LOCUS       NZ_RCDD01000001        24106 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Actinokineospora cianjurensis strain DSM 45657 Ga0180969_101, whole
            genome shotgun sequence.
ACCESSION   NZ_RCDD01000001
VERSION     NZ_RCDD01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Actinokineospora cianjurensis
  ORGANISM  Actinokineospora cianjurensis
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Actinokineospora.
REFERENCE   1  (bases 1 to 3297612)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 3297612)
  AUTHORS   Goeker,M.
  TITLE     Genomic Encyclopedia of Archaeal and Bacterial Type Strains, Phase
            II (KMG-II): from individual species to whole genera
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 3297612)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
REFERENCE   4  (bases 1 to 3297612)
  AUTHORS   Goeker,M., Huntemann,M., Clum,A., Pillay,M., Palaniappan,K.,
            Varghese,N., Mikhailova,N., Stamatis,D., Reddy,T., Daum,C.,
            Shapiro,N., Ivanova,N., Kyrpides,N. and Woyke,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2018) Prokaryotic Super Group, DOE Joint Genome
            Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.9.0
            Genome Representation             :: Full
            Expected Final Version            :: No
            Genome Coverage                   :: 102.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003663795.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:08:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,669
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,552
            CDSs (with protein)               :: 6,552
            Genes (RNA)                       :: 63
            rRNAs                             :: 4, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 3, 1 (5S, 23S)
            tRNAs                             :: 53
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 10 of 54
            Pseudo Genes (incomplete)         :: 50 of 54
            Pseudo Genes (internal stop)      :: 2 of 54
            Pseudo Genes (multiple problems)  :: 7 of 54
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:04:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2745169
            Orig. end                         :: 2769275
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RCDD01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24106
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="10"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24106
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24106
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14106](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14106
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(760..1056)
                     /locus_tag="CLV68_RS12280"
                     /old_locus_tag="CLV68_2442"
     CDS             complement(760..1056)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_2442"
                     /product="hypothetical protein"
                     /protein_id="WP_121390467.1"
                     /transl_table=11
                     /translation="MTSRIELDLPYPGDTLPLGDLERFVDHARQAGADSATPLIVVGAD
                     QDDSMTIGLRIEFESTRQDLIRLLDEIDSNDGDPHAQRRATRELREHLTKSTG"
     gene            complement(1227..1472)
                     /locus_tag="CLV68_RS12285"
                     /old_locus_tag="CLV68_2443"
     CDS             complement(1227..1472)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_2443"
                     /product="hypothetical protein"
                     /protein_id="WP_121390468.1"
                     /transl_table=11
                     /translation="MSILGTHIATHWIIPLLGTFLLLRSLVGMLADQGTSFRIKIGITG
                     VQIDWNKIKTEDVQDTDTSCNELSRTNDDCTPTRSN"
     gene            complement(1469..2578)
                     /locus_tag="CLV68_RS12290"
                     /old_locus_tag="CLV68_2444"
     CDS             complement(1469..2578)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_2444"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_211346480.1"
                     /transl_table=11
                     /translation="MSPAPLYRRMLRAREPEAPEFVTLPISGGSSELTLAMTGQIAKWN
                     MQWEAAQFRRRVIAEADLSPRMLAIAEQGDINVVFIPRTRSRYHEYAPLFHLLPRTVVE
                     RHGLPLLHGGQWPFVAEHTPVDPYLPVNFSEALSRAWASVVWRDLVSGSSMAAFTRDDP
                     MRLLAHNLDFWLPAVTSVVQALLSEFPQVGDAVAPESPRLADGSPLTGTYWGVPRQGGD
                     VWLGEADAADVRDMVVDEADASGKLREIIDAIKSNRVADDFSDRWSYAKEDFERKIHHK
                     RLKIKVTFVELPDGVPVHGPETEVIDRVLVGDFMTLLKPKDRELIILLRSGMTSLTDIA
                     DQMGYANHSAVSKRLDRIRKRAASFFEAS"
     gene            complement(3379..4791)
                     /locus_tag="CLV68_RS33345"
                     /old_locus_tag="CLV68_2445"
     CDS             complement(3379..4791)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS33345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_2445"
                     /product="hypothetical protein"
                     /protein_id="WP_147459959.1"
                     /transl_table=11
                     /translation="MASTNPHEIVTGVKQAVTEEVASLTPDAKIVATEYFNHSYMPDLV
                     VEWREAGKSDSRPIFIRNTLRPSTAAEVQALAAREPMMVSLDSRIEPPSALRRQAQEAR
                     RVLVTDLASLAEVAAPASSEGSTNLGGPGEPLVRLIQTNLVKGGRGLLTADDAGRLIRS
                     ATPETEDSNFNADFLHSFQESTEEVFTEDAALRLQRAAELLHLGISPEDVRHSETAFGG
                     ELSDVELRVLLPYLLNNLNAVTKPDLWIRIGSMMSLERLEDMTDILEDVDVSPLVVANA
                     QIWRARRAQLVIDNESEALDGDQEEHPAAQDETDSETSTWRVRNRMLIANVGRWRVLVT
                     TDARRLRGRDGSLAARWDDIAELLSGFALDAVDLRGVSRRILVSAEQSGDVRGDVRLIR
                     DSIEDSFHVTEVHVRRIGDDTADSVMRTDFADMTVSATNGAPISSIVSALHLLAHRWPA
                     DFTSLIDRSAPA"
     misc_feature    4800..4814
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(4833..5411)
                     /locus_tag="CLV68_RS12300"
                     /old_locus_tag="CLV68_2446"
     CDS             complement(4833..5411)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_2446"
                     /product="hypothetical protein"
                     /protein_id="WP_121390471.1"
                     /transl_table=11
                     /translation="MSAAESVQQDGIDGVDFAKRWLESTTWIDLPFDAYNNAPICTLTR
                     LDNKMKRYDLFGSIHTSPPSPVYVEVKNYTSTGGKQGEEYWEFLANAYSITARDIKNGE
                     DGRREFMWITRHPFNQTDWTALTSAGRINAALGKHPEVLDGQAIDIDLLSTVADRLWLL
                     VVHQRQEGLMLSAEELSIVESRLNRKGKK"
     gene            5707..6801
                     /locus_tag="CLV68_RS12305"
                     /old_locus_tag="CLV68_2447"
     CDS             5707..6801
                     /GO_function="GO:0004527 - exonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020497182.1"
                     /locus_tag="CLV68_RS12305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2447"
                     /product="exonuclease domain-containing protein"
