LOCUS       NZ_CP032698            20528 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces hundungensis strain BH38 chromosome, complete genome.
ACCESSION   NZ_CP032698
VERSION     NZ_CP032698.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces hundungensis
  ORGANISM  Streptomyces hundungensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Relationship between Morphology and Antimicrobial Activity in
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2018) Microbiology and Molecular biology, Chungnam
            National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea,
            Republic of
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: RS HGAP Assembly v. v3.0
            Sequencing Technology             :: PacBio RSII
            Assembly Date                     :: 2018-07-09
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Genome Representation             :: Full
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003627815.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:42:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,472
            CDSs (total)                      :: 7,378
            Genes (coding)                    :: 7,187
            CDSs (with protein)               :: 7,187
            Genes (RNA)                       :: 94
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 191
            CDSs (without protein)            :: 191
            Pseudo Genes (ambiguous residues) :: 0 of 191
            Pseudo Genes (frameshifted)       :: 103 of 191
            Pseudo Genes (incomplete)         :: 121 of 191
            Pseudo Genes (internal stop)      :: 14 of 191
            Pseudo Genes (multiple problems)  :: 42 of 191
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4749417
            Orig. end                         :: 4769945
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032698.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20528
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phenazine"
                     /region_number="23"
                     /rules="phzB"
                     /tool="antismash"
     cand_cluster    1..20528
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="phzB"
                     /kind="single"
                     /product="phenazine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20528
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:10528](+)"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10528
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="phzB"
                     /neighbourhood="10000"
                     /product="phenazine"
                     /protocluster_number="1"
     misc_feature    complement(338..350)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.33"
                     /tool="antismash"
     misc_feature    1460..1475
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 23.75"
                     /tool="antismash"
     gene            1959..2969
                     /locus_tag="DWB77_RS21165"
                     /old_locus_tag="DWB77_04270"
     CDS             1959..2969
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014154632.1"
                     /locus_tag="DWB77_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04270"
                     /product="HNH endonuclease"
                     /protein_id="WP_246033592.1"
                     /transl_table=11
                     /translation="MIPEVETEVGRDELGDLRTDLDTDEVVTAWLMLALGKGREHAGND
                     GYDDSASQHYSWDDTVQNHARVSVGDVIALWDRKELIGVSVIEAIDIASAEKTLYSCPQ
                     CGRADIKRRQREKPAYRCGKCGHLFPTPRQKIKSVTTYRSVHGRRWMNGRGLLSGSELR
                     ALCDSPKSQLSMRPARWERLRQALLDATGQASTVKDIAAAARLAVAGGHRESVVRTRVG
                     QEAFRARLLREQGEVCAFTGPTPADALEAAHLYSYAESGEHHEYGGLLLRRDIHRLFDL
                     GHIAVDLASGTLDVIPSLHGYPCYAQLHGQPVAVQLRPEHRVWLDAHWLGKRPHA"
     gene            complement(3001..3231)
                     /locus_tag="DWB77_RS21170"
                     /old_locus_tag="DWB77_04271"
     CDS             complement(3001..3231)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531975.1"
                     /locus_tag="DWB77_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04271"
                     /product="hypothetical protein"
                     /protein_id="WP_120722737.1"
                     /transl_table=11
                     /translation="MTPETSSQDPVQEAKHRRAGIIAFAIGAAASLAFFAFFPGLPHVI
                     DWGAILVSLVVGALTRWAWLARTRRKRTSVR"
     gene            complement(3239..3559)
                     /locus_tag="DWB77_RS21175"
                     /old_locus_tag="DWB77_04272"
     CDS             complement(3239..3559)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018531974.1"
                     /locus_tag="DWB77_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04272"
                     /product="hypothetical protein"
                     /protein_id="WP_120722738.1"
                     /transl_table=11
                     /translation="MKIPTGCAFTHIIRGDGKSITYQNAGVDCGFVGALNSGFCNWRID
                     FTYADTNNRTYRTSRGRTHTECKIDPMRNNAPQKLPHYGKACAHLYVNGVRRVSQCHHI
                     TK"
     gene            complement(4165..4563)
                     /locus_tag="DWB77_RS21180"
                     /old_locus_tag="DWB77_04273"
     CDS             complement(4165..4563)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024275.4"
                     /locus_tag="DWB77_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04273"
                     /product="hypothetical protein"
                     /protein_id="WP_281280015.1"
                     /transl_table=11
                     /translation="MAVRTTRTTRPTRPTRPQRRRHPMKIRDLHDEFTADRAAAERAYY
                     GKYLTLEGVSIRTGESQYGTPVVDVSDVPGGPHLAIFVLPFDHRIKESFRIVRSVPLGV
                     PVTVKGECRVFSEDGTVLVIKECEILTP"
     gene            complement(4654..5208)
                     /locus_tag="DWB77_RS21185"
                     /old_locus_tag="DWB77_04274"
     CDS             complement(4654..5208)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0008753 - NADPH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050136 - NADH dehydrogenase (quinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014573.4"
                     /locus_tag="DWB77_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04274"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_162952584.1"
                     /transl_table=11
                     /translation="MTTNRTLVIVAHPNLTESRANANRLAEIKDLDNVTVHDLYATYPD
                     GKIDVEREHQLLREHDTIVLQFPVYWYNVTSMLKTWFDAVLIHGFAFTFDGSPSALSGK
                     KAWLAVTVGSTLETYATDGAARRPLDEYLAPVTQTLAFCQLDYQGFHAVYGMIFETSDE
                     TLALDAKEYRRLLANSETPVG"
     gene            complement(5494..6366)
                     /locus_tag="DWB77_RS21190"
                     /old_locus_tag="DWB77_04275"
     CDS             complement(5494..6366)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007499142.1"
                     /locus_tag="DWB77_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04275"
                     /product="oxidoreductase"
                     /protein_id="WP_120722741.1"
                     /transl_table=11
                     /translation="MTSPLQTLTLADDLRISRMGYGAMQLTGPGVYGPPKDRAEAIGVL
                     RAAVELGVTHIDTSDFYGPVVVNELIREALHPYPADLHIVTKVGVRRSAGGGWITSLDP
                     ADLKAQVHENLQHLGLETLDVVNLRTASFGGDASSVAEPFGALADLREQGLIRHLGLSG
                     ITESQLTQAQAIAPVVTVQNQYNLADRADDDLVDRCAEEGIAYAAFFPLGGGFSPLRSR
                     ILRDVAHRLGATEQQVALAWLLQRSPSMVLIPGTSSVAHLRENIAAAELRLPDEAVVEL
                     DTIGQIAER"
     gene            complement(6763..7875)
                     /locus_tag="DWB77_RS21195"
                     /old_locus_tag="DWB77_04276"
     CDS             complement(6763..7875)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_04276"
                     /product="hypothetical protein"
                     /protein_id="WP_120722742.1"
                     /transl_table=11
                     /translation="MPISIADKVLRLSMTTFPFIDASQFFPALSTYKVDRIFDLTEFEE
                     AMKHFFRGNPLFSKCHLVELTFDSPEDFPLASFQALLAEKYESYYDSFLVASVTYRSDP
                     HLQGIFTCVPFPLQDGYKCFHLHQALMKTLKTKQDGFQIAQGLAELGIRSDELADFVPP
                     VEAAPSGASKELPVSFTENSGSPVKIGSFLERMRGDLVERDSENMLILKNSLYSPKLPL
                     GNSLQFLTVPRGVVTQSTGIQIRDYYRAEEQRHMDVLSRIELRDEFIEAGRARIGNLIA
