LOCUS       NZ_CP032698            21056 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces hundungensis strain BH38 chromosome, complete genome.
ACCESSION   NZ_CP032698
VERSION     NZ_CP032698.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces hundungensis
  ORGANISM  Streptomyces hundungensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Relationship between Morphology and Antimicrobial Activity in
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2018) Microbiology and Molecular biology, Chungnam
            National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea,
            Republic of
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: RS HGAP Assembly v. v3.0
            Sequencing Technology             :: PacBio RSII
            Assembly Date                     :: 2018-07-09
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Genome Representation             :: Full
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003627815.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:42:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,472
            CDSs (total)                      :: 7,378
            Genes (coding)                    :: 7,187
            CDSs (with protein)               :: 7,187
            Genes (RNA)                       :: 94
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 191
            CDSs (without protein)            :: 191
            Pseudo Genes (ambiguous residues) :: 0 of 191
            Pseudo Genes (frameshifted)       :: 103 of 191
            Pseudo Genes (incomplete)         :: 121 of 191
            Pseudo Genes (internal stop)      :: 14 of 191
            Pseudo Genes (multiple problems)  :: 42 of 191
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7550030
            Orig. end                         :: 7571086
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032698.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="atropopeptide"
                     /region_number="34"
                     /rules="atropopeptide_p450"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="atropopeptide_p450"
                     /kind="single"
                     /product="atropopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11056](+)"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11056
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="atropopeptide_p450"
                     /neighbourhood="10000"
                     /product="atropopeptide"
                     /protocluster_number="1"
     gene            65..988
                     /locus_tag="DWB77_RS33580"
                     /old_locus_tag="DWB77_06779"
     CDS             65..988
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019619.4"
                     /locus_tag="DWB77_RS33580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06779"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_120726038.1"
                     /transl_table=11
                     /translation="MGWAVLDRLVGEPGLFFEACRRGLPQVFTPAVLPQEVPTLRELTG
                     ALSGGLMRTPYVEMAREGETVPASEFGPAPGAAGGHEQGFADPEQIMALLAEGATLLLP
                     RLDQWNASAGALTALVSQDLRRATEAFCVATMAEHRGPAEHRDDADVLVVQLAGRKEWT
                     VYAVPPEGPRQAGPMPGPGEPALDTVPRRPGPMPGPGEPALDTVIGAGDVLYVPRGAPH
                     TATGDEGLSVHLTLTIRREELRRGPTRPARADLMTAAQLLDTTRELIFAARKRMAAATP
                     EDLLERARGPLPAMPRAASTPRPGVG"
     gene            complement(1033..1872)
                     /locus_tag="DWB77_RS33585"
                     /old_locus_tag="DWB77_06780"
     CDS             complement(1033..1872)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (21-267). E-value: 2e-28.
                     Score: 91.6. Matches aSDomain:
                     nrpspksdomains_DWB77_RS33585_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018382485.1"
                     /locus_tag="DWB77_RS33585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06780"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_120726040.1"
                     /sec_met_domain="PF00561 (E-value: 7.3e-23, bitscore: 80.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 9.9e-17, bitscore:
                     61.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTFSAPDGTPLAYRVTGEGRPLICLPGGPMQASAYLGDLGGLAA
                     DRQLVMLDLRGTGRSAAPQDPASYRCDRLVDDVTALRGHLGLDRVELLAHSAGANLAVS
                     YAARHPETVTRLVLVTPSVFAVGLTIDGELRREMARLRKDEPWFPTAFEALQEITSGRA
                     TDEAWQAISPFFHGRWDERAQAHQAAGDQQKNHEAAAVFGAEGAFDPEATRAALAAFEA
                     PVLLLAGEVDMAAPPRTLAAFAQLFPNAELAVQQGAGHYPWLDDPDAFAATVTAFLG"
     aSDomain        complement(1072..1809)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DWB77_RS33585_Abhydrolase_1.1"
                     /evalue="2.00E-28"
                     /label="DWB77_RS33585_Abhydrolase_1.1"
                     /locus_tag="DWB77_RS33585"
                     /protein_end="267"
                     /protein_start="21"
                     /score="91.6"
                     /tool="antismash"
                     /translation="PLICLPGGPMQASAYLGDLGGLAADRQLVMLDLRGTGRSAAPQDP
                     ASYRCDRLVDDVTALRGHLGLDRVELLAHSAGANLAVSYAARHPETVTRLVLVTPSVFA
                     VGLTIDGELRREMARLRKDEPWFPTAFEALQEITSGRATDEAWQAISPFFHGRWDERAQ
                     AHQAAGDQQKNHEAAAVFGAEGAFDPEATRAALAAFEAPVLLLAGEVDMAAPPRTLAAF
                     AQLFPNAELAVQQGAGHYPWLDDP"
     gene            complement(2000..2248)
                     /locus_tag="DWB77_RS33590"
                     /old_locus_tag="DWB77_06781"
     CDS             complement(2000..2248)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007262001.1"
                     /locus_tag="DWB77_RS33590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06781"
                     /product="chaplin"
                     /protein_id="WP_120726042.1"
                     /transl_table=11
                     /translation="MRIRTALAATVLAATAVIGTAGAAAADPNPPEATGVAQNSPGVLS
                     GDVVQVPIDLGLNVCGDTIDIIGLLNPASNNACGIKQ"
     gene            2455..3087
                     /locus_tag="DWB77_RS33595"
                     /old_locus_tag="DWB77_06782"
     CDS             2455..3087
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS33595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_06782"
                     /product="hypothetical protein"
                     /protein_id="WP_120726044.1"
                     /transl_table=11
                     /translation="MSSGVLIILIAVVVIVVVAVALGVLVARRGRGLRSRFGPEYDRTV
                     AQHHGDVKAAEKDLDERVRRYGDLKVEAPSAEDRRRYAAEWARIQEEFVDSPTRAVADA
                     EALLGRLAQERGFPAGSSEEQLAALSVHHPHHLDSYRRIRGVAQGADGRRSSTEELRET