                     /protein_id="WP_121390472.1"
                     /transl_table=11
                     /translation="MNNPVTSWASGPMIALDLETTDVDPHRDRIVTASIVIITPGLPGE
                     TTEVTTLNWLANPGVDIPVEATRLHGVTTEQAQHDGRPAADVVAEVAADLAQLWTPTTP
                     LCAFNASYDLTMLDAELRRYHGRGLPLGGSVIDPLCIDRHLRPVSGWDDRRTLANVCAH
                     YEARLDAAHSSAEDAIATARLAWLLAKRHPQAVGLLDLHELHKRQAGWFQTQENTYANR
                     QERKLKQLVARGASSEKTDQMRERIAKIRASAKYWPLRPDLGDTAQPVRTRPAAPQPGE
                     PANARASWTPELDASLREEWLAADPGALAETLRKELATQFRRTPGAIRSRLLKIRCDPE
                     LPSSTCDEQRAAELQRVYDAEYGR"
     misc_feature    complement(5708..5725)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.2"
                     /tool="antismash"
     gene            7023..7916
                     /gene="mmuM"
                     /locus_tag="CLV68_RS12310"
                     /old_locus_tag="CLV68_2448"
     CDS             7023..7916
                     /EC_number="2.1.1.10"
                     /GO_function="GO:0047150 - betaine-homocysteine
                     S-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="mmuM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007025219.1"
                     /locus_tag="CLV68_RS12310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2448"
                     /product="homocysteine S-methyltransferase"
                     /protein_id="WP_121390473.1"
                     /transl_table=11
                     /translation="MDLSDAISIRTLDGGLSTELQARGHDLSDHLWSARLLIDDPAVIV
                     AAHVAFYRAGASVATTATYQASFDGFARRGVDYGQAELMFRRGVELAQQARAELAEDGH
                     QRWVAASIGPYGAALADGSEYRGRYGLSVGELTDWHRPRLSVLADAGADVLACETVPDV
                     DEAEALVAVLGEIGTAAWLSYTVEGGRTRAGQPLDEAFGLVAASREVIAVGVNCCSPVE
                     VGPAIEVARAVTDKPVIVYPNSGEQWDGKWSGSSAFTAGMAREWVAAGATAVGGCCRVT
                     PQQIAELAAVLDETKS"
     gene            complement(7913..9202)
                     /locus_tag="CLV68_RS12315"
                     /old_locus_tag="CLV68_2449"
     CDS             complement(7913..9202)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024949.4"
                     /locus_tag="CLV68_RS12315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2449"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_170224244.1"
                     /transl_table=11
                     /translation="MTGRREDVGARWHSLGASLARWRKASPLTQSDLGRLTHYSRTSIS
                     HIEAGRQSAPRSFWEAADQAYEAGGALLTEYDRAYTYQERARIIELEQAQEDRKAQIAN
                     GSPFGGAPALLHPNITALPHPLSTKVRVDSDYIERLHGEIKGFVRLDQQYGGAVTSPLI
                     VQAFKQARHRVKTSEIQKGLARDADAATAELAEVAGWSLYDAERHQQAHEMNVEALKLA
                     RRAGDRSMELFIMQNMSMHASHLGHAQEALDIARSALDAKLTPRLQSLFRLREARALAE
                     LGADGDSRKTFRLARDLHADGVSDRDPHWAWWVDDAEFAWHEGKIQLDLGERGRALDFF
                     DLAANGISEHRVRTFYSYRASAFVAHVINKSWPDAERSMKVLLGHIGLVGSRRGDRTVE
                     HGLDLLDRTAAPGTITDLARALRKALALTI"
     misc_feature    complement(9240..9260)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.36"
                     /tool="antismash"
     misc_feature    9488..9501
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
     gene            9809..9943
                     /locus_tag="CLV68_RS12320"
                     /old_locus_tag="CLV68_2450"
     CDS             9809..9943
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="CLV68_RS12320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2450"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_121390475.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 4.3e-14, bitscore:
                     49.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIATLDEFALDVQIVSDSPAGEPAACATDDGCASTCASSCVSNV"
     gene            10001..12985
                     /locus_tag="CLV68_RS12325"
                     /old_locus_tag="CLV68_2451"
     CDS             10001..12985
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="CLV68_RS12325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2451"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_121390476.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 7.9e-178,
                     bitscore: 589.9, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 7.2e-18,
                     bitscore: 62.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.5e-18, bitscore:
                     64.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTDSKLLYRHTGAALLRAAARPLDETQDDWPDLGDTESCRTWLK
                     RTWSRSTFADAVRIASPTFAERLDSLDSLRPKEVRRAAATAVRYALRACTRHTPFGLFA
                     GVASAEIGSPGMSRWGQGHHEVARVDSQWLAGVIARLEAEPILLERLKVMFTNLAVERG
                     SRLEAPCGPETVSIRLTGPVAFTQASASTPILFAELVDLLLAKYPNADRATITRMVSEL
                     VRQQVLITSLRAPLTVVDPLGHLLDQLHAAGAEYVAGLEALVDELCAVDVLIRRHNRHA
                     LGDNQNRAVRIEIGRRMREVSTGGRTPLAIDLRLDCDVRVPEQVVRDVEGAATALARLT
                     AQPTGEPAWRDYYTVFCDRYGTGTLVPLTEVVHPDSGLGFPSGYPGSVRPSSFRTGSDR
                     DQTLLSLAWTALADQRREVVLDEPAIESLMVSEATQPRYPAHVEVAARIHATDINALDQ
                     GDYLLTITPGRSLGTFTSRFATIAPGTDLRRIYASVPTVARQAVPAQLSFPPVYAHAEN
                     VCRVPEYLPDVLSLGEHRADATMALDDLAVTATRDGFHLVSLTSQRIIEPQAFHGLALQ
                     KQSPPLARFLAHLSRGLQASWHKFDWGSHANQMPYLPRIRHGRAILSPARWRLASADAP
                     SLESWRKRWDVPDLVELAADDRSLRLNLNESTHVALLVAHMERTGDATLVETINDPGEL
                     GWIGGFAHEIVFPLTSTQAPASAPTGRTARRISCRTHGVVPGAPTAAWLNAKLHTHPQR
                     INEIITDRLPTLLDPLGGPPFWFVRYRSATETDHLRLRLPADGTDVHVALGRWAEALRR
                     DGAISRLVLDTYFPEVGRYGAGEAMAAAENVFVADSQATAAQLRYLPEQREAMVVVNMV
                     ATVCALLGGEVAIQWLVDHPAPPGPAIDRPLFDQVLALLRGPATSPPDGWNQTLIQTWE
                     RRAEALAAYRSHLTDDNQVATAVESLLHMHHNRLIGIDRDYEIRCRRLVRQVALTWAHR
                     RGGSR"
     aSDomain        10457..10705
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CLV68_RS12325_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="7.00E-20"
                     /identifier="RREFam001.1"
                     /label="CLV68_RS12325"
                     /locus_tag="CLV68_RS12325"
                     /protein_end="235"
                     /protein_start="152"
                     /score="62.5"
                     /tool="antismash"
                     /translation="VMFTNLAVERGSRLEAPCGPETVSIRLTGPVAFTQASASTPILFA
                     ELVDLLLAKYPNADRATITRMVSELVRQQVLITSLRAP"
     misc_feature    10496..10498
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11210..11212
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12982..14106
                     /locus_tag="CLV68_RS12330"
                     /old_locus_tag="CLV68_2452"
     CDS             12982..14106
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="CLV68_RS12330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2452"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_121390477.1"
                     /sec_met_domain="LANC_like (E-value: 5.7e-41, bitscore:
                     137.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPTDSLADGAAGIALLHFERARTGACATIDAHPWAVTMTKGPVT
                     AHPDVASLYRGAPAVAFALLTAGHPAYAAAVADLDEHIVTLTRERLERAHRRIDNSLLP
                     DIREFDLISGLTGIGTYLLHRGHHLLTEVLAYLVRLTEPLGELPGWWCGPPTDGLAEEW
                     IGGHGNLGLAHGIAGPLALLAMAMRRGLVVDGQVEAISTIWRWFDDWRVGTGREAWWPG
                     RITGAELVTGTVTQAGPQRPSWCYGTPGQARALQLAALALGDTRRQQQVENTLAGCVTD
                     PSQLGLLVDTTLCHGWAGVVLTTWRAAADAGPDSELAAHLPRLRELLDHHLQTSTTPGH
                     GLLEGEAGQQLTCLAIDTDQPVRTTWDLCLLVSG"
     gene            14140..15342
                     /gene="fxlM"
                     /locus_tag="CLV68_RS12335"
                     /old_locus_tag="CLV68_2453"
     CDS             14140..15342
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Methyltransf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="CLV68_RS12335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2453"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_121390478.1"
                     /sec_met_domain="PCMT (E-value: 6.5e-44, bitscore: 147.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="Methyltransf_3 (E-value: 2.3e-06,
                     bitscore: 24.4, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTTTDSVPETLRACMVDTILAAGHAQTPAVEAVLRALPRHRFVP
                     EASLEDAYADIAVITKRAADGAALSCASVPTVVAMMLDQLDVHPGQRVLEIGAGTGYNA
                     ALLAELVGPDGAVTTVDIDEEVTAGARRGLDATGHDHVRVITRDGALGAPEHGPYDRII
                     VTVGAWDLPPAWHDQLVPGGRLVVPLRWRGQTQAVAFIREQDRLRSDRMNLCGFVPMIG
                     QDGEKNGTITTDGTVTLYYDIDQPIDPTALTGVLDQPRVSVWSGVTIGASEPFDGVWLT
                     LTATDPATCRIAAKQTAIDSGLCTPAIGSRSPALAEDVSLAYFTYRRLDAPEARFELGA
                     HAHGPIGEQLAERLCAQIRTWDNDRNHHPQIHARPANTQTVTLPAGQVITKRDSTLVLL
                     P"
     gene            complement(15415..16044)
                     /locus_tag="CLV68_RS12340"
                     /old_locus_tag="CLV68_2454"
     CDS             complement(15415..16044)
                     /EC_number="3.4.23.43"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004190 - aspartic-type endopeptidase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013632.4"
                     /locus_tag="CLV68_RS12340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2454"
                     /product="prepilin peptidase"
                     /protein_id="WP_170224246.1"
                     /transl_table=11
                     /translation="MDSWIFIGVWALVGTLSATPANALVRSLALPTSSSVDYRLVMACG
                     SVTYALLAARLGMGATLVAYSVLASLIIPLAAIDIREHRLPTKPIIAAAAAITILFAAA
                     TVLSRQPEPLIRGVICSAVCLVLLTIAYLISPGFIGGGDIRLAALLVLALGWTSWSAAI
                     RAIVIGLFIGALHGASCLIGRRSSERRDVPLGPALAAGALFSILIV"
     gene            16327..16881
                     /locus_tag="CLV68_RS35070"
                     /old_locus_tag="CLV68_2455"
     CDS             16327..16881
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS35070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_2455"
                     /product="hypothetical protein"
                     /protein_id="WP_246009779.1"
                     /transl_table=11
                     /translation="MSPKTIAAVTMAVVVLAAGCGGSSADPPPTSAGLPTSSPPSTAVA
                     TTTESADERDGRAASDAYLGMWRAMAQAGLTSDWQSVELAKYAKGEALSTITRSLYRDH
                     TNQVVTKGEPKNNPQVTSVESNTVTIADCGDSTNWLKYKTTGELKDDTPGGRRAITAEA
                     TRQDDGSWRVTSFVVQAVGTC"
     gene            complement(17126..17647)
                     /locus_tag="CLV68_RS33830"
     CDS             complement(17126..17647)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS33830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_170224248.1"
                     /transl_table=11
                     /translation="MVDVVNSGNVPPVPAPAHDTDQWIVAVTGYRSLARRKVCPHVGDA
                     ARGSPPSNGSPGPLHVTVVPSPIDQVTAVGRAVAVTDTPGTDAVTDTGTHAPRSTHNQV
                     GRFTSWFCAGLAKIDGRGNDNRFRAVSANTRGDTGAGAASATQNGPSWKSGKHVSRYQP
                     PPVVGCPGSE"
     gene            17793..18500
                     /locus_tag="CLV68_RS12355"
                     /old_locus_tag="CLV68_2457"
     CDS             17793..18500
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CLV68_RS12355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CLV68_2457"
                     /product="flagellar biosynthesis protein FlgA"
                     /protein_id="WP_147459960.1"
                     /transl_table=11
                     /translation="MATVTSRSAADERSGPRGWSSTKRAGRAATGSRVNGAVQRRRAPY
                     LLLGVLLVVVCAGAGVYVATQAGNRVTVLALARAVTVGQVLAGQDLRQVSISVDSGLDV
                     VTAAESTAVVGTTMAYPAPAGTLLSRGLLGAALVPDAGSAITAVGLKDGQFPPSLTPGT
                     HVLVLISPPASTATSTASVAPPRTVRAVVTDVQARQSEQTTVVSLELPEASARELAGAS
                     AAQVSVVAVGGGR"
     gene            18500..19279
                     /locus_tag="CLV68_RS12360"
                     /old_locus_tag="CLV68_2458"
     CDS             18500..19279
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009151771.1"
                     /locus_tag="CLV68_RS12360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2458"
                     /product="chromosome partitioning protein"
                     /protein_id="WP_121391145.1"
                     /transl_table=11
                     /translation="MLVVVCSVKGSPGATTLSVALGARWTGPEEPVVVEADPGGGDLLA
                     RWRLEENPGLKSLAAAARRDSDPGLLAQHTQVLPGGLRVVAGPVGAEQARSALAVLAGG
                     SSSVVRAAAEVAGQVVICDVGRIDAQSPALPLLRTAEVTVLLARARDDELAHVAQKLDT
                     VAKWTPHPALVLVGEGYPTREVERELGVDVLARLPHDPRGAAVLGGQPGRRSPSRSALG
                     KAAASLADLLRAQAPTPQDNLPADLPAADVHLNGTRP"
     gene            19276..20661
                     /locus_tag="CLV68_RS12365"
                     /old_locus_tag="CLV68_2459"
     CDS             19276..20661
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156822.1"
                     /locus_tag="CLV68_RS12365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2459"
                     /product="ATPase, T2SS/T4P/T4SS family"
                     /protein_id="WP_121390481.1"
                     /transl_table=11
                     /translation="MTETTTFTRVAAAQTGVESGSEVEAIGRMRESLRLAVAAQLGDRV
                     SADDAAGRTPMTPPERRALAAVLVQEAADAYANGELERGGTLLSPEVEARVTAAVLDDL
                     VGMGGLQPLLEDESIENINVNGDRVFVRYADGRRTRLAPVVPTDNDLIDLIRDLAARSG
                     MEERRFDRGSPIVNFRLPDGARVSAVMSVTERPSVSIRRHRYSTVTLAELREMGTLDVA
                     LESFFAAAVRARRNILVAGGTAIGKTTMLRGLASAIPPEERLITIEDVAELGFGDDEQA
                     HPDVVALQAREANIEGQGAVSLADLVWQALRMSPDRVIVGEVRGREVIPLTNAMSQGND
                     GSMGTIHASSSKGVFTKLAAYAVQSPERLDIHQTNILIASALHLVVFLDKPRGEPHRRV
                     VSSIREVVNAEGSQVVSNEIWRPGSDRRAVPGAPIRTETMELLMDAGFEPDLLDNPDGW
                     WQP"
     gene            20658..21545