                     TPNVFCVNNYGNVSAHDGTDVQADHGTLMRYEWHMPTIVLGITAGERSGLSWTITVRDK
                     AFNFATVARTSPHGDIVGAAARTNPAASVA"
     gene            complement(7890..9254)
                     /locus_tag="DWB77_RS21200"
                     /old_locus_tag="DWB77_04277"
     CDS             complement(7890..9254)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1246: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_04277"
                     /product="2-polyprenyl-6-methoxyphenol hydroxylase-like
                     oxidoreductase"
                     /protein_id="WP_162952585.1"
                     /transl_table=11
                     /translation="MKRIGEHAVVLGASISGLLAARVLSEAFDRVTVVERDQLPDGQRT
                     QRRGVPQGRHAHGLLSKGAKIFEELFPGILDDFVAGGAPVIDGPAELRMRLGGHLLCMD
                     GEYADLSRTYQPSRPHLESRLRARIGALSRIKVIDQCQVTGLRTTSDNGTVTGVGVRYE
                     GSGSEDVIPADLVVDATGRSGRTTKWLVEMGYEPPAEERIDVDIMYTSRYLRPAPGSMG
                     REKVVIIGHAPGSPKGAEFLEEEDGRWVLTLIGYRDHHPPTDPAGWIEFARPLVPDHVF
                     AAIRDAEPLSEISAHRFPASVRRRYEKLTRFPRRLVVVGDAISSFNPIYAQGMTVASLQ
                     AMALRDSLSGDLDQVAQRFFRKAAKPIGVAWRMATGSDLALPQIEGPRPLPVRLINSYM
                     DKVLAAAETDMVVAEKFLKVQYLLEPPTTLCTPSTMRRVLAAHRRRRSSAPAPTH"
     misc_feature    9438..9452
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    9791..9805
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.74"
                     /tool="antismash"
     gene            10001..10528
                     /locus_tag="DWB77_RS21205"
                     /old_locus_tag="DWB77_04278"
     CDS             10001..10528
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phenazine: phzB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020132918.1"
                     /locus_tag="DWB77_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04278"
                     /product="PhzA/PhzB family protein"
                     /protein_id="WP_174248595.1"
                     /sec_met_domain="phzB (E-value: 3.6e-67, bitscore: 225.4,
                     seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADITGIAETAQSAESAATFAESRGESELRASNRAIVEQYMNTRG
                     QDRLRRHLLFTEDGTGGLWTTETGQPIVITGRDRLGDHGQWSLKCFPDWVWTNIEVFET
                     QDPNHFWVECDGEGTIRFPDYPDGHYRNHFLHSFLFENGKIKRQREFMNPCEQFRALGI
                     TVPQVKRADIPT"
     gene            10576..11741
                     /locus_tag="DWB77_RS21210"
                     /old_locus_tag="DWB77_04279"
                     /pseudo=""
     CDS             10576..11741
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013628.4"
                     /locus_tag="DWB77_RS21210"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04279"
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGNILVDIDRAKARHQPEWNNPAQVELVRAILSSVTPLVTAAQVE
                     DLRSHLARVATGEMQVLKAGDCAEDPAECTAGHIRSKTELIGLLAQNLETATGKRTLRV
                     GRIAGQFSKPRSSRFEKLGDAELPSFFGHMINGPEPTHESRRPDPLRMLTGYMAAREIM
                     TQLGWVGSVPRTDGSAVWTSHEALLLDYEISMLRELDGGRRLLSSTHWPWIGERTRQLD
                     GPHVALLAQVINPVACKVGPSMTPGEIAELCDRLDPEREPGRLSLIVRMGADLVADRLP
                     RLVEAVKSAGHPVVWLTDPMHGNTESAADGTKYRLVGNVAREVRGFRRVLDLAGVPAGG
                     SIWRRPPTT"
     gene            11766..12389
                     /locus_tag="DWB77_RS21215"
                     /old_locus_tag="DWB77_04281"
     CDS             11766..12389
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019886482.1"
                     /locus_tag="DWB77_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04281"
                     /product="isochorismatase family protein"
                     /protein_id="WP_120722744.1"
                     /transl_table=11
                     /translation="MTGIPPIAPYSLPPSHALPENSVRWTVHPDRAVLLIHDMQSYFLN
                     PFEDGMRSTLVHTVADLKKRCAALGVPVAYTAQPGSMTDEERGLLKDFWGPGMRTDEAE
                     RAIVPELEPDPEDWLSTKWRYSAFFKSELLQRMRALQRDQLIVCGVYAHIGVLSTALDA
                     FSNDVQPFLVADALGDFSAAHHRLTLAYAARSCAMVVRSEDVLA"
     gene            12386..14251
                     /locus_tag="DWB77_RS21220"
                     /old_locus_tag="DWB77_04282"
     CDS             12386..14251
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008740144.1"
                     /locus_tag="DWB77_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04282"
                     /product="anthranilate synthase family protein"
                     /protein_id="WP_120722745.1"
                     /transl_table=11
                     /translation="MSALLEHVLALEVPAFAIIHRPESGCAGTLDVLTGPVTEYKSLDD
                     IPLADDSVPGPALDTLVLVPYRQLADRGFAARDDATPLLAMSLTARDTVPVAEALARFP
                     QAPTELADGHFDVDDAAYAQMVRQIVTDEIGTGEGANFVMKRSFVADIGDYSLTSALSF
                     FRRLLEREEKAYWTFIIHTGRNTLVGATPERHISLAEGAAVMNPISGTYRYPSGGPTLQ
                     GVMEFLADTKETDELYMVLDEELKMMARLCDDGGRVHGPYLKEMARLAHTEYLIEGKTN
                     RDVREVLHETMFAPTVTGSPLESAAKVIWRHEPNGRGYYSGVAALIGRDAAGRQTLDSA
                     ILIRTADIDPGGRMNISVGATLVRHSDPMTEAAETRAKLATLLNALKSDPCSGYAADPE
                     VRAALDRRNDRIAGFWLRDRCERRPAGTPLDGATALVVDAEDTFTAMLDQQLRSLGLCV
                     EVRRFDEPYDVAAYDLTVFGPGPGDPRMASHPKIAKLRQSVDTALARHRPMLAVCLSHQ
                     VLSMKLGFDLHRREVPNQGVQREIDLFGLRERVGFYNTFAAHSAVGRRTVEGIGVVEVS
                     RDEQSGEVNALRGPGFASVQFHAESVLTVDGPRIIREAIQGVLGR"
     gene            14248..14601
                     /locus_tag="DWB77_RS21225"
                     /old_locus_tag="DWB77_04283"
     CDS             14248..14601
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) thio_amide"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001148.1"
                     /locus_tag="DWB77_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04283"
                     /product="hypothetical protein"
                     /protein_id="WP_120722746.1"
                     /sec_met_domain="thio_amide (E-value: 2.5e-12, bitscore:
                     45.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVDVVWWDLARSHQTIESLERDLRDSVEPWHEVRGLRLKLWIAD
                     RERGRWGAVMWWDSDVPADQPLPPNRAAELIGYAPDHRSAFDVAAVAEGIDALGLAFSA
                     EPSTTSAHVTELR"
     gene            14613..15434
                     /locus_tag="DWB77_RS21230"
                     /old_locus_tag="DWB77_04284"
     CDS             14613..15434
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019358208.1"
                     /locus_tag="DWB77_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04284"
                     /product="PhzF family phenazine biosynthesis isomerase"
                     /protein_id="WP_281280016.1"
                     /transl_table=11
                     /translation="MVVDAFAREPLRGNPVAVFFDSEDLTGETMQRIAQEMNLSEVTFV
                     LPAEQGGDARIRIFTPVNELPFAGHPMLGTAHALGRTWKRDRLRLETAMGVIPFELSTR
                     DGAAWVRMRQPVPSSKPYDLGADLLAALGVETSTAPVEIYHNGPRHVFVGLSDVGALSA
                     LHPDHRALSRFPDMAANCFARAGDGWQMRMFSPAYGVVEDAATGSAAGPLAIHLARHGF
                     AEYGQEIQITQGVEMGRSSVMRATAEGTGESIHSVHVGGHAAVVAEGRLHV"
     gene            15427..16086
                     /gene="phzG"
                     /locus_tag="DWB77_RS21235"
                     /old_locus_tag="DWB77_04285"
     CDS             15427..16086
                     /EC_number="1.10.3.16"
                     /GO_function="GO:0016682 - oxidoreductase activity, acting
                     on diphenols and related substances as donors, oxygen as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene="phzG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019884212.1"
                     /locus_tag="DWB77_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04285"
                     /product="phenazine biosynthesis FMN-dependent oxidase
                     PhzG"
                     /protein_id="WP_120722748.1"
                     /transl_table=11
                     /translation="MSERELLVSASEFESLSGKVDLPFPEYDQPPSEPLPLVRSWLDRA
                     RESGVREPAALALATADSRGRASNRTIAITEVTDAGLVFTSHSCSQKGRELAATGWASG
                     LLYWRETGQQIIISGPVVLLPDAESDALWSARPTPLHAMSTVTEQSEPLEDVEALRVRA
                     RRLERTGAPQPRPEFFVGYRLEPAVVEFWSASSDRLHRRLRYDRGPLQWRTSRLQP"
     gene            16193..17293
                     /locus_tag="DWB77_RS21240"
                     /old_locus_tag="DWB77_04286"
     CDS             16193..17293
                     /NRPS_PKS="Domain: AMP-binding (87-316). E-value: 2.8e-09.
