LOCUS       NZ_QOCT01000006        22598 bp    DNA     linear   CON 18-SEP-2024
DEFINITION  Lactobacillus bombicola strain L5-31
            L5-31_S84_L001_R1_001_84__paired__contig_6, whole genome shotgun
            sequence.
ACCESSION   NZ_QOCT01000006
VERSION     NZ_QOCT01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lactobacillus bombicola
  ORGANISM  Lactobacillus bombicola
            Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
            Lactobacillus.
REFERENCE   1  (bases 1 to 251708)
  AUTHORS   Motta,E.V.S. and Moran,N.A.
  TITLE     Genome sequences of six Lactobacillus spp. isolated from bumble bee
            guts
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 251708)
  AUTHORS   Motta,E.V.S. and Moran,N.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUL-2018) Integrative Biology, University of Texas at
            Austin, 2506 Speedway, Austin, TX 78712, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 5.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 124.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003515825.1-RS_2024_09_18
            Annotation Date                   :: 09/18/2024 04:05:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,612
            CDSs (total)                      :: 1,555
            Genes (coding)                    :: 1,521
            CDSs (with protein)               :: 1,521
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 34
            CDSs (without protein)            :: 34
            Pseudo Genes (ambiguous residues) :: 0 of 34
            Pseudo Genes (frameshifted)       :: 12 of 34
            Pseudo Genes (incomplete)         :: 20 of 34
            Pseudo Genes (internal stop)      :: 12 of 34
            Pseudo Genes (multiple problems)  :: 8 of 34
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:28:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 180978
            Orig. end                         :: 203576
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QOCT01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22598
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22598
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22598
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12598](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12598)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(47..61)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: weak, score: 16.15"
                     /tool="antismash"
     gene            complement(181..2247)
                     /gene="glyS"
                     /locus_tag="DS833_RS04590"
                     /old_locus_tag="DS833_04590"
     CDS             complement(181..2247)
                     /EC_number="6.1.1.14"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glyS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014563469.1"
                     /locus_tag="DS833_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04590"
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="WP_118896575.1"
                     /transl_table=11
                     /translation="MTKDYLFEIGTEEMPAHVVTRSVNQLADKTTKFLNENGLKFKNIK
                     TFSTPRRLTILVEELAEKQDDIDEIKKGPAKKIALDQDNNWTKAAQGFARGQGMSVDDI
                     YFEELKGVEYAYVHVKKTGKKASEILLNMNKVVKAMTFPTKMRWAANDFEFIRPIHWIV
                     SLFGNEVIPVKLLDITAGRKTEGHRFLGDSVVLANTGDYEDALKDQFVIVDATKRKEMI
                     VTQMSELVKENNWKIKPDSSLLEEVTNLVEYPTVFAGTFDEKYLQMPAEVLITSMKDNQ
                     RYFEVYDQDEHLVNHFISVRNGNQDFLENVISGNEKVLVARLDDAQFFYDEDRKYPLSH
                     FVQKLDNVSFHDKIGSMSEKIKRVRIIGNFLAEKWQLDEQTIADFNRASELYKFDLVTQ
                     MVGEFAELQGVMGMHYASLAGERQTVAVAIKEHYMPTTAEGELPQTIVGSLLSIADKLD
                     TIITFFAAGMIPNSSNDPYALRRYAYGIVRILLNQSWSLPFNKVLPEIVTELDGQTSAK
                     LPKTELQDDEIASFIRDRINQYLQRNQFKYDIIDAVLASNQQDPIQILSAANVLQLHHD
                     DEQFKPVVESLIRINNILKKAEFKGQNIINPDLFENESENKLFIEVNNLSKLTNLTALY
                     EGFVGIQPIINLYFETNMIMAKDETVKNNRLAQLKLISELATGLGDLSKLVIK"
     gene            complement(2240..3157)
                     /gene="glyQ"
                     /locus_tag="DS833_RS04595"
                     /old_locus_tag="DS833_04595"
     CDS             complement(2240..3157)
                     /EC_number="6.1.1.14"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004820 - glycine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006426 - glycyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glyQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006584805.1"
                     /locus_tag="DS833_RS04595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04595"
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="WP_118896514.1"
                     /transl_table=11
                     /translation="MTKKKLNIQNMIFKLEEFWSSKGCMVMPSYDVEKGAGTMSPYTFL
                     RAVGPEPWAACYIEPSRRPADGRYGDNPNRLFQHHQFQVVIKPAPTDIQQYYLDSLKVL
                     GINPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEVSQFTYFQVVGELEVKPTMSEIT
                     YGVERLASYIQDVNSVFDLEWGNGVLYRDIFKEAEYENSKYAFEESNQEDLLKFFDVYE
                     KTAQELIKLNLVQPAYDYILKCSHTFNLLDARGAVSVTERAGYLARIRNLAHEVAVCFV
                     EEREKRGFPLLKSAEDKKAGLEND"
     gene            complement(3403..4158)
                     /gene="recO"
                     /locus_tag="DS833_RS04600"
                     /old_locus_tag="DS833_04600"
     CDS             complement(3403..4158)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005719723.1"
                     /locus_tag="DS833_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04600"
                     /product="DNA repair protein RecO"
                     /protein_id="WP_118896515.1"
                     /transl_table=11
                     /translation="MARELKEVQGIIFKRQKYNEADVLAKIITKNYGIITMLARGALRP
                     KSKLGAALLNFSYGTYIIYTNGHGLSNLRTYKNIKQFNHIFTDINKNAYSSFILDLIDH
                     AFIEYQHIDQYYLLADFALQKINAGVDAEMITQIVQMQLLAAFGVKPELRHCVICRKEK
                     GNFDYSIKYGGVLCSDHFYTDSNRLHLKPKETAVLRTIGLLPAERLGEITISAQTKKAT
                     RKAIDQIYQATIDLNLKTKKFLDELNLLT"