                     LVQAHEFFAVLSGERRGDKAGRLGARGGRHASHTDTQHSDIARGSQS"
     gene            3084..3860
                     /locus_tag="DWB77_RS33600"
                     /old_locus_tag="DWB77_06783"
     CDS             3084..3860
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS33600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_06783"
                     /product="hypothetical protein"
                     /protein_id="WP_120726046.1"
                     /transl_table=11
                     /translation="MTQPERPLHDETERPLHDQPLAEQPLTGRATPERPANERAVGGRP
                     LDEPSVSERPAQGRAASERPGSAGSVPEAPGSERPLSEPPVSGRPVTERSLSEPSVSER
                     SVSGRSATESPLSDAPHSEGVVPELRTSDQPVAGRSASESAEPGRHLSDHAVPGAGSEP
                     GGSAGNDAVLPPQEREKLQLRLQHAVGGFVDEPRSAVEEAASTVDALTERVLETLEQRR
                     GTLRASWQETSGDAATEDLRMALREYRRLAERLLSL"
     misc_feature    complement(3921..3935)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            3969..4256
                     /locus_tag="DWB77_RS33605"
                     /old_locus_tag="DWB77_06784"
     CDS             3969..4256
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060897.1"
                     /locus_tag="DWB77_RS33605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06784"
                     /product="hypothetical protein"
                     /protein_id="WP_120726048.1"
                     /transl_table=11
                     /translation="MPRRYGGNPAATGILVIADVMALILILWIAFFLVNANTANDIVSW
                     VRHAADWLSGWSRDMFTIKSDTWRTIVNYGMPAVVYLLIGHAVAGRVNRS"
     gene            complement(4243..4800)
                     /locus_tag="DWB77_RS33610"
                     /old_locus_tag="DWB77_06785"
     CDS             complement(4243..4800)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059646.1"
                     /locus_tag="DWB77_RS33610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06785"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_120726050.1"
                     /transl_table=11
                     /translation="MGELVERVDEQDRVLGVVERGDAVRQGWLYRMAMVLCRDAEGRYL
                     VHRRPESAARFPGQYSWLVAGAVGVGESYEEAARRELREELGVDAPVRPLFTFLCDGEL
                     SPYWFAVYEAVVTETDIVADASEVAWHGWLSGDRLREAMANWPFVSDSRDAYTRYLALG
                     SPPDSPGSFDSPGSQGQGVRSD"
     gene            4983..5384
                     /locus_tag="DWB77_RS33615"
                     /old_locus_tag="DWB77_06786"
     CDS             4983..5384
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS33615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_06786"
                     /product="hypothetical protein"
                     /protein_id="WP_120726052.1"
                     /transl_table=11
                     /translation="MRRSATAVAIALCGALAAATAAPAFAADRPPVESAPGAGREVVDG
                     RAGDDDAAGVKSEVAAILKDVNQMVADEKKDAAADVAAAKAEVATLLKQIADMTKADSP
                     QPKPATKPLVDPPAVGAPSTSNPALPTAG"
     misc_feature    complement(5852..5867)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.86"
                     /tool="antismash"
     gene            5885..7360
                     /locus_tag="DWB77_RS33620"
                     /old_locus_tag="DWB77_06787"
     CDS             5885..7360
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (65-231). E-value:
                     5.8e-16. Score: 50.3. Matches aSDomain:
                     nrpspksdomains_DWB77_RS33620_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1209: polyketide synthase associated protein papA3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029681.1"
                     /locus_tag="DWB77_RS33620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06787"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_120726054.1"
                     /sec_met_domain="Condensation (E-value: 1.7e-10, bitscore:
                     39.2, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRITDIHGCEVRPGRLVEWSLDPAMVEAATNQPDDSRPPAYVQES
                     HIRTARSVREDGLFVPTWLGAAFDIPGPVDLDVLEGALRTWTVRHETLRSGFRWVDDDM
                     RRFTAAPDAVALRREVVGDFPDAEELSHHLQDRFDVAADALGWPNFLYTAVVRPDSTSV
                     YMAFDHSNVDAYSIQRIPSEIHELYSARAAGGGEEATPVGSYVDFCEIERASADQVDDT
                     HAIVARWREFIARCDGRLPAFPVDLGLEPGGRLPEQKLMYETLVDDADAAAFSAYCRPF
                     GGGQVGILAATSLIVHDIGGEPVYRTVVPLHTRAKSRWADSVGWYVGGAPIEIPVAQAL
                     GFDDALTMVHGALRANKALAHLPIARVLRLLGSDFRPTSPDLYSIVSFVDARDIPGARQ
                     WDELHAYALLRVSYGDQVCAWFTRLHGGLQLAIRYPDTAIAHKNIHRYVEQLRELITSV
                     ARRGPTRPVPPRPRAGRPVPAPRVSSEVSRLSL"
     misc_feature    complement(5923..5936)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.8"
                     /tool="antismash"
     CDS_motif       6080..6181
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DWB77_RS33620_0001"
                     /evalue="2.10E-08"
                     /label="C2_DCL_024-062"
                     /locus_tag="DWB77_RS33620"
                     /protein_end="99"
                     /protein_start="65"
                     /score="26.4"
                     /tool="antismash"
                     /translation="AAFDIPGPVDLDVLEGALRTWTVRHETLRSGFRW"
     aSDomain        6080..6577
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DWB77_RS33620_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.80E-16"
                     /label="DWB77_RS33620_Condensation_LCL.1"
                     /locus_tag="DWB77_RS33620"
                     /protein_end="231"
                     /protein_start="65"
                     /score="50.3"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DHSNVDA"
                     /tool="antismash"
                     /translation="AAFDIPGPVDLDVLEGALRTWTVRHETLRSGFRWVDDDMRRFTAA
                     PDAVALRREVVGDFPDAEELSHHLQDRFDVAADALGWPNFLYTAVVRPDSTSVYMAFDH
                     SNVDAYSIQRIPSEIHELYSARAAGGGEEATPVGSYVDFCEIERASADQVDDTHAIVAR
                     WRE"
     misc_feature    7403..7417
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.44"
                     /tool="antismash"
     gene            7444..8430
                     /locus_tag="DWB77_RS33625"
                     /old_locus_tag="DWB77_06788"
     CDS             7444..8430
                     /NRPS_PKS="Domain: Abhydrolase_1 (83-217). E-value:
                     1.8e-09. Score: 29.5. Matches aSDomain:
                     nrpspksdomains_DWB77_RS33625_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1104: putative esterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330720.1"
                     /locus_tag="DWB77_RS33625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06788"
