RS19630_Heterocycloanthracin_C_
                     RRE.1"
                     /evalue="3.00E-09"
                     /identifier="RREFam011.1"
                     /label="CLV68_RS19630"
                     /locus_tag="CLV68_RS19630"
                     /protein_end="97"
                     /protein_start="12"
                     /score="27.6"
                     /tool="antismash"
                     /translation="ARPRLRHDVVLADTGDGVLIRTPDGHLVVKGPAAYPFAARLAPHL
                     TGAWTVAELCSSLPDDKSRLVAAFVETLLEHGFARDTRSP"
     misc_feature    13243..13245
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    14197..14199
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14619..15431
                     /locus_tag="CLV68_RS19635"
                     /old_locus_tag="CLV68_3963"
     CDS             14619..15431
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="CLV68_RS19635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3963"
                     /product="cytochrome P450"
                     /protein_id="WP_342772786.1"
                     /sec_met_domain="p450 (E-value: 5.4e-30, bitscore: 100.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAHGPPTDLVHAFALPIPSILICELLGVPYAQRERFQRDTAVLF
                     DLDSQPDRVNAAWSSLGGLLSALAREKRLRPTDDVISELVGGGDLTEQEVVMVAIVLLA
                     AGHETSATMIAHGIFALLRHPEQLARIRADPPLVDKAVEELLRYLSIFHIGPARSALAD
                     VLVAGQLVKRGDTVAISLPAANRDPSEFTNPDELDVGRDHNRHLAFGHGIHQCLGQQLA
                     RVELRVGLGRLLRRFPDLRLAVPAEDVPVRGNIAVYGVQSLPVTWGQR"
     gene            15428..17266
                     /locus_tag="CLV68_RS19640"
                     /old_locus_tag="CLV68_3964"
     CDS             15428..17266
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="CLV68_RS19640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3964"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_121392243.1"
                     /sec_met_domain="YcaO (E-value: 1.2e-77, bitscore: 257.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 5.6e-92, bitscore:
                     304.4, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQDAAAITDYFRDRLVRSEVIAPAIGVLGSPRPSALDEVVPIHL
                     DEGLVVLGPIRAPGGTGPCAECLRLRWEQRAGADQPRESVRIARSPHLTPFMMEAVLQL
                     WLCLRARRPKPGTGTGTAPLYRVDLPSGRVERMALLADPSCSVCGPPAHDPPIDFRLVT
                     REKHAVDTFRASALADVDLPVSALVNSVCGLIGAKVELGLPSPTTAPAFGSFTTQARGG
                     VHDILWMGQTNRFDDSRTAALLEGLERYAGVRHRASSSEIIERLVDVGEPAVDPRDCGL
                     YADGFYHDSGAYKPFDPERPISWVDGHSVRDGRTVLVPRQIAYFGEAATGQVFADGSSN
                     GCAIGANLEEAALHGLLELVERDSALLAWYGGGPLPEIDPASCDDLQIRLTVEQVRLAG
                     FDVRLFDARSDLAIPVVIAVAIRLDGGPGARTFASGADLDPVGAIRSALFEVASYAPDL
                     AGRVLARLPAVERMAADFGNVVDLMDHSLVHGLPAMATHSDFLLAPNRKLPVRELYADV
                     DPRGLDLLDDLDYCIGQVARAGHDVVVVDQTRPEHRAIGLRAVRVVAPGLLPIDFGWRK
                     QRALNMPRLRNALQRTNLARDAPADGEPHRVPHPYG"
     misc_feature    15971..15973
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17290..18339
                     /locus_tag="CLV68_RS19645"
                     /old_locus_tag="CLV68_3965"
     CDS             17290..18339
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013209.4"
                     /locus_tag="CLV68_RS19645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3965"
                     /product="ArsR family transcriptional regulator"
                     /protein_id="WP_121392244.1"
                     /transl_table=11
                     /translation="MLRLLLTFDDALRIRMAPSADPLWETRLSLQALRRPVCGIHIDAW
                     RRGINTTLSRDQLVRSALRFLTPLVPVEGYVPDFLTPTAGNRGVRAGIDAVLETPPSRV
                     KSELAMLVRSGPVPRHVHELASGDLGTMKRLGWALGTYHDAVIAPHWGRVQALVDADRA
                     QRARTVADQGAEQVLAGLDGVRWHPPRLEVDSPVDRVLDLGGSGLQLVPSLFCQGKPVM
                     PVDEGLPRVLVYPIDLGTGWSWHEDKLDADQRDVRALLGSTRATILEHLVARDRFTGEL
                     ARIVAMTPATVSKHTAVLRHAGLIISTQSGRHVTHRLTRLGAALLNRSSRISSPEGKRR
                     SVPSGDVQK"
     gene            18381..18560
                     /locus_tag="CLV68_RS19650"
                     /old_locus_tag="CLV68_3966"
     CDS             18381..18560
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033399.2"
                     /locus_tag="CLV68_RS19650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3966"
                     /product="thiomuracin/GE37468 family thiazolyl RiPP
                     peptide"
                     /protein_id="WP_121392245.1"
                     /transl_table=11
                     /translation="MSVPNLDFDLENLPMDVFDLGQNGLTIESLTSGHGMVENGASVPC
                     PSVCSTSTISCSSS"
     gene            18672..21320
                     /locus_tag="CLV68_RS19655"
                     /old_locus_tag="CLV68_3967"
     CDS             18672..21320
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="CLV68_RS19655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3967"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_170224451.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-55, bitscore:
                     184.6, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANPLIVRRGGLPLNSLDRLRFEQSFAAATEIVRSRDRLVAEGTT
                     LADALYSVIGELADAAGKPGLVGLRRALHSMRPPAAKEWNDTTCSALPSEIAARVSAWV
                     TDLRRHERERAGLADVLAAERCEKQEVLRYESAQHGFRRALSQASATLYAELDKWLADP
                     QHRPREQVMVRLVKYMSRAAMKTSPYSTFTVTGAGTWTEAGAAAHFTNASVAGVVELDG
                     FLLRQLSGLLCEDPRLAPFLTVRVNPSATVSDNRVTFTGPSPREPIVTMPVNAAVRACL
                     EILSEHPPTSFTELHERLSDGADPAVVRLFLGALLDAGLLERQLPFTDQELDPLEVLCD
                     WTTTVGGDDFTHIVSLLQRVRRALRASVPVPDVEAQVARQNELKQAVIDLGTGLGLPLD
                     HTQRQGSFMFRENAVFTSPVVECSTAHWQPALDDLDVVRRWMAPFDLALPLRIVLGTFV
                     GERFGQGARVPLLAVHRAVQESVAAGPSSSMSDAEQEIVRFLSSSPLDQMTGDAHSPVA
                     RLRQLNRVRAQARGALLSGTRAPTATQVDPVLLSEMIATWPLWIAAPRSLACYVQLLPG
                     EEMGLVLNSAHTGHGRGRSRSLQLIKDAGGTTPPLAIEHNAVGTPVDAELGGLAVSALN
                     RRVASLPYEIDYPLAVSGRPAEERITLGELLVVHDPESQLVRLFSPALGRDVRSLHVGM
                     MSDFLLPPVARLLTQAFGATHYVHPSIPLVATHSDLTTPAGIVHHPRITVGRVVVQRER
                     WVVPITEVPVREKGESADSHLLRLVDWLHTTSIPAQCFVRVWTGLSTSHELGPNGWENW
                     VFDKSRKPVYVDFANWYLVMAFDKMLRDSAQAVVFEEVLPSHAGASATGQDDRRATEFL
                     VELTGQVDHDA"
     gene            21313..22290
                     /locus_tag="CLV68_RS19660"
                     /old_locus_tag="CLV68_3968"
     CDS             21313..22290
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF025394.4"
                     /locus_tag="CLV68_RS19660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3968"
                     /product="lantibiotic dehydratase C-terminal
                     domain-containing protein"
                     /protein_id="WP_121392247.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8e-51, bitscore:
                     169.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDTGYVSAHAFYQGDLDTLIVQGLPGILDDLRGRRLVDDFFFLR
                     YWDGGTHLRLRVRPGPDTERRLVEDLITSRFSEFFARSPANHTMSQEEYGALAASLAEW
                     EGVPSHVEQLYPNNSVALIPYQPEHERYGRGASLAAAERHFGDSSRIALAMLARGLSPD
                     ERTTAAASMIMLAWFSVEPDPGRLRRAITVSRYTDTLLGKEKDLVQRGHGQVVRLARHM
                     FALSAHAPGLRNDGLLVRWARSAATLVDELAAEVASGAFSPPSRGWEGSEAASTIEPRL
                     RVLPVIDICAHLLCNRLGVSIAEEAVIRVRLLNALETLSMEDVT"
     misc_feature    22153..22155
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            22287..23372
                     /locus_tag="CLV68_RS19665"
                     /old_locus_tag="CLV68_3969"
