LOCUS       NZ_QZFU01000013        23683 bp    DNA     linear   CON 08-AUG-2024
DEFINITION  Nocardia panacis strain YIM PH 21724 NODE_14, whole genome shotgun
            sequence.
ACCESSION   NZ_QZFU01000013
VERSION     NZ_QZFU01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Nocardia panacis
  ORGANISM  Nocardia panacis
            Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
            Nocardiaceae; Nocardia.
REFERENCE   1  (bases 1 to 244691)
  AUTHORS   Miao,C.
  TITLE     YIM PH21274 draft genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 244691)
  AUTHORS   Miao,C.
  TITLE     Direct Submission
  JOURNAL   Submitted (19-SEP-2018) Yunnan University, Yunnan Institute of
            Microbiology, 121, Kunming 650091, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 29.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003598715.1-RS_2024_08_08
            Annotation Date                   :: 08/08/2024 03:06:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,880
            CDSs (total)                      :: 6,804
            Genes (coding)                    :: 6,707
            CDSs (with protein)               :: 6,707
            Genes (RNA)                       :: 76
            rRNAs                             :: 4, 5, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2, 4, 3 (5S, 16S, 23S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 97
            CDSs (without protein)            :: 97
            Pseudo Genes (ambiguous residues) :: 0 of 97
            Pseudo Genes (frameshifted)       :: 32 of 97
            Pseudo Genes (incomplete)         :: 82 of 97
            Pseudo Genes (internal stop)      :: 7 of 97
            Pseudo Genes (multiple problems)  :: 22 of 97
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:26:29
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 38206
            Orig. end                         :: 61889
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QZFU01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23683
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="1"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..23683
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23683
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13683](+)"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13683
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     misc_feature    500..514
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.9"
                     /tool="antismash"
     misc_feature    558..567
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            complement(766..1635)
                     /locus_tag="D5S18_RS05135"
                     /old_locus_tag="D5S18_05140"
     CDS             complement(766..1635)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009079440.1"
                     /locus_tag="D5S18_RS05135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05140"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_120038559.1"
                     /transl_table=11
                     /translation="MGNNDLGDFLRARRAGLTPEEIGLPVEFGGGRRVAGLRRGEVAQL
                     AGVSTEYYTRLEQGRARQPSEQVLRALCDALRFDDIERRHLFALAGAASGRAGHAEHSS
                     RLRPALRQVLDSMDLASAFVSDRNLTVVGGNALWALLFPDVAAMPRRERSMARWTLLDP
                     SARLVWCDWERVARDYVHGLRRAAADQPRNQHIANLIGELMMRSPEFPAWWSEHRVQER
                     STGLKRLHHPVVGDLELQYEIFTSVADPGQSLVVYTAPSGSPSQERLRLLASWGSEPAA
                     IRDTAAES"
     gene            1749..2471
                     /locus_tag="D5S18_RS05140"
                     /old_locus_tag="D5S18_05145"
     CDS             1749..2471
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014985474.1"
                     /locus_tag="D5S18_RS05140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05145"
                     /product="FadR/GntR family transcriptional regulator"
                     /protein_id="WP_120038561.1"
                     /transl_table=11
                     /translation="MEGLRQPRRASTLTAQVADQLRDQLASGRWPVGGRIPGEQELTEL
                     LGVSRNTVREALRSLIHLGLLEARVGDGTYVRVSSELEAVLLRRAATARASDVAELRAV
                     LEEHAAAVAAERRTEADVDRLRELLDELREHNSGGVMTELAAADGAFHLAIVRAGGNAL
                     LTELYEHMGAALTSMVSELPWDADIAAEHDRWHGALVDAIAARDAVAARHAAVMLVRLT
                     GAHAIAERTDSTTPERTA"
     gene            2468..3682
                     /locus_tag="D5S18_RS05145"
                     /old_locus_tag="D5S18_05150"
     CDS             2468..3682
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014987357.1"
                     /locus_tag="D5S18_RS05145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05150"
                     /product="MFS transporter"
                     /protein_id="WP_120038563.1"
                     /transl_table=11
                     /translation="MTIRTAAPEDTKAPPALLLMAGIVLVAANLRAALTGVGPLLPEIE
                     RSTGLSGIWSGLLGALPLLTFAATSPFVGRTAHRFGSARVLGNSLLILATGLLVRSLPG
                     VFFLFAGTFVVAAAIAYGNVLLPAVIKSSVPESRIGQVTAGYVTAMGLVAALSSGISVP
                     MAAYLPGAWRTALGCWIVLAALAFVVWLPQYRRGRRTESAAPAAREPIPWRSGLAWQVS
                     VFMGLQSLAFYTIIAWLPSILHDRGVGAASAGWQLFLFQIAGLVSSIVLPFLTRRWRDQ
                     RIIAATASLLAALGFALLILAPGLAVVSCVLIGLGGGACLVLALSFQSQRAANPAQAAA
                     LAAMAQSVGYLVAAIGPLLLGALHDGTAGWRIPLLLLVALALVQAAVGSRAGRDTRLST
                     RVDPI"
     gene            complement(3798..4508)
                     /locus_tag="D5S18_RS05150"
                     /old_locus_tag="D5S18_05155"
     CDS             complement(3798..4508)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006063976.1"
                     /locus_tag="D5S18_RS05150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05155"
                     /product="AAA family ATPase"
                     /protein_id="WP_239003551.1"
                     /transl_table=11
                     /translation="MRHLTRAGGIEIPAGVTFLVGENGSGKSTLVEAVAVAAGLNAEGG
                     SQNFRFATRATESKLGEHLTLAWGISKPRTRFFVRAESYYNVATETERLGPEQLRAMGG
                     VSPHARSHGESFVDLMRHRFLANGLYLLDEPESALSPQGCMAVLARLAELVRQNCQILV
                     ATHSPILLALPGATILEIRETGEISEVTYDEAMPVRLTRSFLADPDRYLRYLTEPEQHE
                     GAQDIPPGRATFGR"
     gene            complement(4604..5371)
                     /locus_tag="D5S18_RS05155"
                     /old_locus_tag="D5S18_05160"
     CDS             complement(4604..5371)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023812.4"
                     /locus_tag="D5S18_RS05155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05160"
                     /product="DUF3658 domain-containing protein"
                     /protein_id="WP_120038568.1"
                     /transl_table=11
                     /translation="MLTVHLAPNLSSAKSIRAALDAADAVGSEVVMGRDDLSCGPLDCG
                     DRRAWWNATFTGDMGMRQAALWESAEPGPRRSVGPAARTIVWVSKHSAQEYADYLFLTT
                     RPRDHRLHVIDVTAGSRGPANESIAAVASLTPAEISTYLGSERALDGAERTELAQKWAR