     gene            complement(4161..5069)
                     /gene="era"
                     /locus_tag="DS833_RS04605"
                     /old_locus_tag="DS833_04605"
     CDS             complement(4161..5069)
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="era"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013853975.1"
                     /locus_tag="DS833_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04605"
                     /product="GTPase Era"
                     /protein_id="WP_118896516.1"
                     /transl_table=11
                     /translation="MSNNEKNKSGFVALIGRPNVGKSTLMNYLVGQKVAITSNKPQTTR
                     NKISGIYTTSSMQVIFVDTPGIFKPHGELDDYMDKASLSSLNDVDLILFMVEPEKMGKG
                     DEYIVNLLQQVKVPAFLLINKVDQVNPNDLLGIIDEYRQLNLFKEFLPISATQGIGISD
                     LNQVLYDYLPEGPAYYDSEQITDRPEYFMVSELIREQLLNLTAEEVPHAAAVWVEQMNQ
                     YENNKLQIEATIYVEKSGQKGIIIGKGGKMLKQIGINSRKQIEDLLGEKVNLHLWVKVQ
                     RNWRSDPRFLKQIGYNKKDLS"
     gene            complement(5069..5593)
                     /gene="ybeY"
                     /locus_tag="DS833_RS04610"
                     /old_locus_tag="DS833_04610"
     CDS             complement(5069..5593)
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybeY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003618709.1"
                     /locus_tag="DS833_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04610"
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="WP_118896517.1"
                     /transl_table=11
                     /translation="MTPIDITYNDEVDFLQDKKCNWQKWITDLLLLAKNEIGKENNLEM
                     SINFVNEERSQRINYKYRDKNRPTDVISFAIEDGEDKFEIAAFAADPDFCEDIGDLFMC
                     PSVIRRHSEEYGTGWQREFGYTLVHGFLHLNGYDHIEPDEAKEMFAIQGKILKNYGLPL
                     YADQLDEGRGK"
     gene            complement(5593..6546)
                     /locus_tag="DS833_RS04615"
                     /old_locus_tag="DS833_04615"
     CDS             complement(5593..6546)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011254379.1"
                     /locus_tag="DS833_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04615"
                     /product="PhoH family protein"
                     /protein_id="WP_118896518.1"
                     /transl_table=11
                     /translation="MAQTNFIPRNPENIQKLVGVNDSNLDLLAEGYDISITDTGNQILL
                     AGDSNNCQKAIAVLKALDNVVSANINISAPDIVSAMKMADKGITEYFPDLYKKILIRDA
                     KGKPIRVKNIGQKNYVEAIEKNDVVFGIGPAGTGKTFIAVVCAIAAFKKGEVSRIVLTR
                     PAIEAGESLGFLPGDLKEKVDPYLRPIYDSLYSILGTNTTDHLMERGVIEVAPLAYMRG
                     RTLDDAFIILDEAQNTTDAQMKMFLTRLGFNSKMIVNGDMTQVDLPGRQRSGLVDAEYI
                     LKGISHIKFIQFSANDVVRHPVVAKIINAYEKKEQS"
     gene            complement(6568..7011)
                     /locus_tag="DS833_RS04620"
                     /old_locus_tag="DS833_04620"
     CDS             complement(6568..7011)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003628914.1"
                     /locus_tag="DS833_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04620"
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="WP_118896519.1"
                     /transl_table=11
                     /translation="MSLSEQIMADMKDAMKAHDKVKLNTVRMIKAALMNEKIKLGRELN
                     SDEELTVLNREKKQREESLADFVKAKRTDLVEETKKELTVIEAYMPKQLSQSELEKIVS
                     AAIAEVNGATKADFGKIMKILMPRIKGRADGKVASNLVKNKLS"
     gene            complement(7143..7319)
                     /gene="rpsU"
                     /locus_tag="DS833_RS04625"
                     /old_locus_tag="DS833_04625"
     CDS             complement(7143..7319)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003565673.1"
                     /locus_tag="DS833_RS04625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04625"
                     /product="30S ribosomal protein S21"
                     /protein_id="WP_046306945.1"
                     /transl_table=11
                     /translation="MAKTVVHENESIDDALRRFKRSVSRSGTLQEYRKREFYEKPSVRR
                     KLKSEAARKRKHY"
     gene            7505..8332
                     /locus_tag="DS833_RS04630"
                     /old_locus_tag="DS833_04630"
     CDS             7505..8332
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016776 - phosphotransferase activity,
                     phosphate group as acceptor [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003613012.1"
                     /locus_tag="DS833_RS04630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04630"
                     /product="pyruvate, water dikinase regulatory protein"
                     /protein_id="WP_090092009.1"
                     /transl_table=11
                     /translation="MTDETPKKEVNIIIISDSAGDTAFNNAVAAAAQFPDAQINYRRYP
                     FVYNKEKLAETFQEIEKYPNLVIIYSLVKDEMQLPVIRFIREHNIHGIDILSPVVEAIQ
                     SATGSRPLKKIGAQHKMNQKYFDRISAMEFAVMYDDGKDPKGFLEADVVLLGVSRTSKT
                     PLSLFLANKNLKVANLPLVPDTHIPKEIYQVNPKKIIGLTNDLSVLNEIRRQRMIAYGL
                     NPDTTYSNTDAIKKELDSAQTLYNELGCFVINVANRSIEETAALILDHLGIEE"
     gene            8401..8949
                     /gene="msrA"
                     /locus_tag="DS833_RS04635"
                     /old_locus_tag="DS833_04635"
     CDS             8401..8949
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003626428.1"
                     /locus_tag="DS833_RS04635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04635"
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_118896520.1"
                     /transl_table=11
                     /translation="MANTNKDKKQNFQKAIFAGGCFWCMVEPFDTLPGVKKVISGYTGG
                     HVPNPTYEQVASGLTGHTEAVEITYDPELMSYDQLLEYYWQVTDPTDAMGQFQDRGDNY
                     RPVIYYNSIQQQLAAEKSKQKLQESGRFTAPIVTKIEPAQPFYPAEEYHQDFYKKAPNR
                     YALEEAGGRLTFIKEHWQK"
     gene            9046..9924
                     /locus_tag="DS833_RS04640"
                     /old_locus_tag="DS833_04640"
     CDS             9046..9924