                     /locus_tag="CLV68_RS12370"
                     /old_locus_tag="CLV68_2460"
     CDS             20658..21545
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020638800.1"
                     /locus_tag="CLV68_RS12370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2460"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_121390482.1"
                     /transl_table=11
                     /translation="MTATTALLALLGVGVAAGLLLIAAGARGVEATDVPSKAQLWIAGL
                     RRHAHARLLAAAVLAGLVAGMVTGWLVGGVLTALAVAGLPQVLGGTRGHDRALARIEGI
                     ASWTEMLRDVIAAAAGLEQAILATAATAPEAIRAEIEDLATRLDRGDRLGPSLRLLADD
                     LADPTADLVLAALVLAADHQARQLAELLGELAAEAREQAAMRMRVEAGRARTRTSVRVI
                     LITTLAFAGGLVVFNRSYLEPYDAAFGQLMLLLVGALFAVSFVWLGRIARLRPAARVLT
                     GLTQLPTGATEVQP"
     gene            21542..22435
                     /locus_tag="CLV68_RS12375"
                     /old_locus_tag="CLV68_2461"
     CDS             21542..22435
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020663628.1"
                     /locus_tag="CLV68_RS12375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2461"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_121390483.1"
                     /transl_table=11
                     /translation="MITGLLLGVGFGIGLWSLVVWIAPPRQGLHAMLAAITAGPAPAPL
                     LTADSGGWGLRVGKPFVRPLASLGLPTPRVRRDLAVIGKSPQHHLAEMAVYGITGLVLP
                     TLAQALLLVADMPMPWQMPALVGLILGIVGLLVPDLTVRQEAARRRDAFRHSLGAYLNL
                     LRVLLAGGAGVDGALTDAVKVGNGWAFAQIRRALTTAAATRTTPWARLGQLGTELDVTE
                     LSELAASLSLAGTEGARVRASLAAKASGMRTRELTHAEGEAQSATERMSLPVLILFLGF
                     LIFLGFPAMSRVLIGL"
     gene            22454..22639
                     /locus_tag="CLV68_RS12380"
                     /old_locus_tag="CLV68_2462"
     CDS             22454..22639
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645825.1"
                     /locus_tag="CLV68_RS12380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2462"
                     /product="hypothetical protein"
                     /protein_id="WP_121390484.1"
                     /transl_table=11
                     /translation="MNVHLAVLVARIRANWQRLRKDENGYSTETVLVTALLVVLALAAL
                     AILAAKVTEKANGITM"
     gene            22648..23070
                     /locus_tag="CLV68_RS12385"
                     /old_locus_tag="CLV68_2463"
     CDS             22648..23070
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645824.1"
                     /locus_tag="CLV68_RS12385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2463"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_121391146.1"
                     /transl_table=11
                     /translation="MTTTPPHTLRARLRRLARDDRGAVSVELVMATPLLILLLLTVIQF
                     GLYLHACHVAQSAASQGLSAARVAGGTAESGSTETRRALDLLGGGVLGGTTVTSTRTTA
                     DASVAVTGVAVQVVPFLTLTVHAEAHGPAEVFRGAG"
     gene            23070..23510
                     /locus_tag="CLV68_RS12390"
                     /old_locus_tag="CLV68_2464"
     CDS             23070..23510
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020496977.1"
                     /locus_tag="CLV68_RS12390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2464"
                     /product="TadE family protein"
                     /protein_id="WP_121390485.1"
                     /transl_table=11
                     /translation="MLLQLKSRWQRLRVDERGSAAAELTVFTPVAVALLLFVVFCGRLA
                     ASEMRVTDAAHQAARSASISRTPGQADQNARTTAATALAQAGVTCQNLTVATDTQGLRP
                     GAAVTVTVSCTVGLSDLGLLGVPGNRTVSATYTSNIDTYRGT"
     gene            23513..23971
                     /locus_tag="CLV68_RS12395"
                     /old_locus_tag="CLV68_2465"
     CDS             23513..23971
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020663632.1"
                     /locus_tag="CLV68_RS12395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CLV68_2465"
                     /product="TadG family pilus assembly protein"
                     /protein_id="WP_121390486.1"
                     /transl_table=11
                     /translation="MPPPATLRRLAANAHRLRHDDRGRVTAFAVVMVNACLFVAGLVLD
                     GGIALTAKVDALGQAQEAARAGAQQVDLGAYRGGVLRLDVPRANQAAHDFLTAAGHSGT
                     VTVAGNRVTVTVTITRPTQLLGLLGVGTVTATATGTAEAERGVTRADP"
ORIGIN
        1 ccactttgat gatctccatt gctttccaga gctggtccca gccaatatgc tcggctcgac
       61 cgagcagcag gagaaggtcg tcgacgtcgg gatggtcggt ggcacgcttg agttgccgat
      121 atccgtcagg cgtggctggt tggctggatg tggctccgcc cacggtcatg accgggaagg
      181 cgctcatgcg cgcttcggca gtgcccacaa ccaccaccgt gaggtcgtcg cggagccttg
      241 cttgatcgcc agccatgagg tgggcgtcgg agccgccacc ttgcgggtga tcgcggtgga
      301 agcggtatcc gagtttgacc ggtcggtagc tggggtcgtc aagcgtggcc caaccgttca
      361 gccgagcaag gatgccggat gcgatctcga cgagttgtcc gccgtcggtg aagtccgcgc
      421 tgccgagggc ggacgcttcg agaaaggttc ccccgtcggc gacgatgatg cgagggtcgc
      481 cttcggagaa tcggcgcgcg agcgcggcga ggtcgaactc gtggccgtcc aagagtgcgc
      541 gagtattcat gaggtcacct ggcttggatg cataagttga gcagtgatgg tgactccggc
      601 tgaagtcggt tgacgctcta gctcatcgac tcttgacatc ttggtggaaa tcgcaatctg
      661 acgcgccgta tccacatcac gctgactcat cccgagtccg cactggggtc gtggcgcgtc
      721 atcgtcgtga gtggtagaac tgcccgatcg ccgcaggggc tacccagtcg acttggtcag
      781 gtgctcccgc agttcccggg tggctcgacg ctgcgcatga gggtctccat cgttgctgtc
      841 gatctcgtcg agcaagcgga tcaggtcttg cctggtgctc tcgaactcga tacgcagccc
      901 gatggtcatg ctgtcgtcct ggtccgcacc gacgactatc aagggcgtcg ccgagtctgc
      961 gcctgcttgg cgggcgtggt caacgaaacg ttccaggtca cccaggggca acgtgtcccc
     1021 cgggtagggc aggtcgagtt ctatgcgtga ggtcacgacg tcagcctatc tccggctcca
     1081 tgctgcagct ccgaatcagt tccgttgtta tcttggcgtg ccctgtcggc gacgggcgcg
     1141 ccaggtagtt ctcaacgaga tccaaggtga tgcttggcga gccttctgat cttggtaagg
     1201 cgcttggaga ttgcgctgcg gttgggctag ttggaccgcg ttggagtgca gtcatcgttg
     1261 gtcctgctca gttcattgca ggaggtgtcg gtgtcctgaa cgtcctcggt cttgatctta
     1321 ttccagtcga tctgtacgcc agtgataccg atcttgatac ggaacgacgt cccctggtcg
     1381 gccagcatgc cgaccagcga ccggaggagc aggaaggttc ccaggagcgg gatgatccag
     1441 tgcgtggcga tatgggtgcc gaggatgctc atgacgcctc gaagaagctg gcggcgcgct
     1501 tgcggattcg gtccaggcgc ttggacaccg cgctgtggtt ggcgtagccc atctgatcgg
     1561 cgatgtcggt gaggctggtc atgccgctgc gtaggaggat gatgagttcg cggtccttgg
     1621 gcttgagtag cgtcatgaag tcaccgacga ggacgcgatc gatgacctcc gtctccgggc
     1681 cgtggacagg caccccatcg ggcagttcga cgaacgtgac cttgatcttc aggcgtttgt
     1741 ggtggatctt gcgctcgaag tcttctttgg cgtagctcca tcggtccgag aagtcgtcgg
     1801 ccacgcggtt cgacttgatc gcgtcgatga tctcccgcaa cttgccgctg gcatccgcct
     1861 cgtcgacgac catgtccctg acgtctgcgg cgtcggcctc gcctagccat acatccccac
     1921 cttgacgtgg aacgccccag taggtgccag tcagaggcga gccgtcggcc aggcgcggcg
     1981 attccggcgc tacggcatca ccgacctggg gaaactcgga cagcaacgcc tgcaccactg