                     Score: 27.9. Matches aSDomain:
                     nrpspksdomains_DWB77_RS21240_AMP-binding.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014053678.1"
                     /locus_tag="DWB77_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04286"
                     /product="phenazine antibiotic biosynthesis protein"
                     /protein_id="WP_120722749.1"
                     /transl_table=11
                     /translation="MPLSAEQILDLPFDVQPDPDDYLRAAMEWHFNPETGCAFWLDRAA
                     TLGFDPRADVKTYEDLRLFPNLAAELRDVRGEDLVPRGYGTRPDVVGFFESGGTTGAPK
                     RVVLMRDWLDRMVSWSNANLDRHGVPRGGNWLGIIPTGPHVVGTLFRQHAVTHGRHGFT
                     IDLDPRWVKRLIAEGQFGQVDAYAQHLIDQAADVLRTQDIGLLTITPPLLERLSRDEKL
                     VSLVNERVKCIRWGGTQMDADSRHLFKTEVFPEVALCGEYGSTMIIGVAGERAGISVDD
                     PCVFDSFSPYVTFTVVDPKSLEPVAYGERGRVLVNHVSKSFLLPSNLERDLATRIPQVN
                     GLVGDSVADIATVAVFDDEAVIEGVY"
     aSDomain        16454..17140
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DWB77_RS21240_AMP-binding.1"
                     /evalue="2.80E-09"
                     /label="DWB77_RS21240_AMP-binding.1"
                     /locus_tag="DWB77_RS21240"
                     /protein_end="316"
                     /protein_start="87"
                     /score="27.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="PDVVGFFESGGTTGAPKRVVLMRDWLDRMVSWSNANLDRHGVPRG
                     GNWLGIIPTGPHVVGTLFRQHAVTHGRHGFTIDLDPRWVKRLIAEGQFGQVDAYAQHLI
                     DQAADVLRTQDIGLLTITPPLLERLSRDEKLVSLVNERVKCIRWGGTQMDADSRHLFKT
                     EVFPEVALCGEYGSTMIIGVAGERAGISVDDPCVFDSFSPYVTFTVVDPKSLEPVAYGE
                     RGRVLVN"
     gene            17295..18689
                     /locus_tag="DWB77_RS21245"
                     /old_locus_tag="DWB77_04287"
     CDS             17295..18689
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031441.1"
                     /locus_tag="DWB77_RS21245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04287"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_120722750.1"
                     /sec_met_domain="Aldedh (E-value: 1.7e-11, bitscore: 42.1,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDLPALGATGAFRTRNRQTITDVAGTALAELSLVPPLYVNRTMA
                     ALRRGSRMSADERADAMIRAAALFATATIDGLTVEEYQYAVSRVGGVPISSVVTATTTV
                     AERVAKAHASVQCARPRGAADTWRDPLTRTGHAVWTRRADVFAVHAAGNHPGTHSIWPE
                     ALALGYRVAVRPSSRDPFTPHRLVGALRSAGFADDQVVLLPTDHAGADAILRGADLGMV
                     YGGEEVTRKYGEAATVLPQGPGRSKILITADVDWREHLDVIVASISGHGGTGCVNTTAV
                     FVEGDPAPLAEAVAARLSTTMPCLPPEDDKAVLPVQPIAAARAIETYLLKKAAGTRAWL
                     GGDGIVGDLGDGSAALLPAVHQLDDPASPQAGVELPFPCVWIAPWTPEAGIDPLKNTLV
                     LNAMTHDTRLIDRLLDEPTISNLYLGDRPTYWMDPSVPHDGYLADFLMRNKGVIRNDIP
                     VANGRD"
     misc_feature    18698..18716
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     gene            18816..20333
                     /locus_tag="DWB77_RS21250"
                     /old_locus_tag="DWB77_04288"
     CDS             18816..20333
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012935.4"
                     /locus_tag="DWB77_RS21250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_04288"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_120722751.1"
                     /transl_table=11
                     /translation="MSHSVEPADVLIVGGGSAGAVLAARLSENPDRRVVLLEAGPDYGP
                     TRYPDALLDANRIADLDHDWGYASRGGRLSPSMVALRGKVMGGSSAVNAGAALRARARD
                     FARWAEDGLDDWSFADVLPYFRALENTPTGEDEFHGRSGPMPVRQLTDAELTPAHRGFI
                     EAAVARGHKRINDFNGAEQDGVGAFAVNVLDGVRQNTALVYLTAEVRARPNLTVHGGVT
                     VDRVLFRGDRATGVVTADGTAHHAHEVILSAGTYASPAILLRSGIGPAGELASLGIETL
                     ADLPVGRHLQDHPFCPAVHALAPGRGEMTPALGALLWTASSEAADGELDLHVVAVHPNG
                     APFMPPGGVIALATALALPEAQGTVRLSGRDPLAQPVIDHNYLGTERDRRRMLEGVRIA
                     RDLARDPALAPSLGGLLMPSELPDGDAELTRVIESSLSIYGHPTSTAPMGAADSPRAVV
                     DSRGAVHGLTALRVVDASIIPYLPSSVTNLTTIMLAERIADLVYNHG"
ORIGIN
        1 ggccgagacc cctactgact tacccctcgc acggtcgtag aacatgcaga ccaacaccag
       61 gccgagatac gcctcggtct tgccgccgcc ggtggggtac cagacgacag tcgccgcctc
      121 ggtcggatcc acgtcgtgtt cgtcgcccca gaggccaggt gtgaagaggt cctcggggtg
      181 ctcccgccag gccagggaac tgagctggct gacgatggcg accagttgga agagccgcca
      241 cccccggctg ggccgctttc gtcgcttgtt gagctccacc atggactcgt tggccagccg
      301 gaacgccgtc aggagacgcc ggtctttgcg aagccaagcg acaccgtcac ggaagcgggc
      361 gacctcgagg gccgcggccc ttcggtctgc ctccttacgc tgggccagct cgggcctgtc
      421 ctggaggtcc tcggtgctcc aggcaggggc ccccaggtac gcctccatct cgtcagcgag
      481 ctcgtcgaga acgggaagcg ggtcggccga gagtgttgcg taactccagc gctcatcggt
      541 tctggccacg gcccgatggg tgtcgtgctg aggaacgggc acactgcgta cggccacgag
      601 cttgccttcg tgccaccggg gctcgacacc gcagttgttc gcgtacgccc cgagctctcc
      661 ggagtagcgg taggcgtcgg caccgaggtc catcacgatg gggaggagat ggtcgccctg
