LOCUS       NZ_CP032698            10228 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces hundungensis strain BH38 chromosome, complete genome.
ACCESSION   NZ_CP032698
VERSION     NZ_CP032698.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces hundungensis
  ORGANISM  Streptomyces hundungensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Relationship between Morphology and Antimicrobial Activity in
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2018) Microbiology and Molecular biology, Chungnam
            National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea,
            Republic of
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: RS HGAP Assembly v. v3.0
            Sequencing Technology             :: PacBio RSII
            Assembly Date                     :: 2018-07-09
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Genome Representation             :: Full
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003627815.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:42:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,472
            CDSs (total)                      :: 7,378
            Genes (coding)                    :: 7,187
            CDSs (with protein)               :: 7,187
            Genes (RNA)                       :: 94
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 191
            CDSs (without protein)            :: 191
            Pseudo Genes (ambiguous residues) :: 0 of 191
            Pseudo Genes (frameshifted)       :: 103 of 191
            Pseudo Genes (incomplete)         :: 121 of 191
            Pseudo Genes (internal stop)      :: 14 of 191
            Pseudo Genes (multiple problems)  :: 42 of 191
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7271919
            Orig. end                         :: 7282147
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032698.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10228
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="30"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10228
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10228
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5228](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5228)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(1829..4105)
                     /locus_tag="DWB77_RS32330"
                     /old_locus_tag="DWB77_06523"
     CDS             complement(1829..4105)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006606566.1"
                     /locus_tag="DWB77_RS32330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06523"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_120725638.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.4e-38, bitscore:
                     128.6, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPRTSTSQLPPPGHGRRRPAEPTGGRRRASRARRTPRTRRAKA
                     VHSPTILQMEALECGAACLAMVLAHHGRHVPLEELRIACGVSRDGSRASNVLKAARSYG
                     LTAKGMQMEPAALAEVQAPAILFWEFNHYVVYDGMGRRLGRRGVHINDPDKGRRFVTSE
                     DFDTSFTGVVLVLEPGPDFRPGGRKPGVLAALPARLRGTTGTMLASLLASLLLVAVGAA
                     LPALSRTYIDLFLMGHQTSLLGVLFAAMGTMVALTVVLTWLQQANLLRGRVISSTLSSA
                     RFFRHLLRLPVTFFAQRSPADLVQRLQSNDAVAETLARDLTAAAVDGVVVLLYAALLWS
