LOCUS       NZ_QZFU01000023        22534 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Nocardia panacis strain YIM PH 21724 NODE_3, whole genome shotgun
            sequence.
ACCESSION   NZ_QZFU01000023
VERSION     NZ_QZFU01000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia panacis
  ORGANISM  Nocardia panacis
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 595801)
  AUTHORS   Miao,C.
  TITLE     YIM PH21274 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 595801)
  AUTHORS   Miao,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2018) Yunnan University, Yunnan Institute of
            Microbiology, 121, Kunming 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 29.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003598715.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 03:06:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,880
            CDSs (total)                      :: 6,804
            Genes (coding)                    :: 6,707
            CDSs (with protein)               :: 6,707
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 32 of 97
            Pseudo Genes (incomplete)         :: 82 of 97
            Pseudo Genes (internal stop)      :: 7 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:26:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 486327
            Orig. end                         :: 508861
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QZFU01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22534
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="2"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22534
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22534
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12534](-)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12534)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    complement(444..458)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.75"
                     /tool="antismash"
     gene            523..1959
                     /locus_tag="D5S18_RS21140"
                     /old_locus_tag="D5S18_21140"
     CDS             523..1959
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006898102.1"
                     /locus_tag="D5S18_RS21140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21140"
                     /product="amidase"
                     /protein_id="WP_120042758.1"
                     /transl_table=11
                     /translation="MKIDEYAALDATALAAVIAAGEVTADEVAAVATAAITEVNKELNA
                     VVAGPFDRPLDYAPDGRFAGVPFAIKDLVCQIAGVPTRLGTRLTGTGLVPPADSHLMER
                     FRAAGLATLAVTTTPELGFNGNSEALAYGSTRNPWHTAHSAGGSSGGSAALVAAGALPV
                     AHANDGGGSIRIPAACNGLVGLKPSRGRVPSGPGHSEGLFGCGVELAVSRTVRDTAALL
                     DEVAVSFPGDPFVIAQPARPWSQEVGADPGRLRIALHTESWAGSYVDPEVAQTVEAVAQ
                     VLEAAGHHVERATPRIEWQTVLNSTITLWTTFLAEAVAGLEAMTGTKASAENLERATLA
                     CVEHGRSLDALALCAALDAGNTITREVGRFFTEYDLLLTPVHNTPAPPLGHLDQNADLT
                     AVEWATHLFDNCSFTPLYNQTGMPAISLPLGQSTRGLPIGVQLGGPACSEALLLRVAAQ
                     LEQAMPWADRRPRVHAANFG"
     gene            2138..3532
                     /locus_tag="D5S18_RS21150"
                     /old_locus_tag="D5S18_21150"
     CDS             2138..3532
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018177619.1"
                     /locus_tag="D5S18_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21150"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_203236849.1"
                     /transl_table=11
                     /translation="MVTRTDTTIAAELIRILPAGRVITDPDVALGLSHDQAAWGPVGTP
                     AAVVRARDSAEVQQVVLACLKHGAPLVPRGAGTGLSGGANAIDGGVVLVLEAMDSILEV
                     DPLERIAVVQPGVVNDDLRSHVATQGLWYPPDPASSPWSTIGGNMATNAGGVCCVKYGV
                     TRDYVIAAEVVTGTGEIVRLGRRTAKGVAGYDLLGLMVGSEGTLGVITEITVKLRPLPP
                     AGVVVVGSFAKTVQAGAAVRAARAAGLQPAALELVDRHCLAAVDAWKNMGLSTEGEVLL
                     LARFDDAEAVTDAERMLECFRAAGATLADRSETAEEAEMLFAARRLAYPALERLGPVMT
                     EDVCVPIAAVTEMLARIDRIAQRHNVTIANIAHIGDGNLHPLLILAPGDEAKNARAHAA
                     FEEIMSEAIDLGGTITGEHGVGLLKQPGLHRELSPAVLEMHRAVKRALDPAGIFNPGKI
                     FDAARS"
     gene            complement(3972..4436)
                     /locus_tag="D5S18_RS21155"
                     /old_locus_tag="D5S18_21155"
     CDS             complement(3972..4436)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019930559.1"
                     /locus_tag="D5S18_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21155"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_239003906.1"
                     /transl_table=11
                     /translation="METTIEPSRAAKPQRHKVTGDVHLILRRGDAALFGQRQNTGYEDG
                     AWHLPSGHLEADESVVDALIREADEEIGVRIAAADVRFSHIMHNSSSGGRVAFFFTVDR
                     WDGEPTNREPDKCAALEFFPIGDLPDHMIEYCRAAMGHVADAEPFSVFGW"
     misc_feature    4421..4435
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.01"
                     /tool="antismash"
     misc_feature    complement(4678..4698)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.87"
                     /tool="antismash"
     gene            4751..5593
                     /locus_tag="D5S18_RS21160"
                     /old_locus_tag="D5S18_21160"
     CDS             4751..5593
                     /EC_number="3.2.2.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019930480.1"
                     /locus_tag="D5S18_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21160"
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="WP_120042762.1"
                     /transl_table=11
                     /translation="MLIELAIGDAYGAGFEYADRGFVVAHNDLTGYLQHPGHDTIRPGD
                     YTDDTQMTLAIAESIVSGEPWTPEHLADRFVAVFHRDPRDGYAGRFRDFLDTVHTGAEF
                     LERIIPASDKSGAAMRAAPVGLLPDIAEVLARTEIQARITHDTADGIESAQAAALAVHY
                     CRRHLGPTAEIRSWMGRQLGSRWATPWRGKVGSKGWMSVRAALTALSTGQSLTEILRTS
                     IAFTGDVDTVATIALAAASHSSDVRQNLPAALLSGLENGPFGRDYLYDLDQRLHAAVG"
     gene            complement(5665..6324)
                     /locus_tag="D5S18_RS21165"
                     /old_locus_tag="D5S18_21165"
     CDS             complement(5665..6324)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="D5S18_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21165"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_120042763.1"
                     /transl_table=11