      721 gatctccagc tctgcgcgaa acagggcgtt gtccctggcc tcgtcgcgac gggtacggcc
      781 ggcgttgctg ccccgtccct ggacggtcac gacggggtcg gtggcgaggt tctgcagagt
      841 ggcggtcacg cggagtcgcc cggacgctac gagcctcgac gtgatgacga cgtgcgcggc
      901 gggggacggc accacggggt cgccgccgcc cacctcccgg gccagccact gttcgaaggc
      961 cacatcgtct gccatcgcga caggaggaac cagccgctca cggcggtcgt tcccgacacg
     1021 ccggtcgatc cgagggtctt ggagtgccac cttcacggcg tcctggaagg cgcgccggaa
     1081 ctcggcttcc aaggtctgac gcaggcccgc ctcctgcccc agaacgatgt ccacgggacc
     1141 gacggtcaca gtcagtcgct tgaacagagg ggccagcctg tacggttcct cgcgctcgcc
     1201 agcccactcc agttgttgtg atcgggtcgg aagcgccgcg tagtagaacg atgcccgtgc
     1261 tttgacgctg attgagctgg cattcccagc ctcgaactcg aacccgagac tgtccggggt
     1321 tgtgcggccg taccgcgggg cggctccgcc aggttcgacg gtgtgcgggc cgaggctctc
     1381 catgaagtac cgagcacttg gaggctcacc caggcagacg tccccttggg cctcgccagt
     1441 cgcatcgctg accaccgcgt tgaccaagtg gtccacgagg gcagtctgct gggtgacgct
     1501 cggctcgaac ggagggttgg tcacggcgcc tccccgtcgg atccggcagg ctctgccaag
     1561 accagggaaa gggggcgtgt ccccgcacat gaggggagag atgagagccg aggcggctca
     1621 caaaggcgtg ccagttgagg cagacatgcc gaactggccc gcaggacata gatgtccacg
     1681 ggatctccag gctcgcgagt cagaagccgc tatggcacga cgccatagcc ggacaccttc
     1741 tgctgcttcg agtcacagca gcatcgaacg catctcggcg aagtcgcaag cagataccta
     1801 gagttgatcg aatttgtctg gatccagtct gttggtgcct tgatctgacg ttcaccggtt
     1861 gtggctctgc cgaacgtggc cgcgaagtcg ggcagcgaaa tcagacgggg tcctctgcgg
     1921 cggtgcctac gcgccagccc ttccggcatg attagcgcat gattcccgag gtcgagacag
     1981 aggtcggccg tgacgaactg ggcgatctgc gcactgactt ggacactgac gaggtggtca
     2041 ccgcgtggct gatgctggcg ctggggaagg gccgggagca cgccgggaac gacggctatg
     2101 acgacagtgc atctcagcac tacagctggg acgacaccgt tcagaatcat gcccgcgtct
     2161 cggtgggaga cgtcatagcc ctgtgggaca ggaaggagct catcggcgtc tcggtgatag
     2221 aggccatcga catcgcttct gccgagaaga cgctgtactc ctgtccccag tgcggcaggg
     2281 ccgacatcaa gcggcgtcag cgggagaagc cggcctaccg ctgtggtaag tgcggacatc
     2341 ttttccccac cccgcgccag aagatcaagt cggtgactac ctaccggtct gtgcatggca
     2401 ggagatggat gaacgggcgc ggtctcctct cgggctccga gcttcgggcc ctctgcgatt
     2461 ctccgaagtc gcagctgagt atgcgccctg cgcgatggga gcggctacgg caggcacttc
     2521 tcgacgccac tggtcaggcc agcaccgtca aggacatagc cgcagccgct cgcctggccg
     2581 tagcaggggg tcacagggag tcggtcgtgc ggacgcgcgt tggtcaagag gctttccgag
     2641 cgcggttgct gcgagagcag ggcgaagtct gcgccttcac ggggcccacg ccggctgacg
     2701 ccctggaagc ggctcatctc tacagctacg ccgagagtgg cgagcaccac gagtacggcg
     2761 gactgctcct gcgccgtgac atccacaggc tcttcgacct cggccacatc gcggtggact
     2821 tggcctccgg gaccctcgac gtgatcccga gccttcatgg ctatccgtgc tacgcgcagc
     2881 tgcacggcca gcctgtggcg gtgcagctgc gacctgaaca tcgggtctgg cttgatgcgc
     2941 attggctcgg taagcgcccg cacgcttaac agcgtcggtg gtggaaacgg ccgggacggt
     3001 ctacctaacg ctggtgcgct tcctccgggt ccgggccagc caggcccagc gggtgagggc
     3061 accgacgacg agggagacga ggatggcacc ccagtcgatg acgtggggga ggccagggaa
     3121 gaaggcgaag aacgcgagcg aggcggcggc gccgatggcg aaggcgatga tgccggcgcg
     3181 gcggtgcttc gcttcctgga cggggtcctg ggacgaggtc tcgggggtca tgtgcggctc
     3241 acttggtgat gtggtggcac tggctgactc gccgcacacc gttgacatag aggtgagcgc
     3301 atgccttgcc gtagtggggg agtttctgcg gggcgttgtt gcgcatcggg tcgatcttgc
     3361 actcggtgtg ggtcctgccc ctggaggtgc ggtacgtcct gttgttggtg tccgcgtagg
     3421 tgaagtcgat gcgccagttg cagaagccgc tgttcagagc gccgacgaag ccgcagtcca
     3481 cgccggcgtt ctgataggtg atgctcttgc cgtcgccgcg gatgatgtgg gtgaacgcgc
     3541 agcctgtcgg gatcttcatg gtgacacctc cgacttggta gtcgaaggtg gcaacgggag
     3601 tggtgccgat ggcggtggca tgtgcggctg atggaggtaa gagggcaagt gccgccatcg
     3661 taagaagagt tgcgatggtt cgggctgtga agcgcatggc catgagcggc tcccttttcg
     3721 gtggagtgtg tgccgagatc gggaactcca ggcgctgact caaggttctg cgtcgaagaa
     3781 cagaccacta cgatgagtga tcagcagatt ggtgggctga ccagctgcgt tcatctgctc
     3841 cggcgccgac tccgtgcgtg agcggacacg gcggcacacg ctggacgcga cgtcacaggt
     3901 cgcagcccga cgagtccttt gaccaggcaa gacaggatcc ggtgtgccac cgcggcacca
     3961 tccgtcacga tcttgcaggc cctcgtaatg cgtaggtctc gggttcgaat cccgaaggcg
     4021 gctctgtgga agccccagga ctcactcgcc gtgacctggg gcttttgctt gtgcgtttgc
     4081 tggaggtgcg ggctgcgcgg tgcgccccct gccgtctgcg ggccgtggtc ttggccagcg
     4141 ggctgggggc gtcgagggtg gggctcaggg ggtcaggatt tcgcactcct tgatgaccag
     4201 gaccgttccg tcctcgctga agacccggca ctctcccttg acggtgacgg ggacgcccag
     4261 ggggacgctg cgcacgatgc ggaacgactc cttgatccgg tggtcgaacg gcagcacgaa
     4321 gatggcgagg tgggggcctc cggggacgtc tgacacgtcc accaccggcg taccgtactg
     4381 gctttcgccc gtgcggatgg agactccttc aagggtgagg tacttcccgt agtaggcgcg
     4441 ctcggcggcg gcgcggtccg cggtgaattc gtcgtggagg tctcggattt tcatggggtg
     4501 ccgccttctc tggggtcggg tgggcctggt gggcctggtg gttctggtgg tccggacagc
     4561 caaaacggcc cgccgacaag atgacgggcc gtgatgggga tcgaggatcg aaggcagtcg
     4621 tgaagactcg acgtattcac gagtggtcga gggtcagccg accggcgtct cgctgttcgc
