LOCUS       NZ_QZFU01000015        21395 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Nocardia panacis strain YIM PH 21724 NODE_17, whole genome shotgun
            sequence.
ACCESSION   NZ_QZFU01000015
VERSION     NZ_QZFU01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia panacis
  ORGANISM  Nocardia panacis
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 212700)
  AUTHORS   Miao,C.
  TITLE     YIM PH21274 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 212700)
  AUTHORS   Miao,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2018) Yunnan University, Yunnan Institute of
            Microbiology, 121, Kunming 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 29.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003598715.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 03:06:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,880
            CDSs (total)                      :: 6,804
            Genes (coding)                    :: 6,707
            CDSs (with protein)               :: 6,707
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 32 of 97
            Pseudo Genes (incomplete)         :: 82 of 97
            Pseudo Genes (internal stop)      :: 7 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:26:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 146265
            Orig. end                         :: 167660
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QZFU01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21395
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21395
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21395
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11395](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11395)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    320..333
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.12"
                     /tool="antismash"
     gene            complement(431..1039)
                     /locus_tag="D5S18_RS07935"
                     /old_locus_tag="D5S18_07935"
     CDS             complement(431..1039)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014351786.1"
                     /locus_tag="D5S18_RS07935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07935"
                     /product="hypothetical protein"
                     /protein_id="WP_239003615.1"
                     /transl_table=11
                     /translation="MNPRIVAVLFAGVLALSGCGQAIDDPVVGTDVAAPPTGLHWIDYQ
                     GIAIPIADQGPHTHSATAATGFADTPAGAALAAIVHTVRMSVAPDRTWSPIAASELAPG
                     PGKDAWIAARTLVSITKPAEKATAPTIIGYRVTAYLSKARAAVTAYTRYPDSSLAATHV
                     RVVWLGEDWLLDLPHPDSTQPTVETIREIPHDTVRLENR"
     gene            complement(1036..1305)
                     /locus_tag="D5S18_RS07940"
                     /old_locus_tag="D5S18_07940"
     CDS             complement(1036..1305)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS07940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_07940"
                     /product="hypothetical protein"
                     /protein_id="WP_147403892.1"
                     /transl_table=11
                     /translation="MPTKVFRIAASLPSEVTAPLAQLLSWLLWGCELILLGTIVACGAK
                     LWMERRQPEIQGRHTSTAIVVTLIAAGICSVALPIAATVVGNAS"
     gene            complement(1321..1599)
                     /locus_tag="D5S18_RS07945"
                     /old_locus_tag="D5S18_07945"
     CDS             complement(1321..1599)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982885.1"
                     /locus_tag="D5S18_RS07945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07945"
                     /product="hypothetical protein"
                     /protein_id="WP_120039181.1"
                     /transl_table=11
                     /translation="MHTIVLAGFEAIDQITADTPPGSEKLILLVRWLLWGVMLAGVAGI
                     IYAGGKFAWEKWNGGALESPKIVVAALIGGIVATSASALINTVVLAT"
     gene            complement(1599..2210)
                     /locus_tag="D5S18_RS07950"
                     /old_locus_tag="D5S18_07950"
     CDS             complement(1599..2210)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042559.2"
                     /locus_tag="D5S18_RS07950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07950"
                     /product="DUF6668 family protein"
                     /protein_id="WP_345789703.1"
                     /transl_table=11
                     /translation="MRAAGLLHHRLPPRAVVAPPTDRRAPIWESACPIATATGGVPRFW
                     LLGAHGGAGVSTLAWLWRRSADCGRWWPKPMSGEARFVVLVARETVAGLAAADALLRQH
                     HAGLAGASRVVGLVTVAARPGRTSAVIRRDLTLYSSLVDRWWRIGWHEPFIQQPLDALP
                     RGGVEDESSTVPKDVVRAGREVAAVVEQLNSDARTEERGL"
     gene            complement(2207..3532)
                     /locus_tag="D5S18_RS07955"
                     /old_locus_tag="D5S18_07955"
     CDS             complement(2207..3532)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013265.4"
                     /locus_tag="D5S18_RS07955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07955"
                     /product="cutinase family protein"
                     /protein_id="WP_158607834.1"
                     /transl_table=11
                     /translation="MASAHAPDARACMPLFVVGVQGTGESSPDADPRTDSGFLGDAVLG
                     PLMIRAAGKADRAYVPYQASFGGVDGGAAVPYSASVTGGIERTRQLVRDEAARCPSTVF
                     AVVGYSQGSHVASMFVQEIGRGQGVVPAEKIAAVALFADPTRNPGASLFPGAPGRDRPE
                     PAPGTGGAAVHGLPAMSAATVAGGGIGPQRDVAADFGSLTGRVVSWCTAGDLACDAPDG
                     APILRVVANIVGQSDLRDPLAALRSVSEALAFTAFKTAVSVVDEDVSGTSLASLSLNPR
                     KSLSQRMAEASDPRTPFDPDAAVRALFKVATIGLNAVSTVVRTVLAPENIAEMVGAGLV
                     TPAAGLAVLGTKIVSALPELVPPATVSRLVQQAFTAIEQNVVDNRDLLDLATWSKFGNT
                     IAAHLSYRTTPVAAGVTAASATVDWLVAIADDLAAARSDGAR"
     misc_feature    3980..3993
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.87"
                     /tool="antismash"
     gene            4110..4427
                     /locus_tag="D5S18_RS07960"
                     /old_locus_tag="D5S18_07960"
     CDS             4110..4427
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210803.1"