     CDS             22287..23372
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF045556.1"
                     /locus_tag="CLV68_RS19665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3969"
                     /product="thiopeptide maturation pyridine synthase"
                     /protein_id="WP_170224452.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.6e-64, bitscore:
                     214.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQWHAVHIHYHDDPDPLIIGGIRPLFQRLAGVVTGMYYTRHWRL
                     GPHLRLRFRCTERAFARAVRPAVEDVIGGFLAARPSTSELDPDSFLTAHQRLADLEQEP
                     GALVPWHPDNSFHVADQTPRVEVHGGLAMADLLDDFYSDTTELALQTTQRVPRGSARLA
                     LGFDLMVAVAHALSGVGITGGCLSYRSHAEAFLCTFPEGTGLRPAWDDHYRLHSSALLA
                     RLRNVTAGLGNGGAAESPITAWVEVLNDYQGRATRLMDQGLFAMPQGDARSELDLARRS
                     PLHQAGFANPRWLEVRESAGFLLYRLMINYTYLHLSRLGVAPVERFQLCHLAASAVEDL
                     HGVSALSMMTYGVNAPLPETR"
     misc_feature    22692..22694
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            23377..24798
                     /locus_tag="CLV68_RS19670"
                     /old_locus_tag="CLV68_3970"
     CDS             23377..24798
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="CLV68_RS19670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3970"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_121392248.1"
                     /sec_met_domain="PF00881 (E-value: 1.9e-13, bitscore: 46.8,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSSPVNVATTSEYTEMFQLRPGVFSARSATEEVHLVRWQLWQHD
                     ESFGKLSEDQARALERLAAGPCSAMDLSQGVDEPAPLVRALRAGGWLTTIVYEGDRALY
                     TVLPLDPPPAETVTSECELVLSRFAVMRREGDGLVVESPVAWAQMHIHDPQLAAILMGA
                     DGGSASGVRTRFEKDLRLSGLLVPAGSEETNPASSQWRSHELWFHQRSRRGNGGYFGAG
                     YGRTQWAHGAMDLLPARRTSFSAPAIELYRPELAALRLEDTTLTTAVEERRSVRVHDDT
                     SPMTADQLGEFLFRCARVRGTFVADGIEYASRPLPSGGGVAELELYPVVRQVEGLAPGM
                     YHYDSHAHQLRMARGPGHEVTRLLRTAAHTAVVQTRPQVLIVISARFGRLMRTYEEMPY
                     SIVLKHVGVLYQTMYLVATAMGLAPCGLGGGDAAAFTAAIGADPLMEASVGEFMLGSRP
                     PGDEYRDTSAHEPAE"
     gene            25207..25457
                     /locus_tag="CLV68_RS35695"
                     /pseudo=""
     CDS             25207..25457
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013756.4"
                     /locus_tag="CLV68_RS35695"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="flavin reductase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGLVASSFTSVSFEPPLVSFSIRPRGLAVR"
     gene            complement(25447..26046)
                     /locus_tag="CLV68_RS19680"
                     /old_locus_tag="CLV68_3973"
     CDS             complement(25447..26046)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018683757.1"
                     /locus_tag="CLV68_RS19680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3973"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_121392249.1"
                     /transl_table=11
                     /translation="MRARDVMTSPVVTVTPTTTVKHAAELLDSHGFTTLPVVSADGGLL
                     GVVTEADIVRDRFPRDPRFRHLHPAAVPPPNTVAGIMTTPAPRAAAGTDIADLVTTMRD
                     NALRALPIVTGDRLVGITTRADLLHLLTRDDRALATALRHRLTLYGDPARWTIDVTDGT
                     ATITDTHDDPTDHHVAEVLATSIPGITSARVTRVTG"
     misc_feature    26232..26246
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.57"
                     /tool="antismash"
     gene            26240..27181
                     /locus_tag="CLV68_RS19685"
                     /old_locus_tag="CLV68_3974"
     CDS             26240..27181
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS19685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_3974"
                     /product="nitroreductase"
                     /protein_id="WP_121392250.1"
                     /transl_table=11
                     /translation="MSTTVSTVHAAISAAVRAPSPFNTQPWLFAAHPDRVDLWLDRSRV
                     MTVTDPDAHEARVGCGAALHTLRLALAVSGHRTEVHVLPDRTRPDLLATVLLDGKYRPT
                     PHERALSEAVWRRHTNRRPFLDRPVPSPAKTALMRAATVEGAQLHLMDQPAEVGAVADL
                     VRRADHVLSQDSAHVDEVHAWIGRQGRSDGVPVAASGRPSTPDTLIVLRELGSPAPAVP
                     FERLPLLGVLTTVGDTHSDHLAAGQALQAVLLQACAAGLAVSPLSQPIEVPATRDALSA
                     HVGAAAHLVLRIGYGHSGTTTPRRPVSEVVLD"
     gene            27284..29122
                     /locus_tag="CLV68_RS19690"
                     /old_locus_tag="CLV68_3975"
     CDS             27284..29122
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680496.1"
                     /locus_tag="CLV68_RS19690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3975"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_246009982.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-39, bitscore:
                     131.8, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKALSLSMAVVVGLVSVTPSAAAEASSGYVVVLKDGRAPAAEYA
                     VRQTFRHAVNGFSTDLTPRQAQALAADPAVAYVQPNRRVRADTTQTYPPSWGLDRIDQR
                     DGDLDDAYTYSTTASNVTAYVIDTGVYTANTDFGGRATWGTNTSGDGKDADCHGHGTHV
                     AGTIGGARHGVAKGINVVAVKVLDCNGNGTTETVAAGIDWVIAHHTSGPAVANLSLGGE
                     ADPVLDAAIRRLIADGITTTVSAGNSGADACQQSPARTAEAITVGSTSEGDDRSSFSNT
                     GTCVDLFAPGESITSAWKSYPDSTNTLSGTSMAAPHVAGAAALLLAVDPATTPAQVAAH
                     LVLDATPGKITDVGPGSPNRLVVVGTGSRPGYPIVANPGYRAQRTGTPMTIQVAASGGT
                     APYTWSAAGLPTGTSIGASTGLISGTPTQTLVNSPVTVSAKDSANRTTTVRFLVTVVPP
                     GWTCPSGGQKLANPGFESGDTVWWTSGYYVDRWTGVNAPRTGSWAVKIPTTTSMGNHAV
                     PEDVRIPQECAWSTLTFWVKVTHQGAKDDWDKLHVRIDGKTLATVLGKTAPAGYQQYTV
                     DLSGHAGKTVRIWFTTWGDTANITDFVLDDVAVTLR"
     misc_feature    27318..27333
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            29144..29788
                     /gene="lexA"
                     /locus_tag="CLV68_RS19695"
                     /old_locus_tag="CLV68_3976"
     CDS             29144..29788
                     /EC_number="3.4.21.88"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006282 - regulation of DNA repair
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="lexA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018681600.1"
                     /locus_tag="CLV68_RS19695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3976"
                     /product="transcriptional repressor LexA"
                     /protein_id="WP_121392251.1"
                     /transl_table=11
                     /translation="MTTDLFGGLDASTLPERQQRILLAIQDWVVRHGYSPSTREIGDAV
                     GLRSASAVSRHLASLEDKGFLRRGASVSRPIDVRDFLGTQESVPADSVGVPIVGDIAAG
                     APITADQHVDDVLTLSRELTGRGTVFALRVRGDSMVDAAICDGDIVVVRQGPEAHSGQV
                     VAAMIDEEATVKVYRHRNGHVYLEPRNDAYDVIDGDNAVILGTVVSVLRTI"
     gene            complement(30059..32656)
                     /locus_tag="CLV68_RS19700"
                     /old_locus_tag="CLV68_3977"
     CDS             complement(30059..32656)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="CLV68_RS19700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3977"
                     /product="AAA family ATPase"
                     /protein_id="WP_121392252.1"
                     /transl_table=11
                     /translation="MTGVLVQRRAELAAAVGAVRVAGAPLHVVGDTGHGKSRFVDELLA
                     DPAVRDRRVVRGVCQPPSVGTFAYGPVVDGLRVAVAEIGAVRLNPVVGALRSVLPEVAE
                     LLPPVPDRVDEAAGRHLVFRAVRELLVALAPVVLVVEDAHWADEDTRALLRFLISTVAN
                     RVAVVLTYRPGCGSLGVPGTRVDLGPFTREDLDPLVPDADALLAHTGGVPYLVAAGFSV
                     PAAAYDDVATRLEGACADTRAVVVAAAVVDVPVSTQVLARIGGVSGGRDAVVAALRTGV