     2041 atgtcaccgc gggcagccag aaatcgaggt tgtgggcgag cagacgcata gggtcgtccc
     2101 gagtgaacgc ggccatcgat gaccccgaaa ccagatcgcg ccacacgacc gaggcccacg
     2161 ccctggatag tgcctccgag aagttgacgg ggaggtacgg gtccaccgga gtgtgctcag
     2221 ccacgaacgg ccactgccca ccgtgcagga ggggcaggcc atgccgctcg accaccgtcc
     2281 gcggtagcaa gtggaacagc ggcgcgtact cgtggtacct cgacctggtt cgagggatga
     2341 acacgacgtt gatgtcaccc tgctccgcga tcgccagcat ccgcggactt agatccgctt
     2401 cggcgatcac ccgcctgcgg aactgcgccg cctcccactg catgttccac ttcgcgatct
     2461 ggccggtcat ggccaaggtc agctcgctgc taccaccgct gatcggcaac gtcacgaact
     2521 ccggcgcctc aggttcccgt gcgcgcagca tccggcggta cagcggtgcc ggtgacatcg
     2581 tccacaatct cgggtacaga tctgaggtcg cgcggtggtc actggtgtca agtacgacgt
     2641 cggcacgacc accgcgtacc cccgtcaccg tggcaccgac cgcggcctca gcatttgcct
     2701 gctctgctct cataccctgc tcacgacact cgaaccgcga tccgttccag tcctccagag
     2761 ctttcctccc caggatccca gccgctcacc ttgagcggcg gtccccacag agttgacgca
     2821 acgcgcgatg gttccgcact cccgtaccta gaggtcaggc cgaggaccgc tcgctcatcc
     2881 agcccgaccc caaggtccac ccgttcccac cgcccgcatc gagcctccgg tcaccaggcc
     2941 gcggacaaac cgcgtgacct cggctggccc gcttcgtccg gaagcccgtg gcagctccaa
     3001 ggcttgcccg catagtagat cggggaaggg tcgtggaggc ggcgcaccgc cgtaggagtt
     3061 gtactggcct tcggccgggt cggttgccgg ggcgggccgc acgccatcac ggcttgcgcg
     3121 agtcgctggc cgggctgagt cgctggtgcg tgttacgcac aattccggca acttccgatc
     3181 gccacgaatc actatttgat cttgatcgtg gaacgaaact ctatctgagg tgcgacaact
     3241 ggagccgatg acccaatcta acttttagga gtcagccaga tagtccagca ggcgcactgt
     3301 gacggtctgc gactccgcta acgggtaact ggtcccgaca ttttggtgac atgctcggaa
     3361 ccgatcgcac caacgtgatc atgctggtgc tgaacgatca atcaatgacg tgaagtcggc
     3421 tggccaacgg tgagcaagta ggtgaagagc ggagacgatc gaggagatcg gagcaccgtt
     3481 ggtggccgag acggtcatgt cagcaaagtc agtgcgcatg accgagtctg cggtgtcgtc
     3541 gccgatgcgt cggacatgga cttcggtgac atggaagcta tcttcgatgg agtcgcggat
     3601 gagtctgacg tctcctcgga cgtcaccgct ctgctcggcg ctgaccagga tgcgacgcga
     3661 cacgccacgt agatcgacag catccaatgc gaacccactc agcagttcag caatgtcgtc
     3721 ccatcgggcg gccaagcttc cgtctctacc tcgcagcctg cgcgcgtcgg tcgtgaccag
     3781 cacgcgccat cggccgacgt tggcgatcaa catccggttg cggacacgcc acgttgaagt
     3841 ctcggagtca gtctcgtctt gggctgccgg gtgttcttct tgatcaccat cgagtgcttc
     3901 cgactcgttg tcgatcacta gttgcgctcg acgcgctcgc catatctgtg cgttcgcgac
     3961 taccagcgga ctgacatcca catcttcgag gatgtcggtc atgtcttcta ggcgctcaag
     4021 cgacatcatc gaaccgatac gaatccacag atcaggtttg gtgaccgcat tcaggttgtt
     4081 gagcaggtac ggaagcaata ctcgcaattc gacatctgac aactctccgc cgaatgcggt
     4141 ctcagaatgg cggacatctt cgggcgagat gccgaggtgg agcaattcgg ctgcacgttg
     4201 caaacgaagc gcagcgtctt cggtgaagac ttcctcagtc gactcctgaa acgagtgcag
     4261 aaagtctgca ttgaagttgc tgtcctcggt ttcgggtgtt gcgctgcgga tgagacgtcc
     4321 ggcatcgtcg gcggtcagca gccctctgcc acccttgacc aggttggttt gaataaggcg
     4381 caccagcggc tcgccaggtc cgccgaggtt ggtggatcct tcactgcttg cgggcgcagc
     4441 cacctcagcc agggatgcta gatccgtcac cagcacacgg cgagcctcct gcgcttggcg
     4501 gcggagcgcg gacggaggct cgatccgaga atccaacgac accatcatcg gctctcgcgc
     4561 ggcgagtgct tgaacctcag cggcggtcga tggcctaagt gtgtttcgga tgaagatcgg
     4621 cctgctgtcc gacttgcctg cctcgcgcca ttcgacaacc aggtcgggca tatacgaatg
     4681 attgaagtat tcggttgcga cgatctttgc gtcaggggtc agcgaggcga cctcttcggt
     4741 gacggcttgc ttcactcctg tcacgatttc gtgcgggttg gtcgacgcca ttgccaaccg
     4801 gaccctctcg gccacagcat cgccgcgggc attcatttct tgcccttgcg gttgagtcga
     4861 ctctcaacga tcgacaactc ctccgcgctg agcatgagcc cctcctggcg ctggtggacg
     4921 acaagcagcc agaggcggtc ggccactgtc gacagtaggt cgatgtcaat cgcttgaccg
     4981 tcgagaactt cgggatgctt gcccagggcc gcatttatgc gcccagccga agtcaacgct
     5041 gtccagtctg tctgattgaa gggatgccgc gtaatccaca tgaactcgcg tcgcccgtct
     5101 tcaccgtttt taatatcgcg agcagtaata ctgtaggcgt tggcgagaaa ctcccaatac
     5161 tcctcgccct gcttacctcc ggtcgatgta tagttcttca cttcaacata gaccggactc
     5221 ggcggcgagg tatggatact tccgaacagg tcgtaccttt tcattttgtt atcgagccgc
     5281 gtcaacgtgc aaattggagc attattgtac gcgtcgaagg ggagatcaat ccaggtcgtg
     5341 ctttccaacc aacgcttggc gaagtcgacg ccatctatcc cgtcctgttg cacagactcg
     5401 gcggccgaca tgactcaagc ttaacgcgtg cgacgcgcat gagcgtactt ggacaccttc
     5461 ggagtgtcgc tcgatgggtc tgccgtcgtg gacagcagcc acttgaacgc cgacgcgttg
     5521 acaggagtcg ttcgatcacc ctcttggttg aactcgacgc cccaggtcag aggcacgcat
     5581 cggctgacgg cgacctcgat cggacttgcg cgcttcgcgc gacccaagat caagatctcg
     5641 atctttcgcc cgatcgtgtg acgaccacag tccaggattg tcagaccctc tcgttacttt
     5701 gcgcgcatga acaaccccgt aacgtcatgg gcgtctgggc ctatgattgc gttggacctg
     5761 gagaccaccg acgtcgaccc tcaccgggat cgcatcgtga ccgcatcgat agtcatcatc
     5821 accccaggtt tgcccggcga aacaaccgag gtgaccacgc tcaactggct ggccaatcct
     5881 ggcgtggaca tcccggtcga ggccaccagg ctgcacggcg tcaccaccga acaggcccag
     5941 catgatggac gaccagcagc cgacgttgtc gctgaggtcg ccgcggatct ggctcaactg
     6001 tggacgccca ccacgccgct gtgcgcgttt aacgcctcct atgacttgac catgctcgac
     6061 gccgagttgc gtcgttacca cggtcgcggt ctcccgctcg gaggatcggt gatcgaccca
     6121 ttgtgcatcg atcgacatct gcgcccggtt agtggctggg acgacaggcg cacactggcc
     6181 aacgtatgcg cgcattacga ggctcgactg gatgcggccc actccagcgc ggaggacgcg
     6241 atcgcaacgg cccgcctggc ctggctgctg gcaaagcgcc atccgcaagc agttggcctg
     6301 cttgacctcc atgagttgca caagcggcaa gctggttggt tccaaaccca ggagaacact
     6361 tacgccaacc gccaggaacg caaactcaag caactcgtgg cccgcggtgc cagtagtgag
     6421 aagaccgatc agatgcgcga gcggatcgcc aagatccgag cgtcagccaa atactggcca
     6481 ctccgacctg acctcggcga cactgcccag cccgtacgca cacgaccagc ggcaccccag
     6541 ccaggagaac cggccaacgc ccgcgcctct tggactccgg agttggatgc ctcgctacgc
     6601 gaggaatggc tggcagcaga ccccggcgcc ctggctgaga cgctacgcaa ggagctggcc
     6661 acccagttca ggcggacccc aggcgcgatc cggtctcgtc tgttgaagat ccggtgtgat
     6721 cccgagttgc cgagtagcac ttgtgacgaa cagcgcgccg cggagctcca gcgagtctat
     6781 gacgccgagt acgggcgata gtggctgcat cgggtgctgc ctggacatgg tgaccttgcc
     6841 aggcagcacc cggctcgtct ccatcgccaa agcgcagatc gtcagtcccc acccaggatg
     6901 aactctgcac aagccgccaa ttgtggaaca agccccagtc caagtcagcc gacacctgac
     6961 agcaagttgc ctccacgagg cgccaagagg ctcggcctcg ccttcgctct agacttgatc
     7021 gggtggacct ctccgacgcg atctcgatca ggacacttga cgggggcctg tccaccgagc
     7081 tgcaggcacg aggtcatgat ctttctgacc acctgtggtc agctcgactg ttgatcgacg
     7141 atccagccgt gatcgttgcc gctcacgtgg cgttctaccg ggctggagcg tcggtggcga
     7201 cgacggccac ctatcaggca tccttcgacg ggttcgctcg ccgtggtgtt gactacggtc
     7261 aggccgagct gatgtttcgg cggggagtcg agctggcgca gcaggctcgt gctgagctgg
     7321 cggaggacgg gcatcagcgt tgggtagcgg cgtcgatcgg cccatacggt gcggcgttgg
     7381 cagatgggtc ggagtaccgc ggtcgatacg ggctcagcgt gggcgagttg acggactggc
     7441 atcggccacg gttgagcgtg ttggcggacg cgggggcgga tgtgctggcg tgtgaaaccg
     7501 tgcccgatgt tgatgaggct gaggcgctgg tggcggtgct tggggaaatc ggcacagccg