                     /locus_tag="D5S18_RS07960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07960"
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_120039184.1"
                     /transl_table=11
                     /translation="MSEELRVNPERLREAARFIAEKAQTIRDRVKGLDDTVGRGLLCGG
                     WRGRTASVYDESWMEWKTGADDVVAGLESSALKLVEAANRYQAQDAHTADQIARNNSRM
                     Q"
     gene            4427..4723
                     /locus_tag="D5S18_RS07965"
                     /old_locus_tag="D5S18_07965"
     CDS             4427..4723
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011210804.1"
                     /locus_tag="D5S18_RS07965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07965"
                     /product="WXG100 family type VII secretion target"
                     /protein_id="WP_120039185.1"
                     /transl_table=11
                     /translation="MSDDYSYQVNLTQLDEAVEAMASFGAEVDGILREVDQHVADLHLS
                     WSSEAASAQRDAHDRWMAGAAEMRENLDELRETARRAHTHYSDVGRTNEGMWP"
     gene            4724..6127
                     /locus_tag="D5S18_RS07970"
                     /old_locus_tag="D5S18_07970"
     CDS             4724..6127
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS07970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_07970"
                     /product="hypothetical protein"
                     /protein_id="WP_120039186.1"
                     /transl_table=11
                     /translation="MAPSFPAITIRHGEYHSAGESLAAVKDNAVDVHTALVQSLIGCEG
                     MAGTDKTGTDWAKAYDDATGIALEASAKLASAFGRTSSLLTVGAYNHAAGEAASNPQAG
                     APPTPPTPAFEPSLALFHPPASGASGPEPFGWGLIKTVSDLAWPDGHQDQLRAAKTVWH
                     SAATALVEATGPIPTAVTLLENQQSPEIPSAVRTCNEMGVNADQLATAYRTIGDGCEQF
                     AQHLDDAHSEILAELREMLIETAALEGVIQVGAFFTGGLSELGNAGVIARIGIYATRIG
                     RIITELGTKVLTVSRRIASLTTTTLKTMTSKLGRWLEQAVAKIWRGSETGLQLFSRSAT
                     RTNIDVLTSGDHIPMTEETILALARKAGVDLSGIDLHIVKDMEEARYLDFQDACGVTPS
                     EMGGRQIRFGPAAFTDEETLVATLAHEAKHVQQLRDQVRLGSDTIRGLEDEAYAAETPA
                     LARYRGEHQ"
     misc_feature    5228..5230
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6124..6396
                     /locus_tag="D5S18_RS07975"
                     /old_locus_tag="D5S18_07975"
     CDS             6124..6396
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS07975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_07975"
                     /product="hypothetical protein"
                     /protein_id="WP_120039187.1"
                     /transl_table=11
                     /translation="MTEVSFTVTDVFDIPTRAGLLVAGQLASGDITVGDVLHDASTGAS
                     ATVIGIELHGHREPGRYTLVIDRQADIRIGQHLVAPVSQIDEKTR"
     gene            6393..6815
                     /locus_tag="D5S18_RS07980"
                     /old_locus_tag="D5S18_07980"
     CDS             6393..6815
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014982794.1"
                     /locus_tag="D5S18_RS07980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07980"
                     /product="hypothetical protein"
                     /protein_id="WP_120039188.1"
                     /transl_table=11
                     /translation="MTDLDDWEQKLRRDLDEIRSNATELGKAVTAVRGQGEIPGVRVEV
                     NAAGDITNLQIAPGAMRWTSAQLTKSLLDCHQQARTDARTRAERLARKADPRLSKGISE
                     LHQTPEPTTPRPLTEEEIQAADDAYFDRMNRHGWNR"
     gene            complement(6950..9991)
                     /locus_tag="D5S18_RS07985"
                     /old_locus_tag="D5S18_07985"
     CDS             complement(6950..9991)
                     /EC_number="6.1.1.14"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928557.1"
                     /locus_tag="D5S18_RS07985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07985"
                     /product="glycine--tRNA ligase"
                     /protein_id="WP_120039189.1"
                     /transl_table=11
                     /translation="MADDAAVRTGSQPVLSMQEAILRLQTYWAGHGCVIAQPFNTEVGA
                     GTMNPATLLSVLGPEPWRVAYVEPSVRPDDSRYGENPNRLQTHTQFQVVIKPEPGNPQQ
                     LYLGSLAALGIDLDAHDVRFVEDNWTQPAIGAWGLGWEVWLDGMEITQFTYFQQVGGQN
                     LDPIPVEITYGLERILMAVQKVTHFKNLVYAPGITYGEFLGQSEYEMSRYYLDDADIAA
                     TRTLLDTYSREADRLIEHRLPIPAHSFVLKSSHAFNVLDARGAISTTERATWFQTMRRQ
                     ARSVATLWTELRAEAEHPRGIAEPLPPALPAVDPAELPAAGLLVFEIGTEELPPTVVDG
                     TAAVVEQELTRLLAGTELAHGQMRVDATPRRITVQIADIAAREPDGTQLHRGPKTVAAY
                     TADGAPTRALLGFLDARHASEDDIVRIQANGSEYVAVQTIRRGRVAADVLTGILSQLVV
                     GLRADKNMRWNDPILNFSRPIRRLLALLDRTVLPVTAGALAADRITHGHRRTPHSGINI
                     TSATDYTATLRREGILLDRGERRAAVTSAAVGLAAAHDGAIDTEAEAALIDEITNLVES
                     PIGILGTFDAEYLRLPEQILTTVMRKHQRYLPVRRADGELLPLFITLANGACDTDVVRE
                     GNENVLRARFEDATYFWKTDLRTTPDQFRSRLTALTFETRLGSMSDRSERIAALSRKLA
                     TRIDLPADDSRTLERAGALVKFDLATQMVIEMTSLAGTMAREYARRSGESDPVAEALFE
                     AELPRHHADRLPESLPGALLALGDRFDLLVAMLAIGAKFTGTSDPFGLRRAALGIVRIL
                     RAQPELSNLTFRDGLTAAADALREQGIAVDDAVLDTAEELLITRYEQRLRDEGVPVLLI
                     EAVRPSAGSPYRADRLRAEVEQARELVDREFAEIVEGLQRISRILPPGTSPSFDSEMLT
                     KPAERNLITALNNLDTSRDRPFAVWAGSTQPLVRALRAFFEEILVMDEDLAVRTARLGL
                     LSGVLHTAPPAIDWKSLHQLRSGV"
     gene            complement(10001..11395)
                     /locus_tag="D5S18_RS07990"
                     /old_locus_tag="D5S18_07990"
     CDS             complement(10001..11395)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928558.1"
                     /locus_tag="D5S18_RS07990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07990"
                     /product="radical SAM protein"
                     /protein_id="WP_120039190.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 9.1e-08,
                     bitscore: 25.8, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 2.5e-16, bitscore: 54.2,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 8.2e-07, bitscore: 23.1,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.3e-09, bitscore:
                     29.8, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSTDITGRLRYRRDLGLLFDPTSGSFYRLRNAVARLMIDQIYA
                     GTDRQAVVATVADRYHADPIRVATDLDGLLATMTAPPAQRPGPHGEALLEIDKRFDARL
                     DFPLRLEIELTAVCNWNCGFCYNVWKIDPTLSDREIRRAVRELPEKHIPTDLAMSILDE
                     CADRGCFVLRYSGGETLLHPDAMEIFEHGGRLGLYQVVFTNGHFITADRAARLAAANVR
                     CVLVSIHGDRDQHNSLTGHLRAYDKAVTAMRLLLDAGITVVAELTLVQQNTLSALDVIR
                     DAYRIGVREFGVMRYVPTGRNDDRYGVPASVTLPLIEEIDRLIATECPGMTVAWPCAQK
                     VCTSDLDTPLRSDDPTLALRFSQLAGHCESGMVWASVSYDGRLRNCPHSNVYFGQLADH
                     RLAELWPPLTERVHTAVATRDTCAGCAVADTCRGGCHLSSFFTPKTTTGLGIPTMPVAG
                     PAEIGG"
     aSDomain        complement(11159..11341)
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_D5S18_RS07990_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.20E-08"
                     /identifier="RREFam002.1"
                     /label="D5S18_RS07990"
                     /locus_tag="D5S18_RS07990"
                     /protein_end="79"
                     /protein_start="18"
                     /score="25.8"
                     /tool="antismash"
                     /translation="LLFDPTSGSFYRLRNAVARLMIDQIYAGTDRQAVVATVADRYHAD
                     PIRVATDLDGLLATMT"
     gene            complement(11392..12420)
                     /locus_tag="D5S18_RS07995"
                     /old_locus_tag="D5S18_07995"
     CDS             complement(11392..12420)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024801.4"
                     /locus_tag="D5S18_RS07995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_07995"
                     /product="hypothetical protein"
                     /protein_id="WP_120039191.1"
                     /transl_table=11
                     /translation="MLILYVGDAHFSGWSMRGRIAVREKDISFEERCIELDWPTGETAD
                     GVLTVGDLPEEREARIGCQCSFADLAAHDVERALAGSVVGMLPRVPVLVDTLTGAVASD
                     VVSIAEYLDEIAPESGVRLMGATSAHRSVIRSLCAWASHDLARLIDDAPYAVSLRSRPW
                     TDLAPAAVEQGRWVCETVAGLLDRYGGPYAVGAFSLVDVMLSTNFQQITGLGMPIADAR
                     VADYAVRLLERASVRDHLDSARAVYRAIDEAQTGSPQWILRHYRYNRQQRLLHDWQTDT
                     CVRLRNRAAERIVDLAYTGHSVDQIARTLAGEFRAGREQLTVDVLGFLDRLAPAFESGA
                     TS"
     misc_feature    complement(12556..12570)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    12944..12959
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.98"
                     /tool="antismash"
     misc_feature    complement(12977..12995)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.11"
                     /tool="antismash"
     gene            13228..13935
                     /locus_tag="D5S18_RS35605"
     CDS             13228..13935
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS35605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_239003616.1"
                     /transl_table=11
                     /translation="MDIVCSEIPDDERPEYASPADRNYLRYAKFADLDTLMFVRTRLAQ
                     QAPTVVVRDFAPSEHYDTHADVLIVIGGPPWNTKFREFLPQLPFHFEPHPLGEDDPLVV
                     PGLDDLTLTPRWTPRGELIEDLAVFTRLTLRGTIVFLLGGCLTLGVLGAARCLLDSECG
                     PGNTDYLTGRVGDNDFVLVVEARRVGGITDIADMTAVGPLLLLSRGVGENWSVVVDNTK
                     RFTDRQRSIGLGR"
     gene            13932..14666
                     /locus_tag="D5S18_RS08005"
                     /old_locus_tag="D5S18_08005"
     CDS             13932..14666
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928561.1"
                     /locus_tag="D5S18_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_08005"
                     /product="glycosyltransferase family 25 protein"
                     /protein_id="WP_120039193.1"
                     /transl_table=11
                     /translation="MTGPDGVATYVVNLPRRPDRRAWIRSQLPDTLPATYTSDLDTLID
                     GNQLTLAGLHSAGIKLFDWQIDSDNPWWNRPLKYGEIGCTIAHLACWAHAAEHTDTPNI
                     LILEDDAVLNHEFSGTLNAGLRELRRHRTRFDLLYLGRYPLEPDQATPLRGFVRPGYSH
                     CSFGYLLTRRGLTMLLAAGLSDAIVPIDEFLPAMYLPHPRADLRARFPPRLSALAFDPA
                     LVTQRPKNQAGSDTEDSRFVEP"
     gene            complement(14671..15330)
                     /locus_tag="D5S18_RS08010"
                     /old_locus_tag="D5S18_08010"
     CDS             complement(14671..15330)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019928565.1"
                     /locus_tag="D5S18_RS08010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_08010"
                     /product="DapH/DapD/GlmU-related protein"
                     /protein_id="WP_120039252.1"
                     /transl_table=11
                     /translation="MNPVDLRGEVRFGEGVVVGEQCVLGCPKETRIRAAQRGGCSPGDP
                     VVLGDRCLLFNQVIVYEGTTLGSDCVVEDRIRIGYGCVLGDRVRVVHGAYICDRVRIGE
                     DACVAGFVCDAASIGNRSTVMGDLVHEYTRPDLGWWGVDEMAPSVADDAVVGFGARVIG
                     GVRIGSRSYVAAGAVVTKDVPSGHVVTGTNVHTPIGEWHGERLGALIERWMAGVDR"
     gene            complement(15327..16493)
                     /locus_tag="D5S18_RS08015"
                     /old_locus_tag="D5S18_08015"
     CDS             complement(15327..16493)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="D5S18_RS08015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_08015"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_239003617.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.5e-09, bitscore:
                     30.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSIDYEGVIERGVGTFGGSEAQAHRRRLGVAAKALTTLTGCRWR
                     SPDSGLPRCAAFRMIAVVVASCLSCSPRHWEAQSQFGSSSAGLATFGQTLNIDLVRGWC
                     AEMLYGTMGSSAVDRGDGAGRVERVGLRSVDGLELDAVVHTSERPDVCGSVLLVHGITV
                     DLDEGGGMFVRLADRLAGVGFEVVRFSFRGHGGSDGTQRGVTVAGECLDLQAAVELARG
                     RRSGPMSVVAASFGAVSTVLSLPWLDEELHRLVLWNPVLDLHHTFLEPELPWGADNFGP
                     VQRNQLRDKGFLTVDGEFELGRVLFGEFACYRPLDVFLASRVSTLIVHGDRDGAVSYPI
                     AAEAAWKRPSTLLHTVVGSDHGFDSREREDEAITVTVDWLVDQACAAS"
     misc_feature    complement(15678..15680)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    16482..16497
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.83"
                     /tool="antismash"
     gene            complement(16522..17028)