                     /translation="MGDARTERWADNRVRMRRKLIDAAIQVIETEGPQASMRAIAAAAE
                     VSKPTLYRFFADKAELTLAISNRAKQDIAAGLAQVRTHPEGSPAAILNSALTGYAALIV
                     EHPHIARFLFQGTENPAARTLENWRAVRVEVADLITLLVGSPSATPEFDADFYASMVVG
                     AVKGAANWWHRTADHADSAEEFVRRMEPVVHAIVAGAAADAGVTIDFDKPLTITVP"
     gene            complement(6422..7570)
                     /locus_tag="D5S18_RS21170"
                     /old_locus_tag="D5S18_21170"
     CDS             complement(6422..7570)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012371.4"
                     /locus_tag="D5S18_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21170"
                     /product="serine hydrolase"
                     /protein_id="WP_120042764.1"
                     /transl_table=11
                     /translation="MRYPLLAATLVAALAVGGCGSQPEPDPLQRDVDAIVAVGTAGVQA
                     RVVDTVAGTNRTAVAGRADIAAPEPVSPDGYFRTGSLTKTLVATVVLMLVGEGRLTLDD
                     TVQRWLPDMVRGNGNDGTRLTIRQLLQHTGGIHDSPFEIATAEDYYRLRLQTRTPEETV
                     AAAMAHAPDFAPGSGWAYANVGYVLLGLIIEQVVHHPWHDEVRARILEPLGLRDTRWPG
                     DDPALPAPHAKGYQQFEVDGPMVEVTELVDADASGGYLSTTEDIGIFYRNLLGGKLLRP
                     DELKMMRTVVPVSGPTALAWPGAGYGLGLISVPLSCGGTYWMHNGGQTGYLTNAATTED
                     GSRSAVVAMSGTLAVGDDITHSKGFAQLHLANELIDHALCAK"
     misc_feature    complement(6734..6736)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(7556..7558)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7718..8086)
                     /locus_tag="D5S18_RS21175"
                     /old_locus_tag="D5S18_21175"
     CDS             complement(7718..8086)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020107081.1"
                     /locus_tag="D5S18_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21175"
                     /product="DUF427 domain-containing protein"
                     /protein_id="WP_120042765.1"
                     /transl_table=11
                     /translation="MTRTPRIPGPDHPITIEPTGGRVVVRSGDTVVADTTRALSLREAE
                     YPAAQYIPLEDVDQSLLVPSDTTTYCPFKGDASYCSLTTPEGELTDAIWSYREPYAAVA
                     PIAGHVAFYPDKVEIVIQ"
     gene            complement(8238..10004)
                     /locus_tag="D5S18_RS21180"
                     /old_locus_tag="D5S18_21180"
     CDS             complement(8238..10004)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="D5S18_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21180"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_120042766.1"
                     /transl_table=11
                     /translation="MSSRAKEDRMPRQLWQMLAGHRGALALGLLLMLVAAGLGIAQPLA
                     MKAVIDGLTASRSVVLLVIGLVVLMALEVVVNAAASYVLERTGERFLLRLRTRLFSRLL
                     RLTMPTFDRFRLGDLMSRASTDVIQVREAATRAAVELAASVVMIAATLVVMFLIDPVLM
                     CVVVGVLIAATAAISGLTAAIGRVSTKLQDTVGAMSADLERVMGAIRTVRASRAEQRET
                     QRLTELAHDAYTAGVRSAFLMAAVSSLINVAVNGAFVVVLLVGAVRVGQDALALSSLVA
                     LLLYANQLVLPVAQFVEGIATVYKVRGAAQRATEVFTLPVEESAPATVIDEPPRSAPVL
                     EIRNLRFGYTPDAPVLQDLSLTVPHNSLVALIGPSGAGKSTALGLINRFYQPWQGSIHL
                     DGYAATELDLAAWRARIGWVEQDCQILHGTLRDNLRYIAHDADDRALWHAIDLVNLREK
                     VEKLPDGLDSQVGEHGARLSSGERQRVAIARAVLARPRLLLLDEPTAHLDPANEAALTT
                     TLDNLRGECALLVIAHRMSTIRSASSILLLANGTARATGTWTELFESPAEFGRLVNMRE
                     PEFSTAPSLREI"
     gene            complement(10001..10720)
                     /locus_tag="D5S18_RS21185"
                     /old_locus_tag="D5S18_21185"
     CDS             complement(10001..10720)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033537.1"
                     /locus_tag="D5S18_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21185"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_120042767.1"
                     /sec_met_domain="PF13471 (E-value: 3.1e-25, bitscore: 83.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.3e-18,
                     bitscore: 60.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.6e-13, bitscore: 44.8,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPCAPPERIRLPWRQRVLPLIAVAVAAPLTILPPKNLRWVLEF
                     ARRGARPAPADQTSRARQAIMAVSLRCAVNGCLQRSIATALLCRVRGVWPTWRLGVCTA
                     PFGAHAWVEAEGRMIDEPMPAGHYTPMLTVAPAQVAADPDHYSEMGTGTGDFRLHRQVL
                     SVGTSDGAVLLHLRTGHYWQLNPVGLDSLRHLLSGRSVEDIATDFAAEYAIDPAGPRRD
                     ITVMTDQLREAGFLVGP"
     aSDomain        complement(10013..10252)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_D5S18_RS21185_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="2.70E-19"
                     /identifier="RREFam002.1"
                     /label="D5S18_RS21185"
                     /locus_tag="D5S18_RS21185"
                     /protein_end="236"
                     /protein_start="156"
                     /score="60.0"
                     /tool="antismash"
                     /translation="RLHRQVLSVGTSDGAVLLHLRTGHYWQLNPVGLDSLRHLLSGRSV
                     EDIATDFAAEYAIDPAGPRRDITVMTDQLREAGFL"
     gene            complement(10717..12534)
                     /locus_tag="D5S18_RS21190"
                     /old_locus_tag="D5S18_21190"
     CDS             complement(10717..12534)
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="D5S18_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21190"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_158607916.1"
                     /sec_met_domain="Asn_synthase (E-value: 1.1e-33, bitscore:
                     112.4, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYALTNSLVVLPDSPGGVLAGRRVPHHDPKIIDHSSGRPWLIGHW
                     AAENLVVADAGGVRVAVFGECPIGPEQLTAAAAGIRTPSDLDALARTLPGSAHLIASVH
                     GRVRFQGTLTGTRQVCTARLDGITIASDRADTLAVMIDAEPDEDMLAVNIACQQLIPPL
                     SERTWWRGVRRIAPDSYLLLDGEDRARPVRWWTPPEPDLSIAEGSGQVRAALREAVAWR
                     RPTRGRLSADLSGGMDSTSLCFLAAEHTPNLLIFRRTGSSAINDDPFYAGEAAKLLDRA
                     DYIHLQSEDGPKVFEPPYILPDTEAPHALTRGVNTMDHQIQELVRRGATLHLAGHGGDE
                     LFSGGAGYLHTLLRRNPLRALRDLRVRRALGRWPLGSTMVALATGASLSSWWRHTADHL
                     TDPPPPPNAPQLGWAYPLRITPWATADAVHTARRVLRDIADEAVPLADDRGQHEALTYL
                     RFAGPLFRQLCRTYANGGLRLDLPYLDDRVIEAALAVRCEERFNPWHYKPLLAAAMRGQ
                     VPDLILDRRTKGEYDSEVENALNQHVPDLLELFADSALATRGLIDVDALRRYLYTPVGG
                     ADDDPAPNLEMTMGCELWLRQVATVRVKL"
     gene            complement(12668..12805)
