LOCUS       NZ_CP032698            20954 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces hundungensis strain BH38 chromosome, complete genome.
ACCESSION   NZ_CP032698
VERSION     NZ_CP032698.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces hundungensis
  ORGANISM  Streptomyces hundungensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Relationship between Morphology and Antimicrobial Activity in
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2018) Microbiology and Molecular biology, Chungnam
            National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea,
            Republic of
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: RS HGAP Assembly v. v3.0
            Sequencing Technology             :: PacBio RSII
            Assembly Date                     :: 2018-07-09
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Genome Representation             :: Full
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003627815.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:42:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,472
            CDSs (total)                      :: 7,378
            Genes (coding)                    :: 7,187
            CDSs (with protein)               :: 7,187
            Genes (RNA)                       :: 94
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 191
            CDSs (without protein)            :: 191
            Pseudo Genes (ambiguous residues) :: 0 of 191
            Pseudo Genes (frameshifted)       :: 103 of 191
            Pseudo Genes (incomplete)         :: 121 of 191
            Pseudo Genes (internal stop)      :: 14 of 191
            Pseudo Genes (multiple problems)  :: 42 of 191
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7172979
            Orig. end                         :: 7193933
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032698.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20954
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20954
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20954
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10954](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10954)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            277..468
                     /locus_tag="DWB77_RS31900"
                     /old_locus_tag="DWB77_06436"
     CDS             277..468
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS31900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_06436"
                     /product="hypothetical protein"
                     /protein_id="WP_120725477.1"
                     /transl_table=11
                     /translation="MEALVSAAVRPGPATHRSADRGPSLARRAAAQNAGKAPANLTRAM
                     AACGDPHVPAASAFQSAL"
     gene            489..2915
                     /locus_tag="DWB77_RS31905"
                     /old_locus_tag="DWB77_06437"
     CDS             489..2915
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SAM_SPASM_FxsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119571.1"
                     /locus_tag="DWB77_RS31905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06437"
                     /product="FxsB family cyclophane-forming radical SAM/SPASM
                     peptide maturase"
                     /protein_id="WP_120725479.1"
                     /sec_met_domain="PTHR43273 (E-value: 6.7e-69, bitscore:
                     231.4, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="SAM_SPASM_FxsB (E-value: 4.6e-175,
                     bitscore: 580.6, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.2e-14, bitscore: 53.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRAIVPALSQFVLKVHSRCDLACDHCYVYEHADTSWRGRPRAVS
                     PEILAQVANRIAEHARRHRLPTVHVVLHGGEPLLAGPDRLRTAADELRRALHGVSALDL
                     RMHTNGVLLDEEFCELFLELGIKVGVSLDGDKVSNDRHRRYADGRSSHAKVIRAIELLN
                     RPRYRPLFAGLLCTTDVENDPVAVYDALLELTPPRIDFLLPHATWDTPPPRPGGAPTPY
                     ADWLDAIYRRWDAAGRPVPVRIFDSVLRTLRGESSLTESLGLAPADLVVIETDGTFEQA
                     DSLKTSYDGAPATGMDVFRHSLDDVLQHPGMLARQQGAEQLCAQCRACPVVESCGGGLY
                     AHRYRTGNAFDNPSVFCPDLLALVTTIRDREAAVPAPTPQSAQLPLDERDFEELAAGFG
                     GADTVGRLAAAQLDLNQELLAAVSAQRIALSDREAAEAWEVLTDLDAEVPDELAGVLAH
                     PYTRPWALDVLGGRAAPAGGLAEIAATTALRARLERTVTVPLRDTTLRLPGFGTVRLDV
                     AATHAEVTAGADGFTVRAGGRRLDIGWHEGVDGLTPHWRPVRLFQGEGWNVAIEDTDPL
                     RDCHEWPVAERLPVGEAKLWSEDLTGAWSLIRRELPAYADGVAAGLRLITPLHAPDGSD
                     VSAACKDAWGAIGVARPASPEQLALLIVHEFQHVKLAAVLDAVDLYDKADRGRYYAPWR
                     EDPRPIGGLLQGTYAHIAVTDFWRVRRETAPLAAERGAAEAEFARWRQQTARAVEVLLG
                     SGSLTDLGERFVGRMGETVADWRDEPVSPAAFSAAEESARRHRVAWEARAEGRTA"
     misc_feature    2916..2930
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.08"
                     /tool="antismash"
     gene            3105..4451
                     /locus_tag="DWB77_RS31910"
                     /old_locus_tag="DWB77_06438"
     CDS             3105..4451
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326098.1"
                     /locus_tag="DWB77_RS31910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06438"
                     /product="TIR-like protein FxsC"
                     /protein_id="WP_246033698.1"
                     /transl_table=11
                     /translation="MQGSVGAGGDEQHPYFFLSYAHTPKSDPKDKDPNLWVQRFFRDLC
                     AHVMQLTPLPAGSAGFMDVQMQPGEGWQERLSEALAFCKVFVPLYSPRYFLSEQCGREW