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003627473.1"
                     /locus_tag="DS833_RS04640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04640"
                     /product="YitT family protein"
                     /protein_id="WP_118896521.1"
                     /transl_table=11
                     /translation="MDRLDTFNRRYNLLSKISASFFYSIAVAIALNLFWGPGHMYSSGI
                     TGFAQLINTLSERYLPFTLTTSVMYFALNVPLLLVAWFKIGHKFTFFTIITVILGSIMM
                     RVLQPVNMHVDPLVCAIFGGMINGLGTGFALKNGISTGGLDIVGIVVQEKTGTSYGKVS
                     IFINLVIIAAAGVAFGWNRALYSALTIFINGRVIDAVYTQHQKLQVTIVTDQPQAIIDG
                     IQEKMHRGITIFHDVEGAYSHIEKKVLITVINRYDMYDVLQIVQKNDPYAFMSVTEVER
                     VYGTFKEQEIV"
     gene            complement(10001..12598)
                     /gene="lanKC"
                     /locus_tag="DS833_RS04645"
                     /old_locus_tag="DS833_04645"
     CDS             complement(10001..12598)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="DS833_RS04645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04645"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_118896522.1"
                     /sec_met_domain="micKC (E-value: 2.3e-126, bitscore: 416.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1e-17, bitscore: 58.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.4e-22, bitscore:
                     73.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLTGNEYMEFVKNDRSLFYYPNDEPKNKFKFIKPKTSFQESTDS
                     YWHYILFDHKLPQQGWKIHLTANIKDAQKLLLTVSQYLNNQQVSYKFIDTVDAMLLSNS
                     KYGDRTESGKFITVYPVNTAEFVQLLPALAKITQDFLEGPYILSDQEWQDSHVFYRYGA
                     FKAMKTVIDGAEVYAIIDNKHNLVEDKRLPYYYQPDFIVEPEQLKNNVQHYDQNEFKKL
                     MNYNVDFSLHYSNAGGVYHAVFKGKEWVLKEGRAFAGLDANGNDGFNRIKHEYKILKQL
                     AEIPTVVDVYESFKAWKHQYLVEEYLQGDTLADFVDSQYPFTANKQKKNEYLTKTVKII
                     TALLKAINQIHQKGIAIGDLQPDNIIILDTDKVKLIDFENAQKASAAYNPGLATPGYSD
                     FNAKTFAEADRIALYKIARYLILPTATGFDWAPELEAVQDKNISNEFGKQIVEFLHNLK
                     KQLNLNFNSDSRHPQYYYQNLTVPSTPFSLNQLNQNIAEVAKGISDNLNYNFKGLIYGD
                     IPQYSSEISYYSVANGAFGAIMALNRSQTLDQKSKQEINIWLEQQLPNLKKLLAEPTTD
                     IGLFTGLSGIATVLYEQGYTKISYSIMKKIQTNVALKLTNDISIYSGLAGVGLAFLCFY
                     GQTKKTIYLQNAIDLGKQVMQIIKHERYTEKTDSGLITGWLGVALFLWKLSIVTKAKQY
                     KQAALRIYQVVIKNSLQLTSDGAFIKDNSYSYERLIPYVNHGSAGLALLMIEFLQDDPK
                     VFTKKELEILLKILKQNDVFVTFFAGLFDGFLSLLILDNAFAICTNNKVTLKKKYNLLN
                     NYLVAQNGCVMVPGRFGFKCSLDLTTGSSGLLLLLTDIKQHTWNAWLPLLRSK"
     gene            complement(12620..14344)
                     /locus_tag="DS833_RS04650"
                     /old_locus_tag="DS833_04650"
     CDS             complement(12620..14344)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004898399.1"
                     /locus_tag="DS833_RS04650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04650"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_118896523.1"
                     /transl_table=11
                     /translation="MNKKIKLYAISWQFILGLILGIFGTFIEVLIPLIVRQFIDGKTHI
                     SAHINFRLAAVIVVTIIFSAIISAFCQYLISVAGNLKIAEVRMEIEQKLLTLPMSFFTN
                     QKSGQLSSHLINDAEVVQSFMTSSIPATINSLIAVLGSFIVLFHLDWQLTVFIVLSFSL
                     IILIAYPIGKISEKLSLTTQNKLSELSGQSTENIYNIRSIKLNNAYRPVLLNFKQVVVE
                     LFKVSNKTDRIFSIVGPIQTVFTLGIILLIIIYGGIRVQQASLSIGTLVSFLIYLFQVI
                     EPINMLGNFYTSYKQAKGATLELNKILNTPGEKSVYQVNSQILFAKNSCLTLKNASFSY
                     QKEPVLQNISLSFNSGQKIAIVGPSGAGKTTIINLLTRLYELNEGQLLLNSVSATNYDL
                     NTWRNLFAVVTQENTIISGSIYLNLTFGLTAIPEESDIWAALDKANLLEDVQKMPNGLQ
                     TLVGEQGIGLSGGQRQRLQIARAYLRQANFLILDEATSNLDPNSEKIITNTLNELIATH
                     QTTLIVIAHRLSTIVDSDKIYFLDNHQITGSGTHQELMQLVPKYKQFVNEEILAVEK"
     gene            complement(14418..14546)
                     /locus_tag="DS833_RS08205"
     CDS             complement(14418..14546)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DS833_RS08205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_255409268.1"
                     /transl_table=11
                     /translation="MDSLMRHIFGLQKKKVKHQKHSKYNNKKRKSLICGHTFFGIF"
     gene            complement(14712..16301)
                     /locus_tag="DS833_RS04655"
                     /old_locus_tag="DS833_04655"
     CDS             complement(14712..16301)
                     /EC_number="2.1.1.72"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity [Evidence
                     IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568728.1"
                     /locus_tag="DS833_RS04655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04655"
                     /product="type I restriction-modification system subunit M"
                     /protein_id="WP_118896524.1"
                     /transl_table=11
                     /translation="MTKLQTISSQLWTLTNELETNTDTTESKNYILAFICYRYLSEQQE
                     QYLVSSSAINVKKGQAINEAYLEQAGGAELNAYLKDIFSNLGYAIAPLDTWQSLVNKID
                     KGQVNLSDYQTIFANFDKNAALSKAAGQTFKGIFSNLNLADSYLGSSANERVKSLAKIV
                     KLVDSIDYQDEAGKDILGDISTGLISKYAAGKKEATFCTPPAVAKLIAKIVTADLPKAT
                     QSFTVYDPSCGVGSILSAIANDNNSAIAKLYGQEANLTAYNLARINLMLHHVLFTNMTL
                     FNTDALENDWPAEPNTKEIAHPRTFDAVVANPPDPQSWDNNQNKLTDPRFRNYGKLAPR
                     TKASFAFVLQGLYHLNEKGIMAIVLPNEVLFRSAAEAIIRKNLVEHPDGNQIDAVMGLP
                     PNLFYEGIRPMIILVLKKTRTSKDILFIDASKEFAKGKMKNYLTQENIDKIFKTYQKRV
                     AVPQYAYLASIEEIRANDYNLNVSQYITTSENKKIDLTEIDRLLVQDKKDIATLEAKIA
                     KDLKVLEIKRDQ"
     misc_feature    16483..16496
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.48"
                     /tool="antismash"
     gene            complement(16494..16925)
                     /gene="msrB"
                     /locus_tag="DS833_RS04660"
                     /old_locus_tag="DS833_04660"
     CDS             complement(16494..16925)
                     /EC_number="1.8.4.12"