                     /product="alpha/beta hydrolase family protein"
                     /protein_id="WP_120726056.1"
                     /sec_met_domain="PF00561 (E-value: 1.1e-05, bitscore: 24.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRPSIITCVMVLLLTLLAGAFTMGPAGAWDRPVRADDGARVVAE
                     RRLGPREMDLTIQSPALGSIAQVRLLTPDGWSPGRHAWPVLWLLHGCCGGYADWTTYSD
                     VAQLPALRQVLVVMPEAGAAGWYSDWWNYGRGGAPRWEEFHLGEVRQIVERGYGAGERR
                     VAAGLSMGGFGALLYAARHPGFFRAVASYSGTVHPLLQVPGGFGPDWFLDLDRGAGVDP
                     YAIWGDPAEQRAVWAAHDPTLRAGPLRGLPVFLSCGDGRAGPYDPPGTTDPGETYLERQ
                     NQALAARLRALGSPAVTDFYGPGHHDWPYWQRELRRSLPMLLAALRA"
     aSDomain        7693..8094
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DWB77_RS33625_Abhydrolase_1.1"
                     /evalue="1.80E-09"
                     /label="DWB77_RS33625_Abhydrolase_1.1"
                     /locus_tag="DWB77_RS33625"
                     /protein_end="217"
                     /protein_start="83"
                     /score="29.5"
                     /tool="antismash"
                     /translation="PVLWLLHGCCGGYADWTTYSDVAQLPALRQVLVVMPEAGAAGWYS
                     DWWNYGRGGAPRWEEFHLGEVRQIVERGYGAGERRVAAGLSMGGFGALLYAARHPGFFR
                     AVASYSGTVHPLLQVPGGFGPDWFLDLDRG"
     gene            complement(8494..8925)
                     /locus_tag="DWB77_RS33630"
                     /old_locus_tag="DWB77_06789"
     CDS             complement(8494..8925)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS33630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_06789"
                     /product="hypothetical protein"
                     /protein_id="WP_162952660.1"
                     /transl_table=11
                     /translation="MNTSTEPPSRPRTLQAGHVVAIGALLSAAALVERVPRFASGHRYL
                     LCHTSSTLDHLTLAALALVLAAGVAALAGAIMMQAKDTHGAALPVVWLVVVVVLVVAAD
                     GVDAHGEAIAAHLSATPFTEGACNYVPQDYVATPGWFFW"
     gene            complement(8966..9355)
                     /locus_tag="DWB77_RS33635"
                     /old_locus_tag="DWB77_06790"
     CDS             complement(8966..9355)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977879.1"
                     /locus_tag="DWB77_RS33635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06790"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_120726060.1"
                     /transl_table=11
                     /translation="MVSDRADVTVAERFLGAFGSHDWESLRTVLAPDLVWSMPGTGSIS
                     GTIHGVDAAIDRLRTIAARGLNTELLHVLTGANGVTLSLHNTARDADGRTLDEHLATVL
                     TLREGKVAAIDSYVSDVDGMSGFFN"
     misc_feature    9664..9679
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.17"
                     /tool="antismash"
     misc_feature    complement(9711..9724)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.3"
                     /tool="antismash"
     gene            10001..11056
                     /locus_tag="DWB77_RS33640"
                     /old_locus_tag="DWB77_06791"
     CDS             10001..11056
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     atropopeptide: atropopeptide_p450"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (MITE)
                     MITE0000172: Biaryl bond formation (67% identity)"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265664.1"
                     /locus_tag="DWB77_RS33640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06791"
                     /product="cytochrome P450"
                     /protein_id="WP_246033713.1"
                     /sec_met_domain="atropopeptide_p450 (E-value: 1.7e-180,
                     bitscore: 598.3, seeds: 287, tool: rule-based-clusters)"
                     /sec_met_domain="p450 (E-value: 1.4e-12, bitscore: 45.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTRRTTVFAPRLQALLDEHLGKDLVRLEPDTIGIAGAELSDRI
                     LSARRATETERPTFKPLHGRSISKAEASSVMRTIGKDVRAALEQPDPLPDTTDLSGPWP
                     ITGHRFLSRLVLRDDPYRLRILMSRTLEIDPRLTWTTIVAGAALPRRPAPGPQLTHLAN
                     LFAEAGTYHDRRYAMGIYRRAAAPVCFTVSTLVANALWLGAPFADDASNRDILYEAMRL
                     LPPSWNLLRNRSAEYPAIDDRIGHEDDILMLPLLTHRDPALWEAPNEFRPERWEGLDPD
                     NTPGYMPFGHVSERCWGRHMVMPLAELLLDHIRRTGLVVAPGQRTAEVPLVGLLGVKTV
                     HLGHRSKVRHG"
     gene            11049..12266
                     /locus_tag="DWB77_RS33645"
                     /old_locus_tag="DWB77_06792"
     CDS             11049..12266
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004936894.1"
                     /locus_tag="DWB77_RS33645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06792"
                     /product="cytochrome P450"
                     /protein_id="WP_120726064.1"
                     /sec_met_domain="p450 (E-value: 9.9e-23, bitscore: 79.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADVETPDASFFDHPHAVYRRWREEGGTRQVRYPGPAPVEGWVVT
                     SHAEAKRLLADPRLAKGGAVERFGRHTGLTRGPGSALFAHMLNSDPPHHTRLRKLVQKA
                     FTARRTAALRPLIEARVTGLLDAWEGRDEVELISEFALPLPMAVMFDLFGASDADHEVL
                     RVRGNTLDGGQGDGEVSVFTAESMLTYLRALLALKREQPDDGLLSALVAAGDEGAEGTE
                     GEEALSEDEITSMAFLLVIAGHQTTVNLIANGVHALLTHPEQLAALQADMTLMPGAVEE
                     ILRYESPSALASLRYAAEPVGVGEATVREGEFVQISLLGANRDPGVFAEPDRFDIRRAD
                     AARHLAFGHGIHHCLGAPLARLQAEIAFSHLLTRHPGLRLSEDHEARWQANPRHRGLLS
                     LPLRLT"
     gene            complement(12292..12951)
                     /locus_tag="DWB77_RS33650"
                     /old_locus_tag="DWB77_06793"
     CDS             complement(12292..12951)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130107.1"
                     /locus_tag="DWB77_RS33650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06793"
                     /product="hypothetical protein"
                     /protein_id="WP_120726066.1"
                     /transl_table=11
                     /translation="MVHPGSTPVPSQPRRRGGCLPALVILLVILGLGFGASKFFGSDGK
                     KSSSSSSSSSSSHDKGEWKVGDCGGPDPDDAPNGYKAFDCGASGATFKALDIQAASFMP
                     DSIQCPGGTDLIIQVSISYGSSKSKGGGIPSKTVCGRNLSANHPGDPGAGGGQLVKGDC
                     VTSTAKEVSCASSGSGAYKVLDLTKQTSQCPSGTTEPMRLTMAIGRPYDVICAAKQ"
     gene            complement(13081..14439)
                     /locus_tag="DWB77_RS33655"
                     /old_locus_tag="DWB77_06794"
     CDS             complement(13081..14439)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="DWB77_RS33655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06794"
                     /product="cytochrome P450"
                     /protein_id="WP_162952661.1"