                     /locus_tag="D5S18_RS34950"
     CDS             complement(12668..12805)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS34950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158607917.1"
                     /transl_table=11
                     /translation="MQNTSRTGAKRYVPPVAAKVGRVATDTFGTIHTKKDATTFGFKKG
                     "
     CDS_motif       complement(12722..12805)
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MQNTSRTGAKRYVPPVAAKVGRVATDTF"
                     /locus_tag="D5S18_RS34950_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       complement(12668..12721)
                     /prepeptide="core"
                     /locus_tag="D5S18_RS34950_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-7.40"
                     /molecular_weight="1819.1"
                     /monoisotopic_mass="1818.0"
                     /core_sequence="GTIHTKKDATTFGFKKG"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MQNTSRTGAKRYVPPVAAKVGRVATDTF"
                     /leader_location="[12721:12805](-)"
     gene            complement(13283..13420)
                     /locus_tag="D5S18_RS34955"
     CDS             complement(13283..13420)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS34955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158607918.1"
                     /transl_table=11
                     /translation="MQNTSRTGAKRYVPPVAAKVGRVATDTFGTIHTQKDATTWGFKKG
                     "
     misc_feature    13670..13685
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.03"
                     /tool="antismash"
     gene            complement(13984..14808)
                     /locus_tag="D5S18_RS21200"
                     /old_locus_tag="D5S18_21200"
     CDS             complement(13984..14808)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_21200"
                     /product="hypothetical protein"
                     /protein_id="WP_120042770.1"
                     /transl_table=11
                     /translation="MSQILGGRTPFDDIYDQPDPRGYFGSLGRFDYRTPHHAQAVFRRL
                     VAARAQSGPVTVVDLCCSYGINAALLNHDLTLADLYARYTLPQIAELDTVELIESDKEF
                     YAARRRDDAVPVVGVDIAAPAIDYALAVGLLDAGFVENLETGAASPALLRAAGPAGLIT
                     VTGGASFLTARTFQQLLGAAVEPVWVAAFVLRTGSYRPIADALAEYGLVTEVDPARTVL
                     QRRFTDLDEQRYAIAAVTEAGADPAGKETEGYYHAAVHLSLPPGVTGHPSAR"
     gene            complement(14877..15986)
                     /locus_tag="D5S18_RS21205"
                     /old_locus_tag="D5S18_21205"
     CDS             complement(14877..15986)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019927588.1"
                     /locus_tag="D5S18_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21205"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_120042771.1"
                     /transl_table=11
                     /translation="MIIAIVGAGMGGLALARVLHLHGIEAVVYERESSRAARGQGGMLD
                     IHSGQRALREAGLIDRFHAIARSEGQDMRLLEPDGTLLLRQDTPEDAPLDRPEVDRADL
                     RDMLLDSLPADAVRWGHAFNSADNGLLRFADGSSATYDLLVGADGAQSRVRALLTDARP
                     AHLGQNVVEVGIPDIDRTHPELAAMVGRGNFWVIGNGLSLAAQRNGDGRVRIGVCFYNT
                     PENWFATSAIPFDDPAAVRARLIELLPGWDARFTALIAACDDLVAPRSISALPVGLIWP
                     SQPDRTLVGDAAHLMPPVGEGANMALLDGASLGLALAAHQGDIPTAVATYEREMFERTG
                     AAARMSARVQELLTAPDASRRMLAFFQPD"
     misc_feature    complement(15981..15996)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.68"
                     /tool="antismash"
     gene            16055..16735
                     /locus_tag="D5S18_RS21210"
                     /old_locus_tag="D5S18_21210"
     CDS             16055..16735
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019927589.1"
                     /locus_tag="D5S18_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21210"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_120042921.1"
                     /transl_table=11
                     /translation="MLVWERPEPQDRPVPAPLSRERIVGAAIRLADEDGLAAVSLRKVA
                     AALNVGPMRLYGYIATKEELLDLMVDAVHAEIRPIGDGWREVLRSLAETTRQAAHQHEW
                     FADLLGGRPQLGPHALAGGEAVVAAMGGVDVDTVMPVVAAVNAYVIGAVRGEITERRAE
                     RTTGMDTRQWQAAFGPYLERTFATGRYPALATVIRDGAHLDADQTFDVGLELLLDGIQS
                     RISS"
     gene            complement(16747..17496)
                     /locus_tag="D5S18_RS21215"
                     /old_locus_tag="D5S18_21215"
     CDS             complement(16747..17496)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080174.1"
                     /locus_tag="D5S18_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21215"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_162500985.1"
                     /transl_table=11
                     /translation="MTDSELWGRASAERYDAEETVMSSAAVLAPTLDFLAELAGDGRAL
                     EFAIGTGRVGIPLRGRGVPVAGIELSEHMVAVLRRKIDQDTLPVTIGDMATTVVPGEFA
                     LVYLVYNTISNLLTQDAQVRCFRNAARHLRPGGRFVIELEVPPLRLLPPGQVAVPFDVS
                     ARHLGFDTIDVVEQLLVSHHFTRDGDHYRRDTSRHRYAWPAELDLMARIAGLEPEHRYA
                     DWAGTPFAADSTKHISVWRKPVRGRPL"
     gene            17670..17882
                     /locus_tag="D5S18_RS21220"
                     /old_locus_tag="D5S18_21220"
     CDS             17670..17882
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_21220"
                     /product="hypothetical protein"
                     /protein_id="WP_120042773.1"
                     /transl_table=11
                     /translation="MTEHAANETIVPATTRDLHEVVENYIRLRAITSPGNQGSIGFHRS
                     LGFEANLVADYNGPGMARIVFSRDL"
     misc_feature    complement(17976..17991)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            17976..18344
                     /locus_tag="D5S18_RS21225"
                     /old_locus_tag="D5S18_21225"
     CDS             17976..18344
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005253165.1"
                     /locus_tag="D5S18_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21225"
                     /product="hypothetical protein"
                     /protein_id="WP_239003907.1"
                     /transl_table=11
                     /translation="MKTTTIAATRVAAAAASVLGFAAVIGTGTAQASAQDCTVTRDLFG
                     ATAACRDTEAPAGREYTLVVECVGLHGIPNAFPLMTIGPYQGSWGGSFGPSGQGTASCL
                     GPTSVGTVTNAYVAVYRD"
     gene            complement(18529..19092)
                     /locus_tag="D5S18_RS21230"