                     FAFSSRAAAQNTRNSSNNSNPVTGIVPALWVPVPTRQLPQPAERLQFNHATFGDEYADE
                     GFYGLIKLNYLRDQYERAVYRLAKRIVNVAQQTQLEPGDPHQDYAKVPPAFGPAGGPAR
                     EMEVAVLACSRSSLPTGRSPDCYGTEALDWNPYHPTSSRPLADHTVDVVRNLNYTVHLS
                     DFEAEPHRLLASGPPGPGLLLLDRWALDARRRRELLDQLGASRRPWISVMVPGNVADPQ
                     SRARDEELSSQTDAALSTRVNESDGHRTPSGGLPTLEAFSKAIPGAVKAAVRHYEAHAP
                     TYPPPGSGGRMPRVLPGGIGYGAPGPTGRGRSTDQEKNHGDKAEGSSDD"
     gene            4444..8418
                     /gene="fxsT"
                     /locus_tag="DWB77_RS31915"
                     /old_locus_tag="DWB77_06439"
     CDS             4444..8418
                     /codon_start=1
                     /gene="fxsT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119569.1"
                     /locus_tag="DWB77_RS31915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06439"
                     /product="FxSxx-COOH system tetratricopeptide repeat
                     protein"
                     /protein_id="WP_120725482.1"
                     /transl_table=11
                     /translation="MTENRNGTVVTFYSYKGGTGRTMALANCAWILAANGYRVLAVDWD
                     LEAPGLHRFFHPFLDLADLEATPGLINLITDYQDEARRPADRDPDWHRDYARVRPHATS
                     LNWNFPQGGSLDFLSAGRRNRDYPSIVGKMDWDDFHERFGGGQFFDAMRDDMQRHYDYT
                     LIDSRTGLSDIADICTVQMPEVLVVCFTLSDQSIDGASAVARDIEERYHERRIRILPVP
                     MRIDDGEKEKADAGRALARESFPGFPSGLSPEELGNYWGTVEVPYRPFYAYEEILATFG
                     DAPNVSSSMLSACERLTSVLTGGLVNSLPPIDEADRLTHVAAYTRRRPMPPSNLVLTHV
                     AEDQMWADWLVYVLTAAGFHVVPVDVRAPRSSATEAEFTSGAGYRVIPVVSQAYLNSER
                     ARSSWESGTGLDISGGRRHILPVRVGDVRLGPPLSSRGVIDLVRLDEADAGAAVLNALD
                     RSEAVAALASGPPGPRYPGSVPKVWNVRPRHAWFTGRTSVLERLRDQLRGDSRSAQRFP
                     QVLYGLGGVGKTQVAREYAHRFRADYDLVWWIEAEQPDRVVSSLAELAAEMDLRAGDVV
                     AEAATAALQALRRGAPYSRWLLIFDNVEDLDRALKLLPEDIEPIPGETYGHILATCRNK
                     PASTKVEAIEVEVFTRAESIEHLCRRVTKLPTADADRVADAVGDLPLAVEVAAAWLAET
                     ATPVDAYVEQLREQSTKVLSLGKPEDYSEQIGATWNISISRLRDESKAAVRLLELCSFF
                     SAEPISMRLIGSDSMFESLLPYDPDLRERYMLGKVIQTLNRFALAKVDPADSSIQVHRL
                     VQAAVRAGLSDDEVDTAKHEVHRILAEARPVEGVDRDNPVNDPKSWPSFELIWPHLSAS
                     GIADCDEEKVRQLMVDRIRYLLKRGELESARVLGTQLNKVWTRELGENDLQTLNIRFEL
                     ANALRAQGKYQEARAMDEDTLARQISVLRKDHPGDDHPSILITTGSLAADLRALGRFDE
                     ALTRDLTIYHGLRQIFGENHPRTLIAANNLAIDYRLSGDSEAARRLDEETVERRSALLG
                     EDHPFTLTTKGHLGRDLRESGEYAASVQVLREVVSAFERVLNADVPEALRTAKSLAVSL
                     RKAGHPHEAKRLTEETYNRYRGRYGTKAPDALACCLNLAADFSATGDKQAAYDLSLQAL
                     EGYQGTLGEEHPFTLACRNNVYIYQRGLGAAEEAARGGEDVRAALEEVLGSRHPFTLSA
                     AINLANAYGDMGRPDLAERWERTALKGLLERFGPTHPDVLACRSNLAITLRAAGREDEA
                     QRLRTSILEPAAKQLGVDHPIAEAARAWRRINRDLEPQPV"
     gene            complement(8521..9384)
                     /locus_tag="DWB77_RS31920"
                     /old_locus_tag="DWB77_06440"
     CDS             complement(8521..9384)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (24-273). E-value:
                     6.6e-22. Score: 70.2. Matches aSDomain:
                     nrpspksdomains_DWB77_RS31920_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884104.1"
                     /locus_tag="DWB77_RS31920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06440"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_120725484.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-18, bitscore: 66.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.3e-10, bitscore:
                     39.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGELIRTRDGRDLAVENYGNPKGRPVFLLHGTPGSRLGPAPRSAV
                     LYRLGVRLITFDRPGYGDSDRLPGRRVAHAAADVEAIADALDIDEFAVVGRSGGAPHAL
                     ACAALLPDRTARAAALVGLAPRDAQGLDWFDGMTEANVREYINAAAGQGQLTTALEMRS
                     ITIRSDPRRSVADMRHDLPKPDRGIVADAGIRAMLERNFEEALRSSADGWVDDVMAFST
                     DWEFRPEDITAPVLLWHGEQDVFAPVQHTRWLAERIPGAQLIVERGAAHFGALRVLTRV
                     LSWATW"
     aSDomain        complement(8566..9312)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DWB77_RS31920_Abhydrolase_1.1"
                     /evalue="6.60E-22"
                     /label="DWB77_RS31920_Abhydrolase_1.1"
                     /locus_tag="DWB77_RS31920"
                     /protein_end="273"
                     /protein_start="24"
                     /score="70.2"
                     /tool="antismash"
                     /translation="PVFLLHGTPGSRLGPAPRSAVLYRLGVRLITFDRPGYGDSDRLPG
                     RRVAHAAADVEAIADALDIDEFAVVGRSGGAPHALACAALLPDRTARAAALVGLAPRDA
                     QGLDWFDGMTEANVREYINAAAGQGQLTTALEMRSITIRSDPRRSVADMRHDLPKPDRG
                     IVADAGIRAMLERNFEEALRSSADGWVDDVMAFSTDWEFRPEDITAPVLLWHGEQDVFA
                     PVQHTRWLAERIPGAQLIVERGAAHFG"
     misc_feature    complement(9346..9348)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(9495..9929)
                     /locus_tag="DWB77_RS31925"
                     /old_locus_tag="DWB77_06441"
     CDS             complement(9495..9929)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492606.1"
                     /locus_tag="DWB77_RS31925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06441"
                     /product="CoA-binding protein"
                     /protein_id="WP_246033699.1"
                     /transl_table=11
                     /translation="MHPEQSEQPEQSEQDTIRKILTESGDTWAVVGLSSNQGRAAYGVA