                     /sec_met_domain="p450 (E-value: 9.1e-75, bitscore: 250.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKLPSRTGKAPGAWPLLGHAWQLHSRPLEFLSSLPAYGDLVRI
                     GMGPWPAYVVCEPEAAHRMLTDSRTFDKGGPFFDKARVLFGSSLPMAGWQEHRWQRRQM
                     QPAFQSDRIEKYAVVMGEEVDRMTTRWRPGLRLDVTDALTTLTLRIVTRSVLGAEAQDE
                     AVAEVQQSLHTVIDGIYQRVMLPLGPLYRLPTAANRRYRRACDRLHHAIDGIIAARRAA
                     PGGDDLVSMLLTATNDDTGAPMSDVDIRDQLMVMIGAGFETTANSLAFALWLLSQHPDV
                     EARVHDEVDATLAGRTATTADLDGLIHTRRVINEVLRLYPAGWFFTRVTTTDTTLAGRQ
                     LPKGTALLYSAYLLQRRPELFPDPERFDPDRWDTRPAESLPRGTHVPFGGGNRKCIGDQ
                     FALIEMTLALATVCARWRLVPDPGSTMTVRVRGTLGPGPLTMTCQPRGKSAEG"
     gene            complement(14650..16197)
                     /locus_tag="DWB77_RS33660"
                     /old_locus_tag="DWB77_06795"
     CDS             complement(14650..16197)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005310580.1"
                     /locus_tag="DWB77_RS33660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06795"
                     /product="MFS transporter"
                     /protein_id="WP_120726070.1"
                     /transl_table=11
                     /translation="MTSSQPAPKVETAPPSGGGGGNGIALLVIAACQLMVVLDITIVNI
                     ALPHIQSALHFSTTSLAWVVSAYTLTFGGLLLLGGRAGDILGRRRVFMCGVLLFALASL
                     FGGLSQNAGQLLAARAVQGVGGAIASPTALALITTTFTEGPARNRAFGVFAAVSAGGSA
                     IGLLAGGVLVEWLDWRWVLFVNVPIAVLILLATPRHIKESERHAGHFDIAGATTSTLGM
                     VALVYGFIRAAQEGWRDPFTLGSFAAAVVLLSAFVLVERRSQQPITPLHMFADRNRAGT
                     YGMMLSLSAAIFGMFFFLTLFVQDVLGFSALQAGLAFLPVSAIIAVGAGLTSQLLPKYG
                     PKPFMVTGAILAAGGLSWLTQTDIHSTYPGSILGPLLVFGLGMGLNFVSLTLMAVSGVP
                     PHEAGAASGMLNVTQQVGGSLGLSILVTVFGTAGRNEARDQIPKFLGQADPAQRLMFRR
                     TGQLPRPWSDQVLTSGVSMAFVVAAIFAVIAALIAVLAIQVRPSDLERLQGAGPPHS"
     gene            complement(16436..17212)
                     /locus_tag="DWB77_RS33665"
                     /old_locus_tag="DWB77_06796"
     CDS             complement(16436..17212)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010269022.1"
                     /locus_tag="DWB77_RS33665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06796"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_120726072.1"
                     /transl_table=11
                     /translation="MWAGRAQAYASSFAGVCAHPVPQLLDAARVGAGVRVLDVGTGTGT
                     VAEAACARGAGVTGVDAEVDMVDWAARAVPQAAIQLAVLPQLPFADGFFDAVTANFVLD
                     HVGRPGAAIAELRRVVRPGGRIAVTLWAVPEAAGQSLLGRAVRAAGVTLPSGLSAPAAE
                     DDFPRTVPGLAGLLTSSGLRDVTCEPVHWEHRVPADTWWAGAAAGLGTVGQVVASRPER
                     IRAEIRRHFDLLSAEFTIGRGELALPHSALLACGHR"
     misc_feature    17220..17233
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.64"
                     /tool="antismash"
     gene            complement(17494..17721)
                     /locus_tag="DWB77_RS33670"
                     /old_locus_tag="DWB77_06797"
     CDS             complement(17494..17721)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059185.1"
                     /locus_tag="DWB77_RS33670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06797"
                     /product="DUF5133 domain-containing protein"
                     /protein_id="WP_120726074.1"
                     /transl_table=11
                     /translation="MLMAHPAVLRDLLDEYEALLVLNAAEGDEATRQRLDDVTYTLCVS
                     TGTRDIDAAVIAARHRLPGARTFDDSVLTA"
     gene            complement(17871..18869)
                     /locus_tag="DWB77_RS33675"
                     /old_locus_tag="DWB77_06798"
     CDS             complement(17871..18869)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019883934.1"
                     /locus_tag="DWB77_RS33675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06798"
                     /product="xanthine dehydrogenase family protein subunit M"
                     /protein_id="WP_120726076.1"
                     /transl_table=11
                     /translation="MKPVAYVRPRNLAEAAAAHGGRPEARYLGGGTNLVDLMRLGVERP
                     DLLVDITRLPLDAIEEQPDGSVRVGATVRNSDLATHPALRDRYPVLPQALLSGASGQLR
                     NMATTAGNLLQRTRCGYFQDLSRPCNKRVPGSGCGAIEGVNREHAVFGHSSLCVATHPS
                     DLAVALAALDALVELEGPGGTRAVPVTEFYRLPQDRPEVDTVMRPGEIVTAVVVPSAPE
                     GSVSRYRKARDRAGHTFALASVAALVHLERGVVREVALAFGGLAHRPWRARRTEAALLG
                     TAPTAETIERAVDAELADAVPLRHNAYKVELARGLAREVLESLAQVRPAGR"
     gene            complement(18866..19456)
                     /locus_tag="DWB77_RS33680"
                     /old_locus_tag="DWB77_06799"
     CDS             complement(18866..19456)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062177.1"
                     /locus_tag="DWB77_RS33680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06799"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_246033714.1"
                     /transl_table=11
                     /translation="MEARHGRQERRPGLVTRVFGHGVTDSHVTLRVNDAEHRVELEHCA
                     TLLEVLRENLGLTASRKGCDDGRCGECTVLLDGRRVNSCLLLAVAQEGREIVTVEGLVA
                     ADADDDRHPLRRAVVDRDVVQCAYCAPDQHRSAAAGSAGAPSGPSSVVTDIDLPPDAPV
                     RLTAAEVRDRLSGNLCRCGAYPSGAEAVQDVIV"
     gene            complement(19646..20077)
                     /locus_tag="DWB77_RS33685"
                     /old_locus_tag="DWB77_06800"
     CDS             complement(19646..20077)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541082.1"
                     /locus_tag="DWB77_RS33685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06800"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_120726078.1"
                     /transl_table=11
                     /translation="METAERFRAAVEKRDVSALEGLFTEDVRLYSPVKFVPFEGRAMVL
                     GLFGVLVRVFEDLRYLGRLDGAAETSADGEEAPSVVLPFRATVAGKQIHGIDLLQFDEA
                     GLIKEFTVMVRPQSAVHALGQAVLAGLVADDLAPAPAEG"
     misc_feature    complement(20084..20098)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.62"
                     /tool="antismash"
     gene            20168..20737
                     /locus_tag="DWB77_RS33690"
                     /old_locus_tag="DWB77_06801"
     CDS             20168..20737
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174164.1"
                     /locus_tag="DWB77_RS33690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06801"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_120726080.1"
                     /transl_table=11
                     /translation="MALRHAVLAALLDGEFSGYQLAKAFDIGVANFWHALPQQLYAELA