                     /GO_function="GO:0033743 - peptide-methionine (R)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005728153.1"
                     /locus_tag="DS833_RS04660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04660"
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="WP_090092018.1"
                     /transl_table=11
                     /translation="MDQEQKKQQLKHLSKEQFEVTQHGATDYPFKGKYDDFYQKGIYVD
                     IVSKEPLFSSEDKYDAGCGWPSFTKPIQKLVYHRDQSHNMERTEVKSPEADSHLGHVFT
                     DGPVDQGGLRYCINSSALKFIPFDQLEKEGYGEYRKLFK"
     gene            17075..18262
                     /locus_tag="DS833_RS04665"
                     /old_locus_tag="DS833_04665"
     CDS             17075..18262
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     1.6e-65. Score: 213.5. Matches aSDomain:
                     nrpspksdomains_DS833_RS04665_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014565029.1"
                     /locus_tag="DS833_RS04665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04665"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_118896525.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.9e-65, bitscore:
                     213.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTLANNLSDTINRRIEKLPKSEIRSFSQKISQIPGIVKLTVGEP
                     DLNTPDHIKQAAIDDINRDDSHYAPEAGKEEYLNAVSDYLKKSLGVYYNPKNEICATVG
                     VSAALNVSFMAILNPGDKVIVPTPVWGVYFGIIKMAGGVPIEVDTSADNFILTAAHLAE
                     VMENEGNGAKAVILTDPSNPTGRVYAKKDLKELAKVIVDYNLFALSDEIYAELIYAQKK
                     HYSLTQIIPDRTILLSGLSKNFAMTGWRIGYIAAPKEIMQTISKINSFMITSVTDNVQI
                     GAAEAISHGEQDYIEARAIYERRLHIIQTGLEKNGFTMATPEGAFYIFAKIPSKFGTDD
                     VAFATDLANKVKVGVIPGSYFGAGGQGFVRLSYASSEKCLRTAVERITTYVNEQL"
     aSDomain        17183..18235
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DS833_RS04665_Aminotran_1_2.1"
                     /evalue="1.60E-65"
                     /label="DS833_RS04665_Aminotran_1_2.1"
                     /locus_tag="DS833_RS04665"
                     /protein_end="387"
                     /protein_start="36"
                     /score="213.5"
                     /tool="antismash"
                     /translation="IVKLTVGEPDLNTPDHIKQAAIDDINRDDSHYAPEAGKEEYLNAV
                     SDYLKKSLGVYYNPKNEICATVGVSAALNVSFMAILNPGDKVIVPTPVWGVYFGIIKMA
                     GGVPIEVDTSADNFILTAAHLAEVMENEGNGAKAVILTDPSNPTGRVYAKKDLKELAKV
                     IVDYNLFALSDEIYAELIYAQKKHYSLTQIIPDRTILLSGLSKNFAMTGWRIGYIAAPK
                     EIMQTISKINSFMITSVTDNVQIGAAEAISHGEQDYIEARAIYERRLHIIQTGLEKNGF
                     TMATPEGAFYIFAKIPSKFGTDDVAFATDLANKVKVGVIPGSYFGAGGQGFVRLSYASS
                     EKCLRTAVERI"
     gene            18348..18842
                     /gene="tpx"
                     /locus_tag="DS833_RS04670"
                     /old_locus_tag="DS833_04670"
     CDS             18348..18842
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0008379 - thioredoxin peroxidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016684 - oxidoreductase activity, acting
                     on peroxide as acceptor [Evidence IEA]"
                     /codon_start=1
                     /gene="tpx"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004047950.1"
                     /locus_tag="DS833_RS04670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04670"
                     /product="thiol peroxidase"
                     /protein_id="WP_118896526.1"
                     /transl_table=11
                     /translation="MQITRLSTPLSTNGQPPKVGEILPDLKVEKADGSIVNLSELINKP
                     TLISVVPDINTSVCSISTKRFNSEVDKYDNINFYTISTNSPSDQRNWCAAEGVVKMELL
                     SDEKFDFGKKMGLFIEKMGLDSRSIWIVDTNQKILYQELIVEMTNEPNYDAALAFLDTL
                     N"
     gene            complement(18898..19398)
                     /locus_tag="DS833_RS04675"
                     /old_locus_tag="DS833_04675"
     CDS             complement(18898..19398)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003639107.1"
                     /locus_tag="DS833_RS04675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04675"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_118896527.1"
                     /transl_table=11
                     /translation="MLRKYHYAFGCYGIIGNQSELVVIKKHGGPYTNRYDLPGGSLEDG
                     EGLDQAILREIREETGLLVQVYQQLGITSFKYPWDYENWHFNQHFCVFYDIQKAVGQLK
                     GEVSQFDGQDSLGAVRVPLKKLSFTNASPLVMWAKLYLINPEQMNLEDQTFSTWQVLQR
                     PVF"
     gene            complement(19507..21354)
                     /gene="aspS"
                     /locus_tag="DS833_RS04680"
                     /old_locus_tag="DS833_04680"
     CDS             complement(19507..21354)
                     /EC_number="6.1.1.12"
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0004812 - aminoacyl-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /GO_process="GO:0006418 - tRNA aminoacylation for protein
                     translation [Evidence IEA]"
                     /codon_start=1
                     /gene="aspS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003547039.1"
                     /locus_tag="DS833_RS04680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_04680"
                     /product="aspartate--tRNA ligase"
                     /protein_id="WP_118896528.1"
                     /transl_table=11
                     /translation="MEKRTNYCGNITAKYIGQKVNLYGWVQRVRNLGNLVFIDLRDREG
                     LVQVVINHDSGQELMHLADQLGNEYVIQVKGEVVKRSSINPEMKTGEVEINAQELIILN
                     KSQNPPFEIKDNIEVGEQTRLKYRYLDLRRPSLQKALILRSKILQATHEYFDKNGFINI
                     ETPILGKSSPEGARDYLVPSRIYPGSFYALPQSPQLFKQLLMGAGFDKYYQLSRCFRDE
                     DLRGDRQPEFTQIDMETSFTDEEQVQEYTEGLLKKVMKDVMGIDLKTPIDRITWTEAMN
                     NYGTDKPDLRFGMKIHDLSPIFKNSDFKVFSNAISAGGFVKGIAVKNGAETYSRKQIEK
                     KQDFIKRFHAKGLAWVKFENGEFNGPIARFLNEENQAALIKEFSLTGGELLVFIADKWK
                     VCCDSLDHLRREFAKETNIIPKHVFNFVWVVDWPLFEYDEGIGRWIAAHHPFTMPDDEG
                     IKLLDTDPHKAHARSYDIVMNGDELGGGSIRIHKRSIQEKMLKALGFSKRRAYEQFGYL
