LOCUS       NZ_CP032698            22781 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces hundungensis strain BH38 chromosome, complete genome.
ACCESSION   NZ_CP032698
VERSION     NZ_CP032698.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces hundungensis
  ORGANISM  Streptomyces hundungensis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Relationship between Morphology and Antimicrobial Activity in
            Streptomyces
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8393044)
  AUTHORS   Kang,H.J. and Kim,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-OCT-2018) Microbiology and Molecular biology, Chungnam
            National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Korea,
            Republic of
COMMENT     ##Assembly-Data-START##
            Assembly Method                   :: RS HGAP Assembly v. v3.0
            Sequencing Technology             :: PacBio RSII
            Assembly Date                     :: 2018-07-09
            Expected Final Version            :: Yes
            Genome Coverage                   :: 130.0x
            Genome Representation             :: Full
            ##Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003627815.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:42:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,472
            CDSs (total)                      :: 7,378
            Genes (coding)                    :: 7,187
            CDSs (with protein)               :: 7,187
            Genes (RNA)                       :: 94
            rRNAs                             :: 8, 8, 8 (5S, 16S, 23S)
            complete rRNAs                    :: 8, 8, 8 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 191
            CDSs (without protein)            :: 191
            Pseudo Genes (ambiguous residues) :: 0 of 191
            Pseudo Genes (frameshifted)       :: 103 of 191
            Pseudo Genes (incomplete)         :: 121 of 191
            Pseudo Genes (internal stop)      :: 14 of 191
            Pseudo Genes (multiple problems)  :: 42 of 191
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:58:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 305424
            Orig. end                         :: 328205
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032698.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22781
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="2"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22781
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22781
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12781](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12781
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    848..863
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.28"
                     /tool="antismash"
     gene            complement(1496..3667)
                     /locus_tag="DWB77_RS01505"
                     /old_locus_tag="DWB77_00310"
     CDS             complement(1496..3667)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019982395.1"
                     /locus_tag="DWB77_RS01505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00310"
                     /product="hypothetical protein"
                     /protein_id="WP_120719533.1"
                     /transl_table=11
                     /translation="MVHRLEPLVIRHTHRVPRLTGAAGQGAVAARQFDAALMSVGFKLS
                     AELFAHLSGFSEEAVVDTAVRTLHTVREMVGDHVQHNAYFIDFPANVPDTLDFWMECIA
                     DALADATTRTSTLEQLSTGVVDLLTLPSYGNPRHTYAEMLAHHDELIAAAGDRITVLHL
                     GASLGDELTALYLALAGRATPLGEDGLRDLQDLAGHCADGPQPQEIPVRENRAVVNQAR
                     LMTGAAPLLDTVTDVLRLACALVGGDVTLREPTRLRSLPRSMRRALLAGLDAVIAAGPA
                     KLADVHADREMWKRLGERLHPHEYPQWPHAADVFAVARGEKTARSLDSRVEELLARGDT
                     TAAVGLLKVAPGKLLRALDQLLRDSFTQDERDAVVAAAERSVADVSGRVLLSVRQHLHN
                     RERETSERRVFINRLGRAWVTDDTRRPVFAPERERLITVLDTELRRRLAAREHLLIDPD
                     VLDVALPLSGKATASGLGVLPRGSVSRVDGELLRFFVHWKQSERTTDFDLSAALLNADY
                     STASWLSYTNLRGVEGEHSGDITDAPDGASEFINLRLGAVRAHCIVPQINIFSGEGFEE
                     VEESFFGFMLREGEQKGLPFEARTVRMKSELRGPGRVALPLVFLRGSDGTWRAKWLHLY
                     LKGAPSANRVEENRVTVATLLRGIVEREQLTVRYLTELMTGSATTVTSWDGKSVPAGPV
                     TYIGLERPDGLHPQSRIITPENLGDLIPA"
     misc_feature    3706..3720
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.0"
                     /tool="antismash"
     gene            3881..5080
                     /locus_tag="DWB77_RS01510"
                     /old_locus_tag="DWB77_00311"
     CDS             3881..5080
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS01510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_00311"
                     /product="hypothetical protein"
                     /protein_id="WP_120719534.1"
                     /transl_table=11
                     /translation="MALQISYRGGRLGEDLDITVYWFPREPDRPAHYVSDILGAWRVSI
                     PRDVDASGTPQEIVSWNDAAASFVQRIAAEDRELAKAERAIGRWGLLVTRRRAQLRYDD
                     ARTSFLEAVRSAAAAYQPVRDVIEARLAEREAHAREAARRAYQGKERQWRDEAARFREW
                     ERRQEVADRPLPGGLSPREMAASGDAPVNWPAEVRSLVGDTSSWWTSVRASERNRRANA
                     QAVRKVTEAINGVAAALEETGRPGISTIRGRPSEVLCGWWIHFDWSGLPDTTRLRTPPA
                     NVPAVGLEDKDWHYQLYLPSSRVFAVYRSGEFGLADEHGSKIPSGGYGTTYTWFKRTID
                     QFAEELFRNRVIIFRPPGHDGHRSYPMTDHADPDVYEPYVEAVAEQTAAHFHALLPNRP
                     "
     gene            complement(5264..5719)
                     /locus_tag="DWB77_RS01515"
                     /old_locus_tag="DWB77_00312"
     CDS             complement(5264..5719)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959371.1"
                     /locus_tag="DWB77_RS01515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00312"
                     /product="hypothetical protein"
                     /protein_id="WP_120727233.1"
                     /transl_table=11