                     KVLQRFGKRVVPVHPKAETVHGEQGYASLDAIPFPVDVVDVFVNSELAGEVADQAVAAG
                     AKAVWFQLGVVDQDAYDRTRAAGLDMVMDRCPAIEIPRLG"
     gene            complement(10001..10954)
                     /locus_tag="DWB77_RS31930"
                     /old_locus_tag="DWB77_06442"
     CDS             complement(10001..10954)
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941191.1"
                     /locus_tag="DWB77_RS31930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06442"
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_120725486.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.6e-27, bitscore:
                     93.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.8e-13,
                     bitscore: 49.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAWNQALDAAGIRAPGLRDDYTRQRELAARFKRSAYLAARLLLP
                     RPLFPHVVAATAFMHHSDNLLDSGPLDARAEAYGAWEREVRDGLADGDSGHPVIRPLLN
                     TITAHPRLRDHVEDYLRTARTDLDFTGFATEADYQAYIDAYSLPAFMLVACLLGPDGDA
                     TEFRAACRTYIDAAQRIDFVNDLAEDLADGRLTLPREELERCGVTREDLEQARDLPGTR
                     ALIAAALDRARTTLAASSPLTHLVPEPGRPLVRALIAFDTLTLTAATHKGPALLKSPAR
                     PSVRGAVGVLVREYGAARRVGRGTGAGRHADVTAGP"
     gene            complement(11021..13441)
                     /locus_tag="DWB77_RS31935"
                     /old_locus_tag="DWB77_06443"
     CDS             complement(11021..13441)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019735.4"
                     /locus_tag="DWB77_RS31935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06443"
                     /product="polysaccharide lyase 8 family protein"
                     /protein_id="WP_120725488.1"
                     /transl_table=11
                     /translation="MSLDRRDVLRFGATAAVAAAVPLGLGEPASAAPLGPSDAGDHARI
                     VAAYRELQIGVNRPSLRRDRALAALDQVALAHDAAMDVTRDQLWADLPTGPGSTYFPTM
                     YYRLRTIAVAWATPGSALSARPDQPERIMTALTTLYRTQYNENTAEIGNWYSYEIGVPY
                     WLLQTVVALGDRLPAADLERVLRPVLRFVADPNRRTNTPELVETGANRADKALITVVSG
                     ALAGDSARVAAGLAAVTDVAGQGAADLTRRSTHGDGYRTDGSFIQHEVVPYPGHYGLVL
                     LSAIAALTHVTDATSTQLPSAVREMFESTVTQVYAPFLFAGSMMEPVRGRMLSRQGETG
                     HDAGHQFIAAVVLLARTAAEPARSRLTSLAARWIAEGTWAPYLDVADVGRYSGGLQPVG
                     VPEVEFAEQLTSRSRAATTAVREHRVFPQMDRMVHSTPGWSASLGTGSRRICRYESING
                     MNLHGWYTGDGVLYTFLPGRQGHYSDAYWPTVDATLLPGTTEKDAPPPPLLADPPRTAT
                     SYAGGVRFDDAHGAHGLDFVSQDGTLSARKSWFFTPDAVICLGAAIADASGAPVRTAIE
                     NRNLGEEGSARLLVNGRPDRSLPGTPSAVADARWLHLEGTAGYVLLDGPGRGPLTLLRE
                     DRAGSWLGIDTGANTHGTATRYTRRYQKIVLDHGVHPTDASYAYAVLPGASVDHTRRAC
                     GRWSVLANTGRAQSVCLDGQLTAASFFTAGTVERVRVSGAAAMMWGRTAIGWTFALSDP
                     TQTQDTVRVTVEGAGHRLRHADPSVTVVATHPRLVVDIAVAGSFGATHTFTTA"
     gene            14040..16106
                     /gene="fusA"
                     /locus_tag="DWB77_RS31940"
                     /old_locus_tag="DWB77_06444"
     CDS             14040..16106
                     /GO_function="GO:0003746 - translation elongation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006414 - translational elongation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fusA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007267309.1"
                     /locus_tag="DWB77_RS31940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06444"
                     /product="elongation factor G"
                     /protein_id="WP_120725490.1"
                     /transl_table=11
                     /translation="MRTPIRPLTATPLRALRNLGILAHVDAGKTTLTERILFATGAVHK
                     RGEVHDGTTVTDFDAQERDRGITIFAAAVSCDWDGHHINLIDTPGHVDFADEVERSLRV
                     LDGAVAVFDAVAGVEPQSESVWRQADRHGVPRIAFVNKMDRAGADLDTAVASIKDRLGA
                     VPLVVQLPVGREDGFTGVIDLVRMRTLLWDGDTRTEGPVLEEWSDDAAGRRRLLEETVA
                     ELHPDALEEFCGASELSEETLVRALRELTLGGDAVVVLCGSAYRNRGIEPLLDAVLAYL
                     PSPLDMPPVRGTADGREQERAPDPAAPFAALAFKVNSTARGRLTHLRIYSGTLRKGAWV
                     RDAASGRTERVGRILRVQADRHEEKEEAMAGDIVAVVGLKTARPGATLCAPDAPVLLEP
                     PSVADPVVSVAVEARLAGDTGRLAAALARLAEEDPSLVVRSDPETGQTVLSGLGELHLE
                     VAVEKIRRDLDVEVNVGRPQVSYRETVLRGVSGVVYRHVKQDGGAGQFAHIVLDVEPME
                     EGGFAFRSTVVGGRVPQEYARAVEAGCRDALAEGPLGGHPVTGLRVTLTDGAIHSKDSS
                     EMAFRTAGRFGLREALRASEMGLLEPVAEITVTVPEDGVGGVLGDLAARRGQVTASTAG
                     AGSAVITATVPLAELFGYASRLRGRTQGRGTFTTRPAPLAPVPTAVAQALLAR"
     gene            16228..16854
                     /locus_tag="DWB77_RS31945"
                     /old_locus_tag="DWB77_06445"
     CDS             16228..16854
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017948434.1"
                     /locus_tag="DWB77_RS31945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06445"
                     /product="YigZ family protein"
                     /protein_id="WP_120725492.1"
                     /transl_table=11
                     /translation="MQEQYRTVARAGVHESEINRSRFICALAPAATEQEAQDFIARVRK
                     EHPTAGHHCFAYVIGADASVQKASDDGEPGGTAGVPMLQMLTRREVRYAVAVVTRYFGG
                     VKLGAGGLIRAYGGVVGEALDELGTIVRRRFRLATVTVDHQRAGKLENDLRATGRAVRE
                     VAYAEAVTIEIGLPEADIEAFRGWLADATAGTATLELGGEAYGDA"
     gene            16962..18116
                     /locus_tag="DWB77_RS31950"
                     /old_locus_tag="DWB77_06446"
     CDS             16962..18116