                     KLEKDGLVAGRQVVQETRPNKRLFHVTDAGRAELETFAAATAKPSFIRDDLLVKVQAAD
                     RIGTAPVIGQLEERAAAADAKIELLGALLRQLRGDRDEDDFLLHGERIGPYLTCLRGLA
                     FEREHRDWCRRIAAVLRERHRADAER"
ORIGIN
        1 gctgcggctc ccgtaggttc gggtgcgagg cggtgccgta ccgccccgga cctggggaga
       61 gacgatgggt tgggcagtgc tggaccggct cgtgggggag cccgggctgt tcttcgaggc
      121 atgccgtcga gggctacccc aggtgttcac ccccgccgtg ctgccccaag aggtgcccac
      181 gctgcgcgag ttgaccgggg cgctgagcgg cggtctgatg cggacgccgt acgtcgagat
      241 ggcgcgggag ggcgagacgg tgccggcgtc ggagttcggc cccgcccccg gcgccgcggg
      301 cggacacgag cagggcttcg ccgaccccga gcagatcatg gccctgctcg ccgagggggc
      361 gacgctgctg ttgccccgac tcgaccagtg gaacgcctcg gcgggcgccc tgaccgcact
      421 cgtctcacag gacctgcggc gcgcgacgga agcgttctgc gtcgcgacca tggcggaaca
      481 ccgcgggccc gctgagcacc gcgacgacgc cgatgtcctg gtcgtgcagc tcgcgggccg
      541 caaggaatgg acggtgtacg ccgtcccgcc cgagggcccc cggcaggcgg gcccgatgcc
      601 cgggccgggc gagcccgcgc tggacaccgt gccccggcgg ccgggcccga tgcccgggcc
      661 gggcgaaccg gcgctggaca ccgtcatcgg cgcgggcgac gtcctttatg tgccgcgcgg
      721 cgcgccccac accgcgaccg gcgacgaggg cctctccgtc cacctcaccc tcaccatccg
      781 ccgtgaggag ctccgtcgag gcccgacgcg tccggctcgt gccgacctca tgacagcggc
      841 ccaactactc gacaccaccc gcgagttgat cttcgcggcg cgcaagcgga tggctgcggc
      901 cacccccgag gatctcctgg agcgggcgcg cggcccactg ccggccatgc ccagggccgc
      961 gtccaccccg cgaccgggcg tcggctgaac cggagcctgc ccaggaagcc gccgcggtcc
     1021 cggccgactc cgctagccga ggaacgccgt gacggtggcg gcgaacgcgt ccgggtcgtc
     1081 gagccagggg tagtggccgg cgccctgctg tacggccagt tcggcgttgg ggaacagctg
     1141 ggcgaacgcg gcgagcgtgc gaggcggcgc cgccatgtcc acctccccgg cgagcagcag
     1201 caccggcgcc tcgaacgcgg cgagcgccgc ccgggtggcc tccgggtcga aggctccctc
     1261 cgcgccgaag acggccgccg cctcgtggtt cttctgctgg tccccggcgg cctggtgcgc
     1321 ctgtgcccgc tcgtcccaac gaccgtggaa gaagggcgag atcgcctgcc aggcctcgtc
     1381 cgtcgcccgg cccgacgtga tctcctgaag cgcctcgaaa gccgtgggga accagggttc
     1441 gtccttgcgg agccgtgcca tctcgcggcg cagctccccg tcgatcgtga gcccgacggc
     1501 gaagacgctc ggagtgacca ggaccagcct ggttacggtt tccggatgcc gggcggcgta
     1561 cgacaccgcg agattcgcgc ccgcggaatg agcgagcagc tccacccggt ccaggccgag
     1621 gtggccgcgc agcgcggtca catcgtcgac gagacggtcg cagcggtagg aagcggggtc
     1681 ctggggcgcc gcggaccggc cggtgccccg caggtccagc atcaccagct gccggtcggc
     1741 cgcgagaccg ccgaggtccc ccaggtatgc ggaggcctgc atcgggcctc cgggcaggca
     1801 gatcaaaggg cgaccctcgc cggtgacccg gtaggcgagc ggggttccgt cgggcgcgga
     1861 gaaagtgggc atgggccaga ccctgacagt gcgtcgtcgc cgggtcaatc cccttcctga
     1921 cctgcgggga cggcgcgcct gcgccccgga gccagggatc ggctccgggg cgcagacgtg
     1981 ggacgggtgc ggcggactac tactgcttga tgccgcaggc gttgttggag gccgggttga
     2041 gcagcccgat gatgtcgatg gtgtcgccgc acacgttgag accaaggtcg atggggacct
     2101 ggacgacgtc gccggagagc acacccgggg agttctgggc cacgccggtg gcctccggcg
     2161 ggttggggtc ggcggcggcg gcgccggccg tgcctatgac ggcggtggcg gccaggacgg
     2221 ttgcagcgag tgcggtacgg atacgcacga ttcctcctgt gtgtgagggt ttgtctccct
     2281 agcagcgtct ccggggtcgg gccgaagggg aaatcccgtg acccgatggg gtgaacgaag
     2341 ccgagcggct gtgcgcggac attccgtcat tggcgcgttt attcggccgc ttcgcgcgta
     2401 ctcgcagagg tacagcccag agtgcggggc cgttcaccga cggaaaggca ggccatgtcc
     2461 agtggtgtcc tcatcatcct gatagcggtc gtggtgatcg ttgtcgtggc agtggctctc
     2521 ggcgtgctcg tcgcgcgccg cgggcgggga ctgcgcagcc gtttcggacc cgagtacgac
     2581 cggaccgtcg cccagcacca tggcgacgtc aaggccgccg agaaggacct tgacgagcgg
     2641 gtccgccgct acggcgacct gaaggtggag gccccgtccg cggaggaccg ccgccggtac
     2701 gccgccgaat gggcccggat ccaggaggag ttcgtggatt cgccgacgcg cgcggtcgcc
     2761 gacgccgagg ctctgctcgg ccggctcgcg caggagcgcg gcttcccggc cggctcctcc
     2821 gaggagcagc tggccgccct ctcggtgcac cacccccatc acctcgacag ctaccgccgg
     2881 attcgcggcg tggcgcaggg tgccgacggg cgcaggtcca gcaccgagga actccgcgag
     2941 acgctcgtac aggcccatga gttcttcgcg gtcctgtccg gcgagcgccg cggcgacaag
     3001 gccggacgcc tcggggcacg cggcggccga cacgcgtccc acaccgacac gcagcacagc
     3061 gacatcgccc gagggagcca gtcatgaccc agcccgagcg tccccttcac gacgagaccg
     3121 agcgtcccct tcacgatcag cccctggccg agcagcccct gaccggccgc gccacgccgg
     3181 aacggcccgc gaacgagcgt gccgtcgggg gccggcccct tgacgagccc tcggtgtccg
     3241 agcggcccgc gcagggacgg gccgcgtccg agcggcccgg gtccgcgggg tccgtgccgg
     3301 aggcacccgg gtccgaacgg ccgctgtccg agccccctgt atcgggtcgg ccggtgaccg
     3361 aacggtcctt gtccgaaccg tccgtgtccg aacgatccgt gtcggggcgg tcggcgaccg
     3421 agtcgccgct gtccgacgcg ccgcactccg agggcgtcgt gcccgagctg cggacgtccg
     3481 atcagccggt ggctgggcgg tcggcgtccg aatcggccga gcccgggcgg cacctctccg
     3541 atcacgcggt gccgggcgcc ggctcggaac cgggcgggtc ggccggaaac gacgccgttc
     3601 tgccgcccca ggagcgcgag aagttgcagc tcaggcttca gcacgcggtc ggcgggttcg
     3661 tggacgagcc ccgttcggcg gtcgaggaag ccgcctcgac ggtcgacgcc ctcaccgagc
     3721 gggtcctcga aactctcgaa cagcggcgcg gcaccctgcg cgcgtcctgg caggagacgt
     3781 ccggcgacgc ggccacggag gatctgcgca tggctctgcg ggagtaccgc cggctcgcgg
     3841 aacgtctgct cagcctgtga agccccacac cccccgagcc ccggagggcg ccctgacggc
     3901 gcccccgggg cgcaccgcgc atccacaccc cagatcctca acccgcccgt acagacaagg
     3961 agttggacat gcccaggcgc tatggcggta atcccgccgc gaccggcatc ctcgtcatcg
     4021 ccgatgtcat ggccctgatc ctgatcctct ggatcgcctt cttcctggtc aacgccaaca
     4081 cggcgaacga catcgtctcg tgggtccgtc acgcggcgga ctggctctcg ggctggtcgc
     4141 gagacatgtt caccatcaag tccgacacct ggcgcacgat cgtcaactac ggcatgcctg
     4201 ccgtggtcta cctcctgatc ggccatgcgg tggccggccg ggtcaatcgc tcctgacccc
     4261 ttggccttgc gagccgggtg agtcgaacga gccgggtgag tcgggcggcg agccgagagc
     4321 gaggtagcgg gtgtaggcgt cccggctgtc ggagacgaac ggccagttcg ccatggcctc
     4381 cctcagccgg tcgccgctca gccagccgtg ccaggcgacc tccgacgcgt ccgccacgat
     4441 gtccgtctcc gtcacgaccg cctcgtacac cgcgaaccag taagggctga gctcgccgtc
     4501 gcacaggaac gtgaacaggg ggcgaaccgg tgcgtccacc cccagttcct cgcgaagctc
     4561 ccggcgagcc gcttcctcgt aggactcgcc cacccccacg gccccggcca ccagccagct
     4621 gtactggccg gggaaccgtg cggcggactc cgggcgccgg tgcaccagat agcggccctc
     4681 cgcatcgcgg cacagcacca tggccatccg gtacagccag ccctggcgta ccgcatcgcc
     4741 ccgctcgacc acaccgagca cacgatcctg ttcgtcgacg cgttccacca gttcacccat
     4801 gggtcaatcc tccatgaagg cgatccgcat atgtggggcg cccccagtac gtgctctccg
     4861 acgctgcgtc aggtccgcct cactcgttcg gaaggccccg ctggccctcc gggcgtgggt
     4921 ggcgaagagt ggatcgagag tggggggcga cttggatgcc gtcgaacgtg aggagcgcga
     4981 tcatgcgccg tagtgccacc gccgtcgcga tcgccctgtg cggcgcactc gccgcagcta
     5041 ccgcggcccc cgccttcgcc gccgaccggc cgcccgtcga gtccgccccc ggggcgggac
     5101 gcgaggtggt ggacggacgg gccggggacg atgacgccgc gggtgtcaag agcgaagtgg
