LOCUS       NZ_QZFU01000036        21020 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Nocardia panacis strain YIM PH 21724 NODE_5, whole genome shotgun
            sequence.
ACCESSION   NZ_QZFU01000036
VERSION     NZ_QZFU01000036.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia panacis
  ORGANISM  Nocardia panacis
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 530053)
  AUTHORS   Miao,C.
  TITLE     YIM PH21274 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 530053)
  AUTHORS   Miao,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2018) Yunnan University, Yunnan Institute of
            Microbiology, 121, Kunming 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 29.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003598715.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 03:06:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,880
            CDSs (total)                      :: 6,804
            Genes (coding)                    :: 6,707
            CDSs (with protein)               :: 6,707
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 32 of 97
            Pseudo Genes (incomplete)         :: 82 of 97
            Pseudo Genes (internal stop)      :: 7 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:26:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 370306
            Orig. end                         :: 391326
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QZFU01000036.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21020
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21020
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21020
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11020](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11020)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(163..1617)
                     /locus_tag="D5S18_RS27230"
                     /old_locus_tag="D5S18_27220"
     CDS             complement(163..1617)
                     /EC_number="1.2.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018177460.1"
                     /locus_tag="D5S18_RS27230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27220"
                     /product="NAD-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="WP_120043934.1"
                     /sec_met_domain="Aldedh (E-value: 3.9e-159, bitscore:
                     524.9, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRERADLLAAVPRGLWLGGEQVPATGGGAFPVHDPATGAVLTEVA
                     DATAADGAHALDAAAAAQPGWAATPARQRAEILRRAWELINARRDDFAMLMTLEMGKPL
                     AESYGEVTYGGEFLRWFAEEAVRINGRYTHSPSGAGRILVTKQPVGPALAITPWNFPLA
                     MGTRKIAPAFAAGCTMVVKPAAETPLTMLLLGEIFAEAGLPSGVLSILPTARAARLTDP
                     LFADARLRKVTFTGSTAIGKILLAQSASRVLRTSMELGGNAPFVVFADADLDAALDGAL
                     AAKMRNTGEACTAANRFHVDNAVRAEFTDRFTERMRALKIGAGHLDGVQVGPLISEEQR
                     DSVAELVADAVSKGARITTGGARVSGSGYFYEPTVLADVPAEARILREEVFGPVAAITG
                     FDGEAAGVAAANATEFGLAAYIYTTDLDRALRVAESVESGMVGINRGIISDVAAPFGGI
                     KESGLGREAGSEGIEEYLETKYIALP"
     gene            complement(1644..2993)
                     /gene="gabT"
                     /locus_tag="D5S18_RS27235"
                     /old_locus_tag="D5S18_27225"
     CDS             complement(1644..2993)
                     /EC_number="2.6.1.19"
                     /GO_function="GO:0003867 - 4-aminobutyrate transaminase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009448 - gamma-aminobutyric acid metabolic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (47-382). E-value: 1.1e-110.
                     Score: 361.8. Matches aSDomain:
                     nrpspksdomains_D5S18_RS27235_Aminotran_3.1"
                     /codon_start=1
                     /gene="gabT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005078063.1"
                     /locus_tag="D5S18_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27225"
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_120043935.1"
                     /sec_met_domain="Aminotran_3 (E-value: 5.6e-129, bitscore:
                     425.2, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDATHRLPQRRALVTPLPGPRSAALAARRDAAVAAGVGSTAPVY
                     AADADGGVLVDVDGNSFIDLGSGIAVTSVGASHPRVAAAVAEQAARFTHTCFMVTPYEG
                     YVRVAEQLAERTPGAHDKRSVLFNSGAEAVENAVKVARLATGRTAVVAFDHAYHGRTNL
                     TMALTAKNMPYKARFGPFAPEIYRMPMSYPFRDEPGLTGAQAARRAISRIEAQIGVDSL
                     AAIVIEPIQGEGGFIVPAPGFLAALADWARAHGVVFIADEVQTGFARTGAWFACEHEGV
                     VPDLIALAKGIAGGMPLAAVTGRADLMDAVHPGGLGGTYGGNPVACAAASATIAVMREL
                     DLPARAREIEVAVLPRLRELATETPVIGDVRGRGAMLAVELVRPGSTDPAPELAKAVAA
                     EALSQGVLTLTCGTYGNVIRLLPPLVIGADLLADGVGVLAEALRGCARRP"
     aSDomain        complement(1848..2852)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D5S18_RS27235_Aminotran_3.1"
                     /evalue="1.10E-110"
                     /label="D5S18_RS27235_Aminotran_3.1"
                     /locus_tag="D5S18_RS27235"
                     /protein_end="382"
                     /protein_start="47"
                     /score="361.8"
                     /tool="antismash"
                     /translation="DADGGVLVDVDGNSFIDLGSGIAVTSVGASHPRVAAAVAEQAARF
                     THTCFMVTPYEGYVRVAEQLAERTPGAHDKRSVLFNSGAEAVENAVKVARLATGRTAVV
                     AFDHAYHGRTNLTMALTAKNMPYKARFGPFAPEIYRMPMSYPFRDEPGLTGAQAARRAI
                     SRIEAQIGVDSLAAIVIEPIQGEGGFIVPAPGFLAALADWARAHGVVFIADEVQTGFAR
                     TGAWFACEHEGVVPDLIALAKGIAGGMPLAAVTGRADLMDAVHPGGLGGTYGGNPVACA
                     AASATIAVMRELDLPARAREIEVAVLPRLRELATETPVIGDVRGRGAMLAVELV"
     gene            complement(3068..4594)
                     /locus_tag="D5S18_RS27240"
                     /old_locus_tag="D5S18_27230"
     CDS             complement(3068..4594)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019510144.1"
                     /locus_tag="D5S18_RS27240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27230"
                     /product="APC family permease"
                     /protein_id="WP_120043936.1"
                     /transl_table=11
                     /translation="MSSTTTRNDAGPVGGKGLASGRIGTISGAILGISTVAPGYTLTTS
