LOCUS       NZ_QZFU01000018        23281 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Nocardia panacis strain YIM PH 21724 NODE_27, whole genome shotgun
            sequence.
ACCESSION   NZ_QZFU01000018
VERSION     NZ_QZFU01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia panacis
  ORGANISM  Nocardia panacis
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 122947)
  AUTHORS   Miao,C.
  TITLE     YIM PH21274 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 122947)
  AUTHORS   Miao,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2018) Yunnan University, Yunnan Institute of
            Microbiology, 121, Kunming 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 29.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003598715.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 03:06:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,880
            CDSs (total)                      :: 6,804
            Genes (coding)                    :: 6,707
            CDSs (with protein)               :: 6,707
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 32 of 97
            Pseudo Genes (incomplete)         :: 82 of 97
            Pseudo Genes (internal stop)      :: 7 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:26:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 92075
            Orig. end                         :: 115356
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QZFU01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23281
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23281
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23281
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:13281](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13281
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(197..1321)
                     /locus_tag="D5S18_RS14465"
                     /old_locus_tag="D5S18_14465"
     CDS             complement(197..1321)
                     /NRPS_PKS="Domain: Aminotran_5 (18-324). E-value: 8.3e-34.
                     Score: 109.0. Matches aSDomain:
                     nrpspksdomains_D5S18_RS14465_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014985336.1"
                     /locus_tag="D5S18_RS14465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14465"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_120041192.1"
                     /sec_met_domain="Aminotran_5 (E-value: 8.6e-30, bitscore:
                     96.6, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDRIAALRAEFPVLRSGIYLNSNSTGAIPRDVEQVLRRYWDTLR
                     DWRDDAWSGWLDELDGYLRALAEFLGAPVDSIVTEANLTTLLGRLATCFDFDGPRREVL
                     ITNREFPTVPFLWRGFARYGAQVEIADFDTGAVLAALSARTKLVCVAHGSYTTGGLLDL
                     NRIVAAAHAVGAEVIVDAFQTVGTVPLNMGTLGVDYLLGGSHKWLCGAHTAFLYIRPDL
                     IPTLRPAATGWFAGADPLTFRPTEDWADSARRLAGGTPIPLTAMISRLGLDLLATFGAE
                     AIRDHSLRCTDRVIARADAAGIPIRTPRQHECRGGIVTLAFPGDRVVKQRLADREMVCS
                     WRDGLRIAPHIYNTLDEVDAFMDALIAARQELSE"
     aSDomain        complement(350..1267)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_D5S18_RS14465_Aminotran_5.1"
                     /evalue="8.30E-34"
                     /label="D5S18_RS14465_Aminotran_5.1"
                     /locus_tag="D5S18_RS14465"
                     /protein_end="324"
                     /protein_start="18"
                     /score="109.0"
                     /tool="antismash"
                     /translation="IYLNSNSTGAIPRDVEQVLRRYWDTLRDWRDDAWSGWLDELDGYL
                     RALAEFLGAPVDSIVTEANLTTLLGRLATCFDFDGPRREVLITNREFPTVPFLWRGFAR
                     YGAQVEIADFDTGAVLAALSARTKLVCVAHGSYTTGGLLDLNRIVAAAHAVGAEVIVDA
                     FQTVGTVPLNMGTLGVDYLLGGSHKWLCGAHTAFLYIRPDLIPTLRPAATGWFAGADPL
                     TFRPTEDWADSARRLAGGTPIPLTAMISRLGLDLLATFGAEAIRDHSLRCTDRVIARAD
                     AAGIPIRTPRQHECRGGIVTLAFPG"
     gene            complement(1318..2106)
                     /locus_tag="D5S18_RS14470"
                     /old_locus_tag="D5S18_14470"
     CDS             complement(1318..2106)
                     /GO_function="GO:0004833 - tryptophan 2,3-dioxygenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0019441 - tryptophan catabolic process to
                     kynurenine [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014985335.1"
                     /locus_tag="D5S18_RS14470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14470"
                     /product="tryptophan 2,3-dioxygenase family protein"
                     /protein_id="WP_120041194.1"
                     /transl_table=11
                     /translation="MGDETEATRLRTAIGKPIFNPVLKSWVGAGVTDYEMYLRTSDLLA
                     LQTAHEDLTDSDELMFQIVHQAQEIWLKLLAHELVDVVGELDSHALWEVSARLARVARI
                     ADCLAEELRVLETMTPDTYQVIRRSLGQGSGQESPGFNAVLTAAEYVAAALDRLLEREG
                     IALTDVYGATPPQHLKRVCELLVDLDERFQMWLVGHFMLVRRTIGVGRGVNALDGVPTA
                     VLTGRMTKPLFRKLWQSRTELTASWHAGGGYAPGAERSSR"
     gene            2352..4301
                     /locus_tag="D5S18_RS14475"
                     /old_locus_tag="D5S18_14475"
     CDS             2352..4301
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046106.1"
                     /locus_tag="D5S18_RS14475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14475"
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="WP_120041196.1"
                     /transl_table=11
                     /translation="MSDIGRERRRRWAEEQLAGLPHLSAPQRRFLSVPLMESGWQLLVH
                     RSGVLRGRPVAFAVGRTGVYALVFTDDIPEIEQLRRIRRYAEETFGGLLLGRRQYVPHM
                     LEVMLLMGKAVRTQAHDPYLAVDETTMRSTLLNGEQKLTPQRARDCVAAVLARDQQYSW
                     ISTANAPRAEITSADGLFGVEELREDERTRVLRRPFEEWMTFLDPDQLGYVSVNFNGPA
                     RFSGPAGTGKTVVALHRMARFAKNNPGKLLFTSFVKTLPAHHQSGFARIAERHADRAEF
                     IGLHAWAMRFLNRRRVKFDLAEDGQVVTAFARAWSAGRHELSRIPDTDRNYWEDEVKRV
                     IKGRGIDSFDDYEKISRPGRDGVRLSGPRKKLVWDNFYLPYQARLAEKNLDDFNDIVRK
                     AIAELRIRPLVGAEKFGMVVVDEVQDFTLQELRLVLEIAGGGSEAQLLLVGDGQQQVYS
                     GGWKLSDAGIPLAGRGRVLRTNFRNRAAILRYAKRIEAADTVDDLDGGTGFVLRDSDGV
                     LDGGTVIEKSIPRADLDTELVRAITESGMTASNCAVLVNTNHEAAHYQQVLESAGLSAL
                     LLEHYNGTQHSAIEVGTVYRAKGLDFAAVFRIAEPIPRGNNPADRDRAELLARQHLVAV
                     TRARDYLWVGLVGD"
     gene            complement(4227..7033)
                     /locus_tag="D5S18_RS14480"
                     /old_locus_tag="D5S18_14480"
                     /pseudo=""
     CDS             complement(4227..7033)
                     /GO_function="GO:0016831 - carboxy-lyase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019736239.1"