                     LVEHAPDAFRVANGVFRRVVYDELTGPERVESHRRALRALRGMPGVAPRVLAEHARLAG
                     RLGEWVEQVEAVITATQDSTAPARDSAAGASVVVEAIEPLLAEPALSAADLCRLAVRYA
                     GVVGVGGLPVLTKLVGDARLTESARAEVRLGRGLLLVRAGVYEGVGEVRRAVAGLRPEV
                     AARGMVVLAAPTLGSRPLAENLEWMDRSERVLARYPEGPGRTTLLAAVATNRLHTADPV
                     AWDMLAMVPAHADTADHRAIAEAACWIGHRDLARAHLRRAPGPAALVLDFHSGQWTGLA
                     ERAAASRSAEGALVLAWLALATGDWAGAERNLAAISADAIVPVLLAAHATAIRMWLHRD
                     RSEEVEDAVKLGLGLLRDKGNWAWAGEVVPAAVAALCRLGRLDDARRLVAELLRCTASM
                     NLPSIVADECRGLVAEADGDVETAAAHYTLARQGSPRYTATRHAESTARCRLRTHRTAA
                     TADLLTVVDTLEHLGATLDANRCRHLLRDNGSIPHLRRGRRSYGDQLSPRERDVVRLLA
                     QHRSNQDIADVLFLSRRTVEQHVANVLRKLHLDSRHEVARTFPDTLTVSRPPA"
     gene            32875..34449
                     /locus_tag="CLV68_RS19705"
                     /old_locus_tag="CLV68_3978"
     CDS             32875..34449
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005151567.1"
                     /locus_tag="CLV68_RS19705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_3978"
                     /product="S8 family peptidase"
                     /protein_id="WP_121392253.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 6e-35, bitscore:
                     116.9, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNYRYSMRSLAVAGVVAGAALVAAVAPAIAAPAEGTIRSAGVPGS
                     VAGSYIVVLKDTAGAQAVNSVSADLTSKYGGQRKLTYSAALSGFSVSMSEQQARRLAAD
                     PKVAYVEQDGTAHGFGEQPNPTWGLDRIDQRSLPADNKYAYPNDGEGATVYVVDTGVYR
                     GHSDFGGRVTSGRDFIDNDADASDCHGHGTHVAGTVGSATYGVAKKVKIVAVRVLDCQS
                     SGQWSQIIGGFDWVAANAGANSVMTASLGGSSNSSVDDAVAKVVQKGITSTIAAGNNNG
                     DACQTSPARTPSAITVGASDNADKRSLWTNGQGSNYGTCVDLFAPGTNILSTLQNGSSG
                     TMSGTSMATPHVAGAAALYLTAKPGSTPSQVSSALVAAATPDKISDPKGSPNKLLYVKE
                     LGGGTPPNPGTCAPQTSSGAVAIPDASSADSPVTMANCTGTASASTTVKVDIDHTFTAD
                     LAVDLVGPSGAVFSLRPSGGLGDANGIHTTYTVNASGEQKNGTWKLRVTDVYRFDTGSI
                     TSWTLTP"
ORIGIN
        1 agttcttgag gttcgcgaac accaccatga ccagagccac cagcacgatg atcagcacgt
       61 agtagagaac gccggaaggc agctctaccg agccgatggt cagcggcttc tcgaaggact
      121 gaccgaacca gttgatcggc ggcacgttgg ggatggcgtt cgcgccaccg gtcaggtcgc
      181 cgatgttgtt ctgcgcggcc ttcttgaaga tctcaccgaa ggcaagggtc acgatggcca
      241 ggtagtcacc gcgcacccgt agcgtcgggg atccgacgac ggcgccgaag atgcccgcca
      301 cgaccgcggc gatgatcgcc gccaccacga acggcagctc gatgtcgaac gcggcggccg
      361 cggcacctga gaagttcgcc gcgacgaacg cgccgatgcc caggaacgcc acgtacccca
      421 ggtcgagcag accggcgagg ccgacgacga tgttgaggcc gatggcggtc gcggcgtaca
      481 cgccgatgtt ggccgccgtc gtcatccagt agtcggtgcc cgcctcggtg aacggcaacc
      541 cgagcgccac cagcagcagc accacgacgc tgaaccactt gtgctggtcc gacagcgcgg
      601 agatccaggt ggtgaggccg atcgcctgta gcgtgccgag cacaccggcc aggaaggcga
      661 gcagggacag gaagatcggg ccagcgtacg ggttgccgac accgccctga ccaccggcgt
      721 tgagcatcat cgcgacgacg agcaggagca cgacgaagga gatgaccagc accgcgtagg
      781 cgacgagcct ggggaccgcg gccttccagt gcggtaccgg ttccaacacg ccaccggtct
      841 tggcggcgaa cagcagcagc aggcccgcga cgagggtcgc gatgccgccg aaggcgaagg
      901 tctcgccgtc ggaggtgatc gcgccgagac cgccgccgtc gatcaccggg aagaggatgt
      961 tcaccagcgc gatgccgatc gcgccgaggc cgagcgcgcg cagcaccctg cgcctgggca
     1021 gcgggaggaa cagcacgacg atggcgagga cgccgagcac cagcgtgtgc aggcggaacc
     1081 cgctcagcgc gaagggggcg tcgaagaact gcagggtcgc cttgtcgggg tagggaccgt
     1141 cgttgaggcg gaaggtcacc cacggcagca gggcaccgat gacggcgatg acaccgcctg
     1201 ccaggcccag tgggcggacc agcgccgggc gcggggccag gaacgcgaca gccgcgcgcc
     1261 agccgaggcg cagcacgaac acgacggcga tgatggccgc gatggcgagc aggacctggc
     1321 cgagccagat ccagccgtcc gggtactcga tccactcttt cacgcgcgca ccctttccgg
     1381 ctcaccgaac aggccctgcg gccggaagac gagcaccacg atcagcagga cgaagatcca
     1441 caccaggtcg tactgcgtcc caccggggaa gtactgcccg gagagggtct tgatcaggcc
     1501 gatggcgaaa ccgccgatga cggcaccctt gatgctgccg acaccaccga gcacggccgc
     1561 ggtgaaggcg aagatgccgt agaggaagcc gacctcggtg tcgacgttgg tgatgtggat
     1621 gccgtagagc acacccgcga tgcccgccag cgcgccaccg atggtgaagg tgagcacgat
     1681 cgtgcggttg gggttgaccc ccatcagccg ggcggtgtcc gggtcctggg cggtcgcgcg
     1741 catcgcgcgg cccatccggg acttggtgat gtaggtctgc aggacgatgg cgcccacgat
     1801 ggagaccacg atcatcagga tcgccgtcga gccgatgttc acggtgccgt cgaagaactc
     1861 gaaccggaac tggtggtcga cgaaggcgcg ggggaagggg acgggggcgg tcgcgcccgg
     1921 gtagccgagg cggacgacct ccttgaggat gaccgagacg ccgagcgccg tgatcaacgg
     1981 tgccaggcgg ggtgcgttgc gcaggggccg gtaggcgaag cgctccatga ccaccgcgag
     2041 gaccacggcg accacggcac ccccgatggc catcaacggc agtgccagcc accagtcgct
     2101 gcgccagctc ggcgggagga agtaccggta cgtggcgagc gaggcgaacc cgccaaccat
     2161 gaagacctcg ccgtgcgcga agttgatcaa ctggatgatg ccgtacacca tcgtgtagcc
     2221 gagtgcgatg agcgcgatca agccacccag caccaggccg ttaatgagct gctgtagcag
     2281 cgtggccacg tctacctcca agagcggcgg gggcgggctg gtgggcccgc ccccgccacg
     2341 tgcggttgga caagaagttc cggctcagcc gccgaaggtg ccggtctcgt cagccaccca
     2401 cttgccgccg gagaccttgt agacggtcag cagcttgttg gtgctgtcgc cgtactcgtc
     2461 gaacttgacc tcgccggtcg cgccctccgc ggagtacgac tggacgttct tgatcacgtc
     2521 ggtccgcttg gcctcggacc actcgccgcc gccggtcagc gtcttcgaca gcgcgccgat
     2581 gatggcgttg gtggcgtcgt aggagaacgc gccgtacgcg ctgaagtcgt ccttgtacgc
     2641 cttggccttg tacgcggaca cgaacgcctt ggcggtgtcg agcgtgtcgg tgggggcgcc
     2701 gaccgaggtg gccaggtcac cctccttgcc gccgagctcg atgtacttgc cgtcgtagat
     2761 gccgtcgccg cccatcacgg ggatgttgag gcccgcgtcc ttgagctgct tggacagcgg
     2821 accggcctgc gggtactcac cgccgtagta gaccgcgtcc ggcttcgagc cgctgatggt
     2881 gccgatgaca ccgctgaagt cggtgtcctt ctcgccgacc ttggcggtcg ccacgatctt
     2941 ggcgccgtcc ttctcggcct gcttcttgaa ctccgcggcc agaccctcgc cgtaggtctt
     3001 gccgtcggtg atgatggcga tggacttctt gcccgccttg ccgaccaggt acttggccgc
     3061 gaacgggccc tgcaggtcgt cggtggcgca gacgcggaag tagttctcga actggcgctt
     3121 gggcgcggtg ccgtactcgg cgccgcgggt cagcgagggg ttcgtgttgg cgggcgacac
     3181 ctggacgatg ttcttgccct tgaggatcgg ctgcacgctc tgcgcgaccg acgagttcag
     3241 cgtgccgacg acgccgacga cgttcgcgtt ggaggacagg cgggtcgccg cctgggcgcc
     3301 gacctgggcg gtcgcctggt cgtcctcggt ctgcacctcg agcttgtagc ccggcgtagc
     3361 gcacttctcg ttggcctgtg cggccgcgag ctgcgcggag ttccggatgc cgagaccgag
     3421 cgcggacagg ccacctgact gcggcgcgat gacgccgatg accagggtgc ccttgctctg
     3481 gtcgcaactc tggttgttac ccccgccgga gcccgactcg gtcttgttcg tgccacaggc
     3541 tgcgagcaac aacgcgccag cgaccagcac cgcggccttc accgtctggt ttcgcacgtg
     3601 atgtcccttc tccgctttcg tccggacaat gcgtgtaagc atgccgaacc tcgccctcat
     3661 acctgttgga gggttgcgcc ggaaagtagt gaccgaatgc gacgtagtca cgcacctggg
     3721 ctcctcgtga ccagactgca acgaaagtat ggggcggtgt ccgcactccg gacatccggg
     3781 catgaacagc gcgaccatga cccggtctca acttcacaac aacgtgtcac acgctgtcac
     3841 cggcggacct agggtgcggg gcgtgcgact gcgaaaccgg gtcctggcct ggggatccgc
     3901 cgggctcgcg atcggtgctg ccgtgctgtt gctgcgggcg ccggtcgaac cgccgaagcc
     3961 tggaccagcg ccgatgccgt cgccggaacg ggttagccgc ttcgccgccg atgacgtggt
     4021 gctaccggaa gtcggcgcgc cgccggacac tccgcgtgac ctccgggtcc gcgcggcgcc
     4081 ggggctgctg gtggtgtcgt gggcggaagc ggccagggcc acgggatacg aggtccggtg
     4141 gagcggcgcg gaccagtcac ccggcacgcg actggtggcc accagggaca cgcagctcga
     4201 cgggctcgtc gacgggcggg aataccggat cgaggtacgc gccgtcgacg cgttcggcca
     4261 ggtttcggcg cccgcaccgg caaaggggaa tcccggaccg ggtgatactt cctggcggcg
     4321 cggcctgacc ggcctcctcg acgatttccc ggacgattcg agcctgcgcg cggacacggt