                     YDPQLTVIGVGIALLDVVAMRIVVRLRATRTQKLRADSARLTNTAYTGLQLIETLKATG
                     GENGYFRRWAGQHATTLEEQQRLGVPSAWLGVVAPALATLNSALILWIGGLRAVEGHIS
                     IGLLVAFQALVTRFTAPVTRLNGVAGRIQDFAADVARLKDVENFPVDALHSRPEPPAST
                     RRLKGHVSLDDITFGYSPLDKPLLSGFSLTVGPGQQVALVGGSGSGKSTVSRLISGLYA
                     PWEGTIRIDGQRLEDIPRGALAASVSFVDQDVFLFEGTVRDNVALWDPSIPDDAVVAAL
                     KDAALYEVVARRPGGIHGRVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSALDA
                     ETEHLIIDNLRRRGCACVVIAHRLSTVRDSDEIVVLDHGTVVERGRHEELLAARGAYAE
                     LVGEH"
     gene            complement(4102..4908)
                     /locus_tag="DWB77_RS32335"
                     /old_locus_tag="DWB77_06524"
     CDS             complement(4102..4908)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="DWB77_RS32335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06524"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_120725639.1"
                     /transl_table=11
                     /translation="MQFRQQALSKLQSPEELDLPVRFARPQGRLVLLVTVLVMAAASFW
                     AVTGSLSSTIDAPGILTHAQGSYVLQSPVEGQVTGVFAQEGATLAANAPLLKVRTPQGD
                     RIVRAIAAGRLTSLSATIGSVIATGAGVASVERTGGPDDPLVVMLYVPGDSAAGVPVGA
                     PVDLAVQTVPAERYGVLRGTVAAVGRTVQTPRQIAAFLGDNQLAEQFSRDGMPVAVLVR
                     LDRTQATKSGYRWSSGQGPPYAVDSMTPATGTVHLADRRPLDWLLP"
     misc_feature    complement(4924..4942)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.56"
                     /tool="antismash"
     misc_feature    4925..4941
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.32"
                     /tool="antismash"
     gene            complement(5001..5228)
                     /locus_tag="DWB77_RS32340"
                     /old_locus_tag="DWB77_06525"
     CDS             complement(5001..5228)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157700.1"
                     /locus_tag="DWB77_RS32340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06525"
                     /product="type A2 lantipeptide"
                     /protein_id="WP_120725641.1"
                     /sec_met_domain="strepbact (E-value: 1.5e-28, bitscore:
                     97.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNAPQVETLEISDADLDNVSGGLVGTVLGNVTGTADSVLPVSGI
                     VNSVTGLVGSVTGVNTGAVTGLATGLVAGL"
     misc_feature    5290..5303
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    complement(5299..5308)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.67"
                     /tool="antismash"
     misc_feature    complement(5538..5556)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.26"
                     /tool="antismash"
     misc_feature    5661..5676
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.49"
                     /tool="antismash"
     gene            complement(5672..6724)
                     /locus_tag="DWB77_RS32345"
                     /old_locus_tag="DWB77_06526"
     CDS             complement(5672..6724)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015660526.1"
                     /locus_tag="DWB77_RS32345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06526"
                     /product="chitinase"