     4681 gaggagcctg cggtattcct tggcgtccag ggcgagggtc tcgtccgacg tctcgaagat
     4741 catgccgtag acggcgtgga aaccctggta gtcgagctgg cagaacgcca gcgtctgagt
     4801 gaccggggcg aggtactcgt cgaggggccg acgggcggcg ccgtccgtgg cgtaggtctc
     4861 cagggtgctg ccgaccgtca cggcgagcca ggccttcttg ccgctcagcg cggaggggga
     4921 accgtcgaag gtgaaggcga acccgtgaat cagtaccgcg tcgaaccacg tcttgagcat
     4981 cgaggtcacg ttgtaccagt agaccgggaa ctggaggacg atggtgtcgt gctcgcgcag
     5041 cagctggtgc tcgcgttcga cgtcgatctt gccgtcgggg tacgtcgcgt agaggtcgtg
     5101 gacggtgacg ttgtccaagt ccttgatctc ggccagccgg ttggcgttgg cacgggattc
     5161 cgtgaggttc gggtgggcga caatgacgag ggtgcgattg gtggtcactg gcttttccat
     5221 ctctcgtgta ggacgcgaac ccgtgtgcgt ccctggctgt ccatggtggc gagcaggtcc
     5281 gccgtggccg cggtcatgcg ctcttctcga gccctttgaa gggtggtcgc ttccggaacg
     5341 agcggctgct cgtcttagta aaagcggtgg ttggaccgag cggtgtttgt cacgcgatat
     5401 tgacggactc gttccatcgg aggccgtccg cgtgggggat attcacgctc aacccccacg
     5461 ctctgccccg gagttgcctc cgaggtcact gcctcagcgc tcggcgatct gcccgatggt
     5521 gtcgagttcg acgaccgcct cgtcgggcag gcgcagctcg gccgcggcga tgttctcccg
     5581 cagatgggcc acgctggagg tgcccgggat cagcaccatc gacggtgagc gctggagcag
     5641 ccaggcgagc gccacctgct gttcggtggc gcccaggcgg tgggcgacgt cgcgcaggat
     5701 ccgtgaccgc agcgggctga atccgccgcc gagggggaag aacgcggcgt aggcgatgcc
     5761 ttcctcggcg cagcggtcga cgaggtcgtc gtcggcgcgg tcggccaggt tgtactggtt
     5821 ctgcacggtg accacggggg cgatggcctg ggcctgggtg agttgggatt cggtgatccc
     5881 gctgaggccg aggtgacgga tcaggccctg ctcccgcagg tcggccaagg cgccgaacgg
     5941 ctcggcgaca gaggatgcgt caccgccgaa ggaggccgta cgcaggttga ccacgtccag
     6001 ggtttccagg ccgaggtgct ggaggttctc gtggacctgg gccttgaggt cggcggggtc
     6061 cagggaggtg atccagccgc cgccggcgct gcggcggaca ccgaccttgg tgacgatgtg
     6121 caggtcggcc gggtaggggt gcagggcctc cctgatcagc tcgttgacga cgaccggtcc
     6181 gtagaagtcg ctggtgtcga tgtgggtgac gccgagctcg accgccgcgc gcagcacgcc
     6241 gatcgcctcg gcgcggtcct tgggcggtcc gtagacaccg ggaccggtca gctgcatcgc
     6301 gccatatccc atgcggctga tgcgcaggtc gtcggcgagg gtcaacgtct gtagggggct
     6361 ggtcatcaga agcctctcgg gtctgttcgc ggcgtcgttg cggatcgccc ggcgcgcgtc
     6421 caggggtaag tttcgatggg tgcggcggtg gtggcagggt acggccgggc ggccgggcac
     6481 gcgcacctca acccagccaa ctcgtggcag gcgagcggga cttgacagcc cgggtgccgt
     6541 gaggtgagcc ttcgaccccg ggcccgttgc gaagtccggc gccgacgtct gcgcggcgcc
     6601 cgcaccactt cgtacgccgc tacgtacagg cctccgcaac cgcccggcgc ccaccggacc
     6661 cgcccgaccg gcgcccgcgg tggcccccta aaagccccct aaaagggggc tccgtcacgg
     6721 ccgcgccccg acctcctcaa ccggcgtgcg cagagcggcg gatcacgcca cggacgccgc
     6781 cgggttggtt cgggcggccg ccccgacgat gtcgccgtgc ggggaagtcc gcgccaccgt
     6841 cgcgaagttg aaggccttgt cgcgaacggt gatcgtccac gaaaggccgg acctctcgcc
     6901 cgccgtgatg cccagcacga tggtcggcat gtgccactcg tacctcatga gcgtgccgtg
     6961 gtccgcctgg acgtccgtgc cgtcgtgcgc cgatacgttg ccgtagttgt tgacgcagaa
     7021 gacattgggc gtggcgatca gattcccgat cctggcccgg ccggcttcga tgaactcgtc
     7081 ccgcagctcg atgcgtgaca gcacgtccat gtgccgctgc tcctcggcgc ggtagtagtc
     7141 acggatctgg attcccgtgc tctgcgtgac cacgccgcgc ggcaccgtca ggaactggag
     7201 cgagttgccg aggggcagtt tgggcgagta gaggctgttc ttgaggatga gcatgttttc
     7261 gctgtcacgc tcgacgaggt ccccccgcat ccgctccaga aaggagccga tcttgacggg
     7321 cgagccggag ttttcggtga acgagacggg gagttccttg ctcgcgccgg agggcgccgc
     7381 ctccacgggc ggcacgaagt ccgccagctc atcggagcgg atccccagct ccgcgaggcc
     7441 ctgggcgatc tggaatccgt cctgcttggt cttcagggtc ttcatcagcg cctggtgaag
     7501 gtggaagcac ttgtatccgt cttgcagcgg aaacggcacg caagtgaaga tgccctggag
     7561 gtgcgggtcg gagcgatagg tgacggaagc gaccaggaag ctgtcgtagt agctttcgta
     7621 cttttccgca aggagcgcct ggaacgacgc gagggggaaa tcctcaggac tgtcgaaggt
     7681 cagctccacc aggtgacact tggagaaaag cgggttcccc cggaagaagt gcttcatggc
     7741 ctcctcgaac tcggtgagat cgaagatcct gtcgaccttg tacgtcgaga gcgccggaaa
     7801 gaactgcgac gcgtcgatga acgggaacgt ggtcatggag agccgaagga ctttgtcggc
     7861 gatggagatg ggcatgggcg tgacctccgt taatgggtgg gtgccggggc cgacgagcga
     7921 cgccggcgat gtgccgccag gacgcgccgc atggtgctcg gggtgcacag ggtcgtcggc
     7981 ggttccagca agtactggac tttcaggaac ttctcggcca cgaccatgtc cgtttccgcc
     8041 gcggcgagca ccttgtccat gtaggagttg atgagccgca cgggaagggg tctcgggcct
     8101 tcgatctgag gcagggccag gtcactgccg gtcgccatcc gccaggcgac gccgatgggt
     8161 ttggcggcct tgcggaagaa acgttgcgcg acctgatcca ggtcaccgct gagcgagtca
     8221 cgcagcgcca tggcctggag cgaggccacc gtcatcccct gggcgtagat ggggttgaag
     8281 ctggatatcg catcgcccac caccaccagc ctgcgcggga accgggtcag cttctcgtag
     8341 cggcggcgca cgctcgccgg gaaccggtgc gcggagatct cgctgagcgg ctcggcgtcg
     8401 cggatcgccg cgaagacgtg gtcggggacc aggggcctgg cgaactctat ccacccggcc
     8461 gggtcggtcg gcgggtggtg atcgcggtag ccgatcagcg tcaggaccca gcggccgtcc
     8521 tcttcctcca ggaactccgc gcccttgggg ctgcccggcg cgtgcccgat gatcacgacc
     8581 ttctcgcggc ccatcgagcc gggggccggc cgcaggtacc ggctggtgta catgatgtcg