     4381 cgggtcactc tggcacctgt ccggttaccg cgggtgcgtc gatctgggcg cccgcgccgt
     4441 tggcgaggta ggactaccga tcgacctcgg ttgcggcgcg gatgaggcgg tcctgcgcgc
     4501 gcgtgcgccc atggttctcg acgagtccac accggacggc gacctcggcc gggtcgcggt
     4561 ggtgaccgac gcggcgggcc ctggtggacg gctgacgctg gacctcgtgc cgggaccggc
     4621 ggaccgggtg gggtccgtgg acggtgtggg gtcgttgccg ccggggacgg tgcgggccgt
     4681 tgtggacgac acgggcgcgc gggtgggtga gcggggcgag ttcgtcgagg ctcctgggcc
     4741 gcgcggggct ggggcgttgc acttgtatga ggtcagggtg actacgaccg gggtgacgct
     4801 gtcgcaggac ggcagggtta tcgcgtcgtc gccggtggtg ccgtcgtggc gttcggcttg
     4861 gttgttggtg ggtgtgcggg ggcctgaggg gcgtcgggcg cgggtacatg tggcgtcggc
     4921 ggggttcacg ggggtggcat cgccggttcc gcaggtagtg gagacgccgg tcaacctggc
     4981 tacccggcag gtgttggacc cgtcggcaac ggcaccctcg gcaggcatct tgcggcgtcc
     5041 actggctaca gcactgtcgg cccgtcttgt cgtgaccatg gtggtgtcac cggggatgga
     5101 cgtgggtgct agctggatcc aactgggcac ggcagtactg cccgcgcgtc cggtagcgcc
     5161 accgccgcct gagcctgggt cagtggtaac cgtgatcgcc gacgtaccgc agtctctatt
     5221 gggaggcaac ggctccgact cgttgtcacc tctagtcgta cgcgcacccg gagccggcca
     5281 gggcgcgcta gtacaagaga gctacctgga actggtcccc ggccccatcg cgtcagtcag
     5341 aacaacaacc caacccgccc gcaccaaccg ccaacgccca accgtcaacg ccctgccgac
     5401 cgccacgctc accctgggcg actccacggg ccgccccctg acaacccctt ccctaccagc
     5461 acagggaaga ctcgtcctca cagtgaccct taacggcgcc gcagcccaat gggacaccgg
     5521 cagtctggag ggcgtacagg gcttccagct atgggtagac ggccgaatga ccgccagcct
     5581 ccccacgtca tcccataccg gagcccccgc gggccgctac gcgatcccgg tagccctaac
     5641 aggccgcgcg gtgggcgagc acgcggtaga ggtaagagtc atcggaacca acggcacccg
     5701 cggctcaacc ctcacccaat tcaccaccac gtgagctacg tgatgttgtc gaccacggcc
     5761 tcggcgacgg ccttcatggt ggtccgccgg tccatggcgg tgcgctggat ccagcggaac
     5821 gcctcgggct cggacaggcc ctgcttgttc atcagcagcc ccttggcccg ctcgatgacc
     5881 ttccgcgtct ccagccgctc ggtcagcccc gcgacctcgt tctccagcgc ctgcacctcg
     5941 gcgaaccggc tcaccgccag ctcgatcgcg ggcaccaggt cgtgcttggc gaacggcttg
     6001 accaggtacg ccatcgcccc cgcgtcccgc gcccgctcca ccaactcgcg ctgcgagaaa
     6061 gcggtcaaca tcaccaccgg cgcgatccgc tcccccgcga tcatcgtcgc cgcctcgatc
     6121 ccatccatcc gcggcatctt gacgtcgagg atcaccagat cgggccggag ctccccggcc
     6181 aaccggacag cctcctcccc atcccccgcc tccccggcga cctcgtaccc ctcttcccgc
     6241 aacatctcga ccaggtcaag ccgaatcaac gcctcgtcct cagccaccaa cacccgccgc
     6301 ggggcaggcc gggcctcggc agccagatcg ctcaccgtgg tcctcctcca cttaaccagg
     6361 aaagacagag cctgaaccat accgccaggt agccccccac cccctcccca ccacgcgtga
     6421 tcgcgctgac acccaccccc caccccgcca caccccatcc cgtagagtca ccccccgacg
     6481 cccccgtagc ccaaccggca gaggcagcgg actcaaaatc cgtccagtgt gcgttcgaat
     6541 cgcaccgggg gcactcccat gacctcacag aacaggccct gaccagcgcg aacgctgaca
     6601 gggcctgctg cttgcctgtc cgactgcgtc cggccggatt cggtcccgta cagctgatct
     6661 ccccctaacc accgccacga cgacccgtgc cctttagggt ctggccaatg cgcttgcgcg
     6721 cttggtgttc gagtcttgcg atgaccggtg cgtggctaga gcagcactca gatcgcgtgt
     6781 cccgtccact cgacgatctg tgcaggctgc accgcaacgg ccaaaccata aggacgcgca
     6841 cccgagcctc aggtcggagg cattcgtccg aggtgagcgc ggcgcttagg accgcgtcgg
     6901 ttaccggtgt cggtccacac agcgccaccg atcggggcag cacccgatag atggcattcg
     6961 tcccatcctc ggacagcccc cgcccagcat cgccgcctct actgcctcaa gtgcggcgag
     7021 ggtatagata cgacgtagtc ccgccgcatc actggcccgc cgccaggcca gcccctgacc
     7081 gcaagtcgac gcgaaccgat atcgccacgt agttccgatc cctcgtcgcg ccagcgcaag
     7141 ttcgctgagt ggccttgtcg tcgcaggtct ccgaggaact gccaatcaat ctggaccagg
     7201 cgaagtgaat gcagagagcg ggagcagatc gaagattgtt cccgcaccac ttttcacccg
     7261 cgcgtggcac tcactccaag cagtccgtac ctgcggaagg gcgagctggg tcgttcgaca
     7321 tcttctcccc gggacacaac ctcaggtccg cccgacaaac ctggccttgt ccttggaccg
     7381 ggccatgcgc acacactatc cgaccctacc atggggcctc aagaacttcg cactccgtgc
     7441 tctcgttagc tgatgtttag cgcaccaaga gccgctctga ctacgttcgt tcgtacatgg
     7501 caagtaccac atatcggagg cagcgccttg ccgcagcgct gtgttgacgc aacttcgagc
     7561 gcgtacggct agccttgcag cgtttccacg ggactacctg attgaagtcg acagcagcgg
     7621 cgcatacttg agatccctct tcggaaaagg gtaggatgaa caggaaatgg acggcttgac
     7681 atctcaggga ttgcgcccgc catagcagca accctgtcct catctgcatc agctgccgcg
     7741 gcccatgcct gcaataggtc cggatcacgc attttatcaa ccggccacag gcttaccctc
     7801 gtgaccggca attgctacat atagtttcgc gatacccttg acacgaattc attcggacgg
     7861 catgctcaca tgcgagatca ctagcgttct ggggagatta tgctggaatc gatccgggtt
     7921 cgaattcgcc caataatttg ccaatagggc acttaaccgg gcgatcacac tggatggtcg
     7981 ccaacttggc acctccgaca cgggacaaca tgatctggat cccggacaac cacagatcaa
     8041 cgaagcagaa ctatgacacc gatctctaca gccatcagct tatagacacg gcccattggg
     8101 gatgatgtgg tactggttct gcgaccggac gcctacgtcg ccgagacacc aaacggagcc
     8161 ttcgtgctca caaacagcgg ctcgtacact tttaccggac atacgatatt cgcgctccta
     8221 acgacaatca aaccatacat caacggcgaa tatacacttg atcaactcgc cgcccgaatc
     8281 aataagagag cgcgagaagt agcggttaaa ctgctgaccg gaatgcttga cctcgacatc
     8341 gtgcgggata tcgagcgtct caagattcaa agcagtcaac cggaggtccg gttcatcgag
     8401 tactttcaag atgacgccgc ccgaacgtac tcagagtact gcagcatgtc tgccctcatt
     8461 attgggcgct cgccactcgc tcaggcagtg gaagcggcct gtcgattatc aggactgcgc
     8521 accaggagtg tcgaccaaac tgaagatcgc gaggccgccc ctatggacag cgccgcgatg
     8581 gacgacgtga tcttcgtcgt tggcggcgaa ccggactacc actccaaggt cgaggaggaa
     8641 ctcagctgcg accacgacgg ggtgttggtc cacgcgacga caatcggaga agcctggttc
     8701 tgctgcatag gcaaggcaga cgaagccgtg tgggcatccg tcacgcagag acttgccgcc
     8761 agacgggcac ccgcgcaggc cccgcgggca tctcccgagg gcagaccaga cgaccacgcg
     8821 gtacgagtgt tggctgccca gctcgtgcac aacgctttcc gactgattac cacgccatca
     8881 gcagcacgtg gtggcgtcaa ccgcgttgat caggcgacgc tggcaagcga accgatatct
     8941 tacttgcggc acccttacac gctgcccgct cagccacgca ccgccacgca gttcgctcat
     9001 cgaatcgcca ccctcgccgc tagtcccgaa ctagacgaag aggcgttctc ccgacacgca
     9061 gtttcgtgta ctggagagtg gaccggagtc ttcggactac cgactgaacg cgagttcgcc
     9121 caaacgccac tatgcgtctg ccagatcgaa gtttcagcca cgacaggcgg cagcacttcc
     9181 cacgtcaccg gcgcgggcct cgacttcgcg gccgcccggt accaagcctc tttgcgtgcg
     9241 ttcgcgagct acggatcaac catattcgac cctcgacaga tgcttgatat caacgagcaa
     9301 ccgctcgtac agcgcgcaga gggccttgat ctcattaccg aggacctaca aagcggtcgc
     9361 ctcgccggat ttgtctgggc ctacaactta gctacctcca gaccgatgct gctcgatgca
     9421 gtgcgcgcgt ttcccaacac ggatgagggt tcacacttgg gcagcgcggc agccgcctac
     9481 agctggaaag ccgctatctc cgctgcgctc atctcgcaat gccataggat gacgctgctc
     9541 gaacaaactg ggtctgcacc ggaactcgat attacgaaca tcccacccaa ttcgcaactt
     9601 gaacactacc gggtaattct ctcgaaaatc ggcccggtgg ttgttcgcga cattaccggc
     9661 tctctagagg taccaacagt catatgtctt ctcaagggtg ttcaccttgg cagcggaagt
     9721 ggtctctctt acctggacgc ggtgaccgct gcgatggaag aggcgctatt gagctaccaa
     9781 gcatcagcga accagcaacc tgagtacgct ccgccgaccg cgccgaccgc accgcaggca
     9841 agcagatctc ggctaccttt tccggtcgac cgaccaagga ccgtggactc cgtcatccag
     9901 accttgcacc gaagcggcca tacaccattg gtggtgccac tcgaccatga tccagaggta
     9961 gccgcgatca tgccttacct ggttcgggtg gtgctgagtg atggccgctg aacacgcaac
    10021 gccgatagcg attctcggta acggactgct ggccaacgcc ctgatcaagc gaccaggcgt
    10081 ccatcaggcc acttcagtcg ccgaggtgga tgccggatgc cggatgatcg ttgtcgccac
    10141 cgacggctgg gatgacagcg cctaccactc ggttcgagcg gtcgctgccc gattcggccg
    10201 gccgtggcta cccgtccgaa ccgaactggg caggatcgtc atcggcccag tcgagcaacc
    10261 cggcgtacca ggctgcggca tctgcgtcga gcgtcgccgt gcgcagatca gcgcgaccaa
    10321 cgacggcgtc gaggccgtcc accgcgcaca cggtactgtg ctggcgaccc ggtcctcttc
    10381 ctggctgacc acgctggccg cggacgtcgc cacgtcactc gtcctacggg aagccgaccg
    10441 cctgaccagc aagcaggacg agccgagagc cgcgtgcggg tatctagaca tcgacttggc