                     LRSENAPLRVVSAASELVSAPVDYFDEALQNHVSVAPTPMPAVIAAVMAEHRFQTGDYV
                     LQRRLIDLVAAGVVAAEGDPRTARSCRIRQAEQ"
     gene            complement(5444..5746)
                     /locus_tag="D5S18_RS05160"
                     /old_locus_tag="D5S18_05165"
     CDS             complement(5444..5746)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS05160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_05165"
                     /product="hypothetical protein"
                     /protein_id="WP_120038570.1"
                     /transl_table=11
                     /translation="MLRSSFFRRGAGLIVGVFALGLVTGTGVSDAVTFVDVCVVRQDIQ
                     FRQVSDDDWVPWDRVLGVYNSEQECINVGQALADSTKGRYHCQMIRNGGAWALFY"
     misc_feature    5872..5887
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     gene            complement(5953..6780)
                     /locus_tag="D5S18_RS05165"
                     /old_locus_tag="D5S18_05170"
     CDS             complement(5953..6780)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046559.1"
                     /locus_tag="D5S18_RS05165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05170"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_120038572.1"
                     /transl_table=11
                     /translation="MSDTPGVLAGRVAVVTGASRGIGKGIALELGAAGATVYLTGRTVK
                     AKQLPGTVAGAAAEVDALGGVGVPVICDHLYSSGVVKLFERVREEQGRLDILVNNVYDS
                     PGSARWLGRKFWEIPPAAWDAGFDIGVRSHYVAAFYAAPLLIEARGLIVNISSPGAVRT
                     MHNAVYGVGKAALDRMTAEMAHDLADTATAVSLWPGIVNTELLQLIPPGPDGRRLLTIP
                     GEPTIDLATAETPRFTGRAVVALAADPDRNTRTGKAWKVADLAEFYGFSDLPD"
     gene            complement(6785..7093)
                     /locus_tag="D5S18_RS34345"
     CDS             complement(6785..7093)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS34345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_147403849.1"
                     /transl_table=11
                     /translation="MNRRVLLAVTAGGALFLVPWTLWLAVQLPNGYTTYEWRLAWVGFD
                     VLLLTGLACSAWLGLRRRRAAVPVLNATAALLGCRVSVSPHPSRGKSRTRSHFTVES"
     misc_feature    complement(7049..7051)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7120..8463)
                     /locus_tag="D5S18_RS05170"
                     /old_locus_tag="D5S18_05175"
     CDS             complement(7120..8463)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS05170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_05175"
                     /product="hypothetical protein"
                     /protein_id="WP_147403850.1"
                     /transl_table=11
                     /translation="MTPPSDAPRTHAGSVAEQTDPRGLLRLRLAAAGGPAVHRMVAPGL
                     VEVLTLAPLGRAVTPELLAEWEIGVEEALASAEANSGAESLELGWEGRGETDLAVLTGS
                     EFAGAHIRRLEHYPVIGQHGALFVAAGAGELYAHPLCGPDSEVVLDALGTIACSAAITS
                     SVFWWQDRVIRLAATTATRADGSVEVRPTPELRSVLDGLTATHEFALLPADIDGALEAL
                     EIYSRLRTDPGRPDPALRALSIDLDPAYGLTAGAGGAILHARGHDRAHHLLAALNLTKD
                     RDLAVLDIATGCLYNPRERVEVEVTMPDHTLPYLTPALLADLITAAADPNDPDLTLTRA
                     GDRIRAHRHEYVYQLETRTGTECSRVYTVLPVVVREVLWAWACEDPDWKTAVGWRKVAP
                     GAPGVESARGLEILQDELAAPTSRLTVEGLALLDQFLGLRDRALPAGE"
     gene            8593..9444
                     /locus_tag="D5S18_RS05175"
                     /old_locus_tag="D5S18_05180"
     CDS             8593..9444
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011782952.1"
                     /locus_tag="D5S18_RS05175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05180"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_120038576.1"
                     /transl_table=11
                     /translation="MDEADVPTDVSDTARWVAAYRAQESARPDALFRDPLADKLAGEQG
                     RAMAAAAERTLSGGWPIVVRTKLIDDLIRDCLAQGCDRVLNLAAGFDTRPYRLDLPPEL
                     LWVEADLPAMTHEKEAALAGATPKCALLRRAVDLADEQARQAFLDEALDAHEPANKPAT
                     KALVLTEGLLSYLEPDTVAGLATVLDRPEIAWWIADIALGLAKMKLSMFRNAPLRFDPP
                     NGVAFFEELGWRITDMEPIFINARKLRRMPWYMRPFTYLPQPNPRKPGRQVWSAVTRLQ
                     HE"
     aSDomain        10001..10300
                     /aSDomain="Goadsporin_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     goadsporin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_D5S18_RS05180_Goadsporin_CD_RRE.1"
                     /evalue="2.40E-32"
                     /identifier="RREFam013.1"
                     /label="D5S18_RS05180"
                     /locus_tag="D5S18_RS05180"
                     /protein_end="100"
                     /protein_start="0"
                     /score="102.0"
                     /tool="antismash"
                     /translation="MGSVLRFTRHLGVQTVAGDGVYVFSEGSRRTRLHGGLMERLAPFL
                     LTGRSRGDISAALANDFDSDRLDSALARLVDAGLVVECDPEVDPRAGGYWELCGL"
     gene            10001..12241
                     /locus_tag="D5S18_RS05180"
                     /old_locus_tag="D5S18_05185"
     CDS             10001..12241
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Goadsporin_CD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cyanobactin_D_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NHLP_CD_RRE"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="D5S18_RS05180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05185"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_120038578.1"
                     /sec_met_domain="Goadsporin_CD_RRE (E-value: 2.1e-31,
                     bitscore: 102.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="Cyanobactin_D_RRE (E-value: 1.1e-09,
                     bitscore: 32.2, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="NHLP_CD_RRE (E-value: 1.2e-15, bitscore:
                     51.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 3.6e-96, bitscore: 316.6,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 2e-80, bitscore:
                     264.3, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSVLRFTRHLGVQTVAGDGVYVFSEGSRRTRLHGGLMERLAPFL
                     LTGRSRGDISAALANDFDSDRLDSALARLVDAGLVVECDPEVDPRAGGYWELCGLDGDA
                     AVARLRDRTVDVVGIGQVIDAEFAAAAMALGLQVGPGSPDLRVVLTDDYLRPELADHNR
                     ARLTDGGAWMPAKPVGSTVWIGPVFEPGRTGCWRCLSTYLESNQLVRSYLRQRTDAAGP
                     PVAAEIGLPATRQLAAHMAALHAAQWLTGAEVGADRPSAPHTVMFTFDTIGWQWSRHVV
                     RARPQCPECGDPDLQRRLQWDPVQLVSRPKIFTTDGGHRAKTPEALLAEYGSLISPITG
                     PVTELVPSSAADDLFAYRAGANAAMSMTDISALHAGLRQSAGGKGMTDTQAKASALAEA
                     IERFSGVYCGDEATVTARMDELDGAAIHPNSLQLYSDRQFAERAAWNAKKIPYQRVCDP
                     FDPDDRIEWTPVWSLTHNATRYLPTANLFYDYPQQAGRFAFADSNGNAAGGCLEDAVLQ
                     GFLELVERDSVALWWYNRIQRPGIDLSGFDEPYFQRWQHRYRSLGREAWALDLTSDLGI
                     PAVVALSRRIGAPREDILMGFGAHFDVKIAISRALTESNQFLGYDSTPVEDLTPELREW
                     YTEATLDNQPYLVPADEPSRTSADYHDPSTDDLAEDVRLAQRIVENSGLEMLVLDQTRP