                     /old_locus_tag="D5S18_21230"
     CDS             complement(18529..19092)
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="D5S18_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21230"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_120042774.1"
                     /transl_table=11
                     /translation="MDGIAIRTATENDERALAAIDHATWSRQVHPIPLWPSDTPFFDEG
                     TAPRNVLLAHEDNHILGYVKLRPAPMRASSGHVQEINGLAVAPHHQRRGIGHLLLDAAR
                     AAAVERLARRITLRVLGTNVRAQKLYLAHGFRIEGTLVGQFLIEDRYVDDVLMALEICP
                     ATHRRDRATTVHPGIPASDRRDTL"
     misc_feature    complement(19126..19137)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.96"
                     /tool="antismash"
     gene            19217..19504
                     /locus_tag="D5S18_RS21235"
                     /old_locus_tag="D5S18_21235"
     CDS             19217..19504
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_21235"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_147404044.1"
                     /transl_table=11
                     /translation="MRTTDSVASADGTRIVFHTLGDGPPLVIVHGALVTTEAYRPMAEL
                     LATSYRVVLIGRRDYAPSGNGPRPSTFIDAPFPTAPCAPWEQPWPTARRD"
     gene            19480..19737
                     /locus_tag="D5S18_RS21240"
                     /old_locus_tag="D5S18_21240"
     CDS             19480..19737
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_21240"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_120042776.1"
                     /transl_table=11
                     /translation="MADRAPGLIADLECLTAMDPDPNRWSATTAPGLLLAGSSSDRYGL
                     ESMAKLEAALPNSQFTVLEGLTHNPDDFTPIATAMSEFFR"
     gene            complement(20021..20929)
                     /locus_tag="D5S18_RS21245"
                     /old_locus_tag="D5S18_21245"
     CDS             complement(20021..20929)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF014566.4"
                     /locus_tag="D5S18_RS21245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21245"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_120042777.1"
                     /sec_met_domain="Abi (E-value: 1.1e-15, bitscore: 53.0,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNGNAVLSPRAGDSRRRSGRELVIFLVAAYLGAWLVAAPLWVTG
                     FRRVAPGQEATTLATVCLFTMMVVPATVAVVLTRWRHPWRAVPQVLSLGLPGPRVLAQC
                     VGAGVIFPAIAAVGLLPAAAIGVFRPGWPQSWAPLLTMLVSALISLPLYLGEEIGWQGY
                     MLPRLTFRYGPVLGIGVGGVLWGLWHLPMTALGGSYPGHPLYVAIPMAVGAAVGIGAVI
                     AAIRIHTRSVWPAVAAHAGLNEFALRLPRFFAARDHIPDPLIVGPLGLITWPILMVAAG
                     FALYSLRTRRPGLSSGAAHSK"
     misc_feature    complement(20048..20050)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(20573..20575)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21040..22266
                     /locus_tag="D5S18_RS21250"
                     /old_locus_tag="D5S18_21250"
     CDS             21040..22266
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025168.4"
                     /locus_tag="D5S18_RS21250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_21250"
                     /product="histidine kinase"
                     /protein_id="WP_203236836.1"
                     /transl_table=11
                     /translation="MSFAMWWVRWRGALVDGVRTLALGLYAILALPLLVYTAVTCLVGI
                     GFVLVPPQLWVLGRVADAERRRIARRRGTIAETVDRPFRWLPALVTDPTVWRELRWVAF
                     LAVGGTVLGALGTGVAVLPLLAFAAIWLWWLFPADDPIRIVANIPIAGWPSALTIGVAQ
                     CAITAAVAVAAGPALGRAGLWLSNAGLRVSAKKRLTQQVAALRRTRSGAVDAHTADLRR
                     IERDLHDGTQAHLVALALRLGLASRALDRDPSAVGPLLEEARAGAEAAMSDLRTVLRTT
                     YPPILADQGLDGAVAAVAARCTVPTAVRVELDRELPAAVEAAVYFVVTEALTNIARHAG
                     ATSAAVEVRTTADGVAVEIRDNGRGGVDPARGTGVAGMLRRLEALDGVLTVDSPPGGPT
                     VLRAVCPCG"
ORIGIN
        1 gagcggtagc gtgagtccct cacgaaaacc attgggctgt agtgcgtccc gataggttcg
       61 ggtttcgcgg acatcgaagg gcacgtcgat gaatcgcagg gcgatgccgt cgcgcaccgc
      121 gatccgatgc accgggcagg atcgactgta ggtcgtggtc aggtaggcga gggtcgcgtc
      181 cgggtagtcg aggttgacca gcgcggtccg cgcctcgccg ccgaacccgc gcgcgaccag
      241 tgcggcgcag tcgtatccga gtctgtcgcg cagggcacgc accggatccg cgatgggtat
      301 ctcgccgcgg cccgccgcac ggatctcccc ggcgagccgg gtccaccact gtatttccgc
      361 gaccattgcg aacctccaat gtcagacagc attgcggcgg tccgatgcca cgtcaagctt
      421 ccgccgcata tccgggcggc gaccggaacg gcttttcggc cgatgtgcgc tacctcacgg
      481 ctgggtagcg tcgcgccgaa cactcgcagt aaggaagtca cgatgaagat cgacgaatac
      541 gccgcactcg acgcgaccgc gctggccgcg gtcatcgccg ccggggaggt caccgccgac
      601 gaggtggccg cagtcgccac cgcggcgatc accgaggtga acaaggaact gaacgcggtc
      661 gtcgccggac cgttcgaccg tcccctcgac tatgcccccg atggccgatt cgcgggcgtg
      721 cccttcgcga tcaaggatct ggtctgtcag atcgcaggcg tgccgacccg cctgggaaca
      781 cgcctcaccg gcaccgggct cgtcccgccc gcggattcgc atctgatgga acgcttccgc
      841 gcggccggtc tggcgacact ggccgtgacg acgacaccgg agctgggttt caacggcaac
      901 tccgaggccc tggcctacgg ttccacgcgc aacccatggc atacggccca cagcgcgggc
      961 ggttcgagcg gcggctcggc ggcgctcgtc gcggccggtg cgctgccggt cgcgcatgcc
     1021 aatgacggtg gcgggtccat ccgtattccg gccgcctgca acgggctcgt cgggctcaag
     1081 ccgagtcgcg ggcgggtgcc ctcgggaccg ggccattccg agggcctgtt cggatgcggt
     1141 gtcgaactcg cggtgagccg gacggtgcgc gacacggcgg cgctgctgga cgaggtggcc
     1201 gtgagctttc cgggcgatcc cttcgtcatc gcccagcccg cgcgcccctg gagccaggag
     1261 gtgggcgccg atccgggcag gttgcgcatc gccttgcaca ccgaatcctg ggcgggaagc
     1321 tacgtggatc ccgaggtcgc ccaaacggtc gaggccgtcg cgcaggtgct ggaagccgca
     1381 gggcatcacg tcgagcgagc gacgccgcga atcgaatggc agacggtgct gaactcgacc
     1441 atcaccctgt ggaccacctt cttggccgag gcggtcgcgg gactcgaggc catgaccgga
     1501 acgaaagcga gcgccgagaa tctcgaacgc gccacgctgg catgcgtcga acacgggcgc
     1561 tcactcgacg ccttggccct gtgcgcggcc ctcgacgcgg gcaacaccat cacccgcgaa
     1621 gtcggacgat tcttcaccga atacgacctg ctgttgacac ccgtgcacaa cacgcccgcc
     1681 ccaccgctgg gccacctcga ccagaacgcg gacctgaccg ctgtcgaatg ggccacgcac
     1741 ctgttcgaca actgctcgtt cacgccgctg tacaaccaga ccggcatgcc cgcgatcagc
     1801 ctcccgctcg gccagtccac gcgggggctg cccatcggcg ttcaactcgg cgggcctgcc
     1861 tgttcggagg cgttgctgct gcgggtcgcc gcccagctcg agcaggcgat gccgtgggcg
     1921 gatcggcggc cgagggtgca cgcggcgaac ttcgggtagc gatgtgtacc gccgaatggt
     1981 cggcggtaca tcccgacaag cccaacccgt cggatgcgcg aatcacgcct catggcagcg