                     /locus_tag="D5S18_RS08020"
                     /old_locus_tag="D5S18_08020"
     CDS             complement(16522..17028)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="D5S18_RS08020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_08020"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_203236652.1"
                     /transl_table=11
                     /translation="MSQVLRSPGASDTPIAAREFDHPDAAALLAAYAAERQEMVGFVDP
                     PGLDNAAQYEPPTGVFLVAYTNTGDAIACGGLRAYLSCDSIAEIRKMYVAPAHRGRGLG
                     HRILAELEQHASAHGVREVRLETGSYNRPALHLYPSAGYRPIPPYVPGRPSFNRAFAKK
                     LSSSA"
     gene            complement(17072..18478)
                     /locus_tag="D5S18_RS08025"
                     /old_locus_tag="D5S18_08025"
     CDS             complement(17072..18478)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS08025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_08025"
                     /product="hypothetical protein"
                     /protein_id="WP_120039195.1"
                     /transl_table=11
                     /translation="MHDAPLENPAPEAQTMMLRTVLGEAGWGPRDLTRAVNMWLAQRGR
                     PGDRIDATAAYSWVRSGYCPHGDIAEVVATVLGDRLGRYITASQLWPGHTRAERITCGT
                     RLPSEGSIDEAIRSLDQLAAGIRPAPISGSDLAAAAITGLRDPIELRGGSQGRDRIHHS
                     QAGLIADHVTALRQLDDCQGGGALSLRYVSRELATVIDLLRSGSHEPAVQDSLLTSIAD
                     LAQLAGWMSFDSGATETAQRYLVLGIRIARAARDGDRAINAAGMLAYIAAEVDAGHDSV
                     AITEAAATLPTSSLLLKARLAGRQASAHAAAGDIAAFRAASDRAQHLLDTARRDHTEPY
                     LYYLTPDQLAAEAGYSLVQLARRTEVHRRPLLRQASDLLTPRANLDRDPGYQRSAVLHG
                     CQLAQVHLMLGDLDGVVAAARRATTMLGDVQSGRCVTKLRGLHRDLLQRRRSRVVCEFL
                     PELEHILGAL"
     misc_feature    complement(18047..18049)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18750..19025
                     /locus_tag="D5S18_RS08030"
                     /old_locus_tag="D5S18_08030"
     CDS             18750..19025
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS08030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_08030"
                     /product="hypothetical protein"
                     /protein_id="WP_147403894.1"
                     /transl_table=11
                     /translation="MISDLRVARMAIRLAHNHIGEVRIPAMSSRQERAHGAKLRPDRND
                     DCRVDITGFSNAAEAGAVYASHIDHGPHCLLWLAALAYESCGLQDE"
     gene            19030..19299
                     /locus_tag="D5S18_RS08035"
                     /old_locus_tag="D5S18_08035"
     CDS             19030..19299
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS08035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_08035"
                     /product="hypothetical protein"
                     /protein_id="WP_147403895.1"
                     /transl_table=11
                     /translation="MTAGHVLVAFGLAVLLAELLVAVLGCGGTTDVDHPAPVGGFTIAE
                     AHRATQQHRECSPRECECVREAWRTLVLAGRCAPTGELHRMLYG"
     gene            19366..19998
                     /locus_tag="D5S18_RS08040"
                     /old_locus_tag="D5S18_08040"
     CDS             19366..19998
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS08040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_08040"
                     /product="hypothetical protein"
                     /protein_id="WP_147403896.1"
                     /transl_table=11
                     /translation="MVVPRDDLVAPGVPLTGLDAIDAAFAEQMRLLRAVFEVRRTVADT
                     GDGVFEVGGAVSVVDSHGADTAGWCEFYRETCRFDVAVRPEVGLIYVTAGARIGSVRMP
                     AELGALVEARLGDAGVRLGPVIGLRERQWVLLVEPDIPDRIDIYAGMFRHAVSIARAGA
                     QIALPTFGTGRTRLRTWLRQPRDAYLPAGTAVLAAVTACFPVRTAPP"
     gene            20723..20884
                     /locus_tag="D5S18_RS34805"
     CDS             20723..20884
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS34805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158607835.1"
                     /transl_table=11
                     /translation="MNDQTLTALHSWARGIILGLAVITVIDAVQDLADWLAGRAGQPGR
                     NSDSIGDR"
ORIGIN
        1 ccgcgaggag tgtgtgcgaa ccccgcggcc atcccgttgc tgatgtgggt ggggccgtcg
       61 gaggtggaga acggcaccga gaccccgtat acgcgttgcc agccaccgcg tccggtcgtc
      121 cccaagggcg gggcgctcag ccacagcggg tcgagttcgc ttaccgggga ggcggtttgg
      181 ggcagcggtc gcccggctgc ggcggcgggg atatcgacgc gacgaccgta gacatcggtg
      241 accggggtgc cgaacccgtc ccccaccggg acatccggac tcgggatcac cgattgtggt
      301 gggtcagcgg agatatcgcg cgacgctgcg tgcttgtaga tgagggcggc gatcagcgcg
      361 gtggtcagcg caagcgccgc gagggtgatc acgacggttt tggagcggac gattctgccg
      421 tgcgaggtgt tcatcggttc tccaatctca ctgtgtcgtg cggaatctcg cgtatcgttt
      481 cgaccgtggg ctgtgtcgag tccgggtgcg gcaggtccag cagccagtcc tcgcccagcc
      541 acaccacccg gacatgagtc gcggccagag aactgtcggg atagcgggtg taggcggtga
      601 ccgccgcgcg tgccttcgac aggtaggcgg tgacccggta gccgataatt gttggcgcgg
      661 tggccttctc agcgggcttg gtgatcgaca ccaacgttcg tgccgcgatc caggcgtctt
      721 tgcccggtcc cggcgcgagt tcgctcgcgg cgatcggtga ccaggtccgg tcgggcgcga
      781 ccgacatccg cacggtgtgc acgatcgccg ccagcgcggc accggccggc gtatcggcga
      841 atcccgtcgc cgccgtggcg gaatgggtgt ggggaccttg gtcggcgatc ggaatggcga
      901 tgccctggta gtcaatccag tgcagcccgg tcggcggcgc ggcgacatct gtcccgacaa
      961 cgggatcgtc gatggcctga ccgcaccctg aaagggcgag aactcccgcg aacagcacgg
     1021 cgacgattcg ggggttcatg acgcgttccc gacgactgtc gcggcgatcg ggagcgcgac
     1081 cgagcagatc ccggcggcga tcagcgtgac gacgatggcg gtgctggtgt gtcggccctg
     1141 gatctccggt tgccgccgct ccatccacaa cttcgcaccg caggccacaa tcgtgcccag
     1201 caggatcagt tcacagcccc acagcaacca ggacagtagc tgcgcgagtg gggcggtcac
     1261 ctcgctcggc agcgacgccg cgatgcgaaa taccttggtc ggcatggcga tcacccgcgc
     1321 ctacgtggcc aggaccacgg tattgatcag ggccgacgcc gacgtggcga cgatgccacc
     1381 gatcagggcc gccaccacga tcttgggcga ctccagcgcg ccaccgttcc atttctccca
     1441 cgcgaatttc ccacccgcgt agatgattcc ggcgacaccg gcgagcatca caccccacag
     1501 cagccaccga accagaagga tcagtttctc cgatcccggt ggagtatccg cagtgatctg
     1561 atcgatcgcc tcgaaaccgg ccaacacgat tgtgtgcatc acaaccccct ttcctcggtc
     1621 cgcgcatcac tgttcaactg ctcgaccacc gccgccacct cacggccggc ccgcacgaca