                     LDALDMGFPPHAGLAIGLDRFAMLLAEKDNIRDVLAFPKNANASEPMMHAPAPVAEQQL
                     ADLGIEVEAQYHESVAKIETTLKQQAEETAAKNTSWDEN"
     misc_feature    complement(21453..21473)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.67"
                     /tool="antismash"
ORIGIN
        1 ctcgttaacg gtaaaggaag gcgttttttc ttggtgaaaa ggacataggc caatataatc
       61 cttacctttt ttttcaagtg atacatattg gctgataacg ttcacaatat tgatattttc
      121 tcgtacttta gcaattgttt gctcaggtat taatccagcc acttcatcac ctacaaataa
      181 ctatttaata accaacttac ttaaatcccc taatccagta gctaattctg aaatcaactt
      241 aagctgtgct aagcgattat tcttaactgt ttcatctttg gccataatca tattagtttc
      301 aaaataaaga tttataattg gctgtattcc aacaaagcct tcatataaag ctgtcaaatt
      361 ggtaagctta cttaaattat ttacttcgat aaataactta ttctcacttt cattttcaaa
      421 caagtctgga ttaattatgt tttgcccttt gaattcagct ttctttaaaa tattatttat
      481 tctaattaag ctttcaacaa ctggcttaaa ttgttcatca tcatggtgca attgcaacac
      541 attagctgct gacaaaattt ggatcggatc ttgttgattt gaagctaaca cggcatcaat
      601 aatgtcatac ttaaattgat ttctttgtaa gtattgatta atccgatccc gaataaatga
      661 agcaatctca tcatcttgta gctcagtctt aggtaactta gccgaggttt gaccgtcaag
      721 ttcggttaca atttcaggca aaactttatt aaatggtaaa gaccaacttt gatttaataa
      781 aatacgcact atcccatatg cataacggcg tagagcatat ggatcgtttg atgaattggg
      841 aatcatacct gccgcaaaaa aggtaatgat tgtatccaat ttatctgcaa ttgataaaag
      901 agaaccaaca atagtttgtg gtaattcacc ttcggcagtt gttggcatgt aatgctcttt
      961 aattgcaaca gcgactgttt gtctctctcc agctaaactg gcataatgca tgcccatcac
     1021 accttgcaat tcagcaaatt caccaaccat ttgagtaact aagtcaaatt tatataattc
     1081 actagcccga ttaaaatcag cgattgtttg ttcatctaat tgccatttct cagctaaaaa
     1141 gttaccaatg atgcgaacac gtttgatttt ttctgacatt gaaccaatct tgtcatgaaa
     1201 agaaacatta tcgagttttt gtacaaaatg actaagcgga tattttctat cttcatcata
     1261 aaagaattgg gcatcatcaa gacgtgcaac taaaactttt tcattccctg aaataacatt
     1321 ttctagaaaa tcttggttac cgttacgtac agaaataaaa tgattaacta ggtgttcatc
     1381 ttgatcgtaa acttcaaagt accgttgatt atctttcatt gaagtaatca atacttctgc
     1441 tggcatttgt aagtattttt catcaaatgt tcctgcaaaa acagttggat attcaaccaa
     1501 attagtcact tcctcaagca aactggaatc tggtttgatt ttccaattat tttctttaac
     1561 caattcagac atctgcgtca caatcatttc tttacgttta gttgcgtcaa caatgacaaa
     1621 ttgatctttt aaagcatctt cataatcgcc cgtattagct aatactactg aatcacctaa
     1681 gaaacgatga ccttcagttt tacgaccagc tgtaatatcc aataatttga caggaataac
     1741 ttcattgcca aaaagagata caatccagtg aattggtctg ataaattcaa aatcattggc
     1801 cgcccaacgc attttagtag ggaaagtcat ggccttaact accttattca tgtttaacaa
     1861 aatttcacta gctttttttc ccgttttttt aacatgaaca taggcatact ctacaccttt
     1921 aagttcttca aaataaatat catcaacgga cattccttgc ccacgagcaa aaccttgagc
     1981 agctttagtc caattattat cttgatctag ggcgattttt ttagctggtc cctttttgat
     2041 ttcatcaata tcatcctgct tttcagcaag ttcttcgact aaaatcgtta gacgtcttgg
     2101 cgtagaaaaa gttttgatat tcttaaactt taaaccattt tcatttaaaa attttgtggt
     2161 tttgtcagct agttgattca cactacgggt gacaacatgt gctggcatct cttcggtccc
     2221 aatttcaaat aaataatctt tagtcatttt caagccctgc tttcttatct tctgcactct
     2281 ttaatagcgg gaaacctctt ttttcccgtt cttcgacaaa acaaacagct acttcatggg
     2341 caagatttct aattctcgct aaatatcccg cccgttccgt tactgaaact gctccgcgcg
     2401 catcaagcaa gttaaacgta tgcgagcatt ttaaaatata atcatatgct ggctgaacca
     2461 aatttaattt aattaattcc tgtgctgttt tttcgtaaac atcaaagaat tttaacaagt
     2521 cttcctggtt tgattcttca aaagcatatt ttgaattttc atactctgct tctttaaaga
     2581 tatcacggta taaaacacca ttgccccact ccaaatcaaa aacagagtta acgtcttgaa
     2641 tatatgaagc taaacgttca accccataag taatttcact cattgttggt ttaacttcga
     2701 gttcaccgac aacttgaaaa taagtaaact gacttacttc cattccatca agccatactt
     2761 cccaaccgac accggcacac cccattgaag gattttccca attatcttca acaaagcgaa
     2821 tatcatgctc aagtggatta attcctaaaa cttttaaact atctagataa tattgttgaa
     2881 tatctgtcgg cgctggttta attactactt gaaattgatg atgttggaat aagcgattgg
     2941 gattatcacc ataacgtcca tcagctggtc ttcttgatgg ctcaatatag caagcagccc
     3001 atggctctgg ccccacagcc cgtaaaaatg tatacgggct cattgtacca gccccttttt
     3061 ctacatcata tgaaggcata accatgcagc ctttggatga ccaaaattct tctaatttaa
     3121 aaatcatatt ttgaatgttt aattttttct ttgtcatttt taatcctttc tgcattagac
     3181 cataaaaaaa gcctatgcaa aacttgcata gggacgagat ttaatcgcgg ttccacccta
     3241 attcagggaa aatataccct gcacttaatt attgactaaa ggtgcctttt cccagatgtc
     3301 cttgcactat ctaacactcg cttgactggt acttttcttc ttccttatca ttgtcaaaac
     3361 acaaattaat tttaccataa tccaaggata agctaaagca aactaagtta ataaatttaa
     3421 ctcgtctaaa aatttcttgg tttttaagtt taagtcaatc gttgcctgat aaatttggtc
     3481 aattgctttt cgcgttgctt ttttggtttg agcactaatt gtaatttcac ccaaacgttc
     3541 agctggtaat agcccaattg ttcttaaaac agccgtttct ttaggcttta gatggaggcg
     3601 attagaatca gtataaaaat ggtcgctaca taaaaccccg ccatacttta ttgaataatc
     3661 aaaattgcct ttttctttcc tacaaataac gcagtgacgt agttctggct ttaccccaaa
     3721 tgcagctaaa agttgcattt gaacgatttg agtaatcatt tctgcgtcaa ctccagcatt
     3781 gattttttgc aaagcaaaat cagctaatag gtaatattga tctatatgtt ggtattcaat
     3841 aaaggcatga tcaattaaat ctaaaatgaa agaagaatac gcatttttat ttatatcagt
     3901 aaaaatatga ttaaattgtt tgatattttt ataagttcgt aaattactaa gcccatgacc
     3961 attggtatag ataatgtaag taccgtaaga aaagttaagt aaggctgcac ccaatttcga
     4021 cttgggacgt agtgctccgc gagcaagcat ggtaattatg ccgtaatttt tagttataat
     4081 tttagctaag acatcagctt cattatactt ttgccgttta aaaattattc cttgaacttc
     4141 tttgagttca cgtgccattt ttaggacaaa tccttcttat tataaccaat ctgcttcaaa
     4201 aagcggggat cagatcgcca attacgttga actttaaccc acaagtgcag gttaactttt
     4261 tcacctaata agtcctcaat ttgtttacgg gaattaatgc ctatttgctt aagcattttc
     4321 ccccctttac caataataat ccctttttgc ccactttttt cgacataaat tgtagcttca
     4381 atttgcaact tgttattttc atattgattc atttgttcaa cccatacggc agctgcatgg
     4441 ggtacttctt cggcagttaa atttaaaagt tgctcacgaa ttaattcact aaccataaaa
     4501 tattctggcc gatcggtaat ttgctcagag tcatagtaag ctggaccttc tggtaaatag
     4561 tcatataaaa cttgatttaa gtcagaaata ccaattccct gagtagcaga tattggtaaa
     4621 aattctttaa aaagatttaa ttgacggtat tcatcaatta ttcctaataa gtcgtttgga