                     IGLIVAAVGLKMPAILIAGFIPMFLTAYAYRELNARMPDCGASFTWSAKAFGPYVGWMA
                     GWGMVMASAIVLSNLSAIGMKFGYLFLARISGYSELADVADNKVVNILTTLALLAAATY
                     VAGRGITTSERLQYVMVAFQLIVLLVFAVVALVKVTSGDAPAHLSFQFDWLNPFTGITV
                     SAFVIGVTGSIFAFWGWDTCLTLGEESKDPDRVPGRAGLLCVVSILITYLLVTIAVMMY
                     AGVREDGVGLGNPHNADNVFAVLADPVLGPAGPLLLLAIFASAVASLQTTFLPVARTLL
                     AMGVYGAFPKRFAVVRSRTQAPVFGTIVVGVVTGVFYTAAALLSQRVLVDTVAALGIMI
                     CWYYGITAFACVWYFRRELFTGARNFVFKFLFPLSGGLMLAAVFVTSVRESMNPAKGSG
                     ASIGGIGLVFYMSFGILLLGAVLMLVMRWRQPQYFRATQAALAPDPRTAL"
     misc_feature    complement(3341..3343)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4682..6112)
                     /locus_tag="D5S18_RS27245"
                     /old_locus_tag="D5S18_27235"
     CDS             complement(4682..6112)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007301177.1"
                     /locus_tag="D5S18_RS27245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27235"
                     /product="gamma-aminobutyraldehyde dehydrogenase"
                     /protein_id="WP_120044097.1"
                     /sec_met_domain="Aldedh (E-value: 8e-152, bitscore: 500.8,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPVLENYIDGAFVASGATETLELVNPVDESVLARSPISTGADV
                     DAAMRAAERAFASWGRTTPSVRQKALLRLADAVEAHSAEIVAAQCRNTGQPAAVVAAEE
                     VAVGADQLRFFAGAARLLEGRAAGEYLEGFTSYVRREPIGVVAQVTPWNYPFMMAIWKI
                     GPALAAGNTIVLKPSDTTPESTLVLAGISKGILPDGVLNVVLGDANTGAELVRHPTPGL
                     VSITGSVRAGIAVAGSAAQQLKRAHLELGGKAPAIVFPDADLEKAALGIAQAAFFNGGQ
                     DCTAATRLLVHESIHDEFVAAVAKCAEQLRPGLPDDPDSFYGPLNNRGHFDAVLGKLAA
                     LPAHVTVVTGGKRLGDKGFFVEPTIVTGVRQHDALVQEETFGPVLTVQPFTDAEHAIAL
                     ANDVRYALASSIWTGNHAIAEKFTRALDFGAVWVNCHIPLVAEMPHGGFKYSGYGKDLS
                     AYSVEEYTRIKHVMSAHD"
     gene            6247..7758
                     /locus_tag="D5S18_RS27250"
                     /old_locus_tag="D5S18_27240"
     CDS             6247..7758
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018161736.1"
                     /locus_tag="D5S18_RS27250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27240"
                     /product="PucR family transcriptional regulator"
                     /protein_id="WP_120043937.1"
                     /transl_table=11
                     /translation="MFVSIEWVLAQPEFAARLRGGAAGLRRGIDLVVTSELEDPCRWLS
                     GGELVLTTGMRLPDTPERRAAYLRELDQCGVAGLGFGIGLTHAEVPRDLVRAADAIGLP
                     LLEVPLRIPFAAIVKRVSARIAELRYDAVLRAAAAQPRMTRALIRSGAHAIVAELARSL
                     AATVLVLDPAGEVIEYRPGPPDPELMRAARAATGTAAGGVRTEPSGASITHQRIGVGRQ
                     HHGDLVVISPTALGHVDQILLGHANSLLALDFEKPARLQDARHRLNSQALALLLGAETD
                     PEPAWTQLAQAADAAGRIRVLAVDCDTAEAAEEARNAIEDAVIRAGHPLFLHCDASELL
                     AVLPASGAALAQRSAHDIVGGARRFLRFGLGRAHPVRELATAVSGARLAASAATRGGPA
                     AEFGTPTGESLLSHDATRQLLATMAATLLAPVIDHDRTHATPLLPTLRAYLEGNGHWES
                     AAACLGIHRHTLRNRMTTIRHLLSCDLDDARIRAELLLTLLAADH"
     misc_feature    6260..6275
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.75"
                     /tool="antismash"
     misc_feature    6574..6576
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7900..8379
                     /locus_tag="D5S18_RS27255"
                     /old_locus_tag="D5S18_27245"
     CDS             7900..8379
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014985312.1"
                     /locus_tag="D5S18_RS27255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27245"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_120043938.1"
                     /transl_table=11
                     /translation="MSEQEVNRTAAPVLDPINKRIIAQLQEDGRRPYAAIGKAVGLSEA
                     AVRQRVQRLSDAGVIQIVAVSDPLQVGLFRQAMIAVTVDGPLGPVAEALAAMDEITYVV
                     ECAGRYDILCEAVCADDAALLDLVSNRLRGLPQVRHAEIMVYLKLRKQTYRWGSH"
     misc_feature    complement(7939..7952)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.39"
                     /tool="antismash"
     misc_feature    7972..7974
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8552..9934
                     /locus_tag="D5S18_RS27260"
                     /old_locus_tag="D5S18_27250"
     CDS             8552..9934
                     /GO_function="GO:0008483 - transaminase activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (37-387). E-value: 1e-91.
                     Score: 299.4. Matches aSDomain:
                     nrpspksdomains_D5S18_RS27260_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006367519.1"
                     /locus_tag="D5S18_RS27260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27250"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_120043939.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.2e-88, bitscore:
                     291.5, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTEQPATTERSARIIRDNMFLHFTPHTGLTGDDIPVIVRGEGA
                     YVYDAAGRRYLDGLAGLFAGQIGHGRDELAAAAARQTKELAYFPLWGYAHPTAIDLAER
                     LAEAAPGELNRAFFTVSGGESVETAWKLIRQYFKATGRPTKHKVISRSLAYHGTSMGAL
                     SITGIPGAKSEFEPLVPSTMRVPHTNFYRATEHADDYAAFGLWAADRIEEAIVFEGAET
                     VAAVFLEPVQNTGGCFVPPPNYFQRVREICDRHDVLLVSDETICAFGRIGYDFGAKRFG
                     YQPDLITTAKGLTSGYAPLGVVMLGDRIMEPFLNGSTFLHGSTYGGHPVSCAVALANLD
                     VIERENIYGHVLATEDAFRTTLEKLYDLPIVGDVRGTGYFYAVELVKDRTTKEKFTDED
                     ATRILKGHVSKALFEAGLHCRADDRAEPVIQLAPPLICEQAQFDEMEQALRFALTGAQE
                     LL"
     aSDomain        8663..9712
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D5S18_RS27260_Aminotran_3.1"
                     /evalue="1.00E-91"
                     /label="D5S18_RS27260_Aminotran_3.1"
                     /locus_tag="D5S18_RS27260"
                     /protein_end="387"
                     /protein_start="37"
                     /score="299.4"
                     /tool="antismash"
                     /translation="VIVRGEGAYVYDAAGRRYLDGLAGLFAGQIGHGRDELAAAAARQT
                     KELAYFPLWGYAHPTAIDLAERLAEAAPGELNRAFFTVSGGESVETAWKLIRQYFKATG