    10501 gagcttggtt gttcgaaggc acgagttcct tcctgaccct ctttgcccaa actgcggata
    10561 cctacccgac gacagccccg tgctcgcaca catccgccgg accaggcaac ccaagcccgc
    10621 ccccgaccac taccggattc gctcggtggc tgatgagctg cccgccctga tgggactcta
    10681 cgtcgactcc gagtgcggac tcatcaggtc ggtgtcgaag gaccaagacg gcggcgtggt
    10741 gatcgccgca gccccggtcg ggcttcggat cgaggcacgc gagttcgggt tcgggcgcag
    10801 ccgaaactat cgcgacagcc aggtgacggc catcctcgag gcgctggaac gctatggcgg
    10861 cgttcggccc ggcggcaaac ggacctcggt acgcgcgagc tatgccgagg tacgcgacaa
    10921 cgccgtcaac ccgaggactc tcggactcta ccccgctgat cgttacctgg cgccaggctt
    10981 ccggttccag ccgttcagcg agacgcagcc ctatcgctgg gtgtgggggt attcgttcgc
    11041 gcgccaggat tcgatcctcg tgccagagac ctatgcctac tacggcgtct ctcggctgcc
    11101 agaagccgat atcccattcg tcttcgagac gtccaacgga tgtgcgctgg ggagctgtgc
    11161 ggcagaggcg attctgcacg gggtgctcga gatcgccgag cgcgatgcct tcttgatggc
    11221 atggtatgcg cgactacctg ttccacgaat cgatctcgac tcggccgttg acaaggccat
    11281 cccgctgacc gccaatgccc tgcgggcgga gaccggctac gaggtgatgg ccttcgacac
    11341 gacgacggag cagggcatcc cctgtgtgtg ggtgatggcc gtcgacccgg tgggcgacgg
    11401 tgaacgcccg aaggcggtct gcgccgctgg agcccacctc gaccccgagc acgcgatcga
    11461 gaacgcgctg aacgagcttg gccctatcgt ggccgacctc atccgccgtc accggttcga
    11521 ccgtgagcgc gcaaggagct tggcgacgga cccgggactc gtggtggaga tggcagacca
    11581 ctcgctgctc tacgccaatc cggaggtgtt ctcccgcttg gacttcctag cgagctcggg
    11641 accctccata cctatctcgg cgatggctca gcccaccgcg ttccgcaacg acgacctcga
    11701 ggacgacttg gacgagctcg tgcggcgcta cctgaacacc ggtctggacg tgatcgtggt
    11761 ggaccagacg actcccgagc accgcgcggg tgacttctcc tgcgtaaagg tcatcatccc
    11821 cggcacactg ccgatgacct tcgggcacga cctccgcagg gtggatggtt tgcccaggtt
    11881 gtatgacatc cccagccgac tcggcagacg actacggcgg caggacgtga acccccatcc
    11941 ccaccctttc ccatgaggat cacatgtacc tccagatcgt tgcttgggac ctgtctcgtt
    12001 cgcaagccac cgtagaaggc ctcaggggct acctcaagga ctatgccgtc gacgcgtatt
    12061 cgacgctgga cgggatggcg atgaaagttt ggttcggcaa cccggagaag caagtgtggg
    12121 gcgctgtcta cctctgggac tcattggaac acgcacatgg catcacaacc gtcacccgag
    12181 tcgtggacct gatcggctac ccaccgacct cggtgagcgt gttcccggtc gaagcgatct
    12241 cacgtggccg aagtcggcac gacgtgatcg tgggtcttgg cctggcattg gaaaactaga
    12301 agcagcgggg ggacgcagtc gatgagacca ggtgcggaca atgccatcgc gggcgaagca
    12361 cggcccagac ttcgtcatga cgtcgtgctc gcggacacgg gcgacggggt gctgatccgg
    12421 acacccgacg ggcacctcgt ggtcaagggc cccgccgcct acccgttcgc cgcaaggctc
    12481 gccccccatc tcaccggtgc atggacggtc gccgaactgt gctcgtcact gcctgacgac
    12541 aagagcaggt tggtggcggc gttcgtggag accttgctcg aacacggttt cgcccgggac
    12601 acacggtcgc cccgatcagg gccgcgcaac acctcgtacg cgacgcagat cgacctcatc
    12661 gaacactacc gggatgacgc ggaagaggcg ttcctcgcgt tccagaacgc aaccatccag
    12721 gtcgccggag ccggggcggt agatcgggcc acagcgaaca gcctgatgcg caacggtgct
    12781 cgcaacgtca ccgtcatcac gacaccggtt gaaccattgc cagctgacgc cgtgtgcgga
    12841 tcggccatcc ccttggagac cgcgcccgca ccgctggtac tgcccgtact cacccacgcg
    12901 ggcaaggcgt tgctcggtcc ggcgactcga ccaggcggtg agtcctgctg gaactgcctg
    12961 ctgctgacac tggaggtgag cgaaagcgac accccgttgc gacagccgca ggcagattac
    13021 gtcggcaacg cactggggac cgagctgttc cgaaagctca cagggatccc cacaccgacg
    13081 gacggcggcg tggtggtgat cgatttggac acgttggaat gcacgcacga gcgagtgttg
    13141 cgccacccat cgtgtgcgtt ctgcaccaga gccgaaccgg tgcccgtcgt accggcgcga
    13201 gccgtgcaag agcccgccgc acagtttcgc gcaccaagcc gtttaatgct ccgtgccctc
    13261 gttggcgaac tcgaccggtc gacctcaccc acaacgggac tgttgacggg gttccacgac
    13321 acctcggtaa cccagtcacc gctcaaggta gggcaagtca ggaccaggtg cggacggacc
    13381 atcaccgcgt tcgacccgca tcatctaccg gttgcccgac agcgagccgt ccacgccgca
    13441 ctactggtcc acgcgagcag gttcaccagc ggcggagtcg cagaaccggc agcaccagtg
    13501 cccccgaacg agcttctcct ctggtccggt cagacctcca ctcgcttctc cctttggttg
    13561 cccatgacct ccttgctatc ccggacatcg cacttcgttc ccgccgcggc cgtccatccg
    13621 gtgactgtcc acaacaacag tggctccttc gtccgcaccg gtgcaggtga cggaatcggt
    13681 cccaccacgg ccgaggccac cctacgcgga ctgttgaccg cgttcgctca tcacagtctc
    13741 ggcggcaccc atgaggagat ccacctccgg caggccgatc tcgatccgga gatcgatttc
    13801 ctgctgcgga cactggctgt tctcggtgtc acagcgacct tgaccgacct ggctccagga
    13861 atggcacacc gagtagtgcg ggctcggagc agtgattcag gcttgacgag tatcggcgcg
    13921 gcactgtcca ccagagccgc aaccgtgtcg gcgctacgag atctcctcgg ccgcatccag
    13981 ttggcgcggg aaggtgtgcc gttcgacgcg ggcaatcccc tcctatccca tcccacctgc
    14041 tccatctacg ccgcctgcgc actgtcggca gatgatgacc cggcaggact gtacgagaac
    14101 ctgatcgctc gcggactgga cgccttggcg gtggtcacca cgccatccga tgtagcccag
    14161 ttgggattgg tcacggtgcg agtcctgctg cgccgattag acagagtaca tcgacctagg
    14221 cccgtgcgga ggaagacatg acgctgccgc acctgccgat ggaccgggag aatccgttcg
    14281 acccgcccgc cgggctcgca tcggcacgcg atgagggacc ggtcgtcccg atgaggttcc
    14341 ccgacggcca tcgaggatgg ctggtcactg gacacgcggc ggcccgagag atcctagcga
    14401 gtccactgtt cagcaatcgg ccggagctga ccaggtcgat agtctccgtc cccggcggta
    14461 ccggcgtggg gaccacagcc cctccgggca tgttctcccg aatggacccg cctgatcaca
    14521 cccggatacg caagctgctg acccggtggt tcacagtgcg caggacgcgg gagctggctt
    14581 cgcgaatcga gcgaatcact gacgaccatc tggaccggat ggcagcgcac ggcccgccta
    14641 ccgacttggt ccacgcgttc gccctgccga tcccgtccat actcatctgc gagctcctcg
    14701 gcgttcccta tgcccagcgc gaacggttcc agcgcgacac cgcggtgctg ttcgacctcg
    14761 actcccagcc tgatcgagtg aatgccgcgt ggtcgtcgct gggagggctg ctcagtgcgc
    14821 tggccaggga gaagcggctg cggccgaccg acgacgtgat cagcgagctg gtcggcggag
    14881 gagacctgac cgagcaggag gtggtcatgg tggcgatagt gctcctcgcg gcaggacacg
    14941 agacgtcggc caccatgatc gcccacggga tcttcgccct actgcggcac cccgaacaac
    15001 tcgcgcggat ccgtgccgac cccccactgg tggacaaggc agtcgaggag ctgctgcggt
    15061 acctcagcat cttccacatc ggtccggccc gcagtgcact cgccgatgtc ttggtcgccg
    15121 gacaactggt caagcggggg gacaccgttg ccatctcgct gcctgcggcc aaccgcgatc
    15181 cgtcggagtt caccaacccg gacgaactcg acgtcgggcg cgaccacaac cggcacctcg
    15241 cgttcggtca cggcatccac cagtgcctcg ggcaacagct ggcgcgagtc gagctgcggg
    15301 tgggactggg tcgcctgctg cgccgatttc ccgacctgcg actcgcggtt ccggccgagg
    15361 acgtgccggt gcgaggcaac atcgccgtgt acggggtgca gagcctgccg gtgacctggg
    15421 ggcaaagatg atccaggatg ccgcagccat caccgactac ttccgagatc gactggtcag
    15481 atcagaggtg atcgctccgg ccatcggtgt tctcggttca ccgcgcccca gcgcgctcga
    15541 cgaggtggtg ccgatccacc tggatgaggg gctcgtggtc ctcgggccta tccgcgcgcc
    15601 aggaggtact ggcccctgcg ccgagtgtct gcgcctgcgc tgggagcagc gagctggggc
    15661 agaccagcca cgagagtcgg tccggatcgc gaggtcaccc cacctcacgc ccttcatgat
    15721 ggaggcggtc ctgcagctct ggttgtgctt gcgggcccgt cgtcccaagc ccgggaccgg
    15781 gaccgggacc gcgccgcttt accgcgtcga cctgccgtcc gggcgagtcg agcgaatggc
    15841 cttgcttgcg gacccgtcct gttcggtttg cggacccccc gcacacgatc caccgatcga
    15901 cttccggctg gtaacccgcg agaagcacgc cgtggacacc ttccgggcca gcgcactcgc
    15961 cgacgtcgac ttaccggttt cggcgctggt caactcggtg tgcgggctca tcggggcgaa
    16021 ggtagagcta ggtctcccct cgccgaccac ggctccagcc ttcggttcgt tcactacgca
    16081 ggcccgcggc ggcgtacacg acatactgtg gatgggccag accaaccggt tcgacgacag
    16141 tcggacagcg gccctgctcg aagggctgga acgctatgcc ggtgtgcgcc accgagcgag
    16201 cagctcggag atcatcgagc ggttggtcga tgtcggcgag cccgcggtcg acccgcgcga
    16261 ctgcgggctc tacgccgacg ggttctacca cgattccggt gcctacaagc ccttcgaccc
    16321 ggagcggccg atctcgtggg tcgacggcca ttcggtgcgc gacggtcgaa ccgtgctggt
    16381 tcctcggcag atcgcgtact tcggcgaggc cgccaccgga caggtgttcg ccgacggatc
    16441 gtcgaacggt tgtgccatcg gtgcgaatct ggaggaggca gccctgcacg ggctgctcga
    16501 gctggtcgag cgggactcag cactgctggc ctggtacggc ggcggtccat tgcccgagat