     4681 ttaacctgat cgactttatt aattagtaaa aatgctggta ccttaacttg ttgtaaaaga
     4741 ttaacgatat attcgtcacc tttacccatt ttttctggtt caaccataaa taaaattaag
     4801 tcaacatcat ttaaactgga taaacttgct ttatccatat agtcatcaag ttcaccatgt
     4861 ggcttaaata ttcctggtgt atcaacgaaa attacctgca tacttgacgt agtgtaaata
     4921 cctgatattt tattacgcgt tgtttgcggt ttgttagaag ttattgcgac tttttgaccc
     4981 actaaataat tcattaaagt tgatttacca acattgggtc taccaattaa cgcaacaaaa
     5041 ccagacttat ttttttcatt atttgacatt atttacctct gccctcatct aactggtctg
     5101 catataaagg caagccatag ttttttaaaa ttttaccttg aatggcaaac atttcttttg
     5161 cttcgtcagg ttctatatga tcatacccat taaggtgtaa aaagccatga acaagggtgt
     5221 agccaaactc acgctgccaa ccagtaccat attcttcact gtgtcttctt ataacactcg
     5281 gacacatgaa caaatcacca atatcttcac aaaaatcagg atctgctgca aaagcggcaa
     5341 tctcaaactt atcttcaccg tcttcaattg caaaggaaat tacatcagtt ggtcgatttt
     5401 tatcacgata tttataattg attctttgac tacgttcttc attgacaaag ttaatactca
     5461 tttctaaatt attttcttta ccaatttcat ttttagctaa caataatagg tcagtaatcc
     5521 acttttgcca gttacatttt ttatcttgta aaaaatcaac ttcatcatta taagtaatat
     5581 cgattggggt cattaacttt gttctttctt ttcatatgca ttaatgattt tagctacaac
     5641 tggatgtcta acaacatcat tagctgaaaa ctgaataaat ttaatatgac tgataccttt
     5701 taaaatatat tcagcgtcca ctaaaccact acgctggcgt ccaggtaaat cgacttgcgt
     5761 catatcacca ttaacaatca tcttggaatt aaatcctaaa cgagttaaaa acatcttcat
     5821 ttgcgcatca gtagtatttt gagcttcatc taatattatg aatgcatcat ctaatgtacg
     5881 cccacgcata tacgcaagtg gagcaacctc aattactccc cgttccatca aatgatcagt
     5941 cgtattcgta cccaaaatag aataaagaga atcgtaaatt ggtcttaaat atggatcaac
     6001 tttttccttt aaatctccag gtaaaaatcc aagtgactca cctgcttcaa ttgctggtcg
     6061 ggttaaaaca atgcgtgaaa cctcaccctt tttaaaagct gcaattgcgc aaacaacggc
     6121 aatgaatgtc ttaccagtac cagcaggacc aataccaaat acgacatcat ttttttctat
     6181 tgcttcaaca taattttttt gaccgatatt tttcacccta atcggtttgc ctttagcatc
     6241 ccgaattaga atttttttat atagatcagg aaaatattcg gtaatccctt tatccgccat
     6301 tttcattgcg ctgacaatat caggagcact gatattaata ttagcactaa ctacattgtc
     6361 taaggctttt aaaacagcaa ttgctttttg acaattattg ctatcgcctg caagcagaat
     6421 ttggtttcca gtatcagtga tactgatatc atatccctct gctaacaaat caagattgct
     6481 gtcattaacc ccaactaact tttgaatatt ttctggattt ctaggaataa aattggtttg
     6541 agccaatatc ttttctccct ttcttgctta actcagtttg tttttaacta ggttagaggc
     6601 aacttttcca tctgccctac ctttgattct gggcattaaa attttcataa tcttaccaaa
     6661 gtcagcttta gttgcaccat tgacttcagc aattgctgca ctaacgattt tttccaactc
     6721 agattgtgaa agttgcttag gcatataggc ttcaataacg gttaattctt ttttagtctc
     6781 ctcaactaaa tcagtacgct tagctttaac aaagtcagcc aatgattctt cacgttgctt
     6841 tttttcacga tttaaaactg ttaattcttc atcggaattc aattcacgcc ctaatttgat
     6901 tttttcgttc attaaagcag ccttaatcat ccgcacagtg ttcaacttaa ctttatcatg
     6961 tgccttcatc gcatctttca tatcagccat tatctgttct gataaactca cagtaatccc
     7021 ttctttctaa atatagcttg cctaaattat aacaaatctt gttataggta taaaataaat
     7081 attcttagta aaatatctaa aaaacgacct ctatcataat agatagaagt cgttttttta
     7141 tattaataat gcttacgctt gcgagctgct tctgacttca gctttctacg tacacttggc
     7201 ttctcataga attcgcgctt gcgatattct tgcaaagtac cacttctaga aacggaacgt
     7261 ttgaaacgac gaagagcatc atcaatagac tcgttttcgt gaacaacagt cttggccata
     7321 tgtgatccct ccttccattt cttgacgttt ccgtcataca tttatttaaa ttatatcaaa
     7381 ccatattcat cggtcaatac atacaagcaa tatttttaaa attatttttc attaccgttt
     7441 tagctattta aaatctgtta atattaaagg aagattgtat aataaatgaa aaaaggagca
     7501 gacaatgact gacgaaaccc caaaaaaaga agttaatatt ataattattt ctgattctgc
     7561 tggtgatact gcttttaata atgcagtggc agcagcagcg caattccccg atgctcaaat
     7621 taactatcga cgatatccat tcgtttataa taaagaaaaa ttggcagaaa cttttcaaga
     7681 aatcgaaaag tatcctaatt tggtaattat ctatagttta gttaaagatg aaatgcagtt
     7741 accagtaatt cgttttattc gggaacataa tatccatggg attgatatct tatctccagt
     7801 ggttgaagca attcaaagtg ctactggtag ccgaccgctt aagaaaattg gtgcccaaca
     7861 taaaatgaat caaaaatatt ttgatcgaat atctgcaatg gagtttgccg taatgtatga
     7921 cgatggcaaa gatccaaagg gctttttaga agctgatgtc gttttattag gtgtttctcg
     7981 aacttcaaaa acaccactct ctttattttt agctaataaa aatttaaaag tagctaactt
     8041 accattagta ccagatacgc acattccaaa ggagatatat caagttaatc ctaaaaaaat
     8101 tatcggtctg accaatgact tatccgtatt aaatgaaatt agacggcaaa gaatgattgc
     8161 ctatgggtta aatcccgata ccacttattc aaatacagac gcaattaaaa aagaacttga
     8221 ttctgcccaa acgctttata atgaactggg gtgttttgtt attaatgttg ctaaccggtc
     8281 aatcgaggaa acggctgcct tgattttaga tcatctggga attgaagaat aaacaagcat
     8341 ttaagaccgg tcttaaacat tttttaccta agtctggcaa gatgaaatga ggtcaataaa
     8401 atggcaaata caaataagga taaaaaacaa aattttcaaa aagccatctt tgctgggggc
     8461 tgcttttggt gtatggtaga gccatttgac actttacctg gtgtcaaaaa ggtgatttct
     8521 gggtataccg gcggtcacgt ccctaacccc acttacgaac aagtagctag tggattgact
     8581 gggcacacag aagcagttga aataacttat gatccagagc tgatgtctta tgaccaatta
     8641 ttagaatact attggcaagt aactgatcca actgatgcca tgggccagtt tcaagatcgc
     8701 ggtgataatt atcgcccagt tatttattat aattctatcc aacaacagtt agctgccgaa
     8761 aaatcaaagc agaagctcca agaaagtggc agatttactg caccgattgt taccaaaata
     8821 gaaccggctc aaccgtttta tccagctgaa gaatatcatc aagatttcta taaaaaggcc
     8881 cccaatcgct atgcgctaga ggaagctggt ggtcggttaa cttttatcaa agaacactgg
     8941 caaaaataaa attaactgaa ttttctcagt tggttacctt cccaactttt gttacactga
     9001 attaaatgaa ttactattat ttaggacaaa aggaaaatgt gaataatgga tcgactcgat
     9061 acctttaaca gacgttataa tttactttca aagatttcag cttcattttt ttattcaatt
     9121 gcagtagcaa ttgcgttaaa tcttttttgg ggtccggggc acatgtattc ttctggtatt
     9181 accggatttg ctcaattaat taatacattg agtgaacgtt atctcccctt cactttgaca
     9241 acttcggtaa tgtattttgc cttaaatgtg ccactacttt tagttgcttg gtttaagatt
     9301 gggcacaagt ttactttttt tacaattatc acagtaattt tgggctcaat tatgatgcgc
     9361 gtgctacaac cagttaatat gcatgttgat ccccttgttt gcgcaatttt tgggggaatg
     9421 attaatggct tgggaactgg ttttgccttg aaaaatggca tctcaactgg tggcttagat
     9481 attgtgggaa ttgttgttca ggaaaaaaca ggcacaagtt atggcaaggt aagtattttt