                     /locus_tag="D5S18_RS14480"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14480"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHRDGKRPKGLSVSALAAVANPSYSRIDTWNLLDDACRRLAEVNR
                     AGLDTAHETAVVRRLLDRLGAYERYWLYPGAARLAAFRGYLADLATARLTEEVSLAVRL
                     LSEYGDGATAFNNSAPLADQELVARTEQRQYFTVVLGDDSPPESPDSLAERLRALRDPS
                     DDVRFELLVVSSIEDAIAAVALNGEVQAAIIRHDLPLRSRDRVPLMTTLLGVNTGVAVT
                     ERTANWVECGEWIRELRPHIDLYLLTDESIAAEPEDEPNVYDRTFYRLNDVTDLYSTVL
                     AGFRLRFATPFFDALRAYAAAPVGQFHALPVARGASIFNSKSLQDMGEFYGRNIFMAET
                     SSTSGGLDSLLDPHGTIRTAMDKAARTWRANQTYFVTNGTSTANKIVVQALTRPGDIVL
                     IDRNCHKSHHYGLVLAGAYPLYLDAYPLEPFAMYGAVPLHTIKRVLLDLEAAGQLDRVR
                     MLLLTNCTFDGIVYNPRRVMEEVLAIKPDICFLWDEAWYAFATAVPWARQRTAMVAAEQ
                     LEAMLSSPEYAEDYRTWRASMQGIDRAEWHNHWLLPDPERARIRV"
     misc_feature    complement(7224..7239)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            7243..7752
                     /locus_tag="D5S18_RS14490"
                     /old_locus_tag="D5S18_14490"
     CDS             7243..7752
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014987808.1"
                     /locus_tag="D5S18_RS14490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14490"
                     /product="N-acetyltransferase"
                     /protein_id="WP_239003766.1"
                     /transl_table=11
                     /translation="MTISDEVHHVQDDRKVTLRRVTGRTVGAICDLSETLTEEQRDMVA
                     DNAISIAEAHFSENAWFRAIYVGESPAGFVMLHTGYDYDEGFDCHGVFLWRMMVAGPFQ
                     SKGVGRKAIDLIVADLKARGINELYTSYGQGAAGPEPFYKGLGFLPTGDFYGEGEHREI
                     GVVLRW"
     gene            complement(7782..8648)
                     /locus_tag="D5S18_RS14495"
                     /old_locus_tag="D5S18_14495"
     CDS             complement(7782..8648)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007537465.1"
                     /locus_tag="D5S18_RS14495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14495"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_120041200.1"
                     /transl_table=11
                     /translation="MFDPELLRTFLAVERAGGFTAAGRLLGLRQSTVSGHIARLEQATG
                     RELIRRDTRNLALTADGAAMVGFARAILDAQARAAAYFSGSTLTGLIRLGASDDVMALE
                     LPDILMEFQRTHPGVDLELTVGISEHLKTRMAAGELDLVFGKRLPGERHGELLWRDKLT
                     WAGRPATPPLEDPVPLVTYPAPSLTRRRALAALEQAGRTWRIACVSDSLLGLRAAALAG
                     LGVVVHAESVLPEGLSPLPDPALPELGDLEFVLMHRRTRRTDPEQALSDLIAANTGRLR
                     HPAIDAP"
     misc_feature    8660..8674
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     gene            8734..9798
                     /locus_tag="D5S18_RS14500"
                     /old_locus_tag="D5S18_14500"
     CDS             8734..9798
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007301452.1"
                     /locus_tag="D5S18_RS14500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14500"
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="WP_120041201.1"
                     /transl_table=11
                     /translation="MKLLAKLHIDGFMLGILATVAVAALLPARGTAADALDWATKIAIA
                     VLFFLYGARLAPREALAGLRHWRLHASVLGTTFVLFPLLGLLLRPLSPSLLPADLYTGV
                     LFLCLVPSTVQSSIAFTSMARGNVAGAVVGASLSNLVGVFVTPLLVVLLMKTTGEVRVP
                     LGSVALIVVQLLVPFLAGQVLRPRLTWLLRHAAVVGSVDRGSVYLVVYAAFSAGMTEGI
                     WKSLSPTTLLITAVVCACLLAFVLCATTLSARLFGFARADRIVVTFCGSKKSLATGLPM
                     ASVLFAGHPIGMIVLPLMLFHQIQLFTCAVLAQRYARHVEVDPLGNAPSESGTVDELGQ
                     SGAMSRMGVSVDRS"
     misc_feature    8743..8745
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..12256
                     /locus_tag="D5S18_RS14505"
                     /old_locus_tag="D5S18_14505"
     CDS             10001..12256
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983664.1"
                     /locus_tag="D5S18_RS14505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14505"
                     /product="germacradienol/geosmin synthase"
                     /protein_id="WP_203236742.1"
                     /sec_met_domain="T1TS (E-value: 6.5e-81, bitscore: 265.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIEPFQLPEFYMSYPARLNPHVAAARAHTREWAREMGFFEDQQG
                     VHIWSEQDLERHDYGLLCAYTHPDCDERELNLITDWYTWVFYFDDHFLELYKRTRDTAG
                     AKQYLDRLRDFTPVGGGAPPEPTNPVERGLADLWTRTAPAMSPAWQRRFAASNWALLVE
                     SRWELANIAAGRIANPIEYFEMRRKVGGAPWSADLVEHAAGAELPPRLVDSRPLRVLRD
                     TFADAVHLRNDIFSYEREVRQEGENANAILVVENYFGYPTQRAATAVNDMVTSRMQQFE
                     HTALTEVPALLIESAATPQEQWAVAAYVKGLQDWQSGGHEWHMRSSRYMNAHANTERVG
                     LPFLSATIGLTKPSLDSLGPKRVKQFPPSLVEHAGSSGTQGLSLPFEVRINPLLDAARE
                     HTVRWAQEIGLFEPVPGAARPLWRERDLRDFDFALATAGMGPDAGQADLDTATDWLTWG
                     TYIDDYYLEVFGHGRDVAGAKAQGARLLEFVPVDLGAAPIPLTCMERGLAELWPRTTAA
                     MGTAQRERFRRALAQFFAGLTWETSNFALNRIPDPIDQIEMRRLAFGGDLTMGLARLSY
                     DGGVSDEVEQSRTVRDMNTIACDVAMLTNCLFSYQKEIRFEGDPHNTVRVLRNFFDCEH
                     AEAERLVGILISTRVEQFQRLVEHELPALYAEYELDRRARQDLTRRAANLRDYMAGILN
                     WHQGCRRYTEPELLRRFRPELFGSGLGARTPGLGAARLDALTARMGEPFRSPTGAPS"
     gene            12253..13281
                     /locus_tag="D5S18_RS14510"
                     /old_locus_tag="D5S18_14510"
     CDS             12253..13281
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014983665.1"
                     /locus_tag="D5S18_RS14510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14510"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_120041203.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-55, bitscore:
                     181.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVVSVSPTQPPTEILARTRKLVEPMLREAIAALPDPLRRMAGY
                     HFGWWDVRGNPAPGESGKMLRPALTVSACLACGGVPEDAVPAAVAVELIHNFTLIHDDV
                     MDGDTLRHARPTVWTIWGIPDAVLLGDALHAVAAELLVRAMPHGVGAQALQRLESAVIE
                     LCRGQHEDCHGQSGSGATIADCERMEMGKTGALMGCACALGALAAGAAPATVAALDRCG
                     RELGLAFQFTDDLIGIWGDPLVSGKPTSDLARRKRSMPVVAALCSQTAQAAELARIYGG
                     RDPMSPTDIARAAELIEEAGGRNWTQRQADRHIQAALCELPDARTAADLIALACLVTHR
                     NR"
     misc_feature    13313..13326
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(13324..13344)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 21.29"
                     /tool="antismash"
     misc_feature    13336..13352