     2041 tatcgcgtga ctcgccgatc gatggcgcgg tcgtgaaccg gtatcgaccg gtgcgacttc
     2101 ggatcgacga gccgagcagc aacgaacttc agaggacatc gtgacccgca cagacaccac
     2161 catcgccgcc gaactcatcc ggatcctccc cgcgggccgg gtaatcacgg acccggatgt
     2221 ggcgctgggc ttgtcacacg atcaggccgc gtggggtccg gtcggcacac ccgccgccgt
     2281 cgtgcgggca cgcgacagcg ccgaggtcca gcaagtggtg ctggcctgct tgaagcacgg
     2341 cgcgccgctg gtcccgcgcg gcgcgggaac agggctgtcc ggcggggcca atgccatcga
     2401 cggcggcgtg gtcctcgtct tggaggcgat ggactcgatt ctggaagtcg atccgctcga
     2461 acgcatcgcc gtcgtacagc cgggcgtcgt caacgacgat ctgcgctcgc atgttgcgac
     2521 gcaaggtctc tggtacccac ccgaccccgc cagctcgccg tggtcgacga tcggcgggaa
     2581 tatggcgacg aacgcgggcg gcgtctgctg cgtgaagtac ggcgtcactc gcgattacgt
     2641 catcgcggcc gaggtggtga cgggcaccgg agagatcgtg cgattgggtc gccgcaccgc
     2701 caaaggggtc gccggatacg acctgctcgg tctcatggtc ggctccgaag gcaccctcgg
     2761 ggtcatcacg gagatcaccg tcaaactgcg cccactgccg cctgccgggg tcgtggtggt
     2821 cggatccttc gcgaaaacgg tccaggccgg tgccgcggtc cgcgccgccc gcgccgccgg
     2881 attgcagccc gccgcactgg aactggtcga ccgacactgc ctcgcggcgg tcgacgcgtg
     2941 gaagaacatg ggcctgtcca ccgagggcga ggtcctactg ctggcccgct tcgatgacgc
     3001 cgaggccgtc accgacgcgg aacggatgct cgaatgcttc cgagctgcgg gcgctaccct
     3061 cgccgaccgg tcggaaacgg ccgaggaagc cgaaatgctg ttcgcggcac gccgactcgc
     3121 ctatccggcc ctcgaacgac tcggaccggt catgacggaa gatgtctgcg tcccgatcgc
     3181 ggcggtaacg gaaatgctgg cccgcattga ccgaatcgcc cagcgacaca atgtcaccat
     3241 cgccaatatc gcccacatcg gcgacggaaa cctgcaccca ctactgattc tcgcccccgg
     3301 cgacgaagcc aagaatgcgc gagcacacgc ggcattcgag gagatcatgt ccgaagccat
     3361 cgacctcggc ggcaccatca ccggcgagca cggcgtcggg ttgctcaaac agcccggcct
     3421 ccaccgcgaa ctcagcccgg ctgtcctgga gatgcatcgc gccgtcaaac gggcactgga
     3481 tcctgcggga attttcaatc cggggaagat cttcgacgcc gcgcgttctt gagttcccgg
     3541 catcgtttgc tgccgactgc taccggaatg gcacaggccg caggcccgac catggtcgcg
     3601 gaccgagtct tcctcggaga caagctattc ggtgggcagc ctgtgcgccg tcggcttcga
     3661 tcgtcaccgc ggtttgtgta gccatggtcg tcatcccgtg atggcaagcc gcgctggaat
     3721 acaatggtca gcctgatctc cagaggatca agcttggact cggcgacgac gtgccgacct
     3781 acggcagcca ctggcgggcg ctggtggcgt acatcaaact ccaactctcg gagccgggcc
     3841 tgaagattcc ttggaatgat gacccgccgc catcgcgcga gcgtcctgag tcgaaggctc
     3901 ggcagaacaa tcacccggac cgctccggta ggttctggcg cgcccgggct cactgtccca
     3961 tggtcatgct gctaccagcc gaataccgag aagggctcgg catcggccac gtgccccatc
     4021 gccgcacgac agtactcaat catgtggtcc ggcaggtcgc cgatcggaaa gaactccagt
     4081 gcagcgcatt tgtccggttc acggttggtc ggttcaccat cccatcggtc caccgtgaag
     4141 aagaacgcca cccgaccacc ggacgacgag ttgtgcatga tgtggctgaa acggacatcc
     4201 gcagccgcga tacgcacgcc gatctcctca tcagcctccc gaatcagtgc gtccacaacc
     4261 gactcatcgg cttcgagatg accggaaggc aaatgccacg caccatcctc gtacccggtg
     4321 ttctggcgtt gcccgaacag cgccgcatcg ccacgacgca ggatcaggtg cacgtcaccg
     4381 gtgaccttgt gtcgctgcgg ctttgccgcc cgacttggct cgattgtcgt ttccaagata
     4441 tctccctccg ggacgaaacg tatgtgttga cctggacagt tggagcaacc gtcggtcgag
     4501 cgattcgagc gtaatccgtt caacgcgagc aggttatgcg ccgagtacat aggagggatc
     4561 gcgtcgaacc gtctgttcag acgtcactct gcctgctcgc tgccgaatca gcctcgaccg
     4621 cgctgcgcag gctgggtatc tctgtcgatc cgagtcgatc gaatcacacc gcaccagttc
     4681 tagtcgtatc gaccaattta ctgctacgct gcgtccgcac cgggagttca ccacaggaag
     4741 gggagggcgc atgctgatcg agttggcgat cggagacgcg tacggagccg gattcgagta
     4801 cgcggaccgg ggattcgtcg tcgcacacaa tgatctgacc ggctaccttc agcatccggg
     4861 gcacgacacg attcgtcccg gcgactacac cgacgacacc caaatgacct tggcgatagc
     4921 ggaatcgatc gtttcgggcg aaccgtggac gcccgagcac ctcgccgacc gtttcgtcgc
     4981 ggtcttccac cgcgatccgc gcgacgggta cgcgggccga ttccgcgact tcctcgacac
     5041 ggtccacacc ggagccgaat tcctcgaacg catcatcccc gccagcgaca agagcggtgc
     5101 ggcgatgcgc gccgccccgg tcggtctact gcccgatatc gccgaggtat tggcccgcac
     5161 cgagattcaa gcccgcatca cccacgacac cgccgacggc atcgaatccg cccaggccgc
     5221 ggccctcgcc gtgcactact gcaggcgcca cctcggcccg accgccgaaa tccgttcctg
     5281 gatgggccga caattgggat cgcgctgggc caccccatgg cgcgggaagg tcgggtccaa
     5341 agggtggatg agcgtccgcg ccgccctcac cgccctgtcg accggccaat ccctcaccga
     5401 aatcctgcgg accagcatcg ctttcaccgg cgacgtggac accgtcgcca ccatcgccct
     5461 cgccgcggcc tcgcattcct cggatgttcg ccaaaacctt cccgccgcac tgctttccgg
     5521 cctggagaac ggccccttcg gccgcgacta cctctacgac ctcgaccagc gcctccacgc
     5581 ggcggtcggc tgacggcacg actcgacggg gagtgcgctg ccgacaccga tgtggcgttg
     5641 tccaggccac agggtcgaga agcgttaggg gacagtgatt gtgagcggtt tgtcgaagtc
     5701 gatggtcacg cccgcatcgg cagccgcgcc cgcgactatc gcgtggacga ccggttccat
     5761 gcggcgcacg aactcctcgg ccgagtccgc gtggtcggcg gtgcgatgcc accagttcgc
     5821 cgcgcccttc accgctccga caaccatcga tgcgtagaag tcggcatcga attccggggt
     5881 ggcgctcggt gatccgacga gaagggtgat caggtcggcg acttcgacgc ggacggcccg
     5941 ccagttctcg agtgtcctgg cggcgggatt ctccgtgccc tggaacagga atcgcgcgat
     6001 atgcggatgt tccacgatca gcgcggcgta tccggtgagt gcggagttca ggatcgccgc
     6061 cgggctcccc tcgggatgcg tgcgcacctg cgccagtcct gccgcgatat cctgcttggc
     6121 ccggttcgag atcgcgagcg tcaattccgc tttgtcggcg aagaatcggt agagggtggg
     6181 tttggagacc tccgccgccg cggcgatggc gcgcatactg gcctgcggtc cctcggtctc
     6241 gatgacctgg atggcggcat cgatcagctt gcggcgcatc cgcacccgat tgtcggccca
     6301 ccgctcggtc cgggcgtcgc ccacggttca cctttccgac ggtcttcgcc gatcggcgcg
     6361 aataccgcct tgtatcagcg attttagcag ggtgggccgc tgcgtcggcg gtcatggcgc
     6421 actacttcgc gcagagtgcg tggtcgatca attcgttggc caggtgcagt tgcgcgaatc
     6481 ccttgctgtg ggtgatgtcg tcgccgacgg cgagtgtccc ggacatggcg acgacggcgc
     6541 tgcggctgcc gtcctcggtg gtggcggcat tggtgaggta tccggtctgg ccgccgttgt
     6601 gcatccaata ggtcccgccg caggagagcg ggaccgagat cagaccgagt ccgtagcccg
     6661 cgccgggcca ggccagtgcg gtcgggccgg agacgggaac cacggtgcgc atcatcttca
     6721 gttcatcggg ccgtaatagt ttgccgccca agagatttcg gtagaaaatc ccgatatcct
     6781 cggtagtgga cagatatccg cccgaggcat cggcgtcgac caattcggtg acctccacca
     6841 tcggcccgtc cacctcgaat tgctgatagc ccttcgcgtg cggcgcgggc agcgcgggat
     6901 catcgccggg ccagcgggtg tcgcgcaggc cgaggggttc gaggattcga gcgcgaacct
     6961 cgtcgtgcca gggatggtgg actacctgct cgatgatcag acccagtagg acgtagccga
     7021 cgttggcgta ggcccagccg gagcccggtg cgaagtccgg agcgtgcgcc atggccgccg
     7081 caacggtctc ctcgggagtg cgggtctgca atcgcaaccg gtaatagtcc tcggcggtgg