                     RPTKHKVISRSLAYHGTSMGALSITGIPGAKSEFEPLVPSTMRVPHTNFYRATEHADDY
                     AAFGLWAADRIEEAIVFEGAETVAAVFLEPVQNTGGCFVPPPNYFQRVREICDRHDVLL
                     VSDETICAFGRIGYDFGAKRFGYQPDLITTAKGLTSGYAPLGVVMLGDRIMEPFLNGST
                     FLHGSTYGGHPVSCAVALANLDVIERENIYGHVLATEDAFRTTLEKLYDLPIVGDVRGT
                     GYFYAVELVK"
     gene            complement(10001..11020)
                     /locus_tag="D5S18_RS27265"
                     /old_locus_tag="D5S18_27255"
     CDS             complement(10001..11020)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="D5S18_RS27265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27255"
                     /product="sesquiterpene cyclase"
                     /protein_id="WP_120043940.1"
                     /sec_met_domain="T1TS (E-value: 3.5e-70, bitscore: 232.4,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSRIDCGDLAVPLFVFPWEGSCHPAAEQAERDTVAWGAQYGLYP
                     DEKYRQRVVRTRYGYLAARCYPRADRALLQVTADYCLWFFLADDLFVDRVDTVTPDTIA
                     QLTAMIDVLDLDRVGERPIYGAAAWLDICRRLRMLLSPEHFQRFATGMRLWASTAGLQI
                     LNHVQPHPIRIGAYETIRRHTSGMNPCLALSDAANAGAVSAAEYYAPATQRLQLHANNV
                     VSWSNDIQSLVVEARQPGQFRNMVTLYTADGTDLSRAVDTVADRVRAEIDHFAVLAERV
                     RRSARTELCGYITGLQDWMRGYQDWYLLDTQRYGRAATEADDRAVAPGQRHERDRADH"
     gene            11244..12404
                     /locus_tag="D5S18_RS27270"
                     /old_locus_tag="D5S18_27260"
     CDS             11244..12404
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (29-380). E-value:
                     1.9e-42. Score: 137.6. Matches aSDomain:
                     nrpspksdomains_D5S18_RS27270_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019925407.1"
                     /locus_tag="D5S18_RS27270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27260"
                     /product="aminotransferase"
                     /protein_id="WP_120043941.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.6e-41, bitscore:
                     137.5, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.4e-13,
                     bitscore: 44.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLNPETVSVIDSPIGSAHKLVEKRSGARELLNLSQAAPQYPPAP
                     EVIEHIVATARDPHGAEYSTVGGLPHVRTAIAEDLATAYSGAVRPDQVVVTAGCNQAFC
                     LTVAALAGPGDEIIGYLPYYFNHDMWMRMTGLVPVYVDPGPELIPDVAATEAAITPRTK
                     AIVVVTPGNPSGFTVPPDRITELAEVAARHDLALIIDETYRSFRDTDAAPHRLLADPNW
                     TETVVSLHSFSKDLAIPGYRVGAVVSSTELGREVTKLLDCVAISAPRIGQEAAWAGLTA
                     AGAWRRARAAEIAQRRIWFTEAMAAHPGGYELLSAGGFFGWVRHPYPDRSTEDVVRELI
                     IDYDTLVIPGTVFLPDDRRMLRVSYSNADRDAIADFADRLTASAPH"
     aSDomain        11331..12383
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D5S18_RS27270_Aminotran_1_2.1"
                     /evalue="1.90E-42"
                     /label="D5S18_RS27270_Aminotran_1_2.1"
                     /locus_tag="D5S18_RS27270"
                     /protein_end="380"
                     /protein_start="29"
                     /score="137.6"
                     /tool="antismash"
                     /translation="ELLNLSQAAPQYPPAPEVIEHIVATARDPHGAEYSTVGGLPHVRT
                     AIAEDLATAYSGAVRPDQVVVTAGCNQAFCLTVAALAGPGDEIIGYLPYYFNHDMWMRM
                     TGLVPVYVDPGPELIPDVAATEAAITPRTKAIVVVTPGNPSGFTVPPDRITELAEVAAR
                     HDLALIIDETYRSFRDTDAAPHRLLADPNWTETVVSLHSFSKDLAIPGYRVGAVVSSTE
                     LGREVTKLLDCVAISAPRIGQEAAWAGLTAAGAWRRARAAEIAQRRIWFTEAMAAHPGG
                     YELLSAGGFFGWVRHPYPDRSTEDVVRELIIDYDTLVIPGTVFLPDDRRMLRVSYSNAD
                     RDAIADFADRL"
     misc_feature    12180..12182
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12437..12823)
                     /locus_tag="D5S18_RS27275"
                     /old_locus_tag="D5S18_27265"
     CDS             complement(12437..12823)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS27275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_27265"
                     /product="hypothetical protein"
                     /protein_id="WP_147404202.1"
                     /transl_table=11
                     /translation="MVSVSRPVLAFGVLGALASAVLGFAAPAQAATSIDIGAVGPANIA
                     VDYSCEPSSGVVAIRAMVGDPNADAPSADGTQTAVTCDGGTHNAIVGLVGTPVAAGQTV
                     QVRVALVDRDEIVVTGQAKLLSLA"
     misc_feature    complement(12782..12784)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(12851..12864)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            complement(12990..13949)
                     /locus_tag="D5S18_RS27280"
                     /old_locus_tag="D5S18_27270"
     CDS             complement(12990..13949)
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983953.1"
                     /locus_tag="D5S18_RS27280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27270"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_239004025.1"
                     /transl_table=11
                     /translation="MEISVMLDGMARGKDSPRPERAATAAEYVAALRSLKSWSGLAYRQ
                     LQGKAAANGDVLPSSTIATTLGRATLPRESFVAGFVRACGLDGEQVTRWLDARERIAAR
                     SREREDGVEPEPEPLVRRRFRFLWLLFAGIVGVLGTLGVQALSGKTDSGTPDPVPGLAL
                     PSIGSWALIQPARTPELCLSDGVDRTRHYPSVIAVQRPCAQTRVPRVYLEPVGGGMVRI
                     QWHHPSFGVGCLTVLRDGPGRDLLEPRGECASGDPTQRFRLEAVGPPAVGHFRLRPDAT
                     RECLSLRDQDMAAGAEVVQGRCSGGRDEEFLITLVPPA"
     misc_feature    14008..14023
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.27"
                     /tool="antismash"
     gene            14250..15407
                     /locus_tag="D5S18_RS27285"
                     /old_locus_tag="D5S18_27275"
     CDS             14250..15407
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="D5S18_RS27285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27275"
                     /product="cytochrome P450"
                     /protein_id="WP_203236935.1"
                     /sec_met_domain="p450 (E-value: 5.7e-14, bitscore: 46.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPRTAKTARAEIFRPLAPEMLADPYPVYARLRAEDPVHWHEGL
                     RALVLTRHADCTRVLREHGVFSADPRKLGKPIAAQVISLQTMDPPEHSIIRHHFVAALK
                     RRDLATWAAGVAATADELVAAVGTEPFDFVADIAEPLALSAMCLLYGVNYPLDDTVFRT