                     /translation="MTNGGTAVFVDVLMLAVSALAHEPWGFRFAALLTLQDQSVMGRGV
                     VGFDLADLDWGDTPQERAAAKDFLLRVLDLALSRHRWEELTYEPPRAEGYLRTYRAMVE
                     EFDVTTAHGGTGVLPGPQEAAMASCLRHRVLDALPFWEACVFCTAGV"
     misc_feature    complement(5330..5332)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6205..6612)
                     /locus_tag="DWB77_RS01520"
                     /old_locus_tag="DWB77_00313"
     CDS             complement(6205..6612)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010264431.1"
                     /locus_tag="DWB77_RS01520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00313"
                     /product="hypothetical protein"
                     /protein_id="WP_120719535.1"
                     /transl_table=11
                     /translation="MSWDVLLLHLPDDVASVQDIPDGFSPHPLGSQRDVLAAVARAAPE
                     ADLSDPAWGELCGATWSIELNIGADSPVDTVMLHIRGSGDDVLTSVTRLGRALGCKALD
                     CSTGKVLADQEPTGWHAFQNYRDRVTGVLPD"
     misc_feature    complement(6589..6591)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6660..7163)
                     /locus_tag="DWB77_RS01525"
                     /old_locus_tag="DWB77_00314"
     CDS             complement(6660..7163)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS01525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_00314"
                     /product="hypothetical protein"
                     /protein_id="WP_342777902.1"
                     /transl_table=11
                     /translation="MALLVSYVSGPLLVEAHGSDVSGGWWNGWTLPLIRWELNMALPKK
                     GSRRIVVDGVAYRWRVRRRPTYDQGMSWSPLIYAVEHTEAAGTTLIVRTDRPHPGNWMS
                     ELTSPALPSSVAAAIQTARAKGWAPEAPGSPFLLDEVEVTVPVPFGTSIPESVLESLRA
                     GSDQ"
     gene            complement(7463..8890)
                     /gene="rox"
                     /locus_tag="DWB77_RS01530"
                     /old_locus_tag="DWB77_00315"
     CDS             complement(7463..8890)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene="rox"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003986161.1"
                     /locus_tag="DWB77_RS01530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00315"
                     /product="rifampin monooxygenase"
                     /protein_id="WP_120719536.1"
                     /transl_table=11
                     /translation="MFDVIVVGGGPTGLMLAGELRLHGVHALVLEKDAEPTRIVRSLGL
                     HARSVEVMDQRGLLERFLALGKRHPVGGFFAAIDKPAPDQLDTAHPYTLGIPQTTTDRL
                     LAEYAIELGVEIRRGCELVGLSQDEDGVTAELADGTRLRSRYLVGCDGGRSAVRKLLGV
                     GFPGEPSRVETLLGEVELTAAPDTLHAVITEVRKTQKRFGAMPLGDGVYRIVAPAEGVA
                     ADRTVPPTLDELKRQLRKLAGTDFGVHSPRWLSRFGDATRLAERYRTGRVLLAGDAAHV
                     HPPTGGQGLNLGIQDAFNLGWKLAAEVNGWAPEGLLDTYHTERHPVAADVLDNTRAQME
                     LMSVEPGPQAVRRLVSQLMDFEEVSRYLVEKITAIGVRYDFGEGHELLGRRLRDVELKR
                     GRLYELMRRGRGLLLDQTGRLSVAGWADRVDHVADTSKELDAPAVLLRPDGHVAWVGDD
                     QQDLLDRLGQWFGAAVS"
     gene            9694..9849
                     /locus_tag="DWB77_RS37460"
                     /old_locus_tag="DWB77_00316"
     CDS             9694..9849
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964026.1"
                     /locus_tag="DWB77_RS37460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00316"
                     /product="SflA family class IV lanthipeptide"
                     /protein_id="WP_162952331.1"
                     /transl_table=11
                     /translation="MSPTQLQIREAGPLDLEEQLIEFEDDVDPARRIEACLADPWVTAT
                     TRFACD"
     gene            10001..12781
                     /gene="lanL"
                     /locus_tag="DWB77_RS01535"
                     /old_locus_tag="DWB77_00317"
     CDS             10001..12781
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377564.1"
                     /locus_tag="DWB77_RS01535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00317"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_246033343.1"
                     /sec_met_domain="Pkinase (E-value: 6e-17, bitscore: 60.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 5.9e-20, bitscore:
                     70.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSAQQDDVRNARGDVQSARDDDVRNAPGDVQSARGDDLPVPWHG
                     DSRGTRHGAMPDQGGGPESEGPDEPVDDAAVLHRHLEVLLGDAPRRLVADEMWLYLLDP
                     AMPSYEHGWKLHVSTRAEGLAETMRLVAPVLLRHTCDAKFAVSTAVLRDLNSGERDPRL
                     VGKAVTIYPRVQDFVAIAHELADVLAGRIGPRVLSDRRVRSGAPVHYRYGPFRSAGADG
                     SMLVMTGPDGQTFTARAGARYRQPPWAADPFGRPAPAETSSTPLIGARYRITAGVARSP
                     RGDVFRGIDTVTGARVVVKQARAYMAEDAQGIDALGRLGHEHRVLAALDGVEGVPRLID
                     HVRHGEDEYLVMTDCGPTDLRRDVSQRGPYAARGSDSDRQLGSLARQLIGILDAIHARA
                     VVVADLKPHNVVLGSDGAVHVVDFGISALDGDRPAGATRGYSLPVYRPDAESDPADDLY
                     ALGATLHFALTGMDPVVVDPDRAVNRDRTLACLAAAAPGATLRPMRLLVAGLLSLDGAE
                     RSATARRFMAGLPLPAGAGGPSTAPPRPSPALLDEVIAHTVTMSVAAARNLCGRPGTHH
                     PGASLTLYAGAAGVGLELLHHQDRPGVAEAVAELARQTVRHPQLPFLNGSLYVGRTGID
                     VFLDAAAARYADLPARPAPSAPPLPDGTGDQIGGAAGAGTGQLVLAAQAETDGRAADAA
                     RHTALAADHVAALLARAADPAPELPRTASSSDAAYELGFAHGTAGIVHFLYAYQRVTAD
                     HSVRAAALAGLDVLAGRFPELLALAGRPEASRRYGSWCRGLAGIAALLIDVGTSEQDEA
                     LLDLGLSGARTCHRIAPRMSLVSQCCGLSGVGELLVDAALATGDTEYWSAAEDVASLIL
                     TRSGGTTRRPLFPDNTLTGSDVAWATGSSGVLTFLRRLRDRDTVRLWAPPGPVRP"
     gene            complement(12800..13204)
                     /locus_tag="DWB77_RS01540"
                     /old_locus_tag="DWB77_00318"
     CDS             complement(12800..13204)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020140619.1"
                     /locus_tag="DWB77_RS01540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00318"
