LOCUS       NZ_CP032543            41134 bp    DNA     linear   CON 15-NOV-2023
DEFINITION  Streptomyces griseus subsp. griseus strain ATCC 13273 chromosome,
            complete genome.
ACCESSION   NZ_CP032543
VERSION     NZ_CP032543.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces griseus subsp. griseus
  ORGANISM  Streptomyces griseus subsp. griseus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7238194)
  AUTHORS   Liu,J., Yu,B., Liu,X. and Shen,C.
  TITLE     Complete genome sequence of Streptomyces griseus ATCC 13273
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7238194)
  AUTHORS   Liu,J., Yu,B., Liu,X. and Shen,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2018) Jiangsu Key Laboratory of Tcm Evaluation and
            Translational Research, China Pharmaceutical University, Longmian
            Avenue, Nanjing, Jiangsu 211198, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JAN-2016
            Assembly Method                   :: SMRT analysis v. 2.3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 88.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/15/2023 05:04:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,408
            CDSs (total)                      :: 6,322
            Genes (coding)                    :: 5,933
            CDSs (with protein)               :: 5,933
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 389
            CDSs (without protein)            :: 389
            Pseudo Genes (ambiguous residues) :: 0 of 389
            Pseudo Genes (frameshifted)       :: 299 of 389
            Pseudo Genes (incomplete)         :: 144 of 389
            Pseudo Genes (internal stop)      :: 16 of 389
            Pseudo Genes (multiple problems)  :: 65 of 389
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:22:13
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 369922
            Orig. end                         :: 411056
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP032543.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from China pharmaceutical
            University, Jiangsu Key Laboratory of TCM Evaluation and
            Translational Research.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41134
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="5"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41134
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41134
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21134](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21134)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     misc_feature    complement(702..717)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.33"
                     /tool="antismash"
     misc_feature    1629..1644
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    complement(1629..1646)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.84"
                     /tool="antismash"
     gene            complement(1697..2953)
                     /locus_tag="D6270_RS01630"
     CDS             complement(1697..2953)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (85-414). E-value:
                     2.4e-53. Score: 173.5. Matches aSDomain:
                     nrpspksdomains_D6270_RS01630_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606875.1"
                     /locus_tag="D6270_RS01630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_109167116.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-51, bitscore:
                     174.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="t2fas (E-value: 4.3e-129, bitscore: 429.4,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQSADQGTGAATGTAIAVTGVGLVTPAGADEHSFWEGLCSGHST
                     ARRRPELAGLPVDFACAVDSIDLDEAVGGRSVWRMARFVKLAVVAARQAVADAGLDPAV
                     WDGGRVGVVLGVGVGGVSVLVDNAARLAASGPEAVSPLLVPMMIPNAAAGEVAIALKAG
                     GPSLAPATACASGATAIAVARDLLLGGGCDVVVAGGAESVLTPLVVTAFARMGALSTRT
                     ADPAGASRPFADDRDGFVIGEGAAMLVLEREEAARARGGRARALLTGAGSSTDAHHPTA
                     PAPDGRGAQRAVQAALDQAGWAPGEVDHINAHGTSTPLNDAMETTLISRLFPHRPPVTA
                     PKGVLGHTLAAAGAIEAVATVLTLERSLIPPIANLDSLPDAFPLDCVVKEPRHQRVERA
                     VSHSFGFGGHNVALAFQRT"
     aSDomain        complement(1712..2698)
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D6270_RS01630_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.40E-53"
                     /label="D6270_RS01630_PKS_KS.1"
                     /locus_tag="D6270_RS01630"
                     /protein_end="414"
                     /protein_start="85"
                     /score="173.5"
                     /tool="antismash"
                     /translation="LAVVAARQAVADAGLDPAVWDGGRVGVVLGVGVGGVSVLVDNAAR
                     LAASGPEAVSPLLVPMMIPNAAAGEVAIALKAGGPSLAPATACASGATAIAVARDLLLG
                     GGCDVVVAGGAESVLTPLVVTAFARMGALSTRTADPAGASRPFADDRDGFVIGEGAAML
                     VLEREEAARARGGRARALLTGAGSSTDAHHPTAPAPDGRGAQRAVQAALDQAGWAPGEV
                     DHINAHGTSTPLNDAMETTLISRLFPHRPPVTAPKGVLGHTLAAAGAIEAVATVLTLER
                     SLIPPIANLDSLPDAFPLDCVVKEPRHQRVERAVSHSFGFGGHNVALA"
     CDS_motif       complement(2417..2464)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_D6270_RS01630_0001"
                     /evalue="2.40E-02"
                     /label="PKSI-KS_m3"
                     /locus_tag="D6270_RS01630"
                     /protein_end="179"
                     /protein_start="163"
                     /score="7.7"
                     /tool="antismash"
                     /translation="GPSLAPATACASGATA"
     gene            complement(2937..3971)
                     /locus_tag="D6270_RS01635"
     CDS             complement(2937..3971)
                     /EC_number="2.3.1.180"
                     /GO_function="GO:0004315 - 3-oxoacyl-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514914.1"
                     /locus_tag="D6270_RS01635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="beta-ketoacyl-ACP synthase 3"
                     /protein_id="WP_109167115.1"
                     /sec_met_domain="fabH (E-value: 2.5e-90, bitscore: 301.4,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLESVAGWVPGEPVPNDQLPADWGVDDAWVRRRTGIGGRHRAGPG
                     VATGDLAYEAASRLLAGSPAAGPVEAVVLATATPDHLCPGTAPALAARLGLGTVPALDI
                     AAVCSGFVYGLALSHGLIASGLYGRILLVGADVYSTWLDPDDRSAGVVFGDGAGAALVA
                     AGRTGDPGELLAFDLGSDGTGDGLITVPGGGARARADGKPPALSDAYFRMQGQTVYQHA
                     VERMTGSCRVLLERVGWDPAEVDHFVPHQANARILRAVADRVGIAPQRCVTHLERVGNT
                     GAASIPLALADAAGRGLLQGGDRVLLTAFGGGLTWGSAALRWPGTPQTISTDSTEGTQH
                     VAVR"
     misc_feature    4073..4087
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.63"
                     /tool="antismash"
     gene            complement(4160..5116)
                     /locus_tag="D6270_RS01640"
     CDS             complement(4160..5116)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1276: PfkB domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491346.1"
                     /locus_tag="D6270_RS01640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate kinase"
                     /protein_id="WP_109167114.1"
                     /transl_table=11
                     /translation="MLDHSELLVVGECVADIVRQPDQDDRAHPGGSPANVAYGLARLGH
                     RATLLTQLGADPNGQLIRDHLASAGVTVRTDGSTTATPSAVVTLDGAGQASYAFDIAWT
                     LAPVAVGPAPGHVHTGSIGAVVEPGAATVLDIVRAARTTATVSYDPNVRPALMGDHAAA
                     VARVEACVALSDLVKASDEDLAWLYPGEEPERVAVRWLEQGPAAVLVTRGGDGALAVLP
                     GGRITVGAATVEVVDTVGAGDAFMSGTLHALAAHGLLGAGARERLHAVDRDTLTDVLRH
                     AVAAAAVTVSRAGANPPDAAELREALGREGAQGGARP"
     misc_feature    5218..5233
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            complement(5230..6588)
                     /locus_tag="D6270_RS01645"
     CDS             complement(5230..6588)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514912.1"
                     /locus_tag="D6270_RS01645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_109167626.1"
                     /transl_table=11
                     /translation="MPRPPAPTGRGLDPLTARRRFTTVSFLFWLPVGMSVATGVLLFTD
                     RSMGLAAIAGFFAVHSLTAAAMELPTGGLSDVIGRRAVLATAGLLNCTAFTLFGLAGAA
                     WAITLGMALMGCARALSSGPAEAWYVDTVHAHAGPDADLRTGLARGSSAMSAALALGTL
                     LGGGLPWLLGPGIGVGEWLTGTTGGLVIPLSVPALLGALVEIVFVLYVLSALPEPPRPP
                     ATLRGVVGGVPAAIGAGLRLGARDALIRRILLTASAAGAALAAVELLTPGRAAALMGTA
                     ESGALLFAGLACAGFLCSALGSQLAPLAARLTRSSERAVLSGGGVVALGLILLGVTTGA
                     TSPLATTAAVTGYGLVYLGLGVVGPNTNDLLHRRVDASGRATALSVQSLALQLVAAGAG
                     LAAGALPLGPLPWLLAAAVVLAVALLWARRVAVSPQVSVPSAQPVPAVSAPER"
     gene            complement(6630..7244)
                     /locus_tag="D6270_RS01650"
     CDS             complement(6630..7244)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514911.1"
                     /locus_tag="D6270_RS01650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_109167113.1"
                     /transl_table=11
                     /translation="MDSEPTRRVLDPGRDGAALKALTHPLRIELLGLLRRHGPATASEL
                     AARTGESSASTSYHLRVLAKYAFVAEADHRDSRERRWKAVHTLTSWSNEAMHRAPGGRA
                     ALSTLRRRQLEHLERSLARHEDDLENGRLDTAWQEPSGLSDSLPRLTPESLTELWETVA
                     TKMAELTARDADDPRAEQVVVVTAGLPLAPEPAPDAEGPAS"
     misc_feature    complement(7282..7295)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.12"
                     /tool="antismash"
     misc_feature    7283..7296
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.5"
                     /tool="antismash"
     misc_feature    complement(7284..7297)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.92"
                     /tool="antismash"
     misc_feature    7284..7298
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.21"
                     /tool="antismash"
     misc_feature    7295..7304
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     misc_feature    complement(7295..7309)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.49"
                     /tool="antismash"
     misc_feature    7296..7310
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.21"
                     /tool="antismash"
     gene            complement(7329..7886)
                     /locus_tag="D6270_RS01655"
     CDS             complement(7329..7886)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514910.1"
                     /locus_tag="D6270_RS01655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_109167112.1"
                     /transl_table=11
                     /translation="MALRHAVLAALLDEELSGYELAKAFDMGVANFWHALPQQLYAELA
                     KLEKEGLVAGREVVQDTRPNKRLFRVTDGGLAELERFAAVAAKPSFIRDDLLVKVQAAD
                     HLDPGELIARLAERAEFAGAKAAQFEALLKGMRGERAEEEFLRYGERIGPYLTCRRGLD
                     FERANRDWCREVIEVLRARSAG"
     misc_feature    complement(7941..7954)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.09"
                     /tool="antismash"
     misc_feature    complement(7960..7973)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.49"
                     /tool="antismash"
     misc_feature    7964..7977
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.79"
                     /tool="antismash"
     gene            8014..8439
                     /locus_tag="D6270_RS01660"
     CDS             8014..8439
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF07366"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514909.1"
                     /locus_tag="D6270_RS01660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_109167111.1"
                     /sec_met_domain="PF07366 (E-value: 3.9e-05, bitscore: 22.0,
                     seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAVDRFRTAVDTRDLSALDDLFTEDVRFYSPVKFTPFEGRPMV
                     LGLFGVLLRTFEDFRYVGEFGGTAQTSVDGAEAPAAVLLFRATVNGKEIHGIDLVHLAE
                     DGRIKEFTVMVRPQSAVHALGEAVLAGLVADGLVPTE"
     gene            complement(8345..9304)
                     /locus_tag="D6270_RS01665"
     CDS             complement(8345..9304)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D6270_RS01665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_318780015.1"
                     /transl_table=11
                     /translation="MTEQSEWRFSDDRGQLSTAPRRPERVLAYVQAGATLWGLGIRPQG
                     IFGSDHDGPEPDREKTGTLPLDEVAYVGAGSGLDVERLLSGGTDLVVAVSYGNGHVYGL
                     APETAKQLEERVPVVVLDVSQARTFEEIGDRFAELARSLGAGGRADADADLDAARERLR
                     AVAAAGAADPPRVLALSPAGPDQAHVARPGMWPELRVLTELGVHLVEPAPGPGANWSTL
                     DRAGTFALRPDVILADIRAHAAPPTSWAGTAGSRSCRGTRSPCTAPATTPASSAWSRTR
                     WRDSRERATPSGPVRRPPARRGPPRRARARRTGAGPSR"
     gene            9530..10375
                     /locus_tag="D6270_RS01670"
     CDS             9530..10375
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970945.1"
                     /locus_tag="D6270_RS01670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M12 family metallo-peptidase"
                     /protein_id="WP_109167109.1"
                     /transl_table=11
                     /translation="MRAPLLKVTLAAGLAASLCAAPFLTDTSASAPAAPAPASGAVRCP
                     VVDVLVVHTPKAAERLGGQHRVPASAQRIATRMNRSLAADGLCGTIRIVHPYTAKEYDG
                     SEEFRAAYAVLKDHTSGLGRQVHEQRERYGADLVTLVVERAERGGGTADYTSALDSSTH
                     EYAYSVVEVDGIELDSASHEIGHNLGLAHDRTTLASDTGGSMNVSRTRPYNTGWITEDG
                     QHYTLMAYRASCGTHCKRISRFSSAKGSWRGHRLGDESNDSVRVLRETMPIVAGYRSKT
                     "
     gene            10441..11451
                     /locus_tag="D6270_RS01675"
     CDS             10441..11451
                     /NRPS_PKS="Domain: PKS_ER (14-323). E-value: 1.3e-26.