                     ASRTLALGMDAGLAPERRAPALAARETINEMIRQWVSDPPRHSVLAHLDDITAVPSEHL
                     VNSARAIFDAGYSTTANFLGNAVRWLLANGHRDALGTLDTRAVDELARLVGPVQAVSRL
                     CLEDTEFGGRSIGRGEIVIALLGAANHDPEVFPDPQRAEFGRAPNPHLGFGRGVHSCLG
                     SHIGNRIMVALSRSLASVRLESAGAHRQRPTATQRGLDLLPLRVR"
     gene            15407..16768
                     /locus_tag="D5S18_RS27290"
                     /old_locus_tag="D5S18_27280"
     CDS             15407..16768
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016289.4"
                     /locus_tag="D5S18_RS27290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27280"
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_203236936.1"
                     /transl_table=11
                     /translation="MRALLLALLLAALFAPAATAQDLAAENISRAVSTSDAMATVAALD
                     AIAVANGGNRETGKPGFARSREYVENALRRAGYDVVAQPVPYRDFAADTETLTAPDGRR
                     IRTLMAQFVPSGQVTGPLADAGAGCSTADYPKGTAIAVIRSGDCPSGDKTVAARDAGVQ
                     AVLVYDAGPAIDAAIRRQVPHAALPVGFLSQRDASALTAAPGSAQLELRGHTFDDTAVS
                     LFAETSGGHPDSVVMAGAHLDSAVDGPGINDNGSSVAALLETAIRLAPFQDRVPNKVRF
                     AFWGAEELIDIGSSYYIDTRTPAEVAAIALYLNWEMIGSPNYAHFVMDGDGADHPGGSA
                     GPPGSGTVKAVMAQGYQIQGVPYRTADLAQIGSDQEPFARAGIPIGGAFGGVRALKTPE
                     EAAVFGGVAGQPYDPCYHQPCDNLANVNPKAFEQALRAMAWAVARFAVDDHLKK"
     misc_feature    16757..16759
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16924..17658
                     /locus_tag="D5S18_RS27295"
                     /old_locus_tag="D5S18_27285"
     CDS             16924..17658
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016888784.1"
                     /locus_tag="D5S18_RS27295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27285"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_239004026.1"
                     /transl_table=11
                     /translation="MFSKVITDFWREQMFASAAIGANGDFAVTVNPDLKQDSGVMILEI
                     ADGATIATLAPALAAKIGLQSADAPTAAGFRKLLTDAEIALNGADFLFYFTEAAKSELL
                     AENNDSRVRRLTAEDAELFAAFESATPEQDLDDAYVELDHEIVYGSFDSGALVCAASSY
                     TWAAGDYTREKDSAISDFGVVTVPEHRGKGHARAAVRALARHAYAAGLEPQYRCQLDNA
                     ASVALAGKSGLTLFGNWDRIAD"
     misc_feature    16956..16969
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.07"
                     /tool="antismash"
     gene            17880..19148
                     /locus_tag="D5S18_RS27300"
                     /old_locus_tag="D5S18_27290"
     CDS             17880..19148
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="D5S18_RS27300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27290"
                     /product="MFS transporter"
                     /protein_id="WP_203236937.1"
                     /transl_table=11
                     /translation="MATQQTMVVAADAAQRRRITRTGAITAVILLLAYSIDYIDRFGIS
                     MALPAIGREFGLSKTSQGLLVTAFALVYMICQIPAGMVVDRIGSRALLLGALIMWSVFT
                     LMTAVTTTFALLLVVRGLFGASQGFFPAASFKTIAERTTPRNRGTVMSVVLAAAGVGSS
                     LSPLLMGPLLEHFGWRGAFLWLAGTGALLGVVLLLLLPKPLSIELRDAERPVPPSAKAR
                     RAVLRSPRVWLLAGVFCAANFVTYGLITWVPTYLQLAKGISIGKTGVLASIPMATSVFT
                     TIAGGFLFDRYFRDNPRWYLCVTLGIGGIFLIPMAAADSANAFIVWETCASFVAGLGSG
                     ALVALPMRLLPSTLTGTGMGVFNFGGQVAGVAAPLLLGIVMDKFSYAAAFGLLACSCLI
                     AAGLALCIPRRVDPTNFIKGALS"
     gene            19148..20653
                     /locus_tag="D5S18_RS27305"
                     /old_locus_tag="D5S18_27295"
     CDS             19148..20653
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF006560.0"
                     /locus_tag="D5S18_RS27305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_27295"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_120043948.1"
                     /transl_table=11
                     /translation="MHDNNGATTQSRTGEVLLRGGTVCDPGSGFSGTADVLVRDGKVAA
                     LGADLAVAADIPVLDVSAMIVGPGFIDLHSHVNSVAGQRLQAFDGVTTALELEAGAPDI
                     EQTYRAAAQDGRPLNYGYSASWAAVRYAAHLGTPPHDLLGVLGAPEWQRSSSDLERRTW
                     LDLLEKELAAGGLGVGILLGYAPRTDPAEFLAVARLAAQAGAPTFTHVRELVESDPTTP
                     IDGSTEIAVAAAETGAAMHHCHVNSTSRRHIDRVLSTLDTARASGSKVTVEAYPYAAGS
                     TAIGAFFLAPERLSRWGVGPSDIVLVDTGERIADAARLAAVREADPGAPCIIHYLDETS
                     AADIALLRNSLAFEDSIVASDAMFVTWADGSRESLHWPLPPNGRTHPRTSGTYAKSLRL
                     MVRESGAWTWLEAFRRCSYLPARVLDTICPTIRPKGHLGIGADADIVVIDPATVTDRAT
                     YADPTRTSQGIRHLMVNGTFVIRDNTLRTDAFPGRPLRASPLA"
     misc_feature    20815..20830
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(20864..20875)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
ORIGIN
        1 ggcggcccgc acctacgagt gggtcagcca acccggctgg ctctacacca atatcattcg
       61 cacatcatcg gttccgctga ttggacagac gacgatcgtc acgcgccgct cggacgtggc
      121 tactcgacag ccggtcgcac acacctcctg aaaggatgag aattacggca acgcgatgta
      181 tttggtctcc aggtactcct cgatgccctc cgagcccgcc tcgcggccca aacccgattc
      241 cttgatcccg ccgaacggcg cggcgacatc ggagatgatc ccccgattga tcccgaccat
      301 gccggattcg acggattcgg ccacgcgcag cgcgcgatcc aggtcggtgg tgtaaatgta
      361 ggcggccaaa ccgaattcgg tggcattggc ggccgcgaca ccggccgcct cgccatcgaa
      421 tccggtgatc gccgcgaccg gcccgaagac ctcctcacgc aggatgcgcg cctcggcggg
      481 cacatcggcg agcacggtgg gttcgtagaa gtagcccgac ccggacaccc gcgcaccgcc
      541 cgtggtgatg cgcgcgcctt tgctcaccgc atcggccacc aactcggcca ccgaatcgcg
      601 ctgttcctca ctgatcagcg gaccgacctg cacaccatcc agatgaccgg cgccgatctt
      661 cagcgcgcgc atccgctcgg tgaaccggtc ggtgaactca gcgcgcaccg cgttgtcgac
      721 gtggaaacga ttggcggccg tgcacgcctc gccggtattg cgcatcttgg ccgccagcgc
      781 gccgtcgagg gcggcatcca ggtcggcgtc ggcgaacacc acgaacgggg cattgccacc
      841 gagctccatc gaggtgcgca gcacgcgcga agccgactgc gccagcagga ttttgccgat
      901 cgcggtggaa ccggtgaagg tcaccttgcg cagtcgcgcg tcggcgaaca gcgggtcggt
      961 caaccgggcg gcgcgtgcgg tcggcaggat ggacagcacg cccgacggca gaccggcctc
     1021 ggcgaagatc tcgccgagca gcagcatggt cagcggtgtc tccgcggcgg gtttgaccac
     1081 catggtgcac cccgcggcga aggcgggcgc gatcttcctg gtgcccatgg cgagcgggaa
     1141 attccacggc gtgatggcca gcgcggggcc gaccggctgc ttggtgacca gaatgcggcc