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 21.7"
                     /tool="antismash"
     gene            13399..14703
                     /locus_tag="D5S18_RS14515"
                     /old_locus_tag="D5S18_14515"
     CDS             13399..14703
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS14515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_14515"
                     /product="hypothetical protein"
                     /protein_id="WP_120041206.1"
                     /transl_table=11
                     /translation="MSAVTSESDTVREESPSENPWTAAQKVGFRLFFALGSGLLVYVLF
                     TNMATISVVLLPLKVLLAKIGGYLVGDGSVTSQLGRGDGLGDWYGMFAVVVLAIIAAVV
                     WTLLDKRRDNYRKLGRALFEVTRFAVAVQLINYGLGKAIPIQMGFMNQPIYRLVPVGDL
                     SLMDTLWGFMGASNAYTIVAGLVELSAGLMLLWRRTWLLGSLVGVVAMAQVFLLNLTYD
                     VPVKMVAGTLLAASICLSAPFWTSLARVILNTGPVRPRELWDAPGGPRTRKWALRIGYF
                     YVVVQTALMGVLFGTALHDMHTVRSGLDGVWQATSVRIDGSPARLNRGAPEPWANVAIN
                     DRPGDYTAFASQDPFGHTDRWALKITDTTLEIRKRLSDRPLEIRYRWDDEHTLVLTGTL
                     DGHEFEGKYHRRAMKSSESGFRWVQPDLDPDVPKF"
     gene            complement(14720..15232)
                     /locus_tag="D5S18_RS14520"
                     /old_locus_tag="D5S18_14520"
     CDS             complement(14720..15232)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018159670.1"
                     /locus_tag="D5S18_RS14520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14520"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_120041208.1"
                     /transl_table=11
                     /translation="MPELIAPTVALHAAWLAAHEEWGPGSHEDGFGLLWYEKVDTEEGF
                     AAWVARMNNQSGHGRADGEYSTYRWIVEDGQVLGGIVLRHDYSDLGHIGYGIRPSARRR
                     KLATWALARMLDEARAAGLPRVLVVCAVDNIASARTIERNGGVLEGIRQTDIGPARRYW
                     IELGMPD"
     gene            15502..15768
                     /locus_tag="D5S18_RS35335"
     CDS             15502..15768
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS35335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_203236743.1"
                     /transl_table=11
                     /translation="MAAIRHEIVINAAPTRIWDVLADVGAVHERLLPGRVVDTRIEGSE
                     RFLTFPDGHVIEGDAFRAALPRQRVSERSCVARRASRGSSPPP"
     misc_feature    complement(15788..15801)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            16105..17340
                     /locus_tag="D5S18_RS14530"
                     /old_locus_tag="D5S18_14530"
     CDS             16105..17340
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005196740.1"
                     /locus_tag="D5S18_RS14530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14530"
                     /product="aldolase/citrate lyase family protein"
                     /protein_id="WP_120041210.1"
                     /transl_table=11
                     /translation="MQDVGGDALGDELDRRLSGWDRELAEKYPGDRGVRQPVHTVYVPG
                     DRFVPETARLWGLEALRMLGRHDLPDVPGLDAAAAAEIRHRVEVKLAIEPIEDLRIDFE
                     DGYGRRPDAVEDADVRAAARALAISVRGNAGAPFHGLRFKSFEASTRRRGLRTLRLFLG
                     TLIENDGLAPGFVVTLPKVTAPVQVEAMAATCAALEREFGLPSGRLGFEIQIETPQAIT
                     GPDGAAAVARMIHAAAGRCTGLHYGTYDYSAGLGIAAAYQSLEHPAADHAKAVMQVAAA
                     GTGVHLSDGSTNVVPVGNQVGSAWTLHARLVRRSLERGYYQGWDLHPAQLPTRYLATYA
                     FFRAGLPQAVARLRAYLHGGDSGFLDEPATAAALAGFVRRGLDCGALDAGDLDGLDPAR
                     LAELSRRAPAAQ"
     gene            17350..17586
                     /locus_tag="D5S18_RS14535"
                     /old_locus_tag="D5S18_14535"
     CDS             17350..17586
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS14535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_14535"
                     /product="hypothetical protein"
                     /protein_id="WP_120041212.1"
                     /transl_table=11
                     /translation="MRMRAEFTTEPFHGEGDPPPHATAALRVAESLGLTCDFGPLGTAV
                     AGRDAILLPALGAILAAAFDSGATGVTLRVERD"
     gene            17590..17949
                     /locus_tag="D5S18_RS14540"
                     /old_locus_tag="D5S18_14540"
     CDS             17590..17949
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024705.4"
                     /locus_tag="D5S18_RS14540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14540"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_203236744.1"
                     /transl_table=11
                     /translation="MDGSHPVLVAIAPLLARVGGRLVSPKDGMPEDIPLVWEGATLALV
                     RLEESTGGLDRVLEEVAAELGGPLVELSRVDKQRAVRLLEERGAFEFRRSAETVAAALG
                     VTRFTVYNYLHRTRS"
     misc_feature    complement(17959..17974)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.67"
                     /tool="antismash"
     misc_feature    complement(18012..18023)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            18048..18533
                     /gene="uraD"
                     /locus_tag="D5S18_RS14545"
                     /old_locus_tag="D5S18_14545"
     CDS             18048..18533
                     /EC_number="4.1.1.97"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraD"
                     /inference="COORDINATES: protein motif:HMM:NF010372.0"
                     /locus_tag="D5S18_RS14545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14545"
                     /product="2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline
                     decarboxylase"
                     /protein_id="WP_203236745.1"
                     /transl_table=11
                     /translation="MVTLAEFNSAAEEQLSPLLHSCCDAAAWVREMLAQRPYPDVNSAL
                     AAADTAARALTGPEVDAAAAAHPRLGEPVAGTDPHAEWARSEQSDVAGSAALAADNRAY
                     EHRFGRVFLISASGRSTEEIRTALRRRLANDDATEAAVVADELREIAVRRLREVLGG"
     gene            18530..18853
                     /gene="uraH"
                     /locus_tag="D5S18_RS14550"
                     /old_locus_tag="D5S18_14550"
     CDS             18530..18853
                     /EC_number="3.5.2.17"
                     /GO_function="GO:0033971 - hydroxyisourate hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006144 - purine nucleobase metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uraH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007295530.1"
                     /locus_tag="D5S18_RS14550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14550"
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_120041214.1"
                     /transl_table=11
                     /translation="MSAVTTHVLDAGLGRPGAGVPVRLERADGRVLAANVTDADGRIAE