                     /product="hypothetical protein"
                     /protein_id="WP_120719537.1"
                     /transl_table=11
                     /translation="MNPWSLLDIEQALRASWAADTCSPDDITRAGWGSDNPAWGHCDIT
                     ALIVHDIFGGDLVVGEVHLEGERHGFHWWNRLPSGLELDLTREQFIRGQSITAARVVPR
                     PPGPLPRRWGEYLLLRERVVEHLGPLPEPV"
     gene            13510..13941
                     /locus_tag="DWB77_RS01545"
                     /old_locus_tag="DWB77_00319"
     CDS             13510..13941
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954998.1"
                     /locus_tag="DWB77_RS01545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00319"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_120719538.1"
                     /transl_table=11
                     /translation="MSEISDLVALLDLQPHPEGGWFRETWRTGPSAVPDGYPGQRSFAT
                     GIYYLLHPGETSRWHRVRSDELWLWHRGGPLTLRLGGTGATAEEESASLLGPDVASGER
                     PQSLVPAGAWQCAEPAGDEPVLVSCVVAPGFDSEDFEMP"
     gene            14471..15073
                     /locus_tag="DWB77_RS01555"
                     /old_locus_tag="DWB77_00321"
     CDS             14471..15073
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049289.1"
                     /locus_tag="DWB77_RS01555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00321"
                     /product="YdcF family protein"
                     /protein_id="WP_120719540.1"
                     /transl_table=11
                     /translation="MLRRTGLAIAGVAALAWGEWLNWRWSQVLVGDGRGASEAVVVLGY
                     RNPQATANLINRWRVRAGIRSCAEGAHATCVIFSGGATGGGTAEAKLMADYAKSVLGFD
                     GTVLLEDRSATTWENITNVIPLLEDVDVDCIKIASQPAHALKARAYLRRQRPDLAERLV
                     RADDYRPGEWMVVKPLLALYGLWTLRGLKANERKVLL"
     gene            15410..16183
                     /locus_tag="DWB77_RS01565"
                     /old_locus_tag="DWB77_00322"
     CDS             15410..16183
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS01565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_00322"
                     /product="hypothetical protein"
                     /protein_id="WP_120719542.1"
                     /transl_table=11
                     /translation="MENWDELTITEQVLVHRAVNGTSTRGSAQHVTAVLRWAGAPGVPE
                     RRHALPAEELERVPELATATLRLVALEWLTVRRAPSSSFVQEDGPAVTGFELEQVVADP
                     ATWLMPSGNEDDLPALSLRATAEGHRRWEARAYAPDARPTIHQLDLTQDEDRIRVCAME
                     ASGWLTGPFGVLADLAGEELRAYVAAQLAPLLRLVRAGMIEVLHVAEPDAEATIIPPAD
                     LLDAFGDRELRCDDGDDWGIGFTCVLIQSLANALR"
     misc_feature    15557..15559
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17145..17699)
                     /locus_tag="DWB77_RS01570"
                     /old_locus_tag="DWB77_00323"
     CDS             complement(17145..17699)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DWB77_RS01570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DWB77_00323"
                     /product="hypothetical protein"
                     /protein_id="WP_162952332.1"
                     /transl_table=11
                     /translation="MTAVLGFPSLDRGCMRTKMLGCLFGVASMTAFALIGAPGAQAAPS
                     AASDSAHATTISVPAGQTSATMTVGGSTVTVSRSAPSVAVLTCTVSPGKPYHGTAGVTS
                     TVWAYCNSNAATLSFGTALYFYGSSVSQNNVTKHNCTSCYVTVTAPYQAGQWKSGAILG
                     YFDSTGNGQFTSEAYSATASL"
     misc_feature    complement(17717..17730)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     misc_feature    17861..17875
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.57"
                     /tool="antismash"
     misc_feature    17876..17890
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.84"
                     /tool="antismash"
     gene            complement(18349..19263)
                     /locus_tag="DWB77_RS01575"
                     /old_locus_tag="DWB77_00324"
     CDS             complement(18349..19263)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979141.1"
                     /locus_tag="DWB77_RS01575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00324"
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_120727239.1"
                     /sec_met_domain="PCMT (E-value: 1.4e-25, bitscore: 89.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEALSDELERLAVELRAACAAEIDGRTVGHFNDRPWLRAAFLEV
                     PREHFVPDRVWWPTPRADGLHHVIDRHERPRAWLKGVYRPRASLITQVADGAVRPEDGP
                     TDAPFTSAVSCSAVVVDMLHHLDPGPSDTALEIGTGSGYSTALLAQRVRPENLVTIEID
                     EQLADRARRSLADFRLRPAVVTGDGERGCPDRGPYTRIISTAAVRQIPRAWLDQAAPGA
                     VIVTPLHGPFGHDALLRLVADGQGGGAGRLVTGVAFMKMRGQRAERPFTDLGWPTVEGP
                     WPAYSEACYQVTVRDGRQRIRIC"
     gene            19682..20668
                     /locus_tag="DWB77_RS01580"
                     /old_locus_tag="DWB77_00325"
     CDS             19682..20668
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1251: luciferase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173445.1"
                     /locus_tag="DWB77_RS01580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00325"
                     /product="MsnO8 family LLM class oxidoreductase"
                     /protein_id="WP_120719544.1"
                     /transl_table=11
                     /translation="MINVPMSALEVAVVESGTRGVETLRDTAVFARKLEALGYRRIWYA
                     EHHHSPAIGAFPPVLLIAHAAASTSSIRLGSGGVLAPNHAPITLAEQFGTLAALHEDRI
                     DLGIGRGPGTFDEATARALRRGAGSATDQEYHDDVAAILSLLVDEVALGLLPEPWLLCS
                     STAGAALAARLGLPIAVAHHIRPDTTFAVLERYRAEFVPSQWCEQPRVLTCVEVICAET
                     EQEAAWRAGPMDVVKAGLLKGLSDIPFPTPADAAAHPFTPEERQALAGFRAQQACGTPE
                     TVVRRLAQLAAETGADELMLTTPVYDLDARVRSYELVKRYCEATTTP"
     misc_feature    20969..20987
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.9"
                     /tool="antismash"
     gene            21041..22330
                     /locus_tag="DWB77_RS01585"