                     DIGLPVVKVIVPGLRHFWTRYAPGRLYEVPVRMGWLPEPTPESELNPIGMFL"
     aSDomain        10004..10243
                     /aSDomain="Cyanobactin_D_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing D protein in a cyanobactin
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_D5S18_RS05180_Cyanobactin_D_RRE.1"
                     /evalue="1.30E-10"
                     /identifier="RREFam007.1"
                     /label="D5S18_RS05180"
                     /locus_tag="D5S18_RS05180"
                     /protein_end="81"
                     /protein_start="1"
                     /score="32.2"
                     /tool="antismash"
                     /translation="GSVLRFTRHLGVQTVAGDGVYVFSEGSRRTRLHGGLMERLAPFLL
                     TGRSRGDISAALANDFDSDRLDSALARLVDAGLVV"
     aSDomain        10007..10288
                     /aSDomain="NHLP_CD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing CD fusion protein in a
                     NHLP/Nif11 LAP cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_D5S18_RS05180_NHLP_CD_RRE.1"
                     /evalue="1.40E-16"
                     /identifier="RREFam015.1"
                     /label="D5S18_RS05180"
                     /locus_tag="D5S18_RS05180"
                     /protein_end="96"
                     /protein_start="2"
                     /score="51.3"
                     /tool="antismash"
                     /translation="SVLRFTRHLGVQTVAGDGVYVFSEGSRRTRLHGGLMERLAPFLLT
                     GRSRGDISAALANDFDSDRLDSALARLVDAGLVVECDPEVDPRAGGYWE"
     gene            12238..13683
                     /locus_tag="D5S18_RS05185"
                     /old_locus_tag="D5S18_05190"
     CDS             12238..13683
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: goadsporin_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="D5S18_RS05185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05190"
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="WP_203236596.1"
                     /sec_met_domain="goadsporin_like (E-value: 9.1e-173,
                     bitscore: 569.3, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PF00881 (E-value: 4.7e-13, bitscore: 43.5,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPPTAIADITMIDNVMRLRTGVEIEHDADLLTLTGAHGSFTLRN
                     MSDGLVSAMRRLHRAVPLSELNSSLTDHERHQLQRILARLNKLLARCVVIDDTELMSLE
                     PTAPDATYHPSPPRPGARLRLSKFSFARSRDDLLVLESPLAHHRALLPHPAAGAVVAAL
                     GTTSGAIELADAAGLPLPVVHNLLAHLIGANLVEVDDPESGRFASETDNALRQWDFHDL
                     LFHSRSRSGRTDDPHGGVFSYLGDIPPHPAIKPPPNGPAVQLPRPSWRDIADRDPQLST
                     VMEQRVSIREHATLPIDLDQLGEFLYRVARVRTRSWPDGAHYETTTRPYPGGGAAYELE
                     FYLAVHRCDGLRQGIYYYDPLEHRLILINDNESDCRTILDDASAATAFQGNPDIAITIT
                     SRFGRLSWKYRGIAYALTLRHVGVLYQSMYLVATAMGLAPCAIGSGNSDAAGRILRLNY
                     TEESPVGEFVLGSRPHPHAPDTD"
     gene            complement(13806..15401)
                     /locus_tag="D5S18_RS05190"
                     /old_locus_tag="D5S18_05195"
     CDS             complement(13806..15401)
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013739.4"
                     /locus_tag="D5S18_RS05190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05195"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_158607801.1"
                     /transl_table=11
                     /translation="MVQRTVTEYMVAERLGIPVDEVRAPIFDRRTLLKAGVGAAVFAGL
                     AGRQPAVAQSLGPDTPRIAIIGAGIAGLNAALTLADAGIAATVYEARGRVGGRMFSERE
                     YWDGGQVSEYGGEGVDSDHHTIRNLCSRFGIPLVDTLSAAPAGSSPVLYFDGGYVPRDK
                     FIADFEPVFRALQVDAAACPATPTWNSATPAGIALSTMSLTEWIATRVPGGYSNWIARL
                     FDDAYVVEYGMPTADQTALNLVSMMKTQKSLDDPRAWGNSDEQYKISGGSQRLPRAIAE
                     ALPDGAIRYEWRLEAIVRDSDGGQTLIFDDAGTRRTVRADHTILAVPVGVLKHIDYSAA
                     GFDPRMTGVIDALPMSTSTKLNMQFTSRPWVGRGQWPGVSNGASFTDVGYQAIWDATAG
                     QPGKQGIAIQYGGGLDARGFAPPSAFPTAADLAVRTRVGTVLAQFERVVPGIGTLWNGR
                     ATLSAWHADPLANGAYSAMPTNYSHRFFGYEGARQGNIHFAGEHTSSESQGYMNGGAES
                     GARAAREILSDLGR"
     gene            complement(15604..16068)
                     /locus_tag="D5S18_RS05195"
                     /old_locus_tag="D5S18_05200"
     CDS             complement(15604..16068)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019930881.1"
                     /locus_tag="D5S18_RS05195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05200"
                     /product="VOC family protein"
                     /protein_id="WP_120038582.1"
                     /transl_table=11
                     /translation="MQRVSTFLWFDGRAEEAADHYTGAFADAKILDTQRALDGGVSTVT
                     FELAGQRYIAYNGGPELSFTGAAISPHVECDTQDEIDTLWAALTDGGREGPGGSLTDRF
                     GVTWQILPTTLRKLLDNSEPEAAGRVLTALHAMTRIDIQILIDAHDQPCL"
     gene            complement(16092..17324)
                     /locus_tag="D5S18_RS05200"
                     /old_locus_tag="D5S18_05205"
     CDS             complement(16092..17324)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1087: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="D5S18_RS05200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05205"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_120038584.1"
                     /transl_table=11
                     /translation="MRNRSILVSGAGIAGPTLAYWLHRSGFRVTVVERAHAPRSGGQAV
                     DIRGTARQVAERMGIVAEVRGAHTGARGMAFVDRHGKRVATLSTAVYGDSGGPIAEMAI
                     RRTDLARILYRATRDDVEYVFGDSITAVEQDDDGVRVEFETGGTRRFDLLVGADGVHST
                     VRRLVFGPPERYLRDLGCYIALFTTTTTVDLDGWQLMYTTPAGAGRPGRTVGLGPQPTP
                     DAVLAGFFLRSPVLRYDRRDIDEQKRIVVRAFETDAWETPRILSTIRDSPDFYFDRVGQ
                     VHVDTWSRHRTVLLGDAAYCASPMSGIGTSLAMVGAYILAGELAAAEGDPRHAFPAYQR
                     KMRDFAGRAQHFARGAGDSGLMPDSQAQLWLRNVSVRMMPFLPRRLIGHGMEKLANIVE
                     LDDYTTVKTEP"
     misc_feature    complement(17448..17464)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.11"
                     /tool="antismash"
     misc_feature    complement(17453..17469)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.6"
                     /tool="antismash"
     misc_feature    17489..17504
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            17520..18524
                     /locus_tag="D5S18_RS05205"
                     /old_locus_tag="D5S18_05210"
     CDS             17520..18524
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014906.4"
                     /locus_tag="D5S18_RS05205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05210"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_239003552.1"
                     /transl_table=11
                     /translation="MLGAQIGGRGLSSTQRTDPPYRAIAEEIRHRITTGELQPGDRVPS
                     VRRITQRWGVAIATATRVIATLRDEGLVETKVGSGTVVSTPGDREASEIPAAPPAPRAA
                     RTPHDAMNRRHILRAAIAIADVEGLDAVTMRRLAAHLGVGPMSLYRHVANKDELLTQMA