     9541 attaatttag taattattgc tgctgccggt gttgcctttg gctggaatcg tgctttatac
     9601 tcggccctga ctatttttat taatggacga gtgattgatg ctgtctatac ccaacaccaa
     9661 aaattgcaag tcacaattgt cacagatcag ccacaagcga ttattgatgg aattcaagaa
     9721 aaaatgcatc gcggcatcac aatttttcat gatgtcgaag gagcgtacag tcacatagaa
     9781 aaaaaagttt taataacagt tattaatcgc tatgatatgt acgatgtttt acaaattgtt
     9841 caaaaaaatg atccctatgc cttcatgagt gtcaccgaag tagagcgtgt ttatgggaca
     9901 tttaaagaac aagaaattgt ttaaaatata tctatatttg ataccacaaa agccactcca
     9961 tgataaatgg aatggctttt tagttatgtt aattaaaaaa ttatttactt cttagaagtg
    10021 gtagccaagc attccaggta tgttgcttaa tatctgttaa aagtagcagt aagccactgc
    10081 ttccagtagt taaatctaaa gaacacttaa aaccaaatcg accaggtacc attacgcagc
    10141 cattttgagc aactaagtaa ttattaagta aattgtactt cttctttaaa gtaactttat
    10201 tattggtaca aattgcaaag gcattatcta aaatcagcag gctaagaaaa ccatcgaata
    10261 atccggcaaa aaaagttaca aaaacatcat tttgctttaa tatttttaat aaaatttcta
    10321 attctttttt ggtaaaaacc ttaggatcat cttgtaaaaa ttctatcatt aataaagcta
    10381 agcccgcact accatgatta acatacggga ttaaacgttc atatgagtag gaattatctt
    10441 taataaatgc accgtcactt gtaagttgta atgaattttt tattactacc tggtagattc
    10501 ttaaagctgc ttgcttatat tgctttgcct ttgtaacaat acttaatttc cataaaaata
    10561 atgctacacc caaccagcca gtaattaatc cactatcagt tttttcggta tagcgttcat
    10621 gcttaatgat ttgcattact tgtttaccaa gatcaattgc attttgtaag taaatagttt
    10681 ttttggtttg tccataaaag cataaaaaag ctagcccaac tccggctaaa ccagagtaaa
    10741 ttgaaatgtc attggttaac ttaagtgcca cattagtttg tatttttttc attatactgt
    10801 aactaatttt agtgtagcct tgttcatata aaacagtagc aataccgctt aggccagtaa
    10861 ataatccgat atctgttgtt ggctcagcta acaacttttt taaatttggt aattgctgtt
    10921 cgagccaaat attaatttct tgcttacttt tctgatctaa agtctgtgat ctatttaaag
    10981 ccattatagc gccaaaagca ccattggcca cggaataata actaatttca gaactatatt
    11041 gtggaatatc accataaatt aatcctttaa agttgtaatt caagttgtcg ctgattccct
    11101 tagctacttc ggcaatattt tgatttaact gattcagtga aaatggtgta gacggtactg
    11161 ttagattttg ataataatac tgcgggtggc gtgagtcaga attaaaattc aaatttaatt
    11221 gcttttttaa attatgcaaa aattctacaa tttgcttacc aaactcattg ctaatattct
    11281 tatcttgcac ggcttctaat tcaggcgccc aatcaaagcc agttgcggtt ggcaaaatca
    11341 gataacgtgc tattttgtat aacgcaattc gatcagcttc tgcaaaagtc ttcgcattaa
    11401 aatcagaata gccaggcgtt gccagaccag gattgtaggc tgctgaagct ttttgagcat
    11461 tttcaaaatc aattaatttt actttatccg tgtctaatat aattatatta tccggttgta
    11521 aatcaccaat tgcgattccc ttttggtgaa tttggttaat tgcctttaaa agtgccgtaa
    11581 taattttgac cgtcttcgta agatattcat ttttcttttg cttatttgcg gtaaagggat
    11641 attgactatc aacaaaatca gctagagtat ctccttgaag atattcttca actaaatatt
    11701 gatgtttcca tgccttaaaa ctttcataaa catcaacaac tgttggtatc tcagctagtt
    11761 gttttaatat cttatactcg tgtttaatcc gattaaaacc atcattgcca ttagcatcta
    11821 agcccgcaaa agcacggcct tcctttagaa cccattcctt acccttgaaa actgcatgat
    11881 aaactccacc agcattgcta tagtgcaaag aaaaatcaac attataattc attagttttt
    11941 tgaattcatt ttgatcataa tgttgcacat tatttttcaa ttgttcaggt tctacaataa
    12001 aatcaggctg ataataatat ggtaaccgtt tatcttcaac taagttatgt ttattatcaa
    12061 taatggcgta aacttctgca ccgtcaatca ccgttttcat tgccttaaag gcaccgtaac
    12121 ggtaaaagac atggctatct tgccattctt gatcgcttaa tatatatggc ccctctaaaa
    12181 agtcttgggt gatttttgct aacgcaggca aaagttggac aaattcagca gtatttacgg
    12241 gataaactgt aataaacttt cccgactctg ttcggtcacc atatttggaa ttacttaaaa
    12301 gcattgcatc tactgtatca ataaatttat aactaacttg ttgattattt aagtactggc
    12361 tcacagtcaa taatagtttt tgtgcatcct taatattagc agttagatga attttccagc
    12421 cttgttgggg caatttatga tcaaataaaa tataatgcca atagctatca gttgattctt
    12481 gaaagctagt tttaggtttt ataaatttaa atttattttt tggttcatca ttgggataat
    12541 aaaaaagtga acggtcgttt ttaacaaatt ccatgtattc attaccagtt aagtccattt
    12601 atctgttttc tccttttaat tatttttcaa ctgctaatat ttcttcatta acaaattgtt
    12661 tatatttagg aaccaattgc atcaactctt ggtgagtacc actgccggta atttgatgat
    12721 tatctaaaaa ataaattttg tctgaatcaa caattgtcga taagcgatga gcaatgacaa
    12781 ttaaagtcgt ctggtgagta gcaatcaact cattcaaagt attagtaata attttctccg
    12841 aattgggatc taggttagaa gttgcttcat ctagaattaa aaaattggct tggcgcaagt
    12901 atgcgcgagc aatctgtaat ctttgccttt gaccacccga taaaccaatt ccttgttcac
    12961 caactaaagt ttgtaagcca ttgggcattt tttgcacatc ttctaacaaa ttagccttgt
    13021 ccagagcggc ccagatgtca ctttcttcag gaatagcagt caaaccaaac gttaagttta
    13081 aataaattga tcctgaaata atcgtgtttt cttgggttac tacggcaaac aaattacgcc
    13141 aagtatttag atcatagtta gtagcactta ctgaatttaa taaaagttgt ccttcattta
    13201 attcatacaa tctagttaat aaattaataa ttgttgtttt accagcacca gagggaccaa
    13261 ctattgctat tttttggcca ctattaaaac ttaaagaaat attttgtaaa accggttcct
    13321 tttgatatga aaaagaggca tttttcaacg ttaaacaact attcttagca aacaatattt
    13381 gagaattaac ttgataaaca cttttttctc ctggtgtatt caaaatctta tttaattcca
    13441 aagtagctcc tttagcttgc ttgtaactgg tataaaaatt acccaacata ttgattggct
    13501 caattacctg aaagagataa attaaaaagg atactaaggt gccaatactc aaactagcct
    13561 gttgtacacg aataccacca taaataataa ttaaaagaat aattcctaaa gtaaaaactg
    13621 tttgaatggg acctacaatt gaaaatatgc gatcagtttt atttgaaact ttaaataatt
    13681 caactactac ctgcttaaaa tttaacaaga ctgggcgata agcattattc agcttaatac
    13741 tgcggatatt atatatgttt tctgtacttt gaccagaaag ttcacttaat ttattctggg
    13801 tagtgagcga caatttttca ctaatttttc caattggata tgcaattaag ataattagtg
    13861 aaaaagataa gacaataaat accgtcaatt gccaatctaa atgaaataaa acaatgaatg
    13921 atcctagcac tgcaattaaa ctattaatgg tggctggaat actactagtc atgaagcttt
    13981 gaactacttc agcatcatta attaaatgac tagaaagctg accacttttt tgattagtaa
    14041 aaaagctcat aggcaaagta agtaactttt gctcaatttc cattctgact tcagcaattt
    14101 tcaaatttcc agctacacta attagatatt ggcaaaaagc actaataatt gcactaaaaa
    14161 taatggtaac cacgattacg gcagctaaac gaaaattgat atgtgcactt atgtgcgttt
    14221 taccatcaat aaattgccgc actattaaag ggatcaaaac ctcaataaag gtaccaaaaa
    14281 tacctaaaat aagccctaaa atgaactgcc aagaaattgc atacagcttt attttcttat
    14341 tcataaatct cacattcttt tacaattaat aaagacatat ctcatgacca aagatatgtc