                     /protein_id="WP_120725643.1"
                     /transl_table=11
                     /translation="MIGRTLRLLGAGLVLALATQVPVSAAPSAPGADTCAVKSRPSGKV
                     LQGYWENWDGASNGVHPPLGWIPITDSRIGAHGYNVLNAAFPVIRSDGTALWEEGMDST
                     VKVPTPAEMCQAKASGQTLLLSIGGAAAGIDLSSSAVADRFVASIVPILQRYNFDGIDI
                     DIETGLVGSGSLTTLSTSQANLIRIIDGVLARMPSTFGLTMAPETAYVTGGSVTYGSIW
                     GAYLPIVKKYADNGRLWWLNMQYYNGSMYGCSGDSYEAGTVAGFTAQTTCLNKGLVVQG
                     ATIKVPYDKQVPGLPAQPGAGGGYMTTNQVSQAWNAYGGALKGLMTWSLNWDGSKNWTF
                     GNNVRALQGR"
     misc_feature    complement(6707..6709)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(6827..6842)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 21.25"
                     /tool="antismash"
     gene            complement(6947..7423)
                     /locus_tag="DWB77_RS32350"
                     /old_locus_tag="DWB77_06527"
     CDS             complement(6947..7423)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069408.1"
                     /locus_tag="DWB77_RS32350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06527"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_120725645.1"
                     /transl_table=11
                     /translation="MTVDSLDTEILRLLIEQPRTSVREYARILGIARGTLQARLDRMER
                     DGVITGTGPVLSPAALGHPVLAFVHIEVTQGHLNEVGDALAAVPEIIEAFSITGGGDLL
                     TRVAARDNEHLEDVIQRLIQLPGVVRTRTEVALRERVAHRLLPLVESVGRASAK"
     gene            7508..8020
                     /locus_tag="DWB77_RS32355"
                     /old_locus_tag="DWB77_06528"
     CDS             7508..8020
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058069.1"
                     /locus_tag="DWB77_RS32355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06528"
                     /product="DinB family protein"
                     /protein_id="WP_120725647.1"
                     /transl_table=11
                     /translation="MKTGEFVADAFGRVQELVHAAVKGLSAEELAFRPDDEANSIAWLI
                     WHLTRVQDDHIADAAGGDQVWTAQGWAERFGLSLADEETGYGHTTEQVAAVRDVSAEQL
                     RDYYDAVHEQTLSFVRGLDEVALDRVVDERWTPHVTLGVRLTSIIADDLQHAGQAAYVR
                     GLLKRRR"
     gene            8223..9743
                     /locus_tag="DWB77_RS32360"
                     /old_locus_tag="DWB77_06529"
     CDS             8223..9743
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601805.1"
                     /locus_tag="DWB77_RS32360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06529"
                     /product="FUSC family protein"
                     /protein_id="WP_120725649.1"
                     /transl_table=11
                     /translation="MVKRVFVAPDPGRLRLRAAMRAVLGIGLAVVACGAVGHSLVAAIT
                     GGLAALLALFTVTDPSVRSQAVTTALLPVVGLPVFALAAVLHGHPWARDLAFLAIVGGG
                     VFARRWGPRGHALGVFAFMAFFVAQFLHMVPSQLPELYVAVLLSLAMAAAVRFGAWCYE
                     RRHSAPVVMTAPAPGRGLYRATTRQAVQAVVGAGFALAVGQLLSPDRWYWAVGATWWIF
                     VNTTSRGETLVRGFRRVLGTVIGVGIGLAVAVPLHGAPVPTAVLIALCVFGIFYTAAVS
                     YTWMMLAVTVMASLLYGLLGVLNTDLLALRFFETGVGMTGSVLAVLLVLPITTHATTDA
                     WVRHALHSVRASAATAAARLAGADADPLPHIAELEFTLNKVRLSLAPLVHPLNPLRARK