     8641 acgtcgatgc gctcctcggc cggcggctcg taccccatct cgaccagcca cttggtggtc
     8701 cgtccggacc ggccggtcgc gtccaccacc agatcggcgg ggatcacgtc ctccgagccg
     8761 ctgccctcgt acctgacgcc cacgccggtg accgtgccgt tgtccgaggt ggtcctcagg
     8821 ccggtgacct ggcactggtc gatcaccttg atccgcgaga gcgccccgat ccgggcgcgg
     8881 agccggctct ccagatgcgg ccggctcggc tggtaggtgc gggacaggtc ggcgtactcg
     8941 ccgtccatgc acaacaggtg gccgcccaag cgcatccgca gttcggcggg tccgtcgatg
     9001 acgggcgcgc caccggcgac gaagtcgtcg aggatcccgg ggaacagctc ctcgaagatc
     9061 ttcgcgccct tggaaagcag gccgtgggcg tggcggccct gcggcacacc tcgccgctgc
     9121 gtccgctgcc cgtccggcag ctggtcgcgc tctaccaccg ttacccggtc gaatgcctcg
     9181 gagagcaccc gagcggcaag cagacccgaa atgctcgcgc ccagcaccac cgcatgttca
     9241 ccaatacgct tcacaggaat tccttctggt cgggcaagcg tcatgtgtgt gttggcaagc
     9301 gccttgtgtg gggtgtgtca gcaatatgtg ggtgatcgcg gccgatgctc cggcgatggt
     9361 ttcccgaatt cttcgatacg gactcatcga ggtccgggcc ggggaggtgt tcggtgcgca
     9421 tcgcgaaggt aggtgctcga cgggttcggc cacggaacgt gccgcggtat tggctggttc
     9481 gttccatcga gcgcggctgg agtggccgaa attcacgggg gatgcgtggg tccgcccgca
     9541 cgggtggcgg gcctgcggca cgtgaccggg caggcggcgg cccgaagggg cgcgctgccg
     9601 acgggagttg agggcgtccc tcgcccagga gcggcacaag agagaggagt gcaggcccgg
     9661 ccggtagacg gggcccgccc tccgctgtcc agggccccga tcggggggtc gggaccccgg
     9721 cagagccgcg tccgccatgg agcagatcct ccagaccatg gagtagatcc ctcaggcggt
     9781 gatacccgct ggaacttttc ggccagacag tggtgatcgg gctcctgaac cggccgaagc
     9841 gtgagcaaag tcctcgcaca acccgccggg catcgaggcg agttcaacag gaatctcatg
     9901 aaccaccgca tgacgacgct tctttggcat cgtcgtgatg gtcgagtctg cccttgtgca
     9961 cgcggttgtc ccgcattact tcggcactac aggagatcca atggccgaca tcaccggcat
    10021 cgctgaaacc gctcaatccg ctgaatccgc tgctacgttc gcggagtcac gcggcgaatc
    10081 ggaactgcga gcgagcaacc gtgcgatcgt ggagcagtac atgaataccc gggggcagga
    10141 tcgcctgcgc cggcaccttc tgttcaccga agacggcacc ggtggtctct ggacgaccga
    10201 gaccgggcag ccgatcgtca tcaccggccg ggaccgactg ggtgaccacg gtcaatggtc
    10261 gctcaagtgc ttccccgact gggtctggac gaacatcgag gtcttcgaga cgcaggaccc
    10321 caaccatttc tgggtcgaat gcgacgggga ggggacgatc cgtttccccg actaccccga
    10381 cggccactac cgcaaccact tcctgcattc cttcctgttc gagaacggga agatcaagcg
    10441 ccagcgcgag ttcatgaacc cctgcgaaca gttcagggct ctgggcatta ccgtcccgca
    10501 ggtcaagcgg gccgacatac cgacctgaac gccgttcgcc gggcgtcttc tgatcaatca
    10561 atggggaagg tcgtgatggg aaacatcctc gtcgacatcg acagggccaa agcgcgtcac
    10621 cagcccgaat ggaacaatcc ggcacaggtc gaactcgtac gagcgatcct gtcgtccgtc
    10681 acaccgctgg tgaccgccgc gcaggtggag gacctccgct cccacctcgc ccgcgtcgcc
    10741 accggcgaga tgcaggtgct gaaggccggg gattgcgcgg aggacccggc cgagtgcacc
    10801 gccggccaca ttcggagcaa gaccgagctc atcggcctgc tcgcccagaa cctggagacc
    10861 gccaccggca agcggacgct gcgggtcggg cgcatcgcgg ggcagttctc caagccccgc
    10921 tccagccggt tcgaaaagct cggcgatgcc gaactgccgt ccttcttcgg gcacatgatc
    10981 aacgggccgg agcccaccca cgagagccgc cgtcccgacc ccctgcgcat gctcacgggc
    11041 tatatggccg ccagggagat catgacgcag ctcggctggg tcgggtccgt gcctcgcacc
    11101 gacgggtccg ccgtctggac cagccatgaa gcgctgctcc tggactacga gatatcgatg
    11161 ctccgcgagc tcgacggggg tcggcgcctg ctgagctcca cccactggcc gtggatcggc
    11221 gagcggaccc ggcaactcga cgggccgcac gtcgccctgc tcgcccaggt gatcaacccg
    11281 gtggcctgca aggtcggccc gtccatgacc cccggcgaga tcgccgagct gtgcgaccgg
    11341 ttggacccgg agcgggagcc gggccggctg tcgctcatcg tgcgcatggg cgccgacctc
    11401 gtcgccgacc ggctgccccg gctcgtggag gccgtgaagt cggccgggca cccggtggtc
    11461 tggctcaccg acccgatgca cggcaacacc gagagcgccg ccgacggcac caaataccgg
    11521 ctcgtgggca acgtcgcccg ggaagtccgc ggcttccggc gggtcctcga cctggccggg
    11581 gttccggccg ggggctccat ctggaggcga cccccgacga cgtgaccgag tgcgtgcttg
    11641 acacggccga gctggggtcg ggccccgtca ccagcctgtg tgacccgcga ctcaacaccg
    11701 gccaggccat cgaagtggtc tcggcgtggt ccgggtactg agattcctag agagggagcc
    11761 ttttgatgac gggaatacca ccgatcgcgc cctacagtct gccgccgagt catgcgctgc
    11821 cggagaactc cgtgcgctgg accgtccacc cggatcgggc ggtgctcctc atccacgaca
    11881 tgcagagcta cttcctcaat ccctttgagg acggcatgcg cagcaccttg gtgcacaccg
    11941 tcgccgacct caagaagcgc tgcgcggcgc tgggagtgcc ggtggcctac accgctcagc
    12001 ccggcagcat gacggacgag gaacgcgggc tcctcaagga cttctggggc cccggcatgc
    12061 gcaccgacga ggccgaacgc gcgatcgtgc ccgaactcga acccgacccg gaggactggc
    12121 tgagcacgaa gtggcgctac agcgcgttct tcaagtcgga gctgctccag cgcatgcgcg
    12181 ctctccagcg tgaccagctg atcgtttgcg gcgtctacgc acacatcggt gtgctgtcga
    12241 cggctctgga cgcgttctcc aacgacgtcc agcccttcct ggtcgccgac gcgctcggtg
    12301 acttctccgc ggcccaccac aggctgaccc tcgcctacgc ggcacggtcc tgcgccatgg
    12361 tggtcaggtc cgaggacgtg ctcgcatgag cgcgctgctg gagcacgtcc tggcgctgga
    12421 agtgcccgcc ttcgcgatca tccaccgccc cgagagcggc tgcgccggca cgctcgacgt
    12481 cctgacgggc ccggtgaccg agtacaagtc gctggacgac atcccgttgg ccgacgactc
    12541 cgtgccgggc cccgcactcg acacgctggt gctcgtcccc taccggcagc tggccgaccg