                     LGPSHLEPGAYRLVFDIETYSAATGQTHFFPEIALTFTVSDGAHYHVPLLLSPFAYSTY
                     RGS"
     gene            18861..19766
                     /gene="pucL"
                     /locus_tag="D5S18_RS14555"
                     /old_locus_tag="D5S18_14555"
     CDS             18861..19766
                     /EC_number="1.7.3.3"
                     /GO_function="GO:0004846 - urate oxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pucL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007319197.1"
                     /locus_tag="D5S18_RS14555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14555"
                     /product="factor-independent urate hydroxylase"
                     /protein_id="WP_120041216.1"
                     /transl_table=11
                     /translation="MGITLGPNQYGKAESRIVRIYRDSPRHRLRDLSVSTALRGRFADA
                     HITGDQRDVLPTDSQKNTVFAFAKAKGVASIEEFGIVLADHFIDRCPGADGARIEIEEY
                     PWERIEVDGVGHDHAFVRSGHGVRTTVVNIDGAGAARRAHVISGVRDLILLKSTGSEFR
                     GFFVDEYTTLAPTTDRIMATSLVARWRYDHLAVDWDRAHEAIRSTLLNRFATEYSLALQ
                     QTLYDMGRAVLQQHPEVAEIRFSAPNRHHFPVDLRPFGFENPGEVFFAADRPYGLIEAS
                     VLREDASDAGNAWLGTPGFC"
     gene            19900..21276
                     /gene="allB"
                     /locus_tag="D5S18_RS14560"
                     /old_locus_tag="D5S18_14560"
     CDS             19900..21276
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005571373.1"
                     /locus_tag="D5S18_RS14560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14560"
                     /product="allantoinase AllB"
                     /protein_id="WP_203236746.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.4e-27, bitscore:
                     89.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDRGHRGGDPGTGAMELVIRAERIVGATGEFAGVIGVREGRIAA
                     IEPVGSPLSADEMLDLAADEVLMPGVVDTHVHINDPGRAGWEGFASATRAAAAGGVTTL
                     IDMPLNSIPPTCDPDALRRKRDAARDRVFVDVGFWGGAIPDNAEQLRPLHEAGVFGLKC
                     FLLDSGVPEFPPLDTAQVERALREIREFDGLLLVHAEDAQAIARAPEAEGDRYADFLRS
                     RPRGAENLAIARVIELARWTAGRVHILHVSSADALPMLASARADGVRVTAETCPHYLTF
                     AAEQIPDGATPFKCCPPIREASNRELLWEGLREGGIEMIVSDHSPATADLKCLDTGDFG
                     RAWGGISSLQLGLSAVWTEARRRGFTLVDVARWMCRAPADHVGLVHKGRIEIGCDADFS
                     VFAPETLCVVDPTRLRHRNPVTPYAARPLSGVVRGTWLRGRRIDIDGEPRGRLLARGEP
                     "
     gene            21273..22409
                     /gene="alc"
                     /locus_tag="D5S18_RS14565"
                     /old_locus_tag="D5S18_14565"
     CDS             21273..22409
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009475264.1"
                     /locus_tag="D5S18_RS14565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_14565"
                     /product="allantoicase"
                     /protein_id="WP_120041218.1"
                     /transl_table=11
                     /translation="MITPEFLRLPDLASRALTGSVVDASDEFFAERENLIEPARAVHDS
                     SEFGHKGKIYDGWETRRRREPGHDHAIVRLGAPGRVHGVVIDTAWFKGNYPPHISVEAT
                     GVEGYPTPTELAETEWITLVPKSEIAGDSANYFAVADARRYTHVRLSIYPDGGVARFRV
                     HGTPLPDPRFLSGTIDLAALEAGADIVEVSDSFFGDPRNLLLPGRAGHMGEGWENARRR
                     AHGNDHVVIRLAAAGIPRRVEIDTSYFRGNAPGAASLSGGDGATWAELLPKTRLQPDTR
                     HHFALTSATPITHLRLDVYPDGGVARLRLPGEIDPKALADAAIAWLAALPAHHAGAVLT
                     AVCGPTEAETLLATGSLRPEAIPATAITALLGMRSDFG"
     gene            complement(22447..22626)
                     /locus_tag="D5S18_RS34870"
     CDS             complement(22447..22626)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS34870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158607872.1"
                     /transl_table=11
                     /translation="MPLRSEGRGEGLPPGPIGDGNGLPFRPSGGGRQPEALICATGAGS
                     GVAVAEPPRAGQRR"
ORIGIN
        1 aggccgaggc attccaggca gtcgagaagt ttgtacaggc gcatgggaac gaggccgaag
       61 cgctcgctca gttcgccgag ggtggtgggt tcggagtcga ctgcgtcgag gatgccgaga
      121 tcgagcgccg tgccaacggc atcgacggcc ttctcgccgt ggaagagcag gctgagtaac
      181 gccctggagg gcaggttcat tcggagagtt cctgtctcgc ggcgatgagc gcgtccatga
      241 aggcatccac ctcatcgaga gtgttgtaga tgtgtggggc gattcgcagg ccatctcgcc
      301 agctgcagac catttcgcgg tcggcgagcc gctgtttgac cacgcggtcg ccggggaagg
      361 cgagagtgac tatgccgccc cgacattcgt gctgtcgggg tgtgcggatc gggatacccg
      421 ccgcgtcggc gcgcgcgatg acgcgatcgg tgcagcgcag cgagtgatcc cggatcgcct
      481 cggcgccgaa ggtcgcgagc aggtcgagcc cgagcctgga gatcatggcg gtcaatggaa
      541 taggtgtgcc gcccgcgagt cgcctggcgc tgtcggccca gtcctcggtg ggacggaaag
      601 tgagcgggtc ggcaccggcg aaccaaccgg tggcggcggg acgcagggtc ggtattaggt
      661 cggggcggat gtacaggaag gcggtgtgcg cgccgcacag ccacttgtgt gagccgccga
      721 ggaggtagtc gacgcctagc gtgcccatat tcagcggtac ggttccgacg gtttggaacg
      781 cgtccacaat cacctcggcg cccacggcat gggcggcggc cactatgcgg ttcaggtcca
      841 gcagtccacc ggtggtgtag ctgccgtgcg cgacgcagac gagcttggtg cgcgcactga
      901 gcgccgcgag caccgccccg gtgtcgaaat cggcgatctc cacctgtgcg ccgtagcggg
      961 cgaaaccccg ccacaggaaa gggacagtag ggaactcgcg attggtgatg agcacttcgc
     1021 ggcgcggacc gtcgaagtcg aaacaggtgg cgagcctgcc gagcagcgtg gtcagattcg
     1081 cctcggtcac gatcgaatcc actggtgcgc cgaggaattc ggcgagagcg cgcagatagc
     1141 cgtcgagttc gtcgagccaa cccgaccagg catcgtcgcg ccagtcccgc agcgtatccc
     1201 agtagcggcg cagtacctgc tcgacatcgc gcgggatcgc accggtggaa ttgctgttga
     1261 gatagatacc ggaccgcagc accgggaact ccgcgcggag ggcggcgatt cggtcgttca
     1321 tcgcgaactc cgctcggcgc ccggcgcgta cccgcccccg gcatgccagc tcgcggtgag
     1381 ctcggttctg gactgccaca gcttgcggaa caggggtttg gtcatccgac ccgtaagtac
     1441 cgcggtcggc acaccgtcga gggcgttgac cccgcgcccg accccgatag tcctgcgcac
     1501 caacatgaaa tgaccgacca gccacatctg gaagcgctca tccagatcga ccagcaattc
     1561 gcagacccgc ttgagatgct gcggtggtgt cgcgccgtac acgtcggtga gcgcgatccc
     1621 ctcgcgctcg agcagccgat ccaatgccgc cgccacatat tccgccgccg tgagcaccgc
     1681 attgaaaccg ggcgactcct gcccgctgcc ctggccgaga ctgcgccgaa tcacctggta
     1741 ggtgtccggc gtcatggtct cgagcacccg cagctcctcg gcgagacaat cggcgatgcg
     1801 cgccacccgt gccaaccgcg ccgaaacctc ccacagcgca tgggaatcca attctccgac
     1861 cacgtcgacc agttcgtggg ccaaaagctt cagccaaatc tcctgtgcct gatgcacgat
     1921 ctggaacatc agctcatcgg aatcggtgag atcctcgtgc gccgtctgca atgccaacag
     1981 atccgacgtc cgcaaataca tctcgtaatc ggtgaccccg gccccgaccc aacttttgag
     2041 cacgggattg aaaatcggct tgccgatcgc cgtccgcaac cgcgtggcct cggtctcgtc
     2101 ccccatcgcc gcgtccttct ctcggaatac tcattggaat cgacagtttc acgatgacac