     1681 tcctttggga ccgtgctcga ttcgtcctcg acgccaccgc gaggcagggc atcgagtggt
     1741 tgctggatga acggctcgtg ccagccgatg cgccaccagc gatcgaccag cgagctgtag
     1801 agggtcaagt cacggcggat caccgccgaa gtacgccccg gccgcgccgc caccgtgacc
     1861 aaaccgacga cccggctggc accggccagt cccgcatggt gctggcgcag cagcgcatcg
     1921 gccgccgcca gaccggccac ggtttccctg gccaccaaca ccacgaaccg cgcctccccc
     1981 gacatcggct tcggccacca gcgcccgcaa tcggccgacc gccgccacaa ccacgccaac
     2041 gtcgacactc ccgcaccacc atgcgcaccc aggagccaaa acctcggaac accaccggtc
     2101 gctgtcgcga tcgggcaggc actctcccat atcggtgccc gccgatcggt cggtggagcg
     2161 acaaccgccc gaggcggcaa ccggtgatgc agcagccctg cggccctcac cgagcaccat
     2221 ccgagcgagc cgccgccaag tcgtcggcga tggcgaccag ccaatcgaca gtggccgacg
     2281 ccgcggtcac gcccgccgcg actggagtgg tccgatacga caaatgcgcg gcaatcgtgt
     2341 tgccgaactt cgaccaggtc gccagatcca gcagatccct gttgtccacc acgttctgtt
     2401 cgatggctgt gaatgcctgc tgcacaaggc gactgaccgt cgcaggcgga accagctccg
     2461 gcaacgccga cacgatcttc gtgccgagca ccgccagtcc ggcagccgga gtcaccaggc
     2521 cggcccccac catctccgcg atattctccg gtgccagcac agtcctcacg accgtcgaga
     2581 ccgcgttcaa cccgatcgtc gccaccttga acaacgcccg caccgccgca tccggatcga
     2641 acggagtccg cggatcggag gcttcagcca tccgctgcga caacgacttc cgcggattca
     2701 gcgacaaact cgccaacgac gtccccgaaa cgtcctcgtc gacgaccgag accgccgtct
     2761 tgaacgcggt gaacgccaac gcctccgaca ccgaccgcaa cgccgccaac ggatcccgca
     2821 gatccgactg gccgacgata ttggccacca cccgaagaat cggcgcacca tcgggcgcat
     2881 cgcaggccag atcaccagcc gtacaccacg acaccacccg cccggtcaac gaaccgaaat
     2941 ccgccgccac atcacgctgc ggcccgatcc cacctccggc caccgtggcc gccgacatcg
     3001 ccggaagccc atgcaccgcg gccccaccgg tccccggcgc gggctcgggc cgatcacggc
     3061 caggtgcacc gggaaacaag gacgcacctg gattccgcgt cggatcggcg aaaagagcca
     3121 ccgcagcgat cttctcggct ggaaccacac cctgccctcg gccgatctcc tgaacgaaca
     3181 tcgacgcgac atgcgagccc tgtgagtagc cgacgacagc gaacaccgtg ctcgggcacc
     3241 tggccgcctc gtcgcgaacc aattgccttg tccgctcgat accgccggtc accgacgccg
     3301 aatacggaac ggccgcaccg ccatccacac caccaaagga agcctgatag ggcacatacg
     3361 cccgatccgc cttcccggcc gcgcgaatca tcaacggccc cagcaccgca tctccgagga
     3421 acccggaatc ggtgcgtgga tcagcgtccg gcgacgattc gccggtgccc tgcaccccga
     3481 ccacgaacaa gggcatacaa gcccgcgcgt ccggcgcatg cgccgaagcc accgcaccca
     3541 cgctcgaaac cgcaagagcc gataccgcaa ccgccgacaa cccgcacaga aacggaaccc
     3601 ttcgccggat cagaaaatct gacattgaac gcctccctcc cacaacagat cccgaggccg
     3661 cgaacgtgct cagcgcacgc gatcacgacc gcaaagcacg acgatgctca cgaagcccgc
     3721 agcaccagcc ggcacaggat caattcggtg atttaatgga agacgcgtga aacagcttcc
     3781 aagacaaggg aactggtcac gccttcgggt tctgtcaaca cagatgcccg gcaatcactc
     3841 cgccgcctcg gaccttcgac caaggcactt ggggtgccca acgcttcgcg acctcaacag
     3901 tatttgctgt atgtgtgctc acgaatgggt acggaccagg gtagacccca agtgttgtcg
     3961 ctgcaagaaa gacttcttgc gaacccctgt ttgaaaaccg acgggcgcgg tcaaccctgc
     4021 caattggccc gcacagggcc tttcgcacag tcctcgacga cggagtccta tagtgctcta
     4081 aaaagcgggt cgagctgcgg ggaggcgtga tgtcggagga gttgcgggtc aatccggagc
     4141 ggttgcgtga agcggcgcga ttcatcgccg agaaggcaca gacgattcgc gatcgagtga
     4201 aagggctcga cgataccgtc ggccggggac tgctctgcgg cgggtggcgt ggaagaacgg
     4261 cctcggtcta cgacgagagc tggatggaat ggaagaccgg cgcggatgat gtcgtcgccg
     4321 gcttggagtc ctcggcattg aaactcgtcg aggccgccaa ccgctaccag gcacaagacg
     4381 cccacaccgc agaccagatc gcccggaaca acagtcggat gcagtgatgt ccgacgacta
     4441 cagctaccag gtgaatctga cgcaactcga tgaggcggtc gaggccatgg cctccttcgg
     4501 cgccgaggtc gacggcatcc tgcgcgaggt cgatcaacat gtcgccgatc ttcatctgtc
     4561 ctggtcgagc gaggccgctt cggctcaacg ggatgcccat gatcggtgga tggcgggcgc
     4621 ggccgagatg cgggaaaacc tcgacgaact gagggagacc gcgcgccgcg cgcacaccca
     4681 ctactccgac gtcggccgca ccaacgaggg gatgtggccg tagatggcac cgtcattccc
     4741 ggccatcacc atccgccacg gcgaatacca ctcagcaggc gagtcgctcg ccgccgtgaa
     4801 ggacaacgcc gtcgacgtcc acaccgcgtt ggtgcaatcg ctgatcgggt gcgaagggat
     4861 ggccggaacc gataagaccg gaaccgactg ggccaaggca tacgacgacg ccaccggcat
     4921 cgcgctcgaa gcctccgcca aactggcctc ggcattcggt cgcacgtcct ccctgctcac
     4981 ggtcggggcc tacaaccacg ccgcaggaga agccgcctcc aacccgcaag ccggtgctcc
     5041 cccgacacca ccaacccccg ccttcgaacc ttcgctggcg ttgttccacc cgccagcctc
     5101 cggcgcgagc gggccggaac cgttcgggtg gggtctgatc aagaccgtgt ccgacctcgc
     5161 ctggcccgat ggacatcagg atcaattgcg agcggccaag accgtatggc acagcgccgc
     5221 aacagcatta gtcgaggcaa ccggccccat ccccacagcg gtaacgctat tggagaatca
     5281 gcagtccccc gagatcccca gcgcggtgcg gacctgcaac gagatgggcg tcaacgccga
     5341 ccaactggcg accgcctacc gtacgatcgg cgacgggtgc gagcaattcg cccagcatct
     5401 cgacgatgcc cactccgaaa tcctcgccga actccgagaa atgttgatcg agaccgccgc
     5461 gctcgaaggc gtcatccagg tcggcgcgtt cttcaccggc ggactctccg aactcggcaa
     5521 cgccggtgtc atcgcccgaa tcggcatcta cgccacccga atcggacgca tcatcaccga
     5581 actcggcacc aaggtcctca ccgtctcccg ccgcatcgcg agcctgacca ctacgaccct
     5641 caaaacgatg acctccaaac tcggccgctg gctcgaacaa gcggtagcga aaatctggcg
     5701 aggcagcgag accgggctgc aactgttctc ccgcagcgcg acacgaacca acatcgacgt
     5761 cctcacctcc ggcgaccaca tccccatgac ggaagaaacg atcctcgctt tggcccggaa
     5821 agccggagta gacctgtctg gtatcgacct ccatatcgtc aaggacatgg aggaggcccg
     5881 ctatctcgac ttccaggacg cctgcggagt caccccttcc gagatgggtg gcagacagat
     5941 ccgcttcggt cccgcggcgt tcaccgatga ggaaaccctc gtcgccaccc tcgcccacga
     6001 agccaaacac gtccagcaac tccgcgacca ggtccgcctc ggctccgaca ccatccgagg
     6061 actcgaagac gaagcctacg cagccgaaac acccgccctg gcccgatacc gaggagaaca
     6121 ccagtgaccg aggtcagctt caccgtcacc gacgtattcg acatccccac ccgcgccgga
     6181 ctcctcgtcg ccggacaact ggcctccggg gacatcaccg tcggcgacgt actgcacgac
     6241 gcatcgaccg gcgcgtccgc gaccgtgatc gggatcgaac tccacggtca ccgcgaaccc
     6301 ggacggtaca ccttggtcat cgaccgacaa gccgacatcc gcatcggaca acacctcgtc
     6361 gctccggttt cccagatcga cgagaagacc cgatgaccga cctcgacgac tgggaacaga
     6421 agctccgtcg ggacctcgac gaaattcgaa gcaacgcaac cgagctcggc aaagcggtca
     6481 cagcggtccg tggacagggc gagatacctg gcgtcagagt cgaggtcaac gccgcaggcg
     6541 atatcaccaa tctacaaatc gcacccggtg ccatgcgctg gaccagcgcc caattgacca