                     Score: 85.4. Matches aSDomain:
                     nrpspksdomains_D6270_RS01675_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763220.1"
                     /locus_tag="D6270_RS01675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_109167625.1"
                     /sec_met_domain="ADH_N (E-value: 1.8e-16, bitscore: 58.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.8e-21, bitscore:
                     74.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRMRAVRLHLPTRTLSVEEVAKPVPGPGEVLVKVAAAGVCLSDV
                     HLVDGTLTPVYPAGDSVTLGHEVAGTVDALGPGVEGWTAGQRVVLQAGERRGGRTHTRG
                     VDYDGGWAEYALASAATLVALPPTLPLDQAAIIPDAVSTPWAAVTVTGEVRPAQAVAVW
                     GAGGLGAHAVQLLRAVGACPVIAVDPAPAARDRALHFGADLALDSGDPLLREQVLGATG
                     GAGLEAAFDFAGVPAVREQALGVLAPKGRLVLVGLNDQPLTVAHSTRFSYLQHRILGHY
                     GSEEHHVAQLVRLAEGGRLDFSRSITGVLPLEEAATAVRRMETKEGDPVRLILRP"
     aSDomain        10483..11409
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D6270_RS01675_PKS_ER.1"
                     /evalue="1.30E-26"
                     /label="D6270_RS01675_PKS_ER.1"
                     /locus_tag="D6270_RS01675"
                     /protein_end="323"
                     /protein_start="14"
                     /score="85.4"
                     /tool="antismash"
                     /translation="TLSVEEVAKPVPGPGEVLVKVAAAGVCLSDVHLVDGTLTPVYPAG
                     DSVTLGHEVAGTVDALGPGVEGWTAGQRVVLQAGERRGGRTHTRGVDYDGGWAEYALAS
                     AATLVALPPTLPLDQAAIIPDAVSTPWAAVTVTGEVRPAQAVAVWGAGGLGAHAVQLLR
                     AVGACPVIAVDPAPAARDRALHFGADLALDSGDPLLREQVLGATGGAGLEAAFDFAGVP
                     AVREQALGVLAPKGRLVLVGLNDQPLTVAHSTRFSYLQHRILGHYGSEEHHVAQLVRLA
                     EGGRLDFSRSITGVLPLEEAATAVRRME"
     gene            complement(11435..12409)
                     /locus_tag="D6270_RS01680"
     CDS             complement(11435..12409)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514905.1"
                     /locus_tag="D6270_RS01680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_109167108.1"
                     /transl_table=11
                     /translation="MPTQTAAAAERTATGRPRAPRHWLTALRRTPVSLWNDDITDWAAA
                     LTYYAILALLPALLVTVSVIGLANPGATTALIADITAFAPAESGEALRRPLEAATEKRS
                     AVWLLVATGSVSAVWSACSYLAVFRRAMHAMHGVRDNRPPLRQAHIIVLSAIGLLVLLM
                     TSAFALVMTGPLARWLGGRVGLPHEGQTLWVVLKWPVLLCLVACLILVLFSTGPRSARG
                     VRRGLPGGVLAAFLWLTASALFALYATQVGSYSRLYGSLAGLVVFLIWVWFANLSLLAG
                     AQFNVELDRREPAKVPKPKPEPKPEPEPEPKPEPKEDPATAAG"
     gene            complement(12575..12892)
                     /locus_tag="D6270_RS01685"
     CDS             complement(12575..12892)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970941.1"
                     /locus_tag="D6270_RS01685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cupin"
                     /protein_id="WP_109167107.1"
                     /transl_table=11
                     /translation="MDDLNALAEEHLAAARTSAHGRSAHLLIQEPPLRQTVIALTSGSA
                     LDEHNAPPAASLLVLRGTVRLTAGSGDADLPAGTLHPIPQERHGLLALQDAVVLLTAVN
                     D"
     gene            complement(13064..14071)
                     /locus_tag="D6270_RS01690"
     CDS             complement(13064..14071)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606887.1"
                     /locus_tag="D6270_RS01690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_109167106.1"
                     /transl_table=11
                     /translation="MTRRLAQVAKKVGVSEATVSRVLNGKPGVSRTTRQSVLTALDVLG
                     YERPTQLRGERARLVGLVLPELQNPIFPAFAEVIGGALAQQGLTPVLCTQTKGGVSEAD
                     YVDLLLQQQVSGVVFAGGLFAQADEAHEHYHRLAERRIPVVLINAPIEGLDFPCVSCDD
                     AVAIERAWRHLASLGHERIGVVIGPSDHVPSRRKLAAARSVASATGGQLPEENIERSMF
                     SLEGGQAAASRLLERGITGIICASDPLALGAVRAARRRGLGVPSDVSVVGFDDSAFMSC
                     TEPPLTTIRQPIEAMGRAAVELLCAGIQGGAVPPGELLFEPELVVRGSTAKAPR"
     gene            complement(14192..18481)
                     /locus_tag="D6270_RS01695"
     CDS             complement(14192..18481)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970939.1"
                     /locus_tag="D6270_RS01695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="discoidin domain-containing protein"
                     /protein_id="WP_151414648.1"
                     /transl_table=11
                     /translation="MRAQRWRWRAISALVTTSLLMIGWPSLTASAADGPNLAAGRAATA
                     SSAHAEYPAPNITDGNASTYWESAGGNLPQWVQTDLGSSARVDEVTLKLPPSWESRTQT
                     LSLQGSADGTSFATLKGSAAYSFSPGSANTVKVEFPATLTRFVRVNITANTGWQAAQLS
                     ELEVRAAAESSGNLAAGKTLKASSGNGSYVAANANDGNRASYWASRENAFPQWIEADLG
                     SSVRVDRVVLRLPDGWAARSQTLKLQASTNGAEFTDLTASKEYRFDAAGGQSATISFDP
                     TTTRYVRVLVTANSGSPSAQLAELEVYGPATGDTQAPTAPADLAFTEPATGQIRLTWKA
                     ATDNTGVTGYDIYANNTLLATVAGNVTTYTDTRPAGQTVSYYVRAKDAAGNVSSNSNTV
                     TRTGDTGDTQAPTAPTALAFTEPAAGQIRLTWQASTDNKGVTGYDVYANNVLRGSVAGN
                     VLTYTDTQPATATVSYFVRAKDAAGNVSTDSNTVTRNGSTGAASNLAVNKPITASSVVH
                     TFVAANANDNSTATYWEGAGGSYPNTLTVQLGSNADTQSVVVKLNPDSSWGPRTQRIEV
                     LGREQSSSSFNSLVAAKDYAFSPASGNTVTIPVSARIADVQLKFTANSGSGAGQVAEFQ
                     VLGAPAANPDLQVTGITASPATPVESDTITLTATVRNAGALAAPASKVEFRLGGSKVAT
                     GSVGALAAGASTQVSAAIGARGAGSYVLSAVADPENEVIEQNETNNTYTAASPLVVQPV
                     SSSDLVATSVTTSPSAPSAGNTVTFSVAIKNQGTIASASGSHGITLTLLNSQGATVKTF
                     TGAHTGTIAAGATTAPVSLGTWTAVNGSYTLRTVLAADANELPVKRENNTSTESLFVGR
                     GANMPYAMYEAEDGTTGGGAQVVGPNRTVGDIAGEASGRKAVTLNNSGNYVEFTTRAAT
                     NTLVTRFSIPDSAGGGGINSTLNLYVDGTFLKAIDLTSKYAWLYGNEAAPGNSPGSGAP
                     RHIYDEANVMLGKTVPAGAKIRLQKDAANSTTYAIDFISLEQVAPVANPNPAAYTMPTG
                     FTHQDVQNALDRVRMDTTGNLVGVYLPPGEYSTASKFQVYGKAVKVVGAGPWYTRFNAP
                     STQDNTDIGFRAEASAKGSSFANFAYFGNYTSRIDGPGKVFDFANVSDIVIDNIWNEHM
                     VCLYWGANTDSITIKNSRIRNMFADGINMTNGSTDNLVTNIEARATGDDSFALFSAIDA
                     GGADMKNNLYENLTSILTWRAAGVAVYGGYDNTFRNIHIADTLVYSGITVSSLDFGYPM
                     NGFGTQPTKIENVSIVRSGGHFWGSQTFPGIWLFSASKVFQGIRISNVDIVDPTYSGIM
                     FQTNYVGGQPQFPIKDTVLTDVSISGARKSGDAFDAKSGFGLWANEMPEAGQGPAVGEV
                     TFNRLRLSNNAQDIRNTTSTFKININP"
     misc_feature    complement(18599..18613)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.78"
                     /tool="antismash"
     misc_feature    18667..18681
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            complement(18712..19902)
                     /locus_tag="D6270_RS01700"
     CDS             complement(18712..19902)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382078.1"
                     /locus_tag="D6270_RS01700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S8 family peptidase"
                     /protein_id="WP_109167105.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 5.7e-39, bitscore:
                     132.7, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLRARWAPAALLLIAPLIGTTTPATADTGPEGVPVERSARAVPG
                     QYIVTLEPELSPDTVLEEFGLRPLFTYGNVLHGFAVTLTATELEAVRAVPGVLAVEENA
                     EVAVEAPRTGGLFRAPAATWGTDRIDQRALPLDDTFTTTATGEGVKVYVVDTGIDAAHA
                     EFGSRVVKGYDAVGDGRDGQDCNGHGTHVAGTVAGSTSGVAKDASLVGVRVLNCQGRGT
                     WAGIIAGFDWVAKDAAAGSTPAVLNASLGGARSRAVDAAVEAVADAGVLPVVAAGNEDQ
                     DACDVSPAAADGVVTVGASDRQDRETSFSNWGSCLSLYAPGADIVSAKLGGGTVSLNGT
                     SMASPHVAGVAALYKEENPSATPAAVTRWLTDTATPKVLSGLGQGSPDLLLYTGGL"
     misc_feature    19892..19905
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.54"
                     /tool="antismash"
     misc_feature    19956..19970
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.43"
                     /tool="antismash"
     gene            complement(20001..21134)
                     /locus_tag="D6270_RS01705"
     CDS             complement(20001..21134)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010061723.1"
                     /locus_tag="D6270_RS01705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type III polyketide synthase"
                     /protein_id="WP_225977023.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.9e-17,
                     bitscore: 62.0, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 3e-18, bitscore:
                     64.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGEPMATLCRPAIAVPEHVITMQQTLELARETHHGHPQRDLVLR
                     LIRNTGVQTRHLVQPIEETLRHPGFELRNQVYEAEAKTRVPEVVRQALANAGTDPDDID
                     LIVYVSCTGFMMPSLTAWLINTMGFRPGTRQLPIAQLGCAAGGAAINRAHDFCRAYPDS
                     NVLIVSCEFCSLCYQPTDIGVGSLLSNGLFGDAISAAVVRGQGGTGMKLERNGSHLVPD
                     TEDWISYAVRDTGFHFLLDKRVPGTMEMLAPVLQDLVDLHGWSVPDMDFFIVHAGGPRI
                     LDDLCHFLNLPMEMFRYSRATLTERGNIASSVVFDALARLFDDGGAAESAQGLIAGFGP
                     GITAEVAVGSWANHDPGTDPDRELAELERAAGVALSG"
     gene            complement(21154..22389)
                     /locus_tag="D6270_RS01710"
     CDS             complement(21154..22389)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970936.1"
                     /locus_tag="D6270_RS01710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_109167624.1"
                     /sec_met_domain="p450 (E-value: 7.1e-27, bitscore: 92.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDASTHDPSVHDKETVRSCPFDFAQQLEFDPQLKELLTEEPVSR
                     IRMAYGEGEAWLVTRYEDVRTVTTDRRFSRSAVLGRDFPRMTPEPIVQAESINLMDPPA
                     SSRLRSLVAKSFTPRRVEQMREGTQRVVDRLLDGMEDEGSPADFVARVSSPLPLITICE
                     ALDIPEADRPWLRAHAMTMMNVGAAGKEDAVRAKAELRGYFTELTAERRRSPGQDLIST
                     LATARDGDELLDDRELAVMAMVLLITGQDTTTYQLGNIAYTLLTRPQLLKTLQAEPERL
                     PRTLEELLRYIPFRKGVGIPRIALEDVELGGVAIKAGDVVHVSYLTANRDAAKFDRPDE
                     LDPARPSIPHMTFGWGAHHCLGAPLATMELEVAFSTLLARFPALRLDAEPEDIRWNTTS
                     IWRYPLALPVTW"
     gene            complement(22555..23361)
                     /locus_tag="D6270_RS01715"
     CDS             complement(22555..23361)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544092.1"
                     /locus_tag="D6270_RS01715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_109167103.1"
                     /transl_table=11
                     /translation="MTTDHQLTAEHLTLGYGDRTVVSSLDLVVPPGRITVVVGANACGK
                     STLLRSMSRLLAPREGRVVLDGKEVHRLPAKELARTLGLLPQSPVAPEGITVSDLVGRG
                     RHPHQSMFSRWNEKDDAAVASALEATATEPLADRAVDELSGGQRQRVWIAMALAQQTDL
                     LLLDEPTTFLDASHQIEVLDLLTDLNRSRGTTIVMVLHDLNLAARYADHLIALADGTLH
                     AVGAPAEVLTEETVRAVFGLDSRVIEDPVSGRPLMLPIGRHHVLAG"
     gene            complement(23358..24431)
                     /locus_tag="D6270_RS01720"