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230: Nuclease SbcCD,
                     D subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970568.1"
                     /locus_tag="DWB77_RS31950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_06446"
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="WP_120725494.1"
                     /sec_met_domain="Metallophos_2 (E-value: 9.5e-07, bitscore:
                     27.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFLHTSDWHLGRSFHRVDLLGAQAAFVDHVVATVRDRGVDAVLV
                     AGDVYDRAVPPLAAVDLFDRALHRLADLGVPTVMISGNHDSARRLGVGAGLIQRAGIHL
                     RTDPAGCGTPVMIGDVACYGLPYLEPALVRDELGAPKGGHEAVLAAAMDRVRADLAERP
                     HGTRSIVLAHAFVAGGEPSDSERDITVGGVAAVPAGVFDGVDYVALGHLHGSQVITERV
                     RYSGSPLAYSFSEADHRKSMWLVDLAADGTVEAERIDCPVPRPLARIRGRLDALLDDPA
                     LARHEQAWVEATLTDAARPADAMARISARFPGTLSLAFDPEGADGEPHTSYAQRLSGRS
                     DQQIAEDFVAHVRGGSGPDDHERTVLRGAFDAVRVDDGVREVAR"
     misc_feature    complement(19165..19179)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.09"
                     /tool="antismash"
     misc_feature    20910..20924
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.18"
                     /tool="antismash"
ORIGIN
        1 acagaagcgc ggttcatcgc gaacgaaacc actcgtgcgg gtgatttcta cgccgtcgcc
       61 gaacctgggc accggccaag gccgttgtgg tgtcccgggg aggcggcagt ggtcggaccg
      121 gtcgctcatg gcgccgaagc gcccaggggc acggcgtgcg gccgaacggc acgacgcacc
      181 aaacagccca agcagtgttc tacccagccg tgttccgcac agcgatccca ccagaccctg
      241 ctgcgaagac ggcgcttcga tccgaaaggc gctcacgtgg aagctctcgt ctcggcggcc
      301 gtacggcccg gccccgccac ccaccggtcg gccgaccggg gaccgtcgct ggcgcggcgg
      361 gccgcggcgc agaacgccgg gaaggctccg gcgaacctga cccgggcgat ggcggcctgc
      421 ggcgacccgc acgttcccgc cgcctccgcg ttccagtcgg cgctctgacg ggcggaacga
      481 ctccccccat ggaccgcgcg attgtgcccg ccctgtcgca gttcgtgctg aaggtacaca
      541 gccgctgtga tctcgcgtgc gaccactgtt acgtctacga gcacgcggac acgagctggc
      601 ggggaaggcc ccgggccgtc tcgccggaga tcctcgccca ggtggcgaac cgtatcgccg
      661 agcacgcccg ccgccatcga ctccccaccg tccacgtcgt cctgcacggc ggagagcccc
      721 tgctcgccgg ccccgaccgg ctgcgcaccg ccgccgacga actgcgccgg gccctgcacg
      781 gagtgagcgc cctcgatctg cgcatgcaca ccaacggcgt gctgctcgac gaggagttct
      841 gcgagctctt cctcgaactc ggcatcaagg tcggggtgtc cctcgacggc gacaaggtct
      901 ccaacgaccg ccaccggcgc tacgccgacg gccgcagcag ccacgccaag gtcatccggg
      961 cgatcgagct cctcaaccgc ccccgctacc ggcccctctt cgccggcctg ctctgcacca
     1021 ccgacgtcga gaacgacccg gtcgcggtgt acgacgccct ccttgaactc acgcccccgc
     1081 gcatcgactt cctcctcccg cacgccacct gggacacccc gcccccgcgc cccggcggcg
     1141 ctcccacgcc gtacgcggac tggctcgacg cgatctaccg gcgctgggac gcggcgggcc
     1201 ggcccgtgcc ggtccgcatc ttcgactccg tactgcgcac cctgcggggc gagagcagtc
     1261 tgaccgagtc gctggggctc gcgcccgccg acctcgtcgt gatcgagacc gacggcacct
     1321 tcgagcaggc cgacagcctc aagacctcct acgacggggc tccggccacc ggcatggacg
     1381 tcttccggca ctcgctcgac gacgtcctcc agcaccccgg catgctcgcc cgccaacagg
     1441 gcgccgagca gctctgcgcc cagtgcaggg cctgcccggt cgtcgagtcc tgcggcggcg
     1501 gcctctacgc ccaccgctac cggaccggca acgccttcga caatccctcg gtgttctgcc
     1561 ccgatctgtt ggccctggtc accaccatcc gcgacaggga ggccgccgtg cccgcaccga
     1621 ccccgcagtc cgcccaactg cccctggacg agcgggactt cgaggagctg gcggccggct
     1681 tcggcggggc ggacaccgtc gggcgcctcg cggccgccca gctcgacctc aaccaggaac
     1741 tcctcgccgc cgtcagcgcg cagcgcatcg cgctctcgga ccgcgaggcc gccgaggcct
     1801 gggaggtcct gacggacctg gacgccgagg tccccgacga actcgccggc gtcctcgccc
     1861 acccctacac caggccctgg gcgctcgatg tgctcggggg ccgggcggcg cccgcgggcg
     1921 gcctcgccga gatcgccgcc accacggccc tgcgcgcccg gctggagcgg accgtcacgg
     1981 tgccgctgcg cgacacgacc ctgcgcctgc cgggcttcgg caccgtgcgg ctcgacgtcg
     2041 ccgccaccca cgccgaagtg acggcgggcg ccgacgggtt caccgtgcgc gccggtggcc
     2101 gccggctcga catcggctgg cacgagggcg tggacgggct caccccgcac tggcggcccg
     2161 tacgcctctt ccagggcgag ggctggaacg tggcgatcga ggacaccgac ccgctgcggg
     2221 actgccacga gtggcccgtg gccgagcggc tcccggtcgg cgaggccaaa ctctggtccg
     2281 aggacctcac cggcgcctgg tccctgatcc ggcgcgaact gcccgcctac gccgacggcg
     2341 tggcggcggg gctgcgtctg atcacccccc tgcatgcgcc ggacggcagc gatgtcagcg
     2401 ccgcctgcaa ggacgcctgg ggggcgatcg gggtggccag gcccgcctcc cccgaacagc
     2461 tcgccctctt gatcgtccac gagttccagc atgtgaagct cgccgccgtc ctcgacgccg
     2521 tcgacctgta cgacaaggcc gatcgcggcc gctactacgc cccctggcgc gaggatcccc
     2581 gcccgatcgg cggcctgctc cagggaacgt atgcccacat cgcggtgacc gacttctggc
     2641 gggtgcgccg cgagacggct ccgctcgccg ccgaacgcgg cgccgccgag gccgagttcg
     2701 cccgctggcg gcagcagacg gcacgggccg tggaggtgct gctcggctcg ggatccctca
     2761 cggacctggg ggaacgcttc gtcgggcgca tgggcgagac cgtggccgat tggcgggacg
     2821 agccggtctc acccgccgcg ttctccgccg cggaagagtc cgcacgtcgt caccgggtcg
     2881 cctgggaggc ccgtgccgaa ggccgaaccg cctgaattta ccagcgaatt gagcgaattc
     2941 tcccctcatt tgattgatcc actcccggag cgccgcatga tttcggtcat gatctgatcg
     3001 aaactccctg agtggatctc ccccgggttt gttcgttctg ttccgccgga gaatcctccg
     3061 ttcctacact gaggtcccat ccacttggac cgggggagac agtggtgcag ggatcagtgg
     3121 gggccggggg agacgagcaa catccctatt tctttctcag ctacgcgcac acgccgaaga
     3181 gcgaccccaa ggacaaggac ccgaacctct gggtccagcg gttcttccgg gacctctgcg
     3241 cccatgtgat gcagttgacg cccctcccgg ccggcagcgc cggcttcatg gacgtgcaga
     3301 tgcagcccgg ggaggggtgg caggaacggc tctcggaggc gctcgccttc tgcaaggtgt