     6601 aatccctcct cgactgtcat caacaggccc ggaccgacgc ccgcacgcgc gcggaaaggc
     6661 ttgcccgcaa ggccgatcca cggctcagca aaggcatatc cgaactccac cagacccccg
     6721 agccaactac accacgaccg ctgaccgagg aggagatcca agccgcggac gacgcgtact
     6781 tcgatcgcat gaaccgacac ggctggaaca gatagtcagc agacgaatct ctgggcgtcg
     6841 acgccgccgt ggcggtcgcg gatccagtcg aatacggtgg ccgtctcgtt tgaggccatg
     6901 ggatcgacaa tcggcgactt tatgtcgtgt tctcggccgt actgcttccc tatacaccag
     6961 atcgcaactg gtgcaaggat ttccagtcga tcgcgggtgg tgcggtgtgc agaacgccgg
     7021 agagtagacc gaggcgcgcg gtacggactg caagatcctc gtccattacg agaatctctt
     7081 cgaagaacgc ccgcaaggca cggacaagcg gctgcgtcga accagcccac acggcgaatg
     7141 gccggtccct actcgtgtcg aggttgttga gggcggtaat cagattccgc tccgccggct
     7201 tggtgagcat ctcggaatcg aacgaaggtg acgtgcccgg cggcaggata cgcgaaatgc
     7261 gttgcagtcc ttcgacgatc tcagcgaact ctcggtcgac gagttcgcgt gcctgttcaa
     7321 cctcggcacg caatcgatcg gcgcggtacg ggcttccagc cgagggccga acggcctcga
     7381 tcaggagaac cgggacacct tcgtcgcgca atcgctgttc gtagcgcgtg atgaggagtt
     7441 cttcggcggt gtccaggacg gcatcgtcga ccgcgatgcc ctgttcgcgc agtgcgtccg
     7501 ccgcggcggt gagtccgtcg cggaaggtga ggttgctcag ttctggctgg gcacggagaa
     7561 tgcgaacgat gccgagggcg gcgcggcgca ggccgaaagg gtccgatgtc ccggtgaatt
     7621 tggcaccgat cgcgagcatg gcgaccagca gatcgaaacg gtcgccgagt gcgagaagtg
     7681 cacccggaag cgattcggga agccggtcgg cgtggtggcg tggtagttca gcctcgaaca
     7741 gggcttcggc gactggatcg gattcgccgg atcggcgggc gtactcgcgg gccatggtgc
     7801 cggcgaggga ggtcatttcg atgaccatct gggttgccag gtcgaatttc accagtgcgc
     7861 ccgcgcgttc cagtgttcgg gagtcgtcgg ccgggagatc gattcgcgtg gcgagttttc
     7921 gactgagtgc ggcgatgcgt tcggagcggt cgctcatgga tccgaggcgg gtttcgaagg
     7981 tgagtgcggt cagccgggat cggaattggt cgggcgtggt gcgcaggtcg gtcttccaga
     8041 agtaggtggc gtcttcgaac ctggcccgca ggacgttctc attgccctcg cgcacgacgt
     8101 cggtatcgca ggcgccgttg gcgagagtga tgaacagtgg cagcagctca ccatcggcgc
     8161 gacgaaccgg cagatagcgc tggtgtttac gcatgacggt ggtcaggatc tgctcgggta
     8221 gccgcaagta ctcggcatcg aatgtgccga ggatgccgat cggggattcg accaggttcg
     8281 tgatctcatc gatcagggct gcttcggctt ctgtatcgat ggctccgtcg tgtgcggcgg
     8341 ccaggccgac agcggccgag gtgacggcgg cccggcgctc accgcgatcg aggaggattc
     8401 cttcccggcg tagggtcgct gtgtagtcgg tggcgctggt gatgttgatc cccgagtgcg
     8461 gagttcggcg gtggccgtgg gtgattcggt cggcggccag tgctcccgca gtgactggga
     8521 ggacggttcg atcgaggagg gcgagcagcc ggcgaatggg gcggctgaag ttcaggatcg
     8581 ggtcgttcca gcgcatgttc ttgtccgcgc gcaatccgac gaccagctga gagaggatgc
     8641 cggtcagaac atcggctgcg acgcgtccgc gccgaatagt ctgtacggcg acgtattccg
     8701 atccgttcgc ctggatgcgg acgatgtcgt cttcggaggc atgcctcgcg tcgaggaatc
     8761 cgagcagcgc gcgggtcggt gcgccgtcgg cggtgtaggc ggcgaccgtc ttcgggccgc
     8821 gatggagttg tgtcccatcg ggttcgcggg cagcgatatc ggcgatctga acggtgattc
     8881 gccgcggcgt ggcatcgacc cgcatttggc catgggccag ctcggtgccg gcgaggagcc
     8941 gagtcagttc ttgttcgacc accgcggcgg tgccgtcaac gactgttggc gggagttcct
     9001 cggtgccgat ctcgaatacg agcaacccgg cggcgggcag ttcggccgga tctactgctg
     9061 ggagcgccgg cggcaatggt tcggcgatgc cgcgaggatg ctctgcttcg gcgcggagtt
     9121 cggtccacag tgttgcgacg gagcgggcct gacgtcgcat ggtctggaac caggtggctc
     9181 gttcggtggt ggagatggct ccgcgagcat cgaggacgtt gaacgcgtgc gaactcttga
     9241 gcacgaatga gtgggcgggg atcgggagcc gatgttcgat gagccggtcg gcttcgcgtg
     9301 agtaggtgtc gagcagggtg cgggtggcgg cgatgtccgc gtcgtcgagg tagtagcgcg
     9361 acatttcgta ttcggattgg ccgaggaact cgccgtaggt gatgccgggt gcgtaaacga
     9421 ggttcttgaa gtgggtgacc ttctgcacgg ccatgagaat gcgttcgaga ccgtaggtga
     9481 tctcgacggg aatggggtcg agattctggc cgcccacttg ctggaagtag gtgaactggg
     9541 tgatctccat gccgtcgagc cacacctccc agcccaggcc ccaagcgccg atggcgggct
     9601 gggtccaatt gtcctcgacg aaacgcacat cgtgcgcgtc caggtcaatg ccgagcgcgg
     9661 ccagggatcc gaggtagagc tgctgcgggt tgccaggttc cggcttgatg acgacttgga
     9721 actgcgtatg ggtctggagc cggttggggt tttcgccgta gcggctgtcg tcggggcgta
     9781 cggagggctc gacgtaggcg acgcgccagg gttcggggcc gagcacgctc agcagagtgg
     9841 ccggattcat cgttcccgca ccgacttcgg tgttgaatgg ctgcgcgatc acgcaaccgt
     9901 gaccggccca ataggtttgg agtcgaagaa tcgcttcctg catggacagg accggctgcg
     9961 atcctgtgcg aacggctgcg tcgtcggcca tcgggatacc ctatcctccg atctcggcgg
    10021 gtccggcgac gggcatagtt ggaattccca ggccggtagt ggttttcggg gtgaagaaac
    10081 tggacagatg acaacctccc cggcatgtgt ccgccacagc gcagcccgca caggtgtcac
    10141 gggtggcgac cgcggtatgc acgcgttcgg tgagcggcgg ccacagttcg gcgagccggt
    10201 ggtcggcgag ctgaccgaag tagacgttgc tgtgggggca gttccgtagc cgcccgtcgt
    10261 agctgacgct cgcccagacc attccggatt cacaatgccc ggccagttgg gagaaccgca
    10321 gcgcgagagt gggatcatcc gatcgcaggg gtgtgtcgag gtcgctggtg cacactttct
    10381 gcgcgcacgg ccaagcgacg gtcatgccgg ggcattcggt ggcgatgagt cggtcgatct
    10441 cctcgatcag aggcaatgtg accgacgccg ggacgccgta tcggtcgtcg ttgcggccgg
    10501 tcggcacgta gcgcatgaca ccgaattcgc gtacgcctat ccggtaggcg tcgcggatga
    10561 catcgagcgc gctgagcgtg ttctgctgaa ccagagtgag ttcggcgacc acggtgatgc
    10621 ccgcgtcgag cagcagccgc atggcggtga cggctttgtc gtaggcgcgg aggtggccgg
    10681 tgagcgaatt gtgctgatcg cggtcgccgt ggatggacac caggacacag cgcacattcg
    10741 cggcggccag gcgggcggcg cggtcggcgg tgatgaaatg cccgttcgtg aacaccacct
    10801 gatagaggcc gagtcggccg ccgtgctcga agatctccat ggcgtccgga tgcagcaacg
    10861 tctctccacc gctataccgg aggacgaagc atcctcggtc ggcacattcg tcgaggatcg
    10921 acatcgcgag atcggtgggg atgtgtttct ccggcaactc gcggactgca cggcgaatct
    10981 cgcggtcgga cagggtgggg tcgatcttcc acacgttgta gcaaaagccg cagttccaat
    11041 tgcagaccgc agtcaattcg atctccagcc gcaatgggaa atcaagccgg gcgtcgaatc
    11101 gtttgtcgat ctcgagcagc gcctcgccgt gtggaccggg ccgctgtgca ggtggcgcgg
    11161 tcatagtggc cagcaggcca tcgaggtcgg tggcgacgcg gatcggatcg gcgtggtatc
    11221 ggtcggcgac ggtcgcgacg acggcctgcc gatcggtgcc cgcgtagatc tggtcgatca
    11281 tcaaccgcgc caccgcatta cgcagacgat agaaagatcc ggaggtggga tcgaaaagca
    11341 gtcccaggtc gcggcggtag cgcagccgtc cggtgatatc ggtcgaagtc gtcatgacgt
    11401 ggccccgctt tcgaatgccg gtgccaggcg atcgagaaac ccgagcacat cgaccgtcaa
    11461 ctgttctcgc ccggcccgga actcgccggc caacgtccgg gcgatctggt ccacggagtg