     CDS             complement(23358..24431)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951900.1"
                     /locus_tag="D6270_RS01720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_109167102.1"
                     /transl_table=11
                     /translation="MSAPALTRPAPKEAYPASVAAATRRRIRGASRRRLVILVLAALVV
                     TAFAVTLMAGRTFYPPGDVFRVILGEQVPGATFTVGRLRLPRAVLALVAGFSFGLAGVT
                     FQTMLRNPLASPDIIGISSGASAAAAIAIVTLSLGEVQVSALAIAAGLGVALLVYSLAF
                     RGGVVGTRLILIGIGISAMLDSVTSYVLSQAAEWDLQEAMRWLTGSLNGATWDQVVPVL
                     AAAAVLTPLLLGQARSLSAMQLGDDTASALGVRVERTRITVIVAAVGLIAFATAAAGPI
                     AFVAFLSGPIAARIVGAGGSLLVPAGLVGSLLVLVADFTGQFAFGERYPVGVVTGVLGA
                     PYLVYLIIRTNRAGGSL"
     gene            complement(24428..25471)
                     /locus_tag="D6270_RS01725"
     CDS             complement(24428..25471)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006826 - iron ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469014.1"
                     /locus_tag="D6270_RS01725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron ABC transporter permease"
                     /protein_id="WP_109167101.1"
                     /transl_table=11
                     /translation="MTAVTDRRPPDASMARRPAGVRTLWLLAAVLLLAAVMVASVAFGS
                     RDVPWADVQAALGGADETLGQAAATKRIPRTVLAVVIGAALGLAGGVMQGVTRNPLADP
                     GILGVNMGASLAVVTAVAFFGLSSPTGYIWVAIAGAALSALFVYTVGTLGRGGATPLKL
                     ALAGAATSAAFASLVSAVILPRNDIAGSFKLWQIGGVGGASFERIGQVAPFLAVGFAIC
                     LLSARALNSLALGDELAAGLGERVAVARAVAALGAVLLCGAATAVAGPIGFVGLVVPHT
                     CRLLVGVDHRWLLPLSALLGAVLLTAADVAGRIVARPAEIDVGIVTALIGAPFFIYIVR
                     RQKVRAL"
     gene            complement(25468..26508)
                     /locus_tag="D6270_RS01730"
     CDS             complement(25468..26508)
                     /GO_process="GO:0015891 - siderophore transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003951902.1"
                     /locus_tag="D6270_RS01730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="WP_109167100.1"
                     /sec_met_domain="PP-binding_2 (E-value: 0.12, bitscore:
                     11.2, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSHRLRLLAVAAALVSVAACGGNGNGDAGNKKGEGSAAGGFPLT
                     VEHALGKTTIPAKPKRVATVNWANHEVPLALGVVPVGMAAANFGDDDGNGVLPWVEERL
                     TELKAKTPVLFDETDGIDFEAVADTKPDVILAAYSGLTKKDYDTLSEIAPVVAYPDAAW
                     ATPWREIIRTNSEAIGLADEGEKLITKLDGDIAKTAAKYPQLKGKSAMFMTHVDPNDVS
                     EIGFYTTHDTRTQFFEDLGMTTPGSIAKASEGTKKFALTKSAEQIDAFDDVDIITGYGD
                     DTGDLLKAITKDPLLSKIPAVKRSSTYLLPGSSPLATAANPTPLSIGYVLDDYAAALAK
                     AADKVK"
     misc_feature    26606..26624
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 29.62"
                     /tool="antismash"
     misc_feature    complement(26654..26667)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.62"
                     /tool="antismash"
     gene            complement(26734..27507)
                     /locus_tag="D6270_RS01735"
     CDS             complement(26734..27507)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606896.1"
                     /locus_tag="D6270_RS01735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_109167099.1"
                     /transl_table=11
                     /translation="MTRETRSLPAHAPGSVDTPFVIQPYDEVVSHDTLWDAHSHPFHEL
                     LWNERGASSAVVGERIWTITPALGLWMPAGTLHSGSATAGTWFRASFFGFRTTSSISDT
                     PVAVEITPLLRLLLERLGEPGLAPSSRSATEALVLDVLAPSPRELLVQIPTSDLLRPVA
                     DAVREDPGDQRTLAEWAAELEVSTRTITRAFSAETGTSFVRWVAAVRAQRAIDLLTRGW
                     DVESVAEQVGYRSASAFGVAFRRTTGLTPGSFRAG"
     gene            28369..28902
                     /locus_tag="D6270_RS01745"
     CDS             28369..28902
                     /GO_function="GO:0005509 - calcium ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491365.1"
                     /locus_tag="D6270_RS01745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_109167097.1"
                     /transl_table=11
                     /translation="MTTEATRRVALVFSLFDANANGVLEADDFDLMAERVVRQAHASDQ
                     AAKDAMRAAFRRYWTTLLTELDADGDGEISFEEFTACVLSPERFDATVAVFAEALAALG
                     DPDGDGLIERPLFMALMTAIGFEPANIDALFDAFEPADGDRIRVETWVAGIKDYYAPGK
                     AGIPGDHLVVGTPV"
     gene            complement(28979..29395)
                     /locus_tag="D6270_RS01750"
     CDS             complement(28979..29395)
                     /EC_number="3.1.2.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491366.1"
                     /locus_tag="D6270_RS01750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="thioesterase family protein"
                     /protein_id="WP_109167096.1"
                     /sec_met_domain="4HBT_2 (E-value: 4.2e-22, bitscore: 77.4,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFSVDVTVRGYELDTQGHLNQAVYLQYAEHARWELLRAAGLPQE
                     KLLADGIGPVQLEVTVKYLRELRGGERVRVTCRFEYGSGKTFTLEQQVVMEDGSVAAEI
                     TGVAGVLDLAERRLVPDPQGRLAALAGDPDLLTG"
     gene            29593..32616
                     /locus_tag="D6270_RS01755"
     CDS             29593..32616
                     /GO_function="GO:2001070 - starch binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382069.1"
                     /locus_tag="D6270_RS01755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="WP_109167095.1"
                     /sec_met_domain="Alpha-amylase (E-value: 3.6e-38, bitscore:
                     130.4, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRTPHRLSGRPLAAALAAGLLGLLTSVPQAAPAPAGTPVAATAA
                     AEATATVFYSTKTRNWSAYHLHYALDGGSWTTVPGSRMQSACTDWVKFTVPLGGASGLR
                     AAFNNGSGTWDNNAGRDYDLGTGNITVKDGVVAHSDPCAGTGPEEPDPGGPNTASVYYA
                     TSTVGWSTVNLHYRPHGGAWTAVPGVGMEAACAGWVKRTVDLGGATGLQAAFNNGNGVW
                     DNNNGGDYTLPAGLTIVQDRKVTATAKDPCAAEEPDTEAPSVPTGARAAADGVSVLVTW
                     EPATDNRGVTKYQVTRTGGTKGTLVTDAGSTVLADTGLEARTAYRYTVRAVDAAGNVSA
                     ESAPATATTGEKPTAPATGTPLGTDPRKDPIYFVLTARFNDGDATNNRGGSQHEKSGNA
                     AGDDPMFRGDFKGLVQKLDYVKGLGFSAIWITPVVLNRSDYDYHGYHGYDFYRVDPRLE
                     SAGASYQDLINAAHAKGMKIYQDIVHNHSSRWGAKGLFTPTAYGVRDSQWSRYYDERND
                     GFAYDGLTVEPKSGKSYYNGDLWSTAEPSGNTCVGWGTPTGQTSPEGYRIYNCQWPSPT
                     SGMFPKALYHNCWIGNWEGEDSRSCWLHDDLADLNTENAQVQNYLIGAYNKYIDMGVDG
                     FRLDTAVHIPRTTWNRRFLPAIQERVTQRFGAEAARNFFVFGEVAAFVNDKWNRGSVNH
                     SAQFFTWKERKEYSADDEKAALEMYGYEQQQGTAAQPVSDNAFLRGNAYHAPDRSRFSG
                     MNVIDMRMHMNFGDADNAFHNGKDSDDSYHDATYNVVYVDSHDYGPNKSSERYAGGTDA
                     WAENMSLMWTFRGIPTLYYGSEIEFQKGKRIDCGPTCPLASTGRAYFGDRLAGEVTASD
                     FGKVASATGKVADTLAAPLARHLQRLNEIRRAIPALQMGQYATEGISGSMAYKRRYTDT
                     ASGTDSFALVTVSGSATYTGIPNGTYQDAVTGDTKVVSGGTLAVPAPGKGNLRVYVLDL
                     GGKNAAPGKIGAAGPYLK"
     gene            complement(32622..32789)
                     /locus_tag="D6270_RS32420"
     CDS             complement(32622..32789)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D6270_RS32420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158650470.1"
                     /transl_table=11
                     /translation="MTTPLPGATRAEGVLESASDGHRPVTGPTPDRPRTDHDPPDRREY
                     LLRTVRRVAG"
     gene            complement(32798..33892)
                     /locus_tag="D6270_RS01760"
     CDS             complement(32798..33892)
                     /EC_number="5.1.3.-"
                     /GO_function="GO:0016857 - racemase and epimerase activity,
                     acting on carbohydrates and derivatives [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514887.1"
                     /locus_tag="D6270_RS01760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldose epimerase family protein"
                     /protein_id="WP_109167094.1"
                     /transl_table=11
                     /translation="MPTVHRKPFGRAHGKSDTDLWTLDSGTGVRAGILTYGGVLHSLTV
                     PDTDGAPGPVVRSLPALDDYTDKNPYFGAIVGRYANRIAHGRFTLDGTTHHIPANDRGH
                     ALHGGPDGFHTKVWQATADRTDSAAVLRLTLHSPDGDMGFPGALDVTATYTLDTTGTLA
                     LEYTAVTDRPTVVNLTNHAYLNLGADDILGHTLQVDADDYLPVDAGSIPEGPPAPVTGT
                     PFDLTTAQPIRNALSRPHPQLALAGGFDHCWVLREAAPGTLRRAARLTAPGDRRTLELW
                     TTEPGLQVYTANQLDSAFTDGTGRRHERHGSLCLETQHLPDSPNHPAHPSTVLRPGETL
                     RSRTEWRFPHLHGKGNRLRPSTTA"
     gene            complement(33921..34940)
                     /locus_tag="D6270_RS01765"
     CDS             complement(33921..34940)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514886.1"
                     /locus_tag="D6270_RS01765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_109167093.1"
                     /transl_table=11
                     /translation="MGVSLKDVAQRAGVSIKTVSNVVNNYQHVTPKMRAKVQQAIDELG
                     YRPNLTARHLRKGRTGIIALAVPEFGNPYFAELAGEVVDAAARHDYTVLVDHTGGLREK
                     ELLVSQGFRSHVIDGLILSPIHLETEDLMARTETAPLVLLGEREYEAPYDHIAIDNVAA
                     AREAVAHLIAHGHRRIAFLGSRTGQERQPAHLRLRGWREELAASGITPDESLVVVTDGY
                     GREDGAAAMASLLDRGERPDAVFAYNDMIAIGAMRTITERGLTIPGDIAVVGFDDIEES
                     RYGSTTLTTIAPDKAAIARLAVDSLVERLAGTPVAEPRRPRPGYRLVLRESTGPRHSR"
     gene            complement(34998..36044)
                     /locus_tag="D6270_RS01770"
     CDS             complement(34998..36044)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606907.1"
                     /locus_tag="D6270_RS01770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_109167092.1"
                     /transl_table=11
                     /translation="MKNTTPAALAPQVPAPLKNTPSRPEPRPERSTGSRIGELVQRQGV
                     LAVLLTVILIASFVYPTFASVDNARGVTVQASFLAIVALGMTLVIITGGIDLSVGSVFA
                     LGGVLAAWASQWGFLAALLVPLVVCSAIGLVNGLLIARANMAPFIVTLASLLAARGILL
                     AFTDEGATTYLVPKDSAFAELGQGSVWGFGHPILVALVLFGVGGLLLQRTSFGQTLFAV
                     GGSSDAATLMGLPVARTKILVYTLSGLLAGLAGALNAARLSSGVTIVGVGMELDAISAV
                     VIGGTLLIGGAGSISGTLWGVLLLAVIQNLINQIGSLNSSYQSVVSGGFLIVVVVAQRY
                     LARSRRTT"
     gene            complement(36041..37018)
                     /locus_tag="D6270_RS01775"
     CDS             complement(36041..37018)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606908.1"
                     /locus_tag="D6270_RS01775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_109167091.1"
                     /transl_table=11
                     /translation="MTTPQATLPRPAKPLARLRDPAWYQEYGVYAAVAVVLLFNALFTE
                     HFMTADNLRTQLVQVAPIVIVALGMALVIGTEGIDLSVGSTMALAAALLPLYLGYGLVP
                     ALLIALLAGAVVGAINGTLVSLVGLQPIVATLALFVGGRGLALVMADGQLKQIVNPDIL