     5161 cggcgatcct gaaggacgtc aaccagatgg tcgcggacga gaagaaggac gcggccgcgg
     5221 acgtggcggc cgccaaggcc gaggtggcca ccctcctcaa gcagatcgcc gacatgacca
     5281 aggcggactc gccgcagccg aagccggcga ccaagccact cgtcgacccg cccgcggtcg
     5341 gcgcgccgtc gacctccaac ccggcgctcc ccacagcggg ctgacgcctc gatcggacca
     5401 cgatcacgcg atacgaacag tcggttgtcg atcgcggcgg gcctcaaaac ccgtgctgat
     5461 acggcgagtt cagaagagcc gccccctagg tcgacggcag ggggcggctt cgtcgcgcac
     5521 ggcgcacggt ggcgtgtggg gcgggcgcat ccgactcgat ggggtggttt cgcgtgcccg
     5581 gagcgcacgt ctcgcgttgg tcaccacatg accgtatttc ctgggttgcg gtgcacggcg
     5641 accgcccccc gccccgtgat gtcgcgaacg ggcgccccac gtaagggcgt tgtgatcgag
     5701 gaatccgaag gattcggcgg gatgcctcac catgccagcg cttctccggg ccgctcgccc
     5761 tgctcggccg accgccgtga ggtgctgtgg cagaccggcg gcgggccttc ccgcccggcc
     5821 ggaccagccc ctgcggcccg ccgctcgccc gtgttcccca acagcttgtg aatggaaaac
     5881 tcccgtgcga atcaccgaca ttcacggctg tgaggtccgt cccggacgtt tggtcgagtg
     5941 gagcctggat cccgccatgg tcgaggccgc gaccaaccag cccgacgact cacgcccccc
     6001 tgcctatgtg caggaatcac atatccgcac cgcccggtcc gtgcgcgagg acggactgtt
     6061 cgtgccgacg tggctgggcg ccgccttcga catccccggg cccgtcgatc tcgacgtcct
     6121 ggaaggggcg ctgcggacct ggacggtccg gcacgagacg ctccgcagcg gcttccgctg
     6181 ggtcgacgac gacatgcgcc gcttcaccgc cgcgccggac gccgtggcac tgcggcgcga
     6241 agtcgtgggc gacttccccg acgcggaaga actgagccac cacttgcagg accgtttcga
     6301 tgtggcggcg gacgcgctgg gctggccgaa cttcctgtac accgcggtcg tccggccgga
     6361 ctccaccagc gtgtacatgg ccttcgacca cagcaacgtc gacgcgtact cgatccagcg
     6421 catcccctcc gagatccacg agctgtactc ggcgcgggcg gccgggggcg gcgaggaggc
     6481 gacaccggtc ggcagctatg tcgacttctg cgagatcgag cgggccagcg ccgaccaggt
     6541 cgacgacacc cacgcgatcg tggcgcgctg gcgggagttc atcgcccgct gcgacggccg
     6601 actgccggcc ttcccggtcg acctcggcct cgaacccgga ggcagactgc ccgagcagaa
     6661 gctcatgtac gaaacgctcg tggacgacgc ggacgccgcc gccttctcgg cgtactgccg
     6721 gcccttcggc ggcggccagg tgggcatcct ggcggccacc agcctcatcg tccacgacat
     6781 cgggggcgaa ccggtctacc gcacggtggt gccgctccac accagggcga agtcccggtg
     6841 ggcggactcg gtgggctggt acgtcggcgg ggcccccatc gagatcccgg tggcccaggc
     6901 gctgggcttc gacgacgcgc tgacgatggt ccacggcgcc ctgcgggcga acaaggcgct
     6961 cgcccatctg ccgatcgccc gtgtgctgcg gctgctcggc tcggacttcc gccccacctc
     7021 ccccgacctc tactcgatcg tgtcgttcgt cgacgcgcgc gacatccccg gggcccggca
     7081 gtgggacgag ctccatgcct acgccctgct cagggtgtcc tacggggacc aggtgtgcgc
     7141 gtggttcacc cgcctgcacg gcgggctgca actcgccatc cgctacccgg acacggcgat
     7201 cgcacacaag aacatccacc gctatgtgga acagctgcgg gaactcatca cctccgtcgc
     7261 ccgccggggc ccgacccgac ccgtaccccc gagaccgcgt gccgggcgcc cggtgccggc
     7321 gccgagggtg agcagcgagg tctcccggct gtcgctctga gaccgggcgg tccgaagggt
     7381 gcatgctggc ccacatgtgg cttcaccaca tgtgggcctc acccatagga caaaggggtc
     7441 gcgatgcgtc gcccgtcgat catcacgtgt gtcatggtcc ttctgctcac cctgttggcc
     7501 ggagccttca ccatgggccc ggccggcgcg tgggaccggc ccgtacgcgc cgacgacggg
     7561 gcccgggtgg tcgcggagcg gcgcctcgga ccgcgcgaaa tggatctgac catccagtcc
     7621 ccggccctgg ggtcgattgc ccaggtgcgt ctgctcaccc cggacggctg gtcaccggga
     7681 cggcacgcgt ggccggtgct gtggctgctg cacggctgct gtggcggcta cgccgactgg
     7741 acgacctaca gtgatgtggc ccaactcccg gcgctacgcc aggtgttggt ggtcatgcca
     7801 gaggccggcg cggcgggctg gtacagcgac tggtggaact acggcagggg cggcgctccc
     7861 cgctgggagg agttccatct cggcgaggtc cgacagatcg tcgaacgggg ctatggtgcg
     7921 ggcgagcgcc gagtggcggc gggtctgtcg atgggaggct tcggcgcact gctgtacgcg
     7981 gcgcgccacc cggggttctt ccgggcggtc gcgtcctaca gcggcaccgt gcatccgctg
     8041 ctccaggtgc ccggcgggtt cggccccgac tggttcctgg acctcgaccg gggcgcgggc
     8101 gtcgacccgt acgccatctg gggagacccg gccgagcagc gcgcggtgtg ggccgcgcac
     8161 gaccccactc tccgggccgg cccgctgcgc gggcttcccg tcttcctgtc ctgcggggac
     8221 ggccgggccg gaccctacga tccgcccggc acgacggatc cgggcgagac ctacctggag
     8281 cggcagaacc aggccctcgc cgcccggctg cgtgccctcg gcagcccggc cgtcaccgac
     8341 ttctatgggc cgggacacca tgattggccg tactggcaac gggagttgcg tcgctccctg
     8401 ccgatgctgc tggccgcgct ccgcgcctga tcacctgagg gccgccgagg agtgtggtcc
     8461 tgacccggtc cacggggtac gggccacggc cggctaccag aagaaccagc ccggcgtcgc
     8521 tacatagtcc tgcggaacat agttacaggc gccttcggtg aacggtgtgg ccgacaggtg
     8581 tgccgcaatc gcctcgccat gggcgtcgac cccgtccgcc gccaccacca ggacgaccac
     8641 gacgacgagc cacaccacgg gaagggccgc gccgtgggtg tccttcgcct gcatcatgat
     8701 cgcgccggcc agggccgcca cgcccgccgc cagcaccagg gcgagagcgg cgagagtcag
     8761 atggtccagg gtcgacgagg tgtggcacag cagataccgg tgcccggagg cgaaccgcgg
     8821 cacccgttcc acgagggcgg ccgcagacag cagcgccccg atcgcgacca cgtggccggc
     8881 ctgcaacgtc cttggcctgc tgggtggttc agtgctggtg ttcatggtcc ccccgggccc
     8941 ggtcggcgtg atgcggagcc actgcctagt tgaagaagcc gctcatgccg tccacgtcgg
     9001 agacatagct gtcgatcgcg gcgaccttcc cctcgcggag ggtgagcacg gtcgccagat
     9061 gttcgtcgag cgtgcggccg tcggcgtcgc gcgcggtgtt gtgcagcgac agggtgacgc
     9121 cgttcgcgcc cgtcaggacg tggagcagct cggtgttcaa gccccgggcg gcgatggtcc
     9181 gaagccggtc gatggcggcg tcgacgccgt ggatggtgcc ggagatggat ccggtgccgg
     9241 gcatgctcca gacgagatcg ggcgccagga ccgtacggag ggactcccag tcgtgggagc
     9301 cgaaggcgcc gagaaatcgt tcggccacgg tcacatcggc tctgtcgctc accatggtgt
     9361 cgcactctcc tgtgtcgggg gccaccggtc cctggttcgt ccggcggccg cggatgatcg
     9421 cggtttcccc gacgatagag ggtccgtccg gcgccgccgc gcccggagcg cctccgagca
     9481 ccgcgccacc gcattgcctt gccgaagggc cgcgttgcta gcaggtcgcg tatcggcccc
     9541 gaaaggtatg cccgggcaat ggcccatgac cgttcgggca ggccttcccg aatcgccaca
     9601 atgaatgttt cgaagggctc cacatgaact caagaactca cagggacaaa cgaatgcgga
     9661 accattgaca acgcttgtcg tggccagctt cacttcctct caacggccgg ttacacactt
     9721 tccacacacc cccaaggtga gtgaattggc gtgtcccgtc cggcagttca ttccgtatat
     9781 ccgtgagagg aagggattga cgatggcgaa gatcattgcc gcactgcgta cccgtggatc
     9841 gaagagcgag ccgagcctga agcaggccgc ctggtacttc tggtactaag tcgaaggcca
     9901 atcctgggcc cgcacacaaa gcaaaccgac tgaattccgg tcagccgcgt gtgcgggccc
     9961 tccgcatttc atttccggag ctcttcgtat gccatccgcc atgacccgca ccaggcgcac
    10021 cacggttttc gccccccgac tacaggctct cctcgacgaa cacctcggca aggatctcgt
    10081 ccgcctcgaa cccgacacca tcggcatcgc cggcgcggaa ctctccgacc gcatcctgag
    10141 tgcgcgccgg gcgacggaga ccgaacgccc gaccttcaag cccctgcacg gccggtcgat
    10201 ctccaaggcg gaggcgtcgt cggtgatgcg cacgatcggc aaggacgtgc gcgccgccct
    10261 ggagcagccg gaccccctcc ccgacaccac cgatctgtcg gggccctggc cgatcaccgg
    10321 ccaccggttc ctgagccgcc tcgtcctgcg cgacgacccg taccggctgc gcatcctcat
    10381 gtcgcgcacg ctggagatcg acccccggct cacctggacc accatcgtgg ccggggcggc