                     DEVFGEANLPEPGPHGWRAKLELIARLHWQLCRRHMWLPGAVSFTRPLLVPNMMAHTEW
                     TLRALDGLGLPIVTRFREALTLHALVATLALSLAEEAEAERNTGVTLDRWRAMQRTPTA
                     ELRSGGRFPLLAAVPEDTVADLDGLLEYSLARHLDGFAALVTERRTDHDAANN"
     gene            18711..19100
                     /locus_tag="D5S18_RS05210"
                     /old_locus_tag="D5S18_05215"
     CDS             18711..19100
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS05210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="D5S18_05215"
                     /product="hypothetical protein"
                     /protein_id="WP_147403851.1"
                     /transl_table=11
                     /translation="MLATPFAHAAPGDRVNCVPVPIASRLEVTCTNTAAEAATATMTAL
                     CSNLRILHEPEFPIAPADTVTFSQDCGAGATLLSWNASGETISERAQRLARERSDEQDK
                     QRKQREQSAEDDKHREQERKRRSEF"
     gene            complement(19184..20266)
                     /locus_tag="D5S18_RS35230"
     CDS             complement(19184..20266)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="D5S18_RS35230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_203236598.1"
                     /transl_table=11
                     /translation="MFRLDGEVGVSCSQIYVESAPGGTPPMHEAFAGQNSGLCGAAVPG
                     ALFLHTGLHTGDVGFTVEVRGQAPPLDPAWEDVVEVSFYPLSDQSFLVQWAGEDSWELD
                     LKEGLDYRVRYCAQGMDRAREKDVRLDDEPVLDRYLLQFWPAPPEPDRIVRQTSQDAAY
                     SHDWVRRQPDAEFRVRAIMAQRRAHLTPEGDESFRDAESPSPSADMAVISREADPGSVR
                     EQLTSLSSYPAALPWDWVAAFDTEHAPDHHIGYLQAFLEEIGERAFALGTVLASLESGP
                     DYYLAFVTPTEFEHLSRLLTAHRMNAESVRHGRWTPRASPEQIAISAWAKANAHRLGAG
                     QGVPITIIEAPEAAEPDRLT"
     misc_feature    20466..20479
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     misc_feature    complement(20519..20532)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.65"
                     /tool="antismash"
     gene            20526..21749
                     /gene="dinB"
                     /locus_tag="D5S18_RS05225"
                     /old_locus_tag="D5S18_05230"
     CDS             20526..21749
                     /EC_number="2.7.7.7"
                     /GO_function="GO:0003684 - damaged DNA binding [Evidence
                     IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="dinB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020105208.1"
                     /locus_tag="D5S18_RS05225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05230"
                     /product="DNA polymerase IV"
                     /protein_id="WP_120038590.1"
                     /transl_table=11
                     /translation="MFVSRDSERIATRAEASILHADLDSFYASVEQRDDPRLRGRPVIV
                     GGGVVLAASYEAKAFGVRTPMNGRLARRLCPQAIVVPPRMAAYAEASRKVFEVFRDTTP
                     VVEGISIDEAFLDVRGLRRIAGEPEMIARRLREQVRTEVGLPISVGIARTKFLAKVASA
                     VAKPDGLRLVPAGGELEFLHPLPVERLWGVGEVTARTLHEHGITKVGQLAELGESPLRA
                     LLGPGAARHLYALAWARDPRRVETGRRRRSIGAQRALGVRHREPDEIEAYLHGLIDRLG
                     RRLRAADRLSRTVVLRLRFADFARATRSHTLAEATDHTPTLLGAARRLLADAMPLIDDR
                     GLTLIGLSLTNLADADPFQLSLPFEERAENTLDTTLDRLRERFGSAAVTRAALLGRGEG
                     LSVPLLPD"
     misc_feature    21411..21413
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            21847..22197
                     /locus_tag="D5S18_RS05230"
                     /old_locus_tag="D5S18_05235"
     CDS             21847..22197
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014351459.1"
                     /locus_tag="D5S18_RS05230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05235"
                     /product="PLD nuclease N-terminal domain-containing
                     protein"
                     /protein_id="WP_120038828.1"
                     /transl_table=11
                     /translation="MPYAVLGLITLALWVYCLIDIITCPDAGIRHLPKMGWLIVVILIP
                     TVGALLWLFVGRPVREIAPRSNTRFTEYDRPGRHIAQNPDDDAEFLRGLRERAEQQRRE
                     ARRQQEQRGEEQ"
     gene            22324..23109
                     /locus_tag="D5S18_RS05235"
                     /old_locus_tag="D5S18_05240"
     CDS             22324..23109
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019046482.1"
                     /locus_tag="D5S18_RS05235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="D5S18_05240"
                     /product="aldose 1-epimerase"
                     /protein_id="WP_120038592.1"
                     /transl_table=11
                     /translation="MTEQRTTLRAGDAELTVDPANGGRLTSLRVRDHELLRQGERFGCF
                     PMVPWCGRIALGRFEFDGRAYQMPINSPPHAIHGTGRNTAWTTLETTDRTAAFGYDLTD
                     PWPFRGRVTQSVALAPDSLTLTMRVDSAAESFPAQAGWHPWFNRELAGGDPVRIDFTPG
                     WQEERGPDHLPTGARVAPGPGPWDDCFGMPGGVEVVLTWPGTLALRISSPTEWVVVYDE
                     QEAAVCVEPESGPPNGLNTLPRMVAPSDPLEITTTWSWR"
ORIGIN
        1 gcgtcgccgg cgcgatccgg atcaccgatt cctttccccg cgagggcctg gcggcgggtc
       61 cggatcgggt cgaacagcgt gtcgtagtcg gcgatgctgc gtggtgcgcg gaccagtgac
      121 ctaccggccc aatcggtttt gaacgcgccg ggcgccaccg cggtcacccg cacaccgaac
      181 tggtcgacct cttgggcgag cgtgtcggtg atgccttcca gtgcgtgttt gctgccttcg
      241 tagaacgcca ggccggggaa ggtggtcagc ccgcccatcg aggtgatgac gaagatgtgg
      301 ccgccgcgtc gctcccgcat accgggcagg accgctttca ccgtcgccac cgtgccgaag
      361 acgttgacct cgaactggcg gcgcagatca tccatcgacg attcctcgaa ggtgccctcg
      421 agcccgtaac ccgcgttggc cacgagcact tcgatcggac ccagttccgc ttccacggcc
      481 cgcaccgcgg gttcgatccg gttcgcatcg gacaggtcga gcaggaaggc gtgggcgcgg
      541 tcggtgtcca gttcccggaa ggcggccgcg tgctcctcgg tgcgcacggt gcccgcgacc
      601 cgatgcccgg ccgccagggc gcgtcgggcg atggccagtc cgagtccggt gctgacgccg
      661 gtgatcagga atgtcttgct cacaacgggt ttcctttcga tgacgtgcgt gggcacggcg
      721 gtatcgaccc cacgggcatg gcggggtcgg tgattcgggc ggtgctcagg attcggcggc
      781 agtgtcccgg atagccgcgg gttcactacc ccaactggcc agcagtcgca gccgctcctg
      841 ggacggcgag ccggacggcg cggtgtagac cacgagcgat tggcccggat cggcgaccga
      901 ggtgaagatc tcgtactgca actccaggtc acccacgaca gggtggtgca ggcgtttgag
      961 tccggtgctg cgttcctgga cgcgatgttc cgaccaccac gccgggaatt cgggtgagcg
     1021 catcatcaac tcgccgatca ggttggcgat gtgctggttg cgcggctggt cggcggcggc
     1081 ccgccgcaat ccgtgcacat agtcgcgggc gacgcgttcc cagtcgcacc acaccaggcg
     1141 ggcactcgga tccagcagcg tccagcgcgc catgctgcgt tcccggcgcg gcatggcggc
     1201 cacatcggga aacagcaacg cccacaacgc gtttccgccg acgacggtga ggttccggtc
     1261 gctgacgaaa gcagaagcca gatccatcga atccagcacc tgccgcagcg ccggtcgcaa
     1321 ccgtgacgaa tgctcggcgt ggcccgcgcg gccggacgcg gcgcccgcga gggcgaacag
     1381 atgccgccgc tcgatgtcat cgaaccgcaa ggcgtcgcag agggcacgca gcacctgttc
     1441 cgacggctgc cgggcgcggc cttgttccag gcgggtgtag tactcggtgc tcaccccggc
     1501 cagctgcgct acttcaccgc gccgcaggcc cgcgacccgg cgaccgccac cgaactcgac
     1561 cggtagaccg atctcctccg gcgtgaggcc ggcacggcga gcccgcagga aatcgcccaa