                     ALGTGSFLGIPLVVLIAGVLALAVAFLVQRTTFGRQIVAIGGNRAAAGLSGLPVKRVLI
                     GVYVLCGTMAALAGILATARLTASDPSSLGTLMELSAITAVVVGGTPLNGGSIRVLGTV
                     AGALLMQLLRATLVKHDLPDSTAQIAQAAIIIAAVYVARERRSR"
     gene            complement(37015..38652)
                     /locus_tag="D6270_RS01780"
     CDS             complement(37015..38652)
                     /EC_number="7.5.2.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003970920.1"
                     /locus_tag="D6270_RS01780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="WP_109167090.1"
                     /transl_table=11
                     /translation="MAPTEATPRHAETAVAEPVLEARSVSKRFPGVVALDGVSFSLRAG
                     ETHALVGENGAGKSTLIKVLTGVYQSDDGEIRVAGEPVRFARPFEAQQAGISTIYQEVN
                     LVPLMSVARNIFLGREPKNRFGLIDFARMNRETTELLDGFGVRVDPKRPLHTLGIGTQQ
                     MVALARAVSVQAQVVIMDEPTSSLEPREVETLFRVIENLRGQGIAVLYVSHRMDELYRI
                     CDRVTVLRDGRHIHTGDLADLDRMRLVSMMLGRDLAEVRREGLTSFDAAGHDVARTPVL
                     TATGLDRRHQLHDISLQLYGGEVLGLGGLLGSGRSETAKALTGALSLDGGEITVDGKRI
                     GRPTPAAAIRAGISMLPEDRKAEGIIPQLSVRENIVLAAMPRLSRAGIVSREKQDRIVD
                     IFMERLRIKASSPEQKVGELSGGNQQKVLLARWLCLEPKVLLLDEPTRGIDVGAKAEVQ
                     SLIDDLAREGLAVLLISSDIEELIEGADRIVVLRGGAVAGELAGDEVEESRLLEVLADH
                     TPAAEPADRSHEADADGKAPANGQEDPR"
     gene            complement(38739..39824)
                     /locus_tag="D6270_RS01785"
     CDS             complement(38739..39824)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007455262.1"
                     /locus_tag="D6270_RS01785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_109167089.1"
                     /transl_table=11
                     /translation="MMIQRRPRTLAVACLLAATATLAAAGCAKSETSNNAGGDSSQGAQ
                     EAKSPDSTSGSGCSLETYGAPKLDLKNAVVGFSQSEKEANPFRIAETQSIKDEAKKIGV
                     KKLLTTNAQSQLSKQISDIQDMLSQGAQFLIVAPLNSDGLEPALKAAAAKKVPVLTIDR
                     KVNSTACKDYVAFLGSDFVEQGKRAADAMIKVTGGKGKVAILLGASGNNVTTDRTKGFV
                     DQVKAEAPGLEIVAQQTGEFARDKGQQVMEQLIQSKPDITAVYAENDEMGLGALTAIKA
                     AGKKPGKDVKIVSVDGTRNAVQALANGEYNAVIESNPRFGPLAFATAQKFYAGEEIPEN
                     VIITDREYDEANAKDSLGGAY"
     misc_feature    complement(39993..40008)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.33"
                     /tool="antismash"
     misc_feature    complement(40048..40062)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.38"
                     /tool="antismash"
     misc_feature    40088..40102
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.13"
                     /tool="antismash"
ORIGIN
        1 cggcggccag caggtcgccg ctgttgcggg cgatccactg gagggcgaag agccggtgca
       61 gctcggtcag ccgctcgcgg gccgggcctt cgggcagtac ggcggcggcc tgttcgtacg
      121 cctcgcccgc ctgccggtag ccgtacgcct ccaccccgcg cagcgcgggg cccgaggcgg
      181 cgttccaccg gccgagcgga tcgccggccg gggcggcgct gatccgctcc cgggcgcggt
      241 cgaaccagat gtcctccacc gccgccagca gtcgccccag gaagcggggg tcgtccagct
      301 ctccgggccg cccggactcc tcctcgtccc ggacggtgac gctgaacagc atctcggcgg
      361 cggccttggc gtggacggcg aggttgtcgc cctccgcggt gatggcgccc tcgatgccgg
      421 tgaacagttc ggtcatgccg ttgttctcca gcagcccctg ggccccgcac cgctcccggc
      481 actcgacgat gacgccgcgc gcctgccagg tgatccaccc cttggcgacg gcgaccagcc
      541 gctcggcctc ggcccggtcg gcggccgggg cggactccca gcggtccagc gcccggcggt
      601 gcagcaggct catcgcgaag acggtcgcca tcgccccggc gagcgggccg tggtggctgc
      661 ggtgcgcgta gaccggcacc cggcgcgagc cgcgcgagcc ggagaccagc cggtgaccgg
      721 cgtaccggat cgcgagggcg agggtgaccc gggcggagcc gaccgcgcag gcgctcatgg
      781 agagcttgcc gggggtgact cggccgatgg agaggaggaa ccgccttctg cggttggcca
      841 gttcgctggt gaaccgcccg tccgcgccga tccgcccctg ttccccggcg agcagggcct
      901 cgcgcggcac gaagtagcgg tcgaaggagg tgaggcagtg gtcgaccggg gagcccatcc
      961 gggcgggcag ccgccgcacc cgtacgccgg gcagggcgct ggtggcgtcg gtgagcgggg
     1021 cgaggaagag gaagaccccg tggtcggtgc cgtcggcgag gagccgggcg gccaccacac
     1081 cggtcttggg accgcccgcg gggctggtgt tgggcatgaa cttctgggcg ccggagtttg
     1141 gcgtgtgcag gacgaagccg tcgcgttcgc ggtcgtacgt cgcggtcgtc tcgacggccg
     1201 ccgcgtcgtt gccgtgcgcc acctccgtac agaggaaggt gccgatgttc cgcagctcca
     1261 ggaagtccga caggtcccgc agcgtgcccg ggtcgtggtc gaggagggag ccgaggaaga
     1321 ggttgtagtg gatgcccgcg acggtggtca gcgccgggtc gaccgggccg agccattcgt
     1381 gcagagcggc cagggcgcgc gggtcggcgg ccagcctcgc gccgctgtcc agcgcgttgt
     1441 tgaggatgcg gagccggtgg taggagaggg cgagccgttc gtcgggggtg cccccaccgg
     1501 atcggcgaaa cggttctgtt gtgagcagtc gtcgccagaa cccgtgctcc tggcggaagt
     1561 tgtcgccgta gagcactcgg gtgagcagat cgattgtgga gggcctgggt ggttcatgcg
     1621 tggatacggt cacgacaggg taacgatcaa ggaacggcga ggacacccct cgccgttccc
     1681 gaacggccct gcggggtcag gtgcgttgga aggcgagcgc cacgttgtgc ccgccgaagc
     1741 cgaaggagtg gctcaccgcg cgctccaccc gctggtggcg gggctccttc accacgcagt
     1801 cgagggggaa ggcgtcgggg agggagtcca ggttggcgat cggcgggatg agggaacgtt
     1861 ccagcgtcag gacggtggcg accgcctcga tcgcgcccgc cgccgcgagg gtgtggccga
     1921 ggacgccctt gggtgcggtg accggtgggc ggtgcgggaa gagccgggag atgagggtgg
     1981 tctccatggc gtcgttgagg ggggtggagg tgccgtgcgc gttgatgtgg tcgacctcgc
     2041 ccggcgccca ccccgcctgg tcgagagccg cctgcaccgc gcgctgggcg ccccgcccgt
     2101 cgggggccgg ggcggtgggg tggtgggcgt ccgtgctgga accggccccg gtgagcaggg
     2161 cgcgggcccg gccgccccgg gcgcgggccg cctcctcgcg ctccaggacg agcatggcgg
     2221 ccccctcgcc gatcacgaac ccgtcccggt cgtcggcgaa cggccgcgag gcaccggccg
     2281 gatcggcggt acgggtggag agcgcgccca tccgcgcgaa cgcggtcacc accagcgggg
     2341 tgagcaccga ctccgcgccc ccggccacca ccacgtcgca gccgccgccg agcagcagat
     2401 cgcgggcgac ggcgatcgcg gtggccccgg aggcgcaggc ggtcgcgggc gccagggacg
     2461 ggccgcccgc cttcagggcg atggcgacct cgcccgccgc cgcgttgggg atcatcatcg
     2521 ggacgagcag cggcgagacc gcctccggcc ccgacgcggc cagcctggcg gcgttgtcga
     2581 ccaggacgga gacgcccccg acaccgacgc cgagcaccac gccgacccgg ccgccgtccc
     2641 acaccgccgg gtcgagaccg gcgtcggcga cggcctgccg ggccgcgacg acggccagtt
     2701 tcacgaaccg ggccatccgc cacaccgagc ggccgcccac cgcctcgtcc aggtcgatgg
     2761 agtcgaccgc gcaggcgaag tcgaccggga gaccggccag ttccggccgt cggcgggcgg
     2821 tggagtgccc ggagcacagc ccctcccaga agctgtgctc atcagcccct gcgggtgtca
     2881 ccaggccgac ccccgtcacc gcgatggcgg tgccggtggc ggctccggtg ccctgatcag
     2941 cggactgcga catgctgtgt tccttccgta gaatccgtcg agatggtctg cggggtcccc
     3001 ggccaccgaa gtgccgccga accccaggtc aatccgcccc cgaacgcggt gagcagcacc
     3061 cggtccccgc cctggagcag cccccggccc gccgcgtcgg ccagcgccag ggggatggag
     3121 gcggcgccgg tgttgccgac ccgctccaga tgggtgacac agcgctgcgg cgcgatgccg
     3181 acccggtccg cgacggcgcg caggatccgc gcgttggcct ggtgcggcac gaagtggtcg
     3241 acctcggccg ggtcccagcc cacccgctcc aacagcaccc ggcacgagcc ggtcatccgc
     3301 tccacggcgt gctggtagac ggtctggccc tgcatccgga agtacgcgtc cgacagcgcc
     3361 ggcggcttcc cgtccgcccg ggcccgggcg ccgccgccgg ggacggtgat caggccgtcg
     3421 ccggtgccgt cgctgcccag gtcgaaggcg agcagttcac cggggtcacc ggtccgcccg
     3481 gccgccacca gggccgcgcc cgctccgtcg ccgaagacga caccggcgga gcggtcgtcg
     3541 gggtcgagcc aggtcgagta gacgtcggcg ccgaccagca ggatgcgccc gtagagcccg
     3601 gaggcgatca gcccgtggct cagggcgagc ccgtagacga agccgctgca cacggccgcg
     3661 atgtccagcg ccggtacggt gccgaggccg agccgggccg cgagggcggg ggcggtgccg
     3721 gggcagaggt ggtcgggggt ggcggtggcg aggaccaccg cctccaccgg tccggccgcc
     3781 ggggaacccg cgagcagccg tgaggccgcc tcgtaggcga ggtcaccggt ggcgaccccg
     3841 ggcccggcgc ggtgccggcc gccgatgccg gtgcggcggc ggacccaggc gtcgtcgacg
     3901 ccccagtcgg cggggagctg atcgttgggg accggctcgc ccggcaccca gcccgccacg
     3961 ctctccagca ccgccgtgcg cccgccgccg tccgctaagg cgcgctcccg cgcctgcggc
     4021 cccgcaccgc tgcccactgc ccgtctgctc gccacccgct gccccgatcc cgttgtcata
     4081 ctgcgaacgg ttgacgaacg gcgggacgcc tggcgagggt gcgttcgact gggccgaacg
     4141 ggtcatgacg gtttgtcagt tatggccgag cgcctccctg cgccccttca cgaccgagcg
     4201 cctcccggag ctctgccgcg tcgggcgggt tggcaccggc ccgggagacg gtgacggcgg
     4261 ccgcggccac cgcgtggcgc agtacgtcgg tgagggtgtc ccggtccacg gcgtgcagcc
     4321 gctcccgcgc cccggcgccg aggaggccgt gcgccgccag cgcgtggagg gtccccgaca
     4381 tgaacgcgtc gcccgcgccg acggtgtcca cgacctcgac cgtcgcggcc cccaccgtga
     4441 tccggccgcc gggcagcacc gccagggcgc cgtcgccgcc ccgggtgacg aggacggcgg
     4501 ccggcccctg ctccagccag cgcacggcga ctctctccgg ctcctccccc ggatacagcc
     4561 acgccaggtc ctcgtcgctc gccttgacca ggtcgctcag ggcgacgcac gcctcgaccc
     4621 gggccacggc cgccgcgtgg tcgcccatga gggcgggccg cacgttgggg tcgtagctga
     4681 cggtcgcggt ggtccgggcg gcgcgcacga tgtccaggac cgtggccgcc cccggctcca
     4741 ccaccgcacc gatcgacccg gtgtgcacat ggcccggagc ggggccgacg gcgaccgggg
     4801 cgagggtcca ggcgatgtcg aaggcgtacg aggcctgccc ggccccgtcc agggtgacga
     4861 cggccgacgg ggtggcggtc gtggagccgt cggtacggac ggtgactccg gcggaggcca
     4921 ggtggtcccg gatcagctgc ccgttcgggt cggcgccgag ctgggtgagg agggtggcgc
     4981 ggtggccgag gcgggccagg ccgtaggcga cgttggcggg gctgccgccg gggtgggccc
     5041 ggtcgtcctg gtccggctgc cggacgatgt cggcgacgca ttcgccgacg accagcagtt
     5101 cgctgtggtc gagcatgggg gtggatctcc tcaactgccg tgacgtgggt gtcctcgggt
     5161 cctccgcacc cattcagccc gatgctgccc gccgggcgga agccacccgg cgcatcgggc
     5221 accgtccggt caccgttcag gcgccgatac ggccggaacg ggctgcgcgg agggcacgga
     5281 cacctgcggg ctcacggcga cccggcgggc ccagagcagg gccacggcca gcacgaccgc
     5341 ggcggccagc agccagggca gcgggccgag cggcagggcc ccggcggcca gtccggcgcc
     5401 ggcggccacc agctggaggg cgagcgactg gaccgagagg gcggtggcgc ggcccgaggc
     5461 gtcgacccgg cggtgcagca ggtcgttggt gttggggccc acgaccccga gccccaggta
     5521 caccagcccg tagccggtga cggcggccgt cgtggcgagg gggctggtgg cgccggtggt
     5581 gacacccagc aagatcagtc cgagcgcgac caccccaccg ccggacagca ccgcgcgctc
     5641 actgctgcga gtcagcctgg cggcgagcgg ggcgagttgg ctgccgaggg cggagcacag
     5701 gaatccggcg caggcgagtc cggcgaagag cagcgccccg gattcggccg ttcccatcag
     5761 ggcggcggcc cggcccgggg tgagcagttc gacggcggcc agcgcggccc cggcggcgct
     5821 cgcggtcagc aggatgcgcc ggatgagggc gtcccgggcg ccgagccgga gcccggcgcc
     5881 gatggcggcg ggcacaccgc cgacgacccc gcgcagggtg gccgggggcc ggggcggttc
     5941 gggcagggcg ctcagcacgt agaggacgaa gacgatctcg acgagcgcgc cgaggagggc
     6001 gggtacggag agcgggatga cgagcccgcc ggtcgtgccg gtcagccact cccccacgcc
     6061 gatgccgggg ccgagcagcc agggcagccc gccgccgagc agggttccga gcgcgagggc
     6121 cgccgacatg gcggagctgc cgcgcgccag gcccgtacgg aggtcggcgt cggggcccgc
     6181 gtgggcgtgg acggtgtcga cgtaccaggc ttcggcgggt ccgctggaca gggcgcgggc
     6241 gcagcccatc agggccatgc cgagagtgat ggcccaggcc gctccggcga gaccgaagag
     6301 ggtgaaggcg gtgcagttga gcagcccggc ggtggccagg acggcacggc gcccgatgac
     6361 gtcggagagt ccgccggtgg gcagctccat cgcggcggcc gtgagggagt gcacggcgaa
     6421 gaacccggcg atggcggcga ggcccatgct ccggtcggtg aagaggagca cgccggtcgc