    16561 cgacccggcc agctgcgacg acctacagat ccggttgacc gtcgaacagg tgcggctggc
    16621 cggattcgac gtccggctgt tcgacgccag gagcgacctg gccatccccg tggtcatcgc
    16681 ggtcgcgatt cgcctcgatg gagggcccgg tgcgcggacc ttcgcctccg gcgcggacct
    16741 cgaccccgtg ggcgccatcc ggtccgctct gttcgaagtc gcctcctacg ccccggacct
    16801 ggcaggccgg gtgctcgctc gactgccagc agtcgagcgg atggcagcgg acttcggaaa
    16861 cgtggtggac ctgatggacc actcactggt gcacgggcta cccgcgatgg ccacgcattc
    16921 ggacttcctg ctggcaccca accgaaagct gccggtgcgc gagctctacg cggatgtcga
    16981 cccgcgcggt ctagacctgc tcgacgacct ggactactgc atcggccagg tagcgcgagc
    17041 cggacacgac gtcgtggtcg tggaccagac ccggccggaa caccgagcga tcggcctgcg
    17101 cgcggtacgc gtggtcgccc cggggctact cccgatcgac ttcggatggc gcaagcaacg
    17161 cgcgttgaac atgccccgcc tacgcaacgc gctccagcgg accaacctcg cgagggacgc
    17221 cccagctgac ggcgaaccgc atcgcgttcc ccacccgtac ggctgagatc gaacccgagg
    17281 aaccctccca tgttgcgatt gctcttgacc ttcgacgatg cgctccgcat acggatggca
    17341 ccgagcgcgg acccgctttg ggagacccgg ctgagcctgc aagccttgcg caggcccgtc
    17401 tgcggaatcc acatcgacgc ttggcgtcgg ggtatcaaca caacactctc gcgggatcag
    17461 ttggtgcgat cagccttgcg gtttctcacc ccgcttgtcc cggtcgaggg ctacgtcccg
    17521 gacttcttga cgccaaccgc aggcaatcgt ggcgtacgag caggaattga tgccgttctg
    17581 gagacaccac ccagtcgagt caagtccgag cttgcgatgc tggtgaggtc tggaccggta
    17641 ccccggcacg tccacgaact ggccagtggt gatctcggca cgatgaagag gctcggttgg
    17701 gcgctgggca cttaccacga cgcggtgatc gccccacact ggggccgagt ccaggcgctg
    17761 gtcgacgcgg accgcgcaca gcgagcccga acggtcgcgg accagggcgc cgagcaggtg
    17821 ctggcaggtc tcgacggtgt gcggtggcac cctccccgcc tggaggtgga cagccccgtc
    17881 gaccgggtgc tggacctggg cggaagcggg ctccaactgg tgccatccct gttctgccag
    17941 ggaaaacctg tgatgccggt cgacgaaggt ctaccccggg tactggtgta cccgatcgac
    18001 ctcggaaccg gctggtcatg gcacgaggac aagctcgacg ccgaccagcg agacgtgcgg
    18061 gcgctgctgg ggtcgaccag ggccacgatt ctggaacacc tggtcgcccg tgaccgcttc
    18121 acgggtgagc tggccagaat cgtggcgatg accccggcga ctgtcagcaa gcacaccgct
    18181 gtcctccggc acgccggact catcatcagc acccaaagcg gacgccatgt cacccaccgc
    18241 ctgactcgac tcggcgcggc actgctcaac agatcctcac gaatatcgtc gccagaggga
    18301 aaacgacggt ctgtgccatc tggagacgtg caaaaatgat ctcggcggtt tcaccgccat
    18361 gaacgagagg agtgccttta atgagcgtac ccaacctcga cttcgatctc gagaacctcc
    18421 ccatggacgt tttcgacctg ggccagaacg gcctgacgat cgagtcgctg acctccggcc
    18481 acggcatggt ggagaacggc gcttccgtgc cttgccctag cgtctgcagc acgtcgacca
    18541 tctcgtgcag tagcagctga gaagagccgg tcgggtcggt gatcttcacc gacccgaccg
    18601 ggtcgtcacc gccggacacg gggaatcgag acggaatgag cacgctaccg accttgcaca
    18661 acgggacccg ggtggccaac ccgctgatcg tccgccgtgg tggactgccc ttgaactcgt
    18721 tggaccgcct gcggttcgag cagagtttcg ccgcggccac cgagatcgtc cgatcgcgtg
    18781 atcgtctcgt cgcggaaggc accacactgg cggacgcgct gtactcggtg atcggtgagc
    18841 tggcggacgc tgccggaaag ccagggctgg tcggattgcg gcgagctctg cacagcatga
    18901 gaccacctgc cgccaaggag tggaacgaca ccacgtgctc agcgctcccg tcggagatcg
    18961 ccgccagggt atcggcatgg gtcaccgacc tgcggcgcca cgaacgggaa cgtgctggcc
    19021 tcgccgatgt cttggccgca gagcggtgcg agaagcagga ggtgctgcgc tacgagagcg
    19081 cacaacatgg ctttcgccgg gccttgtcgc aagcgagcgc gacgttgtac gccgagctcg
    19141 acaagtggct ggccgacccg caacaccggc ctcgtgagca ggtgatggtc cggctggtca
    19201 agtacatgtc ccgggctgcg atgaagacca gcccctacag cacgttcacc gtgaccggcg
    19261 ccgggacgtg gacggaggcg ggtgccgccg cgcacttcac gaacgcgtcc gtcgccggtg
    19321 tggttgagtt ggacggtttt ctcctacgcc agctgagcgg tctgctgtgt gaagacccca
    19381 ggctagcccc gttcctgacg gttcgggtca atccaagcgc cacggtcagc gacaaccggg
    19441 tgacgttcac cgggccatcg ccgcgggagc cgatagtcac catgcccgtg aatgccgccg
    19501 tgcgcgcgtg ccttgagatc ttgtccgaac acccgcccac gtcgttcacc gaactgcacg
    19561 aacgtctgtc ggacggcgcg gacccggccg tggtacggct gtttctcggg gcgttgctgg
    19621 acgcgggtct gctggagcgc cagctcccct tcaccgacca ggaactggac ccgctcgagg
    19681 tgctgtgcga ctggactacg accgttggcg gagacgactt cacccacatc gtgtccttgc
    19741 tccaacgcgt ccgaagggca ctacgggcgt cggtgccggt accggacgtc gaggcgcagg
    19801 tcgcccgcca gaacgagctc aagcaggctg tgatcgacct tggtaccggg ttgggcctgc
    19861 cactggacca cacccagagg cagggcagct tcatgttccg tgagaacgcc gtgttcacca
    19921 gtccggtggt cgagtgctcc acggcccact ggcaacccgc attggacgac ctcgatgtgg
    19981 ttcgcaggtg gatggcaccc tttgacttgg cgctacccct tcggatcgtt ctcggcacct
    20041 tcgtcggaga gcggttcggc cagggtgcgc gagtccccct cttggcggtc caccgggccg
    20101 tccaggaatc ggtggcagcg ggcccgtcat cgagcatgag cgacgccgag caggagatcg
    20161 tgcgatttct cagcagctcg ccgctcgatc agatgacagg ggatgcccac agcccggttg
    20221 cccggctccg gcagctcaat cgagtacgtg cacaggctcg tggcgcgctg ctgagcggta
    20281 cgcgggcacc cactgccacg caggtcgatc ccgtgttgtt gagcgagatg atcgcgacgt
    20341 ggccactgtg gatcgcagca cccaggtcgt tggcctgcta tgtgcaactc cttcccgggg
    20401 aggagatggg cctcgtcctc aactcggccc acaccgggca tggccgtggc cgcagcaggt
    20461 cattgcagtt gatcaaagat gcgggcggaa ccacacctcc gctcgccatc gagcacaacg
    20521 cggtcgggac acctgtggac gctgagctag gtggcctggc ggtctcggcg ctcaaccggc
    20581 gcgtagcgag cctgccgtac gagatcgact atccgctggc ggtcagcggc cgcccggccg
    20641 aggaacggat cacgctgggt gaactgctcg tggtgcacga ccccgagtca caactggtcc
    20701 gcctgttctc ccccgcgctc ggccgagacg tccgatccct gcacgtgggg atgatgtcgg
    20761 acttcttgct ccccccggtc gctcggctgc tgacacaggc attcggtgcc acccactacg
    20821 tgcacccgag catccctttg gtggcgaccc acagcgatct caccaccccg gcggggatcg
    20881 tgcaccatcc ccggatcacg gtcggtcggg ttgtcgtgca acgtgagcga tgggtcgtgc
    20941 cgatcaccga ggtgcccgtt cgggaaaagg gagagagcgc agactcccac ctgctccggt
    21001 tggtcgactg gctgcacacc acgtccatcc cggcgcagtg cttcgtccgg gtgtggaccg
    21061 gcctgtcgac gagtcacgaa ctcgggccga acgggtggga gaactgggtc ttcgacaagt
    21121 cgcgcaaacc tgtctacgtg gacttcgcca actggtacct ggtgatggcc ttcgacaaga
    21181 tgctgcgtga ctcggctcaa gccgtggtgt tcgaggaagt tctgccctca cacgcgggag
    21241 catccgccac cggtcaggac gatcgacgag caacggagtt cctcgtcgag ctcaccgggc
    21301 aggtcgacca cgatgcatga caccggatac gtcagcgcac acgcgttcta ccaaggcgac
    21361 ttggacacac tcatcgtgca agggctcccg ggcatcctcg atgacctgcg tggcaggcgg
    21421 ctcgtggacg acttcttctt cctgcgctac tgggatggtg gcacgcacct gcgactccgg
    21481 gtacgccccg gcccggatac cgagcgccgc ctggtcgagg atctcatcac cagccggttc
    21541 agcgagttct tcgccaggtc gcctgcgaac cacaccatgt cgcaggagga gtatggcgct
    21601 ctggccgcgt cactggccga gtgggaaggg gtcccatcgc acgtcgagca gctgtacccc
    21661 aacaactccg ttgcgctgat cccctatcaa cccgagcatg agaggtatgg acgcggcgcc
    21721 tcgctggctg cagctgaacg gcatttcggc gactccagca ggatcgcgct agccatgctg
    21781 gcccgggggc tatcaccgga tgagcgcacg accgcggcag cgtcgatgat catgctggct
    21841 tggttcagcg ttgagccaga ccctggtcgg ctacggcggg cgatcactgt gtcgaggtac
    21901 accgataccc tgttgggtaa ggagaaggac ctggtccaac gcggccacgg ccaggtcgtc
    21961 cggttggccc ggcatatgtt cgccctctcc gctcacgcac cgggactgcg caatgatggc
    22021 ctgctcgtgc gttgggcacg atccgcggcc actctggtgg acgagctcgc agcagaggtg
    22081 gcgagcgggg ccttctcccc accgagccgc ggctgggagg gctccgaggc ggcctcgacc
    22141 atcgagccgc ggttacgcgt gcttcctgtt atcgacatct gcgcccatct cctgtgcaac
    22201 cggctcggcg tctccatcgc cgaggaagcc gttatccggg tacgcctgct caacgcgctc
    22261 gagactcttt ccatggagga cgtgacgtga ctcagtggca cgcggtgcac atccactacc
    22321 acgacgatcc ggatcccttg atcatcggtg gcatacgccc gctgttccaa cggctcgccg
    22381 gagtggtgac cgggatgtac tacacgaggc actggcgcct cgggccacac ctgcggttgc
    22441 gttttcgctg cacggagcgg gccttcgcac gggctgtgcg ccctgcggtc gaggacgtga
    22501 tcggcggttt cctggccgct cgtccctcca cgagcgagct ggaccctgac tcgttcttga
    22561 cggcacacca acgcttggcg gatctggaac aagaacctgg cgctttggtg ccctggcatc