     3361 tcgtaccgct ctattcgccg cgctatttcc tcagcgaaca gtgcggccgg gagtggttcg
     3421 ccttctccag ccgggccgcc gcgcaaaaca cccgtaacag cagcaacaac agcaaccccg
     3481 tcaccggaat agtgcccgcg ctgtgggtgc ccgtgcccac ccgacagctc ccgcagcccg
     3541 cggaacgcct tcagttcaac cacgccacgt tcggcgacga atacgccgac gagggcttct
     3601 atggactcat caaactcaac tacctgcggg accagtacga acgtgccgtc taccggctgg
     3661 ccaaacgcat cgtcaacgtg gcccagcaga cccaactgga gcccggcgac ccccaccagg
     3721 actacgccaa ggtgccgccc gccttcggcc cggccggtgg gcccgcccgg gaaatggagg
     3781 tcgccgtcct cgcctgctcg cgctccagcc tccccaccgg acgcagcccg gactgctacg
     3841 gaaccgaggc cctggactgg aacccgtacc acccgacgtc ctccagaccg ctcgccgacc
     3901 acaccgtcga cgtcgtacgc aatctgaact acaccgtgca cctcagcgac ttcgaggccg
     3961 aaccccaccg gctcctcgcc tccggcccac ccggacccgg tctgctgctg ctcgaccgct
     4021 gggcgctgga cgcccggcgc cgccgcgaac tgctcgacca gctcggcgcc agccgacggc
     4081 cgtggatcag cgtcatggtc ccgggcaacg tggcggaccc ccaatcccgc gcccgcgacg
     4141 aggagttgtc gtcgcagacc gacgccgcgc tctccacccg ggtcaacgag agcgacggac
     4201 accgcacacc cagcggcgga ctgcccaccc tcgaagcctt cagcaaggcg atcccgggcg
     4261 ccgttaaggc ggcggtacgc cactacgagg cccatgcgcc gacctatcca ccgcccggca
     4321 gcggcgggcg gatgccccgg gtgcttccgg gcggcatcgg ctacggcgca ccgggcccca
     4381 ctggccgcgg tcgcagcacg gaccaggaga agaaccacgg tgataaggcg gagggctcat
     4441 cagatgactg agaaccgcaa cgggaccgtc gtcacgttct actcgtacaa gggcggcacc
     4501 ggacggacca tggcgctggc caactgcgcc tggatcctgg cggccaacgg gtaccgggtg
     4561 ctggcggtcg actgggacct ggaggcgcca ggtctgcacc ggttcttcca cccgttcctc
     4621 gacctcgccg acctggaggc gaccccgggc ctgatcaacc tgatcaccga ctaccaggac
     4681 gaggcgcgcc ggcccgccga ccgcgacccc gactggcacc gcgactacgc ccgggtccgc
     4741 ccccacgcca cctccctcaa ctggaacttc ccccagggcg gcagcctcga cttcctctcc
     4801 gccggacggc gcaaccgcga ctatccgtcc atcgtcggca agatggactg ggacgacttc
     4861 cacgagcggt tcggcggcgg ccagttcttc gacgccatgc gcgacgacat gcagcgccac
     4921 tacgactaca ccctgatcga cagccgcacc ggcctgagcg acatcgccga catctgcacc
     4981 gtgcagatgc ccgaagtcct cgtcgtctgc ttcaccttga gcgaccagag catcgacggc
     5041 gcctcggcgg tggcccgcga catcgaggag cgctaccacg agcggcgcat ccgcatcctg
     5101 cccgtcccga tgcgcatcga cgacggcgag aaggagaagg ccgacgccgg ccgggccctg
     5161 gcccgcgaga gcttccccgg cttccccagc ggcctgagcc ccgaggaact gggcaactac
     5221 tggggcaccg tggaggtccc ctaccgcccc ttctacgcgt acgaggagat cctcgccacc
     5281 ttcggcgacg cgcccaacgt ctccagctcc atgctcagcg cctgcgaacg gctcacctcg
     5341 gtcctcaccg gcggcctggt gaactcgctg ccgcccatcg acgaggccga ccggctcacc
     5401 catgtcgccg cctacacccg gcgccggccc atgccgccgt ccaacctggt gcttacccat
     5461 gtcgccgagg accagatgtg ggccgactgg ctggtgtacg tcctcaccgc ggccggtttc
     5521 cacgtcgtgc ctgtcgatgt ccgcgccccc cgatcgagcg ccacggaggc cgagttcacc
     5581 tccggcgccg gctatcgcgt gataccggtc gtctcccagg cctacctcaa ctccgagcgg
     5641 gccaggagct cctgggagtc cgggaccggc ctcgacatct ccggcgggcg gcgccacatc
     5701 ctgccggtgc gcgtcggcga cgtacggctc ggcccgccgc tgagcagccg gggcgtcatc
     5761 gacctcgtac ggctcgacga ggccgacgcc ggtgccgccg tgctcaacgc cctcgaccgc
     5821 tccgaggcgg tcgccgccct ggcctccggg cctcccgggc cgcgctaccc cggcagcgtc
     5881 cccaaggtct ggaacgtacg gccccggcac gcctggttca ccggccgcac ctccgtcctg
     5941 gagcggctgc gtgaccaact gcgcggtgac agccgctccg cccagcgctt cccgcaggtc
     6001 ctctacggcc tcggcggcgt cggcaagacc caggtcgcgc gggagtacgc ccaccggttc
     6061 cgcgccgact acgacctggt gtggtggatc gaggccgagc agcccgaccg ggtggtgtcc
     6121 tcgctcgccg agctggccgc cgagatggac ctcagggccg gtgacgtggt ggccgaggcc
     6181 gcgaccgccg ccctccaggc gctgcggcgc ggcgcgccct actcccgctg gctgctgatc
     6241 ttcgacaacg tcgaagacct cgaccgggcg ctgaaactgc tccccgagga catcgagccc
     6301 atccccggcg agacctatgg tcacatcctg gcgacctgcc gcaacaagcc cgcctccacc
     6361 aaggtggagg ccatcgaggt agaggtcttc acccgggccg agagcatcga gcacctgtgc
     6421 cggcgggtca ccaaactccc gaccgccgac gccgaccggg tcgccgacgc cgtcggtgac
     6481 ctgccgctcg cggtcgaggt cgccgccgcc tggctcgccg agacggcgac ccccgtcgac
     6541 gcctatgtgg aacagctcag ggagcagagc accaaggtcc tctcgctcgg caagcccgag
     6601 gactactcgg agcagatcgg cgcgacctgg aacatctcca tcagtcggct gcgcgatgaa
     6661 tccaaggcgg cggtacgcct gttggagctc tgctcgttct tctccgccga gccgatctcg
     6721 atgcggctca tcggcagcga ctcgatgttc gagtcgctcc tgccgtacga cccggacctg
     6781 cgcgagcggt acatgctggg caaggtcatc cagaccctga accgtttcgc gctcgccaag
     6841 gtcgaccccg ccgacagcag catccaggtg caccggctcg tccaggcggc cgtaagggca
     6901 ggcctcagtg acgacgaggt cgacacagcc aagcacgagg tgcaccgcat cctcgccgag
     6961 gcccggcccg tcgagggcgt cgaccgcgac aaccccgtca acgaccccaa gagctggccc
     7021 agtttcgaac tgatctggcc gcacctgagc gcctccggca tcgccgactg cgacgaggag
     7081 aaggtccgcc agctcatggt cgaccgcatc cgctatctcc tcaagcgcgg cgagctggag
     7141 agcgcccggg tgctcggcac ccagctcaac aaggtctgga cccgcgaact cggcgagaac
     7201 gacctccaga ccctcaacat ccgcttcgag ctggccaacg cgctgcgcgc ccagggcaag
     7261 taccaggagg cccgggcgat ggacgaggac accctcgccc gtcagatcag cgtcctgcgc
     7321 aaggaccacc cgggcgacga ccaccccagc atcctcatca ccaccggcag cctcgccgcc
     7381 gacctgcgcg ccctcggccg gttcgacgag gccctcaccc gggacctcac gatctaccac
     7441 ggccttcgcc agatcttcgg cgagaaccac ccgcgcaccc tcatcgcggc caacaacctc
     7501 gccatcgact accggctcag cggcgacagc gaggctgcgc gcaggctcga cgaggagacg
     7561 gtggaacgcc gcagcgccct cctcggcgag gaccacccct tcaccctcac caccaagggc
     7621 cacctggggc gggacctgcg cgagagcggg gagtacgccg cctcggtaca ggtgctgcgc
     7681 gaggtggtct ccgcgttcga gcgggtgctg aacgcggatg tgcccgaggc gctgcgcacc
     7741 gccaagagcc tcgccgtgtc cctgcgcaag gcgggccatc cgcacgaggc gaagcggctg