     1201 cgcgcccgac ggggagtggg tgtagcggcc attgatccgg accgcctcct cggcgaacca
     1261 gcgcaggaat tcgccgccgt aggtgacctc accgtaggac tcggccagcg gtttgcccat
     1321 ttccagggtc atcagcatgg cgaagtcgtc gcgccgggca ttgatcaatt cccaagcgcg
     1381 gcgcaagatc tcggcacgct gccgggcggg ggtcgcggcc cagccgggct gcgcggccgc
     1441 cgcggcgtcc agagcgtgcg cgccatcggc ggcagtggcg tcggcgacct cggtcagcac
     1501 cgcgccggtc gccggatcgt gcaccgggaa ggcgccgccg ccggtcgcgg ggacctgttc
     1561 gccgcccagc cacagccctc tgggcaccgc cgccagtaga tcggcccgtt cgcgcatgat
     1621 gaaatctcct ctgtcggtgg tcgttacggt cggcgcgcgc agccgcgcag cgcctcggcg
     1681 aggacgccga caccgtcggc gagcaggtcg gccccgatca ccagcggggg cagcagccgg
     1741 atgacattgc cgtaggtgcc gcaggtcagc gtcagcacgc cctgcgaaag cgcttcggcg
     1801 gcaacggcct tggccagttc cggtgccgga tcggtgctgc cggggcgcac cagttccacc
     1861 gcgagcatgg cccctcgacc gcgcacatcg ccgatgaccg gcgtctcggt cgcgagctcc
     1921 cgtagtcggg gcagcacggc gacctcgatc tcccgcgccc gcgcgggcag atccagctcg
     1981 cgcatgacgg cgatggtggc cgaggcggcc gcgcaggcca ccgggttacc gccgtaggtg
     2041 ccgccgagtc cgccgggatg caccgcgtcc atcaggtcgg cgcgaccggt gaccgccgcc
     2101 agcggcatcc cgcccgcgat ccccttggcc agcgcgatca ggtcgggcac cacgccctcg
     2161 tgctcgcacg cgaaccacgc cccggtgcgg gcgaatccgg tctgcacctc gtcggcgatg
     2221 aacaccacgc cgtgtgcgcg cgcccaatcc gccagcgcgg caaggaatcc cggcgcgggc
     2281 acaatgaatc cgccctcgcc ctggatgggt tcgatgacaa tggccgccag cgagtccacg
     2341 ccgatctgcg cctcgatcct ggagatcgcc cgccgcgccg cctgcgcgcc cgtcaggccc
     2401 ggctcatcgc ggaacgggta ggacatcggc atccggtaga tctccggcgc gaacgggccg
     2461 aaccgcgcct tgtagggcat attcttcgcg gtcagcgcca tggtcagatt ggtgcgaccg
     2521 tgataggcgt gatcgaaggc caccaccgcg gtgcggccgg tcgccaagcg cgccaccttg
     2581 accgcgttct ccaccgcttc cgcgccggaa ttgaacagca cactgcgctt gtcgtgggcg
     2641 ccgggggtgc gctcggcgag ttgctcggcc actcggacat acccctcgta gggagtgacc
     2701 atgaaacacg tatgcgtgaa tcgggccgcc tgctcggcca ccgccgccgc cacccgagga
     2761 tgcgaggcgc ccaccgaggt caccgcgata ccggagccga gatcgatgaa cgaattgccg
     2821 tccacgtcga caaggacgcc gccgtccgcg tcggccgcgt aaaccggtgc ggtggaaccg
     2881 actccggcgg ccacggcggc gtcgcggcgc gcggccagtg ccgccgagcg cggtccgggc
     2941 agcggggtga ccagggcgcg gcgttgcggt agccgatggg ttgcgtcatg catttcgaag
     3001 gggtctccag gtcgagtcga aggggagaag atccgggtgg gaaaatcgcg tgacagcggg
     3061 tgcgaaatca cagcgcggtg cgtggatccg gcgcgagcgc cgcctgcgtg gcgcggaagt
     3121 actgcggctg ccgccagcgc atgaccagca tgagcaccgc gccgagcagc aggataccga
     3181 agctcatata gaacaccagc ccgataccgc cgatcgacgc gccgctgccc ttggccggat
     3241 tcatgctctc gcgcaccgag gtcacgaata cggcggccaa catgagtccg ccgctcagcg
     3301 ggaacaggaa tttgaaaacg aaattgcgcg caccggtgaa taattcgcgc cggaagtacc
     3361 agacgcaggc gaacgccgtg atgccgtagt accagcagat catgataccc agcgccgcga
     3421 cggtatccac cagcacccgc tgcgacagca gcgccgcggc ggtgtagaac acaccggtca
     3481 ccacgccgac cacgatggtt ccgaagaccg gagcctgcgt gcgggatcgc accacggcga
     3541 accgcttggg gaacgcgccg tacacgccca tcgccagcag tgtgcgcgcc accggaagga
     3601 aggtcgtctg caagctggcc acggcggagg cgaagatggc cagtagcagc agcggtccgg
     3661 ccgggccgag caccggatcg gccagcaccg cgaagacatt gtcggcattg tgcggattgc
     3721 cgagtcccac accgtcttcg cgcacaccgg cgtacatcat caccgcgatc gtcaccagca
     3781 ggtaggtgat cagaatggag accacgcaca gcagcccggc ccggccgggc acccgatccg
     3841 gatccttgga ctcctccccc agggtcaggc aggtatccca accccagaag gcgaagatcg
     3901 atccggtcac gccgatcacg aaggcgctca ccgtgattcc ggtgaacggg ttgagccagt
     3961 cgaattggaa gctcaggtgc gccggtgcgt cgcccgaggt caccttcacc agcgccacca
     4021 ccgcgaacac cagcagcacg atcagttgaa aggcgaccat cacatactgc aggcgctcgc
     4081 tggtggtgat gccgcgaccc gccacgtacg tggccgccgc gagcaatgcg agggtggtga
     4141 gaatgttcac cactttgttg tcggcgacgt cggccagttc ggagtagccc gaaatccggg
     4201 ccaggaaaag gtagccgaac ttcatgccga tggcggagag gttggaaagc acgatggcgg
     4261 aggccatcac catcccccac cccgccatcc agccgacata cggcccgaat gccttggcgg
     4321 accaggtgaa cgacgcgccg cagtcgggca tgcgcgcatt caactcgcga taggcgtagg
     4381 cggtcaggaa catcgggatg aacccggcga tgagaatggc gggcatcttc aacccgaccg
     4441 cggccacgat gaggccgatg ctggtggtca gcgtatagcc gggggccacc gtcgaaatgc
     4501 cgaggatggc accggaaatg gtcccgatac gaccggaggc cagccccttg ccgccgaccg
     4561 gccccgcgtc attgcgggtc gtggtgctgc taattgctct actctccttg cctcacaacg
     4621 gctttcgtcg accatgcggc gacccgaccg cccgatcggg ggtcgggtcg cgcggccgcg
     4681 ctcagtcgtg ggcgctcatg acatgcttga tccgggtgta ctcctcgacg ctgtaggccg
     4741 agagatcctt gccgtaaccg gagtatttga agccgccgtg cggcatctcg gccaccagcg
     4801 gaatatggca gttcacccat accgcaccga aatccagtgc gcgcgtgaac ttttcagcga
     4861 tggcatggtt gccggtccaa atactggacg ccagtgcgta gcggacgtcg ttggccaggg
     4921 caatggcgtg ctccgcgtcg gtgaacggct gcaccgtcag caccgggccg aaggtttcct
     4981 cctgcaccag cgcgtcgtgc tgacgcacac cggtgacgat ggtgggttcg acgaagaatc
     5041 ccttgtcgcc caggcgtttt ccgccggtga ccaccgtgac gtgcgcgggc agcgccgcga
     5101 gtttgcccag caccgcgtcg aaatggccgc ggttgttgag cggaccgtag aagctgtccg
     5161 gatcatccgg cagaccgggg cgcagttgct ccgcgcactt cgccaccgcc gcgacgaatt
     5221 cgtcgtggat cgactcgtgc accagcagtc gggtcgcggc cgtgcagtcc tgtccgccat
     5281 tgaagaaggc cgcctgcgcg ataccgagcg ccgccttctc gagatccgcg tccgggaaca
     5341 ctatcgcggg ggccttaccg cccaattcga gatgcgcgcg cttgagctgc tgggccgccg
     5401 acccggcgac cgcgattccc gcccgcaccg atccggtgat cgacaccagg cccggcgtcg
     5461 gatggcgcac cagctccgca cccgtattcg cgtcgccgag aacgacattc agcacaccat
     5521 cgggcaggat gcctttgctg atcccggcca gcaccaacgt gctctccggc gtggtgtcac
     5581 tcggcttgag cacgatggtg ttccctgcgg ccagcgcggg accgatcttc caaatggcca
     5641 tcatgaacgg gtagttccac ggcgtcacct gcgcgacgac cccgatcggc tcacgccgga
     5701 cataggaggt gaaaccctcc aggtactcac cggcggcacg cccttcgagc agacgcgcgg
     5761 cgccggcgaa gaagcggagc tgatccgcgc cgaccgccac ctcctccgcg gcgacgaccg
     5821 ccgcgggctg acccgtattg cggcattgcg cggcgacgat ctcggcactg tgcgcctcga
     5881 cggcgtcggc cagccgcagc agcgccttct gccgcacgct cggagtcgtg cgaccccagg
     5941 acgcgaaagc gcgctcggcc gcccgcatgg cggcgtcgac atcggcgccg gtggagatcg
     6001 gcgaccgcgc gaggacgctt tcgtcgaccg ggttcaccaa ctccagggtt tcggtggctc
     6061 cagaggccac gaacgcgccg tcgatgtagt tctcgagtac tggacccgac atgtattcac