     1621 gtcgttgttg cccatgcccc aagtttgctg tccacccaac cgatcaccaa gggggtagcc
     1681 ggccctgcca gtactacgca ccagagctaa atatgcttta atccaaatgt ccaacatttg
     1741 gaggtttcat ggagggattg cgtcagccgc ggcgtgcatc gacgctgacg gctcaggtcg
     1801 cggatcaact gcgggatcaa ctcgcgtcgg ggcgatggcc ggtgggcggt cggattcccg
     1861 gcgagcagga actcaccgaa ctgctcgggg tcagccggaa caccgtgcgc gaagccctgc
     1921 ggtcactgat ccatctgggt ctgctcgagg cacgcgtcgg agacggaacg tatgtgcggg
     1981 tcagcagcga gttggaggcc gtgctgctgc gccgggcggc cacggcccgc gcgtcggacg
     2041 tggcggaact gcgggccgta ctcgaagagc acgccgccgc cgtcgcggcc gagcggcgga
     2101 ccgaggcgga cgtcgatcga ctgcgcgaac tactggacga actccgggag cacaacagcg
     2161 gcggcgtcat gaccgagctc gcggcggccg acggcgcgtt ccatctcgcg atcgtccggg
     2221 cgggcgggaa cgcactgctc accgaactgt acgagcacat gggcgccgcg ctcacatcga
     2281 tggtgtccga attgccgtgg gacgccgata tcgccgccga acacgaccgg tggcacggcg
     2341 ccctggtcga tgccatcgcc gcccgcgacg cggtcgccgc acgacacgcc gcggtgatgc
     2401 tcgtacggtt gacgggcgcg cacgcgatcg ccgaaagaac cgacagcaca acgccggagc
     2461 gcacagcatg accattcgaa ccgccgcccc cgaggatacg aaggcgcccc ccgccttgtt
     2521 gctgatggcg ggcatcgtgc tcgtcgcggc gaatctgcgt gccgcactga ccggtgtcgg
     2581 cccactgctc ccggagatcg agcgatccac cggcttgtcc gggatctgga gcgggttgct
     2641 cggcgcgctg ccgctgctga ccttcgccgc gacctcaccg ttcgtcggcc ggaccgccca
     2701 ccgattcgga tccgcacgcg tactgggcaa ttcgctgctc atcctcgcga caggactgct
     2761 ggtgcgttcg ctgcccggcg tgttcttcct gttcgcaggc actttcgtgg tcgcggcggc
     2821 catcgcctac gggaatgtgt tgctaccggc ggtgatcaaa agcagtgtgc ccgagtcgcg
     2881 gatcggccag gtgactgcgg gctacgtcac cgccatgggt ctggtcgccg ccctttcctc
     2941 ggggatatcg gtgccgatgg ccgcgtacct gcccggcgca tggcgaaccg cgctgggctg
     3001 ctggattgtg ttggccgcgt tggcctttgt ggtctggttg ccgcaatacc ggcggggccg
     3061 tcgcaccgaa tccgccgccc ccgcggcgcg ggaaccgatc ccgtggcgat ccggactcgc
     3121 ctggcaggtc agcgttttca tgggcctgca atccctcgcc ttctacacga tcatcgcgtg
     3181 gctgcccagc atcctgcacg accgcggcgt gggtgcggcg tccgccggat ggcagctgtt
     3241 cctcttccag atcgcgggcc tggtttccag catcgtgctc ccattcctca cccgcaggtg
     3301 gcgcgatcag cggatcatcg ccgcaaccgc ctcactgctc gccgctctgg gcttcgcgct
     3361 gctgatcctc gcccccggac tcgccgtggt gtcctgcgtg ctgatcggac tcggcggcgg
     3421 cgcctgcctg gtcctggcat tgagctttca aagccagcga gcggcgaatc cggcacaggc
     3481 ggcggcgctc gccgcgatgg cccaatcggt cggctacctt gtcgccgcca tcggaccgct
     3541 gctgctcggc gcgctccacg acggcaccgc cggatggcgg atcccgctgc tgctgctcgt
     3601 cgcactggca ctcgttcaag ccgccgtcgg ctcccgcgcc ggccgcgaca cccgactgag
     3661 cacgcgggtg gatccgatct aatgctgcgg gcggacgtgt ggtctgcgtg gacgagctcg
     3721 gccgctcaac ctccaactcc ggccgcgacc cgtccgcggc tggttcccga gacggtggct
     3781 cgtagtcggc attcggacta ccttccgaag gttgcccgac caggtgggat gtcctgcgcg
     3841 ccctcatgtt gttcgggttc ggtgaggtag cgcagatacc tgtccgggtc ggcaaggaaa
     3901 cttcgggtca gccgcaccgg cattgcctcg tcgtaggtga cttcgctgat ctcgccggtt
     3961 tctcggatct cgaggattgt ggcaccgggc agtgccagca ggatcggcga gtgagtcgcg
     4021 acgagtatct ggcaattctg acgtaccagt tcggccagtc gggcgagcac agccatgcat
     4081 ccctgaggag aaagggccga ttcgggctcg tcgagcaggt agagaccatt ggcgaggaac
     4141 cggtgacgca tcagatcgac gaacgattca ccgtgcgaac gggcgtgtgg cgacaccccg
     4201 cccatggctc gtagctgctc ggggccaagt cgttcggttt cggtcgcgac gttgtagtag
     4261 gactcggccc gcacgaagaa cctagtgcgg ggtttggaga ttccccacgc cagagtgagg
     4321 tgttcaccca gtttcgattc cgtcgcgcgg gtcgcgaagc ggaagttctg tgatcctccc
     4381 tccgcgttca gcccggccgc gacggcgacg gcctcgacga gggtggattt gccggagccg
     4441 ttctcgccaa ccaggaacgt caccccggcg gggatctcga tgcccccggc gcgcgtgagg
     4501 tgccgcacga taggcaggtc gaaggggtag cggtcggtgt cgggggacgt ggctcggatc
     4561 ctgcgcagaa acctcgccgg ggcggatgag cgtggagggt atgtcactgc tcggcctgcc
     4621 gtatccggca cgaccgcgct gtgcgggggt cgccctcggc cgcaaccact cctgcggcga
     4681 cgaggtcgat aagtcgacgt tgtagtacgt agtcgccggt ctggaatcgg tgctcggcca
     4741 tgaccgcagc gatcaccgca ggcatcggtg tgggagcgac ggacacatgg ttctggagtg
     4801 cctcgtcgaa gtagtcgaca ggcgcggaga ccagttccga tgccgccgac accactcgca
     4861 gcggagcgtt ctcgctgcgc aacctcgccc acttttgtgc cagttcggtg cgttcggcgc
     4921 catcgagggc gcgctccgac cccagatagg tgctgatctc ggcgggcgtc agcgaggcca
     4981 ccgcggcgat cgactcgttt gcggggcctc gactaccggc ggtgacgtcg atgacatgca
     5041 accggtggtc gcgaggccgc gtggtgagga acagatagtc ggcgtattcc tgggcgctgt
     5101 gcttgctcac ccagacgatc gttcgggcgg cgggaccgac agatcggcgt ggccccggct
     5161 ccgccgactc ccagagcgct gcctgtcgca tccccatgtc gccggtgaag gtcgcattcc
     5221 accatgcgcg tcggtcgccg cagtcgaggg ggccacagct gaggtcgtca cggcccatca
     5281 cgacctcgct cccaaccgca tcggcggcgt cgagggccgc acggatcgat ttcgccgacg
     5341 agagattggg agcgagatgc acggtgagca tgttccctat tgtgttccac tcggccgatc
     5401 cgagctcgca gcccgccgac cggacaccag ggtgactggg acgctagtag aaaagcgccc
     5461 aggccccgcc gttccggatc atctggcagt gataccgccc tttggtggaa tcggccagtg
     5521 cctgcccgac gttgatgcat tcctgttcgg agttgtacac cccgagcacc cgatcccaag
     5581 gcacccagtc atcgtcggag acctgccgga actgaatatc ctgccgcacg acgcagacgt
     5641 cgacgaacgt caccgcgtcc gaaacgccgg tgccggttac cagccccagc gcgaaaactc
     5701 cgacgatcag acccgcaccc cgtcgaaaga atgaactcct gagcatgaga ctccctctcg
     5761 tgcaaaggga ttgcgccacg ctcaccgctg agtgcggcgg ttcccccgtg atgggcgaag
     5821 acacttcccc gcccatctac ttggatgcac gagaacgcgg atcggttccc tgtcacgctg
     5881 aagtaaccgc accttcgccg cccgtgatca tgtcccgcgt acctcccggc acgaccgcga
     5941 caacctcttg attcagtccg gtaggtcgct gaagccgtag aattcggcca aatcggcgac
     6001 cttccaggcc tttccggtgc gggtgttgcg gtccgggtcg gcggcgaggg ctacaacggc
     6061 gcggccggtg aagcgggggg tttcggcggt ggcgaggtcg atggtgggtt cgccggggat
     6121 ggtgaggagg cggcgaccgt cggggccggg cgggatgagt tggaggagtt cggtattcac
     6181 gataccgggc cagagggaga ccgcagtggc ggtgtcggcc aggtcgtgcg ccatctcggc
     6241 ggtcatgcgg tcgagggcgg ccttgcccac gccgtacacg gcgttgtgca tggtgcggac
     6301 cgcgccgggt gaggagatgt tgacgatcag gccgcgggct tcgatcagca gtggggcggc
     6361 gtaaaaggct gccacgtaat gggatcggac gccgatatcg aatccggcgt cccaagcggc
     6421 gggcgggatc tcccagaatt tgcggccgag ccagcgcgcc gaaccggggg agtcgtagac
     6481 gttgttgacg agaatgtcga ggcggccctg ttcttctcgg acgcgctcga acagtttcac
     6541 gacccccgag ctgtacagat gatcgcagat caccgggacg ccgacgccgc cgagggcgtc
     6601 gacctcggcg gcggcgcccg cgacggtgcc gggcagctgt ttggccttga cggtgcgtcc
     6661 ggtgaggtac acggtcgcgc ccgccgcgcc cagttcgagg gcgatgccct tgccgatgcc
     6721 gcgactggct ccggtcacca ccgcgacgcg tccggcgagc accccgggtg tatcgctcat
     6781 gatctcagga ctctaccgtg aaatgggaac gcgttctaga tttaccccga gatgggtgcg
     6841 ggctcaccga gactctgcaa cccagcagcg ccgccgtcgc gttcaacacc ggcaccgccg
     6901 cgcggcggcg ccgcagcccg agccacgcgc tgcacgccag acccgtcagc agcagtacat
     6961 cgaacccgac ccaggccagc cgccactcat aggtcgtgta gccgttcggg agttggaccg
     7021 ccaaccacag cgtccaggga acaaggaata acgcgccacc tgcggtgaca gccaacagaa
     7081 ctcgtcggtt cacatcgacg aacctaccga agcgcggaat tattctcctg cgggcagcgc