     7141 cgatttcgaa cgggctatcg tgaattccgc cggtgtgctg aagaagctgc cggatggtga
     7201 ggcgagtgcc gtcattgcca ttgccgcgca ccatatccgg cagccaccgc tgcaccgtgt
     7261 cgtcgagggt gagtctgccc tcgccgacca gcatcaggac cacggtcgcg accagcgtct
     7321 ttgtcaggct gccggtgcgg aagtagccgt ccggcgaaac cggttcgggc gcggctatat
     7381 ccgcgcgtcc cgccactgcc gtccggttgg tcccggccac ggtgtccacc actctggcct
     7441 gtacgcccgc ggtgcccacc gcgacgatcg cgtcgacatc gcgttgcagt gggtcgggtt
     7501 cgggttggct gccacatcca ccgaccgcca aggccgcgac cagtgtcgcg gccagtaacg
     7561 ggtatcgcat cgcttctcct ctcggatccg cgacaatcct tcagtcccgc acccgcgccg
     7621 acatcccgct gtggtagcgg tccggcacat actgcggtac gggaagaaca tgtcgcaccg
     7681 tacccgggtg tcggtgcgat catcggtcac gtgaaaccta ttgaatgacg atctcgacct
     7741 tgtccgggta gaaggcgaca tgccccgcga tgggggcgac ggccgcatag ggttcgcggt
     7801 aggaccagat cgcgtcggtc agctcacctt cgggagtggt gaggctgcaa taggacgcgt
     7861 cacctttgaa agggcagtag gtggtggtgt ccgaggggac caacaggctc tggtccacat
     7921 cctcgagcgg aatgtattgt gcggccggat attcggcctc gcgcagggac agcgccctgg
     7981 tggtgtcggc gaccacggta tcgccgctgc gaacgacgac gcggccgccg gtgggctcga
     8041 tcgtgatcgg gtggtccggt ccgggaatcc tgggtgtacg cgtcatggct gcgtctcttt
     8101 cgcatagcgg cggtcgtatt gttcggcgtt ctatccgagg ctactgcgga tgacccactg
     8161 ccccgtatac agggaggtgg accgggaaga agtcaagcgg ctatcggccc agccgctgtg
     8221 cgcgcctccg gtcgggatca gatttctcgc agcgatggag cggtgctgaa ttcgggttcg
     8281 cgcatattga cgagtcgacc gaactcggcg ggggattcga atagttccgt ccaggttccg
     8341 gtggcgcggg cggtgccgtt ggccaacaag agaatggagg aggcggagcg aatggtcgac
     8401 atgcggtgcg cgatcaccaa aagggcgcat tcgccgcgca ggttgtcgag cgtggtggtc
     8461 agcgccgctt cgttggccgg gtccaggtgg gcggtcggct cgtccaggag cagcaggcgg
     8521 gggcgggcga ggacggctcg ggcgatggcg acgcgctggc gttcgccgct ggacaatcgc
     8581 gcgccgtgtt cgccgacttg actgtccaaa ccgtcgggca gcttctcgac cttctcccgc
     8641 agattgacca gatcgatggc gtgccagagg gcgcggtcgt cggcgtcgtg ggcgatgtag
     8701 cggaggttgt cgcgcagtgt gccgtgcagt atctggcaat cctgttcgac ccagccgatg
     8761 cgggcgcgcc aagcggcgag gtcgagttcg gtggccgcat atccgtcgag atgaatgctg
     8821 ccctgccacg gttggtagaa ccggttgatc agcccgaggg cggtggattt gcccgcaccc
     8881 gacggcccga tcagggcgac cagcgagttg tgcggcacgg tgagggaaag gtcttgcagc
     8941 acaggcgcgt ccggtgtgta gccgaagcgc agattccgga tctccaacac aggggcggat
     9001 cgcggcggct catcgatgac ggtggcgggc gcggattcct cgacgggcag cgtgaacacc
     9061 tcggtggcgc gctgagccgc gccccgaacc ttgtagaccg tcgcgatgcc ctccacgaac
     9121 tgggctacgg gcagcacgag ctggttggcg taaagcagca gcgccaccag tgaactcaag
     9181 gcgagcgcgt cctgcccgac ccgcaccgcg ccgaccagca gcacgacgac gaaggccccg
     9241 ttgacggcca cattgatcag cgagctcacg gccgccatca ggaacgcgct gcgcaccccg
     9301 gcggtgtagg cgtcgtgcgc gagctcggtc aggcgctgtg tttcgcgctg ttcggcgcga
     9361 ctggcccgca ccgtgcgaat cgcccccatc acgcgttcca ggtcggccga catcgcaccc
     9421 acggtgtcct ggagtttggt ggagacccga ccgatcgcgg cggtcaggcc gctgatcgcg
     9481 gcggtggccg cgatcagcac cccgacgacg acgcacatca gcaccgggtc gatcaggaac
     9541 atcaccacca gggtggccgc gatcatgacc acgctcgccg cgagctccac cgccgccctg
     9601 gtggcggcct cccgcacctg gatcacatcc gtcgatgccc tggacatcaa gtcgcccaac
     9661 cggaatcgat cgaaggtggg catcgtcaac cgcagcagtc ggctgaacag ccgggtccgc
     9721 agccgcagca ggaatcgttc gccggtgcgt tccaacacat acgaagcggc cgcgttgacg
     9781 accacttcga gcgccatcag cactaccagc ccgatcacca gcagcaccac ggatcgactc
     9841 gccgtcagcc cgtcgatcac ggccttcatg gcgagcggct gtgctatccc cagcccggcc
     9901 gccaccagca tcagcagcag gccgagggcg agggcgcccc gatgcccggc gagcatctgc
     9961 cacagttggc gcggcatccg gtcctccttc gcacgagaac tcatggcccg accaggaatc
    10021 cggcttccct cagttggtcc gtcatgacgg tgatgtcgcg gcgcggcccg gccggatcga
    10081 tagcgtattc cgccgcgaag tcggtggcga tatcctcgac cgaacgtccc gacagcaggt
    10141 gccgcagtga atcgagaccg accgggttga gctgccagta gtgaccggtc cgcaagtgca
    10201 gcaataccgc gccgtccgat gtgccgacac tgagcacctg ccgatgcagt cggaaatctc
    10261 ctgtgcccgt acccatctcg gagtagtggt cgggatcggc cgcgacctgc gccggcgcga
    10321 cggtcagcat cggcgtgtag tgcccggcag gcatcggctc atcgatcatc cgcccttcgg
    10381 cctccaccca ggcgtgcgcg ccgaacggcg cggtgcacac accgagtcgc caggtgggcc
    10441 agactccgcg cacgcgacac agcagtgctg tcgcgatcga gcgctgtaga caaccgttga
    10501 cggcacaccg caggctgacc gccatgatcg cctgccgcgc acgggaagtc tggtcggcag
    10561 gggcgggacg cgcgccgcgc cgggcgaatt cgagcaccca ccgcagattc ttgggcggca
    10621 gtatggtcag cggtgccgcc accgcgaccg cgatgagtgg caaaaccctt tgccgccaag
    10681 gcaatcggat ccgctcgggt ggcgcgcacg gcgtactcac agcttcaccc ggacggtcgc
    10741 gacctgtcgc agccacagtt cgcagcccat agtcatctcc agattcggcg ccggatcgtc
    10801 gtccgcgccg ccgaccgggg tgtacaggta cctccgcagc gcatcgacgt cgatcaggcc
    10861 gcgcgtggcc aacgcggaat ccgcgaacag ttccagcagg tccggaacat gctgattcag
    10921 ggcgttttcg acctcgctgt cgtactcgcc cttggtgcgg cgatcaagga tcagatccgg
    10981 aacctgcccc cgcatggccg ccgccagcag cggtttgtag tgccaagggt tgaaccgttc
    11041 ttcgcagcgg accgcgagcg cggcctcgat cacccgatcg tccagatacg gaagatcaag
    11101 gcggagaccg ccattggcat aggtgcgaca caactgccgg aacagcggac cggcgaaacg
    11161 caggtaggtg agcgcctcgt gctgaccgcg atcatccgcc aggggcaccg cctcgtcggc
    11221 gatatcgcgc aggacccgcc gcgcggtgtg caccgcatcg gcggtggccc acggtgtgat
    11281 tcgcagcgga taggcccaac ccagctgcgg cgcattgggt ggtggcggcg gatcggtgag
    11341 atggtcggcg gtgtgccgcc accacgaact caggcttgca ccggtggcga gtgccaccat
    11401 ggtggacccc agcggccagc ggcccagcgc ccggcgtacg cggaggtctc gcaatgcccg
    11461 caacggattt cggcgcagca gcgtgtgcag gtaacccgct ccgccggaga acagttcgtc
    11521 gccgccgtgc ccggccagat gcaaagtggc cccgcgccgg accaactctt ggatctggtg
    11581 atccatggtg ttgaccccac gggtcagcgc atgcggcgcc tcggtatccg gcaggatata
    11641 cggcggctcg aaaacctttg gcccgtcctc gctttggaga tggatatagt cggcccgatc
    11701 cagaagtttc gccgcctcgc ccgcgtagaa ggggtcgtcg ttgatcgcgc tgctccccgt
    11761 ccggcggaag atcagcaagt tgggcgtgtg ctcggcggcg agaaagcaca gcgaggtgga
    11821 atccataccg cccgacagat ccgccgacaa ccgcccacgc gtcggcctgc gccatgccac
    11881 ggcctcccgc aatgcggccc gcacctgtcc cgacccctcg gcgatcgaca gatccggttc
    11941 cggcggtgtc caccagcgca ccgggcgcgc gcggtcctcg ccgtcgagca gcaggtagga
    12001 gtccggagcg atccgccgca caccgcgcca ccaggtgcgt tcgctgagcg gtggaatcag
    12061 ttgctggcag gcgatattca ccgcgagcat atcctcgtcc ggctcggcat cgatcatgac
    12121 cgccaatgtg tcggcccggt cgctcgcgat ggtgatgccg tcgagtcggg ccgtgcagac
    12181 ctgccgggtg ccggtgagcg ttccctgaaa tcggacccgc ccatgcaccg aggcgatgag
    12241 gtgcgcgctg cccggcagtg tgcgggcgag tgcgtcgaga tcggacggag tgcgaatacc