     6121 cgtccatcca tccgactgtg atgcgcagtt tgtccggcca caagtgtgcg gtcccgcaca
     6181 ccacccctcc ccctgcctaa atgtccaacc acacaattcg gactcgccgt tttgtacagt
     6241 cgggcgatgt tcgtctccat cgaatgggtg ctcgcccagc cggaattcgc cgcccgactg
     6301 cgcggcggcg cggccgggct gcgccgcggc atcgacctcg tcgtcaccag cgaactcgag
     6361 gatccctgcc gctggctctc cggcggggaa ctggtgctca ccaccgggat gcgactaccg
     6421 gacacacccg aacgtcgcgc cgcctacctg cgcgaactgg accaatgcgg tgtcgccgga
     6481 ctcggtttcg gcatcggact cacccacgcc gaagtgccga gggatctggt gcgcgccgcc
     6541 gacgcgatcg ggctgccact gctcgaggtg ccgttacgga ttcccttcgc ggccatcgtc
     6601 aaaagggtca gcgcgcgcat cgccgaattg cgctacgacg cggtgctgcg cgccgctgcg
     6661 gcccagccgc gcatgaccag ggcgctcatc cgatccgggg cgcacgccat cgtggccgaa
     6721 ctggcccgat cgttggcggc gacggtgctg gtgctcgatc cggcgggcga ggtcatcgaa
     6781 tatcggccag gcccaccgga tcccgaactg atgcgggccg cgcgggccgc gaccgggacg
     6841 gcggccggcg gggtgcgcac cgaaccgtcg ggggcctcga tcacccacca gcgcatcggc
     6901 gtcgggcgcc aacatcacgg cgatctggtg gtgatcagtc cgaccgcact cggacacgtc
     6961 gaccagatcc tgctcggaca cgccaattcg ctgctggccc tcgacttcga gaagcccgcc
     7021 cgactgcaag acgcgcgcca ccggctgaac agccaggcac tggcgctgct gctcggcgcg
     7081 gaaaccgatc ccgaacccgc ctggacccag ctcgcccaag cggccgacgc ggcgggccgc
     7141 atccgggtgc tcgcggtcga ctgcgatacc gccgaggccg ccgaagaagc gcgaaacgcg
     7201 atcgaggacg cggtgattcg cgccggacac cccctattcc tgcattgcga cgcatccgaa
     7261 ctgctcgccg tgctccccgc ctcgggcgcc gcgctcgcgc agcgcagcgc ccacgacatt
     7321 gtcggcggcg cccggcgttt cctgcgtttc ggcctgggcc gcgcgcatcc ggtccgggaa
     7381 ctagccaccg ccgtctcggg cgccagactc gccgcctccg ccgccacccg aggcgggcct
     7441 gccgccgaat tcggcacccc caccggcgaa tccctcctgt cacacgacgc cacccgacaa
     7501 ctgctcgcca ccatggccgc caccctgctc gcccccgtca tcgaccacga ccgcacccac
     7561 gccacccccc tgctccccac cctgcgcgcc tacctcgagg gcaacggcca ctgggaatcc
     7621 gccgccgcct gcctcggcat ccaccgccac accctccgca accggatgac caccatccgc
     7681 cacctactgt cctgcgacct cgacgacgcc cgcatccgcg ccgagctcct gctgaccctc
     7741 ctcgccgccg accactgaac ccgccacgac ggatttcatg atcggctcgc gaaagtcgac
     7801 ggatttcgtt gttcgggccg ccgccggtcg ccgatggagc accgaacaca cccgccgagg
     7861 cgattgttcg gcgccgctcg gggcggcagg atgccggggg tgagtgagca ggaagtcaat
     7921 cggacggcgg cgccggtgtt ggatccgatc aacaagcgga tcatcgcgca gttacaggag
     7981 gacgggcggc ggccgtacgc ggcgatcggg aaggccgtcg ggctctcgga ggcggcggtg
     8041 cggcagcggg tgcagcggct ctccgacgcc ggggtgatcc agatcgtcgc ggtctcggat
     8101 ccgttgcagg tcgggctgtt tcggcaggcg atgatcgcgg tcacggtgga cggcccgctc
     8161 gggccggtcg ccgaggcgct ggccgccatg gacgagatca cctacgtggt cgagtgcgcg
     8221 ggccgctacg acatcctctg cgaggcggtc tgcgccgacg acgccgcgct gctggatctg
     8281 gtgtcgaatc ggctgcgcgg gctgccgcag gtccggcacg ccgagatcat ggtctacctc
     8341 aagctgcgca agcagaccta ccgctggggt tcgcactgaa caacgaaatc cgtagcaaga
     8401 tcgcagtgcg gcaactattt gtcgcggttg caagcccaga gacaaccgat tcggttgcac
     8461 atccggaaat agttgtggca taaacggagg taccgaaccc cggcgcagcg gccggggcgc
     8521 gattcggttc atccgctagg agtccgcaac catgaccgtc accgagcaac ccgccactac
     8581 cgaacgcagc gcgcggatca tccgcgacaa catgttcctg cacttcaccc cgcacaccgg
     8641 cctgaccggg gacgatatcc cggtgatcgt gcgcggtgag ggcgcctacg tctacgacgc
     8701 cgcaggacgc cgctacctcg acggtctggc gggtctgttc gcaggccaga tcggccacgg
     8761 ccgcgacgag ttggccgcgg ccgccgcccg ccaaaccaag gaactggcct acttcccgct
     8821 gtggggctac gcccatccca ccgccatcga tctggccgag cgcctcgccg aggccgctcc
     8881 cggcgaactg aatcgcgcct tcttcaccgt cagcggcggc gaatccgtcg agaccgcgtg
     8941 gaagctgatc cggcagtact tcaaagccac cggccgaccc accaagcaca aggtgatcag
     9001 ccggtcgctg gcctaccacg gcacctccat gggcgcgctg tccatcaccg gaatccccgg
     9061 cgcgaaatcc gaattcgaac ccctcgtccc cagcaccatg cgggtgccgc acaccaactt
     9121 ctaccgcgcc accgaacacg ccgacgacta cgcggcgttc ggactctggg ccgccgaccg
     9181 gatcgaggag gccattgtct tcgagggcgc cgagaccgtc gcggccgtct tcctcgaacc
     9241 ggtccagaac accggcggct gcttcgtgcc gccgcccaac tacttccagc gggtccgcga
     9301 gatctgcgac cgccacgacg tcctgctggt ctccgacgag accatctgcg ccttcggccg
     9361 catcggctac gacttcggcg ccaagcgctt cggctaccag cccgacctca tcaccaccgc
     9421 caagggcctc acctccgggt acgccccgct cggcgtggtc atgctcggcg accggatcat
     9481 ggagccgttc ctcaatggct cgacattcct gcacggctcc acctatggcg gacacccggt
     9541 ctcgtgcgcg gtcgccctcg ccaacctcga cgtgatcgag cgcgagaaca tctacggcca
     9601 cgtcctggcc accgaggacg ccttccgaac cactctggaa aagctctacg acctgccgat
     9661 cgtcggcgat gtgcgcggca ccggctactt ctacgcggtg gaactggtca aggacaggac
     9721 caccaaggag aagttcaccg acgaggacgc cacccgcatc ctcaaggggc acgtctccaa
     9781 ggccctgttc gaggcgggtc tgcactgccg cgccgacgac cgggccgaac cggtcatcca
     9841 gctcgcgccg ccgctgatct gcgagcaggc gcagttcgac gagatggagc aggcgctgcg
     9901 cttcgcactg acgggggcgc aggaactgct ctgaaccttc gaggtcgccg gggcgagatg
     9961 ggctgatccc gccgccgcgc ctcggtcgcc gcacgtgccg tcagtggtcg gcacgatcgc
    10021 gttcgtgtcg ttgtccgggt gcgacggctc ggtcatcggc ctcggtcgcc gcgcgtccgt
    10081 agcgctgggt gtcgagcagg taccagtcct gatatccgcg catccagtcc tgcaaaccgg
    10141 tgatgtaccc gcacaattcg gtgcgggccg accggcggac ccgctcggcc agcaccgcga
    10201 agtggtcgat ctcggcacgc acccgatcgg ccacggtatc gacggctcgc gacagatcgg
    10261 tgccgtcggc cgtgtagagg gtcaccatat tgcggaactg accgggttgg cgcgcctcca
    10321 ccaccaggct ctgaatatcg ttggaccagc tcaccacatt gttggcatgc aattgcagcc
    10381 gctgggtcgc gggcgcgtag tactccgccg cgctcaccgc ccccgcattg gccgcgtccg
    10441 acagcgccag gcacggattc atcccgctgg tgtgcctgcg aatcgtctcg taggcgccga
    10501 tccggatcgg atgcggctga acgtgattga gaatctgcaa acccgcagtg ctcgcccaca
    10561 gccgcattcc ggtggcgaaa cgctgaaaat gctccggcga caacagcatc cgcaggcgac
    10621 gacagatatc cagccacgcc gccgcaccgt agatgggccg ctcgccgact cgatcgagat
    10681 cgagcacatc gatcatcgcg gtcagttgcg cgatggtgtc cggcgtgacg gtgtcgaccc
    10741 ggtccacgaa cagatcgtcg gccaggaaga accacaggca gtagtcggcg gtgacctgga
    10801 gcagcgcccg atcggcgcgc ggatagcagc gcgccgccaa atacccgtat ctggtccgga
    10861 ccacccgctg ccggtacttc tcatcggggt agagcccgta ctgcgcaccc caggcgaccg
    10921 tgtcccgttc ggcctgttcg gcggcgggat gacacgaccc ttcccaggga aacacgaaca
    10981 gcggcaccgc gaggtcgccg cagtcgatcc ttgaccccat ccagccacgc taccagtatt
    11041 tccgaatacg aacagcccac tgccacaatg catttcagca ttccgatggg atcggtatcg