                     ARARQVLAYLDDCARQAHQLAAIAADAEASHDQRLTAACERVEAAVAVLVSSPSTADSA
                     ARAVAPEHKDATAAAEHPALAHLHALERALVGLGRPLQAAPGSPLADA"
ORIGIN
        1 ggctgcgggc gaactcgccc gcccacgccc cgtacgcgaa gctctccgcc gcggccaccc
       61 gcagcttggg caggccgcgc agggtctgga acgcctggtt gttcagcttg ttgcccagtt
      121 cgaccaggcg gcgctgccag cgcagctctg ccatgccgag ggtcaggaac acggcggcga
      181 tgacgatcaa cagggccacc gtcaccagcg ccaggggcac gctgaagcac agcaggagga
      241 cgaggttcat cacggcgacc gtgcccgcct gcacgacgac cggtccgatg cccgtcagga
      301 cccgccggat cgcgctcacg cccatcgccg cactggccag ttcaccggtg gagcgctcgg
      361 cgaagaaccg ggtcggcagc ctcaaaagcc ggtcccatac ggcgggttga agggtgctct
      421 cgatgcgtcc ttccatccgc agcacggtga ggttctggag cagcgcgaac gcggcggaca
      481 cgatgccgct caccaccacg gccagcgaga cctgcacgat gaggctgctc tgggcgcgcg
      541 gaacgtacac gccgaggacc tgtccggtgg cgatcggcac cagcgcgccc agcgccaccg
      601 tcaccagggc cgcgagcagc agccggtgta tgtcggcgcg ggtgccgcgc aggctgaacc
      661 ggagcagccc ccgcttgccc agtggccggt cgggcagcgg ccggtagaac atgacggcgc
      721 gcccctcgaa ctcctcggcg ttgtcggcgt cgacacgggt gcggcgaccg gagagtggat
      781 gcaccgcctc gtacccgccg cgccgccaca gcagggcgac gggggtgccg ctcacccgcc
      841 gcccgaccag cggccccgcg tcctcgcgcc accagcgccc ggccagccga acgggccgcg
      901 tccggatgcg ggaggccacc gcgacccgct ccaccggatc gacgcggtcg ccgatcgccc
      961 cgccgagcgc ccggtcggcg agggtgatcc cggccgcgtc cgcgaccagc cgacaggccg
     1021 cgtacgtcgc gtcgtcggtg gggcccgggg tgcgcgcggg cgccttgcgg gtgcggccga
     1081 tggaggtgag cagcgcccgg tcggcctcct cgcggacggc ctcacccgct ctgatcccgg
     1141 ccgccgtacg gttttcatgg gcccgctcca cgcgttcgat ccagcggtcg agggccgaga
     1201 gcagccggta ctgctggttg accatgccct gccacagcgc cccgtcgacg agcaggtcgc
     1261 cggcggcctc ggcgctgaac gccgcgccgt actgcacact gcccggcgac accggaagcc
     1321 acaggatgtc gtcgtccgcc accgactcgt cgagtgcggt ccggccgtcc aacggggcct
     1381 cgaacaggac cctttggccg cgcccgatgc ccagcgagaa ggcgtgctcc agcaggctga
     1441 gggtcgcgtc cccggcgtcg taccggctcg ggtgcgcggc tgcgtacccg tcatacggtt
     1501 cgcggtacag ctcgcgcagg ggaatgcggc gcagtacgca ctcccgcagg ggccgcccga
     1561 ccagcgtgtg ccgtgggccc tcgacggggc cgagcagcag ggtgcccggc tccagccggc
     1621 ccaggaagtg ccagtgcccc tgctccgccg cgtccaccgc gaacagatcc agggctccgc
     1681 ccaccacgag ccacagcacc tggggcccct ccagggagaa gccgccggaa ccggtgcggt
     1741 cgacgggctg cccgagtccg ccgagcgcgc cgacgacggc gtcccgcccc gaggcgtcct
     1801 gggcggccgc agcgtgtacg aacgtcactc agtgctcccc gaccagctcg gcgtaggccc
     1861 cccgggcggc caggagctcc tcgtggcggc cgcgctccac gacggtcccg tggtcgagga
     1921 ccacgatctc gtcgctgtcg cggacggtgc tcagccggtg ggcgatgacg acgcacgcgc
     1981 agccgcgacg gcgcagattg tcgatgatga ggtgctcggt ctcggcgtcc agggcgctgg
     2041 tgacctcgtc aagcaccagg atgctgggcc ggcgcaccag cgcccgggcg atctccagac
     2101 gctggcgctg accgccggag aagttgcgcc cgtcctgctc gacccggccg tggatgccgc
     2161 ccggccggcg cgcgacgacc tcgtacaggg ccgcgtcctt gagggcggcc accaccgcgt
     2221 cgtccgggat cgaggggtcc cacagcgcga cgttgtcccg caccgtgccc tcgaagagga
     2281 agacgtcctg gtcgacgaag gacacggacg cggcgagggc gccgcgcggg atgtcctcca
     2341 ggcgctgccc gtcgatgcgg atggtgccct cccagggcgc gtacagaccc gagatgagcc
     2401 gggacaccgt cgacttgccg ctccccgaac cgcccaccag agccacctgt tggcccggcc