     7801 accgaggaga cgtacaaccg ctaccggggc cggtacggga ccaaggcgcc ggacgcgctc
     7861 gcctgctgtc tgaacctggc ggcggacttc tcggcgaccg gcgacaagca ggccgcctac
     7921 gacctctccc tccaggcgct cgagggctac cagggcaccc tgggcgagga gcaccccttc
     7981 accctggcct gccgcaacaa cgtctacatc tatcagcggg gcctgggggc agccgaggag
     8041 gcggcgcgcg gcggcgagga cgtgcgggcg gccctggagg aagtcctggg ctcacgccac
     8101 ccgttcaccc tctccgcggc gatcaacctg gccaacgcct acggcgacat gggccggccc
     8161 gacctggccg aacgctggga acggaccgcg ctcaagggcc tgttggagcg cttcgggccc
     8221 acccaccccg atgtgctggc ctgccgctcc aacctggcga tcacgctgcg ggccgccggg
     8281 cgcgaggacg aggcgcagcg gctgcggacc tccatcctgg aacccgccgc gaaacagctg
     8341 ggcgtggacc atccgatcgc ggaggcggcc cgggcctggc gccgcatcaa ccgcgacctg
     8401 gagccgcagc cggtgtgacg ttctccgggg agcgcccggg ccgcgacggc ccgccgctcc
     8461 ccggcccgcc cgtacggggc cggcgccccg gcgcctcctg actcgcgcgc cttcagccgc
     8521 tcaccaggtg gcccagctca ggaccctggt gagcacccgc agcgccccga agtgggcggc
     8581 gccccgctcg acgatcaact gggcgcccgg gatccgctcg gccagccagc gggtgtgctg
     8641 cacgggcgcg aacacgtcct gttcgccgtg ccacagcagg acgggagcgg tgatgtcctc
     8701 ggggcggaac tcccagtcgg tgctgaacgc catcacgtcg tccacccagc cgtccgccga
     8761 actgcgcagc gcctcctcga agttgcgctc cagcatcgcc cggatgccgg cgtccgcgac
     8821 gatgccccgg tccggcttgg gcaggtcgtg ccgcatgtcg gcgacggagc ggcgcggatc
     8881 ggagcggatg gtgatcgagc gcatctccag cgcggtggtc aactgccctt gcccagcagc
     8941 cgcgttgatg tactcgcgga cattggcctc ggtcatcccg tcgaaccagt cgagcccctg
     9001 ggcgtcgcgc ggcgcgagcc ccaccagggc cgcggccctg gccgtgcggt ccgggagcag
     9061 cgccgcacag gcgagcgcgt gcggggcgcc accggagcgg cccacgacgg cgaactcgtc
     9121 gatgtccagc gcgtcggcga tggcctccac atcggccgcc gcgtgggcca cccggcgccc
     9181 cggcagccgg tccgaatctc cgtatcccgg ccggtcgaac gtgatgaggc ggacgccgag
     9241 ccggtagagc accgcactgc gcggggccgg gccgagccgg ctccccgggg tgccgtgcag
     9301 caggaacacc ggtctgccct tcgggttccc ataattctcg accgctaagt cccgcccgtc
     9361 cctggtacga atcagctccc ccaactggtg cctcccccta ggtctggttg gcgccagtat
     9421 gagcgtgtgc gattcagtgg tacataccca cactcgccga atgcgcgacc gtggcccgct
     9481 ccgctcggcc ccgctcagcc gaggcggggg atctcgatcg ccgggcaccg gtccatgacc
     9541 atgtcgagcc cggcggcgcg cgtgcggtcg tacgcgtcct ggtcgacgac cccgagctgg
     9601 aaccagacgg ccttcgcccc ggcggcgacg gcctgatcgg ccacctcacc ggcgagctcg
     9661 ctgttgacga acacgtcgac gacgtcgacg gggaagggaa tggcgtcgag cgaggcgtac
     9721 ccctgctccc cgtgcacggt ctccgccttg ggatgcacgg gcacgacccg cttcccgaac
     9781 cgctgaagca ccttggccac cccgtaggcg gcccgcccct gattggagga gagccccacg
     9841 acggcccagg tgtcaccgct ctcggtgagg atcttgcgga tggtgtcctg ctcggactgc
     9901 tcgggctgct cggactgctc ggggtgcacg gtggctcctg ggggtcgggg gtggcccatg
     9961 gtcactgggg caacgtccgc accgcccggc cgcattccgt tcagggcccc gcggtgacgt
    10021 ccgcgtgccg tccggcgcct gttccccgcc ccacccgccg cgccgccccg tactcccgca
    10081 ccagcacccc cacggccccc cgcaccgacg ggcgggcggg ggatttcagg agggcggggc
    10141 ccttgtgggt ggccgcggtc agggtgaggg tgtcgaaggc gatcagggcg cggaccaggg
    10201 ggcggcccgg ctccgggacg aggtgggtca gggggctgct cgcggcgagg gtggtgcggg
    10261 cccggtcgag cgcggcggcg atcaacgcac gggtgccggg cagatcgcgg gcctgctcca
    10321 ggtcctcgcg ggtgacccca cagcgctcca actcctcgcg gggcagggtg agtcgaccgt
    10381 cggcgaggtc ctccgcgagg tcgttgacga agtcgatccg ctgggcggcg tcgatatagg
    10441 tgcggcatgc cgcgcggaac tccgtcgcgt cgccgtccgg gcccagcaga caggccacga
    10501 gcatgaacgc gggcagcgag taggcgtcga tgtaggcctg gtaatccgcc tccgtggcga
    10561 agcccgtgaa gtccaggtcg gtgcgggcgg tgcgcaggta gtcctcgacg tggtcgcgca
    10621 ggcgggggtg ggccgtgatg gtgttcagga gcggacggat caccgggtgg ccgctgtcac
    10681 cgtcggccag gccgtcgcga acctcgcgct cccatgctcc gtaggcctcg gcccgggcgt
    10741 cgaggggacc gctgtccagc aggttgtcgc tgtggtgcat gaacgcggtc gccgcgacca
    10801 cgtgcgggaa cagcggtcgc ggcagcagca gccgggcggc cagataggcg ctgcgcttga
    10861 agcgtgcggc cagttcgcgc tggcgggtgt agtcgtcgcg cagccctggg gcgcggatgc
    10921 ccgcggcgtc gagggcctgg ttccacgcgc tcatcgatga cctctcccgg gatgtggatg
    10981 ccgggttcca gtggatcacg gccgcgcgag aggccaccgc tcaggccgtg gtgaacgtgt
    11041 gggtggctcc gaacgacccg gcgaccgcga tgtccaccac cagcctcggg tgggtggcga
    11101 ccacggtgac ggagggatcg gcgtgccgga gccggtggcc cgccccctcg acggtcaccc
    11161 gcacggtgtc ctgcgtctgc gtggggtcgg acagggcgaa cgtccacccg atggcggtac
    11221 gcccccacat catcgcggcg gcccccgaca cccggacccg ttcgacggtg cccgccgtga
    11281 agaacgacgc tgccgtcaac tgcccgtcca ggcacaccga ttgggcccgt cccgtgttgg
    11341 ccagtacgct ccaccgcccg cacgcccggc gggtgtggtc cacggaggcg cccggcagca
    11401 ccgcgtaggc gtagctcgcg tcggtcgggt ggacgccgtg gtcgaggacg atcttctggt
    11461 agcggcgggt gtaacgggtc gccgtgccat gggtgttggc gccggtgtcg atgcctagcc
    11521 agctgccggc gcggtcctcg cgcaggaggg tgaggggccc tcggcccggc ccgtcgagaa
    11581 gtacgtatcc ggccgtgccc tccaggtgca gccaccgcgc gtcggctacg gcgctgggcg
    11641 tgccgggcag ggagcggtcc gggcggccgt tgacgagcag ccgggcggag ccctcctcgc
    11701 cgaggttgcg gttctcgatg gccgtgcgca ccggggcgcc cgaggcgtcc gcgatggcgg
    11761 cgccgaggca gatcaccgcg tccggggtga agaaccagga cttcctggcc gacagggtgc
    11821 cgtcctgcga gacgaagtcc aggccgtggg cgccgtgggc gtcgtcgaag cgcaccccgc
    11881 cggcgtacga ggtggcggtg cgcggcgggt cggcgagcag cgggggcggt ggggcgtcct
    11941 tctcggtggt gcccgggagc agggtggcgt ccacggtcgg ccagtaggcg tcgctgtagt
    12001 ggccctgtcg gcccggcagg aaggtgtaga gcacgccgtc gcccgtgtac cagccgtgca
    12061 ggttcatgcc gttgatggac tcgtaccggc agatgcgccg cgaccccgtt ccgagcgagg
    12121 cggaccaccc gggggtgctg tgcaccatcc ggtccatctg cgggaacacc cggtgctccc