    11521 accggtgtag gcgagatcga cgatgcgctc ggcggcacgg ttgcgcagtc gaacacaggt
    11581 gtcggtctgc caatcgtgca gcagcctctg ctgccggttg taccggtagt gccgcagaat
    11641 ccattgcggg ctaccggttt gtgcctcatc gatcgccctg tacacagcgc gggccgaatc
    11701 gagatggtcg cgcaccgacg cccgttccaa cagccgcacc gcgtaatcgg cgactcgagc
    11761 gtcggcgatc ggcatgccga ggcccgtgat ctgctggaag ttcgtcgaca gcatgacatc
    11821 gaccaggctg aacgccccca ccgcgtacgg accgccgtac ctgtccaaca atccggccac
    11881 ggtttcgcac acccaacgcc cctgctcgac tgctgccggt gccaggtccg tccacggccg
    11941 cgagcgaagc gataccgcgt acggagcgtc atcgatcaac cgagcgagat cgtgcgaagc
    12001 ccaggcgcac agcgaccgga tcacagagcg gtgagccgag gtggcgccca tcaaccggac
    12061 accggattcg ggcgctattt catcgaggta ttcggcgatc gacaccacat ccgacgccac
    12121 cgcacctgtg agggtgtcga ccagtaccgg cacgcgcggc aacatgccga ccacggatcc
    12181 ggccagcgca cgttcgacgt cgtgcgccgc gagatcggcg aagctgcact ggcatccgat
    12241 gcgcgcttct cgttcttcgg gcagatcgcc aacggtcaga acaccgtcgg cggtctcgcc
    12301 cgtgggccag tcgagttcga tgcaacgttc ctcgaatgaa atatccttct cccgcaccgc
    12361 gattcgaccg cgcatcgacc agcccgagaa atgcgcgtcc ccgacgtaca agatcaacat
    12421 ccccaaccct tcccctctgt gactgctttc gggagagccg aacgcgccgg atctcggcac
    12481 gctcggttcc gaagggcatc agttgcactg gcggctgatg agcaccttgg tctctacttc
    12541 cggcgattcg tactcctcga cggcggtgat cgtcgtttcg ttgtccatga ctctccttcc
    12601 ctccgaatgt ttttcaggtg gcgaacaccc ccgagtcttc ccggcgcgcc tcaaccgggc
    12661 catcccttcc gtatgccgta tccctggaca tctcgccggg actgctggac atatggtgga
    12721 cacatggtgc acagctcacc gccatcgctc gatcatgtga gggagtgctt gacgaaactg
    12781 cggcagggac cagctctggc gcggcctacc gtattgctga gtgcgctcga cgatccgatg
    12841 cgcgcctacc tatgtcgtga ccgcggctat tctcccggct ccgtggaaca gatcacggcg
    12901 gtgtccgcca cgatccggaa cgcgatcgat cacctgtccg acgacgaacg cctgtacgcc
    12961 caagtcgatt tcaatctgca tcctgaacac cactttgcca ccctcaccga tcggcaggag
    13021 tccttggcgt ccgaccagga atgtgcctcc aaaactgttc ggcggcactc cgcgagggct
    13081 ctggacacac tcgcctacct gctgctcgcc cctccgggtc gagccagcca tgtgccggaa
    13141 ccccctgagc gagacgaata ttcaacacag attcaaccca gatcgaaccg agtgcgcgag
    13201 ttctggcatc tgcatccggg tgcacgagtg gacatcgttt gttcggagat ccccgacgat
    13261 gagcggccgg agtacgcctc cccagcggat cggaactacc tgcggtacgc gaagttcgcc
    13321 gacctcgaca cactcatgtt cgtccgcacg cgactcgcac agcaggcacc cactgtggtg
    13381 gtgcgcgatt tcgccccctc cgaacactac gacacccacg ccgacgtcct gatcgtgatc
    13441 ggcggcccgc catggaacac caaattccgg gaattcctgc cgcagctacc gttccacttc
    13501 gagccacatc cgctcggcga ggacgacccg ctcgtcgtcc ccggcctcga tgacctcacc
    13561 ttgaccccgc gttggacgcc acgcggtgaa ctgatcgaag acctcgccgt attcacccga
    13621 ctcaccctgc gtggaaccat cgtcttcctg ctcggcggct gcctgactct cggcgtactc
    13681 ggcgctgccc gctgccttct cgacagtgaa tgtggacccg gcaacaccga ctacctgacc
    13741 ggccgcgtcg gcgataacga tttcgtgcta gtcgtcgagg ctcgccgcgt cggcggaatc
    13801 accgatatcg ccgacatgac cgcggtcggg ccgttgctgc tgctgtcacg aggcgtcggc
    13861 gagaactggt cggtcgtcgt ggacaacacc aaacgattca ccgaccggca gcgttcgatc
    13921 ggactgggaa ggtgaccggc ccggatggcg tcgccaccta cgtcgtcaat ctgcctcgac
    13981 gcccagatcg ccgcgcctgg atccgttctc aacttcccga cacgctgccc gccacctata
    14041 cctccgatct cgacacgctc atcgacggca accagctcac ccttgccgga ttgcactccg
    14101 ccggcatcaa actgttcgac tggcagatcg actccgacaa cccgtggtgg aatcggcccc
    14161 tgaaatacgg cgaaatcggc tgcaccattg cccatctcgc ctgctgggca catgccgccg
    14221 aacacaccga cacacccaat atcctgatcc tcgaagacga cgcggtcctg aaccacgaat
    14281 tcagcggcac cctcaacgcc ggactgcgcg aactgcggcg gcaccgcacg cggttcgacc
    14341 tgctctatct tggccgctat cccctcgaac ccgatcaggc cacgccacta cgaggattcg
    14401 tccgacccgg atacagccat tgcagcttcg ggtacctact cactcgccgc ggcctcacga
    14461 tgctgctggc cgccggactc tccgacgcga tcgttccgat cgacgaattc cttcccgcca
    14521 tgtacctgcc gcatccacgc gccgatctgc gcgcgagatt cccaccccgc ttgtccgcct
    14581 tggcattcga cccggccctc gtgacccaga ggccgaagaa ccaagcaggc agcgacaccg
    14641 aggactccag gttcgtcgaa ccgtgagtct ctatcgatcg actccggcca tccatcgctc
    14701 gatcagcgca ccgaggcgtt caccgtgcca ctcgccgatc ggagtgtgca cgttggtgcc
    14761 tgtcacgaca tgacccgaag ggacatcctt ggtcactacc gcacccgccg ccacgtagct
    14821 gcgcgacccg atcctcacgc ccccgatcac tcgcgccccg aatccgacga ccgcgtcgtc
    14881 ggcgacgctc ggagccatct cgtccacgcc ccaccacccc aggtccggac gcgtgtattc
    14941 gtgcaccagg tcgcccataa cggtggacct gttcccgata gacgctgcgt cacaaacgaa
    15001 tccggccaca caagcatctt cgccgatccg aacacggtca cagatgtacg caccgtgtac
    15061 gactctgaca cggtcgccga gcacacatcc gtatccgatt cggatgcggt cctccacgac
    15121 gcaatccgat ccgagtgtgg tgccctcgta gacgatgacc tggttgaaca gaaggcagcg
    15181 gtcccccagc acgacaggat ctcccggcga acagccgccg cgctgggccg cacggatccg
    15241 tgtctccttc gggcacccca gcacacactg ctcgcccaca accacaccct cgccgaaccg
    15301 cacctcccca cgcagatcca ccggattcat gacgcggcgc acgcctggtc gaccagccag
    15361 tcgacggtca ccgtgatcgc ctcgtcctcc cgctcccgcg aatcgaaccc gtgatcggaa
    15421 ccgaccactg tatgcaacag agtcgacggc cgcttccacg ccgcctcagc ggcaatggga
    15481 tacgacaccg ccccatcccg atcgccgtga acgatcaacg tcgaaacccg actggccagg
    15541 aacacatcca acggccggta acaggcgaac tcgccgaaca acacccgccc caactcgaac
    15601 tcgccgtcca ccgtcaagaa ccccttgtcc cgcaactggt tccgctgcac aggaccgaaa
    15661 ttgtccgccc cccacggtaa ttcgggctcc agaaacgtgt gatgcagatc gagcaccgga
    15721 ttccacaaca ccaaccgatg caactcctcg tccagccacg gcaacgacaa caccgtggac
    15781 acagcaccga aactcgccgc caccaccgac atcgggccac tgcgacgtcc ccgcgccaac
    15841 tcgaccgcag cctgcaaatc caggcactcc ccggccacgg tcaccccacg ctgcgtacca
    15901 tcgctgccgc cgtgccctcg aaacgagaac cgcacaacct cgaaccccac cccggccagc
    15961 cgatccgcca gccgcacgaa cataccgcca ccctcgtcca gatccaccgt gatgccgtgc
    16021 accaacagca ccgatccgca cacatccggt ctctccgacg tatggacgac ggcatccaac
    16081 tcgaggccat ccaccgacct caaaccgact cgctccaccc gaccagctcc gtcccctcgg
    16141 tcgaccgctg aagaacccat cgtcccgtac aacatctccg cgcaccatcc ccgaaccagg
    16201 tcgatgttca gggtctgccc gaatgtggcc agacccgccg aagacgatcc gaattgcgac
    16261 tgtgcctccc aatggcgcgg cgaacacgac agacaacttg ctacaaccac cgcaatcatt
    16321 cggaaagccg cgcagcgtgg aagaccgctg tcaggtgacc gccatctaca cccggtcagc
    16381 gtagtgagag cctttgcagc cacgccgagt ctgcgccgat gtgcttgcgc ttccgaaccg