                     /old_locus_tag="DWB77_00326"
     CDS             21041..22330
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020550984.1"
                     /locus_tag="DWB77_RS01585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DWB77_00326"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_120727241.1"
                     /transl_table=11
                     /translation="MSVDDSEQERTIRTGEHATRVRGPKVLVAGASIAGPALAHWLRRR
                     GAEATVVERAPELRPGGQAVDARGVAREVIRRMGLDATVRAACTDTAGAHTVDADGKVL
                     ETFRADDDGGDGFIADIEILRGDLSQVLYDDTRDGVEYVFGDRIAELAQDADGVDVLFA
                     GGDRRHFDLVIGADGLHSELRAMVFGPHERFLHHLGHMLAFYSVPNEFGLDRWLLEYQD
                     HESGRSALLRPIQDAARAMAMFYLPSPDFDVDHRDVAAQKRLLRERMAGLGWLVPDILA
                     HLDDTPDFYLDQVAQVVMDRWSSGRVALLGDAAFSSSPMSGQGTGLALVGAYVLAGELA
                     AADWDPEAGFARYEARMRSFVEANQEIGRMNARSRDVPGADAEPQPDFTSAWFTDLVGR
                     AINGVELPEYGGLPDSATSAGSPIPSSNKP"
     misc_feature    22426..22439
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
ORIGIN
        1 cctgtgggac ctcgaaaccg gcaaggagct gtggaagcag gcggagggcg agacccggct
       61 gacgccccgc cgcttctccg cgaacggcgt gttgtacggc gacaccgaca aggcgggcgg
      121 gtcaggcacg agcgcgctcg cggtggacgc ccacacgaag aaggtgctgg ccaaggacct
      181 gccgagcgac ggcattccgc tgttttcccg gtccaccggc tatgggtacc tcaccacgga
      241 cgacggcttc ttcgtcttcc cggcggagcg ccaggacggg tgaggacgac gggacacccc
      301 cacagacgtc tttgcatcgt tgagacagga ctgatcacga gccgccacga cctcactccg
      361 agccaaaaac ctcagtagag gtagcggttc acaacgtccc gcagtctctc gtcctcaccc
      421 cgcagcagta gcgcacgagg ttcgtcgacg ggaacgcgca gaatctccca gtcctctgcg
      481 tctcgctcac cgtcgccctc ctccccgtag cccccgtccg tgtcggaggg gggctacggc
      541 gccatgacat agggctcgtc gtactcgtcg ggtgactgcg ccggttccgg gcggcggcac
      601 tgccatacgg tgccgtagtt ccggaccccg ggtcagttcc ggcaggtggt aggcggagaa
      661 ggtcacctga agaagacgcg caacgaagcg ggatggctgg tcatcgccgt ccgcattgtc
      721 ggccagggac agccatgggt catcgaggcg gaaccagtgc gcgacgccgt gagcgcctgc
      781 cgccagcacc atcgtcgact cccaccaacc gccagactga ccagcaagct atgccttatc
      841 cagagcggtg accacgtggt ccagttctga cggcatgacc gcgatcagga cctctccgtc
      901 ggacgaatcg cattccgcga tccgggaccc cggattaatt gccacagcct cacgcaggga
      961 cggcgagcgg aatccggtct gcaacagatc ggtcggcaga gcaacttcct gcttaccgta
     1021 ggaagacttc catacgacgg acccagcgct gatcagcaga cgtccggccc gccaacgagg
     1081 gctccgggca ggccacttca ccatgcacgg cactccagca ggctccccgg cggctatcgc
     1141 ggcagacctc tgctgctgct tccggcgcat cagccaccca acgaaagccg caccgcccat
     1201 ccccatcaag agttcgatca ctctcgcatt caagcacgcg cagcgaggtc agcccggagc
     1261 gctatggccg ggatccagcg cgcggacgcc cgcgaagcca cgccaggccg accggtacca
     1321 gaacccgtag cccaagaggt actgatgggc agcggcatcg aaaaggcctc cggccgtccc
     1381 gcgtacaggc gggggccgga ggcctcaagt cgggggcgag gaaagcgagg ggactaattt
     1441 caaggagttt ggagaaggaa gccccctcat ggcctcgcca cggacacgtt aacagtcagg
     1501 cgggaatcaa gtcacccagg ttttcagggg tgatgatccg tgactgcggg tgcaggccgt
     1561 cggggcgctc cagcccgatg tacgtgacgg gacccgccgg gaccgacttg ccgtcccacg
     1621 aggtgaccgt cgtcgcgctg ccggtcatca gctcggtgag gtagcgaacg gtgagctgct
     1681 cgcgctcgac gatgccgcgc agcagcgtcg cgaccgtcac ccggttctcc tccacccggt
     1741 tcgccgaggg agcccccttc aggtacaagt gcagccactt ggcccgccat gtgccatcgg
     1801 atccgcgcag gaagaccaac ggcagggcga cccggcccgg accccgcagt tccgacttca
     1861 tgcgtacggt gcgcgcctcg aacgggagac ccttctgctc gccctcgcgc agcatgaatc
     1921 cgaagaacga ctcctcgacc tcctcgaagc cctccccgga gaagatgttg atctgcggca
     1981 cgatgcagtg ggcgcgcacg gcccccaggc gcaggttgat gaactccgac gcgccgtcgg
     2041 gggcgtccgt gatgtcgccg gaatgctccc cctcgacacc acgcaaattg gtgtacgaca
     2101 gccaggaggc ggtcgagtag tcggcattga ggagcgccgc ggacaggtcg aagtcggtgg
     2161 tgcgctcgct ctgcttccag tggacgaaga agcggagcag ctctccgtcg acgcgggaga
     2221 ccgagccgcg cggcagcact ccgagtccgg acgcggtggc cttgccactc agcggcaagg
     2281 ccacgtccag gacgtccggg tcgatcaaca ggtgctcgcg ggccgccagt cggcgacgca
     2341 gctccgtgtc gagcacggtg atcagccgct cgcgctcggg cgcgaacacc ggacgacggg
     2401 tgtcgtcggt gacccaggcc cggccgaggc ggttgatgaa cacgcgccgc tcactggttt
     2461 cccgctcacg gttgtgcagg tgctggcgca ccgacaacag gacgcggccg gagacgtcgg
     2521 caacgctccg ctcggcggcg gccacgaccg cgtcgcgctc gtcctgggtg aaggagtcgc
     2581 gcagcaactg gtccagggcg cgcagcagct tgccgggcgc gaccttgagc agcccgaccg
     2641 cggcggtggt gtcgccacgg gcgagcaact cctcgacccg gctgtcgaga gaccgtgccg
     2701 tcttctcgcc ccgggcaacg gcgaacacgt cggccgcgtg cggccactgc gggtattcgt
     2761 gcgggtgcag ccgctcgccg agtcgcttcc acatctcgcg gtcggcatgt acgtcagcga
     2821 gtttcgccgg ccccgcggcg atgaccgcgt cgaggcccgc gagcagtgcc cggcgcatcg
     2881 aacggggcag gctccgcagc cgcgtcggct cccgcagcgt cacgtcgccg ccgacgagcg
     2941 cgcaagccag gcgcaaaacg tcggtgaccg tgtccagcag cggggccgct ccggtcatca
     3001 gccgggcctg gttgaccacg gcccggttct cccgcacggg gatctcctgc ggctgaggcc
     3061 cgtcggcgca gtggccggcg agatcctgca ggtcgcgcag gccgtcctca ccaagtgggg
     3121 tggcacggcc cgccaacgcc aagtaaagcg cggtcagttc gtcaccgagc gaggcgccca
     3181 ggtgaaggac cgtgatgcgg tcgccggccg cggcgatcag ctcgtcgtgg tgggcgagca
     3241 tctcggcgta ggtgtgccgg gggttcccgt acgaggggag agtgagcagg tccaccacac
     3301 cggtgctcag ctgctccagc gtgctcgtgc gcgtggtggc atcggcgagc gcgtcggcga
     3361 tgcactccat ccagaagtcg agggtgtccg ggacgttggc ggggaagtcg atgaagtacg
     3421 cgttgtgctg gacgtgatcg ccgaccatct cccggacggt gtgcagcgtc cgcacggcgg
     3481 tgtcgacgac cgcctcctcg gagaaccccg acaggtgggc gaacaactct gctgagagct
     3541 tgaagcccac ggacatcaac gcggcgtcga actgccgcgc cgcgacggcg ccttgaccgg
     3601 cggcccccgt gaggcggggg acgcggtggg tgtgccggat gaccaggggt tcgagtcggt
     3661 ggaccatccc gggatgatcc cagggcgggg caagcggtcg cacccggatt tcttcggaca
     3721 ggacaggagg cgacgatcag gcggtggatg gcggccatgg tcggctcgtc tccgaggagg
     3781 acgggctcga ccagagcgat gttcgacctg ggacctaccg gactcaggga tccgttcgtt
     3841 gcccgtggtc cgggggcggg cgggctgtca tggttgacat atggccttgc agatctcgta