     7141 tcggtcgcgc aggccgagga attggtcgag cagcgccaga ccctccacgg tgagacggga
     7201 agtgggcgcg gccaattcgt cctggaggat ctccaatccc ctggccgatt cgacaccggg
     7261 cgcgccggga gcgacctttc gccaaccgac cgccgtcttc cagtccggat cctcgcatgc
     7321 ccatgcccac agcacctcgc gcaccacgac gggcagcacc gtgtagacgc gcgagcactc
     7381 tgtcccggtt cgggtttcga gttggtagac gtattcgtgg cggtgggcgc gtatgcgatc
     7441 gcccgcgcgg gtgagggtga ggtcgggatc gttggggtcg gcggcggcgg tgatcagatc
     7501 ggcgagcagg gcgggggtga gatagggcag cgtgtgatcg ggcatggtga cctcgacctc
     7561 gacgcgctcg cgcgggttgt agaggcagcc ggtggcgata tcgaggacgg cgaggtcgcg
     7621 gtccttggtc agattcagcg ccgcgagcag gtggtgggcg cggtcgtgac cgcgcgcgtg
     7681 caggatcgcg ccccccgccc ccgcggtcag tccgtaggca ggatcgaggt cgatggacag
     7741 cgcgcgcagg gccgggtccg gtcgaccagg gtcggtgcgc aggcgcgagt agatctccaa
     7801 cgcctccagc gcgccgtcga tatcggctgg gagcagcgcg aattcgtgcg tggccgtgag
     7861 tccgtcgagc accgagcgca gttccggcgt cggccgcacc tccacgctgc cgtcggcacg
     7921 cgtcgcggtg gtcgcggcga gtcggatgac acggtcctgc caccagaaga ccgaggaggt
     7981 gatcgcggcg gagcaggcga tcgtgccgag cgcgtccagc acgacctcgg aatcgggtcc
     8041 gcagagcgga tgcgcataga gttcgcccgc gcctgccgcg acgaacaacg ccccgtgctg
     8101 cccgatcacc ggatagtgct cgagcctgcg aatgtgcgcg cccgcgaact ccgatccggt
     8161 gagcacggcc agatcggtct cgccgcgacc ctcccacccc agttccagac tctccgcgcc
     8221 ggaattggcc tcggccgacg cgagggcttc ctcgacgccg atctcccact ccgccaacaa
     8281 ctccggcgtc accgcgcgac cgagaggagc gagcgtcaaa acctcgacga gtcccggcgc
     8341 gaccattcgg tgcacggccg ggcccccggc ggcggccaaa cgcaatcgca gcaacccgcg
     8401 cggatcggtc tgttcggcga ccgaaccggc atgggtgcgg ggggcatccg atggcggtgt
     8461 catcaagtca tctccccagg ggtcgagtgt gacctcgacc ataggtggat cccgcgcgca
     8521 ttgccgtcgc tgggaacggg ccgcagtctg tcgaagccgt cgatcgcaag ccggatatgc
     8581 cacactgacc ccatggacga ggcggatgtg ccgaccgatg tgtccgatac cgcgcggtgg
     8641 gtggccgcct accgcgcgca ggagagcgcc cgcccggacg cgctgttccg agatcccttg
     8701 gcggacaagc tcgcaggcga acagggccgg gcgatggccg cggccgccga gcggaccctg
     8761 agtggcggct ggccgatcgt ggtgcgcacc aaactcatcg acgacctgat ccgcgactgc
     8821 ctcgcgcagg gctgcgatcg ggtgctgaat ctggccgcgg gcttcgacac ccgcccctac
     8881 cgactcgacc tgcccccgga attgctctgg gtcgaagctg atctgcccgc gatgacgcac
     8941 gagaaagagg cggcactggc aggcgcgaca ccgaagtgcg cgctgctgcg ccgcgcggtg
     9001 gacctggccg acgaacaggc gcggcaggca ttcctggacg aggcgctcga cgcgcacgaa
     9061 ccggcgaaca aaccggccac caaggcgctg gtgctcaccg aagggctgct gtcctatctc
     9121 gaacccgata ccgtggccgg gctggccacc gtgctggatc gtcccgagat cgcctggtgg
     9181 atcgccgata tcgcgctcgg gctggccaag atgaaattgt cgatgttccg caatgcgcca
     9241 ttgcgattcg atccgccgaa cggtgtcgca ttcttcgagg aattgggttg gcggatcacc
     9301 gatatggagc cgatcttcat caatgcgcgg aaactgcgca ggatgccgtg gtacatgcgg
     9361 ccattcacgt atctgccgca accgaatccg cgcaaacccg gtaggcaggt ctggtcggcg
     9421 gtcacccgcc tccagcacga atgaggtggg ctgcgaaact tgatcgcccc gaaacttgaa
     9481 ttccgcgttg atctttcgca ggacgggcgg actgtccgcc gatcgggcgg tcgtcacgca
     9541 ggtggtcggg cgtcgatctc gacgacgtcg cgaacaatcc accgcagccg ggaatgccat
     9601 tcgacgccgt tgtcctcgtg ccatatcggc gagagtctcg gggcgaaaat catccaatac
     9661 agaccaattt attcccactt tctcgagttg cagtcctgtt tgttactgta gccgacgtga
     9721 ggcacattgt tcgctgcggc gatcggaatg tgtgccgatc atcctgtcaa ttccgtgttt
     9781 cacgtcagcg acgaggagga cgaaatggac gagaaatcac ccgagaaatc agagtacgac
     9841 gatgttgtca tcgaggaact cgatgcgata tcggaggccc ataggtgtgg gtgtcgttgt
     9901 gggtgtcgtt gcggttgacg atgacctgac agctccccgc cggtcaccgc gatggccggc
     9961 ggggtcgaca tgttctttcc cggctgcgag ggaggttctg atgggttctg tcctgcggtt
    10021 cacacgtcat ctgggggtgc agaccgtagc gggggacgga gtgtatgtct tttcggaagg
    10081 ttcgcggcga acccggctgc acggcgggtt gatggagcgt cttgcgccgt ttctgctgac
    10141 aggcaggagt cgaggtgata tcagcgccgc gctggccaac gatttcgaca gcgacaggct
    10201 ggattcggcg ttggcgcggc tggtggacgc cggtttggtc gtggagtgcg atcccgaggt
    10261 ggacccacgc gccggaggct actgggagct gtgcggcctg gacggtgacg cggcggtggc
    10321 gcggttgcgg gaccgaactg tcgacgtggt gggcatcggt caggtcatcg atgcggagtt
    10381 cgccgccgca gcaatggctt tgggtcttca ggtggggcct ggcagtccgg atcttcgggt
    10441 ggttctcacc gacgactatc ttcgtccgga attggcagat cacaatcgtg cacgtttgac
    10501 cgatggcggt gcgtggatgc ctgccaaacc ggtcggcagc acggtgtgga tcggcccggt
    10561 gttcgagccc ggacgcacgg gctgctggcg ttgcctgtcg acgtatctcg aatccaacca
    10621 gttggtgcgg tcatatctgc ggcagcggac ggacgcggcg ggtccgccgg tcgccgccga
    10681 aatcggcctg cccgcaacgc ggcaactggc ggcacacatg gcggcgttgc atgccgcgca
    10741 gtggctgacc ggcgccgagg tcggggcgga tcggccgagc gcaccgcata cggtcatgtt
    10801 caccttcgat accatcggct ggcagtggag caggcatgtg gtgcgcgccc ggccgcaatg
    10861 tccggagtgc ggtgatcccg atctacagcg gcgcctgcag tgggatccgg tccaactggt
    10921 ctctcggcca aagatattca cgaccgacgg cgggcatcgc gcgaagacac ccgaggcgtt
    10981 gctggccgag tacgggtcgc tcatcagccc gatcaccggc ccggtgacag agttggtgcc
    11041 gagttcggcc gccgatgatc tgttcgccta tcgagcgggt gcgaatgcgg ccatgtcgat
    11101 gaccgatatt tccgccctgc atgcgggtct gcgtcaatcc gccggcggga aggggatgac
    11161 cgatacccag gccaaagcgt ccgcgctggc cgaggcgatc gaacgcttct ccggcgtgta
    11221 ctgcggtgac gaagccaccg tcaccgcgag gatggatgag ctcgacggtg ccgcgatcca
    11281 tcccaactcg ctgcaactct acagcgaccg gcagttcgcc gagcgggccg cctggaatgc
    11341 gaaaaagatt ccgtaccagc gggtgtgcga tccattcgat cccgatgacc gtatcgagtg
    11401 gaccccggtg tggtcgctga cccacaacgc gacccgatac ctgcccaccg cgaatctgtt
    11461 ctacgactac ccacagcagg cgggtcggtt cgcattcgcc gactccaatg gcaacgctgc
    11521 aggcggctgc ttggaagatg ctgtgctgca aggttttctg gagctcgtcg aacgcgacag
    11581 cgttgcgctg tggtggtaca acaggattca gcggcccgga atcgacctgt ccggcttcga
    11641 cgaaccgtat ttccagcgat ggcagcaccg ctaccgcagc ctcggccgcg aggcatgggc
    11701 cttggatctg acctcggacc tcggtatccc cgctgtagtc gcgctgtcgc gtcgcatcgg
    11761 tgcgccccgc gaggacattc tcatgggatt cggtgcgcac ttcgacgtca agatcgcgat
    11821 ctcacgggca ctcaccgagt cgaaccaatt tctgggatac gacagcaccc ccgtcgagga
    11881 tctcactccg gaattgcgcg agtggtacac cgaggccacc ctcgacaatc agccatacct
    11941 ggtgccggcc gacgagccgt cgcgaacctc tgccgactac cacgatccca gcaccgacga
    12001 cctcgccgag gacgtgcggc tggcccagcg gatcgtcgag aactccggac tggaaatgct
    12061 cgtactcgac cagacccgcc ccgatatcgg gttgccggtg gtcaaggtga tcgtccccgg
    12121 cctgcggcac ttctggaccc gctacgcgcc ggggaggctc tatgaggtcc cggtgcgcat
    12181 ggggtggctg cccgaaccga cccccgagag cgaactcaac cccatcggga tgttcctgtg
    12241 aacccgccca ccgccatcgc cgacatcacc atgatcgaca acgtcatgcg gttgcggacc
    12301 ggcgtcgaga tcgagcacga cgccgacctg ctgaccctca ccggcgcgca cggatccttc
    12361 acgctgcgca atatgtcgga cggcctcgtt tcggcgatgc ggcggctgca ccgcgccgtg
    12421 cccctctccg aattgaactc ctcgctcacc gatcatgaac gacaccaact tcaacgcatc
    12481 ctggcccgcc tgaacaagct gctcgcacgc tgcgttgtca tcgacgacac cgagttgatg
    12541 agcctggaac ccaccgcacc cgacgccacc tatcacccga gcccaccgcg ccccggcgca
    12601 cgactgcgac tgtcgaagtt cagtttcgcg cgttcccgag acgatctgct ggttctcgaa