     6481 gacggacatg ccgacgggga gccagaagag gaaggagacc gtggtgaacc ggcggcgcgc
     6541 ggtcagcggg tcgaggccgc gcccggtggg agcgggcggt ctcggtatcg acgcctcgtc
     6601 gccggaccgg ggggtgtcgg ttccggcgct cacgaggcgg gcccctccgc gtcgggggcg
     6661 ggttccggtg ccagcggaag tccggccgtg acgaccacga cctgttcggc acgggggtcg
     6721 tccgcgtcgc gggcggtcag ttcggccatc ttcgtggcga ccgtctccca cagctcggtc
     6781 agcgactccg gggtcagccg gggcagggag tcgctcaggc ccgacggctc ctgccaggcg
     6841 gtgtccagcc ggccgttctc caggtcgtcc tcgtggcggg ccagcgagcg ctccaggtgt
     6901 tcgagctggc ggcggcggag cgtgctgagc gcggcccggc ctccgggggc ccggtgcatg
     6961 gcctcgttgc tccacgaggt gagggtgtgc acggccttcc agcggcgttc gcggctgtcg
     7021 cgatggtcgg cctcggcgac gaacgcgtac ttggcgagta cccgcaggtg gtagctggtg
     7081 gaggcggacg actcgcccgt ccgcgcggcc agctcgctgg cggtggccgg gccgtgccgg
     7141 cgcagcagcc cgagcagttc gatccgcagg gggtgggtga gggccttgag cgcggctccg
     7201 tcgcggccgg gatcgagtac gcggcgggtg ggttcgctgt ccatggcagg agcgtaggac
     7261 ggatcgccca ctttcccaaa gtatttttgc agaatatttt ttggagagtt ggaccagacc
     7321 ctctcccctc agccggcgga ccgcgctcga aggacctcga tgacctccct gcaccagtcg
     7381 cggttggcgc gctcgaagtc cagcccgcgg cggcaggtca gataggggcc gatccgctct
     7441 ccgtaccgca ggaactcctc ctccgcccgc tcgccgcgca tccccttgag cagcgcctcg
     7501 aactgcgcgg ccttggcccc ggcgaactcc gcccgctcgg ccagccgggc gatcagctca
     7561 ccggggtcga gatggtcggc cgcctggacc ttgacgagca ggtcgtcccg gatgaacgag
     7621 ggcttggcgg cgaccgccgc gaaccgctcc agctcggcga gaccgccgtc ggtgacccgg
     7681 aacaggcgct tgttgggccg ggtgtcctgc acgacctcac gcccggcgac caggccctcc
     7741 ttctccagct tggccagctc ggcgtacagc tgctggggca gcgcgtgcca gaagttggcg
     7801 acgcccatgt cgaaggcctt ggccagctcg tatccgctca gctcctcgtc cagcagcgcc
     7861 gccagcacgg cgtggcgcag ggccatcgga ccgcctccct ctcggtgtcc gcgcacccct
     7921 gtccaggagc gcgcggtcca tgatagtcat gaaagtgact actcatattt atgagtagtc
     7981 actttcatga gcaccagcct tcgaggagac gccatgacca ccgcagtgga ccgcttccgc
     8041 acggccgtcg acacccgcga cctcagcgcc ctggacgatc tgttcaccga ggacgtccgg
     8101 ttctacagcc cggtgaagtt caccccgttc gagggccggc ccatggtgct ggggctcttc
     8161 ggggtcctgc tgcgcacctt cgaggacttc cgctacgtcg gagagttcgg gggcacggca
     8221 cagaccagcg tggacggcgc cgaggccccg gccgcggtcc tcctcttccg agcgaccgtg
     8281 aacggcaagg agatccacgg catcgacctg gtccacctcg ccgaggacgg gcggatcaag
     8341 gaattcaccg tgatggtccg gccccagtcc gccgtgcacg cgctcggcga ggcggtcctc
     8401 gccgggctgg tggccgacgg actggtcccg acggagtagc cctctcccgg ctatccctcc
     8461 agcgcgtccg cgaccaggcc gaggaagcgg gcgtggtcgc gggggccgta caggggctcc
     8521 gggttccacg gcacgaccgg ctccccgccg tcccggccca gctcgtcggg ggggcggcgt
     8581 gggcgcggat gtcggcgagg atcacatcgg ggcgcagcgc gaaggtcccg gcccggtcga
     8641 gggtggacca gttggccccg gggcccgggg ccggctccac caggtggacg ccgagctcgg
     8701 tcaggacgcg cagctcgggc cacatcccgg ggcgggcgac atgggcctga tcgggtccgg
     8761 ccggggagag ggcgaggacg cggggcgggt cggccgcacc ggcggcggcg acggcccgca
     8821 gccgctcccg ggcggcgtcg aggtcggcgt ccgcgtcggc gcggcccccg gcgccgagcg
     8881 agcgggccag ctcggcgaac cggtcgccga tctcctcgaa cgtccgggcc tggctcacat
     8941 cgaggacgac gaccgggacc cgctcctcca gctgcttggc ggtctccggc gccagcccgt
     9001 acacatggcc gttgccgtag ctcaccgcga ccaccagatc ggtcccgccg ctcagcagcc
     9061 gctccacgtc cagcccgctc cccgcgccga cgtacgcgac ctcgtccagc ggaagcgtgc
     9121 cggtcttctc acggtcgggc tcgggaccgt cgtggtcgga gccgaagatc ccctgcggcc
     9181 ggatgccgag gccccacagc gtcgccccgg cctggacata ggcgagcacc cgctcgggcc
     9241 gccggggcgc cgtcgacagc tgaccccggt cgtcggagaa acgccattcg ctctgttccg
     9301 tcacgccaca cacgcccctc tgccaccgac tgccgtaccg cttgtgcgag ttcgtacagg
     9361 tgtacctgcc cacctgctca ccgccacacc cctcgacccg gcaccgacct tcgtaccacc
     9421 ccgtatgcgg cgcgacgggc ggtcgagttc acccggtgtt agaaaggaga cacgttcagc
     9481 gatcttggcg gccgcctccg cccgccctct ccgatggaga caactcccca tgcgcgcacc
     9541 cctcttgaaa gtgactctgg ccgccggcct cgccgcgtcc ctctgcgccg ccccgttcct
     9601 caccgatacg tcggcgagcg ccccggccgc tccggctccg gcttccggag cggtgcgctg
     9661 cccggtcgtg gacgtgctgg tggtccacac ccccaaggcc gccgaacggc tcggcggcca
     9721 gcaccgggtc ccggcgtcgg cccagcggat cgcgacccgg atgaaccgct cgctggcggc
     9781 cgacgggctc tgcgggacca tccggatcgt ccacccctac acggcgaagg agtacgacgg
     9841 ttcggaggag ttccgcgccg cgtacgccgt actgaaggac cacacctcgg ggctcgggcg
     9901 ccaggtgcac gagcaacgcg agcggtacgg cgccgatctg gtgacgctcg tcgtggagcg
     9961 ggccgagcgg ggcggcggca ccgcggacta cacgtccgcc ctcgacagct ccacccatga
    10021 gtacgcgtac tccgtcgtcg aggtcgacgg gatcgaactg gactcggcga gccacgagat
    10081 cgggcacaac ctgggcctgg cccacgaccg cacgacgctg gcgtcggaca ccggcgggtc
    10141 gatgaacgtg agccgcaccc gcccgtacaa caccggctgg atcaccgagg acgggcagca
    10201 ctacaccctc atggcgtacc gcgcctcgtg cggcacccac tgcaagcgca tcagccggtt
    10261 ctccagtgcg aaggggagct ggcggggcca ccggctcggc gacgaatcga acgacagtgt
    10321 gcgggtgctg cgcgagacga tgccgatcgt ggccggatac cgttcgaaga cctgacccgg
    10381 ccgggccccg tggcccgtga ccgggccgta ccgtcacgcc gccacgacaa ggaccccctc
    10441 atggaccgca tgcgcgccgt gcgcctgcac ctgcccaccc gcacgctctc cgtcgaggag
    10501 gtggcgaagc cggtgccggg gcccggcgag gtgctggtga aggtggcggc tgccggggtc
    10561 tgtctctccg atgtgcatct cgtggacggc acgctgacgc cggtgtatcc ggcgggcgac
    10621 tccgtcaccc tgggccatga ggtggccggg accgtcgacg cgctcgggcc cggtgtcgag
    10681 ggctggacgg ccgggcagag agtggtcctc caggcgggcg agcgacgcgg aggccggacg
    10741 cacacgagag gggtcgacta cgacggcggc tgggccgagt acgccctcgc ctcggccgcc
    10801 accctcgtcg ccctgccccc cacgctcccc ctcgaccagg cggcgatcat cccggacgcg
    10861 gtctcgaccc cctgggcggc ggtgaccgtc accggtgagg tacgccccgc gcaggccgtc
    10921 gcggtctggg gcgcgggcgg gctcggggca cacgccgtgc aactgctgcg ggccgtgggc
    10981 gcgtgcccgg tcatcgcggt ggacccggcc cccgccgccc gggaccgggc cctgcacttc
    11041 ggggccgatc tggcgctgga ctccggagac ccgctgctgc gggagcaggt gctcggagcg
    11101 acgggcggcg cggggctgga ggcggccttc gacttcgcgg gcgtacccgc cgtccgggag
    11161 caggccttgg gcgtgctggc accgaagggg cgcctggtgc tggtggggct gaacgaccag
    11221 ccgctgacgg tcgcccactc cacccggttc agctacctcc agcaccggat cctggggcac
    11281 tacggctccg aggagcacca tgtggcacag ctcgtccggc tcgccgaggg cgggcggctg
    11341 gacttctccc ggtcgatcac cggcgtactg ccgctggagg aggcggcgac ggcggtgcgg
    11401 cggatggaga ccaaggaggg cgacccggtc cgcctcatcc tgcggccgta gcgggatcct
    11461 ccttcggttc cggcttcggt tccggttccg gttccggctt aggctccggc ttcggcttcg
    11521 gcaccttcgc cggctcccgc cggtccagct ccacgttgaa ctgggcgccg gcgagcaggg
    11581 agaggttggc gaaccagacc cagatcagga agaccaccag cccggcgagg gagccgtaga
    11641 gcctgctgta gctgccgacc tgggtcgcgt acaacgcgaa gagcgccgac gcggtgagcc
    11701 agaggaaggc cgccagcacg ccgccgggca ggccgcggcg gacgccgcgc gcggagcggg
    11761 ggccggtgct gaagaggacc aggatcaggc aggcgacgag gcagagcagc accggccact
    11821 tcaggacgac ccacagggtc tgcccctcgt ggggcaggcc gacgcggccg ccgagccagc
    11881 gggccagggg gccggtcatg acgagggcga aggcgctggt catcaggagg acgagcaggc
    11941 cgatcgccga gaggacgatg atgtgcgcct ggcgcagtgg cgggcggttg tcccggacgc
    12001 cgtgcatggc gtgcatcgcg cggcggaaga ccgcgaggta gctgcacgcg gaccacacgg
    12061 cgctgaccga cccggtggcg acgagcagcc agacggcgga gcgcttctcg gtggccgcct
    12121 ccagcgggcg gcgcagcgcc tcccccgact cggcgggtgc gaaggccgtg atgtcggcga
    12181 tcagggcggt ggtcgcgccg gggttggcga ggccgatcac ggagacggtg acgaggaggg
    12241 ccgggagcag cgcgaggatg gcgtagtagg tgagcgcggc ggcccagtcg gtgatgtcgt
    12301 cgttccacag cgatacgggg gtgcggcgca gggcggtcag ccagtggcgc ggcgcgcggg
    12361 ggcgcccggt ggcggtgcgt tccgcggctg cggcggtctg ggtgggcaag ctggttctcc
    12421 ggggacgtgt tcggacgcgg cggggcgggg cggggcgctc gtccgacgga cgccccgact
    12481 tccctcgatc ctctcctgcc acgtaccggc ccgggcacac ctgcccgggc cgtatggcct
    12541 tccctgatgt tccgtgggcc gtcccggcgg gcggtcagtc gttgacggcc gtgaggagga
    12601 ccaccgcgtc ctggagggca aggagcccgt gccgctcctg cgggatcggg tggagggtgc
    12661 cggccgggag gtcggcgtcg ccggagccgg cggtgaggcg gaccgtgccg cgcaggacca
    12721 ggagggaggc ggcgggcggg gcgttgtgtt cgtcgagggc cgagccggag gtgagcgcga
    12781 tcaccgtctg gcgcaggggc ggttcctgga tgaggaggtg cgcactgcgg ccgtgcgcgg
    12841 aggtgcgggc ggcggccagg tgctcctcgg cgagtgcgtt gaggtcgtcc atggtgccta
    12901 ctctgccgca gcgcctgccg ccccgcgatc gtgccggccg cgggacggcg gggcggatcg
    12961 cgacgcctgg agcgggccag ctggatgaac gcaggatttc cctcatgtta cgcaagtagc
    13021 cgacagctgc acgcacaagg cggcgaccca gatgtggggc tgctcagcgg ggcgctttcg
    13081 cggtcgaacc gcgcaccacc agctccggct cgaacagcag ctcgccgggc ggcaccgcac
    13141 ctccctggat gcccgcgcag agcagttcga cggcggcccg gcccatcgcc tcgatgggct
    13201 ggcggatcgt ggtcagcggg ggttcggtgc agctcatgaa ggccgagtcg tcgaagccga
    13261 cgaccgagac gtccgagggc acgccgaggc cacgcctgcg ggccgcccgg acagcgccga
    13321 gcgccagcgg gtcgctggcg cagatgatgc cggtgatccc tcgctccagc agccgggagg
    13381 cggcggcctg accaccctcc agggagaaca tcgacctctc gatgttctcc tcgggcagct
    13441 gccctccggt ggcggatgcg acggagcggg ccgccgccag cttgcggcgg gagggcacgt
    13501 ggtcggaggg accgatcacc acgccgatgc gctcgtggcc gagggaggcc aggtggcgcc
    13561 aggcgcgttc gatggcgacc gcgtcgtcgc aggagacgca ggggaagtcg agtccttcta
    13621 tgggggcgtt gatcagcacg acggggatgc gccgctcggc cagccggtgg tagtgctcat
    13681 gggcctcgtc ggcctgggcg aagaggccgc cggcgaagac caccccggag acctgctgct
    13741 ggagcaggag gtccacgtag tcggcctccg agacgccgcc cttggtctgg gtgcacagga
    13801 ccggcgtgag cccctgctgg gcgagtgcgc cgccgatcac ctcggcgaag gccgggaaga
    13861 tcgggttctg gagctcgggg aggacgaggc cgaccagccg ggcccgctcg ccgcgcagct
    13921 gggtggggcg ctcgtagccg aggacgtcca gcgccgtgag cacggactgc cgggtggtcc
    13981 gggagacccc gggcttgccg ttgagcaccc ggctcaccgt ggcctcgctg accccaacct
    14041 tcttggcaac ctgagcaagt cgtcgcgtca tgaccgcaag actaacgtaa gcaatgcaaa
    14101 cttccgactt accgatgcaa ggaatatacg cggaaagggc gcctcccggc caacgggaga
    14161 caccccttcc tccgttctgc ccgcctcctc gctacgggtt gatgttgatc ttgaaggtgg
    14221 aggtcgtgtt ccggatgtcc tgggcgttgt tgctgagcct cagccggttg aaggtgacct
    14281 cgccgaccgc gggaccctgc cccgcctccg gcatctcgtt ggcccagagg ccgaagccgg
    14341 acttggcgtc gaaggcgtca ccgctcttgc gcgcacccga gatcgacaca tcggtgagca
    14401 cggtgtcctt gatcgggaac tgcggctgtc cgccgacgta gttcgtctgg aacatgatgc
    14461 cgctgtacgt cggatcgacg atgtccacgt tggagatccg gatcccctgg aacaccttgg
    14521 aggcggagaa gagccagatt ccggggaagg tctgcgaccc ccagaagtgg ccgccggacc
    14581 ggacgatcga gacgttctcg atcttcgtcg gctgggtccc gaagccgttc atcggatagc
    14641 cgaagtccag cgagctgacc gtgatcccgg agtacaccag ggtgtcggcg atgtggatgt
    14701 tgcggaaggt gttgtcgtac ccgccgtaga cggccacacc cgccgcccgc caggtgagga
    14761 tcgaggtcag gttctcgtag aggttgttct tcatgtccgc tcccccggcg tcgatcgccg
    14821 agaagagcgc gaagctgtcg tcaccggtgg ctcgcgcctc gatgttggtg acgaggttgt
    14881 cggtggaccc gttggtcatg ttgatgccgt cggcgaacat gttgcggatc cgggagttct
    14941 tgatggtgat gctgtcggtg ttggcgcccc agtagaggca caccatgtgc tcgttccaga
    15001 tgttgtcgat cacgatgtcc gacacgttgg cgaagtcgaa caccttgccc ggcccgtcga
    15061 tgcgggaggt gtagttgccg aagtaggcga agttggcgaa cgaggacccc ttggcactgg
    15121 cctcggcccg gaagccgatg tcggtgttgt cctgtgtgct gggggcgttg aaccgggtgt