     3901 caggggtggt cggctcggtg aggatctcga catcaccgtc tactggttcc cccgggagcc
     3961 ggaccggccc gcgcactacg tctccgacat cctgggcgca tggcgcgtgt cgataccgag
     4021 ggacgtggac gcgagcggta ccccgcagga gatcgtgtca tggaacgacg ccgcggcctc
     4081 gttcgtgcag cgaatcgccg cggaggatcg cgagctcgcc aaagcggagc gtgctatcgg
     4141 gcgttggggt ctgctggtga cgcgtcgacg ggcacagttg aggtacgacg acgcccggac
     4201 atccttcctg gaggccgtgc gatcggcggc agcggcctac cagccggtcc gggacgtcat
     4261 cgaagcgcgc ctggccgagc gcgaggccca tgcgcgcgag gcggcccggc gtgcgtatca
     4321 ggggaaagag cgtcagtggc gggacgaagc ggcccggttc agggaatggg agcgccgtca
     4381 ggaggtggct gatcggccgc tgcccggcgg actcagtccc cgcgagatgg ccgccagcgg
     4441 ggacgccccc gtcaactggc cggcagaagt gcggtcgttg gtgggtgaca cctcctcctg
     4501 gtggacaagt gttcgcgcgt cggaacgcaa caggcgggcg aacgcacaag ccgtacggaa
     4561 agtcaccgag gcgatcaacg gggtggcagc cgcgctggag gagaccggcc gaccgggcat
     4621 cagcacgatc agggggcgcc cctccgaagt gctgtgcgga tggtggatcc acttcgactg
     4681 gtccggcctg cccgacacga cccggctgcg gacaccgcct gcgaacgtgc ccgctgtggg
     4741 cctggaggac aaggactggc actaccagct gtacctgccg tcctcccggg ttttcgccgt
     4801 gtaccggtcc ggcgagttcg ggttggccga cgaacacggt tccaagatcc cgtcgggggg
     4861 ctacggcact acgtacacct ggttcaagcg aaccatcgac caattcgcgg aggagctgtt
     4921 ccgcaaccgg gtcatcatct tccggccccc cggtcacgac ggtcaccggt cctacccgat
     4981 gaccgaccac gcggaccccg acgtgtacga gccctacgtc gaagccgtgg cagagcagac
     5041 ggcggctcac ttccacgccc tgctcccgaa ccggccgtag ggcacccggc gccatacctg
     5101 ccaccgagag gtcagcgggc gtcccgccac tgaccattgc tcggccgcca acaggccgcg
     5161 caactggggg cattcgccat cgcgcatcgg gacggcgagt cacaactgga gaaacaccgt
     5221 gtgtgttggg ggtgtggggg gcaagaccga ccggttgtgc ctctcagacc ccggccgtgc
     5281 agaagacgca cgcctcccag aacggcagcg cgtccagtac ccggtggcgt aaacatgagg
     5341 ccatcgcggc ctcctgcggc ccgggcagga ctcctgtgcc gccgtgcgcg gtcgtgacgt
     5401 cgaattcctc caccatggcc cggtacgtgc gcaggtaccc ctcggcccgg ggtggctcgt
     5461 atgtcagttc ctcccaccgg tgccgggaga gcgccagatc gaggacgcgc agcaggaagt
     5521 ccttggcggc agcccgctcc tgtggtgtgt ccccccagtc gagatccgcc aggtcgaacc
     5581 cgaccacccc acgccccatc acgctctggt cctggagcgt cagcagcgcg gcgaagcgaa
     5641 aaccccacgg ctcgtgggcc agcgcggaca cggcgagcat cagcacgtcc acgaacaccg
     5701 ctgtgccgcc gttggtcatc tccaggtacc ggccctcacg gccgcggctg ccaaacacgt
     5761 tcacgtcatg agaatagaga gcggggcagg cggacgtacg caatgcccgg tcgtcaggat
     5821 gcgtggccgt agtgtcagtg cctcgcccta gattccgggc gatggggccg gaacggggcc
     5881 accagcactg gagaacggca agtctccctg gtctgcgcgg gggtggttac ggcccaaccg
     5941 gcgtccaggc atccgttgag tgccacactg cagcccgaca gcccggcccc atcacaccct
     6001 tacggcacat tctgcggtaa gggctgagcc gacgggccgg tcaccgcact cgcagcccgg
     6061 tttctcagag cgtgatgacc atggggcgag acaggcagga ccaacggtca agtctgcgga
     6121 gctcagcggc gcaacggccc tcccatacct ccgtgctcgc atgacacgcc tctacctgct
     6181 caacgacgcg catgcaggca accgtcagtc gggaaggacg ccagtcaccc ggtctcggta
     6241 gttctggaac gcatgccagc ctgtgggctc ctggtcggcg agcacctttc cggtggagca
     6301 gtccagggcc ttgcagccca aggccctgcc aagtcgggtg acagaggtca gtacgtcgtc
     6361 gccggatcca cggatgtgga gcatgaccgt gtccactgga ctgtcggcac caatgttgag
     6421 ctcgatcgac caggtggctc cgcacagttc gccccaggcc ggatctgaaa gatcggcctc
     6481 aggcgcggct cgcgcgacgg cggcgagcac gtcgcgctga gatccgagag ggtgcgggct
     6541 aaagccgtcg ggtatgtcct gaacagaggc gacgtcgtcg ggcaaatgta agagaagcac
     6601 gtcccagctc atgtgaacct ttcaatggag gggtggtgaa cggcaggagc gggccctggc
     6661 tactgatccg accccgcgcg caagctctcg aggacgcttt cgggtatgga cgtgccgaac
     6721 ggcactggca ctgtgacttc gacttcgtcc aggaggaaag gcgacccggg agcttcgggc
     6781 gcccagccct tggcacgggc ggtttgaatg gctgcggcaa cgctggaagg cagagcggga
     6841 ctggtcagct cactcatcca gttgccagga tgggggcgat cggtgcgaac aatgagcgtg
     6901 gtgcccgcag cctccgtgtg ttcgaccgcg tagatcaggg gcgaccagga cattccttgg
     6961 tcgtaggtcg gccgtcgtcg cactctccac ctataggcga cgccgtcgac gacgatgcgt
     7021 cgtgagccct tcttgggcag tgccatgttc agctcccagc ggatcaacgg cagagtccag
     7081 ccattccacc acccaccact gacatcactg ccgtgagcct ccacaagaag tggaccggag
     7141 acgtaactca ccaacagcgc cacggagttg gatggaacgt ggcagagcaa tgttccggac
     7201 gcgctcacgc ccggcgtgcc gcctgccggc cagcgcgtcg aggacgtatc accgctgtgt
     7261 gctgcccgta tttctgctga ggaaatgccc atgaaagaca ctcatgctct ggatatctcc
     7321 tcgccatacc cttccgagct ggtcgctctg cggcctggag cgggtagagc gtctcctcac
     7381 gagcgacagc tttgcgtccc cgttccgtcc gcgcaggcct ggtgagctgc gggcccggcg
     7441 ggctttcggg ccgtatgcac gctcagctga ccgcagcgcc gaaccactgg ccaagccggt
     7501 cgagcagatc ctgctgatcg tcgccaaccc acgccacatg gccgtccggc cgcagcagca
     7561 ccgcaggcgc gtccagttcc ttgctggtgt cggcgacgtg gtcgactcga tctgcccagc
     7621 ctgccaccga gaggcggccg gtctggtcga gcagcagccc gcggcctcgg cgcatcagct
     7681 cgtagaggcg accgcgcttc agttccacgt cccggagtcg tcggccgagc agttcatgcc
     7741 cctcaccgaa gtcgtagcgg accccaatcg ccgtgatctt ctccaccagg taccggctca
     7801 cctcctcgaa gtccatcagt tgcgacacca gtcggcgcac tgcttgggga cccggctcga
     7861 cggacatcag ctccatctgc gcgcgggtgt tgtccagcac atcggcggcc accgggtgcc
     7921 gttcggtgtg gtacgtgtcc agcagtccct ccggtgccca gccgttgact tcggcggcca
     7981 gcttccagcc caggttgaac gcgtcctgga tgccgaggtt gagcccctgg ccgccggtcg
     8041 gcgggtggac gtgtgccgcg tcgccggcca gcagcacccg gccggtccgg tagcgctcgg
     8101 ccagcctggt ggcgtcaccg aagcgggaga gccatcgcgg tgagtggacg ccgaagtcgg
     8161 tgccggcgag cttccgtagc tgccgcttca gctcgtccag ggtcggcggg accgtgcggt
     8221 ccgcggccac cccttcggcg ggtgcgacga tgcggtatac cccgtccccg aggggcatgg
     8281 cgccgaaccg cttctgggtc ttgcggactt cagtgatcac ggcgtgcagc gtgtccggtg
     8341 ccgcggtcaa ttccacctcg cccagaagtg tctcgaccct ggagggctca ccggggaagc
     8401 cgacgccgag cagcttgcgc accgcgctac ggccgccgtc gcacccgacg aggtagcgcg
     8461 agcgcagtcg cgtaccgtcg gcaagttcgg cggtcacgcc gtcttcgtcc tggctcagcc
     8521 ctacgagttc gcaacctcgc cggatctcga cgccgagttc gatggcgtac tcggcaagca
     8581 ggcgatcggt ggtggtctgc gggatgccaa gggtgtacgg atgtgcggtg tccaactggt