    12601 cggcttcgcg gcgcgggacg acgccacgcc cctgctggcg atgagcctca ccgctcgcga
    12661 caccgtgccg gtcgccgaag cgctggcccg cttcccacag gcccctacgg agctggccga
    12721 cgggcacttc gacgtggacg acgccgcgta cgcgcagatg gtgcgccaga tcgtcaccga
    12781 cgagatcggc accggcgagg gcgccaactt cgtgatgaag cgctcgttcg tcgcggacat
    12841 cggcgactac tccctgacca gcgccctgtc gttcttccgg cggctgttgg agcgcgagga
    12901 gaaggcctac tggaccttca tcatccacac cggccgcaac accctcgtcg gggcgacacc
    12961 ggagcgccac atctcgctcg ccgagggcgc ggccgtgatg aacccgatca gcggcaccta
    13021 ccggtatccg tccggcggcc ccaccttgca gggcgtcatg gagttcctcg ccgacaccaa
    13081 ggagaccgac gagctctaca tggtgctcga cgaggaactg aagatgatgg cccggctgtg
    13141 cgacgacggg gggcgcgtcc acgggccgta cctgaaggaa atggcgcgcc tcgcgcacac
    13201 cgagtacctg atcgagggca agaccaaccg cgatgtgcgt gaggttctgc acgagacgat
    13261 gttcgccccc acggtcaccg ggagcccgct ggagagcgcc gccaaggtca tctggcgcca
    13321 cgagccgaac ggacgcggct actacagcgg ggtcgccgcg ctgatcggac gggacgcggc
    13381 gggacggcag accctcgact cggcgatctt gatccggacg gccgacatcg atcccggcgg
    13441 ccggatgaac atttccgtgg gggccaccct ggtgcgccac tccgacccga tgaccgaggc
    13501 cgccgagacc cgggccaagc tggcgaccct gctcaacgcg ctcaagtccg acccgtgttc
    13561 cggctacgcg gccgacccgg aggtccgtgc cgcactggac cgccgcaacg acaggatcgc
    13621 ggggttctgg ctccgggaca ggtgcgagcg ccggccggcc gggactccgc tggacggcgc
    13681 gacggccctg gtcgtggacg cggaggacac cttcaccgcc atgctcgacc agcagttgcg
    13741 gtcattgggg ctgtgcgtgg aggtccgccg cttcgacgag ccgtacgacg tggccgccta
    13801 cgacctcacg gtcttcggcc ccggcccggg agatccgcgg atggcctccc accccaagat
    13861 cgccaagctg cggcagtcgg tcgacaccgc gctggcccgt caccggccga tgctggccgt
    13921 gtgcctgagc caccaggtac tcagcatgaa gctcggcttc gacctgcacc gccgcgaggt
    13981 acccaaccag ggcgtccagc gcgagatcga cctgttcgga ctgcgtgaac gcgtgggctt
    14041 ctacaacacg ttcgccgcgc acagcgcggt cggcagacga accgtcgaag ggatcggtgt
    14101 ggtcgaggtg agccgggacg agcagagcgg cgaggtgaac gcgctgcgcg ggccgggctt
    14161 cgcatcggtt cagttccacg ccgagtcggt gctcaccgtc gacggcccgc gcatcatccg
    14221 cgaggcgata cagggggtac tcggccgatg agagtggatg tcgtctggtg ggacctggcc
    14281 aggtcccacc agaccatcga atccctggag agggatctgc gggactccgt cgagccctgg
    14341 cacgaggtca ggggactgcg cctgaagctg tggatcgccg accgtgaacg cggccgctgg
    14401 ggcgcggtca tgtggtggga ctccgacgtc ccggccgatc agccgctgcc ccccaaccgg
    14461 gcggccgagc tcatcgggta cgcccccgac caccgcagcg ccttcgacgt cgccgcggtc
    14521 gccgagggaa tcgacgcgct cggcctcgcc ttctccgccg aaccctcaac aacctcggca
    14581 cacgtcacgg agctccgata atgcaccagt acatggtcgt agacgctttc gcccgcgaac
    14641 cgctgcgggg caacccggtc gccgtcttct tcgacagcga ggacctgacc ggcgagacga
    14701 tgcagcgcat cgcgcaggag atgaacctct ccgaggtcac cttcgtgctg ccggccgaac
    14761 agggcggcga cgcacggatc aggatcttca ccccggtgaa cgaactgccc ttcgccgggc
    14821 acccgatgct cggcacggcc cacgcgctcg gccggacctg gaaacgcgac aggctgcggc
    14881 tggagaccgc gatgggcgtc atcccgttcg agctcagtac ccgcgacggc gccgcatggg
    14941 tccggatgcg gcagcccgtt cccagctcga agccctacga cctcggcgcc gacctgctgg
    15001 ccgcactcgg ggtcgagacg tcgacggccc cggtcgagat ctaccacaac gggccgcgcc
    15061 acgtgttcgt gggattgagc gacgtggggg cgctgtccgc gctccacccg gaccaccgcg
    15121 ccctctcgcg cttccccgac atggccgcca actgcttcgc cagggcgggc gacggctggc
    15181 agatgcggat gttctccccc gcctacggcg tggtcgagga cgcggcgacc ggctccgccg
    15241 ccgggcccct cgcgatccac ctggcccgcc acgggttcgc cgagtacggg caggagatcc
    15301 agatcaccca gggcgtggag atgggacgct cctcggtcat gagggcgacc gccgagggga
    15361 ccggcgagtc gatccactcg gtccacgtcg gcgggcacgc cgccgtggtc gctgagggga
    15421 ggctccatgt ctgagcgcga actcctcgtc tccgccagtg aattcgagtc gctcagcggg
    15481 aaggtcgacc tgcccttccc cgagtacgac cagccgcctt cggaacctct cccgctggtg
    15541 cggagctggc tcgaccgggc acgggagagc ggagtccgcg agccggccgc actcgcgctg
    15601 gccaccgccg actcccgagg gcgcgcctcc aaccggacga tcgccatcac cgaagtcacc
    15661 gacgccggcc tggtgttcac cagccacagc tgtagccaga agggacgcga actcgccgcc
    15721 accgggtggg cgtcgggctt gctgtactgg cgggagaccg gccagcagat catcatctcc
    15781 ggtcccgtgg tgctcctgcc cgacgccgag tcggacgccc tgtggtccgc ccggcccact
    15841 ccgctgcacg ccatgtcgac ggtcaccgag cagagcgagc cgctggagga cgtcgaggcc
    15901 ctgcgcgtgc gggcacgccg cctggaacgg accggagcgc cccagccccg gccggagttc
    15961 ttcgtcggct accggctgga gcccgccgtc gtcgaattct ggtccgcgag ctcggatcgg
    16021 ctgcaccgca ggctgcgcta tgaccgcggc ccgctccagt ggcgtacgag ccgactgcaa
    16081 ccgtagccgc cgcacctacg gccaactccc gtggtgcgca acccggttga ccgccccggc
    16141 ggttgggccg tagtgcccgg acccacccga cccttttcct gaggaagaga ccatgcctct
    16201 cagcgcagaa cagatcctgg atcttccgtt cgacgtccag cccgatccgg acgactacct
    16261 ccgcgccgcc atggagtggc acttcaatcc cgagaccggc tgtgcgttct ggctggaccg
    16321 ggccgccacg ctcggcttcg atccgcgggc cgacgtcaag acgtacgagg acctccggct
    16381 cttccccaac ctggcggcgg agcttcgcga cgtccgtggc gaggacctgg tccccagggg
    16441 ctacggcacc aggcccgacg tggtcgggtt cttcgaaagc ggcggcacca ccggcgcccc
    16501 gaagcgggtc gttctgatgc gggactggct cgaccgcatg gtgagctgga gcaacgcgaa