     2461 cgaccgtgag cgagaacccc gacaggagcg gcttgtcgag cgggctgtag ccgaaggtga
     2521 tgtcgtcgag gctcacatgg cccttgaggc gtcgggtgct cgcgggcggc tcggggcggc
     2581 tgtgcagggc gtccacgggg aagttctcga cgtccttgag gcgggccaca tcggccgcga
     2641 agtcctggat ccggcccgcg acgccgttca gccgggtcac cggggccgtg aagcgggtca
     2701 ccagggcctg gaaggcgacg agcagaccga tggagatgtg cccctccacc gctcgcagcc
     2761 cgccgatcca caggatgagc gcgctgttga gggtggcgag cgcgggggcg accacaccga
     2821 gccaggcact gggcaccccg agccgctgct gctcctccag cgtggtggcg tgctgccccg
     2881 cccagcggcg gaagtacccg ttctcaccgc cggtggcctt cagggtctcg atcaactgga
     2941 gccccgtgta cgcggtgttg gtgagccgtg cgctgtcggc gcgcaacttc tgcgtacggg
     3001 tcgcccgcag ccggaccacg atccgcatcg ccaccacgtc cagcagggcg atgcccaccc
     3061 cgatgacggt gagctgggga tcgtagctcc acagcagggc ggcgtagagc agcacgacga
     3121 caccgtccac ggccgccgcc gtcaggtcgc gggccagcgt ctcggccacc gcgtcgttgg
     3181 actggagccg ctggacgagg tcggcggggc tgcgctgcgc gaagaacgtc accggcagcc
     3241 ggagcagatg ccggaagaag cgggcgctgc tcagcgtgga ggagatgacg cgaccgcgca
     3301 gcaggttcgc ctgttggagc caggtcaaca cgacggtgag cgccaccatg gtgcccatcg
     3361 ccgcgaacag cacgcccagc aacgaggttt gatgacccat caggaacagg tcgatgtagg
     3421 tgcggctcag tgcgggcagc gcggcgccga cggcgacgag cagcaggctc gcgagcagcg
     3481 aggccagcat cgtgcccgtg gtgccgcgca gtcgtgcggg cagcgcggcc agcacaccgg
     3541 gcttgcggcc gccgggccgg aagtcggggc cgggttccag gaccaggacg acgcccgtga
     3601 agctggtgtc gaagtcctcc gacgttacga accggcgccc cttgtccggg tcgttgatgt
     3661 gtacgccccg ccggccgagg cggcgcccca tgccgtcgta caccacgtag tggttgaact
     3721 cccagaacag gatggcgggc gcctggacct cggcgagcgc ggccggttcc atctgcatgc
     3781 ccttggccgt gagcccgtaa ctgcgcgccg ccttcaggac gttgctcgct cgtgagccgt
     3841 cccgcgagac gccgcacgcg atgcgcagct cctccagcgg gacatggcgg ccgtggtggg
     3901 cgaggaccat ggcgaggcag gcggcgccgc actccagggc ctccatctgg aggatggtgg
     3961 ggctgtgcac ggccttggcc cgccgggtcc tcggcgtccg gcgggcccgt gacgcccggc
     4021 gcctgccgcc ggtcggctcg gccggtcggc ggcggccgtg gccggggggc gggagctggg
     4081 aggtggaggt gcgcggtgcg gtcacgggag cagccaatcg agggggcgcc ggtcggccag
     4141 gtggacggtg ccggtggccg gggtcatgga gtcgaccgcg tagggcgggc cttgtcccga
     4201 cgaccagcgg tagccggact tcgtggcctg cgtgcggtcg aggcgcacca gcaccgccac
     4261 cggcatgccg tcccgcgaga actgttcggc gagctggttg tcgccgagga acgcggcgat
     4321 ctggcgaggc gtctgcaccg tccggccgac cgcggccacc gtgccgcgca gcaccccgta
     4381 ccgctcggcc ggcacggtct gcacggcgag gtcgacgggc gcgcccacgg ggacaccggc
     4441 ggcgctgtcg cccggcacgt acaacatcac caccaggggg tcgtcggggc cgcccgtgcg
     4501 ctccacgctc gccacgcccg cgccggtggc gatgaccgag ccgatggtgg cggagagact
     4561 ggtgagacgg ccggcggcga tcgcgcgcac gatccggtcg ccctgggggg tgcgcacctt
     4621 gaggagcggc gcgttggccg ccagggtcgc gccctcctgg gcgaacaccc cggtgacctg
     4681 tccctcgacg ggactctgga ggacgtaact gccctgtgcg tgcgtgagga tgccgggtgc
     4741 gtcgatcgtg gaggaaaggg agcccgtcac ggcccagaaa gaagcggcgg ccatgaccag
     4801 aacggtgacg agaaggacga gtcgtccctg cgggcgcgcg aaacgcacgg gcaggtcgag
     4861 ttcttccggc gactggagtt tggaaagggc ctgctgacga aactgcacgg aactctttcc
     4921 ctatccgcga aacattcgca aaccgttggc catcggcaat gagccccgga accgagtggt
     4981 tccggggctc gcgcgcgatc tcagagaccg gcgacgagac cggtggccag gcccgtgacg