    10441 cctgccccgg cggcccgccc cggggcccca actgacccac ctggccaacc tgttcgccga
    10501 ggcgggcacc taccacgacc ggcgctacgc catgggcatc taccgccgcg cggccgcgcc
    10561 cgtctgcttc accgtctcca ccctcgtcgc caacgccctg tggctcggcg ccccgttcgc
    10621 cgacgacgcg agcaaccgcg acatcctcta cgaggcgatg cgtctgctgc ccccgtcgtg
    10681 gaacctcctg cgcaaccgat ccgccgaata tccggcgatc gacgaccgca tcgggcacga
    10741 ggacgacatc ctgatgctgc cgttgctcac ccaccgcgac cccgccctgt gggaggcgcc
    10801 gaacgagttc cggcccgagc gctgggaagg gctcgacccg gacaacaccc ccggatatat
    10861 gcccttcgga catgtctcgg agcgctgctg gggtcgccac atggtgatgc ccctggccga
    10921 gctcctcctc gaccacatac gccgtaccgg acttgtggtg gccccgggcc agcgaaccgc
    10981 cgaggtaccc ctggtggggc tgctcggcgt caagaccgtc cacctgggcc atcggagcaa
    11041 ggtccgccat ggctgacgtc gagacccccg acgcgtcgtt cttcgaccac ccgcacgctg
    11101 tctaccgccg gtggcgcgag gagggcggga cgcgccaggt ccggtatccc gggcccgcgc
    11161 cggtcgaggg gtgggtcgtc acctcccacg cggaggcgaa acgcctcctc gccgacccaa
    11221 ggctcgccaa gggcggggcg gtggagaggt tcgggcggca caccgggctc acccggggtc
    11281 ccggcagcgc cctgttcgcg catatgctca actccgaccc gccgcaccac acccggctgc
    11341 gcaaactcgt ccagaaggcg ttcaccgccc gccgcacggc ggccctgcgc cccctgatcg
    11401 aagcccgggt gacgggtctc ctcgacgcct gggaggggcg cgacgaggtc gaactgatca
    11461 gcgagttcgc cctgccgctg ccgatggccg tcatgttcga cctcttcggc gcctccgacg
    11521 ccgaccacga ggtgctgcgg gtgcggggca acaccctcga cggcggccag ggcgacggcg
    11581 aggtgtcggt gttcaccgcc gagtccatgc tcacgtatct gcgggcgctc ctcgccctca
    11641 aacgcgaaca gcccgacgac gggctgctgt ccgcgctggt cgcggcaggc gatgagggtg
    11701 cggaaggcac ggagggcgag gaggcgctca gcgaggacga gatcacgtcg atggctttcc
    11761 tcctggtgat cgccggtcac cagaccaccg tcaacctgat cgccaacggc gtccacgcgc
    11821 tcctcaccca cccggagcaa ctcgcggcgc tccaggccga catgacgctc atgcccggtg
    11881 ccgtcgaaga gatcctgcgc tatgaatccc cctccgccct ggcctcgctg cgctacgccg
    11941 ccgagcctgt cggcgtcggc gaagcgaccg tgcgggaagg cgagttcgtg cagatctcgc
    12001 tcctcggggc caaccgcgat cccggtgtgt tcgccgaacc cgaccggttc gacatccgcc
    12061 gtgcggacgc cgcccggcat ctcgcattcg gccacggcat ccaccactgc ctaggtgcac
    12121 cgctcgcccg tctccaggcc gagatcgcct tcagtcacct gctgacccgc caccccggtc
    12181 tgcgtctgag cgaggaccac gaggcgcggt ggcaggccaa cccccgccac cgcggactgc
    12241 tctcgctacc gctacgactc acctaggacg cgggtgtccc ggcccggtcg gctactgctt
    12301 cgcggcacag atcacgtcgt agggccggcc gatggccatg gtcagacgca tgggctcggt
    12361 cgtccccgac gggcactgcg aagtctgctt cgtcaggtcc agcaccttgt aggcgcccga
    12421 acccgaggag gcgcaggaga cctccttggc cgtggacgtg acacagtcac ccttgaccaa
    12481 ctgaccgcct ccggcgccgg gatcaccggg gtggttggcg gacaggttgc gcccacacac
    12541 cgtcttggac gggatgccgc cgcccttgct cttgctgctg ccgtaactga tgctcacctg
    12601 gatgatgagg tcggtgccgc ccgggcactg gatggagtcc ggcatgaagc tcgcggcctg
    12661 gatgtcgagg gccttgaacg tggcgcccga cgcgccgcag tcgaacgcct tgtagccgtt
    12721 gggcgcgtca tcggggtcgg gccctccgca gtcgcccacc ttccactcgc ccttgtcatg
    12781 ggacgacgac gaggacgagg aggacgacga ggacttcttg ccgtcacttc cgaagaactt
    12841 ggacgccccg aagccgaggc ccaggatgac caggagaatc accagtgcgg ggaggcagcc
    12901 ccctctcctg cggggttggc tgggcacagg cgtactgccc gggtggacca tgtgtgtttc
    12961 cctcctggga acggcggatg acgtgaccac aggggtggac gcggcatgca cacctcatgg
    13021 ttcctcccgg cgcgggcaca cgctcacccc gcccgcgacc ggacccccgc cctggccggc
    13081 tcagccttcc gcggacttgc cccggggttg gcacgtcatg gtcagggggc cggggccgag
    13141 ggtgccgcgg acccgtacgg tcatggtgct gccggggtcg ggcaccaaac gccagcgagc
    13201 gcacaccgtg gcgagcgcga gcgtcatctc gatgagggcg aactggtcgc cgatgcactt
    13261 gcggttgccg ccgccgaagg ggacatgagt accccgcgga agggactcgg cggggcgggt
    13321 gtcccaacgg tcggggtcga agcgttcggg gtcggggaac agctcggggc ggcgctggag
    13381 caggtaggcg ctgtacaaca gggcggtgcc cttggggagt tggcggccgg ccagcgtggt
    13441 gtcggtggtc gtgacgcggg tgaagaacca gcccgccgga tacagacgca ggacctcgtt
    13501 gatgacacgc cgggtgtgga tcaggccgtc gaggtcggcg gtggtggcgg tgcgcccggc
    13561 gagggtcgcg tcgacctcgt cgtgcacccg cgcctcgacg tcggggtgct ggctcagcag
    13621 ccacagggcg aacgccaggc tgttggcggt ggtttcgaac ccggcgccga tcatgaccat
    13681 gagctggtca cggatgtcca catcggacat cggagcgccg gtgtcgtcgt tggtcgcggt
    13741 gagcagcatg gagaccagat cgtcgccgcc cggcgccgcc cggcgtgcgg cgatgatgcc
    13801 gtcgatggcg tggtgcagcc ggtcgcaggc gcggcggtag cggcggttgg cggccgtggg
    13861 cagccggtag agcgggccga ggggcagcat cacccgctgg tagatcccgt cgatcacggt
    13921 gtgcaggctc tgctggacct cggccacggc ctcgtcctgc gcctcggcgc cgagcacgct
    13981 acgggtgacg atgcgcagcg tcagggtggt cagcgcatcg gtcacgtcca ggcgcagacc
    14041 gggccgccac cgcgtggtca tccggtcgac ctcctcgccc atgaccacgg cgtacttctc
    14101 gatccggtcg ctctggaagg cgggctgcat ctgccggcgc tgccaccggt gctcctgcca
    14161 gcccgccatg ggcaggctgc tgccgaagag cacacgggcc ttgtcgaaga aggggccgcc
    14221 cttgtcgaag gtgcgggagt cggtgagcat gcggtgcgcc gcttccggtt cacacaccac
    14281 gtacgcgggc cacgggccca taccgatccg tacgagatcc ccgtaggcgg gcagggagga
    14341 caggaactcc agcgggcggg agtggagttg ccatgcgtgg cccaacaacg gccaggcacc
    14401 gggggctttt cccgtacgcg acggaagctt cgtgctcacg gtggggcacc tccatgcgga
    14461 gtccggcggc cgggcgaccc tcgtagtccc cggatcccga acatcctccc cctcggccac
    14521 ggtggggaac ccggcgcgaa gcagcggaaa acggcgtgcg gtcacgcgcc ccggcgcccc
    14581 acagtgcacc cacgttccat ggggcgggac gccatgtgcc gtacgcatat ggcctgttgg
    14641 gagtggaacc taggagtgtg ggggccccgc gccctgaagg cgttccagat ccgaggggcg
    14701 cacctgaatg gccaggacgg cgatcagcgc ggcgatcacg gcgaagatcg cggccaccac
    14761 gaaggccatg gacacccccg aggtcagcac ctggtcgctc cacggccggg gtagttgacc
    14821 cgtgcgccga aacatcaggc gctgcgccgg gtcggcctgg cccaggaact tggggatctg
    14881 atcccgtgcc tcgttgcggc cggccgtgcc gaacacggtg accaggatgg acaggccaag
    14941 cgaaccgccg acctgctggg tcacgttgag catgccggac gcggcgcccg cctcgtgcgg
    15001 cgggacgccg gagaccgcca tcagcgtcag ggagacgaag ttgagaccca tgcccaggcc
    15061 gaagacgagg agcgggccca ggatgctgcc gggataggtg gagtggatgt ccgtctgggt
    15121 gagccaggac aaaccgccgg cggcgaggat cgcaccggtc accatgaagg gtttgggccc
    15181 gtatttcggc aggagttggg aggtcaggcc cgcacccacg gcgatgatcg cgctgaccgg
    15241 gaggaaggcg agacccgcct ggagggccga gaagccgagg acgtcctgca cgaacagggt
    15301 gaggaagaag aacatgccga agatcgcggc cgagaggctc agcatcatgc cgtaggtgcc
    15361 cgcgcggttg cggtcggcga acatgtgcag cggggtgatc ggctgctgag agcgccgttc
    15421 caccaggacg aaggcggaca ggagcaccac cgcggcggcg aacgacccca gcgtgaacgg
    15481 atcgcgccag ccttcctggg cggcccggat gaagccgtag accagcgcga ccatgccgag
    15541 ggtggaggtc gtggcgcccg cgatgtcgaa atggcccgcg tgccgttcgg actccttgat
    15601 gtgccggggg gtggccagca ggatcagcac ggcgatcggc acgttcacga agagcaccca
    15661 gcgccagtcg agccactcca ccagcacgcc gcccgccagc agaccgatcg cgctgccgcc
    15721 cgccgagacc gcggcgaaga caccgaacgc ccggttgcgc gcggggccct cggtgaacgt