    12301 cgcggccgcc gccgtcaatt gctcgggacc gatcgggcac tccccgaata ccgcgacccg
    12361 cacgccaccc gcatcggcca cgaccagatt ctcggctgcc cagtgaccga tcaaccacgg
    12421 tcgtccggac gagtgatcga tgatcttcgg atcgtggtgg ggaacccgcc gtccggcgag
    12481 aacaccgccc ggtgagtcgg gaaggacgac aagactattg gtcagcgcgt acatgggcga
    12541 cctcgctggc agaaggggat gaggtaatac ggtgggaatc gaagggactc gatcccccac
    12601 cgtattcatc gtgcttctcg gaaccggaat cggctcccat acatgggatt acctcgctcg
    12661 acgccgacta gcccttcttg aaaccgaagg ttgtcgcgtc cttcttggtg tggatggtgc
    12721 cgaaggtgtc ggtggcaacg cgaccgactt tggcagcgac cggaggaaca taacgcttcg
    12781 caccggtccg agaggtgttc tgcatcggta ttctccattc tctcgttgtc actttccttt
    12841 tcccccgtgt cgtcgcgatt ctccgcgcga cccggaagct ctcgcctgcg attgacacag
    12901 cagtggcgac agtttcggat gaagctgaca gtcgaatcca ggatgatcac accggccgca
    12961 ccaacatatc ggtcgccacg gtcgcagcgt ctcagtgaca cgcccacgtt tcgcctggtg
    13021 cgtgtcccgt gaagaaggag aggtccgctc ggcgtcgaag atcctccccg gttggggaat
    13081 tcgcgccgga tccagcgatg gttccgcggc gtgacgcgtc tgcaggacct gaggtgtcgc
    13141 cgcagcagat cgacatcgat caggcaggag gggatcaagg caatacggtg gggatcgaaa
    13201 ggactcgatc cccaccgtat tcatcgtgct tctcggagcc ggaatcggct cccacgcatg
    13261 gggttacctc gctcgccccc tatcagccct tcttgaagcc ccaggttgtc gcgtccttct
    13321 gggtgtggat cgtgccgaag gtgtcggtgg caacgcgacc gactttggca gcgaccggag
    13381 gaacataacg cttcgcaccg gtccgagagg tgttctgcat cggtattctc cattctctcg
    13441 ttgtcacttt ccttttcctc cacgtcatcg cgatgttccg cgcgacccgg aagctctcgc
    13501 ctgtgatcga tacagcagtg gcagcagatc gagatgagga tggcgtccga atccaggatg
    13561 atcacatcgg ccgcaccaac atatcggccg ccaatgcggc cgcgtatccg tgacacacct
    13621 ttctttcatc gccgcttcga agtaggcgtg cgctgtcgac gtcgagatat cgaatgcttg
    13681 ggcgagtgcg tcccaatcga gttcaccgtg agtttgtcga gcgcgcaact cttcaggccc
    13741 ggccacaccg ccttcgacag gcgcacggtg tccaggaccg tgagcggcta ccagtcgggt
    13801 agatgagggg tcagtccctt ctgctcgacg ttcgcgttgt gcgccaccag ggttcgcccg
    13861 aacatgagac ggccgatcga cggggagacc tgcctccgtt ccggacagcg caaagcagcg
    13921 tcggcgacaa cgggtttcgt cgaactcgtt gagcggaggc ccggtttgca ccggccgatc
    13981 ggctcagcga gccgatggat ggcccgtcac acccggaggt agggacagat gcacagcggc
    14041 gtggtaatag ccctcggtct ccttcccggc ggggtcagca ccggcttcgg tgacggcggc
    14101 gatggcgtac cgctgctcat cgaggtcggt gaatcggcgc tggaggaccg tgcgcgccgg
    14161 atcgacctcg gtgaccagac cgtactcggc cagggcgtcg gcgatgggcc ggtaggaacc
    14221 ggtccgcagc acgaacgcgg cgacccacac cggttcgact gccgcgccga gcaattgctg
    14281 aaaggtgcgc gcggtcagga aactcgcgcc accggtcacg gtgatcaacc cggcgggacc
    14341 tgccgcccgt agcagggcag gtgacgcggc gccggtttcc aggttctcga cgaagcccgc
    14401 gtcgagcaga cccacggcca gcgcgtagtc gatcgcggga gcggcgatgt ccaccccgac
    14461 caccggtacg gcatcgtcac ggcgacgtgc ggcgtagaac tccttgtcgg actcgatcaa
    14521 ttcgaccgtg tccagctcgg ctatctgcgg aagggtgtag cgggcgtaga ggtcggcgag
    14581 ggtcagatcg tggttgagca gcgccgcatt gatgccgtac gagcagcaca ggtccaccac
    14641 cgtcaccggt cccgactgtg cgcgcgcggc gaccagacgg cggaataccg cctgggcatg
    14701 atgcggggtc cggtagtcga accgaccgag actgccgaag tatccgcgcg ggtcgggttg
    14761 atcgtagatg tcgtcgaaag gtgttctgcc tccgaggatt tgcgacatac ccgatcttgg
    14821 cacgccgggt ccaccgagga gcgcggttgg actcgatcgg gccacaatcg aatccttcag
    14881 tccggctgga agaatgcgag cattcggcgg ctcgcgtccg gcgctgtcag gagttcctgc
    14941 acgcgggccg acattcgggc ggcagcgcct gtgcgttcga acatttcgcg ttcgtaggtt
    15001 gcgacggcgg tggggatgtc gccctggtgt gcggccagtg cgagaccgag ggaggcgcca
    15061 tcgagcaggg ccatattggc gccctcgccc accggcggca tcaggtgcgc ggcatcgccg
    15121 accagggtgc ggtccggctg tgacggccag atcaggccga ccgggagagc actgatcgac
    15181 cggggcgcca ccaagtcgtc gcaggccgcg atcaatgcgg tgaaccgtgc gtcccagccg
    15241 gggagcagtt cgatcagtcg cgctcggacg gcggctgggt cgtcgaatgg gattgcgctg
    15301 gtggcgaacc agttttcggg ggtgttgtag aagcagacgc cgatgcggac gcggccgtcg
    15361 ccgttgcgtt gcgctgccaa cgacaatccg ttgccgatca cccagaagtt gccgcgcccg
    15421 accatcgccg cgagttcggg atgcgtgcgg tcgatatcgg gaatgccgac ctcgacgaca
    15481 ttctgaccga gatgggccgg gcgggcgtcg gtgagcagcg cccggaccct ggactgtgcg
    15541 ccgtccgcgc cgaccagtag gtcataggtc gcgctgctgc cgtcggcgaa gcgcagcagg
    15601 ccgttgtcgg cggaattgaa cgcgtgcccc cagcgcaccg cgtccgcggg cagggaatcc
    15661 agcagcatgt cacgcagatc ggcgcggtcg acctcgggac ggtcgagggg ggcgtcctcg
    15721 ggggtgtcct gccgcagcag caaggtgccg tccggttcca gcaggcgcat atcctgccct
    15781 tcgctgcggg cgatcgcatg gaaccggtcg atcagccctg cttcgcgcag tgctcgctgc
    15841 ccggaatgga tgtcgagcat gccgccttga ccgcgggcgg ctcgcgagga ttcgcgttca
    15901 tagacgacgg cctcgatacc gtgtaggtgc aacaccctgg cgagggcgag tccgcccatt
    15961 ccggctccga cgatggcgat gatcatgact acccttcgat acactggctc gtgtcgatac
    16021 actgtatcgg accatgcgat gtatcgtcag cgacatgttg gtgtgggagc ggccggagcc
    16081 gcaggatcga ccggtgcctg ccccattgag ccgagagcgg atcgtcggtg cggcaatccg
    16141 actggccgac gaggatgggc tcgcggcggt ttcactgcgc aaagtcgctg ccgcgctgaa
    16201 cgtagggccg atgcgactct acggctatat cgccaccaag gaggagttgc tcgacctgat
    16261 ggtcgatgcg gtccatgccg agatccgacc gatcggagac ggttggcgag aagtgctgcg
    16321 gtccctcgcc gaaaccactc gacaggcagc tcatcagcac gaatggttcg ccgacctgct
    16381 cggtggccga ccccagctcg gaccgcacgc cctggccggg ggcgaggccg tggtcgccgc
    16441 gatgggcggt gtcgacgtgg ataccgtcat gccggtggtc gccgcggtca acgcgtatgt
    16501 gatcggcgcg gtgcgtggcg agatcaccga gcgccgcgcc gaacgaacca ccggaatgga
    16561 tacgcggcag tggcaggccg ccttcgggcc atatttggag cggaccttcg cgaccggccg
    16621 ataccccgca ctggccacgg tcatccgcga cggcgcccac ctggacgccg accagacctt
    16681 tgacgtcggc ctcgaactcc tcctcgacgg catccaatcc cgcatctcga gctgatgccg
    16741 caccggctac agcgggcggc ctcgaaccgg cttgcgccac acggaaatgt gcttggtgga
    16801 gtcggcggcg aacggcgtcc cggcccagtc cgcgtagcga tgctcgggct cgagaccggc
    16861 gatgcgtgcc atcaggtcga gctcggcggg ccaggcgtag cggtggcggg aggtatcgcg
    16921 gcggtagtgg tcgccgtcac gggtgaagtg atgtgagacg aggagctgct cgaccacgtc
    16981 gatggtgtcg aagccaagat gtcgcgcgga cacgtcgaaa gggaccgcga cctgaccggg
    17041 tggcagcaac cgcagcggag gcacctcgag ttcgatgacg aagcggccac cgggcctcaa
    17101 atgccgtgcg gcattgcgga aacaccgcac ctgcgcgtcc tgggtgagca ggttggaaat
    17161 ggtgttgtag acgagataca ccagggcgaa ctcgccgggg acgacggtgg tggccatatc
    17221 cccgatggtt accgggaggg tgtcctggtc gatcttgcgg cgcagcaccg cgaccatatg
    17281 ctcggagagt tcgatgcccg cgaccggcac gccgcgtccg cgcagcggga tgccgacccg
    17341 cccggttccg atggcgaact ccagtgcccg accgtccccg gcgagctcgg cgaggaaatc