    22621 ccgacaactc gttccacgtc gctgaccaga ccccgcgagt ggaggtgcac ggcgggctcg
    22681 ccatggcgga cttactggac gacttctact ccgacacgac ggaactagcc ctgcagacaa
    22741 cccaacgagt accgcggggc agcgcgcgcc tggccttggg gttcgacctg atggtcgcgg
    22801 tcgcgcacgc attgtccgga gtgggcatca ccggagggtg cctgtcgtac cgttcgcacg
    22861 cggaggcatt cctatgcacc ttccccgaag gcaccggact gcgtcccgca tgggacgacc
    22921 actaccggct gcactcgagt gctctactcg cccgcctgcg aaacgtgaca gccggattgg
    22981 gcaacggcgg agcggcggag tcacccatca ccgcctgggt cgaggtcctc aacgattacc
    23041 agggccgggc aacgcggctg atggaccaag gactgtttgc catgccccaa ggcgacgcta
    23101 ggtcagaact cgacctggcc cggagaagtc cactgcacca ggcaggattc gccaacccgc
    23161 ggtggctgga ggtacgcgag tcggcaggct tcctgctcta ccgactcatg atcaactaca
    23221 cctacctgca cctgagcagg ctgggcgtgg cgcccgtgga gcggtttcag ctatgccacc
    23281 tcgccgctag tgcagtcgag gatctccacg gtgtctcggc gctcagcatg atgacgtacg
    23341 gcgtcaacgc ccccctgccc gaaaccaggt gacaccatgc gatcgagccc tgtgaacgtt
    23401 gccacgacca gcgagtacac cgagatgttc cagctacgcc ctggggtgtt cagcgcgagg
    23461 tcggcgaccg aggaggtcca cctcgtgcgg tggcagctct ggcagcacga cgagtcgttc
    23521 ggcaagctct ccgaggacca ggctagagcc ctcgagcggt tggccgcagg tccgtgctcc
    23581 gctatggacc tcagccaggg cgtggacgag cccgcgcccc tggtgcgggc gttgcgggca
    23641 ggcggctggc tgaccacaat cgtgtacgag ggtgaccgcg ctctgtacac ggtcctaccg
    23701 ctcgacccgc cccccgccga gacggtcacc tcggagtgcg agctggtgtt gtccaggttc
    23761 gccgtgatgc ggcgcgaagg cgatggcctg gtagtggagt cacctgtcgc ctgggctcag
    23821 atgcacatcc acgacccgca gctggccgcg atcttgatgg gcgcggatgg ggggtctgcc
    23881 tcgggtgttc gcaccaggtt cgagaaggac ctacgcctga gtgggctgct cgtaccggcg
    23941 gggagtgagg aaaccaatcc ggccagcagc cagtggcgct cccatgagct gtggttccac
    24001 cagcggagca ggaggggcaa tggagggtac ttcggcgccg ggtatggccg cacccagtgg
    24061 gcgcatggtg cgatggatct gttgcccgct cgcaggacgt ccttctccgc ccccgccatc
    24121 gaactctatc gacccgagtt ggcggcgctt cgcctggagg acacgacttt gaccactgcg
    24181 gtggaagagc gcagatcggt gcgggtgcac gacgacacca gcccgatgac cgccgaccaa
    24241 ctcggcgagt tcctgttccg gtgcgctcgg gttcgcggta cgttcgtggc cgacggaatc
    24301 gagtacgcga gccgcccact gccctccggc ggaggcgtcg ccgagctgga gctgtacccg
    24361 gtcgtgcgac aggtcgaggg actagccccg gggatgtacc actacgactc ccacgcccac
    24421 cagctccgga tggcccgagg acccggtcac gaggtcaccc gcttgttgcg caccgcggcg
    24481 cacactgcgg tcgtgcagac aaggccccag gtgctcatag tcatctcggc ccgcttcggc
    24541 aggctgatgc gaacctacga agagatgccc tactcgatcg tgctcaagca cgtgggcgtg
    24601 ctctaccaga ccatgtacct cgtcgccaca gcgatggggc ttgccccctg cgggctcggc
    24661 ggcggagacg ctgccgcctt caccgccgcc atcggtgccg accccctgat ggaagcaagc
    24721 gtgggcgagt tcatgctcgg cagccgtccg cccggggacg agtacagaga cacctctgct
    24781 cacgagcccg ctgagtgatg accgaggtcc gaacagacag acctagccct cccctccgcg
    24841 agacggcatc ggacagctcg ggccgtatcg gcccgcttca gcgcggccca cagatgtcga
    24901 ctcgcagtaa cgaaccagaa gccagtcgtc ttcagtgcac tcaagcgatc acggcaatat
    24961 ccgctgctct gtatcaccct gccggggaac catcacgagt tgtcatgggt ggtgatcggg
    25021 aaacgttgtt ggacttggtt gtgggtggtg ggtgagggtg ggtgggtgac tgactcgccg
    25081 caggtttggg tgctgggggc gcgtggggct ttgggggtgg gggtggggcc tgggcggttg
    25141 cgggcggcgt tcggggcgtt tcccagtggg gttgtggcgg tggtggctcg ggtcgggggg
    25201 cgggtggtgg ggttggtggc cagttcgttc acctccgtgt cgttcgagcc gccgttggtg
    25261 tcgttctcga tcagacctcg gggcctggcg gtgcggtgac gctcaccgag ggggtggcct
    25321 ggttcgacac gacgatcgag cggcacatcg aggctgggga tcacacgatc gtcctcttgc
    25381 gactgcacgc ggtggcgcac gtggagcacc cgctgccgtt ggtcttccac cggagtcggt
    25441 tcggtctcaa ccggtgacgc gggtgaccct ggccgaggtt atgccgggga tcgaggtggc
    25501 caggacctcg gcgacgtggt ggtcggtggg gtcgtcgtgg gtgtcggtga tcgtggcggt
    25561 gccgtcggtc acgtcgatgg tccagcgggc ggggtcgccg tagagggtca ggcggtggcg
    25621 cagagcggtg gcgagggccc tgtcgtcgcg ggtcagcagg tggagcaggt cggcgcgggt
    25681 tgtgatgccc accaggcgat cgccggtgac gatgggcagg gcgcgcaggg cgttgtcgcg
    25741 catcgtggtg accaggtcgg cgatgtcggt gcccgcggcg gcgcggggag ccggggtggt
    25801 catgatcccg gcgacggtgt tcgggggtgg taccgcggcg gggtgcaggt ggcggaagcg
    25861 gggatcgcgg gggaagcggt cgcggacgat gtcagcctcg gtgacgacgc cgaggagtcc
    25921 gccgtcggcg gaaaccaccg gcagggtggt gaaaccgtgg gaatccagca gttcggcggc
    25981 gtgcttcacg gtcgtcgtcg gggtcaccgt gaccaccggg ctggtcatga cgtcgcgggc
    26041 gcgcatggcg gacctcctcg ttcggcgtga tccccaggct aggcgtcctg gcctgcccgg
    26101 cagcaccacc gttggtcccg ggattggcgt ccacatcgga cccggcgcac gggaccaagg
    26161 tcccgcggtc acagggccag cggccggtac cgcgcggtgg tcgggcgcgg cagggtggtg
    26221 gtgacacggg agggaagtca tgtccaccac cgtttcgacc gtgcacgccg ccatctcggc
    26281 cgccgtgcgg gcgccgtcgc cgttcaacac ccagccctgg ctgttcgccg ctcacccgga
    26341 ccgggtggac ctgtggctcg accggtcccg ggtgatgacc gtgaccgatc ccgacgcgca
    26401 cgaggcccgg gtcggttgcg gtgccgcgct gcacacgctg cggctggccc tggccgtgtc
    26461 cggccaccgc accgaggttc acgtgctgcc cgacagaacc cggccggacc tgctggccac
    26521 cgtgctgctc gacgggaagt accggccgac gccgcacgaa cgcgcactct cggaagccgt
    26581 gtggcgcagg cacaccaacc gcagaccttt cctggaccga ccggtcccgt ctccggcgaa
    26641 gacggcgttg atgcgcgcgg cgacggtcga gggtgcgcag ctgcacctga tggaccagcc
    26701 cgccgaggtg ggcgcggtcg cggacctggt tcggcgcgcc gaccacgtgc tcagccagga
    26761 ctcggcgcac gtcgacgaag tacacgcctg gatcggccgc cagggccggt cggacggtgt
    26821 cccggtcgcc gcgtccggcc gtccctccac accggacaca ctcatcgtgt tgcgggagct
    26881 gggttcgccc gctcccgccg ttccgttcga gcgcctgcca ctgctcggcg tcctcaccac
    26941 ggtcggcgac acccacagcg accacctcgc ggcaggtcaa gcgctccagg cggtcttgtt
    27001 gcaggcgtgc gcggccggac tcgccgtatc gccgttgtcc caaccgatcg aggtgcccgc
    27061 gacccgggac gccctcagcg cgcacgtcgg cgcggcggcg cacctggtgc tgcggatcgg
    27121 gtacggccac tcgggcacga cgaccccgcg gcgcccggtc tcggaggtcg tcctggactg
    27181 aacgggtgac gagccgcggc attccggtga tggcccgctg atcaccggtc gcgcccgcac
    27241 cgccgttcct agcgtgcgat gcagcgcgaa cggggaggtc ggggtgggca aggcactttc
    27301 gttgtcgatg gccgtcgttg tcgggttggt cagcgtgacg ccatcggccg cggcggaggc
    27361 gagcagcggc tacgtggtcg tcctgaagga cggtcgggca cccgcggccg aatacgccgt
    27421 gcggcagacc ttccggcacg ctgtgaacgg gttctccacg gacctgacgc cccggcaggc
    27481 gcaagcgttg gcggctgacc cggcggtggc gtacgtccag ccgaacaggc gggtccgcgc
    27541 ggacacgacg cagacctacc cgccgtcctg ggggctggac cggatcgacc agcgcgacgg
    27601 cgacctcgac gacgcctaca cctattcgac caccgcgtcg aacgtcaccg cctacgtgat
    27661 cgacaccggc gtctacaccg cgaacaccga cttcggcggc cgcgcgacct ggggcacgaa
    27721 cacctcgggt gacggcaagg acgccgactg ccacggccac gggacccacg tcgcgggcac
    27781 catcggcggg gcgcgccacg gtgtcgccaa ggggatcaac gttgtcgcgg tgaaggtcct
    27841 cgactgcaac gggaacggaa cgaccgagac cgttgcggcg ggcatcgact gggtgatcgc
    27901 gcaccacacc tcagggcccg ccgtggcgaa cctcagcctc ggcggcgagg cggacccggt
    27961 gctcgacgcg gcgatccggc ggttgatcgc ggacgggatc accacgacgg tgtcggcggg
    28021 caacagcggc gccgacgcgt gccagcaatc cccggccagg acggcggagg cgatcaccgt
    28081 cgggtcgacc agcgagggcg acgaccggtc gtcgttctcc aacaccggca cctgcgtcga
    28141 cctgttcgca cccggcgaga gcatcacgtc ggcctggaag agctacccgg actcgaccaa
    28201 caccctgagc gggacgtcga tggccgcacc gcacgtggcg ggcgccgccg cactgttgct
    28261 cgcggtcgac cctgccacga caccggcgca ggtcgccgcg cacctggtgc tcgacgccac
    28321 gccgggcaag atcaccgatg tcgggccggg ctcccccaac cggctggtgg tcgtcggcac
    28381 cgggagcagg cccgggtacc cgatcgtggc caaccccggc taccgcgcgc aacgcaccgg
    28441 cacgccgatg accatccagg tggcggcgag cggcggcacc gccccgtaca cctggtcggc
    28501 ggccgggctg cccaccggga cgagcatcgg cgcgagcacc ggtctgatct ccgggacgcc
    28561 cacgcagacg ctggtgaaca gcccggtgac cgtctcggcc aaggacagcg cgaaccgcac
    28621 cacgacggtc cggttcctgg tcacggttgt cccaccgggg tggacctgcc cgtccggcgg
    28681 ccagaagctg gccaaccccg gcttcgagag cggtgacacg gtgtggtgga ccagcgggta