    11101 cacccgcggc atgcgggtgt cagagcgccg actcgtatcc gagaggcgcg gatcgaactg
    11161 tgcacggatt cgcgcgggta gtctcacccg tagccggaac cgcacccgcg tgcgggccgg
    11221 cgtccgcggc caaggagtag ttcatgcgtt tgaatcccga gaccgtctcg gtgatcgact
    11281 cacccatcgg ttcggcgcac aaactcgtcg agaaacgtag cggtgcacgc gaattgctga
    11341 acctgtcgca ggcggcgccg cagtatccgc ccgcgccgga ggtgatcgag cacatcgtgg
    11401 ccaccgcccg cgacccacac ggggccgaat actccaccgt cggcggactc ccccatgtgc
    11461 gcacggccat cgccgaagac ctcgccaccg cctactcggg tgcggtccgt cccgatcagg
    11521 tggtcgtcac tgcgggctgc aaccaggcat tctgcctcac ggtcgcggca ctggccggtc
    11581 ccggcgacga gatcatcggc tacctgccgt actacttcaa ccacgatatg tggatgcgga
    11641 tgaccggcct ggtgccggtc tatgtcgatc cgggtcccga gctcatcccg gatgtcgcgg
    11701 ccaccgaggc ggccatcacc ccgcgcacca aggccatcgt ggtggtgaca cccggcaatc
    11761 cgagcgggtt caccgtgccg ccggaccgca tcacggaact ggccgaggtg gcggcccggc
    11821 acgatctcgc gctcatcatc gatgagacct accgctcgtt ccgcgacacc gacgccgcgc
    11881 cgcatcggct cctcgcggat ccgaactgga ccgagacggt ggtcagcctg cacagtttct
    11941 ccaaggatct ggccattccc ggctaccgcg tcggcgcggt cgtctcctcg accgagctgg
    12001 gccgcgaggt caccaaactg ctcgactgcg tggctatttc ggcgccgcgc atcggccagg
    12061 aggccgcctg ggccggactc accgcggcgg gcgcgtggcg gcgcgcacgg gccgccgaga
    12121 tcgcccagcg ccgcatctgg ttcaccgagg ccatggccgc gcatccgggc ggctacgaat
    12181 tactctccgc cggcggattt ttcggctggg tccgccatcc ctatccggac cgctccaccg
    12241 aggatgtggt gcgcgagttg atcatcgact acgacaccct cgtcatcccc ggcaccgtct
    12301 tcctccccga cgaccgtcga atgctgcgcg tcagctacag caacgccgac cgggacgcca
    12361 tcgcggattt cgccgaccgg ttgaccgctt cggcgccgca ctgaccgaac cgcgcggtcg
    12421 cgaaatccgt agcgactcag gccagagaca gcaacttggc ctggccggtg accacgatct
    12481 cgtcgcgatc gaccagtgcg acacgcacct gcaccgtctg ccccgccgcg accggtgtgc
    12541 cgaccaggcc gacaatcgca ttgtgggtac cgccatcgca ggtgacggcg gtctgtgtgc
    12601 cgtcggccga cggcgcatcg gcattggggt caccgaccat cgctcggatc gcgaccaccc
    12661 cggaggaggg ttcgcaactg tagtcgacgg cgatattggc cggaccgacc gcgccgatat
    12721 cgatactcgt cgcggcctga gcgggcgcgg cgaacccgag aacagccgag gccaacgcgc
    12781 ctaagacgcc gaacgcaagg acagggcggc tgacagacac catggatcct cctacctagc
    12841 gggagcacag ctggacacga tccagaaacg agcggtgcga ccgcaccgcg cctccatcgt
    12901 cgcgcaccac ggcggcccgt ggtcggaaac cgcccggact cgaggccgat cctgcgagaa
    12961 tcgggcgcgg gaccggcccc ggcaggcatt taggcgggcg ggacgagggt gatgaggaat
    13021 tcctcgtccc gcccgcccga acaccgtccc tgaaccacct cggcgcccgc cgccatatcc
    13081 tgatcgcgca gcgacaggca ctcgcgcgtc gcgtcgggac gcaatcggaa gtggccgact
    13141 gcgggcggcc ccaccgcttc gagccggaac cgctgggtcg gatcgcccga agcgcactcc
    13201 ccgcgcggtt cgagcagatc ccgacccggc ccgtcccgca acacggtgag acacccgaca
    13261 ccgaaactcg ggtggtgcca ctggattcgg accattcccc caccaaccgg ctcgagatag
    13321 acgcgcggca cccgagtctg cgcacagggc cgctgcaccg cgatcacgct gggatagtgg
    13381 cgagttcgat ccacaccgtc ggacaggcac agttcggggg tccgggccgg ttggatcaac
    13441 gcccaactgc cgatcgaggg cagagcgagt ccgggaacgg gatcgggcgt cccgctgtcg
    13501 gtcttgccgg atagcgcctg cacgcccaaa gtgcccagca cacccacgat tccggcgaac
    13561 aacagccaca ggaatctgaa cctgcgccgc accaatggct ccggctccgg ctcgactccg
    13621 tcctcacgct cccgcgaccg cgccgcgatc cgctcccgcg cgtccaacca ccgcgtcacc
    13681 tgctcgccgt cgagtccgca tgcgcgcacg aaacctgcca cgaaagattc gcgcggcagg
    13741 gtggcccgcc ccagcgtggt ggcgatcgtg ctggacggca gcacatctcc gttcgcggcg
    13801 gccttcccct gcaattgtcg ataggccagt ccggaccagc ttttcaacga ccgtagcgcg
    13861 gcgacatatt cggccgccgt ggcggcccgc tccggccgcg gactgtcctt cccgcgcgcc
    13921 ataccgtcca gcatgacaga aatttccacc tggcagcgtg ggatcgaatc ggaaattcag
    13981 cttgtccctt ctcatttcga ccggtgttcg aacggcaggt cgacctgttc cgaacacacc
    14041 cgaacgcgtt cgacccttgt ccgcgcccca ccccaccggc aaggctcgat atcgacgttg
    14101 cggccgggaa gcctgcgaaa caacggattc gagttagggg gtgcgccatg gactacccgc
    14161 actgagcgct gaactgatca gcaattgaga tcggggtgcc cggcgtcgcg agccgggcac
    14221 ccacagcttt ccttggacgg gagccgcatt tgtccacccc tcgcaccgcg aaaaccgccc
    14281 gcgcggaaat attccgaccg ctcgcgccgg aaatgctggc cgacccctat cccgtctacg
    14341 ccaggctgcg cgccgaggat ccggtgcact ggcacgaggg gctgcgcgcc ctggtgctca
    14401 cccggcacgc cgactgcaca cgggtgctgc gcgaacacgg cgtcttctcc gcggacccgc
    14461 gcaaactcgg caaacccatt gccgcccagg tgatcagcct gcaaacgatg gacccaccgg
    14521 agcattcgat catccgccac cacttcgtcg ccgcactcaa acgccgggat ctcgcgacct
    14581 gggccgcggg cgtcgccgcg accgccgacg aactcgtcgc cgccgtcggg accgagccct
    14641 tcgacttcgt cgccgatatc gccgaaccac tggcactttc ggccatgtgt ctgctctacg
    14701 gcgtgaacta tccgctcgac gacaccgtat tccgcaccgc gtcgcgcact ttggcgctcg
    14761 gtatggacgc gggcctggct cccgagcgcc gcgcccccgc tttggccgcg cgcgagacga
    14821 tcaacgagat gatccggcag tgggtatccg acccgccgcg ccactcggtc ctggcccatc
    14881 tcgacgacat cacggccgtc ccgtccgaac acctcgtcaa ttcggcccgc gcgatattcg
    14941 acgcgggcta ttcgaccacc gccaatttcc tcggcaacgc ggtacgctgg ttgctcgcca
    15001 atggccatcg ggatgcgttg ggcaccttgg acactcgcgc ggtggacgaa ctcgcgcgtc
    15061 tggtgggtcc ggtacaggcg gtcagcaggc tctgcctgga ggacaccgaa ttcggtggcc
    15121 ggagcatcgg ccggggcgag atcgtcatcg cgctgctggg tgcggccaat cacgatcccg
    15181 aggtcttccc cgatccgcaa cgcgccgaat tcggacgcgc acccaatccg catctgggtt
    15241 tcgggcgcgg ggtgcactcc tgtctcggta gccacatcgg caatcgaatc atggtggcgc
    15301 tcagccgatc cctcgcctcg gtgcgcctgg agagcgcggg cgcgcaccgt cagcggccca
    15361 ccgcgaccca gcgcggcctc gatctgctgc cgctgcgggt gcgatgatgc gcgcactact
    15421 gctcgcgctg ctgctcgcgg cgctgttcgc ccccgccgcc acggcgcaag acctggcggc
    15481 cgagaatatt tcgcgtgccg tcagcacctc cgacgccatg gccaccgtgg ccgcgctcga
    15541 cgccatcgcc gtcgccaatg gcggcaatcg ggagaccggc aaaccgggtt tcgcgcgctc
    15601 gcgcgaatat gtggagaacg cgctgcgacg cgcaggctac gacgtcgtcg cgcaaccggt
    15661 cccctaccgg gatttcgcgg ccgacaccga aactctcacc gcgcccgatg gccgccgaat
    15721 ccgcacgctc atggcgcaat tcgtcccctc cgggcaggtc accgggccgc tcgccgatgc
    15781 gggcgcgggc tgctctaccg cggactaccc gaagggcacc gccatcgccg tcatccgttc
    15841 cggcgactgc ccgtcgggcg ataagacggt agccgcgcgc gatgcgggcg tgcaggccgt
    15901 cctcgtctac gacgccggac cggcgatcga tgcggcgatc cggcgccaag tcccgcatgc
    15961 cgcactgcca gtcgggttcc tcagtcagcg cgacgcctcc gcgctcaccg ccgcgcccgg
    16021 ttcggcacag ctggaactgc gcggccacac cttcgacgac accgcggtca gcctgttcgc