     7561 cgtggttgag ctacacggtg gagggcggtc ggactcgggc cggtcagccg ctggatgagg
     7621 cattcggcct tgtggcggcc agccgcgagg tcatcgccgt tggggtgaac tgctgctcgc
     7681 cggtagaagt cggccctgcg atcgaggttg ccagagcggt gacggacaag ccggtcatcg
     7741 tgtacccaaa cagcggtgag cagtgggatg gtaagtggtc gggttcgtcc gcgttcaccg
     7801 ctgggatggc ccgggagtgg gtagcagccg gagcgactgc ggtgggtggc tgttgccggg
     7861 tgactcctca gcagatcgcg gagctggccg cggtgctcga cgagaccaag tcctagatcg
     7921 tgagtgcgag agccttgcgg agagcgcggg ccaagtcggt gatggttcct ggtgctgcgg
     7981 ttcggtcgag gaggtcgaga ccgtgttcga cggtgcggtc gccgcggcgg gagcctacga
     8041 gcccgatgtg gcccagcagg accttcatcg atcgttcggc gtcgggccag gacttgttga
     8101 tgacgtgggc gacgaaggct gaggcgcggt agctgtagaa ggtgcggacg cggtgctcgg
     8161 agatgccgtt ggccgccagg tcgaagaagt cgagtgccct gccgcgctcg cccaggtcca
     8221 gttggatctt cccctcgtgc caggcgaact cggcgtcgtc gacccaccaa gcccagtgtg
     8281 ggtcgcggtc ggagacgccg tcggcgtgca ggtcccgggc tagacggaag gtcttacggg
     8341 agtctccgtc ggcgccgagc tcggccagag cacgcgcctc gcgcagccgg aacagcgact
     8401 gaagccgtgg ggtcagcttt gcgtcgagag cggacctggc gatgtcgagg gcttcttgag
     8461 cgtggccgag gtggctggcg tgcatggaca tgttctgcat gatgaacagc tccatgctcc
     8521 ggtcgcccgc tcgccgggcc aacttgagag cttcgacgtt catctcatga gcttgctggt
     8581 gcctctccgc atcgtagagg ctccaacccg cgacctcggc cagctcggcg gtggccgcat
     8641 cagcgtcgcg cgcaaggccc ttctggatct ctgaggtctt gacccggtga cgtgcctgct
     8701 tgaacgcctg aacgatcaac ggggaagtga ccgcaccgcc atactgctga tcgaggcgga
     8761 cgaagccctt gatctcgcca tgcagccgtt caatgtagtc cgaatccacc cttaccttag
     8821 tcgaaagtgg gtgaggaagc gcggtaatat tggggtgcaa tagtgctggc gccccgccga
     8881 acggagaacc attggcgatt tgcgcctttc ggtcttcctg cgcctgctca agttcaatga
     8941 tcctcgcgcg ttcctggtaa gtgtaggccc ggtcatactc agtcagcagc gcgccaccgg
     9001 cctcatacgc ctggtcggcc gcctcccaga agctcctcgg agcggactgc cgtcctgcct
     9061 cgatgtgcga gatgctggtg cgcgagtagt gcgtcagtcg cccgaggtcc gactgcgtca
     9121 gcggcgaagc ctttcgccaa cgggccaagc tggcccccag cgagtgccag cgcgccccga
     9181 cgtcctcgcg tcgaccagtc atccagattc ccagagttcg tccgacaaca cctcctccca
     9241 gcctagccag tgccatagat caacttgtct gtccaggtgt gggtctaact cccacaccct
     9301 tcccgcgtcg cagtggtccg tagttagttg tgtacgtagc gctaacggcg ctgtccgccg
     9361 atgccgccag gtagggggcg acgcgccacg cagatcacgt ggtcatcggt gaccgagacg
     9421 agcgtcaagg agggcaggtt ggcaactcat gatcatgctt cgacacccgg ccgtcttgac
     9481 gatcgcgggc acggccattg cgttcttgat cttgttggtg gctctgcgca gagtcggccg
     9541 cgccgagaac ggccataccg gtgatcaggc ttcacccgct gtgggctcac cgccgccagt
     9601 gggacgaagc gagaacgagt accccacggt tcgtctgcca ccactccaag acgtggacgc
     9661 ggtgcgcctt gtgcgggggc atgttcggtt ccgccccgcg cccgcagacg ccgacgagcc
     9721 ctagccactc caccccaccg acaccggccg gaacgtagaa caggcacctc ccggtcgggc
     9781 caagaagaag atcaacgaag ggatcaccat gattgccacc ctggacgagt tcgccctgga
     9841 tgtgcagatc gtctccgact ctcccgcggg ggaaccggcc gcgtgcgcga ccgacgacgg
     9901 gtgcgcatcc acgtgcgcct cctcgtgcgt cagcaacgtc tgacctgatc acggcgccgg
     9961 gactacccgt cccggcgcca cctcgtcagg aggcttcgag atgtccaccg acagcaaact
    10021 cctttaccgc cacaccggcg ccgcactctt gcgagctgct gcccgcccgc tcgacgaaac
    10081 gcaggatgac tggcccgacc tgggcgatac cgagagctgt cgaacatggt tgaagcggac
    10141 gtggtcgcgc tccaccttcg cggacgccgt gcggatcgcc agtcccacgt tcgcggaacg
    10201 gctcgactcg ttggactcgc tgcgcccgaa ggaagtgcga cgagcagcgg caaccgcggt
    10261 tcgatacgcg ctgcgcgcgt gcacccggca taccccgttc ggactgttcg ccggtgttgc
    10321 gtccgcggag atcggctcgc ccgggatgag ccggtggggg caggggcatc atgaggtcgc
    10381 gcgtgtcgac tcccagtggc ttgcgggggt catcgcacgt ctcgaagccg aaccgattct
    10441 cctggaacgg ttgaaggtca tgttcacgaa ccttgccgtc gagcgaggtt cgcggttaga
    10501 ggccccgtgc ggaccggaga cggtcagcat tcggctgacc gggccggtag cgttcacgca
    10561 ggcgtctgcc tcgacgccca tcctcttcgc cgaattggtc gacctcctgc tggcgaagta
    10621 cccgaacgcg gaccgggcga cgatcaccag gatggtgagc gaactcgtcc gccagcaggt
    10681 cctgatcacg agcctgcgcg ctcccctgac cgtggttgac ccgcttggtc acctgctcga
    10741 ccaacttcat gccgcaggcg ccgagtacgt ggccggtctt gaagcgcttg tcgatgaact
    10801 gtgcgccgtc gatgttctga ttcgtcggca caaccgccat gcgttgggcg acaaccagaa
    10861 ccgcgccgtc cggatcgaga tcgggcgtcg aatgcgggag gtctccaccg gcgggcggac
    10921 tcccttggcg atcgacctcc gcctggactg tgacgtgcgt gttcccgagc aggttgttcg
    10981 cgacgtcgag ggcgcggcca ccgcgttggc tcggctcacc gcacagccga ctggcgagcc
    11041 tgcttggcgc gactactaca ccgtgttctg cgaccgatac ggcaccggca ctctcgtccc
    11101 gctgaccgag gtagtccatc cggacagcgg gttggggttt ccttctggct acccgggaag
    11161 tgttcgccct tcttccttcc gaaccggctc ggaccgggac cagacactgt taagtctggc
    11221 gtggaccgcc ctggccgacc aaagacgaga ggttgtcctc gatgaacccg ctatcgagtc
    11281 gttgatggtc agcgaggcca cgcagcctcg gtatccggct cacgtcgaag tggcagcccg
    11341 catccacgcc accgacatca atgcgctgga tcagggtgac tacctgctca cgatcacccc
    11401 aggccggagc ctcgggacgt tcacctccag gttcgccacc atcgccccgg ggaccgatct
    11461 gcgcaggatc tacgcgtctg tcccgacagt cgccaggcag gccgtccccg ctcagttgtc
    11521 tttcccgccg gtgtacgcac acgccgagaa cgtctgccgg gtacccgaat acctcccgga
    11581 cgtcctgtcc ctcggagaac acagggcaga cgccaccatg gcactcgacg atctcgcagt
    11641 caccgccacc cgggatggct tccatctggt gagtctgacc agtcagcgga tcatcgagcc
    11701 gcaagcgttc cacgggctcg ccctgcagaa gcagtcacca cccctggcca ggtttcttgc
    11761 ccacctctcc cgcggtctgc aagcttcatg gcacaagttc gattggggca gccacgccaa
    11821 ccagatgccc tatctgccaa ggatccgcca cggccgtgcg atcctctcgc ccgcacgctg
    11881 gcgtcttgcc agtgccgacg cgcccagtct ggaatcctgg cgtaagcgct gggacgttcc
    11941 tgacctggtc gagttggccg ccgacgatcg cagcctgcga ctgaacctca acgagtccac
    12001 ccacgtcgcg ctgctcgtcg cccacatgga gcgaaccggc gacgcgaccc tcgtcgagac
    12061 gatcaacgat cctggagaac tcggctggat cggcggcttc gcccatgaga tcgtcttccc
    12121 gctgacatcc acccaggctc ccgcgtcggc acctacagga agaactgcgc gacggatctc
    12181 ctgccgaacc catggcgtgg tgcctggtgc gccaacagcg gcgtggttga acgcaaagct
    12241 gcacacgcac ccgcagcgga tcaacgagat catcaccgac cggctgccca cgctgctcga
    12301 tccccttggc ggaccgccgt tctggtttgt ccgctaccgc agcgcaactg agaccgatca
    12361 cctccgactc cgactaccag ccgacggcac ggacgtgcat gtagcactcg gtcgatgggc
    12421 agaggctttg cgtcgtgacg gggccatttc gcggttggtg ctcgacacct acttccccga
    12481 ggttggccgc tatggagcgg gtgaagcgat ggccgccgcc gagaacgttt tcgtagccga
    12541 ctcccaggcc accgccgcgc aactccgcta cctcccggag cagcgcgagg cgatggtcgt
    12601 cgtgaacatg gtcgccacgg tgtgcgccct cctcggaggc gaggtcgcga tccagtggct
    12661 tgtcgatcac cccgctccgc cgggcccggc tatcgaccga cctttgttcg atcaggtatt
    12721 ggccttgctc cgcggtcccg cgacgagccc gccggatggg tggaaccaga ccctcatcca
    12781 gacctgggag cgacgcgccg aggctctggc cgcctaccgc tcccacctca ccgacgataa
    12841 ccaggttgcc acggcagtcg agtcgttgct gcacatgcat cacaaccggc tgatcggcat
    12901 cgaccgcgac tacgagatcc gctgtcgacg cctggttcgg caggtcgcgc tcacctgggc
    12961 acaccgacgc ggaggcagcc gatgacgccg accgactccc tcgccgacgg ggcggcgggc
    13021 atagccctgc tccacttcga gcgtgcccgc actggtgcct gcgcgaccat cgacgcccac