    16561 cctggaccgc cacggcgtgc cgcgcggcgg gaactggctc ggcatcatcc cgaccgggcc
    16621 gcacgtcgtg ggcaccctgt tccggcagca cgccgtgacc cacggtcgcc acggcttcac
    16681 gatcgacctc gatccccgct gggtgaagcg gctcatagcc gagggccagt tcgggcaggt
    16741 cgacgcgtac gcccagcacc tcatcgacca ggccgccgac gtcctgcgga cccaggacat
    16801 cggtctgctc accatcaccc cgccgctcct tgaacggctg tccagggacg agaagttggt
    16861 ctccctggtg aacgagcggg tcaagtgcat cagatggggc ggcacccaga tggacgccga
    16921 ctcccggcac ctgttcaaga ccgaagtctt ccccgaggtc gcgctgtgcg gcgagtacgg
    16981 aagcacgatg atcatcgggg tcgctggcga gcgggccggg atctccgtcg acgatccctg
    17041 tgtcttcgac tcgttctccc cctacgtcac cttcacggtc gtcgatccga agagccttga
    17101 gccggtggcc tacggagagc ggggccgggt gctggtcaac cacgtcagca agtccttcct
    17161 gctgcccagc aacctggaac gcgaccttgc cacgcgaatc ccccaggtga acggcctggt
    17221 cggggactcg gtcgccgaca tcgccaccgt cgcggtcttc gacgacgagg ccgtcatcga
    17281 gggggtctac taaaatgatc gacctgcccg cgctcggtgc aacgggcgcc ttccgcacca
    17341 ggaacagaca gacgatcacc gacgtggcgg gcaccgccct cgccgaactg agcctcgtac
    17401 cgccgctcta cgtcaaccgc accatggcgg cgctgcgccg gggcagccgc atgtcggccg
    17461 acgaacgggc cgacgcgatg atccgtgcgg ccgcgctctt cgcgaccgcg accatcgacg
    17521 gcctgaccgt cgaggagtac cagtacgccg tcagccgcgt cggcggagtc ccgatctcct
    17581 ccgtcgtcac ggcgaccacg acggtcgccg agcgggtcgc gaaggcgcat gcgagcgtcc
    17641 agtgcgcgcg gccgcgcggc gcggccgaca cctggcgcga tccgctgacc cggaccgggc
    17701 acgcggtgtg gacgaggcgc gcggacgtgt tcgccgtgca cgccgcgggc aaccaccccg
    17761 gcacccacag catctggccc gaggcactgg cgctgggcta ccgcgtcgcg gtccgcccgt
    17821 ccagccgcga tcccttcacc ccgcaccgac tcgtcggcgc actgcggagc gcgggattcg
    17881 ccgacgacca ggtggtgctc ctgcccaccg accacgccgg cgccgacgcc attctgcgcg
    17941 gcgccgacct ggggatggtc tacggcggcg aggaggtgac tcgcaagtac ggcgaggccg
    18001 ccaccgtgct gccgcagggg ccgggccggt cgaagatcct catcacggcc gatgtggact
    18061 ggcgcgagca cctggacgtg atcgtcgcct ccatcagcgg ccacggcggg accggatgcg
    18121 tgaacacgac agccgtcttc gtggagggcg acccggcccc gctcgccgag gccgtcgcgg
    18181 cacggttgtc caccacgatg ccctgtctgc cgcccgagga cgacaaggcc gtactcccgg
    18241 tacagccgat cgcggccgcc agggcgatcg aaacgtacct gctcaagaag gcggcgggca
    18301 cccgggcctg gctcggcggc gacggcatcg tgggcgacct cggggacggc agcgccgcgc
    18361 tgctgcccgc cgtccaccaa ctcgacgatc cggcgtcgcc ccaggcgggc gtggaactgc
    18421 cgttcccctg cgtgtggatc gcgccgtgga cgcccgaggc cggcatcgac ccgctgaaga
    18481 acacgctcgt gctcaacgcg atgacccacg acacccggct gatcgaccgg ctgctcgacg
    18541 agccgaccat cagcaacctg tacctgggag accggcccac ctactggatg gatccctcgg
    18601 taccgcacga cggctacctc gccgacttcc tcatgcgcaa caagggcgtc atccgcaacg
    18661 acatcccggt cgccaacggc cgcgactgac gggtcattcc ggccacgctc acctcaacac
    18721 tcacagctgt gccgcagtgc gctccgctgg cgcccgctgc ggcacaacca ccgggacgct
    18781 cccaccccct cccgcgcgat cgaaagggtc ctaccttgtc ccactccgtc gaaccggccg
    18841 acgtcctgat cgtcggcggt gggtcggccg gcgcggtgct cgcggcccgc ctgagcgaga
    18901 accccgaccg gcgcgtcgtg ctgctggagg ccgggccgga ctacggcccc acccggtacc
    18961 ccgacgcgct gctcgacgcc aaccgcatcg ccgacctcga tcacgactgg ggatacgcct
    19021 cgcggggcgg gcggctgagc ccctccatgg tcgccctgcg cggcaaggtg atgggcggga
    19081 gttccgccgt caacgccggc gccgcgctcc gtgcccgcgc ccgcgacttc gcccgctggg
    19141 ccgaggacgg gctcgacgac tggagcttcg ccgacgtcct gccgtacttc cgcgccttgg
    19201 agaacacccc caccggcgag gacgagttcc acgggcggag cgggccgatg cccgtgcgcc
    19261 agctgaccga cgccgagctg acccccgcac atcgcggctt catcgaggcc gcggtcgccc
    19321 gcggccacaa gcggatcaac gacttcaacg gtgccgagca ggacggcgtc ggagccttcg
    19381 cggtcaatgt gctcgacggg gtccggcaga acaccgcgct ggtctacctc accgccgagg
    19441 tgcgcgcccg cccgaacctc acggtgcacg gtggcgtcac cgtcgaccgg gtcctgttcc
    19501 gcggtgaccg tgcgaccgga gtggtcaccg ccgacgggac cgcgcaccac gcccacgaag
    19561 tgatcctctc cgccgggacc tacgcgagcc cggcgatcct gctgcgctcc ggcatcggcc
    19621 ccgccggcga actggcgtcg ctcggcatcg agaccctcgc cgacctgccc gtcggacgac
    19681 acctgcaaga ccatccgttc tgccccgcgg tccatgcgct cgccccgggg cgaggagaga
    19741 tgacgccggc cctcggcgca ctcctgtgga ccgcctccag cgaggccgcg gacggcgaac
    19801 tcgacctgca cgtcgtcgcc gtgcatccca acggggcgcc gttcatgccc ccgggcggcg
    19861 tcatagccct ggccacggcc ctcgcacttc ccgaggcgca gggcacggtg cgcctctcgg
    19921 gccgcgatcc gctcgcccag cccgtgatcg accacaacta cctcggaacc gagcgcgacc
    19981 gccgacgcat gctcgaaggc gtacgcatcg cccgtgatct ggcccgcgac ccggcgctcg
    20041 ccccgtcact cggcgggctt ttgatgccga gcgaactgcc cgacggcgat gcggaattga
    20101 cccgggtgat cgaatccagt ctctccatct acggtcaccc cacctccacc gcccccatgg
    20161 gcgccgccga ctcgccccgg gccgtcgtgg actcccgtgg cgccgtgcac ggactcaccg
    20221 ccctgcgtgt cgtggacgcc tcgatcattc cgtacctgcc ctcaagcgtc accaacctga
    20281 cgacgatcat gctcgccgag cgcatcgccg accttgtcta caaccacgga taaccacggg
    20341 ctgtcgagag gtcggccgct cacttttctt attcgtgaac tcctcaattc cttcacgaat
    20401 aggtgagact tcaccgccgt ttccctggct gaacttgccg gagttcagcc gggggaagtc
    20461 cggcttgggc cgcggcgggc gccgcatccg atggcgacat ttcgcaccat gcggagactt
    20521 tggactca
//