     8641 ccggcgccgg cttgtcaatg gcggcgaaga atccaccgac cgggtgccgc ttgccgagcg
     8701 cgaggaaccg ctccagcaga cctcgctggt ccatcacctc gacactgcgc gcgtgcaggc
     8761 cgagcgagcg gacgatcctg gtcggctccg cgtccttctc caacacgagc gcgtggacgc
     8821 cgtgcagccg caactcgccg gccagcatca agccggtcgg tccgccgccg acaacgatca
     8881 catcaaacat gccccccctt gagaagagtt tcacgtcggc cagctgctgc tgctctactc
     8941 agtccggcgg cgcgcacacc cggccctccg cggcgcgccg cgagcccgca accacaccac
     9001 gcgtcccacc gggggcgagt cccaccgggg ggcgagtccc accggcggtt tccatcccga
     9061 gtcctggcct cggccgacga ttctgcgcca ccacccgggc cttgccgcaa ggcccccctt
     9121 gcgatataag ttgaaagtgg caaggagtag atgacctcct tgcctttctt ttttgctgcc
     9181 cgttgcgaac ggacaaatcc ctccggcgtc gggctcgcga cgcgagccga tatcgagatg
     9241 tggtcgccaa gtatctgcca ttgcggatga agggtcgaca agtcacccgg acaagggcgg
     9301 cgggcagcgt gacacgggcg cgcaccgcaa cgggcagggg ggcgagggca gttgctcggg
     9361 cggccggctc ggcgaagtgc ccggactggc cggcgcggac gagccaggcg gcgccttcgg
     9421 ggcgcggcat ttcgcgcccc gggtccgtct gcgtgatccg cgcctacgcc cgcagccgta
     9481 cggccggcgg ccggcggcag gcggccggca cccagggccg cggggttttc tgccgtcttt
     9541 ctttccaaca ggcttcagtt ctggccacga ctccggtgta gtggcttctg ctggtcaacc
     9601 gcttgcgcat atgccgccga ccagtgcgcc acgccatgca cggattcagg acgaccacct
     9661 gttcattcac tggcagaggc aggaaggatc gctatgagcc ccacgcaact ccagatccgc
     9721 gaggcgggtc cgctcgacct cgaggagcag ctcatcgagt tcgaggacga cgtggacccc
     9781 gcccgtcgca tcgaggcctg tctggccgac ccgtgggtca ccgccaccac acggttcgcc
     9841 tgcgactgag ccggttcggc cagcacggcc ccggcacttg aggccggggc catgctggcg
     9901 tccggagcgc ggcacggcag acacgcggtg cggaaggccg ggatccaggg tccgttgggt
     9961 ggaatccggt ggcggcaacc ggggtggagg tggggaccgc atgcggtcgg cccagcaaga
    10021 cgacgtacgg aacgcgcgcg gcgatgtaca gagcgcgcgc gacgacgacg tacggaacgc
    10081 gcccggcgac gtacagagcg cgcgcggcga cgacctgccg gtcccatggc acggggactc
    10141 ccgcgggacg cgacacggtg ccatgccgga ccaggggggc gggccggaga gcgagggccc
    10201 agacgagccc gtggacgacg cggcggtatt gcatcgtcac cttgaggtgt tgctcggaga
    10261 cgccccgcga cggctcgtcg cggacgagat gtggctctac ctcctcgacc cggccatgcc
    10321 ctcgtacgag cacggctgga agctccacgt gtcgacccgg gccgaaggac tcgctgagac
    10381 catgcgcctg gtcgctccgg tcctgctgcg gcatacctgc gacgccaagt tcgcggtgag
    10441 caccgccgtg ctgcgtgacc tcaacagcgg cgagcgggat ccgcgactcg tcggcaaggc
    10501 agtcacgatc tatccgcgcg tccaggactt cgtggccatc gcccatgagc tggccgatgt
    10561 cctggccggc cgcatcggcc cccgcgtgct cagcgaccgc cgtgtgcgaa gcggcgcacc
    10621 cgtccactac cggtacggcc cgttccggtc tgccggggcc gacggaagca tgctcgtcat
    10681 gactggtccc gacgggcaga ccttcaccgc tcgcgcggga gcccgatacc gtcaacctcc
    10741 ttgggccgcc gacccgttcg gccgccccgc gcccgccgag acctcgtcca ccccgctgat
    10801 cggcgcccgc taccgcatca ccgccggtgt cgcgcgctcg cctcgcggag acgtgttccg
    10861 gggcatcgac accgtgaccg gcgcccgggt ggtcgtcaaa caggccaggg cgtacatggc
    10921 ggaggacgcg caggggatcg acgcactcgg ccgactggga cacgagcacc gggttctggc
    10981 ggcgctcgac ggcgtcgagg gtgtcccccg cctgatcgac catgtgcggc acggcgagga
    11041 cgagtacctg gtcatgaccg actgcgggcc gacggatctg cgccgcgacg tgtcgcagcg
    11101 cggcccgtat gccgcgcgcg gcagcgactc ggatcgtcaa ctaggctccc tggcacgtca
    11161 gttgataggc attctcgacg cgatccacgc ccgcgccgtc gtggtcgcgg acctcaagcc
    11221 ccacaacgtg gtgctcggct ccgacggcgc cgtccacgtc gtcgacttcg gcatcagtgc
    11281 cctggacggc gaccgtcccg ccggcgcgac gcgtggttac tccctcccgg tgtaccggcc
    11341 cgacgccgag tccgacccgg cggacgatct ttatgcgctg ggagcgaccc tgcacttcgc
    11401 gctcaccggc atggacccgg tcgtcgtcga ccccgaccgc gcggtcaacc gggaccggac
    11461 cctggcctgt ctggccgccg cggcccccgg cgccacactg cgcccgatgc gcctcctggt
    11521 cgcaggcctg ctgagtctcg acggggccga acggagcgcc accgcaaggc ggttcatggc
    11581 gggcctgccc ctgccggccg gtgccggtgg cccgtcgacg gccccaccac gcccctcccc
    11641 cgccctcctc gacgaagtga tcgcccacac ggtcaccatg agtgtggccg cggcgcggaa
    11701 cctgtgcggg cggcccggca cacaccatcc cggcgcgtcg ctcacgctct acgcgggcgc
    11761 ggccggtgtg ggactggagc tgctgcacca ccaagaccgg ccgggcgttg cggaggccgt
    11821 cgccgaactg gcccgccaga ccgtccgcca tccacaactc ccgttcctca acgggtcgtt
    11881 gtacgtcggc cggaccggta tcgacgtgtt cctcgacgcc gcagccgcac gatacgcaga
    11941 ccttccggcc cgccccgcac cttcggcccc tccccttccc gacgggaccg gcgaccagat
    12001 cggcggagcc gcaggcgccg gcaccggcca actggtcctg gcagcgcagg ccgaaaccga
    12061 cggacgcgcc gccgatgccg cccggcacac ggctctcgcc gcagaccatg tggccgcgct
    12121 cctcgcccgc gcggcggacc cggcccccga gctcccgcgg acggcatcgt cgtcggacgc
    12181 ggcgtacgaa ctcggctttg ctcacggcac cgcgggcatc gtgcacttcc tctacgcgta
    12241 tcagcgggtc accgccgacc attcggtacg cgccgccgcg ttggccggcc tcgatgtcct
    12301 cgcgggccgc ttcccggagc tgctggccct ggccggccgc cccgaagcca gccgtcgcta
    12361 cggctcgtgg tgccggggac tcgcgggcat cgcggccctc ctgatcgacg tgggaaccag
    12421 cgaacaggac gaggcactcc tcgacctcgg cctgagcggc gcccggacct gtcaccgcat
    12481 cgctccacgg atgagtctgg tgtcccagtg ctgcggcctg tcgggcgtcg gtgagctgct
    12541 cgtcgatgcg gcgctcgcta cgggcgacac agagtactgg tccgcggccg aggacgtcgc
    12601 ctccctcatc ctgacgcgca gcggcggcac cacacgccgc cctttgtttc ccgacaacac
    12661 cctcaccggc tccgacgtgg cctgggccac cggcagttcg ggcgtgctca cctttctgcg
    12721 ccgactgcgc gaccgggaca ccgtccggct gtgggcaccg ccaggccccg tacgtccatg
    12781 accgctcccg ccgcctcggt cagaccggct ccggcagggg acccaggtgc tcgacgaccc
    12841 gctcgcgcag gaggaggtat tcgccccagc gacgcggcag cgggcccggc gggcgaggga
    12901 caacccgggc cgcggtgatg ctctgtcccc gtatgaactg ctcgcgcgtc aggtcgagtt
    12961 ccagaccact gggcagtcgg ttccaccagt ggaatccgtg ccgctcccct tcgaggtgga
    13021 cctcgccgac cacgaggtcg ccgccgaaga tgtcgtggac gatcagagcc gtgatgtcgc
    13081 agtgccccca ggccgggttg tcggaccccc aaccggcgcg ggtgatgtcg tccggggaac
    13141 atgtgtcggc ggcccaactc gcccgcaggg cttgttcgat gtcgagcaga ctccaagggt
    13201 tcatggcccc accatcgcag ccaccactga caacgagggc gccggcggac cgtgctgccc
    13261 gccgtcccgc gcgccggcgt gtggcctcgt cgtccgggcc gtccgggccg tccgggccgt