    15181 accagggccc ggcgccgacc accttgaccg ctttcccgta cacctggaac ttgctggcgg
    15241 tgctgtactc cccgggcggc aggtagacgc cgaccaggtt tccggtggtg tccatgcgga
    15301 cccggtccag ggcgttctgc acgtcctggt gggtgaaccc ggtcggcatg gtgtacgcgg
    15361 cggggttcgg gttggcgacc ggtgcgacct gctccaggct gatgaagtcg atcgcgtacg
    15421 tcgtggagtt ggcggcgtcc ttctggagcc ggatcttggc cccggccggg acggtcttcc
    15481 ccagcatgac gttggcctcg tcatagatgt ggcggggagc tccggagccc ggggagttgc
    15541 cgggtgcggc ctcgttcccg tacagccagg cgtacttgga ggtgaggtcg atggctttga
    15601 ggaaggtgcc gtccacgtag aggttcagcg tggagttgat cccgccgccg cccgcggagt
    15661 ccgggatgga gaaccgggtg acgagcgtgt tggtggccgc ccgggtggtg aactcgacgt
    15721 agttgccgct gttgttgagg gtgacggcct tacgtccgga ggcctcgccc gcgatgtcgc
    15781 cgacggtccg gttggggccg acgacctggg cgccgccgcc ggtggtgccg tcctccgcct
    15841 cgtacatggc gtacggcatg ttggcgccgc ggccgacgaa gagggactcg gtggaggtgt
    15901 tgttctcgcg cttgaccggc agttcgttgg cgtcggccgc cagcaccgtg cgcagggtgt
    15961 acgagccgtt gacggcggtc caggtgccga gggagacggg tgcggtggtg gcgcccgccg
    16021 cgatggtccc ggtgtgcgcg ccggtgaagg tcttcaccgt ggcgccctgg gagttgagca
    16081 gcgtgagcgt gatgccgtgg ctgccgctcg cggaggcgat ggtgccctgg ttcttgatgg
    16141 cgacggagaa ggtgacggtg ttgcccgccg acggggcgga gggcgaggtg gtgacggatg
    16201 tcgcgaccag gtcggagctg gagaccggct gcacgaccag cggggaggcc gccgtgtagg
    16261 tgttgttggt ctcgttctgc tcgatgacct cgttctccgg gtccgcgacc gcgctcagga
    16321 cgtaactgcc cgcgccccgg gctccgatgg ccgcgctgac ctgggtggag gcaccggcgg
    16381 ccagggcgcc gacgctgccg gtggcgacct tggagccgcc gagcctgaac tcgaccttgc
    16441 tggccggtgc ggcgagcgca cccgcgttgc ggacggtggc ggtcagggtg atggtgtcgg
    16501 actccaccgg ggtggccggg gatgcggtga tgccggtgac ctggaggtcg gggttggccg
    16561 ccggggcgcc cagcacctgg aactccgcga cctggccggc gccggagccg ctgttggcgg
    16621 tgaacttcag ctggacgtcg gcgatacggg cggagaccgg gatggtcacc gtgttgccgc
    16681 tcgccgggct gaaggcgtaa tccttcgcgg ctaccaggga gttgaaggac gaggagctct
    16741 gctcgcggcc caggacctcg atccgctggg tgcgcgggcc ccagctgctg tccgggttga
    16801 gcttgacgac gacgctctgg gtgtcggcgt tggagccgag ctggaccgtg agcgtgttgg
    16861 ggtaactgcc tcccgcgccc tcccagtagg tggcggtgct gttgtcgttg gcgttggcgg
    16921 cgacgaaggt gtgcaccacc gaggaggccg tgatcggctt gttgaccgcg aggttggagg
    16981 cggcccccgt ggagccgttg cgcgtcacgg tgttgctgtc ggtcgacacg ttgcccgccg
    17041 cgtccttggc ccggacgaag tagctgaccg tggcggtggc cggctgggtg tcggtgtacg
    17101 tcaggacgtt gcccgcgacc gagccgcgca gcacgttgtt ggcgtagacg tcgtagccgg
    17161 tgacgccctt gttgtcggtg gatgcctgcc aggtgagccg gatctggccg gcggccggct
    17221 cggtgaacgc aagcgcggtg ggggcggtgg gcgcctgggt gtcacccgtg tcaccggtgc
    17281 gggtgacggt gttgctgttg gacgagacgt tcccggccgc gtccttggcg cgcacgtagt
    17341 acgagacggt ctgcccggcc gggcgggtgt cggtgtacgt ggtgacgttg cccgcgacgg
    17401 tggccagcag ggtgttgttc gcgtagatgt cgtagccggt gacgccggtg ttgtccgtgg
    17461 ccgccttcca ggtcagccgg atctggccgg tggcgggctc ggtgaacgcc agatcggccg
    17521 gtgcggtcgg ggcctgggtg tcgccggtcg cgggtccgta gacctccagc tcggccagct
    17581 gggccgaggg gctgccggag ttggcggtga ccaggacgcg gacgtaccgg gtggtggtgg
    17641 gatcgaagga gatcgtcgcc gactgtccgc ccgccgcgtc gaagcggtac tccttcgagg
    17701 cggtgagatc ggtgaactcg gccccgttgg tggaggcttg gagcttcagc gtctggctgc
    17761 gcgccgccca gccgtcgggg agccgcagga cgacccggtc cacgcggacc gacgagccga
    17821 ggtcggcctc gatccactgc gggaacgcgt tctcccggct cgcccagtag ctggcccggt
    17881 tgccgtcgtt ggcgttggcg gcgacgtagc tcccgttgcc gctgctggcc ttgagggtct
    17941 tcccggccgc gaggttgccc gacgactcgg cggccgcccg gacctccagc tcggagagct
    18001 gagcggcctg ccagccggtg ttggcggtga tgttcacccg gacgaagcgg gtcagcgtgg
    18061 ccgggaattc caccttgacc gtgttggcgg agccggggct gaaggagtac gccgccgaac
    18121 ccttcagggt cgcgaagctg gtgccgtccg cgctgccctg gagggagagg gtctgggtgc
    18181 ggctctccca ggacggcggg agcttcagcg tcacctcgtc gacgcgggcg gacgagccga
    18241 ggtcggtctg cacccactgg ggcaggttgc cgcccgcgct ctcccagtac gtcgacgcgt
    18301 tgccgtcggt gatgttgggt gcggggtact cggcatgggc gctgctcgcc gtcgcggccc
    18361 ggcccgcggc gaggttgggt ccgtcggccg ccgaagcggt gagcgacggc cagccgatca
    18421 tcagaagact ggtcgtgacc aaggcggata tcgcccgcca tctccagcgt tgggctctca
    18481 tagctccccg atcttcggcc tcggcgcggg acgcgtcgaa ggcgcggctc tggatccgta
    18541 gtcaggaaac acgcgattct gcacgcacta cggcttggtt ttgcgttgtg cggtcagaga
    18601 gttgcagaga aatgagagac cgtccactgt tccggcaaca gccggatggt gcgggccggt
    18661 gagcggatca gctaccgcga tcaccgctca ccggccccac ctggcggtgt gtcagagacc
    18721 gccggtgtag aggagcagat cgggcgagcc ctggccgagg ccggagagca ccttcggggt
    18781 ggccgtgtcg gtcagccacc gcgtgacggc ggcgggtgtg gccgaggggt tctcctcctt
    18841 gtagagggcg gcgaccccgg cgacgtgcgg gctggccatc gaggtgccgt tcagggagac
    18901 ggtgccgccg ccgagcttcg cggagacgat gtcggcgccg ggggcgtaga gcgagaggca
    18961 ggagccccag ttgctgaacg aggtctcccg gtcctggcgg tcgctcgcgc ccaccgtgac
    19021 gacgccgtcg gccgcggccg gggagacgtc acaggcgtcc tggtcctcgt tgcccgccgc
    19081 caccaccggc aggacacccg cgtcggcgac ggcttcgacc gccgcgtcga cggcccggga
    19141 gcgggccccg ccgagcgagg cattcaggac ggcgggggtg gagccggccg ccgcgtcctt
    19201 ggccacccag tcgaacccgg cgatgatgcc ggcccaggtg ccccggccct ggcagttcag
    19261 gacccgtacg ccgaccaggg aggcgtcctt cgccactccg gaggtggagc ccgcgacggt
    19321 cccggcgaca tgggtgccgt ggccgttgca gtcctgcccg tcgcggccgt cgccgaccgc
    19381 gtcgtacccc ttgacgaccc ggctgccgaa ctcggcgtgc gcggcgtcga tcccggtgtc
    19441 gacgacgtac accttcacgc cctcgcccgt ggcggtggtg gtgaaggtgt cgtccagcgg
    19501 cagggcgcgc tggtcgatcc ggtcggtgcc ccaggtggcc gcgggggccc ggaagaggcc
    19561 gcccgtccgg ggcgcctcca cggccacttc ggcgttctcc tcgacggcga gcaccccggg
    19621 gacggcccgg acggcctcca gttcggtagc ggtgagcgtg acggcgaacc cgtgcaggac
    19681 attcccgtac gtgaacaacg ggcggagccc gaactcctcc agcacggtgt ccggagagag
    19741 ttcgggctcc agggtgacga tgtactgccc ggggacggcc cgggcggaac gctccaccgg
    19801 gaccccttcc ggtccggtgt cggcggtggc cggggtggtg gtgccgatca gcggtgcgat
    19861 cagcagcagg gcggccgggg cccatcgggc acgcaggcgc atgcaggtct cctcgggtgg
    19921 gggcgttcgc ggagcggata cgcatccgcg aagagcgaat acccgttccg cggcccccgc
    19981 ccgtgcggcg cctgggccgt tcagccggac agcgcaacgc ccgccgcgcg ctccagctcg
    20041 gccagttccc ggtcggggtc ggtcccgggg tcgtggttcg cccagctgcc gaccgccact
    20101 tcggcggtga tgccgggccc gaatccggcg atcaggccct gcgcggactc ggccgcgcca
    20161 ccgtcgtcga agaggcgggc gagcgcgtcg aagacgacgg agctggcgat gttgccgcgt
    20221 tcggtgaggg tggcccggct gtagcggaac atctccatcg gcaggttcag gaagtggcag
    20281 aggtcgtcga ggatgcgcgg gccgccggcg tggacgatga agaagtccat gtcgggcacc
    20341 gaccagccgt gcaggtcgac caggtcctgg aggaccggcg cgagcatctc catggtgccg
    20401 ggcacgcgct tgtccagcag gaagtggaat ccggtgtcgc ggacggcgta ggagatccag
    20461 tcctcggtgt cgggcacgag gtgggagccg ttgcgctcca gcttcatgcc ggtgccgccc
    20521 tgcccccgga cgacggcggc ggagatggcg tccccgaaca ggccgttgga gagcagcgat
    20581 ccgacgccga tgtcggtggg ctggtagcag agcgagcaga actcgcagga gacgatgagg
    20641 acgttggagt cggggtaggc ccggcagaag tcgtgggccc ggttgatcgc cgcgcccccg
    20701 gccgcgcagc cgagctgggc gatgggcagt tgtctggtcc cgggtctgaa ccccatggtg
    20761 ttgatgagcc aggcggtcag cgagggcatc atgaagccgg tgcaggagac gtagacgatc
    20821 aggtcgatgt cgtccgggtc ggtcccggcg ttggcgaggg cctgccgtac gacttcgggg
    20881 acccgggttt tggcctcggc ctcgtacacc tggttgcgca gctcgaagcc ggggtgcctg
    20941 agggtctcct cgatcggctg caccaggtgg cgggtctgga ccccggtgtt ccggatgagc
    21001 ctcaggacga ggtcgcgctg ggggtgcccg tggtgggtct cccgggccag ctccagggtc
    21061 tgctgcatcg tgatgacgtg ttcgggcaca gcgatggcgg gtcggcacag ggtcgccatg
    21121 ggttctcctc gtatctggga gcggaggctc tcgtcaccac gtgacgggca gggcgagcgg
    21181 gtaacgccag atggacgtcg tgttccaccg gatgtcctcg ggctcggcgt cgagacgcag
    21241 ggccgggaag cgggccagca gggtggagaa ggccacttcc agttccatgg tggcgagcgg
    21301 cgcacccagg cagtggtggg cgccccagcc gaacgtcatg tgcgggatcg agggcctggc
    21361 ggggtccagc tcgtcggggc ggtcgaactt ggcggcgtcc cggttggccg tcaggtacga
    21421 cacatggacc acgtcgcccg ccttgatggc gaccccgccc agttccacgt cctccagggc
    21481 gatccggggg atgccgacgc ccttgcggaa ggggatatac cgcagcagct cctccagcgt
    21541 gcggggcagc cgctcgggtt cggcctggag cgtcttcagc agctggggcc gggtgagcag
    21601 ggtgtaggcg atgttgccga gctggtaggt cgtggtgtcc tggccggtga tcagcaggac
    21661 catcgccatg acggccagtt ccctgtcgtc gaggagttcg tcgccgtcgc gggcggtggc
    21721 cagggtgctg atgaggtcct ggcccgggga gcggcggcgc tcggcggtca gctcggtgaa
    21781 gtagccgcgc agttcggcct tggcccgtac ggcgtcctcc ttgcccgccg cgccgacgtt
    21841 catcatcgtc atggcgtggg cgcgcagcca cgggcggtcg gcctcgggga tgtcgagggc
    21901 ctcgcagatg gtgatcagcg gcagcggaga ggagacccgg gcgacgaagt cggctggtga
    21961 gccctcgtcc tccatcccgt ccagcagccg gtccacgacg cgctgggtgc cctcccgcat
    22021 ctgctcgacg cggcgcgggg tgaagctctt ggcgaccagg ctgcgcagcc ggctgctggc
    22081 gggcgggtcc atgagattga tggactcggc ctggacgatc ggctcggggg tcatccgggg
    22141 gaagtcccgg ccgagtacgg cgctgcggct gaagcgccgg tcggtggtga ccgtccggac
    22201 gtcctcgtac cgggtgacga gccaggcctc gccctctccg tacgccatac ggatgcggga
    22261 gacgggctcc tcggtgagca gttccttgag ctgggggtcg aactccagct gctgtgcgaa
    22321 gtcgaacgga cagctccgta cggtttcctt gtcgtggacc gaggggtcgt gcgtcgaggc
    22381 gtcgtgcacc gaggcgttct gcaccgaggt ttctcccaac gaccggttcg ggggtttcag
    22441 ggcgtcccgg ctcagggccc ggaacagacc tcccctgtgt cccccgtggt accgcgaaac
    22501 atgtcaccgg tgttccgcag tcagccgatc agagggggcg cacgctcccc cctgtcaccc
    22561 cgccaggacg tggtggcggc cgatcggcag catcaggggc cggccggaca cggggtcctc
    22621 gatgacgcgg ctgtccaggc cgaagacggc acggacggtc tcctcggtca gcacctcggc
    22681 cggggcgccg acggcgtgca gggtgccgtc ggcgagggcg atgaggtggt cggcgtaccg
    22741 ggcggcgagg ttgaggtcgt ggagcaccat cacgatcgtg gtgccgcgcg accggttcag
    22801 gtcggtgagc aggtccagga cctcgatctg gtggctggcg tccaggaacg tggtgggctc
    22861 gtccagcagg agcaggtcgg tctgctgggc cagggccatg gcgatccaga cgcgctggcg
    22921 ctggccgccg gagagctcgt ccacggcgcg gtcggcgagc ggttcggtgg ccgtcgcctc
    22981 cagggccgag gccacggcgg cgtcgtcctt ctcgttccag cgggagaaca tcgactggtg
    23041 ggggtggcgg ccccggccca cgaggtcgga gacggtgatg ccctcgggcg ccaccggtga
    23101 ctgcggcagc aggccgagcg tacgggccaa ctccttggcg gggaggcggt gcacctcctt
    23161 gccgtccagc acgacccggc cctcgcgggg tgcgagcagg cgggacatcg agcgcagcag
    23221 ggtcgacttg ccgcaggcgt tggcaccgac gacgacggtg atcctgcccg gcggtacgac
    23281 gaggtcgagg gaggagacga ccgtacggtc gccgtagccg agggtgaggt gttcggcggt
    23341 cagttggtgg tcggtggtca tagcgagcct cccgcccggt tggtgcggat gatgaggtag
    23401 acgaggtagg gggcgccgag gacgccggtg acgacaccca ccgggtagcg ctcgccgaag
    23461 gcgaactggc cggtgaagtc ggcgacgagg accagcaggg agccgacgag cccggcgggc
    23521 accagcaggg agccgcccgc gccgacgatc cgggccgcga tggggccgga gaggaacgcc
    23581 acgaacgcga tgggcccggc ggcggccgtg gcgaaggcga tgagcccgac ggcggccacg
    23641 atcacggtga tccgggtgcg ttcgacccgt acgccgaggg cggaggcggt gtcgtcgccg
    23701 agctgcatcg cggagaggct gcgggcctgg ccgaggagga gcggggtgag gacggcggcc
    23761 gcggccagga cggggacgac ctggtcccag gtggcgccgt tgaggctgcc ggtcagccac