    16081 ggaaacctcc ggcggacacc cggacagcgt cgtcatggcg ggtgcgcacc tggacagcgc
    16141 cgtggacgga cccggtatca acgacaatgg cagcagtgtc gccgcactgt tggagaccgc
    16201 gatccggctg gccccattcc aggatcgggt gccgaacaag gtgcgtttcg ccttctgggg
    16261 cgcggaggaa ttgatcgaca tcggctcgag ctactacatc gatacccgca cacccgccga
    16321 ggtcgccgcc atcgccctgt atctgaactg ggagatgatc ggctcgccga actacgcgca
    16381 tttcgtcatg gacggcgacg gcgcggacca tcccggcggg tcggcgggtc cgccgggttc
    16441 gggcaccgtc aaagccgtga tggcgcaggg ctatcagatc cagggggtgc cctaccgcac
    16501 ggcggacctc gcccagatcg gttcggatca ggagccgttc gcccgcgcgg gcatcccgat
    16561 cggcggcgcg ttcggcgggg tgcgcgcgct caagacgccc gaggaggcgg cggtcttcgg
    16621 cggcgtcgcc ggtcagccgt acgacccgtg ctatcaccag ccgtgcgaca acctcgccaa
    16681 cgtgaatccc aaggcattcg agcaggccct gcgcgcgatg gcatgggccg tcgcccgttt
    16741 cgccgtggac gaccacttaa agaagtaggc cccaccctcg ttgccgatat ggcaaagcaa
    16801 cgatgtccgt ttctgctgaa tagcgcactg cccggccact atcggttgcc aaatccgcaa
    16861 aaccacattg ccccgacgcg gaccacgacg caatgtcgta gaaccaccga cgaagggatg
    16921 ccgatgttct cgaaggtcat caccgatttc tggcgcgaac agatgttcgc ctccgcagcg
    16981 atcggcgcga acggcgactt cgcggtcacc gtcaatccgg acctgaagca ggacagcggg
    17041 gtcatgatcc tggagatcgc cgacggcgcg accatcgcca ccctcgcccc ggccctcgcg
    17101 gcgaagatcg gactgcaaag cgccgatgct ccgaccgcgg ccggattccg gaaactgctg
    17161 accgacgccg agatcgccct gaacggcgcc gacttcctgt tctatttcac cgaggcggcc
    17221 aagtccgaac tgctcgccga gaacaacgac agcagggtcc gcaggctcac cgccgaggat
    17281 gccgagctgt tcgcggcctt cgaatccgcc actcccgaac aggatctcga cgacgcctat
    17341 gtcgaactcg accacgagat cgtctacggc tcgttcgaca gtggcgcgct ggtctgcgcc
    17401 gccagctcct acacctgggc cgcgggcgac tacaccaggg agaaggactc cgcgatcagc
    17461 gacttcggcg tcgtcaccgt ccccgaacat cggggcaaag gccatgcccg cgcggcggtc
    17521 cgggcgctgg cccgccacgc ctacgccgcc ggactcgaac cccagtaccg ctgccaactc
    17581 gacaatgccg cctcggtggc cttggcgggc aagtcgggcc tgacgctgtt cggtaactgg
    17641 gaccggatcg ccgactgacc gaacgcactg tcgcacagcg atttccacag agggccgggg
    17701 cggcgttcat cgcctcggcc ctcgtcacca tcgcacatca ccgccattcc cgcggctaat
    17761 ccgccctagt cgagtacgac gaattccgcc gcccggattg tggtggcgca ccgaatcgcc
    17821 ggaacgcccg cgtacctaga ttgctcgaac acagacaatg cggtcgaacg gagttatcaa
    17881 tggcgacgca gcagacaatg gtggtcgcgg ccgatgcggc gcagcgccga cgaataacgc
    17941 gcacgggggc gatcaccgcg gtaatcctct tgctcgccta ttcgatcgac tatatcgatc
    18001 gattcggaat cagcatggcg ctgcccgcga tcggccgcga gttcggactg tccaagacct
    18061 cgcagggtct gctggtcacc gccttcgccc tggtgtacat gatctgccag attccggcgg
    18121 gcatggtggt cgatcggatc ggttcgcggg cgctgctgct cggcgcgctg atcatgtggt
    18181 cggtcttcac cctgatgacc gccgtgacaa cgactttcgc cctcttgctc gtggtgcgcg
    18241 gactcttcgg cgcgtcacag ggtttcttcc ccgcggcgag tttcaagacc atcgccgaac
    18301 gcaccacacc gcgcaatcgc ggcacggtca tgagcgtcgt gctcgccgcc gccggcgtcg
    18361 gcagctcgct gtccccgctg ctcatggggc cgctgctgga gcatttcggt tggcgcgggg
    18421 cattcctgtg gctggcgggt acgggcgcgc tcctcggcgt ggtgttgctc ctgctgctcc
    18481 ccaagccgct gtcgatcgaa ttgcgcgacg ccgagcgccc ggtgccgccg agcgccaagg
    18541 cccggcgcgc ggtcctgcgc tcgcctcggg tgtggctgct ggccggtgtg ttctgtgcgg
    18601 cgaatttcgt cacctacggg ttgatcacct gggtccccac ctatctgcaa ctggccaagg
    18661 gcatttcgat cggcaagacg ggcgtgctgg cctcgattcc catggcgacc agcgtattca
    18721 ccaccatcgc aggcggattc ctcttcgacc ggtatttccg ggacaatccg cgctggtacc
    18781 tgtgcgtcac actcggaatc ggcggcatat tcctgattcc catggcggcg gccgattccg
    18841 cgaacgcctt catcgtgtgg gagacctgtg cctccttcgt cgcgggtctg ggcagcggcg
    18901 cgctggtcgc cctgccgatg cggttgctgc cgtccacgct gaccggcacc ggaatgggcg
    18961 tcttcaattt cggcggccaa gtcgcgggcg tggccgcgcc gttgctgctc ggtatcgtca
    19021 tggacaagtt cagctatgcg gcggcgttcg gactactcgc ctgctcgtgt ctgatcgcgg
    19081 ccggactggc gctgtgcatt ccgcggcgcg tcgatccaac caatttcatc aagggagcac
    19141 tcagctgatg cacgacaaca acggtgcgac aacgcaatcg cggacgggag aggtgctgct
    19201 gcgcggcggc acggtatgcg atcccggatc gggtttctcg ggaacggccg atgtgctggt
    19261 gcgcgatggg aaagtcgccg ccctcggcgc cgatctcgcc gtcgcggcgg acatcccggt
    19321 gctcgatgtc agcgcgatga ttgtcggccc cggcttcatc gatctgcaca gccacgtcaa
    19381 ttccgttgcc gggcagcgat tgcaggcctt cgacggcgtc accaccgcac tcgaactcga
    19441 ggcgggcgca cccgatatcg aacagaccta ccgcgccgcc gcgcaggacg gtcgcccact
    19501 caactacggc tactccgcct cctgggccgc cgtgcgctac gccgcgcatc tgggcacgcc
    19561 gccccacgac ctgctcggcg tgctcggcgc gcccgaatgg cagcgcagct cctccgacct
    19621 ggaacgccgc acctggctcg acctgctcga aaaggagttg gccgcgggcg gactcggcgt
    19681 cggcatcctg ctcggttacg cgccgcgcac cgatcccgcc gaattcctgg ccgtggcccg
    19741 gctggcggcg caggcgggcg cgccgacctt cacccacgtg cgcgaattgg tcgagtccga
    19801 tccgaccacc ccgatcgacg gctccaccga aatcgccgtc gccgcggccg agaccggtgc
    19861 ggccatgcac cactgccacg tcaacagcac ctcccgccgc catatcgacc gggtgctgtc
    19921 cacgctggat acggcgcgtg cgagcggatc caaggtcacc gtcgaggcgt acccgtacgc
    19981 ggcgggctcc accgccatcg gcgcgttctt cctggcgccg gaacggcttt cccggtgggg
    20041 cgttgggccg agcgatatcg tgctggtcga caccggcgag cgcatcgccg atgccgcgcg
    20101 gctggccgcg gtccgggagg ccgatcccgg cgcgccgtgc atcatccact acctcgacga
    20161 gaccagcgcc gccgatatcg cgctgctgcg caactccctg gccttcgagg acagtatcgt
    20221 cgccagcgac gccatgttcg tcacctgggc cgacgggtcc cgcgaatccc tgcattggcc
    20281 gctgccgccc aacggtcgca cccatccgcg cacctcgggc acctacgcca aatccctgcg
    20341 cctgatggtc cgcgaatccg gcgcctggac ctggctggaa gcattccgcc gctgctccta
    20401 cctacccgcc agggtgctcg acaccatctg ccccaccatc cgccccaaag gccacctggg
    20461 catcggagcc gacgcggata tcgtcgtcat cgacccggca accgtcaccg accgcgccac
    20521 ctacgccgac cccacccgca cctcacaggg catccggcac ctgatggtca acggcacctt
    20581 cgtcattcgc gacaacaccc tgcgcaccga cgccttcccc ggccgtccgc tgcgcgcatc
    20641 gcccctcgcg tgaacaaaac cctcgcgtag gcgaacaggc ccgctccaga acccggagcg
    20701 ggcctgttcg cctcagcccg gattccccat ggcgagtagt ttgagttgca gcatggcgcc
    20761 gaaacgagaa tccgaatcgg tcaggtcgat accgcccacc tcggtgatgc ggcgcagccg
    20821 atagcgaaaa gtattggggt ggatataaac agcggcggcg gccgcgttca catccccgaa
    20881 cgcggtgagc caggcgtcga gagtcgcgac gagacaactg ccctgcgccg tgtcgtagtc
    20941 gcgcaggcgg gcgatcggac cggtcagcgg gtcgcggcgg atggtcatca gatcgtgcaa
    21001 ttcctggagc agggcctcgg
//