     5041 gcgcccgtgt tcacaccggt gaccgagccg accaggccgg tgaccgagtt gacgatgccc
     5101 gagaccggca ggacggagtc ggcggtgccg gtcacgttgc cgagcacggt gcccacgagg
     5161 ccgccggaca cgttgtccag gtcggcgtcg gagatctcga gggtctcgac ctggggagcg
     5221 ttgttcatgg gagtactgcc tttcatgggg acatttccta tcgggaacac cttgccggtg
     5281 ctcccgcagt gggcaggatc aaaacacgcc gacggcattc acagccaatc gccgccgggt
     5341 gtcgtgggca ttccccaccg cttgaattgc cgtcccgtgc aggcgcgttc ataagttggg
     5401 ggcagtttct tcacgagctt cacgagttgc attcctgagg gtccgtcagc gcattactca
     5461 agtgggacac tcccgcacca atgcccctcg ggccgccctc gtgcccgggc gcgttcatgg
     5521 tcgcggtgac gggtccgcgc acacggtgtg cagattctcg gaaggaaccc ttccgcttgt
     5581 ctcgggggca cggagcgggc ccgggccgga cgcgaaccgg acccggaccc ggcggggagc
     5641 ccaggcccgc gcccggtgcg gatgacacgc gtcaacggcc ttgtagcgcc ctgacgttgt
     5701 tgccgaacgt ccagttcttc gagccgtccc agttgaggga ccaggtcatc aggcccttga
     5761 gggcgccgcc ataggcgttc cacgcctggg acacctgatt ggtggtcata tagccgcccc
     5821 ccgcgcccgg ctgggccggg agcccgggga cctgcttgtc gtaagggacc ttgatcgtgg
     5881 cgccctggac gacgagcccc ttgttgagac aggtggtctg cgcggtgaat ccggcgacgg
     5941 tgccggcctc gtaggagtcg ccggagcagc cgtacatgct gccgttgtag tactgcatgt
     6001 tgagccacca cagacggccg ttgtccgcgt acttcttcac gatcggcagg tacgcgcccc
     6061 agatcgagcc gtacgtgacg ctgccgccgg tgacataggc ggtctcgggc gccatcgtca
     6121 gaccgaaggt ggacggcatc ctggcgagca cgccgtcgat gatgcggatc agattggcct
     6181 gggaggtcga gagggtggtg agggagccgc tgcccaccaa gcccgtctcg atgtcgatgt
     6241 cgatgccgtc gaagttgtac cgctggagga tcggcacgat cgacgccacg aagcggtcgg
     6301 ccaccgcgct cgaactgagg tcgatgccgg cggcggcccc gccgatcgac aggagcaggg
     6361 tctggcccga cgccttggcc tggcacatct cggctggggt cggcaccttc accgtcgaat
     6421 ccatcccctc ctcccacagg gccgtgccgt ccgaacggat cacggggaag gccgcgttga
     6481 ggacgttgta gccgtgggcg ccgatgcggg aatcggtgat cgggatccaa ccgagcggcg
     6541 gatgcacgcc gttggacgcc ccgtcccagt tctcccagta cccctggagc accttgcccg
     6601 agggtctcga cttcaccgcg caggtgtcgg ccccgggcgc gctcggcgcc gcgctcaccg
     6661 ggacctgcgt cgcgagcgcg agcacgagcc cggctcccag cagacgtaac gtacgaccga
     6721 tcatgctgtg ctcctagcct ccgggagcgc ccatggcggg gcacggccgc tcctggaccg
     6781 tggggggacc tgaggaggtg cgagggggtg gcgccccaca ccgtagattg gtccagacct
     6841 tccgtcaatc gggtcgacgg gtcggtcctc ggcctgacgg gtcttcagga gccgtgcgtg
     6901 gaaagggaat tgggcgtggg acggccgtgg ccgtccccgg tgtcgcctac ttcgcggagg
     6961 cccgccccac cgactccacc agcggaagca gccggtgcgc gacgcgttcg cgcaacgcca
     7021 cctcggtccg ggtgcggacc acgcccggaa gctggatgag ccgctggatg acgtcttcga
     7081 ggtgctcgtt gtcgcgcgcg gcgacccggg tcagcagatc acccccgccg gtgatcgaga
     7141 acgcctcgat gatctcgggc accgccgcca gcgcgtcgcc gacctcgttc agatgcccct
     7201 gggtcacctc gatgtgcacg aaggcgagca ccgggtggcc gagggccgcg ggggagagca
     7261 ccggaccggt gccggtgatc acgccgtccc gctccatgcg gtcgagccgg gcctggagcg
     7321 tgccgcgcgc gatgccgagg atgcgcgcgt actcgcggac gctggtgcgt ggctgctcga
     7381 tgagcaggcg caggatctcg gtgtcgagcg agtccaccgt cacgttccgt tggctccttc
     7441 tgatcccgcc gatacggagt cgacagtacc aatggcgtcg cgaagatcga tgagtgagga
     7501 tggccggatg aaaaccggag agtttgtggc ggacgcgttc gggcgcgtcc aggagctcgt
     7561 gcacgccgcc gtcaagggcc tgtcggccga ggaactcgcc ttccggccgg acgacgaggc