     2161 aggtggggcg tgcgagccct gtgccggttc gctcaccgga gcgcggtgcg gactcgacgg
     2221 tatgtgggct gcccgtgctc ctgccggtcg aatgcgatgc cgcagaacat cattcgccta
     2281 cgcggccgtc cgtgcctcgg ctaccttggt acaaggctca atccgttgcg gagattgatc
     2341 gggggttcga gatgtcggat atcggtaggg aacgtcgtcg gcggtgggcc gaggagcaac
     2401 tcgcgggttt gccgcatctc tccgcgccac agcgcagatt cctttccgtt ccgctgatgg
     2461 agagtgggtg gcaactgctg gtgcaccgct ccggagtgct gcgcggtcgg cctgtggctt
     2521 tcgcggtcgg tcgaaccggg gtctatgccc tcgtcttcac cgacgacatc ccggaaatcg
     2581 agcagttgcg tcgaattcgc cgatacgccg aggagacctt cggtgggctc ctgctcggcc
     2641 gccgccagta tgtgccgcac atgctcgagg tgatgttgct gatgggcaag gcggttcgga
     2701 cacaagcgca cgatccgtat ctcgcggtgg acgagacgac gatgcgatcg accttgctga
     2761 acggcgagca gaagctcacg ccgcagcgcg cgcgggactg tgtggcggca gtgctcgcgc
     2821 gagatcagca gtattcgtgg atatcgaccg cgaatgcgcc cagggccgaa ataacctcgg
     2881 cggatggact tttcggtgtc gaggagttgc gcgaggacga gcggacccgg gtgctgcggc
     2941 gcccgttcga ggagtggatg accttcctcg atccggacca actcggttat gtctccgtaa
     3001 atttcaacgg tccggctcga ttcagcggcc cggcgggcac gggcaagacc gtggtggcgc
     3061 tgcaccgaat ggcgcggttc gccaagaaca atcccggaaa actgttgttc acgagtttcg
     3121 tcaaaacctt gcccgcacat catcagtcgg gattcgcgcg catcgccgag cggcacgcgg
     3181 atcgcgcgga attcatcggc ctgcatgcct gggcgatgcg gttcctgaac cgccgccggg
     3241 tgaagttcga tttggcggaa gatggtcagg tcgtgactgc gttcgcccgt gcttggagcg
     3301 caggtcgcca tgagctgagc cgaatcccgg ataccgatcg aaattattgg gaggacgagg
     3361 tcaagcgggt gatcaagggt cgaggcatcg actcgttcga tgactacgag aagatcagta
     3421 ggcccggtcg cgatggggtc aggctctccg gcccgcgcaa gaagctggtt tgggacaact
     3481 tctacctgcc gtatcaggcc cgcctcgccg agaagaacct cgatgacttc aacgatattg
     3541 tgcgcaaggc gatcgcggaa ttgcgcattc gtccgctcgt cggtgccgag aagttcggca
     3601 tggttgtggt ggacgaggtg caggatttca cgctccaaga gctccggttg gttctcgaga
     3661 tcgcgggtgg cggctccgag gcacagttgc tcctggtggg cgatgggcag cagcaggtgt
     3721 attccggcgg ctggaagctg tccgacgcgg gaatcccgct cgcggggcgt ggtcgagtgt
     3781 tgcgcaccaa cttccgcaat cgcgccgcga ttctgcgcta cgcgaagcgg atcgaagccg
     3841 ccgatacggt ggacgacctg gacggtggca ccggattcgt acttcgtgac agcgacgggg
     3901 tgctcgacgg tggcacggtg atcgaaaagt ccattccccg tgccgatctg gacaccgaac
     3961 tggtccgcgc gatcaccgaa tcggggatga ccgcctcgaa ttgcgcggta ctggtcaaca
     4021 ccaaccacga ggccgcccac taccagcagg tcctcgagtc ggccgggttg tccgcactgc
     4081 ttttggagca ctacaacggc actcagcaca gcgcgataga ggtagggacg gtttatcgcg
     4141 cgaagggcct cgacttcgcc gcagtcttcc gaatcgcgga accaattccg cgaggcaaca
     4201 acccagccga ccgcgaccgg gccgaactac tcgcccgcca acaccttgtc gctgtcacca
     4261 gagcgcggga ctacctgtgg gtcggactgg tcggagacta ggaccccttg ccgatccgcc
     4321 gccaatcggg caagcgcctc ctcggtgaat accgaaagcc cgaggtccgg gttgtatccg
     4381 tgaatttcct tcacatcgag ctcggccagg aaatacagga tctccgtcga gatcacctgc
     4441 cccggaacca gaaccgggaa tccgggcggg taggggacga cgaaggtggt ggataccagc
     4501 gtcctacctt tggcgatctg tcgcccggca tcgccgagca ggatatgttc ccgatcggat
     4561 tcggtgtacc cggcatagaa ggccgcgcgc atatcgccga acgagctgtc gccatcgggt
     4621 cggaatgcgc ggtcgaacgc gctgaagtcg gggagtgcgg gcagatcctc ggtgatctcc
     4681 cggactcggc gttcgtgcag cgcccgatca gcccggcccg ccgcgtcccg actgcggtcg
     4741 agatcgtcgg cgatccggcg cagcacatcg agcagatagt gcacgctcga ccaggtgacg
     4801 ccgatggtga agatcagtag cacgctattg atcgaggtct tgttgatctg gataccgaac
     4861 cggtccatca gtactttctc gcggaattcg aatccgttca taccggtctt gccgatgaac
     4921 agggtgaccc gcgtcgggtc gagcacgaac tgatccgacc gccacgcctc attccactcg
     4981 gccagtccgc cctgcctgac ctcccggtac gagctgaccg cggaggggcg aaactcctgg
     5041 gacaccaagt cgtcctcgtc gagaatgcgg aaccatttgc cgatcagccg gtccttgcgg
     5101 acccggtgcc ggaagaccag cgccatatcg tagacattgc gaaccagcag gaagccctcg
     5161 atatcgactt ggcggcgtgc cagatccaag gacgccagca gctgttgatt gggcgaggtc
     5221 gaggtgtggg tcaggaacgc ctcaccgaaa gactccctgg tcagggcttt gaaatcctgg
     5281 tcgcggacat ggatcatcga cgcctgccgc agcgcggaca gcgatttgtg ggtggaatgc
     5341 gtggctacac gcggattcgc gcccgttccg gatcgggcag cagccagtgg ttgtgccatt
     5401 cggcgcggtc gattccctgc atcgacgcgc gccaggtgcg gtagtcctcg gcgtattcgg
     5461 gcgaggacag catcgcctcg agctgttcgg cggcgaccat cgcggtccgc tgccgcgccc
     5521 acggcaccgc ggtggcgaag gcgtaccacg cctcgtccca caggaagcag atatccggtt
     5581 tgatcgccag cacctcctcc atcacccgtc gcgggttgta gacgatgccg tcaaaggtgc
     5641 agttggtgag cagcagcatg cgcacccgat ccagttgacc ggccgcctcg aggtccagca
     5701 gcacgcgttt gatggtgtgc agcgggacgg ctccgtacat ggcgaacggc tcgagcgggt
     5761 aggcgtccag gtacagcggg tacgccccgg ccagcaccag gccgtagtga tgggatttgt
     5821 ggcagttgcg gtcgatcagc acgatatcgc cggggcgggt cagcgcctgc acgacgatct
     5881 tgttcgcggt cgaggtccca ttggtgacga aatatgtctg attggcccgc cacgtccgcg
     5941 cggccttgtc catggctgtt cggatggtgc cgtgtgggtc gagcagcgaa tccaacccgc
     6001 cggaggtgga cgacgtctcg gccatgaaga tattgcggcc gtagaactcg cccatgtcct
     6061 gcaacgactt cgaattgaag atgctggcgc cgcgcgcgac cggcagcgcg tggaattgac
     6121 cgaccggcgc ggccgcgtag gcgcgcagcg cgtcgaagaa cggtgtggcg aaccggagtc
     6181 ggaaaccggc cagcacggtg ctgtacaggt cggtgacatc gttgagtcga tagaaggtgc
     6241 ggtcgtagac gttcggctcg tcctcgggtt cggcggcgat cgactcgtcg gtgagcaggt
     6301 ataggtcgat atggggccgc agttccctga tccactcgcc gcactccacc cagttggcgg
     6361 tgcgctctgt cacggcgacg ccggtattga cgccgagcag cgtggtcatc agcgggaccc
     6421 ggtcgcgcga gcgcagcggt aggtcgtgcc ggatgatcgc ggcctggacc tcgccgttca
     6481 atgcgacggc ggcgatcgcg tcctcgatgc tcgacaccac gagcagttcg aagcgcacat
     6541 cgtcggacgg atcgcgcagc gcccgcagac gctcggcgag gctgtcgggt gattcgggtg
     6601 gggaatcgtc gccgaggacc acggtgaagt actgccgctg ctcggtccgg gccaccagct
     6661 cctgatcggc caggggggcg gagttgttga aggcggtcgc gccgtcgccg tactcggaga
     6721 gcagacgcac ggccagcgac acctcctcgg tgagtcgcgc cgtggccaga tcggcgaggt
     6781 agccgcggaa ggctgccagt cgcgccgcgc cggggtagag ccagtaccgc tcgtacgcgc
     6841 cgaggcggtc gagcaggcgc cgtaccaccg cggtctcgtg ggcggtgtcg agtccggccc
     6901 ggttgacctc ggcgagcctg cggcacgcgt cgtcgagcag attccaggtg tcgatgcgcg
     6961 agtacgacgg gttcgctacc gccgccagcg cggaaaccga gagccctttc gggcgtttgc
     7021 catctcgatg catgtcctcg cgcccctagg tggtgggcgg agtgaactgc cgaatgacag
     7081 ctcacctgga acattcgtcg tcgaatattc tgccgcgccg aggatcgaac gcgtagcgga
     7141 ttcgagccgg gcggtcggtc cggttcgcgc ggtgcagcgg gtccccgcag cgggtttcgc
     7201 ctgtatcgaa tccatgacga tcgtcgctga tacattcgat ccgtgacgat ttctgatgag
     7261 gtgcaccacg tccaggacga caggaaggtc accctgcgcc gggtcaccgg gcggacggtg
     7321 ggcgcgatct gcgacctgtc cgagacgctc accgaagagc agcgggatat ggtcgccgac
     7381 aacgcgatat ccattgccga ggcgcacttc tcggagaacg cctggttccg cgccatctat