    17401 cagggtcggt gcgagaacag ccgccgagga catgaccgtc tcctcggcgt cgtagcgctc
    17461 ggcgctcgcc cgtccccaca gctcgctatc ggtcacagcc gaccactctg cccgccgccg
    17521 cgaacgctgt cgacccattt accgctgcgg gcaggcggtg cacactcggc ccgagatcgg
    17581 ttgcaccgca acatctcagc cgtccggagc catgcatcgg attgcgtcct cgggtggagc
    17641 aggcccgcag aagatggaag tcttgtcgga tgaccgagca cgcagccaac gaaacgatcg
    17701 tgcccgcgac cacacgggat ttgcatgagg tggtcgagaa ctacatccga ctgagagcca
    17761 ttacctcgcc gggcaatcaa ggctcgatcg gctttcaccg aagtctcggc ttcgaagcaa
    17821 atctcgtcgc cgactacaac gggccgggaa tggcccgaat cgtcttcagc agggatctgt
    17881 aatacgcccg agggattcca cgcttcgacc gttcgcactc gtaacatccc ggtatccgca
    17941 tccgatgatc ggatgacatt tcgagaggat atcgaatgaa aacaacgaca atcgccgcca
    18001 cccgggtagc ggccgcggcc gcatcggttc tgggtttcgc cgcagtaatc ggcaccggta
    18061 ccgcccaagc ctccgcccaa gattgcaccg tcacgcgaga cctgttcggc gcgacggcgg
    18121 catgccgcga caccgaggca ccggcaggca gggagtacac cctggtcgtc gaatgcgtcg
    18181 gcctgcacgg tatcccgaac gccttcccgc tcatgaccat cggcccctac cagggttcat
    18241 ggggtggctc cttcggcccg tccggccagg gcacggcttc atgcttgggt cccaccagtg
    18301 tcggaacagt caccaatgcc tacgtagcgg tataccgcga ctgatcaaat gcggcgcctt
    18361 ttcgagacca gccgccgcca ttgggccaat ttcaaatggc aaaccccgag ggatgggtga
    18421 gaaatgtttc gtcggccagg aattggcgat cgtgctcgag aacattcgcg aggtgcgaga
    18481 gcgatccgcg ctgataacga ggcatgatcc acaacgggat tcgcagtcct acagcgtgtc
    18541 tcgccgatcc gaggcaggta tccccggatg gaccgttgtg gctcggtccc tccggtgcgt
    18601 tgcggggcag atttccagtg ccatcaaaac gtcgtcgacg tagcggtctt cgatcaggaa
    18661 ctggccgacg agagtgccct cgatccgaaa gccgtgtgcg agatacagct tctgagcacg
    18721 cacgttggtg cccaatactc gcagggtgat tcgtcgggcg aggcgttcga cggccgcggc
    18781 gcgggcggcg tcgagcagca ggtggccgat gccgcgtctt tggtggtgtg gggcgacggc
    18841 gaggccgttg atctcctgga catgtccgct ggaggcccgc atcggagccg gccggagttt
    18901 cacatatccg aggatgtggt tgtcctcgtg cgcgagcagc acgttgcgcg gtgcggtccc
    18961 ctcgtcgaag aagggcgtgt ccgacggcca gagcgggatg ggatgcactt gcctcgacca
    19021 ggtggcgtgg tcgatggcgg ccagtgcccg ttcgtcgttt tcggtggcgg tgcggatggc
    19081 gattccgtcc atgcgtcacg atcctgtcgc gagccggtcc ggccggcaag cgatttcgcg
    19141 aatccaccga tcggctcgca ccgcagtgca aggtccgcgc aagccgggtg acagatccgg
    19201 cgcgcacagt gggtccatgc gaacaaccga cagcgtcgcc tcggccgacg gcacccgcat
    19261 cgtcttccac acgctcggcg acgggcctcc gctggtgatc gtgcacggcg cgctggtcac
    19321 gacggaggcg tatcgcccga tggccgaact gctcgccacc agctatcgag tagtgctcat
    19381 cggtcgacgc gactacgctc cgagcggaaa cggcccgcgg ccaagcactt tcatcgatgc
    19441 gccgtttccg acagcgccct gcgcgccatg ggagcagcca tggccgaccg cgcgccggga
    19501 ctgatcgccg acctcgaatg cctcaccgcc atggatccgg acccgaaccg ctggtccgcc
    19561 acgaccgcac cggggctact gctggcaggc tcgtcgagcg accggtacgg gctggaaagc
    19621 atggcgaaac tcgaggcggc cctgccgaat tcacagttca cggtgctgga agggctgacc
    19681 cacaatcccg atgatttcac tccgatcgcg accgccatga gcgaattctt ccgctaggtt
    19741 ccgaggcccg cggtcgagtc cgagcgagca ctccttcctt cccaagtcga tcaagtccca
    19801 aaagagatcc cagataacca ctttgaagtc gtgctcactg aaacccggtg cgagcaccaa
    19861 acgtttgaac aactgaggca tgccgctcac cctaatctcc cggcaaccac tggaaacgcc
    19921 ccgaataccg aggggcgcac ccgcccgcat cgacgaaacc gccacgcggt cttccggatt
    19981 cgtcgcgccg tactcggaca tccgcccgcc gacggcgagg ctatttggaa tgcgctgcgc
    20041 cgctggataa tccaggacgt ctcgtacgaa gggaatagag tgcgaacccg gccgcgacca
    20101 tgagaatcgg ccaggtgatc aagccgagcg ggcctacgat cagcgggtcg gggatgtggt
    20161 cgcgggcggc gaagaatcgc ggcagacgca gggcgaactc attgagacct gcatgcgccg
    20221 cgaccgcggg ccacaccgag cgcgtgtgga tccggatcgc cgcgatcacc gcgccgatac
    20281 cgaccgcggc gccgacggcc atcggaatcg cgacatacag cggatggccc ggatagctgc
    20341 ccccgagcgc tgtcatcggc agatgccaca gcccccacag cacaccgccc acgccgatgc
    20401 cgagcaccgg tccgtagcga aaggtcaacc gcggcagcat atatccctgc cagccgatct
    20461 cctcgccgag atacagcggc agcgagatca acgccgagac cagcatggtc agcagcggcg
    20521 cccaactctg cggccagccg ggccggaaga ccccgatcgc ggccgcgggc agtaacccta
    20581 ccgccgcgat cgccggaaag atcaccccgg cgcccacaca ttgggcaagg acccgcggcc
    20641 ccggcagacc cagcgagagc acctgcggca cggcgcgcca cgggtgccgc cacctggtga
    20701 gcacgacagc gaccgtcgcc gggaccacca tcatcgtgaa caggcagacc gtcgccagcg
    20761 tggtcgcctc ctgccccggc gccacccgcc ggaatccggt cacccacagc ggcgccgcca
    20821 ccagccaggc gccgaggtag gcggcgacga ggaagatcac caactcccgg ccggatcgtc
    20881 ggcgcgagtc gcctgctcgc ggtgagagca ccgcattccc attcgtcatg ttcggcaacg
    20941 gtaggcaccg cgcagcgccc gcgcggtgca gcggcctgcc cctgcgaggg tggagcccgc
    21001 tacaccgcgg caatcggcgc ggcgtgcgag actgcgggga tgtcgttcgc gatgtggtgg
    21061 gttcgatggc gtggcgcgct ggtcgacggc gtgcgcaccc tcgcgctcgg cctgtacgcg
    21121 atcctcgcgc tcccgctact cgtctacacc gccgtcacct gcctggtcgg catcggattc
    21181 gtgctcgtcc cgccgcaact gtgggtgctc gggcgggtcg ccgatgccga gcgtcgccgg
    21241 atcgcgcgcc gccgggggac gatcgcggaa acggtggatc ggcccttccg gtggttgccc
    21301 gcgctcgtca ccgacccgac ggtgtggcgc gaactgcgct gggtcgcgtt cctcgcggtc
    21361 ggcgggaccg tgctcggcgc tctgggcacc ggcgtcgcgg ttctgccgtt gctcgccttc
    21421 gcggcgatct ggctgtggtg gctgttccct gccgacgacc cgatccgcat cgtggccaat
    21481 atcccgatcg cgggctggcc gtccgcactg accatcggcg tcgcccagtg cgcgatcacc
    21541 gccgcggtgg ccgtcgcggc cggacccgca ctcggccgcg ccggactgtg gctgtccaac
    21601 gcgggtctgc gagtgagcgc gaaaaagcga ctgacgcagc aggtagccgc actgcggcgg
    21661 acccgttcgg gggcggtcga cgcgcacacc gccgatttgc ggcgcatcga acgcgatctg
    21721 catgacggaa cccaggcgca cctggtcgcc ctcgcgctgc ggctgggact ggcctcgcgg
    21781 gcgctcgacc gcgatccgtc ggcggtcggc ccgctgctcg aggaggccag ggcaggcgcg
    21841 gaggccgcga tgagcgacct gcggaccgtc ctgcgcacta cctatccgcc catcctcgcc
    21901 gatcaggggc tcgacggcgc ggtggccgcg gtggcggcgc ggtgcaccgt gccgaccgcg
    21961 gtgcgggtgg aactcgaccg cgaactcccg gccgcggtcg aggcggcggt gtatttcgtg
    22021 gtcaccgagg cgctgaccaa tatcgcgcgg cacgcgggcg cgacctcggc cgcggtcgag
    22081 gtgcggacca ccgccgacgg tgtggcggtg gagatccgcg acaacggtcg cggcggcgtg
    22141 gatcccgccc gcgggaccgg cgtggcgggc atgctccgcc gcctggaagc cctggacggc
    22201 gtgctcaccg tggacagtcc gccgggcggg ccgacggtgc tgcgggcggt gtgcccgtgc
    22261 ggatagtcat cgccgaggac aatgtcgtcc tggcccaggg gcttgtgctg ctgctgcgcc
    22321 aggaggggca cgaggtcgcg gccgtcacca gcgacgtcga gacattcatt gccgccgtga
    22381 tcgcgcaccg acccgatgtc accatcgtcg acgtccggct gccgccgacc ttccgccacg
    22441 agggcattca cgccgcgctg cgagcgcgcg cggagattcc gggacagccg gtcctggtgt
    22501 tctcgcagta cgtcgagcac agttacgcgc ggga
//