    12661 tctccactcg cgcaccaccg cgccctacta ccgcatccgg cggcaggcgc tgtcgtcgcc
    12721 gcgctcggaa caaccagcgg cgcaatcgaa ctcgccgatg ccgcaggtct gccactgccc
    12781 gtcgtgcaca acctgctggc ccacctcatc ggagcgaacc tggtcgaggt cgacgacccg
    12841 gaatccggcc gattcgcctc cgaaaccgac aatgcgttgc gtcagtggga ttttcacgat
    12901 ttgctgttcc actcccgcag ccgctccggt cgcaccgacg acccccacgg cggcgtgttc
    12961 tcctacctcg gcgacatacc accgcatccg gcgatcaagc caccccccaa cggacccgcc
    13021 gtgcagctgc cccgaccgtc ctggcgcgac atcgccgacc gagacccaca actgagcacc
    13081 gtcatggaac agcgggtctc gatacgcgaa cacgccacgc tgccaatcga tctcgaccag
    13141 ctcggcgaat tcctctaccg agtggccagg gtccggaccc gctcctggcc cgacggtgcg
    13201 cactacgaga ccacgactcg gccctacccc ggcggcgggg ccgcttacga gctcgagttc
    13261 tacctcgcgg tgcaccgatg cgacgggttg cggcagggca tctactacta cgaccccctc
    13321 gagcatcggc tcatcctgat caatgacaac gaatccgact gccggacaat cctggacgac
    13381 gcatccgccg ccaccgcctt ccagggcaat ccggatatcg cgatcacgat tacgtcccga
    13441 ttcggccggc tctcctggaa ataccgcggc atcgcctacg cgctgaccct ccggcatgtc
    13501 ggcgtcctct accagagcat gtatctggtc gcaaccgcga tgggattggc gccctgcgct
    13561 atcggcagcg gaaactccga cgctgcgggc cgaatcctgc gactgaacta caccgaggaa
    13621 tccccggtcg gggaattcgt gttgggaagc cgtcctcacc cgcacgctcc ggacaccgac
    13681 tgataccggc gctccggcac acctcaccac gggctcggaa cagggtgtcg cgcacgcgta
    13741 gtgccgacaa ccggtggggc gtgttgttcg ggcatgccgg gcaatatctc ggcgaaagcg
    13801 ctggctcatc ggccgaggtc ggacaggatc tcccgcgcgg cacgggcgcc ggattcggcg
    13861 ccgccgttca tgtagccctg cgactccgac gaggtgtgct cgcccgcgaa gtgaatattg
    13921 ccctggcgtg cgccctcata gccgaagaag cggtggctgt agttggtcgg catggcgctg
    13981 taggcgccgt tggcgagtgg atccgcatgc cacgccgaca gtgtcgcccg gccgttccac
    14041 agcgtgccga tgccgggcac cacccgctcg aattgtgcca gtacggtgcc gacgcgggtg
    14101 cgaaccgcga ggtcggcggc ggtagggaag gccgacggag gtgcgaaacc ccgcgcgtcg
    14161 agcccgccac cgtactggat cgcgatgccc tgcttaccgg gttggcccgc agtggcgtcc
    14221 cagatcgcct gatagccgac atcggtgaag ctcgctccgt tcgacactcc cggccactgc
    14281 ccgcgcccca cccacggccg cgaggtgaac tgcatattca gcttggtgct ggtgctcatc
    14341 ggcaacgcat cgatcacgcc ggtcatgcgc gggtcgaaac ctgctgcgct gtagtcgata
    14401 tgcttcagca cgccgaccgg cacggccagg atggtgtggt cggcccgcac cgtgcggcgg
    14461 gtgcccgcat cgtcgaagat cagcgtctga ccgccatcgg aatcgcgaac gatggcctcc
    14521 agtcgccatt cgtaccgaat cgccccgtcc ggaagtgctt cggcgatcgc ccgcggcagc
    14581 cgctgactgc cgcccgagat cttgtactgc tcatcggaat tgccccatgc ccgcggatca
    14641 tcgagggact tctgggtttt catcatcgaa accagattca gtgcggtctg atcggcggtc
    14701 ggcattccgt actccaccac ataggcgtcg tcgaaaagcc gtgcgatcca attggaatag
    14761 ccaccgggaa cgcgagtggc gatccattcg gtcaaggaca tggtgctcag cgcgataccc
    14821 gcgggcgtgg cgctgttcca ggtcggtgtg gcggggcagg cggcggcatc gacctgcaac
    14881 gcccgaaaca ccggctcgaa gtcggcgatg aatttgtcgc gcggaacgta gccgccgtcg
    14941 aaatacagca ccggcgaact acccgcaggc gccgcggaca gggtatccac cagcggtatc
    15001 ccgaagcggg aacacaaatt tcgtatcgtg tggtgatcgc tgtcgacccc ctccccaccg
    15061 tactcgctga cctgaccgcc atcccaatac tcgcgctcgg agaacatgcg gccacccacc
    15121 cggccccgcg cctcgtacac cgtggccgcg atgcccgcat cggcgagcgt cagcgcggca
    15181 ttcagtccgg cgataccggc accgatgatc gcgatccgcg gtgtgtccgg gccgagggac
    15241 tgggcgacgg ccggttgccg tccagccaga ccggcgaata ccgctgcccc cacaccggcc
    15301 ttcagcaatg tgcggcggtc gaagatcggc gcacgaacct cgtctaccgg gatcccaagc
    15361 cgctcggcga ccatgtattc ggtgaccgtg cgctgcacca ttcgcagcat cggagtacgc
    15421 ggtgacatag cggagcgctc ctgtccggag gggccgtcga gcattccagc aaatctgtct
    15481 gcggctcaaa ggctaccaat gcgcgcggcg caggtaagaa ccatgcggtg cgcctcccgt
    15541 cgtcccgaag cattgagaat atgcccgtga aaggcatggc cgaggcccgc gcgaagggcc
    15601 acctcaaagg caaggttggt cgtgcgcgtc gatcaagatt tggatgtcga ttctcgtcat
    15661 tgcgtgcagc gcggtcagga cccggcctgc tgcctcgggt tcggagttgt ccagcagttt
    15721 gcgcagggtt gtcgggagga tctgccaggt cactccgaag cggtcggtca gcgaaccgcc
    15781 cggcccttct cggccgccgt cggtgagggc cgcccacaga gtatcgatct cgtcttgggt
    15841 gtcgcattcg acgtggggcg agatcgcggc gccggtgaag gagagttccg gcccaccgtt
    15901 gtaggcgatg tagcgctgtc cggccagctc gaaggtgacg gtcgagacac cgccgtcgag
    15961 ggcgcgttgg gtatcgagga tcttggcgtc ggcaaacgcc ccggtgtagt ggtcggcggc
    16021 ttcctcggcg cgcccgtcga accacaggaa cgtacttacc cgctgcatgt ctatctcctc
    16081 ggtatcggtt gtcagggttc ggttttcacc gtggtgtagt cgtcgagttc gacgatgttg
    16141 gcgagctttt ccatgccgtg gccgatcaag cggcgaggta ggaagggcat catccggaca
    16201 gacacgttgc gcagccacaa ctgtgcctgc gaatcgggca tcaggccgct gtcgcccgca
    16261 ccgcgcgcga agtgctgggc tcggccggcg aagtcgcgca tcttccgctg atacgcggga
    16321 aaggcgtggc gggggtcgcc ctcggccgcg gcgagttcgc cggccagaat gtaggcgccg
    16381 accatggcca ggctggtgcc gatgcccgac atcggtgagg cgcagtaggc ggcatcgccg
    16441 agcagcaccg tccggtgacg cgaccaggtg tccacgtgga cctggccgac ccggtcgaag
    16501 tagaaatcgg gcgagtcccg gattgtggac aggatccggg gggtttccca cgcgtctgtt
    16561 tcgaaggcgc gcaccacgat ccgtttctgc tcgtcgatat cgcgccggtc gtagcgcagg
    16621 acgggcgaac gcagaaagaa tccggccaac acagcgtcgg gtgtcggttg cggacccagg
    16681 ccgaccgttc tgccgggcct gccggctccg gcgggtgtgg tgtacatcag ttgccagccg
    16741 tcgagatcca cggtcgtggt ggtggtgaac agcgctatgt agcagccgag gtcacgcagg
    16801 tagcgttcgg gcggcccgaa caccagccga cgaaccgtgg agtgcacacc gtccgcgccg
    16861 accagaaggt cgaaccgccg ggtcccgccc gtctcgaact cgacgcggac accgtcgtcg
    16921 tcctgttcga ccgcggtgat cgaatcgccg aagacatact cgacatcgtc gcgggtggcc
    16981 ctgtacagga tccgcgccag atccgtgcgc cggatcgcca tctccgcgat cgggccgccc
    17041 gaatccccgt acaccgcggt actcaacgtc gccacccgct tgccgtggcg atccacgaac
    17101 gccatcccgc gcgcaccggt gtgtgccccg cggacctccg cgacgatgcc catccgctcg
    17161 gccacctggc gggcggtccc acggatatcg acagcctgac caccgctacg cggcgcgtgc
    17221 gcgcgctcga ccacggtgac gcggaacccg gacctgtgca accaatacgc caatgtcggc
    17281 ccggcgatcc cggcgccgga gacgaggatg ctccgatttc tcatggtttc cttcctcctg
    17341 tgtcgcagga gacgacggca cgcgatacga cgtggctgtc gaagtcgtac atgcacatgc
    17401 gtacgtcgta tccgatcatc gagaatgtag ctgtttcagc caggtagatg ccatgtgata
    17461 gcaaaagaag tcccctagtt cacccggaat tggactagta cactgatgga agatgcggag
    17521 tgctcggcgc acagatcgga ggccgcggat tgtcatcaac acagcggaca gacccgccct
    17581 accgggcgat tgccgaagag atccgccacc ggatcacgac cggcgaacta caaccagggg
    17641 accgggtgcc ctccgtacgg cgcatcactc agcggtgggg cgtcgcgatc gcgaccgcga
    17701 cacgggtgat agcgacgctt cgagacgagg gactggtcga aacgaaggtc gggtccggca
    17761 ccgtggtcag cacacccggt gaccgcgagg cgtcggaaat cccggccgcg ccaccggcgc
    17821 cgcgcgccgc ccggacaccc cacgacgcga tgaaccgtcg gcacatcctc cgcgctgcga
    17881 tcgcgatcgc cgacgtcgag ggactcgacg cggtgacgat gcggcgcctc gcggcacacc
    17941 tcggcgtcgg ccccatgtcg ctgtaccggc acgtggcgaa caaagacgaa cttctgaccc
    18001 agatggccga cgaggtcttc ggcgaagcga acctgcccga gccggggcca cacgggtggc
    18061 gcgccaagct cgaactgatc gcccgcctgc actggcagct atgccgcagg cacatgtggc
    18121 tacccggggc ggtctcgttc acccgccccc tgctcgtgcc caacatgatg gcccacaccg