    23821 cgcatcgcct cctggaggtc ccattcggcg gcctgggaga ggacgtagga ggtgacgctg
    23881 tccagcatcg cggagatgcc gatgccgatg aggatgagcc gggtcccgac gactccgccc
    23941 cggaaggcga gcgagtagac gagcagggcg acaccgaggc ccgcggcgat ggcgagggcg
    24001 gagacctgca cctcgccgag ggagagggtg acgatggcga tggccgcggc cgcgctcgcc
    24061 ccggagctga tgccgatgat gtcggggctg gcgagcgggt tgcggagcat cgtctggaag
    24121 gtgacaccgg ccagcccgaa gctgaatccg gccaccaggg cgaggaccgc gcgcggcagc
    24181 cggagccgcc cgacggtgaa ggtggcgccc ggcacctgct cgccgaggat cacccggaac
    24241 acgtcgccgg gcgggtagaa cgtccggccg gccatcagcg tcacggcgaa cgcggtgacg
    24301 acgagggcgg ccaggaccag gatcaccagg cgcctgcggg aggcgccccg gatacggcgg
    24361 cgggtggcgg ccgcgacgga ggccgggtac gcctccttgg gggccggccg ggtgagggcg
    24421 ggggcgctca cagggcacgc accttctgtc ggcggacgat gtagatgaag aagggggcgc
    24481 cgatcagcgc ggtcacgatg cccacgtcga tctcggcggg gcgcgcgacg atccgcccgg
    24541 ccacatcggc ggcggtgagc aggaccgcgc cgagcagtgc cgagagcggc agcagccagc
    24601 ggtggtcgac gccgacgagc agccggcagg tgtgcgggac gacgagcccg acgaagccga
    24661 tgggtccggc gacggcggtc gccgctccgc acagcagtac ggcaccgagc gcggcgaccg
    24721 cccttgcgac ggcgacccgt tcaccgagtc cggccgccaa ctcgtctccc agagcaaggg
    24781 agttgagggc gcgcgcggag agcaggcaga tggcgaagcc gaccgcgagg aacggcgcca
    24841 cctgtccgat gcgctcgaag gaggcgccgc cgacgccgcc gatctgccag agcttgaagc
    24901 ttccggcgat gtcgttacgg ggcaggatga cggcgctgac gagcgaggcg aacgcggcgg
    24961 aggtcgcggc cccggcgagt gccagcttga gcggggtggc cccgcctctg ccgagcgtcc
    25021 cgacggtgta gacgaacagg gcggagaggg cggcgcccgc gatggccacc cagatgtagc
    25081 cggtcggcga ggagagcccg aagaacgcga cggcggtgac gacggcgagc gaggcgccca
    25141 tgttgacgcc gaggatgccc gggtcggcca gcgggttacg ggtcacgccc tgcatcaccc
    25201 cgccggcgag gcccagcgcg gcgccgatga cgaccgcgag gaccgtacgg gggatccgct
    25261 tcgtggccgc cgcctgcccc agggtctcgt cggctccgcc gagcgccgcc tggacgtcgg
    25321 cccaggggac gtcgcgcgag ccgaacgcga cggacgccac catgacggcg gccaggagga
    25381 ggacggcggc gaggagccag agcgtgcgga cgcccgccgg acgccgggcc atggaggcgt
    25441 ccggcgggcg ccggtcggtg acagcggtca cttgaccttg tccgcggcct tggcgagcgc
    25501 cgcggcgtag tcgtccagca cgtaaccgat cgacagcggc gtcgggttgg cggcggtggc
    25561 cagcggcgag ctgccgggca gcagataggt cgaactgcgc ttgacggcag ggatcttgga
    25621 gagcagcggg tccttggtga tcgccttgag caggtcgccc gtgtcgtcgc cgtagccggt
    25681 gatgatgtcc acgtcgtcga acgcgtcgat ctgctcggcg ctcttggtga gggcgaactt
    25741 cttcgtcccc tcggacgcct tcgcgatgct gcccggggtc gtcatgccca ggtcctcgaa
    25801 gaactgcgtc cgggtgtcgt gggtggtgta gaagccgatc tcgctgacgt cgttggggtc
    25861 gacgtgcgtc atgaacatcg ccgacttgcc cttgagctgc gggtacttgg cggcggtctt
    25921 cgctatgtcc ccgtccagct tcgtgatcag cttctcgccc tcgtcggcga ggccgatcgc
    25981 ctcgctgttg gtgcggatga tctcgcgcca cggggtcgcc caggcggcgt ccgggtaggc
    26041 gacgacgggg gcgatctcgc tgagggtgtc gtagtccttc ttggtcagcc cggagtaggc
    26101 ggcgaggatg acgtcgggct tggtgtcggc gacggcctcg aagtcgatcc cgtcggtctc
    26161 gtcgaacagc accggcgtct tggccttgag ctcggtcagc cgctcctcga cccagggcag
    26221 caccccgttg ccgtcgtcgt cgccgaagtt ggcggcggcc atgccgacgg gcacgacacc
    26281 gagggccagc ggcacctcgt ggttggccca gttgaccgtg gcgacgcgct tcggcttggc
    26341 ggggatggtg gtcttgccca gggcgtgttc gaccgtcagc gggaagccgc cggcggcgct
    26401 cccctcgccc ttcttgttcc cggcgtcacc gttgccgttc ccgccgcagg cggcgacgga
    26461 gacgagggcg gctgccacgg cgagcaggcg gaggcggtgt gaggacatgg gtgagtaccc
    26521 ggctttccgg aggtcggggt gccgcttccc gcacgtccgg gcatgggccg acgtcgtgga
    26581 gggtgcactg cggaggcaga gcggcttagg taaggcttgc cttcgtactt tatgagagtg
    26641 gacgcctgcg tcgcaatcaa ccgtttgaga cagtcgttgt agcgataggg acatccggaa
    26701 gtgccgctcg cgcccggtcg accgcccggc gtctcacccc gcccggaagg agcccggcgt
    26761 cagcccggtc gtccgccgga aggccacacc gaaggcgctc gccgagcggt agccgacctg
    26821 ttcggccacc gactcgacgt cccagccacg ggtcagcagg tcgatcgcgc gctgggcgcg
    26881 gaccgccgcg acccagcgga cgaagctcgt gcccgtctcg gcgctgaacg cgcgcgtgat
    26941 cgtccgggtg ctcacctcca gctcggccgc ccactccgcc agcgtccgct ggtcgcccgg
    27001 atcctcgcgt accgcgtccg cgacggggcg caggaggtcg gaggtgggga tctgcacgag
    27061 cagttcccgg ggtgagggcg cgaggacgtc gaggacgagc gcctcggtcg cggaccggga
    27121 ggagggggcg agtccgggtt cgccgagccg ttccagcagg aggcgcagca ggggggtgat
    27181 ctcgacggcg accggggtgt cggagatcga cgacgtcgtc cggaagccga agaagctcgc
    27241 gcggaaccag gtgcccgccg tcgccgatcc ggagtgcagg gtcccggcgg gcatccacag
    27301 gcccagggcg ggggtgatcg tccagatgcg ttcgccgacc accgccgagg aggcgccccg
    27361 ctcgttccag agcagttcgt ggaaggggtg ggagtgggcg tcccagaggg tgtcgtggga
    27421 gacgacctcg tcgtagggct ggatgacgaa gggggtgtcg accgatccgg gcgcatgcgc
    27481 cggcagcgat cgggtctccc tggtcatggg cgctcaggcc ttcctggtcg tacggtgcgg
    27541 cccccggccg tccgggggcc ggccgcggcg ggtgtctctc gcatccgccc agcctagaag
    27601 gtcgctccgg cgggtcccag ccgatgtcat cagctgctcc atcgcggctc cggaggccct
    27661 tcaccctccc ccggagcagc acctgcccgg tcgccccgtt ccccagcggc gacgaggcgg
    27721 ctccgctgac gcggtacgcg gacgccaggg ccgccctgtc cggcccccgg gctgagccgg
    27781 gagggactgg cctcgcggac gccgcacggg tgtcggacgg tgaggcggag gggattcgcg
    27841 gcagccccat ggccaaggcc ctcgacgacg aggggcatga gcgccggcgg tggatggcgg
    27901 gcagggggtt caccgccagg tgggcggcga cgctggagcc cggcatggag gccgtggcgg
    27961 accggatggc cgacggcatg ccggaccacg gctccccggc ggagctggtg gacagcctcc
    28021 ccacgtcctt ccgccggaac cccaccctgc gggccgccga ggaggggacc tcgtccccgt
    28081 caagtacgac gcggtcgtcc atggtctgcg cacgctgccc gtcatctggt ggcggcgccg
    28141 gggtccttcc gtacgggagg accggtcgcg ctcccggcgc ccgcaccggg gcgtgcggga
    28201 gcgtggcgtt ccgccgtctg cttcaactcg acgtttgcat gagggcagtt acgtccttca
    28261 ggtgaaaggg ctaccgcttt cgccgtgccc ggggctgttc ggccggacag ttgggtgggc
    28321 cgaccggact ccggtcggcg ggaccgtacg gtgaaaggtg acggattcat gaccactgag
    28381 gccacccggc gggtcgcgct cgtcttctcc ctgttcgatg ccaacgccaa cggggtcctg
    28441 gaggccgacg acttcgatct catggccgag cgcgtggtgc ggcaggcgca tgcgtcggac
    28501 caggcggcga aggacgcgat gcgcgcggcg ttccgtcggt actggacgac cctgctcacc
    28561 gaactcgacg ccgacgggga cggcgagatc agcttcgagg agttcaccgc ctgtgtgctg
    28621 tcgccggagc ggttcgacgc gacggtcgcc gtcttcgccg aggcgctggc cgcgctcggc
    28681 gacccggacg gcgacgggct gatcgagcgt cccctgttca tggcgctgat gacggcgatc
    28741 gggttcgagc ccgccaacat cgacgcgctc ttcgacgcgt tcgagccggc cgacggcgac
    28801 cggatccggg tggagacgtg ggtcgccggg atcaaggact actacgcccc cggaaaggcc
    28861 ggcatccccg gcgaccacct ggtcgtcggc accccggtct gaccggacgc ccccgcgtga
    28921 ccggacggtg gacgccccgc ccgcgagggg aggggcgtcc accgctcgcc gtccgcactc
    28981 agccggtcag caggtccggg tcgcccgcca gcgcggccag gcggccctgc gggtccggga
    29041 cgaggcggcg ttcggccaga tcgaggacgc cggccacccc ggtgatctcc gccgccaccg
    29101 agccgtcctc catgacgacc tgctgctcca gggtgaacgt cttccccgag ccgtactcga
    29161 agcggcaggt gacgcgtacc cgctccccgc cccgcagctc gcgcaggtac ttcacggtga
    29221 cctccagctg caccgggccg atcccgtcgg ccagcagctt ctcctgggga agcccggcgg
    29281 cccgcagcag ctcccagcgg gcgtgttcgg cgtactggag gtagacggcc tggttgaggt
    29341 ggccctgagt gtcgagttcg tagccgcgca cggtcacgtc aacggagaag gtcatgtccg
    29401 tgcgaacgcc tccgcccggc ggcccattcc ggcggaccgg tcctgcccga tccctttacg
    29461 ggcctgtcat gcaccggtaa cttccacccc gcaagagatt gcagcaacat tccggcagag
    29521 ctttctgccg gatcgtgtcc gctcgccgaa ccccgaggcg cgtcagggtt ctcccctccc
    29581 ctggagacac gtatgagacg cacccctcac cggctgtccg gacgcccgct cgcggcggcc
    29641 ctggcagccg gactgctggg actcctcacc tccgttccgc aggcggctcc cgccccggcc
    29701 ggcacccccg tcgcggccac ggccgccgcc gaggccacag cgaccgtctt ctactccacg
    29761 aagacccgca actggtcggc gtaccacctg cattacgccc tcgacggcgg ctcctggacc
    29821 accgtgcccg gcagccgtat gcagtccgcc tgcaccgact gggtcaagtt caccgtcccc
    29881 ctcggcggcg cgagcgggct gagagccgcc ttcaacaacg gctcgggcac ctgggacaac
    29941 aacgcgggcc gcgactacga cctgggcacc gggaacatca ccgtcaagga cggggtcgtg
    30001 gcgcacagcg acccgtgcgc gggcacgggc cccgaggagc cggaccccgg cgggccgaac
    30061 accgcctccg tctactacgc gacgtccacc gtcggctggt ccaccgtcaa cctgcactac
    30121 cgcccgcacg gcggagcctg gacggcggtc ccgggcgtcg gcatggaggc ggcctgcgcg
    30181 ggctgggtga agcggaccgt cgacctgggc ggcgccaccg gcctccaggc cgcgttcaac
    30241 aacggcaacg gggtctggga caacaacaac ggcggtgact acaccctccc tgccgggctc
    30301 accatcgtgc aggaccgcaa ggtgaccgcc acggcgaagg acccctgcgc cgccgaggag
    30361 ccggacaccg aggcaccctc cgtgcccacc ggggcgaggg ccgcggcgga cggggtgtcc
    30421 gtcctggtga cctgggaacc cgccaccgac aaccgggggg tgacgaaata tcaggtcaca
    30481 cggaccggcg gcacgaaggg caccctggtc accgatgccg gctccaccgt cctggccgac
    30541 accggactcg aggccaggac cgcctaccgc tacaccgtcc gggccgtcga cgccgccggg
    30601 aacgtctcgg ccgagtccgc cccggccacc gccaccaccg gtgagaagcc caccgcaccg
    30661 gcgacgggca caccgctggg caccgatccc cgcaaggacc ccatctactt cgtgctcacg
    30721 gcccgcttca acgacggcga cgccacgaac aaccgaggcg gcagccagca cgagaagtcg
    30781 ggcaacgcgg ccggcgacga ccccatgttc cggggggact tcaagggact ggtgcagaaa
    30841 ctcgactacg tcaaagggct cggcttctcc gcgatctgga tcacgccggt cgtcctcaac
    30901 cgctcggact acgactacca cggctaccac ggctacgact tctacagggt cgacccacgg
    30961 ctggagtcgg ccggcgcctc gtaccaggat ctcatcaacg cggcccacgc caagggcatg
    31021 aagatctacc aggacatcgt ccacaaccac tcctcgcgct ggggcgccaa gggcctgttc
    31081 accccgacgg cgtacggcgt ccgcgactcc cagtggagcc ggtactacga cgagaggaac
    31141 gacggcttcg cgtacgacgg cctcaccgtc gagcccaagt cggggaagtc gtactacaac
    31201 ggcgacctgt ggtccacggc cgagccgtcc ggcaacacct gcgtaggctg gggcacaccc
    31261 accgggcaga cctcaccgga ggggtaccgg atctacaact gccagtggcc gagccccact
    31321 tcggggatgt tccccaaggc gctctaccac aactgctgga tcgggaactg ggagggcgag
    31381 gactcccgct cctgctggct gcacgacgac ctcgccgatc tcaacaccga gaacgcccag
    31441 gtgcagaact acctgatcgg cgcgtacaac aagtacatcg acatgggcgt cgacggcttc
    31501 cggctcgaca cggcggtgca catcccccgc accacctgga accgccgctt cctccccgcg
    31561 atccaggagc gggtaaccca gcggttcggc gccgaggcgg cgcggaactt cttcgtcttc
    31621 ggcgaggtcg ccgccttcgt caacgacaag tggaaccgcg gatcggtcaa ccactccgcg
    31681 cagttcttca cgtggaagga gcgcaaggag tacagcgcgg acgacgagaa ggccgccctg
    31741 gagatgtacg gctacgagca gcagcagggc acggcggccc agcccgtatc cgacaacgcc
    31801 ttcctcaggg ggaacgccta ccacgcaccg gaccgcagcc ggttctccgg gatgaacgtc
    31861 atcgacatgc ggatgcacat gaacttcggt gacgcggaca acgccttcca caacggcaag
    31921 gactccgacg acagttacca cgacgccacc tacaacgtgg tctacgtcga cagccacgac
    31981 tacgggccca acaagagcag cgagcggtac gcgggcggca cggacgcgtg ggccgagaac
    32041 atgtcgctga tgtggacctt ccggggcatc ccgacgctct actacggctc cgagatcgag
    32101 ttccagaagg ggaagcggat cgactgcggg cccacgtgtc cgctggcctc gaccggacgg
    32161 gcgtacttcg gggaccggct ggccggtgag gtgacggcgt ccgatttcgg caaggtggcc
    32221 tcggccaccg gcaaggtcgc cgacacgctg gccgcgcccc tggcccggca ccttcagcgg
    32281 ctcaacgaga tccggcgcgc gatccccgcg ctccagatgg gccagtacgc gacggagggc
    32341 atcagcggct ccatggcgta caaacggcgc tacaccgaca cggcgagcgg caccgacagc
    32401 ttcgccctgg tgacggtctc cgggagtgcc acgtacaccg gcatccccaa cggcacgtac