     7441 gtcggcgaat ccccggccgg attcgtcatg ctgcacaccg gctacgacta cgacgaaggt
     7501 ttcgactgcc acggcgtgtt tctctggcgc atgatggtgg ccgggccgtt ccagagcaaa
     7561 ggcgtgggcc gcaaggccat cgacttgatc gtcgcggatc tgaaagcccg tggcatcaac
     7621 gagctttaca cctcctacgg gcaaggcgct gccggccccg agccgttcta caagggactc
     7681 ggttttctac ccacgggtga tttttacggc gaaggagagc accgggaaat cggtgtcgtc
     7741 cttcgctggt agcggcgcga attcgcctgg agccgagggg atcagggtgc gtcgatggcg
     7801 gggtggcgca gtcgcccggt gttggcggcg atgaggtcgg aaagggcctg ttccggatcg
     7861 gtgcggcggg tgcggcggtg catgaggacg aattcgaggt cgccgagttc gggcagggcc
     7921 gggtcgggga ggggggaaag tccttcgggg agtacggatt cggcgtgcac gacgacaccg
     7981 agtccggcaa gggctgccgc gcgcaggccg agcaggctgt cgcttacgca ggcgatgcgc
     8041 caggtgcggc ccgcctgttc gagggcggcg agggcgcggc ggcgggtgag gctcggcgcg
     8101 gggtaggtga cgagggggac cggatcctcg agcggcggcg tcgcgggtcg gcccgcccag
     8161 gtcagcttgt cgcgccagag cagttcaccg tggcgttcgc cggggaggcg cttgccgaag
     8221 acgaggtcga gttccccggc cgccatgcgg gttttgagat gttcgctgat cccgacggtg
     8281 agttcgaggt cgacgccggg atgggtgcgc tggaattcca tcaggatatc gggcagttcc
     8341 agggccatca catcgtcgga ggcgccgagg cggatcaggc cggtgagtgt cgaaccggag
     8401 aagtacgcgg cggcgcgggc ttgggcgtcg aggatggcgc gggcgaaacc gaccatggcc
     8461 gcgccgtcgg cggtgagtgc gagattgcgg gtgtcgcggc ggatcagttc gcggcccgtc
     8521 gcctgctcga gccgtgcgat atgaccgctg acggtggact gccgcaggcc gagcagccgc
     8581 ccggcggcgg tgaagccgcc cgcgcgctcg acggcgagga aggtgcgcag cagttcggga
     8641 tcgaacacct cgcgaaccta tcatgattcg cgatcagaga tatcgggtcg aacgtctttc
     8701 gcgatgatgg ccagggctcc tagcgttcga aaggtgaagc tcttagccaa attgcacatc
     8761 gacggtttca tgctgggcat cctcgccacg gtggcggtcg ccgccctgct gcccgcgcgc
     8821 ggcacggcgg ccgatgccct cgattgggcc accaagatcg ccatcgccgt cctgttcttc
     8881 ctctatggcg cgcgcctggc gccccgcgag gcgctggccg gactgcgaca ctggcggttg
     8941 catgcgagcg tgctcggcac caccttcgtc ctgttcccgc tgctcggcct gctactgcgc
     9001 ccgctatcgc cctcgctgct gcccgccgat ctatacaccg gggtgctgtt cctgtgtctg
     9061 gtcccctcaa cggtgcagtc gtccatcgcc ttcacctcga tggcccgagg gaatgtggcg
     9121 ggcgcggtgg tgggggcctc attgtcgaat ctggtcgggg tgttcgtgac cccgctgctg
     9181 gtggtgttgc tcatgaaaac gacgggggag gtgcgggttc cactcggctc ggtggcgctg
     9241 atcgtggtgc agttgctggt gccgttcctg gcggggcagg tgctgcgccc ccggctgacc
     9301 tggctgctgc ggcacgccgc ggtggtcggg tcggtggatc ggggctcggt ctatcttgtc
     9361 gtctacgcgg cattcagcgc ggggatgacg gagggtatct ggaagtcgct ctcgcccacg
     9421 acattgttga tcacggcggt ggtgtgcgcc tgcctgctcg ccttcgtgct gtgcgcgacg
     9481 acgctgagcg cccggctgtt cggcttcgct cgcgccgacc gcatcgtggt caccttctgc
     9541 ggctccaaga agagtctggc gacgggactg cccatggcct cggtcctgtt cgccggtcat
     9601 cccatcggaa tgatcgtgct gccgctcatg ctgtttcatc agatccagtt gttcacctgc
     9661 gccgttctcg cgcagcgcta tgccaggcac gtcgaggtcg acccattggg aaatgcgccg
     9721 tccgagagcg gcacggtgga cgaactcgga caatccggcg cgatgtctcg gatgggtgtg
     9781 tcggtcgatc gatcctgatt cgttaccgcg caacggtatt cgtatcggtt tcggcattcg
     9841 ggccacggcg ggcggttccg gtcctatcat tcgtgttgct ggaatgtatc tgccgcactt
     9901 gtcaattcgc tcgagtgttt gtcccaaggc agcttcgctg agcctgctca gtcgtatccg
     9961 tcgccgacca gcgccggcca tcccaggtga ggaccgcagg atgacaattg aaccgttcca
    10021 gttgcccgag ttctacatgt cctatcccgc tcggctcaat ccccatgtgg cggcggcccg
    10081 cgcgcataca cgggagtggg cgcgcgagat gggcttcttc gaggatcagc agggcgtcca
    10141 catctggagc gaacaggatc tggagcgaca cgactacgga ctgctgtgcg cctacaccca
    10201 tcccgattgc gatgagcggg aactgaatct cattaccgac tggtacacct gggtgttcta
    10261 cttcgacgac cacttcctgg agctctacaa gcgcacccgc gacaccgcag gcgcgaagca
    10321 atacctggac cggctgcggg acttcacacc tgtcggcggc ggcgcaccgc cggagccgac
    10381 caatccggtg gaacgcggcc tggccgacct gtggacgcgg accgcgcccg ccatgtcacc
    10441 cgcttggcag cggcgcttcg cggcgagcaa ctgggcactg ctggtcgaat cccgctggga
    10501 actggccaat atcgcggcgg gtcggatcgc caatccgatc gagtacttcg agatgcgccg
    10561 caaggtgggc ggcgcgccct ggtcggccga tctggtggaa catgccgcgg gcgccgaact
    10621 gccgccgcgc ctggtggaca gcagacccct gcgggtcctg cgcgacacct tcgccgatgc
    10681 cgtccacctg cgcaacgaca tcttctccta tgagcgcgag gtgcggcagg agggcgagaa
    10741 cgccaacgcg atcctggtgg tggagaacta tttcggctat cccacccagc gtgcggcgac
    10801 ggcggtcaac gatatggtca cctcgcgcat gcagcagttc gagcacacgg cactcaccga
    10861 ggtgcccgcc ctgctcatcg aatccgccgc gacgccgcag gagcagtggg cggtggccgc
    10921 ctacgtgaag ggtttgcagg actggcagtc cggcgggcac gagtggcata tgcgatcgag
    10981 ccgctatatg aacgcccacg ccaacaccga aagggtcggg ctcccgttcc tcagtgccac
    11041 tatcggtttg accaaaccca gcctcgacag tctcggcccg aagcgggtca agcagttccc
    11101 gccttcgctg gtcgagcacg cgggttcctc tgggacacag ggtctttcgc tgccgttcga
    11161 ggtgcggatc aatccgctgc tcgacgctgc ccgtgagcac acggtgcgct gggcacagga
    11221 gatcggcctg ttcgaaccgg tccccggcgc cgcgcgtccg ctgtggcgcg agcgggatct
    11281 gcgcgatttc gacttcgctt tggccaccgc gggtatggga ccggatgccg ggcaggcgga
    11341 tctggatacc gctacggatt ggctcacctg gggcacctac atcgatgact actacctcga
    11401 ggtcttcgga cacggtcgcg atgtggcggg cgcgaaggcg cagggcgcgc ggttgctgga
    11461 attcgtgccg gtggatctcg gcgcggcacc gatacccctc acctgcatgg aacgcggact
    11521 cgcggagctg tggccgcgca ccacggctgc gatgggaacc gctcagcgcg aacgcttccg
    11581 gcgggcattg gcccagttct tcgccggact gacctgggag acaagcaatt tcgccctgaa
    11641 ccggatcccc gatccgatag atcagatcga gatgcgccgc cttgctttcg gcggggatct
    11701 gacgatgggg ttggcgcggc tatcctacga cggtggggtg tccgacgagg tggaacaatc
    11761 ccggaccgtg cgcgatatga acaccatcgc ttgcgatgtg gccatgttga ccaactgcct
    11821 gttctcgtat cagaaggaga tccgattcga gggcgatccg cacaacaccg tgcgggtgct
    11881 gcgcaacttc ttcgactgcg agcacgccga ggccgaacgg cttgtcggca tactgatctc
    11941 gacccgcgtc gaacagttcc agcgactggt cgagcacgaa ttgcccgcgc tctacgcgga
    12001 atacgagctc gatcggcggg cgcggcagga cttgacacgc cgcgctgcga acctgcgcga
    12061 ctatatggca gggatattga actggcatca gggttgccgc cgctacaccg aaccggaact
    12121 gctgcggcgc ttccgccccg agctgttcgg ttccgggctg ggtgcgcgca cccccggcct
    12181 cggcgccgcc cgactcgacg cactcaccgc tcggatgggc gagcccttcc ggtcaccgac
    12241 aggagcgccc tcatgaccgc ggtcgtatcc gtctcgccga cccagccgcc caccgaaatc
    12301 ctcgctcgaa caagaaaact cgtcgaaccg atgctgcgcg aggccattgc cgcgctgccg
    12361 gatccgctgc gccgcatggc cggataccat ttcggctggt gggatgtgcg cggcaatccg
    12421 gcccccggcg aatcgggcaa gatgctgcgc cccgcgctca ccgtcagcgc ctgcctggcc
    12481 tgcggcgggg tgccggagga cgcggtgccc gcggcggtcg ccgtcgaact catccacaat
    12541 ttcaccctga tccacgacga tgtcatggac ggcgatacgc tccggcacgc ccgcccaacc
    12601 gtgtggacga tctggggcat ccccgacgcg gtgctgctgg gcgatgccct gcacgccgtc
    12661 gccgctgagc tgctggtgcg cgcgatgccg cacggcgtgg gcgcgcaggc gctgcaacgg