    13081 ccgtgggcgg tcacgatgac aaaagggcca gtcaccgccc accccgatgt cgcgagcttg
    13141 taccgaggtg cccccgcagt ggcgttcgcc ctcctcaccg caggtcatcc cgcctatgcc
    13201 gctgctgtag ccgacctcga cgaacacatc gtcacgctga ctcgcgaacg cctcgaacgt
    13261 gcccaccgcc gcatcgacaa ctccctgctc cccgacatcc gcgagttcga cctgatcagc
    13321 ggcctgaccg ggatcggtac ctacctgctg caccgcggtc accacctgct caccgaggtg
    13381 ctggcctacc tcgtacgcct caccgaaccg cttggtgagc tgccgggatg gtggtgcggt
    13441 ccaccgactg acggcctggc agaagagtgg atcggcggac acggcaatct gggcctcgcc
    13501 cacggcatag ccggaccact ggcgctgctg gccatggcga tgcgccgtgg cctggtcgtc
    13561 gatgggcagg tggaggcgat ctccacaatc tggcgatggt tcgacgactg gcgtgtcgga
    13621 actggccgcg aggcgtggtg gcccggcagg atcaccggag ccgaactcgt gaccgggacc
    13681 gtcacacaag ccggtccaca gcggccctcg tggtgctacg gcactcctgg tcaggcccgt
    13741 gctctgcaac tcgctgccct ggccctcggc gacacacgaa ggcaacagca ggtggagaac
    13801 acgttggcag gctgcgtcac cgaccccagc caactggggc tgctcgtcga caccaccctg
    13861 tgccatggct gggcaggcgt cgtcctcacc acctggcgag cagcagcgga cgccggtccc
    13921 gacagcgagc tggccgccca cctgccccgc ctccgagaac tcctcgacca ccatctccag
    13981 acgtcaacga cgccaggcca cggcctactc gaaggtgaag ctggccagca gttgacctgc
    14041 ctggccatcg acaccgacca gcctgtccgg accacgtggg acctgtgcct gctggtgtcc
    14101 ggctgagcca cactcaaccc atcactacgg aaggacctga tgaacaccac caccgacagc
    14161 gtcccggaga cgctgcgggc ctgtatggtc gacaccatcc tcgccgcagg ccacgcccaa
    14221 acgcccgcgg tggaggccgt cctacgcgcg ctgccgcggc accggttcgt gcccgaggcg
    14281 agcctggagg acgcctacgc cgacatcgcc gtgatcacca agcgcgccgc cgacggcgcg
    14341 gcgttgagct gcgcgtcggt gcccacggtt gtggcgatga tgctcgacca gctcgatgtg
    14401 caccctgggc aacgggtgct ggagatcggc gcgggcaccg gctacaacgc cgccctgctc
    14461 gccgaactcg tcggacccga cggcgccgtc accacggtcg acatcgacga ggaagtcacc
    14521 gctggggccc gccgcggcct cgacgcgacc ggccacgacc acgtccgggt gatcacccgc
    14581 gacggcgcgc tcggtgcccc cgaacacggc ccctacgacc gcatcatcgt caccgtcggc
    14641 gcctgggatc tcccgcccgc ctggcacgac cagctcgtcc ccggcggccg gttggtcgtg
    14701 ccgctgcgct ggcgcggcca gacccaagcg gtcgccttca tccgcgagca ggaccggctg
    14761 cgctcggacc gcatgaacct gtgcgggttc gtccccatga tcggccagga cggcgagaag
    14821 aacggcacca tcaccaccga cggaaccgtc accctctact acgacatcga ccagcccatc
    14881 gaccccacag cgctgaccgg cgtcctcgac cagccccgag tcagtgtctg gtccggggtc
    14941 accatcggcg cgtccgagcc cttcgatggc gtgtggctca ccctcaccgc cacagacccc
    15001 gccacctgcc gcatcgccgc caagcagacc gccatcgaca gcggtctgtg cacccccgcc
    15061 atcggctccc gcagccccgc gctcgccgag gacgtcagcc tggcctactt cacctaccgg
    15121 cgcctcgacg ctcccgaggc ccgcttcgag ttgggcgccc acgcccacgg accaatcggc
    15181 gaacagctcg ccgagcgact gtgcgcccag atccgcacct gggacaacga ccgcaaccac
    15241 cacccccaga tccatgcccg ccccgccaac acccagaccg tcaccctgcc cgccggacag
    15301 gtcatcacca agcgagacag caccctggtg ctcttgccgt agcgccacgc ggcctggtca
    15361 tcggtcgccc gatgaccagg ccgccttgct gtgcacgctt tttgtaggtg gaagttagac
    15421 gatcagaatc gaaaacagcg ctcccgcagc cagggctggc cccaaaggca cgtcgcgacg
    15481 ctcgctggat ctgcgcccga tcaagcaact cgccccgtga agcgcgccga tgaacagccc
    15541 gatcacaatg gcccgaattg ctgccgacca acttgtccaa ccgagagcga gtaccagcag
    15601 agccgcgagc cggatgtctc ctccgccgat gaatcccggc gagatcagat aggcgatggt
    15661 gagcagcacc agacatacgg cggagcagat gacgccgcgt atgagcggtt ccggctggcg
    15721 actcaacaca gtggcagcag cgaacaagat cgtaatagcg gcggcagcag cgatgatggg
    15781 tttggtgggc agtcggtgtt cgcgtatgtc gatggctgcg agcgggatga tcagcgaggc
    15841 gaggaccgag tacgccacaa gcgtcgcgcc catgcccagc cttgcggcga ggagcgcgta
    15901 ggtcaccgaa ccgcaagcca tcaccaagcg gtagtcgacg gacgacgaag tgggaagagc
    15961 gagcgaccgc accagggcgt tggcaggggt ggccgacagg gttccgacca gtgcccaaac
    16021 tccgataaag atccaactgt ccaccatgtc cctctggttc tcggcgtgac ccgaatgatg
    16081 gaagtgggat tctccatggt ggcagcttca agtcaataga gcgccggatt gtcacgctag
    16141 gtgtagttga cctagaaatg acgacgcccg ttaggctgtt cgggttgtat ccgtgttttg
    16201 gcggcattgc gtcatgtgcg actcctcatg gagacgttga tgtcccctgg gtgaggggct
    16261 gtagaagtca taggacgatg ctggtgagcc cgttggggcg aactgactct cactctgggg
    16321 gttcttgtgt ctccgaagac gatcgcggcc gtcaccatgg cggtggtggt gctggcggcg
    16381 gggtgcggtg gctcgtccgc cgatccgccg ccgacctcgg ccgggctgcc gacgagctcg
    16441 ccaccgagta ccgcggtggc gacgactacc gagtcggcgg acgagcggga tggccgcgcg
    16501 gcctccgacg cctacctcgg catgtggcgt gcgatggcgc aagccgggct gacctcggac
    16561 tggcagtcgg tggagctggc gaagtacgcc aagggcgagg cgttgagcac gatcacccgc
    16621 agcctctacc gcgaccacac gaaccaggtc gtgaccaagg gcgagccgaa gaacaatccg
    16681 caggtcacca gcgtggagag caacacggtg acgatcgcgg actgcgggga cagcaccaac
    16741 tggctgaagt acaagaccac gggcgagctg aaggacgaca cccctggtgg tcgtcgggcg
    16801 atcaccgcgg aggcgacgcg ccaggacgat gggtcgtggc gggtcacctc gttcgtcgtc
    16861 caggcggtgg ggacatgctg aggctgacga tctccgccgc cggattagcc atggccgcgg
    16921 tggtggcctt cgcgcccgcg gcgacagcgg acgatggatg gggtggtgcc gactgcgggc
    16981 aggtgcccgt cgccgggtgc gatgtcagcg ccgggggcgg cggcggacac aacggcggag
    17041 cggtgcatct acccggaacc ggcggggacg acgattccgc ggttggcccg gactactcgg
    17101 ggtgccggtg ggacaaggtc gacgactact cggagccggg gcagccgacc acgggcggtg
    17161 gttggtacct gctgacgtgc ttaccggact tccaggacgg tccgttctgg gtggcggatg
    17221 ccgctcccgc gccggtgtcg ccgcgagtgt tggcggagac ggcgcggaat cggttgtcgt
    17281 tgccgcggcc gtcgatcttg gcgagtccgg cgcagaacca gcttgtgaat ctgccgacct
    17341 ggttgtgggt ggaccgcggg gcgtgggtgc cggtgtcggt gaccgcgtcg gtgccggggg
    17401 tgtcggtgac cgcgaccgcg cggccgacgg cggtgacctg gtcgatgggt gacgggacga
    17461 cggtcacgtg caacgggcct ggtgacccgt tgctcggtgg tgatccgcgg gcggcgtcgc
    17521 cgacgtgcgg gcataccttt cggcgggcga gtgagcggta tccggtgacc gcgacgatcc
    17581 attggtcggt gtcgtgggcg ggtgccggga cgggtgggac gttccccgag ttgaccacgt
    17641 cgaccacgac ggcgttccgt gtggtggaga tccaggcgct cggcgctcgc tgactatctc
    17701 gtatagacgt tctcaatctc attcttcttg ctgggtgcgc tgtttctctg aatgcgtgcc
    17761 ggggcggagc tgtgcctgaa ggagggcatc gggtggcaac tgtgacatcg cggtcggctg
    17821 cggacgagag atccggtccg cgtggctggt cgagcaccaa gcgggcgggc cgcgcggcga
    17881 cgggttctcg ggtcaacggg gctgtgcagc ggcggcgtgc gccgtatctg ctgctcggcg
    17941 ttctgctggt ggtggtgtgc gcgggtgcgg gggtgtacgt ggctacgcag gcgggcaacc
    18001 gggtcacggt gttggcgttg gcgcgggcgg tgacggtcgg ccaggtactt gcggggcagg
    18061 atctgcggca ggtcagcatt tccgtcgaca gtggactgga cgtggtgacc gcggcggagt
    18121 cgaccgcggt ggtcggaacg acgatggcct acccggcacc ggcggggaca ctgctcagca
    18181 gagggcttct cggcgccgcc ctggttcctg acgccgggtc ggcgatcacc gcggtggggc
    18241 tgaaggacgg tcagttcccg ccgtcgctga cacccggcac gcacgtcctg gtgctcatca
    18301 gcccaccagc ctccaccgcg acttcgacgg cgtcggtagc gccgccgcgc acggtccgtg
    18361 cggtggtgac cgatgtccag gcgcggcaga gcgagcagac cacggtggtg tcgctggagc
    18421 tgccggaggc cagtgcccgt gagttggcgg gagcgtccgc ggcgcaggtg tcggtggtcg
    18481 cggtcggggg tggccggtga tgttggtcgt ggtctgctcg gtcaagggtt ccccgggggc
    18541 gacgaccctg tcggtggcgt tgggcgcgcg gtggaccggc cccgaggagc cggtcgtggt