    13321 ccggacacgc tcccgtcctg ttcccgttgg ccccgcgcga gcgcgaagct tcgctccccg
    13381 cacgacagcg cacgacagcg cgtgcgagca tctccgcccg ccaccaccag aggcgacgtg
    13441 cgtggccggt gacgcgccgc ccggtaggcc cgttgtgatg gccctcgcgg tgcgccagga
    13501 tgtctgccca tgagcgagat ttccgacctg gtcgccctgc ttgacctgca accgcacccg
    13561 gaaggcgggt ggttccggga gacgtggcgt accgggccga gcgccgttcc ggatggatat
    13621 ccggggcagc gttccttcgc gaccggcatc tactacctcc tgcatcccgg tgagacgtcc
    13681 cggtggcacc gcgtgcggtc ggacgaactc tggctgtggc accgaggcgg tcctctgacg
    13741 ctccgcctcg gcggaaccgg tgccaccgcc gaggaggagt ccgcctcgct cctcggacct
    13801 gatgtcgcct cgggggaacg gccccagtcc ctggtaccgg ccggcgcatg gcagtgcgcg
    13861 gagccggccg gtgacgagcc ggtcctggtc tcgtgtgtcg tcgccccggg cttcgactcc
    13921 gaggacttcg agatgccgta agtgccggta gccggtgcgg ggcgtccctg gtgtccgtgg
    13981 cgtccgtggc gtccgcaccg gggatgtcca ggacgccggc gtgcccgagg tcgacggcgt
    14041 ccttcagcaa ctccgcgccg accaggatcc attccccatc ccgtatcggc agcgggcggg
    14101 cgcccgcccg ggcggcgacg aggtggcgcg gcacacaccc gcctccccgg ccggccgtcc
    14161 cgagagggcc ggaaacagga cgtgcgtgag cagttggctc accccgaccg gggcgagggc
    14221 gccgacgtcc gccaggcgca gcagcatgcc cagcacgtgt ggcccggtcg gggcgagctc
    14281 ggcgacgcgg ctggtcagcc gctcccccgc ggcatggggg gctgtggcgg gcaggtactc
    14341 gagaaacggg gccgcgggtc acacactggc cgccgtgtcg gcccagcagc agatgcgggg
    14401 cgtactcctg aaaagcggca gcgcggctgg ttccccgtgg ctcggcgccg aggtgcccta
    14461 gagtcgccgc atgctgcgaa gaacagggct ggcgatagct ggggttgcag ccctggcctg
    14521 gggcgagtgg ttgaactggc gctggtctca agttctcgtg ggggacggca ggggcgcctc
    14581 cgaggccgtg gtggtgttgg ggtaccggaa tccacaagcg acggcgaacc tgatcaaccg
    14641 atggcgagtc cgtgccggaa tccgctcatg cgccgaaggt gcgcatgcga cctgcgtgat
    14701 cttcagcggc ggcgcgaccg gcggcggcac tgcggaggcc aagttgatgg ctgactacgc
    14761 gaaatcggtt cttgggttcg atggcacagt gctcctcgag gaccgaagcg cgacgacgtg
    14821 ggaaaacatc acgaacgtca tcccgctgct tgaggacgtg gacgtggact gcatcaagat
    14881 cgcttctcag ccggctcatg cgctcaaggc gcgagcgtac ttgcggcggc aacggcccga
    14941 tcttgcggag aggctggtgc gcgctgacga ctaccgccct ggcgagtgga tggtcgtgaa
    15001 accgctgctg gccctatacg gactttggac actccgcggc ctcaaggcca acgagcggaa
    15061 ggtcttgctg tagacgggcg cgctatcgcg tggctcgcgc atggtggctc gtgacccgac
    15121 agggcggcag atgatgctgc atcccggagc aaggcaagct tcatggattg ccggctgacc
    15181 gttgcggcgc gagtggccgt cggttgttcg cgcgtcggag tttctgggcg gccgtcgtca
    15241 tggttgtcgt ggccggctcc gctttcgtgg tcagccaggc ctcggcgggc accgtgcgat
    15301 gcccaccggc ccgtgcccaa gtcgggcgct ctggccgctg tgccggggcc ggatccacgg
    15361 gcggaaatca tgcacgtcat ggcaggcgat tgtgtcagca tcgcctgcca tggagaactg
    15421 ggacgaactg accatcacgg aacaggtgct ggtccaccgc gctgtcaacg gcaccagtac
    15481 tcgcggcagc gcgcagcatg tcacggccgt gctgcgctgg gcgggcgcgc ccggggtgcc
    15541 cgagcgccgc cacgccttac cggcggagga gctggagcgg gtaccggagc tggcgacggc
    15601 aacgcttcgg ctggtcgcgc tggagtggtt gacggtgcgc cgggctccga gcagcagctt
    15661 cgtccaggag gacggcccgg cggtcacggg cttcgaactg gagcaggtgg tggccgaccc
    15721 ggcgacgtgg ttgatgccat cgggcaacga ggacgacctg cccgccctct cgctgcgggc
    15781 caccgctgag ggtcaccgcc gctgggaggc ccgggcgtac gcaccggacg ccaggccaac
    15841 catccaccag ctggacctca cacaggacga ggaccggatc cgggtgtgtg ccatggaagc
    15901 gagcggctgg ctgaccggcc cgttcggggt cctcgccgat ctggcgggcg aggagctgcg
    15961 ggcgtacgtg gcggcccaac tcgccccgct gctccggctc gtccgcgcgg gcatgatcga
    16021 ggtgctgcac gtcgcggagc cggacgccga ggcgacaatc atcccgccgg cggacctgct
    16081 ggacgctttt ggcgacaggg agctgcgctg cgacgacggc gacgactggg gcatcgggtt
    16141 cacctgcgtc ctgatccagt cgctggcgaa cgcgctccgt tagcccccgg aagccggagc
    16201 cccggaagca caccgaaagc gagcagccaa tgtcacttgg caacctgtca ggaccgcttg
    16261 cttacgggtt cgaggagcgc cgacgggtct gtcgacgcat cgcccccatg gatcggacat
    16321 ggatcgggcc tggatcggac atgccggaac gccacctatc gcgtcccggt gacctccgaa
    16381 ggacttgggc tcaggatgct gcgctcaggt ggcgacctcc gggggggaga gcgtccaggg
    16441 gtgggctgca ctcgaaccgg aggatctgcg ggagtgtgtg actccgctgc tgcccgccga
    16501 tcccgagcgt catcagctct gtcccgcgcg atcgcgttcg acgaaccggc cggcactcgg
    16561 ggcctgatgt acgtgctgcg aaccggcgga ccggtgtcat acggcacgac attgcagcgg
    16621 acgctacgga ctgcctcagc atgactgctc ggcaccgacg actggccgcg ccgaggtcgg
    16681 cgaccggccg gagcccctcg agggcctgct ggccggcgtg cggttcaact gccttctggg
    16741 catggacagt tgcgagagcg accgctatca ccacgtggca cccaaacacg aggcacccaa
    16801 aggggattgc atcgcccccg gcccgcatgc ggtttggttc cagcgaatcg cgggcggctg
    16861 ttgttgcggt cgcggccggg gtggcggtga agccgtcacc ccggccgcgg ttgtttcagg
    16921 gggaattacg caattcagcg atgcgggacg ctctttgatg ggtgatcaag cactgcgcgc
    16981 ttcacggtag caaccaggcc agcccggatc ccgcgcgaga tcggagccac gaacggcccg
    17041 gagctgtgca gggggtcctg ccttcgccgc tgccctcccc gcaacaaact tcaagcggct
    17101 tccgttcgat cgacaagctc catgatcgat acgacaacgg cccgttacag actcgccgtt
    17161 gcgctgtagg cctcgctggt gaactgcccg ttcccggtgc tgtcgaagta tccgagaatc
    17221 gcgcccgatt tccactgacc ggcctgatag ggcgccgtaa cggtcacata gcacgatgtg
    17281 cagttgtgtt tggtgacatt gttctggctg acgctggatc cgtagaagta cagggctgtc
    17341 ccgaacgaca gtgtggccgc gttgctgttg caatacgccc agaccgtgga tgtcacgccg
    17401 gcagtgccgt gatacggctt gccggggctg acggtgcagg tgagtacggc cacggagggg
    17461 gctgacctgg agacggtcac tgtgcttccg ccgaccgtca tggtcgcgct ggtctgaccg
    17521 gccggcacgc tgatggtggt cgcgtgggcg gagtcggagg cggcagacgg agcagcctga
    17581 gcgccggggg cgccgatgag tgcgaaggcg gtcatcgagg ccacaccgaa caggcagccc
    17641 aacattttag tgcgcatgca acctcgatcc agagaaggaa aaccgagcac cgcggtcaat
    17701 caccgcagcg cacagcttga ttggggtaaa acggccaagc gcaccatgta ctactcaagg
    17761 cgccagccgc agggcaagcg tcctaaggta cggaagtttg cgatcttcac gggccgatca
    17821 cgagctagat tctgcgggat ggcatccatg cggcgccgtg atgtttcagg ccattctgtt
    17881 tccgaaaatg gtcccgccgg attcacttgc gccgccctcg gctacacgca gtgaagatcc
    17941 atccggggct cctcggaacc tccccccgaa agcgcgttgt acaaggttgc gtttgggcag
    18001 gtcagggttg gcggcctggt acgagcaggt cgggtcccct cgccgcgcga ggtggtgtgg