    12721 ctggagtcgg cggtgatcga gctgtgtcgc gggcagcatg aggactgcca cggccaaagc
    12781 ggtagcggcg cgacaatcgc cgactgcgaa cgaatggaga tgggaaagac gggcgcgctc
    12841 atgggctgtg cgtgcgccct cggcgcgttg gccgccggtg ccgcgcccgc caccgtcgcg
    12901 gccttggatc ggtgcggtcg ggaattgggt ctggccttcc agttcaccga tgatctgatc
    12961 ggaatctggg gcgatccgct ggtcagcggc aagccgacca gcgatctggc ccggcgcaag
    13021 cgatccatgc cggtcgtggc ggcgctctgc tcgcagaccg cgcaggcggc ggaactggcg
    13081 cggatctacg ggggtcgaga tccgatgtcg cccaccgaca tcgcccgtgc cgccgaattg
    13141 atcgaagaag cgggtgggcg gaattggacg cagcgccaag cggatcggca tatccaggcc
    13201 gcgctgtgcg aactgcccga cgcgcgcacc gccgccgacc tgatcgcgct ggcctgcctg
    13261 gtgacgcatc gaaatcgatg atcccttcga gcgatccgcc tactactcgg cgttgacgcg
    13321 gatcactcgt cgggatgacg gaaagatcgg cattcggctg gatctgcgcg cgtcgcgaat
    13381 tcgggtacgg tcctgcacat gtccgctgtc acgtcggaat ccgacaccgt gcgcgaggaa
    13441 tcgccgtccg aaaatccgtg gacggccgcg cagaaggtcg ggttccgact tttcttcgcg
    13501 ctcggctccg ggctgctggt ctatgtgctc ttcaccaata tggccaccat cagcgtcgtg
    13561 ctcctgccgc tgaaagtgtt gctggccaag atcggtgggt atttggtcgg cgatggatcg
    13621 gtcacctccc agctgggcag gggcgatggc ctgggcgact ggtacggcat gttcgccgtg
    13681 gtcgtgctgg cgatcatcgc cgccgtcgtg tggacgcttc tcgacaagcg gcgggacaat
    13741 taccgcaagc tcggtcgggc gctgttcgag gtgacgcgtt tcgccgtcgc ggtccaactc
    13801 atcaactatg ggttgggcaa ggcgataccc atccaaatgg gattcatgaa ccagcccatc
    13861 tatcggctcg tgccggtcgg ggatctctcg ctcatggata cgctctgggg attcatgggc
    13921 gcctccaacg cgtacacgat cgttgccgga ttggtggaat tgagtgccgg tctgatgctg
    13981 ctgtggcggc gtacctggct gctcggatcc ctggtcggcg tggtggcgat ggcgcaggtc
    14041 ttcctgctga acctcaccta cgacgtcccg gtgaaaatgg tggccgggac gctgctggcc
    14101 gcctcgatct gtttgagcgc gccattctgg acctcgcttg cccgcgtgat attgaatacc
    14161 ggtccggtgc gcccgcgcga gttgtgggac gcacccggtg gaccgcgaac tcgaaaatgg
    14221 gcgctgcgta tcgggtattt ctacgtagtc gtgcagacag cgctcatggg tgtgctattc
    14281 ggtacagcgc tgcacgatat gcacacggtg cgctcgggat tggacggggt gtggcaggcc
    14341 acgtccgtcc gcatcgacgg atcacccgcg cggctgaaca ggggagcccc cgaaccgtgg
    14401 gcgaatgtgg cgatcaacga ccgccccggc gattacaccg cattcgccag tcaggacccc
    14461 ttcgggcaca ccgaccggtg ggcgctgaaa atcacggaca ccacactgga gatccgcaaa
    14521 agactctccg atcggccgtt ggaaatccga taccgctggg acgacgagca caccctggtg
    14581 ctcaccggaa ccctggacgg acacgagttc gagggcaaat accaccgccg cgccatgaag
    14641 agcagcgaat ccggattccg ctgggtgcag cccgatctcg accccgacgt gccgaagttc
    14701 tgaggctctc cgggtcggtt tagtccggca taccgagttc gatccagtag cggcgggccg
    14761 gacctatgtc ggtttgccga ataccttcca gcacaccgcc attgcgttcg atcgtgcgcg
    14821 cggaggcgat attgtcgacc gcgcagacca cgagcacccg cggcaggccc gccgcgcgcg
    14881 cctcgtccag catgcgagcc aacgcccagg tcgccagttt gcggcggcgg gccgacgggc
    14941 gaatcccgta cccgatatgc cccagatcgc tgtaatcgtg ccgcagcacg ataccgccga
    15001 gcacctgccc gtcctcgacg atccagcggt aggtgctgta ctcgccgtca gcgcggccgt
    15061 gaccggattg attgttcatc cgtgccaccc aggccgcgaa accctcctcg gtatccacct
    15121 tttcgtacca gagcagcccg aatccgtcct cgtgactgcc cggcccccat tcctcgtggg
    15181 ccgccagcca ggcggcgtgg agggcgacag tgggggcgat cagttcgggc atggcaagat
    15241 cctcgcatct ccggggcact cgacacgata tcgattgtgg aatcggctgc ggcactaaag
    15301 tactggtatg tccgctgagc ccggcggggt gctcgatccg cgatggctat ggcgcgtcca
    15361 cgcggtcgtc ttcgtccgga agtccgcgaa cttctcaccg agtcggtggc gcggaagaac
    15421 tcctatactc atcgtctccg gctccgccgc ctcgatcggc gaaccgccca ctgaaaccgg
    15481 ataggagcgt cctcgacgac catggccgcc attcgccacg agatcgtgat caatgccgcg
    15541 cccactcgga tctgggatgt gctcgccgat gtcggggcgg tgcacgagcg gttgctgccg
    15601 gggcgggtgg tcgataccag gatcgaggga tccgaacgat ttctgacctt tcccgatggg
    15661 catgtgatcg aaggggatgc ctttcgtgcc gcgctgccga gacagcgggt atcggagcga
    15721 tcctgcgtcg cgcgcagggc ttcccgcggt tcgtcgcctc ccccgtgacg acgcggggcc
    15781 acgccgttcg cgcagcgtcg caggcggatg cggtgggcgt cgcgcgcatc gccggtcgtg
    15841 tccgcgtcgg cgagcggcag gtgcccgatc gacggcaacc gctcagcttc atcggcgcgg
    15901 accggcacgg atggatacgt gcctgtcgca tgggatgtca tggttcgact gtcgcgcgaa
    15961 tccgggcatc ggtccaacgg atttgatcac tgggaacaat tgatacggtc gatactcgat
    16021 gcttcggcag ggcatcggtc ctttggcagg caatcggttc taccgttgtg cgcatgacgg
    16081 gggccgcgcg aagggtgaga cctcatgcag gacgtaggtg gcgacgcact cggtgacgag
    16141 ctggatcggc ggctttccgg atgggatcgg gagctggcgg agaagtatcc gggtgatcgc
    16201 ggggtgcgac agccggtgca caccgtctat gttccggggg accggttcgt cccggagacc
    16261 gcgcggctgt ggggcctgga ggcgctgcgg atgctgggca ggcacgatct gcccgatgtg
    16321 cccggcctcg acgcggccgc ggccgccgag attcgtcacc gcgtcgaggt gaagctcgcg
    16381 atcgagccga tcgaggatct gcggatcgat ttcgaggacg gttacgggcg acgacccgat
    16441 gcggtcgagg acgccgacgt gcgtgccgcc gcacgagcgc tcgcgatctc ggtgcgcggg
    16501 aatgcgggcg cgccctttca tgggctgcgg ttcaagagct tcgaagcgtc gacccgtcgc
    16561 cgcggcttgc ggacactgcg tttgttcctc ggtacgctca ttgaaaacga cggtctcgca
    16621 ccgggattcg tggtgaccct gcccaaggtg accgcgccgg tccaggtcga ggcaatggcg
    16681 gcgacctgcg ccgccttgga gcgggaattc ggattgccct ccgggcgact gggattcgag
    16741 atccagatcg agacgccaca ggccatcacc ggcccggatg gcgcggccgc cgtcgctcgc
    16801 atgatccatg ccgccgcggg ccgctgcacc ggactgcact acggcaccta cgactattcc
    16861 gccgggctgg gcattgccgc cgcctatcag agcttggagc atccggcggc cgatcacgcc
    16921 aaggccgtca tgcaggtcgc cgccgccggg accggtgtgc acctgagcga cggctcgacc
    16981 aacgtcgtcc cggtcggcaa tcaggtgggt tcggcttgga cgctgcacgc gcggctggtg
    17041 cgccgctcgc tcgagcgcgg ctactaccag ggctgggatc tgcatccggc gcaattgccg
    17101 accaggtacc tggcgaccta cgcgttcttc cgggcgggtc tcccgcaggc ggtcgcgcgg
    17161 ctgcgcgcct acctgcacgg cggtgattcg ggcttcctcg acgaacccgc caccgccgcg
    17221 gcactggccg gattcgtccg gcgcggtctg gactgcggcg cgctggacgc tggcgacctg
    17281 gatggtctgg atccggcccg gttggccgag ttgtcccgcc gcgccccggc ggcccagtag
    17341 cctcggccta tgcggatgcg cgcggagttc accaccgaac cgttccacgg cgagggcgat
    17401 ccgccgccgc atgccaccgc cgcgctgcgg gtggccgaat ccctcggcct gacatgcgat
    17461 ttcgggccgt tggggacggc ggtggcgggg cgggacgcga tactgctgcc cgcgctcggc
    17521 gcgatattgg ccgccgcctt cgactccggt gccaccgggg tgacgctgcg ggtcgagcgg
    17581 gactaggggg tggacggttc gcatccggtg ctggtagcca tcgccccact gctcgcgagg
    17641 gtgggcggac ggctggtatc gccgaaagat ggtatgcccg aggatattcc gctggtgtgg
    17701 gagggtgcga cgctggcgtt ggtgcgcctg gaggagtcga cgggcggcct ggatcgggtg
    17761 ctcgaggagg tggccgcgga actcggcggt ccgctggtcg aactctcgcg ggtggacaaa
    17821 cagcgggcgg tccgcctgct cgaggagcgc ggggcgttcg aattccgcag atcggcggag
    17881 actgtggcgg ccgcgctcgg tgtcacccgc ttcaccgtct acaactacct gcatcgcacg
    17941 cggtcctgac accatccgtt caacaaaatg ttgacggtcg gcgcggcccg tgtcacgctg