    12181 ggaccgccgt ggtggcggca cgcgacctgg acgtgagctg ttcggcgaac tcgacctcgg
    12241 gtacgcccac gggttgcagc ccgcccgagt acctgccgac gtcggcgacg tcgaggtacg
    12301 gcgcccaggt gccctccgcg atccagcgcg cggccagaga cgtgaggcgg gagcgggcgg
    12361 gttcggcggc ggtcctggcg agaaggacca cggccgcgat gaactggtgc ccggcgtcgt
    12421 gccccgtctc gccctgccga gagagcatcc ggccgcgcac cggctccatc atcgacccgg
    12481 cgaacaggaa cggcgcgtac acctgggtga cggtcgactc gaacatctcc ctcacggcgg
    12541 acgggagttg ggtggaggtg gcgtcggtga catgggtcag ggcggcgatc gcgctcagga
    12601 gcaccagacc gtagtgaccc gggtagggca ccacctcgtg ctggatgaag gacccgtcgg
    12661 tgcggtagcc gtcgccgtgg gtggagcggc gggtgaggtc cgcggccccc tgccccgcga
    12721 cgtcggtcac cgccgcgagg ccggcggcca cccgggctga gtctcccgcg agcgccccgg
    12781 acaccacggt gatgagcgcc ttgtccgcac ggttggcgcc ggtctccacc aactcgggtg
    12841 tgttggtccg gcggttgggg tcggcgacga agcgcagcac gggacgcagc acgcgttcga
    12901 ggtcggcggc cggcagacgg tcgccgagcg ccacgacggt ctggagcagc cagtacggca
    12961 ccccgatctc gtaggagtac cagttgccga tctccgcggt gttctcgttg tactgcgtac
    13021 ggtagagggt ggtgagcgcg gtcatgatgc gctcgggctg atcggggcgg gcggacagcg
    13081 ctgagccggg cgtcgcccag gccacggcga tggtcctcaa ccggtagtac atggtgggga
    13141 agtaggtgct gccgggcccg gtcggcaggt ccgcccagag ctggtcgcgg gtcacatcca
    13201 tggccgcgtc atgggcgaga gccacctgat ccagggcggc cagggcccgg tcgcgccgga
    13261 gcgacgggcg gttcacaccg atttggagct cgcggtacgc ggccacgatc cgggcatggt
    13321 ccccggcgtc cgagggcccg agcggtgcgg ccgacgcggg ctcaccgagc ccgaggggga
    13381 ccgcggcggc caccgccgcg gttgctccga agcgcagcac gtctctgcgg tcaagcgaca
    13441 tcgctcgtcc tcacatcgga ttcgggaggg cgaggaatca gcgccccatt gttcaactac
    13501 gtgaacgacg cccatgtacg agaacctcct gggcgcggcc aaggtagcct tgacgccgcg
    13561 cgggagtcaa cgcccttgcc gggtcggctt gttgggcggc gggcgcgccg gggcccaccc
    13621 atggcatgaa ccggcggcaa acctccgctc cggaaaaccc cgtgccctgc ccccgctccg
    13681 ctgcctacac tcgccaggcg cgccgccgag cagcggcggg caacacgccg cactcgagtg
    13741 acgagtgacg agaccgagtg aagagaaagg gggccgggtc atgcgtacgc agtacaccgc
    13801 ggccctcgcc ccctcgtgcc ggttcgacgt gattttggtg tctcgcgtcg gtcggtgacg
    13861 gccgcgcggc cctcaccgca ggtaagtgac gcagcgtcaa accccttgcc cacacgcccc
    13921 gttgtcgcac gatgacggct ccgtggggca gggccggtga cgccgtccgc aaatcgcgcc
    13981 gtccgcttcc gcggtctcct gagtcatctc agcgacagca ctcgaaaggg cctcaggcca
    14041 tgcgtactcc catccgaccc ctcaccgcga cacccctgcg cgccctgcgc aacctcggca
    14101 tcctcgccca cgtcgacgcc ggcaagacga ccctcaccga gcggatcctg ttcgcgaccg
    14161 gcgccgtcca caagcggggc gaggtccacg acgggacgac cgtcaccgac ttcgacgccc
    14221 aggaacgcga tcgtggcatc accatcttcg ccgccgccgt gagctgcgac tgggacgggc
    14281 accacatcaa cctcatcgac accccgggcc acgtcgactt cgccgacgag gtcgaacggt
    14341 ccctgcgggt cctggacggc gcggtcgccg tgttcgacgc cgtcgccggt gtggaacccc
    14401 agagcgagtc ggtctggcgc caggccgacc ggcacggcgt gccgcggatc gcgttcgtga
    14461 acaaaatgga ccgggcggga gccgacctcg acaccgcggt cgcctccatc aaggaccggc
    14521 tcggcgccgt gccgttggtg gtccagcttc ccgtggggcg cgaggacggc ttcaccggcg
    14581 tcatcgacct ggtgcggatg cgcaccctgc tgtgggacgg cgacacccgt accgaaggac
    14641 ccgtcctcga ggagtggtcc gacgacgccg ccggtcggcg ccgactcctg gaggagacgg
    14701 tggcggagct gcatccggac gcgctcgaag agttctgcgg cgcttcggag ctgagcgagg
    14761 agaccctggt gcgcgccctg cgcgagctga ccctcggcgg cgacgcggtg gtcgtgctgt
    14821 gcggctcggc ctaccgcaac cgcgggatcg aacccctcct cgacgccgtg ctggcctatc
    14881 tgccctcgcc cctcgacatg ccgccggtac gcggcaccgc cgacggtcgt gaacaggagc
    14941 gggcgcccga cccggcggcg cccttcgcgg cgctcgcctt caaggtgaac tccacggcgc
    15001 gcggccgcct tacccatctg cggatctact cgggcaccct gcgcaagggc gcctgggtac
    15061 gcgacgcggc gagcggccgc accgaacgcg tcggcaggat cctgcgcgtg caggccgacc
    15121 ggcacgagga gaaggaggaa gcgatggcgg gggacatcgt cgcggtggtc ggcctcaaga
    15181 ccgcccggcc cggcgcgacg ctgtgcgcgc cggacgcgcc cgtgctcctg gagccgccct
    15241 cggtcgccga tccggtggtg tcggtcgcgg tcgaggccag gctggccggc gacacgggcc
    15301 ggctcgcggc ggccctggcc cgcctggccg aggaggatcc gtccctggtg gtgcggtccg
    15361 atccggagac cggtcagacg gtgctctcgg gcctgggcga gctccatctg gaggtcgcgg
    15421 tggagaagat ccgccgcgat ctggacgtgg aggtcaacgt cggccggccg caggtctcct
    15481 accgcgaaac cgtcctgcgc ggcgtgagcg gcgtggtgta ccggcacgtc aaacaggacg
    15541 gcggcgccgg gcagttcgca cacatcgtcc tggacgtcga gcccatggag gaggggggat
    15601 tcgcattccg ctcgacggtg gtcggcggcc gggtgccgca ggagtacgcg cgggccgtgg
    15661 aggcgggctg ccgcgacgcc ctggccgagg gtccgctcgg cggccatccg gtcaccgggc
    15721 tgcgggtcac gctcaccgac ggggcgatcc actccaagga ctcctcggag atggcgttcc
    15781 gcacggcggg caggttcggg ctgcgcgagg cgttgcgcgc gagtgagatg ggactcctcg
    15841 aaccggtcgc ggagatcacg gtgaccgttc ccgaggacgg cgtcggcggc gtcctcggtg
    15901 atctcgccgc ccgccgaggc caggtgacgg cgtccaccgc cggcgccgga tccgcggtga
    15961 tcaccgccac ggttccgctg gccgagctgt tcgggtacgc ctcccggctg cgcgggcgga
    16021 cccagggccg gggcaccttc accacccggc ccgcaccgct cgcgccggta ccgaccgcgg
    16081 tggcgcaggc ccttttggcg cggtagccgc cgtccgcccc gccccggtcc gccggggcgg
    16141 ggcgggtggg acggcgccgc ctcgaaggct ccggctccgg ctccggctcc ggcggagctc
    16201 gcggccggtg ccgcataggg tggacggatg caggagcagt accgcaccgt cgcccgagcg
    16261 ggcgtgcacg agagcgagat caaccggtcg cgcttcatct gcgcgctcgc gcccgccgcc
    16321 accgaacagg aagcccagga cttcatcgcc cgcgtccgca aggagcaccc gacggccggg
    16381 caccactgct tcgcgtacgt catcggagcc gacgcctccg tacagaaggc gagcgacgac
    16441 ggcgaacccg gcggcaccgc cggagtcccc atgctccaga tgctgacccg gcgcgaggtg
    16501 cgctacgccg tggccgtggt cacccgttac ttcggcgggg tcaagctggg cgcgggcggt