    18601 cgaggccgat ccggggggcg gggatctgtt ggcgcggtgg cggctggagg agaacccggg
    18661 gctcaagtcg ctggccgcgg cggcgcggcg cgacagcgac cccggtctgc tggcccagca
    18721 cacccaggtg ttgcccggtg ggttgcgggt ggtggcgggg ccggtcggcg cggagcaggc
    18781 ccgctcggcg ctggcggtgt tggcgggtgg gtcgtcctcg gtggtgcgtg ccgcggcgga
    18841 ggtggcgggg caggtggtga tctgcgatgt cgggcggatc gacgcccaat ccccggcgct
    18901 gccgctgctg cgcaccgccg aggtgaccgt gctactggcg cgggcgcgcg acgacgagct
    18961 ggcgcacgtc gcgcagaagc tcgacaccgt ggcgaagtgg acaccacacc cagccctggt
    19021 gctggtcggc gagggctacc caacccgcga ggtggagcgc gagctggggg tcgacgtgct
    19081 cgcccggcta ccccatgacc ctcgtggtgc cgcggtgctg ggcgggcagc cggggcgccg
    19141 ctcgccgtcg cggtccgctc tgggcaaggc cgccgcgtcc ttggcagacc tcctgcgcgc
    19201 ccaagccccc accccgcagg acaacctgcc cgccgacctg cccgctgccg atgtccacct
    19261 gaacggaacc cgcccatgac cgagaccacc accttcacgc gcgtagccgc tgcgcagacc
    19321 ggcgtcgagt cgggcagcga ggtcgaggcc atcggtcgga tgcgggagtc gctgcgcctg
    19381 gccgtggccg cgcagctcgg tgaccgggtc agcgcggacg acgcagccgg gcgaacgccc
    19441 atgaccccgc ccgagcgccg cgcgctcgcc gctgtgctgg tgcaggaggc cgcggacgcc
    19501 tacgccaacg gcgagctgga gcgcggcggc accctgctgt cccccgaggt cgaggcccgg
    19561 gtcaccgccg cggtgctgga cgacctggtg gggatgggtg gtcttcagcc gctattggag
    19621 gacgagtcca tcgagaacat caacgtcaac ggggaccgag tgttcgtccg ctacgccgac
    19681 ggccgccgca cccgcctggc gcccgtcgtg ccgaccgaca acgacctgat cgacctgatc
    19741 cgcgacctcg ccgcccgctc cgggatggag gaacgccggt tcgaccgcgg ctcgccgatc
    19801 gtgaacttcc gactccccga cggtgcccgg gtctccgcgg tcatgtcggt gaccgagcgg
    19861 ccgtcggtgt cgatccggcg gcaccgctac agcacggtca ccctggccga gctacgcgaa
    19921 atgggcaccc tggacgtggc gctggagtcg ttcttcgccg ccgcggtccg ggcgcgacgc
    19981 aacatcctcg tggccggcgg tacggcgatc gggaagacga cgatgctgcg cggcttggcg
    20041 tcggcgatcc cgcccgagga gcggttgatc acgatcgagg acgtagccga acttgggttc
    20101 ggcgacgacg aacaagccca ccccgatgtg gtcgcgttgc aggcgcggga ggcgaacatc
    20161 gagggccagg gcgcggtgag cctggccgat ctggtgtggc aggcgctgcg gatgtcgccg
    20221 gaccgggtga tcgtcggcga ggtccgcgga cgcgaggtca tcccgctgac caatgccatg
    20281 agccagggca acgacggctc gatgggcacc atccacgcca gtagcagcaa gggcgtgttc
    20341 accaagctcg ccgcctacgc cgtgcagtcc ccggagcggc tggacatcca ccagaccaac
    20401 atcctcatcg cctccgccct gcacctggtg gtgttcctgg acaagccccg cggtgaaccc
    20461 caccgccggg tcgtgtcctc catccgcgaa gtcgtcaacg ccgagggctc ccaggtcgtc
    20521 tcgaacgaga tctggcggcc cggcagcgac cgccgcgcgg tccccggtgc cccgatccgc
    20581 accgagacca tggagctgtt gatggacgcg gggttcgagc cggatctgct cgacaacccg
    20641 gacgggtggt ggcagccatg accgccacca ccgcactact cgcgctcctc ggcgtcggtg
    20701 tcgccgcggg cctgttgttg atcgctgccg gtgcccgcgg ggttgaggcc acggacgtcc
    20761 cgtccaaggc ccagctctgg atcgccggac tgcgtcggca cgcccacgcg cggctgctcg
    20821 ccgccgcggt gttggccggg ttggtcgcgg ggatggtcac cgggtggctg gtgggtgggg
    20881 tgttgaccgc gttggccgtg gccgggttgc cgcaggtgct aggcggcacc cgcgggcacg
    20941 accgggcgct ggcgcggatc gaggggatcg cgtcgtggac ggagatgctg cgcgatgtca
    21001 tcgccgccgc ggccgggctg gagcaggcca tcctcgccac cgccgccacc gcccccgagg
    21061 cgatccgcgc cgagatcgag gacctggcga cgcggctgga ccgaggtgac cggctcggcc
    21121 cgtccctgcg gctgctggcc gatgacctgg ccgacccgac cgcggacctg gtgctcgccg
    21181 cgctcgtact tgccgccgac caccaggccc gccagctcgc cgaactcctc ggcgaactcg
    21241 ccgccgaggc tcgggagcag gccgcgatgc ggatgcgcgt ggaagccggg cgggcgcgca
    21301 ccaggaccag cgtgcgggtc atcctgatca ccaccctcgc cttcgcgggc ggcctggtgg
    21361 tgttcaaccg ctcctacctg gagccctacg acgccgcgtt cggccagctc atgctgctgc
    21421 tcgtcggcgc cctgttcgcc gtgtcgttcg tctggctcgg gcgcatcgcc cggctccgcc
    21481 ccgccgcgcg cgtgctcacc ggcctcaccc aactccccac tggcgcgacg gaggtccagc
    21541 catgatcacc ggcctgctcc tcggcgttgg gttcggcatc gggctgtggt ccctcgtcgt
    21601 ctggatcgcg ccgccgcggc agggtctgca cgcgatgctg gccgcgatca ccgccggacc
    21661 tgctccggcg ccgctgctga ccgcggactc cgggggttgg gggttgcgag tcgggaagcc
    21721 gttcgtccgc ccgttggcct cgctcggcct gccgacgccg cgggtgcggc gggatctcgc
    21781 ggtgatcggc aagtccccac agcaccacct cgccgagatg gccgtatacg gcatcaccgg
    21841 cctggtcctg cccaccctcg cccaagcgct actgctcgtc gccgacatgc cgatgccgtg
    21901 gcagatgccc gcactggtcg gactcatcct cggcatcgtc ggcctcctcg tccccgacct
    21961 caccgtccgg caagaggccg cccgtcgccg agacgcgttc cggcactccc tgggcgccta
    22021 cctcaacctg ctgcgcgtcc tgctcgccgg tggcgcgggt gtcgacggcg cgctcaccga
    22081 cgcggtcaag gtcggcaacg gatgggcgtt cgcgcagatc cggcgcgcgt tgaccaccgc
    22141 cgccgcgacc cgcaccacac cgtgggcccg actcgggcag ctcggcacgg aactcgacgt
    22201 caccgagctg tccgaactgg ccgcgtccct gtcgctggcc ggtaccgaag gtgcccgggt
    22261 ccgcgcgtcc ctggccgcca aggccagcgg gatgcgcact cgggaactca cccacgccga
    22321 aggcgaggcc cagtccgcga ccgaacgcat gagccttcca gtcctgatcc tgttcctcgg
    22381 cttcctgatc ttcctgggat tccccgccat gtcccgcgtc ctcatcggac tctgatcacc
    22441 cactaggaga accatgaacg tccacctggc agtccttgtc gcccgcatcc gcgccaactg
    22501 gcagcgcctg cgcaaagacg agaacgggta cagcaccgaa accgtcctcg tcaccgcact
    22561 gctcgtggtc ctggccctcg ccgcgctcgc catcctcgcc gcgaaagtga ccgagaaggc
    22621 gaacggcatc acgatgtgac cgcgcccatg accacaaccc caccccacac tctgcgggca
    22681 cgcctgcggc gactcgcccg ggatgaccgc ggcgcggtct cggtcgaact cgtgatggcg
    22741 acaccgctgc tgatcctgtt gctgctcacg gtgatccaat ttggcctgta cctacacgcc
    22801 tgccacgtcg cgcaaagcgc tgcctcacaa ggtctctcgg ccgcgcgcgt ggcgggcggc
    22861 acggccgagt ccggttcgac cgagacccga cgcgcgctcg accttctcgg cggcggtgtc
    22921 ctcggcggaa ccacggtcac gtccacgcgg accaccgcgg acgcctccgt cgcggtcacc
    22981 ggagtcgccg tgcaggtggt gcccttcctg accctgaccg tgcacgccga agcccacggc
    23041 ccggccgagg tcttccgagg agctggctga tgctcctaca actgaaatcg cggtggcaaa
    23101 ggctacgcgt cgatgagcgc gggtcggcag cagcagagct gacggtgttc acgccggtag
    23161 ccgtggcgct gctgttgttc gtcgtgttct gcgggaggct ggccgcgtcc gagatgcggg
    23221 tgaccgacgc cgcgcaccag gccgcgcgct ccgcgtcgat ctcccgaact cctggtcaag
    23281 ccgaccagaa cgcccgcacc accgccgcga ccgcgctcgc ccaagccggg gtgacctgcc
    23341 agaacctcac ggtcgccacc gacacccagg gcctacgccc cggcgccgcg gtcaccgtca
    23401 ccgtgtcgtg cacggtcggc ctgtccgacc tcggcttgct cggcgttcct ggcaaccgca
    23461 cggtcagcgc cacctacacc tccaacatcg acacctaccg cggaacctga ccatgccccc
    23521 acccgccacc ctccgcagac tggccgccaa cgcccaccgg ctgcgtcacg atgaccgcgg
    23581 gcgcgtcacc gcgttcgccg tggtcatggt caacgcctgc ctgttcgtcg ccggcctcgt
    23641 cctcgacggc ggcatcgccc tcaccgccaa ggtcgacgcc ctcggccaag cccaggaagc
    23701 cgcccgagcc ggagcccaac aagtcgacct cggcgcctac cgcggcggcg tactccgcct
    23761 ggacgtcccg cgcgcgaacc aggccgcaca cgacttcctc accgccgcag ggcattccgg
    23821 cacagtgact gtcgccggga accgggtcac cgtgaccgtc accatcaccc gccccaccca
    23881 actcctcggt ctcctcggcg tcgggacggt caccgcgacc gcgaccggca ccgccgaggc
    23941 cgaacgcggc gtcacccgcg ccgacccgta actcaagagg ccacccatga ccaaccggat
    24001 gtccgccctc gcccgcagcg tcgccgccgc cgcggtgctc gcactggtcc tcggcggcct
    24061 gccctgggca ctggcccact acatcggctg gcccctgccc acccag
//