     7621 caactcgatc gcctggctga tctggcatct gacgcgcgtt caggacgacc acatcgccga
     7681 cgccgcgggc ggggaccagg tgtggaccgc ccagggctgg gccgaacggt tcggcctgtc
     7741 gctcgctgac gaggagaccg gctacgggca cacgaccgag caggtggccg cggtgcggga
     7801 cgtgtccgcc gagcagctgc gcgactacta cgacgccgtc cacgagcaga ccctgtcgtt
     7861 cgtgcggggt ctcgacgagg tggcgctcga ccgggtcgtc gacgagcgct ggaccccgca
     7921 cgtcaccctg ggcgtccgtc tgaccagcat catcgcggac gatcttcagc acgccggcca
     7981 ggccgcgtat gtacggggcc tgctgaagcg ccgccgttag acggaagggg cggcgccgcg
     8041 gccgacactg ggccgatggg ggcgccctgg acatgagaag accgacacaa ctgaaccatt
     8101 ggcacagtcg cacgaggtgg agttgagcca ttgggcgcaa ggatggtgtc ataggggagt
     8161 cgatggcgct gtggtctccg cagcgccttt ctcatgtccg gaggagaaag agagcggtgt
     8221 cagtggtgaa gagggtgttc gtggcccccg acccgggacg gctgcggctg cgcgccgcga
     8281 tgcgagccgt gctggggatc gggctcgcgg tcgtggcgtg cggcgcggtc ggtcactcgc
     8341 tcgtggcggc catcaccggc ggtctcgccg ccctgctggc cctcttcacc gtgacggacc
     8401 ccagcgtgcg gagccaggcg gtgaccacgg ccctgctgcc ggtggtcggc ctgccggtgt
     8461 tcgccctcgc ggccgtgctc cacggccacc cgtgggcgcg cgacctggcc ttcctcgcca
     8521 tcgtcggagg gggtgttttc gcgcgccgct ggggaccgcg cggccatgcg ctcggcgtgt
     8581 tcgccttcat ggcgttcttc gtcgcgcagt tcctgcacat ggtgccgagc cagctgcccg
     8641 agctgtacgt ggccgtgctg ctgtccctgg cgatggccgc ggcggtgcgc ttcggcgcct
     8701 ggtgctacga gcgccgccac tcggcgcccg tcgtcatgac ggcgcccgca ccgggccggg
     8761 gcctctaccg ggcgaccacg cgccaggccg tgcaggccgt ggtcggagcg ggcttcgcgc
     8821 tggccgtcgg ccagcttctg tcaccggacc gctggtactg ggcggtgggc gcgacctggt
     8881 ggatcttcgt gaacacgacg tcgcggggcg agaccctggt gcgcggcttc cgccgggtgc
     8941 tcggcaccgt catcggcgtc ggcatcggcc tggcggtggc cgtgccgctg cacggggcac
     9001 ctgtgccgac cgccgtgctg atcgcgctct gcgtcttcgg catcttctac acggcggccg
     9061 tctcctacac ctggatgatg ctcgcggtca ccgtcatggc gagcctgctc tacgggctcc
     9121 tcggcgtgct caacaccgac ctgctcgcgc tgcgcttctt cgagacgggt gtcggcatga
     9181 cgggatccgt tctcgccgtg ctgctcgtcc tgccgatcac cacccacgcc acgacggacg
     9241 cctgggtgcg gcacgcgctg cacagcgtcc gggcctccgc cgcgacggcg gcggcccgtc
     9301 tcgccggcgc ggacgccgac ccgctgccgc acatcgccga gctggagttc accctgaaca
     9361 aggtccggct ctcgctggcg ccgctggtgc atccgctcaa tccgctgcgg gcgcgcaagg
     9421 cccgggcccg ccaggtcctg gcgtacctcg acgactgcgc ccggcaggcg caccagctgg
     9481 cggccatcgc cgccgacgcc gaggcctccc acgaccagcg gctgaccgcc gcgtgcgagc
     9541 gcgtggaagc cgccgtcgcg gtcctggtct cctccccgtc gacggccgac tcggcggccc
     9601 gtgcggtggc accggaacac aaggacgcca ccgccgccgc ggagcacccg gccctcgccc
     9661 atctgcacgc cctggagcgc gcgttggtgg gcctgggccg gccgctccag gccgcccccg
     9721 gatcgccgct cgccgacgcc tgaccgtcgc cgccccccag ccatccggac cccaactccc
     9781 ctcaccgcac cgccacttgg ggccccggcg cgcccgcccg gatccagcgg ccgagggggg
     9841 ccctgacacc ccctgctacg gtcgccgcag cacagctgtg tgcgggcggg ttccgggtcg
     9901 cggggccggc atcggcgaga ggggtggcac ggtgggcacg gacagggccg ggcgggcgtt
     9961 catcgggtcg ttcaccacgg cgggcgggcg cggggtgacc gcggtcgccg tcgacgagga
    10021 gaccggggcc ctgaccccgc tcggctcgtc ggaccatgtc gcgaacccct cgttcctggt
    10081 cgcctcgccc gacggagccg tcctgtacgc cgtgggggag aacgcccacg gcaccgccgc
    10141 cgccttcgac atcagggacg acctgccccg cccgctcggc gagcccgtgc cggtgggggg
    10201 atccggcccc acccatctcg acctcgcc
//