    16441 ccgaacgtac cgacgccccg ctcaataacc ccttcataat caatggaatt catgattcgt
    16501 tggagtctcc gaaatctctg cctaggcaga gctggatagc ttctttgcga atgccctgtt
    16561 gaagctcggt cggccgggta catatggcgg gatcggtcgg tagccggccg acgggtagag
    16621 gtgcagggcg gggcggttgt aggaaccggt ctccaaacgc acctcccgga cgccgtgtgc
    16681 gctggcgtgc tgttcgagtt cggcaaggat ccggtgcccc agcccgcggc ctcgatgggc
    16741 aggggccaca tacatcttgc ggatttcggc gatgctgtcg cacgagagat atgcgcgcag
    16801 tccgccgcag gcgatcgcgt ccccggtgtt ggtgtaggcg acgaggaaga cccctgtcgg
    16861 aggctcgtac tgggcggcat tgtccaggcc cggcggatcg acgaacccca ccatctcctg
    16921 tctctcagcg gcataggcgg ccagtagtgc tgcggcgtca gggtgatcga actcgcgggc
    16981 cgcgatcggg gtatcggatg cgccgggtga gcggaggacc tgggacatag ggatatcttc
    17041 cctcgcgcgc accggtagcg acttccctgg attacagtgc gccgaggatg tgctcgagct
    17101 cgggaaggaa ctcacacacc actcgagagc ggcgccgttg caacaggtct cggtgcaatc
    17161 ctcgcagttt ggtcacacac cgtccggatt ggacatcgcc cagcattgtc gtcgctcgtc
    17221 gtgcggcggc gactacgccg tcgaggtcgc cgagcatcag atggacctgg gcgagttggc
    17281 agccgtgcag caccgctgag cgctgatatc cgggatcgcg gtcgaggttt gcgcgcgggg
    17341 tgagcagatc ggatgcttgc ctgagcagcg gccggcggtg gacctcagta cgccgggcca
    17401 attggacgag gctgtatccc gcctcggcgg caagctggtc gggagtgagg tagtacagat
    17461 agggctcggt atggtcgcgg cgcgcggtat cgagcaggtg ctgcgcccgg tcactggcgg
    17521 cgcggaaagc cgcgatatct cccgccgcag cgtgcgcgct tgcctgacgc cccgccagcc
    17581 gtgccttgag cagcaagctg gaggtgggaa gggtagccgc agcctcggtg atcgcgaccg
    17641 aatcgtgccc ggcgtcgact tcggcggcga tataggcgag cattccggcc gcgttgatcg
    17701 cgcggtcgcc gtcgcgggcc gcgcgcgcga tgcgtatacc gagaacgagg tagcgctgag
    17761 cggtctcggt ggcacccgag tcgaaactca tccaaccggc gagctgggcg aggtcggcga
    17821 tggaggtcag cagcgaatcc tgcacggcgg gctcgtgact gccgctgcgc agcagatcga
    17881 tgacggtggc gagttcgcgc gagacgtaac ggagactcag tgcgccgccg ccctggcagt
    17941 cgtcgagctg gcgcagcgcg gtgacatgat cggcgatcaa tccggcctgc gaatgatgta
    18001 tccggtcgcg gccttggctg ccgccacgca gctcgatcgg gtcgcgtaaa cccgtgatcg
    18061 cggcggcggc cagatcggag ccgctgatcg gcgcgggccg gataccggcg gcgagctgat
    18121 ccagagaacg gatcgcctcg tcaatgcttc cctcactggg cagccgtgtg ccgcaagtga
    18181 tgcgttcggc gcgggtgtgt cccggccaga gctggctggc ggtgatgtag cgaccgagcc
    18241 ggtcaccgag cacggtggcg acgacttcgg caatgtcgcc gtgggggcaa tagcccgatc
    18301 gcacccacga gtaagcagcg gtcgcatcga tgcggtcgcc agggcggcca cgctgggcca
    18361 accacatgtt gaccgcgcgt gtcagatcgc gtggtcccca cccggcctcg ccgagcacgg
    18421 tacgcagcat catcgtctgc gcctccggag ccggattttc cagcggtgcg tcgtgcacgc
    18481 ttcgacgata gcggcaagtg cccggtagcc gatgcacgat cgcgcgtgtt cacgaacttc
    18541 acgcccccat tgccaatgtt cacaacgttc acgggtggcg gtgcttcccc taccccgcag
    18601 cttgggagtt aactcggatg cagcgggaag gcttccgcat atcccgaaaa cacaacggtc
    18661 ccagaggatt tcgctgcatc gagacgggcc gtttcgcggg gcggcgtatt cgcctccact
    18721 ccactgcatc ctacggattg gacgtactga tgatctccga tctgcgagta gctcgaatgg
    18781 caattcgttt ggctcacaat cacatcggcg aggttcgtat tccggcgatg tcaagccgcc
    18841 aggaacgcgc ccacggagca aaactccggc cggatcgcaa cgacgactgc cgcgtcgaca
    18901 tcaccgggtt cagcaacgct gctgaagctg gtgcggtgta tgcgagtcat atcgaccatg
    18961 gcccgcattg cttgctctgg ttggccgcgc tggcctatga gtcctgcggg ctgcaggacg
    19021 agtaggtcgg tgacggccgg gcatgtgctc gtcgcgttcg gtctggcggt gttgctcgcc
    19081 gagctgctgg ttgccgtgct cggctgtggt ggcaccacgg acgtggatca ccctgctccg
    19141 gtcggtgggt tcacgatcgc ggaggcgcat cgggcgactc agcagcatcg cgagtgttcg
    19201 ccgcgggagt gcgagtgcgt gcgggaggcg tggcgcactc tcgttctggc gggtcgctgc
    19261 gctccgacgg gcgagctgca tcgcatgttg tacggctgaa cgccggcgct gttggtcgat
    19321 tcccgaaatc tgttgcccac caacattatc ggatgggaga ttgccgtggt agttcctcgt
    19381 gacgacctgg tggcaccggg tgtgccgctg accggtctgg acgcgatcga tgccgcgttc
    19441 gccgagcaga tgcggctact gcgggcggtt ttcgaggtac gtcgcacggt cgcggatacc
    19501 ggtgacggtg tgttcgaggt cggtggtgcc gtgtccgtag tggattctca cggtgccgac
    19561 accgccggct ggtgcgagtt ctatcgggag acctgtcgat tcgacgtcgc ggtacgcccg
    19621 gaggtcggtc tgatttatgt gacggcgggc gcacggatcg ggtcggtcag gatgcctgcc
    19681 gagctcggcg cactggtcga ggcccgcctg ggagacgcgg gggtacggct ggggcctgtc
    19741 atcgggttgc gtgagcggca gtgggtgctg ctggtggaac ccgatattcc cgaccggatc
    19801 gacatctacg ccgggatgtt ccggcacgcg gtgtcgatcg cccgtgcggg cgcgcagatc
    19861 gcgcttccca ccttcggcac cggccgtact cggctgcgga cctggttgcg ccaacctcgc
    19921 gacgcgtacc tgccggcggg gacagcggtc ctcgcggcgg tcaccgcctg ctttccggtc
    19981 cggaccgccc cgccgtgaag acgcattgaa taggcgaccc tccgcacacg attggacgtg
    20041 tctggtgtgg agggcgacga aaccccctgg gctggtgaag gtcgacacgc catccctcgt
    20101 cagcaccagc ccgggggcga tcgtctatag cttgcctcac ctggtggacc tcaaggtgcc
    20161 gcacaacaac gaggcactgg gtgaggtagg agggaagccc cctggcttcc atgattttcg
    20221 ggagacactc cccagggggc gacccgcacc accttcctct cctctgacga cgggcagggc
    20281 cagcctggcg cggggagagg agcaagaggg aagttcctgg gcatcgaatc attcgcccca
    20341 ccggtagagc cctggccaga attccgggcg cccacaggga acttcctcac cgaggacttc
    20401 cttgttcggt ccggtaggcg tcggacaagg gaggcgtgag accccctggg caaggcggat
    20461 cggcgacaaa tcgccccgag taaccacttc acgctggccg gatttgccca aggggtcgac
    20521 ccgcgcagtg ccgcgctgga gtcccacacg aaagctctgt gcagtaccgg aagcaggcag
    20581 gtgccccgac gctcgtatcg cgcgtggcgc tcattcgtac gagcgttccc cgacgacacc
    20641 ggcggttggg acgtggatcc gcacatccgc caccgtcgag accggctcgg cgggtatcga
    20701 aacagattga gagacaccag tagtgaacga tcagaccttg acggcgctcc actcctgggc
    20761 gcgcgggatc attctcgggt tggcggtgat caccgtgatc gacgcggtcc aggatctcgc
    20821 cgactggctc gcgggaaggg ccgggcagcc gggccgcaac tccgactcga tcggggaccg
    20881 gtaggggccg cgaaccgaca cctacgtgca ccagttgcac gccagctggt cccacaccag
    20941 ccgcttgatg accgagtggg cggatttcat cctctcgtgc tctaccggca ggcgccccgc
    21001 attggccgcc cgcaggttct tcgccgcagc ccttcgagcc accgaacact acacaacccg
    21061 ccgttgcagg aaccggcgct gttacacatt cacccggcgc gggctcgtca gccccgtatc
    21121 gaaacagatc agtacacaac aactttgact catccggggc tctgcgtcgg tcgagtcgtc
    21181 ccggtttcga acgcgcaacc ccggcccggc gtaccagcga aacatctccc ccagactctc
    21241 gttgaaagcg acccatgaca ccgctgtcct cggtatacaa gtcgactctt ctgcgtcgtc
    21301 atctcggtat ctatttgcgg gagcgtcgcg atagcgtccg ctggcggtcg cttgccgtga
    21361 ccgctgtgca gacctcggtc acgcagtcgg ccata
//