    15781 ggtggtgatc aacgccaggg cggtcggcga ggcgatcgcg ccgccgacac cctgaacggc
    15841 gcgcgccgcg agcaactgcc cggcgttctg cgacagcccg ccgaacaggg aggccagcgc
    15901 gaacagcagc acaccgcaca tgaacacccg gcgccggccg aggatgtcac cggcccggcc
    15961 gccgagcaac agcagcccgc cgaaggtgag ggtgtatgcg ctcaccaccc aggccagact
    16021 cgtggtggag aagtgcaggg cgctctggat gtgggggagc gcgatgttca cgatggtgat
    16081 gtcgaggacc accatcagct gacaggcggc gatgaccagg agcgcgatcc cgttgccacc
    16141 gcccccgcca ctggggggcg cggtctcgac cttcggtgcc ggctgcgaac tggtcatggt
    16201 ggtcctgccc tcaccagagg gacggtggac ggtcacgtcc accgttcgac cctatgcccg
    16261 ggtttcggac gtcaccagtc gatcatgggc cggcccgcaa ggggacgcgc acggacggga
    16321 tcgtgccgac gactgccccc ggggccgggt cggcgcggca tcggggcggg gcaggatcgg
    16381 ggcgtggcgg cggcccactc gggcaaccgt cccgaggggg gcgggcgcgg gacactcagc
    16441 ggtgaccgca cgcgaggagg gcggagtggg gcagggccaa ctccccacgc ccgatggtga
    16501 attcggcact gagcaggtcg aagtggcgcc ggatctcggc gcggatccgc tcgggccgac
    16561 tcgctacgac ctgcccgacc gtgccgaggc ccgcggccgc ccctgcccac cacgtgtcgg
    16621 ctgggacgcg gtgctcccag tggaccggtt cgcaggtgac atcgcgcagg ccggacgagg
    16681 tgagcagccc ggccaggccg ggcacggtgc gggggaagtc gtcctcggcg gcgggcgccg
    16741 acagtccgga tggcagggtt acgcccgcgg cccgcacggc ccggcccagc agggactgcc
    16801 ccgccgcttc gggcacggcc cagagcgtca ccgcgatccg gccgcccgga cgcaccaccc
    16861 gacgcagctc ggcgatcgcg gcgcccggcc ggccgacgtg gtcgaggacg aagttcgccg
    16921 tgacagcgtc gaagaagcca tccgcgaagg ggagttgggg gagtacggcg agctggatgg
    16981 cggcctgggg aaccgcgcgc gccgcccagt caaccatgtc cacctcggcg tccacgcccg
    17041 tcaccccggc gccccgcgcg caggccgcct cggcgaccgt ccccgtaccg gtgcccacgt
    17101 ccagtacccg caccccggcg cccacccggg ccgcgtcgag cagttggggg accgggtggg
    17161 cgcagacccc ggcgaagctg gacgcgtacg cctgcgcccg tcccgcccac atcaaccgct
    17221 ggaccgcgtc gaagtccgtc ggctcccccg gccccggccg gctccgcccc cgccgcttac
    17281 tcgtgaaggg cgccggtgac gcggtcggct cggaaccctc tcccatcgca tgcatcccgg
    17341 caccctacgg gagcgagacg gagcccgggg aaagatgccc gggctccgtc gccgggactc
    17401 acgcccggcg ccagcgggga gcaacaccct tgtgtgccac ggcacttcag gacgcgagcg
    17461 ccggggcgtt ccggccgcgc gggccgagtg atctcaggcc gtgaggacgg agtcgtcgaa
    17521 ggtgcgggcg ccgggcagcc ggtggcgggc ggcgatgacg gcggcatcga tgtccctggt
    17581 gcccgtcgac acgcacaggg tgtacgtcac gtcgtccagc cgctgtcgcg tcgcctcgtc
    17641 accctcggcg gcattcagca cgagcagcgc ctcgtactcg tcgagcagat cgcggagcac
    17701 tgccggatgc gccatcaaca tgggtgggac cctccagtcg acacggtcac gatgttcttg
    17761 atgtgccgct ctggtgcccc gctccacgcg ccccacacgt ggcacatcca agggtggccg
    17821 gatgccgtcc atgagccttc acacccctcg tcccgcgtca ccggtatccg ctaacgccca
    17881 gcaggacgga cctgggcgag ggattcgagt acctcgcggg ccaggcctcg ggccagctcc
    17941 accttgtacg cgttgtggcg cagcgggacc gcgtcggcca gctcggcgtc cacggcccgc
    18001 tcgatcgtct cggcggtcgg ggcggtgccg agcagcgcgg cctccgtccg ccgggcccgc
    18061 cacggccggt gcgccaggcc gccgaaggcg agggcgacct cgcgcaccac cccgcgctcc
    18121 agatgcacca gcgcggcgac cgaggccagc gcgaaggtgt ggcccgcccg gtcccgggcc
    18181 ttgcggtagc gcgagacgga gccttcgggc gcggacggca ccaccacggc cgtgacgatt
    18241 tcgcccggcc gcatcacggt gtccacctcg ggtctgtcct gcggcagccg gtagaactcg
    18301 gtcaccggga cggcgcgggt gccgccgggg ccctccagct cgaccagcgc gtcgagcgcc
    18361 gccagcgcca ccgccaggtc ggacggatgc gtcgccacac agagcgagga gtggccgaag
    18421 acggcgtgct cgcggttcac gccctcgatc gcgccgcacc cgctccccgg cacccgcttg
    18481 ttgcagggcc tcgacaggtc ctggaaatag ccgcaccggg tgcgctggag cagattgccc
    18541 gcggtggtcg ccatgttgcg caactgcccc gaggcaccgc tgagcagcgc ctgcggcagc
    18601 acgggatagc ggtcccgcag ggcaggatgg gtggcgaggt cgctgttgcg cacggtcgcc
    18661 ccgacccgta ccgagccgtc cggctgctcc tcgatcgcgt ccaggggaag ccgggtgatg
    18721 tcgaccagca ggtcgggacg ctcgacgccg agtcgcatca ggtcgacgag gttggtgccg
    18781 ccgcccagat agcgggcctc cggccgtccc ccgtgggcgg cggccgcctc cgccaggttc
    18841 cgcggtcgta cataggcgac tggcttcaca cgatcacatc ctgtacggct tcggcgccgc
    18901 tcgggtaggc cccgcaccgg cacagattcc cgctcaggcg gtcccgtacc tcggcggcgg
    18961 tcagccgcac cggcgcgtcc ggcggcaggt cgatgtcggt gacgacggag gacggcccgg
    19021 aaggggcgcc ggcggacccg gcggcggcag agcggtgctg atcgggggcg cagtacgcgc
    19081 actggaccac atcccggtcc acgacggccc ggcgcaacgg gtgacggtcg tcgtcggcat
    19141 ccgccgccac caggccctcc acggtgacga tctcccgtcc ctcctgggcg acggccagca
    19201 gcagacagct gttgacccgc cgtccgtcga gcagcaccgt gcactcgccg caccgaccgt
    19261 cgtcgcagcc cttcctcgag gcggtcagac ccaagttctc gcggagtacc tccagaaggg
    19321 tggcgcagtg ctccagctcc acccggtgct cggcgtcgtt gacccgcagc gtcacatggg
    19381 agtccgtcac gccgtggccg aagacccggg tgacgagccc cgggcggcgt tcctgtcggc
    19441 cgtgtcttgc ttccaccgtg cacgacctcc tcgatccggg cgggtcagcg gcctgaccgc
    19501 ggtacccacc ctcgtacagc tcacctcctc cggcatctcg gcgcgaggca tccgggacgc
    19561 cggaccgcgc ggcccgggac ggcccacccg ggggatcgcc aacccctcta gcggccgccc
    19621 cgcaccgttg cggcgttacg ggcgcctagc cttcggcggg tgccggcgcg aggtcgtccg
    19681 cgaccaggcc ggccagtacc gcctggccca gggcgtgcac cgcggactgg gggcggacca
    19741 tcacggtgaa ctccttgatc aggcccgcct cgtcgaactg gagcaggtcg atgccgtgga
    19801 tctgcttccc ggccaccgtc gcgcggaacg gcaggaccac cgagggcgcc tcctcgccgt
    19861 cggcgctcgt ctcggcagca ccgtcgagcc ggccgaggta gcgcaggtcc tcgaagacgc
    19921 gcaccaggac cccgaagagg ccgagcacca tggcccggcc ctcgaagggg acgaacttca
    19981 ccgggctgta gagccggacg tcctcggtga acaggccttc cagcgcggac acatcgcgct
    20041 tttccacggc ggcgcggaag cgttcggcag tttccatgac ccctcctcat attcatactc
    20101 aacaaagtga ctactcagat tcttgagtat gatgcagcgg cacgcgagga aaaggaaggg
    20161 ggcttcgatg gctctgcgac acgcggtgct ggcggcgctg ctggacggcg agttcagcgg
    20221 ctaccagctg gccaaggcct tcgacatcgg cgtggcgaac ttctggcacg ccctgcccca
    20281 gcagctctac gccgagctcg ccaaactgga gaaggacggt ctggtcgccg gacgtcaggt
    20341 ggtccaggag acccggccca acaaacgcct cttccacgtc accgacgccg gccgcgccga
    20401 gctggagacg ttcgctgcgg ccacggccaa gccctcgttc atccgggacg acctgctcgt
    20461 caaggtccag gccgccgacc gcatcgggac cgctccggtg atcggccagc tcgaagagcg
    20521 ggcggcggca gccgacgcga agatcgagct actgggcgcg ctgctacggc agttgagggg
    20581 cgatcgggac gaggacgact tcctgctcca cggcgagcgc atcggaccgt atctgacatg
    20641 tctgcgcggt ctggccttcg agcgcgagca ccgggactgg tgccgccgga tcgcggccgt
    20701 cctgcgggag cggcacaggg ccgacgccga gcggtgagga cgggtcccgc cgcaggtcgc
    20761 cgcggggacg gcggtcgcga gcccgagcgg tcggacggat ccggcttggt tacgctgggg
    20821 acgacagcac atggtcgaac ggaacaagga gcagacgtga gcgagccggc gtccatcgcc
    20881 cttcagcagg agatcgcccg ggagctggag gtcgccgaga ccttcgaggc cgagcgggag
    20941 atcgaacgcc gggtggcctt cctcgccgag cggctgacct ccaccggtct gcgctgcctg
    21001 gtcctcggca tcagcggcgg cgtcgactcc acgaccgccg ggcgactgtg ccagct
//