    32461 caggacgccg tgacgggtga caccaaggtg gtgagcggag gcacgctcgc ggtcccggcc
    32521 cccgggaagg ggaacctgcg cgtgtacgtc ctggacctcg gcgggaagaa cgccgcgccc
    32581 gggaagatcg gcgctgcggg cccgtacctc aagtagccgc ctcacccggc gacccgccgc
    32641 accgtgcgca gcaggtactc cctgcggtcc ggcgggtcgt ggtcggtgcg cgggcggtcc
    32701 ggagtcgggc cggtcaccgg gcggtggccg tcggacgcgg actccaggac cccctcggcg
    32761 cgggtcgccc cgggcagcgg ggtcgtcacg ccgtcggtca ggcggttgtg gagggccgca
    32821 accggtttcc cttcccgtgc agatgcggaa agcgccattc ggtgcggctg cgcagggttt
    32881 cgccggggcg cagcacggtg ctggggtggg cggggtggtt gggtgagtcg ggcaggtgct
    32941 gggtctccag gcagagcgag ccgtggcgtt cgtggcggcg gccggtgccg tcggtgaacg
    33001 cgctgtcgag ttggttggcg gtgtagacct ggagccccgg ttcggtggtc cacagctcca
    33061 gggtgcgccg gtcgccgggg gcggtgaggc gggcggcgcg gcggagggtg ccgggggccg
    33121 cctcgcgcag tacccagcag tggtcgaagc cgccggccag ggcgagttgg gggtgggggc
    33181 gggagagggc gttccgtatc ggctgcgcgg tggtgaggtc gaagggggtg ccggtgaccg
    33241 gggccggcgg gccttcgggg atggagcccg cgtcgacggg gaggtagtcg tcggcatcga
    33301 cctggagggt gtggccgagg atgtcgtcgg cgccgaggtt gaggtaggcg tggttggtga
    33361 ggttgacgac ggtgggccgg tcggtgacgg ccgtgtactc cagggcgagc gtgccggtgg
    33421 tgtccagggt gtaggtggcg gtgacgtcga gtgcgccggg gaagcccatg tcgccgtcgg
    33481 ggctgtgcag ggtgaggcgg aggacggcgg cggagtccgt tcggtcggcg gtggcctgcc
    33541 agaccttggt gtggaagccg tccgggccgc cgtgcagggc gtggccccgg tcgttggcgg
    33601 ggatgtggtg cgtggtgccg tcgagggtga agcggccgtg ggcgatgcgg ttggcgtacc
    33661 ggccgacgat cgccccgaag taggggttct tgtcggtgta gtcgtcgagg gcgggcagcg
    33721 agcggacgac cgggccgggg gcgccgtcgg tgtccggcac ggtgaggctg tgcaggacac
    33781 cgccgtaggt gaggatcccg gcccgtacgc cggtgccgga gtccagggtc cagaggtcgg
    33841 tgtcgctctt cccgtgggcg cggccgaacg gtttgcggtg cacggtgggc atgaggagtc
    33901 cttgggggtg cggacgacgt ctagcgggag tggcggggtc cggtggattc gcggaggacg
    33961 aggcggtagc cggggcgggg ccgccggggt tcggcgaccg gggtgccggc gaggcgttcg
    34021 acgaggctgt cgacggcgag ccgggcgatg gccgccttgt cgggcgcgat ggtggtgagg
    34081 gtggtggacc cgtaccggct ctcctcgatg tcgtcgaagc cgacgacggc gatgtcgccc
    34141 gggatggtca ggccgcgctc ggtgatggtg cgcatggcgc cgatggcgat catgtcgttg
    34201 tacgcgaaca cggcgtcggg ccgctcgccc cggtcgagga gcgaggccat ggcggcggcg
    34261 ccgtcctccc tgccgtagcc gtcggtgacg acgacgaggg actcgtcggg ggtgatgccg
    34321 gaggcggcca gctcctcgcg ccagccgcgc aaccggaggt gggcgggctg gcgttcctgt
    34381 ccggtacggg agccgaggaa ggcgatccgg cggtggccgt gggcgatgag gtgggcgacg
    34441 gcctcccggg cggcggccac gttgtcgatg gcgatgtggt cgtacggggc ctcgtactcc
    34501 cgctccccca gcagcaccag cggcgccgtc tccgtccggg ccatcaggtc ctcggtctcc
    34561 aggtggatgg ggctgaggat gagtccgtcg atgacatggg accggaaccc ctggctgacc
    34621 agcagctcct tctcgcgcag acctccggtg tggtcgacca ggaccgtgta gtcgtgccgg
    34681 gcggcggcgt cgacgacctc accggccagc tccgcgaagt acgggttgcc gaactcgggt
    34741 acggccagcg cgatgatgcc ggtgcggccc ttgcgcagat ggcgggcggt gaggttcggc
    34801 cggtagccga gctcgtcgat ggcctgctgc accttggccc gcatcttggg ggtgacgtgc
    34861 tggtagttgt tgaccacgtt cgacacggtc ttgatggaca cgcccgcccg ttgagctacg
    34921 tccttgaggc tgacgcccac ggcactcctt gtactcggtt cgactcgtcc ctgcccggtc
    34981 cgcctggtcc gtccggttca ggtggttctc cggctgcgcg cgaggtaacg ctgcgccacc
    35041 acgacaacga taaggaagcc gccgctgacc accgattggt acgaggagtt gagcgagccg
    35101 atctggttga tgaggttctg gatcacggcg agcagcagga cgccccagag ggtcccgctg
    35161 atcgatccgg cgccgccgat gaggagcgtg ccgccgatga cgacggcgga gatcgcgtcc
    35221 agctccatgc cgacgccgac gatggtgacg ccggaggaga ggcgggcggc gttcagcgct
    35281 ccggcgagtc cggcgagcag tccgctgagc gtgtagacga ggatcttcgt acgggcgacg
    35341 ggcaggccca tcagggtggc cgcgtcgctg ctgccgccga cggcgaacag ggtctgcccg
    35401 aacgaggtcc gctggagcag cagtccgccg acgccgaaga ggacgagggc gacgaggatc
    35461 gggtggccga agccccagac gctgccctgg ccgagttcgg cgaacgcgga gtccttgggg
    35521 acgaggtagg tggtggcgcc ctcgtcggtg aaggcgagga ggatgccgcg cgccgcgagg
    35581 agggaggcga gcgtgacgat gaagggtgcc atgttcgcgc gggcgatgag gaggccgttg
    35641 accagcccga tcgcggagca gaccacgagg gggacgagca gcgcggcgag gaagccccac
    35701 tgcgaggccc aggccgccag gactcccccg agggcgaaga cggagcccac ggagaggtcg
    35761 atgccaccgg tgatgatgac cagcgtcatg ccgagggcga cgatcgcgag gaacgatgcc
    35821 tggacggtga cgccccgggc attgtcgacg ctggcgaagg tcggatagac gaacgaggcg
    35881 atgaggatca cggtcagcag gaccgcgagg acgccttgcc gctggacgag ttcgccgata
    35941 cgggagccgg tggagcgctc gggccggggc tcggggcggg agggcgtgtt cttgaggggc
    36001 gccggcacct ggggggccag ggcggcgggg gtggtgttct tcatcgggac cgacgctccc
    36061 gggcgacgta gacggcggcg atgatgatgg ccgcctgggc gatctgtgcg gtggagtcgg
    36121 gcaggtcgtg cttgacgagg gtggcgcgca gcagctgcat cagcagggcg cccgcgacgg
    36181 tgccgagcac ccggatggag cccccgttga gcggggtgcc gccgacgacg acggccgtga
    36241 tggcggagag ctccatgagg gtgccgagcg aggacgggtc gctggcggtg agccgggcgg
    36301 tggcgaggat gccggcgagc gcggccatcg tgccgcagag gacgtagacg ccgatcagaa
    36361 cgcgtttgac gggcagtccg gacagtccgg cggcggcccg gttgccgccg atggcgacga
    36421 tctggcggcc gaaggtggtg cgctgcacca ggaacgcgac ggccagcgcg agcacgcccg
    36481 cgatgaggac gacgagcggg atgccgagga aggagccggt gccgagcgcc aggatgtcgg
    36541 ggttgacgat ctgcttgagc tggccgtccg ccatcaccag ggccaggccc cggccgccga
    36601 cgaacagggc gagggtcgcc acgatgggtt gcagcccgac gagcgagacg agcgtcccgt
    36661 tgatcgcgcc gaccaccgca ccggcgagca gcgcgatcag gagcgcgggg accaggccgt
    36721 agccgaggta gagcggcagc agggcggcgg cgagcgccat ggtggagccg acggagagat
    36781 cgatgccctc ggtgccgatg accagggcca tgccgagcgc gacgatgacg atgggggcga
    36841 cctggacgag ctgggtgcgc aggttgtcgg ccgtcatgaa gtgctcggtg aacagggcgt
    36901 tgaagagcag gacgacggcg acggccgcgt acacgccgta ctcctggtac caggcggggt
    36961 cgcgcagccg ggccagtggc ttcgcggggc gtggcagggt ggcctggggg gtggtcatcg
    37021 ggggtcctcc tggccgttcg ccggggcttt cccgtcggcg tcggcctcgt ggctgcggtc
    37081 ggcgggctcg gcggcgggcg tgtggtcggc gagcacttcg aggaggcggc tctcctccac
    37141 ctcgtcaccg gcgagttcac cggcgacggc gccgccgcgc agcacgacga tgcggtcggc
    37201 gccctcgatg agctcctcga tgtcggagga gatcagcagc acggcgaggc cttcgcgggc
    37261 gaggtcgtcg atgaggctct gcacctcggc cttggcgccg acgtcgatgc cccgggtcgg
    37321 ctcgtcgagg agcagcacct tgggttccag acagagccac cgggcgagga gtaccttctg
    37381 ctggttgccg ccggagagtt cgccgacctt ctgctcgggg ctggaggcct tgatcctcag
    37441 ccgctccatg aagatgtcga cgatgcggtc ctgcttctcg cgggagacga tcccggcgcg
    37501 ggagagccgg ggcatcgcgg cgagcacgat gttctcgcgc acggagagct gggggatgat
    37561 cccttcggcc ttgcggtcct ccgggagcat gctgatgccc gcgcggatgg cggcggccgg
    37621 ggtggggcgg ccgatgcgct tgccgtcgac ggtgatctcg ccgccgtcca gggacagcgc
    37681 gccggtcagc gccttggcgg tctcgctgcg cccggagccc agcagcccgc cgagtcccag
    37741 cacctcacct ccgtacagct ggagggatat gtcgtgcagt tggtggcggc ggtcgaggcc
    37801 ggtggcggtg aggacggggg tgcgggccac gtcgtgcccg gcggcgtcga agctggtgag
    37861 gccctcgcgg cggacctcgg cgaggtcgcg gccgagcatc atcgagacga gccgcatccg
    37921 gtccaggtcg gccaggtcgc cggtgtggat gtggcggccg tcgcgcagga cggtgacccg
    37981 gtcgcagatg cggtagagct cgtccatgcg gtggctgacg tagaggacgg cgatgccctg
    38041 gccgcgcagg ttctcgatga cccggaagag ggtctcgacc tcgcggggct ccagcgagga
    38101 ggtgggttcg tccatgatga cgacctgcgc ctgtacggag acggcgcggg cgagggccac
    38161 catctgctgg gtgccgatcc ccagggtgtg cagggggcgt ttggggtcga cgcggacgcc
    38221 gaaaccgtcg aggagttcgg tggtctcgcg gttcatccgg gcgaagtcga tgaggccgaa
    38281 acggttcttc ggctcgcggc ccaggaagat gttgcgcgcc acgctcatca gcgggacgag
    38341 gttgacctcc tggtagatgg tggagatccc ggcctgctgc gcctcgaagg gccgggcgaa
    38401 gcggacgggc tcgcccgcca cccgtatctc gccgtcgtcg ctctggtaga cgccggtcag
    38461 caccttgatg agggtggact tgccagcccc gttctcgccg acgagcgcgt gggtctcccc
    38521 ggcgcgcagc gagaaggaga cgccgtccag ggcgacgacg ccggggaacc gcttgctgac
    38581 cgagcgggct tcgagcacgg gttccgcgac ggcggtctcc gcgtgccggg gtgtcgcttc
    38641 ggtgggtgcc atggatcctg gccttccggt gttacgggaa tggggccggg ccgccgtgag
    38701 cgccgggggc gtcgcggcgg ccggccgtcc ggtcggggtc agtaggctcc gccgagcgag
    38761 tccttggcgt tggcctcgtc gtactcccgg tcggtgatga tgacgttctc ggggatctcc
    38821 tcaccggcgt agaacttctg cgcggtggcg aaggcgagcg ggccgaagcg cgggttggac
    38881 tcgatgaccg cgttgtactc gccgttggcc agggcctgga cggcgttgcg ggtgccgtcg
    38941 accgagacga tcttgacgtc cttgccgggc ttcttgccgg ccgccttgat cgcggtgagg
    39001 gcgccgaggc ccatctcgtc gttctcggcg tagacggcgg tgatgtcggg cttggactgg
    39061 atgagctgct ccatgacctg ctggcccttg tcgcgggcga actcgccggt ctgctgggcg
    39121 acgatctcca ggccgggcgc ctcggccttc acctggtcga cgaagccctt ggtgcggtcg
    39181 gtggtgacgt tgttgccgga ggcgccgagc aggatcgcga ccttgccctt gccgccggtc
    39241 accttgatca tcgcatcggc ggcgcgcttg ccctgctcca cgaagtcgga gccgaggaag
    39301 gccacatagt ccttgcaggc ggtggagttc accttgcggt cgatggtgag gaccggcacc
    39361 ttcttggctg ccgccgcctt caaggcgggc tccagaccgt cggagttgag cggcgcgacg
    39421 atgaggaact gggcaccctg cgacagcatg tcctggatgt cgctgatctg cttggagagc
    39481 tgggactgcg cgttggtggt gaggagcttc ttcacgccga tcttcttcgc ctcgtccttg
    39541 atggactggg tctcggcgat ccggaacggg ttggcctcct tctccgactg ggagaagccg
    39601 accacggcgt tcttcaggtc cagcttcggc gcgccgtagg tctccagcga gcagcccgaa
    39661 ccggaggtgg agtcggggga cttggcttcc tgggcaccct ggctgctgtc gccgcccgcg
    39721 ttgttcgagg tctccgactt ggcgcagccg gcggcggcca gcgtggcggt ggcggcgagg
    39781 aggcaggcca cggcgagggt acggggtcga cgctggatca tcatgcgcgg aacgctcctt
    39841 ggcgggttga cggcacgcgc ggcggcgtgc ggtcgggcat gcgggacgag gcatgggccg
    39901 cgcggcggct gctgccactg cactcctcac gaccctgctc cgacgtgcgg gaacagcggc
    39961 cgcgagagcc tgctcgggct gtcggcggct cggtttacaa cgttatatat gcggtgcggc
    40021 acgggcggca agagtggggc cgatgcgttt ccaaaatgtg tcggccaccc ggcggggcgc
    40081 ccgcgcggga tacccacggc catcggcccg ccctacggca acgggtcctg cgcaccccct
    40141 ggacagccgc ccggcaccgt gctgtcatac cgccggacgc catatttcca acgttgcaag
    40201 aacggatgcc gtacgccgga ccgcccgcgc gacggcgacc ttcggcgtgt gctcgccgca
    40261 cgttcgctcc tcgcgcccga ccggccgccc cgccgctccc ccggccgggc ggccgcgcac
    40321 cacgccccgc gcaccacgca ccgcacgtct cgccctgcac cagcccgcgc acccgcaccg
    40381 cgcgcggcca ccacccccac cgagccggcc gcagctcagg cggtcccggc tcagagcagg
    40441 agccgtaccg atgcccctga accgcaggca gctcatcacc accgccgtgg ccaccgccgt
    40501 ggccaccggt acggcgagcc gatgggccac cgccgcgaca cccgagcgcc accgggtggc
    40561 agcggccccc ggcggccact actcccccaa cgccgcgccc ctgcacccga ccgcgttcct
    40621 caagctgccg ccgggcaagg tgaaggcgcg cggctggctg gccggtcaac tccggctcca
    40681 gctggagggg ttgtgcggcc ggtacgagga gttctcgcac ttcctggact tcacggcgac
    40741 cggctgggtc cgccccgacc gtggcggctg ggaggaagtc ccctactggc tcagggggta
    40801 cgccgacctc gcgatcgtca ccggggacac ggccgcgctg gccaccaccc gccgctggat
    40861 ggacgcgatc ctcgccaccg ggcagagcga cggcttcttc ggcccgaagg cactgcggac
    40921 ctccctcaac ggcggccccg acttctggcc gttcctgccg ctgatccagg cgctgcgctc
    40981 ctggcaggag tacagcggtg acacccggat catccctttc ctcagccgct tcttccgcta
    41041 tatgggggcc cagggtcccg gcgccttcga ctccagttgg atcgccctgc gttggggcga
    41101 cggcctggac agcgcgatgt ggctctacaa ccgg
//