    16561 ctgatcaggg cgtacggagg cgtcgtcggc gaggccctgg acgagctcgg caccatcgtg
    16621 cgccgcaggt tccgcctggc caccgtcacc gtcgaccacc agcgcgccgg gaaactggag
    16681 aacgacctca gggcgaccgg ccgcgcggtg cgcgaggtgg cctacgccga agccgtcacc
    16741 atcgagatcg gtctccccga ggccgacatc gaggccttcc gcggctggct cgccgacgcc
    16801 acggccggca cggccacgct ggagctgggc ggagaggcgt acggggacgc ctgagcagta
    16861 cgacacccga cagccgcccc gtgccgtccg agccgccggg ggcgggtgga tgtttccgtt
    16921 accgcccgtg atgtcagacc ccaccgttac cctcgaggat catgagattc ctgcacacct
    16981 cggactggca cctgggccgg tccttccacc gggtcgatct gctcggtgcc caggccgcgt
    17041 tcgtcgacca cgtggtggcg acggttcgcg accgaggtgt ggacgcggtc ctggtcgcgg
    17101 gtgacgtgta cgaccgagcg gtgccgccgc tggccgccgt cgacctcttc gaccgggcgc
    17161 tgcaccgcct cgccgacctc ggcgtgccga ccgtgatgat ctccggcaac cacgactcgg
    17221 cgcgcaggct cggagtgggg gcgggcctga tccagcgggc cggaatccat ctgcggaccg
    17281 acccggcggg gtgcggcacc ccggtcatga tcggggacgt ggcctgctac gggctgccct
    17341 atctggaacc cgcgctggtc cgcgacgaac tgggcgcgcc caagggcggc cacgaagcgg
    17401 tgctcgccgc ggccatggac cgggtccggg ccgacctcgc ggagcgcccc cacggcaccc
    17461 gctccatcgt cctcgcgcac gccttcgtgg ccggcggcga gccgagcgac agcgaacgcg
    17521 acatcaccgt cgggggagtg gccgccgtgc ccgccggagt cttcgacggc gtggactatg
    17581 tggccctcgg gcacctccac ggcagccagg tgatcaccga acgggtccgc tactcgggct
    17641 ccccgctcgc ctactccttc tcggaggccg accaccgcaa gtccatgtgg ctggtggacc
    17701 tcgcggccga cggaaccgtc gaggccgagc ggatcgactg cccggtgccg cgccccctgg
    17761 cccgcatccg gggccggctc gacgcgctcc tcgacgaccc ggccctggcc cggcacgaac
    17821 aggcctgggt ggaggccacg ttgaccgacg ccgcccgccc ggccgacgcg atggcgagga
    17881 tcagcgcccg cttccccggc accctgagcc tggccttcga ccccgaaggg gccgacggcg
    17941 agccgcacac ctcgtacgcg cagcgcctca gcggacgcag cgaccagcag atcgcggagg
    18001 acttcgtggc gcacgtacgc ggcggcagcg gccccgacga ccacgaacgg acggtcctgc
    18061 gaggggcgtt cgacgccgtg cgggtcgacg acggggtgcg cgaggtggcc cgatgaggct
    18121 gcaccgcatg cgggtcaccg ccttcggccc gttcgcggac agccaggaga tcgacttcga
    18181 cgcgctgtcc gccgcgggcc tgttcctgct gcacggtccc accggcgccg gcaagacctc
    18241 ggtcctcgac gcggtctgtt tcgccctgta cgcggcggtc cccggcgccc ggcagagccc
    18301 cgccaccccc ctgcgcagcg accacgccgc accggacgtc ttcaccgagg tgctgctcga
    18361 actgaccgtc ggcggaaggc ggttggagat cacccgccgc ccgcagcagg agcgccccaa
    18421 gaagcggggc agcggattca ccaccgagaa ggcgcagacc tggctgcggg agtacgaccc
    18481 ggcggccgga gcctggcggg ccctgagccg ttcgcaccag gagatcggcg aggagctcgg
    18541 acagctcatc gggatgagcc gggaacagtt ctgccaggtg gtgctgttgc cgcaggggga
    18601 gttcgccaag ttcctgcggt ccgacgccga agcgcgcgga aagctgctcg gcaggctctt
    18661 cgacacccgc cggttcgcgg ccgtcgagga ccggctcgcc gagttgcgca agaccgccga
    18721 gcgtcaggtc aaggacggcg acgaacgact gctcgccctc gcccagcgga tggcgcaggc
    18781 cgccggcgac accacggacg cccgcgcctg gccgctgccc gacgcgcggc ccggcgaccc
    18841 gggccttgcc tcggccgtcc tccagtgggc ggccgtcgcg cgctgcggcg cacaggaacg
    18901 cctcgacatc gccgaggccg ccgtggccac cgccgagagc cgccaggccg ccgcccgccg
    18961 cgtcgccgaa gagacccggc agctggccgc actccaggag cggtacgccc aagcccgctc
    19021 cagggccgat gagttggcgg ccggccgccc cgagcaggac gagctgaagg cccgcctgga
    19081 gacggcccgc aaggccgaac gggtcgcgcc cgccctcgaa tggcaggaac aggcccagcg
    19141 cgcccacggc gcggcgaccg ccgaacggga ccgctcccgc gcccggctgc ccccggacct
    19201 cgccgacgcc ggagcggaac aactcgccgc cctggaaagg cggatgcgcc aggacctcgg
    19261 agccctggag tccgcccgcc gggccgagcg ccgcagcgcc gagatcgacg aggagcgggc
    19321 ccgcctcgac cggcaggccc gcgccgacga ggacgtcctc accgacacca cggcatggct
    19381 cgcgggctgg gagaccgtcc ggctcgacca tcaggccagg atcgacaccg cccatgaagc
    19441 ggcggcccgc gcggaacagc tcgccggaca gctcgaaccg gccaggaacc gcctcgccgc
    19501 cgcccgtgaa cgcgacgcgc tccaggcccg ctcggccgag gcgacccgag cgcacgagac
    19561 ctcccgcgaa gccgccaacg ccgcccacga gcactggctg accctgcgcg aggagcggct
    19621 gcgcggcatc gcggccgagc tggccgcgcg gctccaggaa ggcgagccct gcccggtgtg
    19681 cggcgcggcc gagcacccgg cgccggcgcg ccccggcgcc ggtcaggtcg accgcgccgc
    19741 cgaggacgca gcccaccagg cataccgccg agcggaccgc acgcgcgccg aggcggaggc
    19801 cgccctgtcc ctggtacggg aggagctcgc gggcgcccgg gccgccgcgg gccacgcgga
    19861 cgtcgcccaa ctggccgacg aggcggagcg gttgcagcgg gcgcaccgcg aggcgcggga
    19921 cgcggcggcc gggctgcacg aggcccggct ggccctcgcc tcggcggagc gggagcgcga
    19981 gcgccgcctc gccgcccagc gcacggccca ggagaacgcc gcggcccgca ccgcgagccg
    20041 tgaggccctg gagcgtgaac agggcgcgct ggaaagggag ttgagcgagg cgcggggcgg
    20101 ggcgtccagc gtcgccgaac aggccgcact gctcgaacgc cgcgccgcga tcctcgccga
    20161 ggcggtggag gcggtccgtg ccgtcgagga cagcgccgag cggctcaagg aggccgacgg
    20221 gcggctatcg gaggcggcgt tccgggccgg cttcgacacc ccggccgcgg cggcggcagc
    20281 cctggtcgac gagcgcggcc agcgcgacat ccagcaccgg ctcgacgcct ggcagcacga
    20341 gcgggccacc gtcaccgcgt gcctcgcgga gccggagacg gccgcggccg gccgtgccgc
    20401 cccggcccgc accgcgcagg cggacgccga gtccgccgcc gccgaacgcg ccctgcgcga
    20461 cgccgcgtcg gccctcgccg ccgcccgggc ccgccgcgcg gaactgggca ccctgagcgc
    20521 ggcggccgtc gaggagaccc gcgcgatcgg cccgctgcgc gaggagtacg aacgggtcgc
    20581 ccgcctggcc gggctcaccg cggggacctc cgccgacaac gagcgcaaga tgcgcctgga
    20641 gtcctacgtc ctggccgccc gcctcgaaca ggtcgccgcc gcggccacgg cccgcctgag
    20701 gcgcatgtcg ggcgggcggt acacgctggt ccactccgac gccaggggag gccgcggacg
    20761 ttcgggcctg gggctgcacg tggtggacgc ctggacgggc cgcgagaggg acaccgcgac
    20821 gctgtccggg ggagagacct tcttcgcctc cctcgcgctg gcgctggggc tcgccgacgt
    20881 cgtcaccgac gaggtgggcg gggcgcgcct ggacaccctg ttcatcgacg agggcttcgg
    20941 cagcctcgac gacc
//