    18181 aatggacact ccgcgcactc gacggactcg ggctgccgat agttacccga ttccgcgaag
    18241 cactcaccct gcacgccctg gtagccaccc tcgcgctgtc cctggccgag gaagccgaag
    18301 ccgaacgcaa caccggcgtc accctcgacc ggtggcgggc gatgcagcgc acacccaccg
    18361 ccgaactccg cagcggcgga cgattcccac tactcgcggc agtccccgaa gacaccgtgg
    18421 cagacctgga cggactcctc gaatacagcc ttgcccgcca cctcgacgga ttcgccgccc
    18481 tcgtgaccga acgccgaacc gatcatgacg ccgccaacaa ctgaccaggg gtatgtccga
    18541 ctattcttcg gtgggaattc gggtacgccg gtatcggccc gagccggcag gatgaccgtg
    18601 caggccgagt ggaaccgttg ctcggcggac acgcgccctg gagattgccc atgcgaattc
    18661 gtcggtcggt acacgcagga ttggttgccg tcgccgcggc cgcgggaaca atgctcgcga
    18721 cgccgttcgc gcacgccgcg ccgggggaca gggtgaactg cgttccggtg ccgatcgctt
    18781 cgcgcctcga agtcacctgc accaataccg ctgccgaagc cgccaccgca accatgaccg
    18841 ccctgtgcag caatttgcgg atactgcacg aacccgagtt tccgatcgcc ccggccgaca
    18901 ccgtgacatt cagtcaggac tgcggggcgg gtgcaacctt gctctcgtgg aatgccagcg
    18961 gcgagaccat ctccgagcgc gcacaacgcc tcgcacgtga gcgcagcgat gagcaagaca
    19021 aacagcgcaa gcagcgcgag cagagcgccg aagacgacaa gcatcgcgag caggagcgca
    19081 agaggcgctc ggaattctag agcgggattg ggccgccgcg ggcagcctgg aaaatctcgg
    19141 ctacgaccgg atagcgggcg agaacttcca ggcgccgaac gcgttaggtg agccggtccg
    19201 gttcggcggc ctcgggtgct tcgatgatcg tgatcggtac cccttggccg gcaccgagcc
    19261 tgtgggcgtt ggctttggcc caggcgctga tcgcgatctg ttccgggctc gcgcgtggtg
    19321 tccagcggcc atgccgcacg ctttcagcgt tcatccggtg cgcggtgaga agccgcgaga
    19381 ggtgttcgaa ctcggtcggt gtcacgaagg ccaggtagta gtccggcccc gattccagcg
    19441 acgccaggac agtgccgagg gcgaaggcgc gctcaccgat ctcttcgagg aatgcttgaa
    19501 ggtaaccgat gtgatggtcg ggggcatgtt cggtgtcgaa ggcagcgacc caatcccagg
    19561 gcagtgcggc gggataggag ctcagcgatg tcaactgctc gcggacggac cccggatcgg
    19621 cctcgcggga gatgaccgcc atatcggcgc tcgggcttgg agattcggcg tcgcgaaacg
    19681 attcgtcgcc ctcgggggtg aggtgtgccc gtcgttgggc catgatggcc cgcacgcgga
    19741 attcggcatc gggttgcctg cggacccagt catgggagta ggccgcgtcc tgcgaggtct
    19801 ggcgcactat gcggtccggt tcgggcgggg cgggccagaa ctgtaggagg tatcggtcca
    19861 gtactggctc atcgtcgagt ctgacgtcct tctctcgtgc ccggtccatg ccctgcgcgc
    19921 agtaccgcac ccgatagtcg agaccttctt tcaagtccag ttcccaggag tcctcgcctg
    19981 cccactgcac caggaagctc tgatccgaga gcgggtagaa ggagacctcc accacgtcct
    20041 cccatgccgg atccagcggg ggagcctggc cgcgcacttc gacggtgaag ccgacgtcgc
    20101 cggtgtgcaa cccggtgtgc aggaaaagtg cgccgggcac cgcggcgccg cacagtcctg
    20161 agttctgtcc ggcgaacgcc tcatgcatgg gcggggtgcc cccaggggca ctctcgacat
    20221 agatctggct gcaggagaca cctacctcgc catcgagtct gaacacttct cacaccatcc
    20281 ccaccggcga gagcccatca tcgccgggcc gcgaggcccc gaatagcaaa gggacgttca
    20341 gctcagcagc gtcggtgccg accaactcga aagcgaaagg gccgtcagga gtgtggtgcg
    20401 gtctgattcg ggaacgggcc atgcacggca gcgtagacaa gcccaccgac acggaggctc
    20461 cgctcttgtg cccgagcaac ccaccgagaa gttcgacgcg catgaactgc gatccatgcg
    20521 aacatatgtt cgtgtccagg gatagcgaac ggattgccac acgggccgag gcgtcgatcc
    20581 tgcatgcgga tctcgattcg ttctacgctt cggtggagca gcgggacgat cctcgattgc
    20641 gggggcggcc ggtgatcgtg ggcggcgggg tggtgctggc ggcgagctat gaggccaagg
    20701 cgttcggggt gcggacaccg atgaacggtc ggctggcgcg gcggctgtgt ccgcaggcga
    20761 tcgtggtgcc gccgcgcatg gcggcgtacg cggaggcgag ccggaaggtg ttcgaggtct
    20821 ttcgcgacac cacgccggtg gtcgagggca tctcgatcga tgaggcattc ctggatgtgc
    20881 gggggctgcg gcggatcgcg ggggaacccg agatgattgc gcgacggttg cgtgaacagg
    20941 tcagaaccga agtggggctg ccgatctcgg tcggtatcgc gcgcaccaaa tttctggcga
    21001 aggtggccag cgccgtcgcc aaacccgatg gattgcggct ggttccggcg ggtggcgaac
    21061 tcgagttcct gcatccgctg ccggtcgaaa gactttgggg tgtaggcgaa gtcaccgcca
    21121 ggacgctgca cgagcacggc atcaccaagg tcgggcagtt ggccgagctc ggggagtcgc
    21181 cgctgcgggc gctgctcggt cccggcgcgg cccgccacct gtacgccctg gcatgggctc
    21241 gtgacccgcg ccgggtcgag acgggtcgcc gtcgccgctc gatcggcgcg cagcgcgccc
    21301 tcggtgtccg gcaccgcgaa cccgacgaga tcgaggcgta tctgcacgga ctcatcgacc
    21361 gcctcgggcg ccgcctgcgc gccgccgacc gcctgagccg cacggtggtg ttacggctgc
    21421 gcttcgccga tttcgcccgc gccacccgtt cgcacaccct ggcagaggct accgaccaca
    21481 cacctaccct gttgggcgcc gcccgccgac tactcgccga cgccatgccc ctgatcgacg
    21541 accgcgggct gaccctgatc ggcctgtcgc tgaccaacct cgccgacgcc gacccgttcc
    21601 aactgagtct gccgttcgag gagcgcgccg agaacaccct cgacaccacc ctggaccgac
    21661 tgcgtgaacg cttcggctcc gccgccgtca cccgcgccgc gctactcggt cgcggcgagg
    21721 gcctctcggt cccactgctg ccggattgag ttcggcccgt taagctgccc cggagccggt
    21781 tcggcctggg gagctttttt gaaccgcgac gagccggacg agtccgcgac cgttggaggt
    21841 atcgccgtgc cctacgccgt actgggcctg atcacgctgg ccctgtgggt gtactgcctg
    21901 atcgacatca tcacctgccc cgacgcgggc atccgccatc tgccgaagat gggttggttg
    21961 atcgtcgtca tcctgattcc caccgtcggc gcgctgctgt ggttgttcgt gggcaggccg
    22021 gtgcgcgaga tcgcgccccg ctcgaacacc cggttcaccg aatacgatcg accgggccgc
    22081 cacatcgccc aaaatcccga cgacgacgcg gaattcctgc gcggcctgcg cgaacgcgcc
    22141 gaacagcagc gccgcgaggc gcgtcgccag caggagcagc gcggcgagga gcagtagccc
    22201 gtcagctcaa tgtccgccgg aatccagggg cgagagtggt cgcagggtca gtaggccatc
    22261 ggtgaggggt agcagcgtcg cgtcgatcac cactgcaacg tagccgcgtc gtattctcgg
    22321 cctatgaccg agcagcgcac caccttgcgt gcgggagatg ccgaactgac cgtcgatccg
    22381 gccaacggtg gccgtctgac cagtctgcgt gtgcgcgacc acgaactgct gcgccagggc
    22441 gaacgcttcg gctgtttccc catggttcct tggtgcgggc gaatcgcgct gggccgcttc
    22501 gagttcgacg gccgcgccta ccagatgccg atcaacagtc cgccgcacgc cattcacggc
    22561 accggtcgca atacggcgtg gacgactctg gaaaccaccg accggacggc ggcattcggc
    22621 tacgacctca ccgatccgtg gccgttccgg ggccgggtca cccagtcggt cgcgctggcc
    22681 cccgactcgc tcacgttgac catgcgggtc gactcggccg cggaatcctt tccggcgcag
    22741 gccggttggc atccgtggtt caatcgtgaa ctggcgggcg gtgatccggt ccgcatcgat
    22801 ttcacgcccg gctggcagga ggaacgcggc ccggaccatc tgcccaccgg tgctcgcgtc
    22861 gcacccggcc ccggcccgtg ggacgactgt ttcggcatgc ccggcggtgt cgaagtcgtt
    22921 ctcacctggc cgggcactct ggcactgcgc atctcttccc ctaccgaatg ggtagtcgtc
    22981 tatgacgagc aggaggccgc ggtgtgcgtg gaacctgaat ccggcccgcc gaatggtctg
    23041 aacactttgc cgcgcatggt cgcaccgagc gatcccttgg agatcaccac cacgtggagt
    23101 tggcgctgat ccagcggggc cgcttctcca gaacggtatg cccctcagat gacgcgtgaa
    23161 ccgcaggaca gaaccccacc gagaccttcc ctcacagccg gggaaaacaa cgtacgaacc
    23221 cgccggtcac cgtagtgacc ggcggggaaa tgcgaggtca gccgccgcaa cggcagttct
    23281 cggtctgcga cagggcgttc tttcgatcca ttgtcggatc tctgccgccg ccgattcggg
    23341 agccggcctc gcgcattttc ggagcctccg cgttccctct caccatcagt agtgagtgcg
    23401 tcgagaccga gatagaaagc gccggaaaat ttctcacctt cgaactgggt accgggggat
    23461 agcacaccat cgtcgatgac tcggcgcatc cgatcaacca ccccggccga aatatactgc
    23521 acaccacagt gatcactcgc ggtgtacgtc tatcgccggg tgagaaaccg ccggagttct
    23581 gcggcgacca gttcgggctt ctcgtcgttg aaggtcgcgg tgtgcccggc gtcgggaaaa
    23641 gtgacgcggg tggcggcggg gagtgtcgcc tgtagttggt cga
//