    18061 gccgtcacgc cgagggcggc gcaccaaaga acgccaggag cacctcggac gtctggagcg
    18121 ttcctgacgc agcgccgctc ccgccagggg ctgttgcaga cgcaggacaa gtgggcagcc
    18181 agcctcgcgc gcgcggcacg cgctgcgggt tgggtgtcgg ggaccttggt cattccgaag
    18241 caactacgaa ccatccggcg gcagcccata ccgcccggtt ctccagtacc tgcctctcaa
    18301 ggcgggggcc ggaccaggtg gcgcgcggat ccccccggcg tcactgcctc agcagatgcg
    18361 gatcctctgg cgaccgtcgc gcaccgtgac ctgatagcaa gcttcgctgt acgccggcca
    18421 cggcccttcg accgtcggcc agccgaggtc ggtgaagggc cgctcggcgc gctgtccgcg
    18481 catcttcatg aaggcgacgc cagtgacgag gcggccggcg ccccctccct gcccgtcggc
    18541 gacgaggcga agcagggcgt catggccgaa gggcccgtgg agcggggtga cgatgacagc
    18601 gccgggtgcg gcctggtcga gccacgcccg cgggatctgc cggacggctg cggtggagat
    18661 gatcctcgtg tacggcccgc gatctggaca tcccctttcg ccgtcgccag tcacgaccgc
    18721 cgggcgcaga cggaagtcgg cgagcgaccg tcgggcacgg tcggcgagtt gttcgtcgat
    18781 ctcgatcgtc accaggttct cggggcggac gcgttgggcc agaagtgccg tgctgtatcc
    18841 ggagccggtg ccaatctcca gtgcggtgtc actggggccg gggtcgaggt ggtgcagcat
    18901 gtcgacgacg accgccgagc aggacacggc gctggtgaac ggtgcgtctg tagggccgtc
    18961 ctcgggccgt acggcgccat cggcgacttg cgtgatgagg gaagcgcggg gccggtaaac
    19021 gcccttgagc caggcccgtg ggcgctcgtg acggtcgatc acgtgatgca ggccgtccgc
    19081 acgcggcgtc ggccaccaca cccggtccgg cacgaaatgc tcgcgcggca cctccaagaa
    19141 tgccgcacgc agccagggcc ggtcattgaa gtgcccaacc gtccggccgt cgatctcggc
    19201 cgcgcacgcg gcccgcagct cgaccgccag tctctccagc tcgtcggaaa gagcctcaat
    19261 catcatccgg ctccggctcc ggggccggca tcgggttccc ggggtcgccc gggctcgacg
    19321 agtccccgcc aacctgcccg tcctgatcac cgcggcttcc acccatgacg ctccccaaga
    19381 cacccgatcg cgcgcacctc gacgcgatga cttcaccgca aggggaccag caactacgcg
    19441 gcgccgcaag cgagttgcgg attgtgcgaa tgcgccgtac accccctcca gatcacagct
    19501 acgatgcgcc ggccccagca ggggcacgcg ggagggcgac gacgaatagc gtcggtcccc
    19561 ctgctccgct tccgccgatt ccggtgcagg tcaacgccac gcctggcgct gggagttcac
    19621 gcctccctcg cggtctccgc cgctgggaac gctccgccga tcccttccct atgctggcgg
    19681 catgatcaat gtgccgatgt cagcgctgga agtcgcggtg gtcgagtcag ggacccgcgg
    19741 cgtggagacc ctgcgggaca ccgccgtctt cgctcgcaag ctcgaagcct tggggtaccg
    19801 aaggatctgg tacgccgagc accaccattc gcccgcgatc ggtgcgttcc cgcccgtgct
    19861 cctgattgcc cacgcggcgg cctcgacgtc ttcgatccgg ctcggttcgg gcggagtgct
    19921 ggcgcccaac catgcgccca tcacgctcgc ggagcagttc ggaacactgg ccgcgctgca
    19981 tgaggaccgt atcgacctgg gtatcggccg cggccctgga actttcgacg aggccaccgc
    20041 gcgcgcactg cgccgcggag cggggtcggc gacggaccag gagtaccacg acgacgtcgc
    20101 cgcgattctg tccctcctgg tcgacgaagt ggcgctcggc ctcctgccgg agccttggct
    20161 gctgtgctcc agcaccgcgg gggccgccct ggccgcgcga ctcggtctgc cgatcgctgt
    20221 cgcccaccac atccggcccg acaccacctt cgccgtgctg gagcgctacc gggccgagtt
    20281 cgtgccgtcc caatggtgtg agcagccccg ggtcctgacg tgtgtggagg tcatctgtgc
    20341 tgagacggag caggaagcgg catggcgagc cgggcccatg gacgtggtga aggccgggct
    20401 gctcaagggg ctgagcgaca tcccgttccc cacccctgcg gacgctgcgg cccatccctt
    20461 cacgccggag gaacggcagg cgctcgccgg attccgtgca cagcaggcgt gcggaacgcc
    20521 cgagaccgtg gtgcgccggc tcgcgcaact ggctgccgag accggagcgg acgaactcat
    20581 gctgaccacg cctgtctacg atctcgacgc ccgcgtccgc tcgtacgaac tcgtcaagag
    20641 gtactgcgag gccacgacaa ccccgtgagg gcgccacctc ggctctcgtc atgccgcagt
    20701 gccgcagtgc cgctgtgagc acacacgccg ctcgctcccg cccaacgcct gggccccagg
    20761 ggcgagttgt gtcctggagc cctgcgccct gccgaagtga ctgtccggcc ctgtccgcgt
    20821 gcgggcgcgg aggggaagca gcacggaatg gccctgatcg tcgcggctgc cgatccgcac
    20881 atgcctcgct ccgaacgaac gcgggagcgc ggacttaatc tccgtcgtgc ccgtgccgat
    20941 gagttgtgtg ccgatccgca gtcgatacgg ctggacacac ccacagccgt gggcctgtgc
    21001 tggggacgtt ccagcccagg agaagcatat ggaggcagtg atgagcgtcg acgactccga
    21061 gcaggagcgc accatccgga ccggcgaaca cgcgacgcgg gtgaggggcc ccaaggtgtt
    21121 ggtggcgggg gccagcatcg cgggccccgc gctggcccac tggctgcgcc gacgcggggc
    21181 cgaggccacc gtggtggagc gggctcctga gctgcggccc ggcggtcagg cggtggacgc
    21241 gcgcggggtc gccagggagg tcatccgacg catggggctc gacgcgacag tgcgcgcggc
    21301 atgcaccgac accgccggag cgcacaccgt ggacgcggac gggaaggtgt tggagacctt
    21361 ccgcgcggac gacgacggcg gcgacggatt catcgcggac atcgagatct tgcgcggaga
    21421 cctgtcccaa gtgctctacg acgacacccg cgacggcgtc gagtacgtct tcggcgaccg
    21481 gatcgccgag ctggcccagg acgcggacgg ggtcgacgtg ctcttcgcgg gcggcgaccg
    21541 gcggcacttc gacctggtga tcggggccga cgggctgcac tccgaactgc gggcgatggt
    21601 cttcggtccg catgagcggt tcctgcacca cctcggccac atgctggcct tctacagtgt
    21661 gcccaatgag ttcggactgg accgctggct gcttgagtac caggatcacg agtccggacg
    21721 ttcggccctc ctgcggccga tccaggacgc cgcccgggcg atggccatgt tctacctccc
    21781 gtcgcccgac ttcgacgtcg accaccgtga cgtcgcggcc cagaagcgcc tgctgcgtga
    21841 gcggatggcg ggtctgggct ggctggtccc ggacatcctc gcgcacctgg acgacacccc
    21901 ggacttctac ctcgaccagg tcgcccaggt ggtgatggac cgctggtcga gcggccgggt
    21961 ggcgctgctc ggggacgcgg cattcagctc gtcgcccatg tccggccagg gcaccgggtt
    22021 ggcgctggtc ggcgcctacg tgctggccgg ggagctggcc gccgccgact gggatcccga
    22081 ggcggggttc gcccgctacg aggcgcggat gcgctcgttc gtcgaggcca accaggagat
    22141 cggccgtatg aacgcccgca gccgcgacgt cccgggggcg gacgccgaac cgcagcccga
    22201 tttcaccagc gcatggttca ccgatctggt cgggcgcgcg atcaacggcg tcgagctgcc
    22261 ggaatacggg gggttgcctg actccgcgac ctcggccgga tcgccgatcc cctcctcgaa
    22321 caagccgtag gcatcccgca tcccacgtgc cgagaggggc cgccctccag tgggccccgc
    22381 tcggcgacat tgcgccgatg agctgacctc cggtccccca cggtgcagac aggatccaac
    22441 cgccctcccc gaccacaagc ccggcaccgc acccaaccac cccaaggaca ctgccgagtt
    22501 gaaactgcac accacgatct gctccgacac gacgtaactc acggcagcgc agagcgccgt
    22561 cgccacagac caccgacgcc gcctcaaggg cacgtcagag ccgaccgagg tcaaacgccg
    22621 aggatgtgac gcagctcttc agcacgcccc ggcggaccac agcgcggtta ctgaggttga
    22681 actcgtggtg tcgtgtcgtt gctcaggtgg gtctgatgct caggccggtc tcggcgaggc
    22741 agccgtcgat gagctcgctg cggtactgga tgtgccgtaa g
//