    28741 ctacgtcgac cggtggacgg gcgtcaacgc gccgcgcacc gggagctggg cggtgaagat
    28801 ccccacgacg acctccatgg gaaaccacgc ggtccccgag gacgtccgca tcccgcagga
    28861 gtgcgcgtgg tcgacactca ccttctgggt gaaggtcacc catcagggcg cgaaggacga
    28921 ctgggacaag ctccacgtgc gcatcgatgg caagacactc gcaacggtgc tgggcaagac
    28981 cgcgcccgcc gggtaccagc agtacacagt ggacctgtcg ggccacgcgg gcaagacggt
    29041 ccggatctgg ttcaccacct ggggcgacac ggcgaacatc accgacttcg tgctcgacga
    29101 cgtcgcggtg accctccgct gaccgcaccg ctacgatcgc gcggtgacta ccgacctgtt
    29161 cgggggcctg gacgcctcga ccctgcccga gcggcagcag cgcatcctgc tcgcgatcca
    29221 ggactgggtg gtccgccacg gctactcccc cagcacccgc gagatcggcg acgcggtggg
    29281 gctgcggtcg gcctcggcgg tgtcgcggca cctggcgagc ctggaggaca agggtttcct
    29341 gcgccggggt gcgtcggtct cgcggccgat cgacgtgcgc gacttcctcg gcacccagga
    29401 gtcggtgccc gcggactcgg tgggcgtccc gatcgtcggc gacatcgcgg caggcgcgcc
    29461 gatcaccgcc gaccagcacg tcgacgacgt cctgaccctg tcgcgcgagc tgaccggccg
    29521 gggcaccgtg ttcgccctgc gggtgcgcgg cgactcgatg gtggacgcgg ccatctgcga
    29581 cggcgacatc gtcgtggtgc gccagggccc cgaggcgcac tcgggccagg tcgtcgccgc
    29641 gatgatcgac gaggaggcaa cggtgaaggt ctaccgccac cgcaacgggc acgtgtacct
    29701 cgaaccgcgc aacgatgcct acgacgtgat cgacggcgac aacgctgtca tcctcggcac
    29761 cgtggtgtcg gtcctgcgca ccatctgaca ccggacctcc gctccgcgaa caccgccgaa
    29821 ccggacagcg gagtggtcgc ctacccacgg gctccgcctg ccctgccaac gtcgtccgga
    29881 gcacgctcct agtcgcggat catcaaccct ttccgcacga gggaagacag actccatggg
    29941 acgacccact cggcgtagac ggtcacggtg tcggtaggcc cgtttccgat agatacctac
    30001 ccgcacacaa aggcggcgcc gcagagcgcg tccgacaact acctcggcga cctggagatc
    30061 acgccggtgg gcgactgacg gtgagggtgt cggggaaggt cctggcgacc tcgtggcggg
    30121 agtcgaggtg gagtttgcgc aggacgttgg cgacgtgctg ttcgactgtg cggcgggaga
    30181 ggaagaggac gtcggcgatg tcctggttgg agcggtgttg ggccaggagg cggacgacgt
    30241 cgcgttcgcg gggggagagt tggtcgccgt agctgcggcg acctcggcgg aggtggggga
    30301 tggagccgtt gtcgcgcagg aggtggcggc agcggttggc gtcgagggtc gcgcccaggt
    30361 gttccagggt gtcgacgacg gtgagcaggt cggcggtggc ggcggtgcgg tgggtgcgca
    30421 ggcggcagcg ggcggtggac tcggcgtggc gggtcgcggt gtacctgggg ctgccttggc
    30481 gggccaaggt gtagtgcgcg gccgcggttt ccacatcacc gtcggcctct gctaccaggc
    30541 cacgacactc atcggccact atggacggta ggttcatcga cgccgtgcac cgcagcagct
    30601 cggcgacgag gcgacgcgcg tcgtccagtc gacccagcct gcagagcgcg gcgaccgccg
    30661 cgggcacgac ctcgcctgcc cacgcccagt tccccttgtc ccgcaacaac cccaagccca
    30721 gcttgacggc gtcctcgacc tcctccgacc ggtcgcggtg cagccacatg cggatggctg
    30781 tggcgtgcgc ggcgagcagc accggcacga tcgcgtccgc cgagatcgcg gccaggttcc
    30841 gctcagcccc cgcccagtcg cccgtcgcca acgccagcca ggccaggacc agcgccccct
    30901 cggccgaccg ggacgccgcc gcccgctccg ccaggccggt ccactgtcca ctgtggaagt
    30961 cgagtaccaa cgcggccggg cctggcgcgc ggcgcaggtg ggcacgcgcc aggtcacggt
    31021 ggccgatcca gcacgccgcc tcggcgatgg cgcggtggtc ggccgtgtcc gcgtgggcgg
    31081 gcaccatcgc gagcatgtcc caggcgaccg ggtccgcggt gtgcagccgg ttggtcgcca
    31141 cggccgcgag cagcgtcgtc cgccctggac cctccgggta ccgcgccagc acccgctcgc
    31201 tccggtccat ccactccagg ttctccgcca gcggccgcga cccgagcgtg ggcgcggcca
    31261 gcacgaccat cccccgcgcg gcgacctccg gccgcaagcc cgcgacggcc cgccgcacct
    31321 cccccacacc ctcgtagacc ccggcgcgca ccaacaacaa tccccgaccg agccgcacct
    31381 cggcgcgcgc cgactcggtc aaccgggcgt cgccgaccag cttggtcaac accggtagac
    31441 caccaacgcc gacaacgccc gcgtaccgca ccgccaggcg gcacaggtca gcggcagaca
    31501 gtgctggctc cgctagcaac ggctcgatcg cctcgaccac aacagaagca cccgcagcag
    31561 aatcacgcgc aggtgcagtg gaatcctgcg tggccgtgat gaccgcctcc acctgctcga
    31621 cccactcccc caaccgtcca gccaaccggg cgtgctccgc caacacccgc ggcgccaccc
    31681 ccggcatccc gcgcaacgcc cgcagcgcgc gccggtgcga ctccacccgc tccggcccgg
    31741 tcaactcgtc gtacacgacc cgccggaaca ccccgttggc cactcggaag gcgtccggcg
    31801 cgtgctccac gagcaccccg gtccgcagcg cggccaccac ggcgtcgcga ccgcccgaca
    31861 ccccaccgat ccgcgccagg acctgcgtcg acaccggcac gtccaccacg gcagcggcga
    31921 cgaccaccgc ccgcgtgtcc gcgcacgccc cctccaaccg agtggcgaca tcgtcgtacg
    31981 ccgccgcggg tacagagaac cctgccgcca ccagataggg cacgccaccg gtatgcgcca
    32041 gcagcgcgtc ggcgtcgggg accagcggat ccaggtcctc acgggtgaac ggcccgagat
    32101 ccacccgcgt gccgggaaca cccaacgagc cgcaccccgg ccggtacgtg agcacgaccg
    32161 cgacccgatt cgcaacggtg ctgatgagga accgcagcaa cgccctggtg tcctcgtcgg
    32221 cccagtgcgc gtcctcgacg accaggacca ccggcgccag cgcgacgagc aactcccgca
    32281 ccgcgcggaa caccaggtgc cgcccggccg cctcgtcgac gcgatccggc acgggcggca
    32341 gcaactccgc gacctccggg agcaccgagc gcaacgcgcc caccaccggg ttcaaccgca
    32401 ccgcgccgat ctcggccacc gcgacccgca gcccgtcgac caccggcccg tacgcgaacg
    32461 tccccaccga cggcggctgg cacaccccgc gcaccacgcg ccggtcccgc accgccgggt
    32521 cggccagcag ctcgtcgacg aaccgggact tgccgtgccc ggtgtccccc acgacgtgca
    32581 gcggcgcacc cgccacgcgg acggccccga ccgcggcggc gagctccgcg cgacgctgca
    32641 ccaggacacc ggtcaccgca ttcccctttc gcgatttcgt gcctttccca gcctacgtag
    32701 gtagcgccac cggacctggc gcggcgaata aatgggtatc tccacttaat ggcgtgcgga
    32761 ttggcttacc ggcccgttcg gggaaggttg ggcgctagtg gtcgcccgtt ccaaccctgc
    32821 tcgcgaccac tcgccgcagt ggcgtcgccc gcggtgcagt gaatgggagt ttcgatgaat
    32881 tacaggtatt cgatgcggtc gttggccgtg gcgggcgtgg tggcgggcgc ggcgctcgtc
    32941 gccgcggtgg cccccgccat cgccgccccg gccgaaggca ccatccgcag cgcgggcgtc
    33001 cccggctccg tcgctggcag ctacatcgtc gtgctcaagg acaccgcagg cgcccaggcc
    33061 gtcaactcgg tctcggccga cctgacgagc aagtacggcg gtcagcgcaa gctgacctac
    33121 tcggcggcgc tgagcggttt ctcggtctcg atgtccgagc agcaggcccg caggctggcg
    33181 gccgacccga aggtcgccta cgtcgagcag gacggcaccg cgcacggctt cggcgagcag
    33241 ccgaacccga cctggggcct ggaccggatc gaccagcgct cgctgcccgc cgacaacaag
    33301 tacgcctacc ccaacgacgg cgagggcgcg accgtctacg tcgtcgacac cggcgtctac
    33361 cgcggccact cggacttcgg cggccgcgtc acctccgggc gcgacttcat cgacaacgac
    33421 gccgacgcct cggactgcca cggccacggc acgcacgtcg cgggcaccgt cggcagcgcc
    33481 acctacggcg tggccaagaa ggtcaagatc gtcgccgtcc gggtgctgga ctgccagagc
    33541 tcgggccagt ggtcgcagat catcggcggg ttcgactggg tcgcggccaa cgcgggcgcg
    33601 aactcggtga tgaccgccag cctcggcggc agctccaact cctcggtgga cgacgcggtg
    33661 gccaaggtcg tgcagaaggg catcacctcg accatcgccg cgggcaacaa caacggcgac
    33721 gcctgccaga ccagcccggc ccgcaccccc agcgcgatca ccgtcggcgc gtccgacaac
    33781 gccgacaagc gctcgctgtg gaccaacggc cagggctcga actacggcac ctgcgtcgac
    33841 ctgttcgccc ccggcaccaa catcctctcg acgctgcaga acggctcgtc cgggacgatg
    33901 tcgggcacct cgatggccac cccgcacgtg gcgggcgccg cggcgctgta cctgaccgcc
    33961 aagccgggca gcaccccgtc gcaggtcagc agcgcgctgg tcgccgcggc caccccggac
    34021 aagatcagcg acccgaaggg ctcgccgaac aagctgctct acgtcaagga gctcggtggc
    34081 ggcacgccgc cgaacccggg cacctgcgcc ccgcagacca gctccggcgc cgtcgccatc
    34141 cccgacgcga gctccgctga ctccccggtg accatggcca actgcaccgg caccgcgtcg
    34201 gcgtcgacca ccgtgaaggt cgacatcgac cacaccttca ccgccgacct cgccgtcgac
    34261 ctggtcggcc cgtccggcgc ggtgttcagc ctgcggccct ccggcggcct cggcgacgcg
    34321 aacggcatcc acaccaccta caccgtcaac gcctcgggcg agcagaagaa cgggacctgg
    34381 aagctgcggg tcaccgacgt ctaccgcttc gacaccggct ccatcacctc gtggacgttg
    34441 accccgtgac cgcgcctgac ctggagaaga agacgatgtt gagatccaag cgctccgtgc
    34501 gcgtcggcgc ggtggcggtg ggtgtcgcgg tgagcgcgct cgcggtcgtc gcggtcgcca
    34561 gcgccgcccc ggccaacgcc aaggcggcca acttcgaggg cgacaccccg gtgccggccc
    34621 ccgacgccac cgcccagatc tacaagggcg tcgacgccac cctctcggac tacccggccg
    34681 tcatcggcgc cctgcgcgag ggcgggtcgc ggcccaaggg ccagtcctgc accggctcgg
    34741 tcgtcggcaa gcgcagcatc ctggtcgccg cgcactgcta cgacctggcg ggcaccaa
//