    18001 aatcggaggg cgcgatcatt tccgtcagcc gagggaaggc gacccgcatg gtgaccctgg
    18061 ccgaattcaa ttccgctgcc gaagaacagc tttcgcccct acttcactcc tgctgcgatg
    18121 ccgcggcctg ggtccgcgag atgctggcgc aacgccccta tccggacgtg aacagcgctc
    18181 tcgccgccgc cgataccgcc gcccgcgcgc tgaccggtcc ggaggtcgat gcggcagcgg
    18241 cggcacatcc gcgcctgggc gaaccggtcg cggggacgga cccgcacgcc gaatgggcgc
    18301 ggtccgaaca gtcggacgtg gccggatccg ccgccctcgc ggcggacaac cgcgcctacg
    18361 agcaccgctt cggacgcgtc ttcctgatca gcgcgtccgg acggtccacc gaggaaatac
    18421 gcaccgccct gcggagacgc ctggccaatg acgacgcgac cgaagcggcg gtggtggccg
    18481 acgaattgcg cgagatcgcg gtccgcaggc tgcgggaggt gctgggcgga tgagcgccgt
    18541 gaccacccac gtcctggatg ccgggctcgg gcggcccggt gcgggtgtcc ccgttcggct
    18601 cgaacgtgcc gatggtcggg tgctcgccgc gaacgtcacc gatgccgatg ggcgcatcgc
    18661 cgaactcggt ccctcccacc tggaacccgg cgcttaccga ctcgtcttcg atatcgaaac
    18721 ctattccgcc gcaacgggac agacccactt cttccccgag atagcgctca ccttcacggt
    18781 gtcggacggc gcgcactacc acgtgccgct gcttttgagt ccgttcgcct actccaccta
    18841 tcgaggaagc tgagatcggc atgggcatca ccctgggacc caatcagtac ggcaaggccg
    18901 agagccgcat cgttcggatc taccgggact cgccccggca tcgcctgcgc gacctcagcg
    18961 tctccaccgc gctgcgcggc cgtttcgcgg atgcgcatat caccggcgac cagcgcgacg
    19021 tactgcccac cgacagccag aagaacaccg tcttcgcctt cgccaaggcc aagggcgtgg
    19081 cgagcatcga ggaattcggc atcgtcctgg cggatcactt catcgaccga tgtccgggcg
    19141 cggacggggc gcgcatcgag atcgaggagt acccgtggga gcggatcgag gtcgacggcg
    19201 tcgggcacga ccacgccttc gtccgctccg gacacggggt gcgcaccacc gtggtcaata
    19261 tcgacggcgc gggcgcggcg cggcgcgccc acgtgatctc cggcgtgcgg gacctgatcc
    19321 tgctcaaatc gaccggttcg gaattccgcg gcttcttcgt cgacgagtac accaccctgg
    19381 ccccgacgac cgaccggatc atggccacct cgctggtggc tcgctggcgc tacgaccacc
    19441 tcgccgtcga ctgggatcgc gcccacgagg cgatccggtc gaccctgctg aaccgattcg
    19501 ccacggagta ttcgctcgcg ctccagcaga ccctctacga catgggtcgg gcggtcctcc
    19561 aacagcatcc cgaggtggcc gagatccggt tctccgcacc caataggcat catttcccag
    19621 tggatctgcg ccctttcggg ttcgagaatc cgggcgaggt cttcttcgcc gccgaccgtc
    19681 cctacgggct gatcgaggcg agcgtgctgc gcgaggacgc ctccgacgcg ggcaacgcct
    19741 ggctcggcac acccggattc tgttgaacgc ctcgcaccct cgatcagggg gatatacccg
    19801 gcgacaccgg ccccgatggg gcgcgtcggg agtcggggcg cggctacgct gctgccacta
    19861 ctcctcgcgc ggactccgcg cgcgtattcg gaggtgcgca tgcacgatcg cggtcaccgc
    19921 ggcggcgacc ctggtaccgg cgcgatggag ttggtgatcc gggccgagcg aatcgtcggc
    19981 gcgacggggg agttcgcggg cgtcatcggc gtgcgcgaag gacggatcgc cgcgatcgag
    20041 ccggtcggct ccccgctatc cgccgacgag atgctcgacc ttgccgccga cgaggtgctc
    20101 atgcccggcg ttgtcgatac ccatgtgcac atcaacgatc ccggtcgcgc cgggtgggag
    20161 gggttcgcca gcgcgacgcg ggcggccgcg gcgggcgggg tgaccacgct catcgatatg
    20221 ccgctcaaca gcattccacc gacctgcgat ccggacgcgc tgcgccgcaa acgcgacgca
    20281 gcgcgggatc gcgtcttcgt ggacgtcgga ttctggggtg gtgcgatacc ggacaatgcc
    20341 gaacagttgc ggcccctgca cgaggcaggg gtattcggat tgaaatgctt cctgctcgat
    20401 tccggtgtcc cggaattccc gccgctggac accgcgcagg tggagcgcgc cctgcgggag
    20461 atccgcgaat tcgacggatt gctcctcgta cacgccgagg atgcccaagc catcgcgcgc
    20521 gcgccggagg ccgagggcga ccgatacgcg gatttcctgc gttcgcgccc gcggggcgcg
    20581 gagaatctcg ccatcgctcg cgtcatcgaa ctcgcccgat ggaccgcggg ccgggtgcac
    20641 atcctgcacg tctccagtgc cgacgcgctg ccgatgctgg cctcggcccg cgccgacggc
    20701 gtgcgcgtca ccgccgagac ctgtccgcac tatctcacgt tcgcggccga gcagattccc
    20761 gatggcgcga cgccgttcaa atgctgtcca ccgattcgcg aggcgagcaa tcgggaactg
    20821 ctgtgggaag ggttgcggga gggcgggatc gagatgatcg tctcggatca ctcgcccgcg
    20881 accgccgacc tgaaatgcct cgacaccggg gatttcggcc gcgcctgggg cggtatctcc
    20941 tcgctgcagc tcgggctgtc ggcggtgtgg accgaggcgc ggcggcgcgg attcaccctg
    21001 gtcgacgtgg cgcgctggat gtgtcgcgca cccgccgacc acgtcggcct ggtccacaag
    21061 ggccgcatcg aaataggttg cgacgccgac ttttccgtct tcgctccgga gacgctgtgt
    21121 gtggtggatc cgacccgact gcggcatcgc aatccagtga caccctatgc ggcgcgaccc
    21181 ctttccggcg tggtgcgcgg cacttggttg cggggcaggc gcatcgatat cgacggtgag
    21241 ccgcgcgggc ggctcctggc ccgaggagaa ccgtgatcac acccgaattc cttcgactac
    21301 ccgatctggc ctcgcgcgcg ctgacgggca gcgtggtcga tgccagcgac gaattcttcg
    21361 ccgagcgcga gaatctgatc gaacccgccc gcgccgtcca tgattcgagc gaattcggtc
    21421 acaaaggcaa gatctacgac ggctgggaga cccgtcgtcg ccgtgaaccc ggccacgacc
    21481 acgccattgt ccggctcggc gcaccggggc gggtgcacgg ggtggtgatc gacaccgcct
    21541 ggttcaaagg aaattatccg ccacatattt cggtcgaggc caccggcgtt gaaggctatc
    21601 cgacgccgac cgaattggcg gaaaccgagt ggatcacact ggtcccgaaa tccgagatcg
    21661 ccggggacag cgcgaactac ttcgccgtcg cggatgctcg ccgctacacg cacgtgcgac
    21721 tgtccatcta tcccgatggc ggtgtcgccc gcttccgagt gcacggcacg ccgctgccgg
    21781 atcccagatt tctcagcggc acaatagatc tcgccgcctt ggaagcaggt gcggacatag
    21841 tcgaggtctc cgacagtttc ttcggcgacc cgcgcaacct cctgctgccc ggtcgggccg
    21901 ggcatatggg cgaaggctgg gagaacgccc gccgccgcgc gcacggcaat gaccatgtcg
    21961 ttattcggct tgccgcggcg ggcatcccgc gtcgtgtcga gatcgacacc tcctatttcc
    22021 ggggcaatgc gcccggtgcg gcctcgctca gcggcggcga cggcgccacc tgggccgaat
    22081 tgctacccaa gacccgcctt cagcccgaca cccggcacca cttcgccctg acatccgcca
    22141 ccccgatcac ccatctccgt ttggatgtat acccggacgg cggagtcgcc cggctccggc
    22201 ttcccggtga gatcgatccg aaggccttgg cggacgccgc cattgcttgg ctggccgcgc
    22261 tccccgctca ccatgccgga gcagttctca ccgcggtctg cggcccaacc gaggccgaaa
    22321 cgctcctcgc cacgggttcg cttcgccccg aggccattcc ggctaccgcg atcaccgcct
    22381 tgctcggcat gcgaagcgac ttcgggtgat ggccgcagac ggcgactatc gccatttccg
    22441 ccgccatcac cggcgctgcc ctgctcgcgg gggttccgcg acggccacac cgctgcccgc
    22501 ccccgtggcg cagatcaacg cctccggctg cctgccgccg ccgctcggcc tgaacggcag
    22561 gccgttgccg tcgccgatcg gtcccggtgg caaaccctcg ccgcggccct cggatctcaa
    22621 cggcaagccc tgcccgcctc cgggtagata gtcagaaatc gctgtgtcgc aatgactttg
    22681 cgacacagcg ggcactcgag ccgctacctt cggccgcggc gccgcatcgc gtgatcgctt
    22741 cattccgaac accgccgaat gtgtcgagcc tactgggcgc taccggttgc cagatgaatt
    22801 ctgctgtgct ggttcatttt tcatctctca cctgcggaat cgcgcgcccc gcgcgccgcc
    22861 tcgtacggac gtacgaatcc gagtcgccaa gttcgtaggg acacacgaac cttctcgaga
    22921 cttcggtcac catcatagga cggccgggca ctgacgaagg agaagagatg acagtggctc
    22981 cacagcgatt aaccgactcg gtcgatacgg tgcccgaacg gctcaccgag atattccgcg
    23041 cggtgggcgc caccggatat gtgcacgcgc gcgaggtgga cggtcccggt gagatcggtc
    23101 tcggcgcaga ccacccggtg gtcctggcct cggtcttcaa gattccggtg gtgctgacct
    23161 tcgcgcgcca ggtcgaggcc ggtgaactgg acccgaccga gcgcaccacg atcaccgcgc
    23221 gcgaccgcat cggcggcatc ggcacggcgg gctgcgccga tgacgtcgag atgagctggc
    23281 g
//