    14401 tttattaatt tatttactta aaatatacca aagaaagtat gcccgcaaat taacgacttt
    14461 cgttttttat tattgtattt actatgtttt tgatgcttga ccttcttctt ttgtaggcca
    14521 aaaatatgcc gcattaatga atccatggaa tcgcttcctt tctttactat atgataacta
    14581 cataataaca tatttaagaa aaaataaaat attttttctt actttttcaa aaaaatacct
    14641 tatttcttga attatttata attgatgtac taatttgatt aaaaagctga tacttgccac
    14701 tatataaaaa ctcactggtc tcttttaatt tctaagactt ttaagtcttt agcaatttta
    14761 gcttctagtg tagcgatgtc ttttttatct tggaccaata atctatcgat ttcagttaaa
    14821 tcaatttttt tattttcaga agtagtaata tattgtgaaa catttaaatt ataatcatta
    14881 gcacggattt cttcgatgga agctaaataa gcatattgtg gcacagctac acgtttttga
    14941 taggtcttga aaattttatc aatgttttct tgagttaaat aatttttcat tttaccttta
    15001 gcaaattctt ttgaagcatc aataaaaaga atatctttgc tagtacgcgt cttttttaat
    15061 accaaaataa tcattggcct tatgccctca taaaatagat taggcggtag ccccattaca
    15121 gcatcgatct gattaccatc tggatgctca accaaatttt tgcgaattat agcttctgca
    15181 gcactacgga ataaaacttc gttaggaaga acaatcgcca taattccctt ttcgtttaaa
    15241 tgataaagac cttgtaaaac aaaagcaaaa ctagccttag ttcggggagc caatttacca
    15301 taattacgaa aacggggatc cgttaactta ttttggttat tgtcccaaga ttgaggatct
    15361 ggtggattag ccacaaccgc atcaaaggta cgtggatgag caatttcttt agtatttggt
    15421 tcggctggcc aatcgttttc gagcgcatca gtgttgaaca atgtcatatt agtaaataaa
    15481 acatggtgca acattaaatt tattctagct aaattgtaag ctgtcaaatt tgcttcttgc
    15541 ccatacaatt tagcaattgc tgagttatta tcatttgcta ttgctgacaa aattgaacct
    15601 accccacaac taggatcata tactgtgaac gattgggttg ctttaggtaa atctgctgtc
    15661 actattttag ctattaattt tgcaactgcc ggtggtgtgc aaaaagtagc ctccttctta
    15721 ccagctgcat atttgctaat taaaccagta gagatatcac caagaatatc tttaccagct
    15781 tcatcttgat aatcaatact atcaactaat ttgacaatct tcgctaaaga cttcactcgt
    15841 tcattagctg atgaccccag gtaggaatcg gctaagttaa gattactaaa gatcccctta
    15901 aaggtttgac ctgctgcttt agatagtgca gcattcttat caaaattagc aaaaatagtt
    15961 tgatagtcac ttagatttac ttggcccttg tcaattttat ttactaatga ctgccaagtg
    16021 tcaagtggcg caatggcata accaagattt gaaaagatat ccttaagata agcatttaat
    16081 tcagcaccgc ctgcttgttc taggtaagct tcattaattg cttggccttt cttaacattt
    16141 atagcactgc tactaacaag atactgttct tgctgttcgg acaagtaacg ataacatatg
    16201 aaggctaaaa tataattttt ggattcagtt gtatccgtat tagtctctag ctcattggtc
    16261 agtgtccata actgggaact aattgtctgt aattttgtca ttattcttcc tttctcatgt
    16321 acccatttag cgcaatagta cttttgcttt tgaagatgga ctatttgcta ttgcctcata
    16381 ctaattagct tatcaggctt ttagaaaatg ttaaattaag agagctaaaa ataaaaaagc
    16441 atctaattta ttaaataaat caatttgctt ttttatactt tacataatta ttattattta
    16501 aaaagtttgc gatattcgcc atatccttct ttttctaatt gatcaaaagg aataaatttt
    16561 aaggctgaag aattaataca ataacgtaag cctccttgat ctacaggacc atcggtaaag
    16621 acatgtccta gatgagagtc agcctcagga ctcttgacct cggtgcgttc catattatga
    16681 gactgatcac gatgataaac tagtttttga attggcttag taaagctagg ccacccacaa
    16741 cccgcatcgt atttgtcttc acttgaaaat aacggttcct tagaaacaat atcgacataa
    16801 attccctttt ggtaaaaatc atcatattta cccttaaaag gataatcggt agccccatgc
    16861 tgcgtcactt cgaattgctc tttggacaaa tgctttaatt gctgcttttt ttgttcttga
    16921 tccattattg tcactctcct taaataacta tcataaatct atttttgaac aaccgaaaaa
    16981 ttaattgcta aattaatatt aatttaaata ttcttaaagc gactactgcg ttataattgt
    17041 atctatatca aaattcaaga aaggttcttt tattatgcca actctagcaa ataatttatc
    17101 tgatacaatt aacagaagga ttgaaaaatt acctaaatcc gaaattcgtt catttagtca
    17161 aaaaatatct caaattcctg gaatagttaa gttgactgtc ggtgaacccg acttgaacac
    17221 tcccgaccac attaagcaag ccgctataga tgatattaac cgcgatgact cacactatgc
    17281 gccagaagct ggtaaagaag aatacttaaa cgcagtaagt gattatctca aaaagagttt
    17341 aggtgtgtac tataacccca aaaatgaaat ttgtgcaact gtcggagtat cagcagcctt
    17401 aaatgtttct tttatggcta tccttaaccc cggtgataaa gtaatcgttc ctacacctgt
    17461 ttggggagtc tattttggta ttataaaaat ggctggcggc gtacctatag aagtagatac
    17521 ttctgctgat aattttattt tgactgctgc acatctagca gaagttatgg aaaatgaagg
    17581 aaatggggca aaagcagtta ttttaactga tccatctaat ccgaccggac gagtttatgc
    17641 taaaaaagat ttaaaagagc tagcaaaagt tattgtcgat tataatttat ttgccttaag
    17701 cgatgaaatt tatgccgaat taatttatgc tcagaaaaag cactattcgc ttacacaaat
    17761 tattccagat cggactatcc ttctttcagg attatctaaa aattttgcca tgactggttg
    17821 gcgaattggt tatattgcag cgccaaaaga aattatgcaa acaatctcca aaatcaattc
    17881 ctttatgatt acctcagtta ctgataatgt tcaaattggg gcagcagaag ctatcagtca
    17941 tggtgaacaa gattatatcg aggcccgcgc aatttatgaa cgcagattac acataattca
    18001 aacaggtctt gaaaaaaatg ggtttacaat ggctacacct gaaggtgcat tttatatttt
    18061 tgctaaaatt ccaagtaaat tcggtacgga tgatgtcgct tttgctactg acttagccaa
    18121 taaagttaag gtaggagtaa ttcctggtag ttactttggg gctggtggtc aaggatttgt
    18181 acgtttatcc tatgcatcat ctgaaaaatg tttaagaact gccgttgagc gcattacaac
    18241 ttacgtaaat gagcagcttt aaataattag caagcatttt attttggtcc agttcagtag
    18301 atagtttaga ctttagagta aacagtttta aagaaagagt aaacaaaatg caaattacaa
    18361 gactaagtac cccattatcg actaatggtc aaccaccaaa agttggcgag atattacccg
    18421 atttaaaagt tgaaaaagct gatggatcta tcgtcaactt gtcagaatta attaacaaac
    18481 ccactttaat tagcgtagta cccgatatta atactagtgt atgtagcatc tcaaccaagc
    18541 gctttaatag tgaagttgac aaatacgaca atattaattt ttataccatt tcaactaact
    18601 cacctagtga ccaacgtaac tggtgtgcag cagaaggagt agtaaaaatg gaattactct
    18661 ctgatgaaaa atttgatttt ggtaagaaga tgggactatt tattgaaaaa atgggacttg
    18721 attcacgaag tatttggatt gttgacacta accaaaaaat actttatcaa gaattaattg
    18781 tggaaatgac gaatgaacca aactatgatg cagctttagc atttttagat actttaaatt
    18841 aagcaaagaa aaaggcaact aggtaaaata ctagttgctt tttgtttaaa atcttgttta
    18901 aaaaactggt cgttgtaaaa cttgccaagt agaaaaagtt tgatcttcta aattcatttg
    18961 ctcaggattg atgagataca atttagccca cataactaaa ggagaagcat tggtgaaact
    19021 gagctttttc aaaggtacgc gtactgctcc taatgagtct tgaccatcaa attggctaac
    19081 ctcacctttt aattgcccga cggctttttg gatatcataa aaaacgcaga agtgctggtt
    19141 aaaatgccaa ttttcatagt cccaaggata tttaaatgat gtaatcccta attgttgata
    19201 aacttgaact aataagccgg tctcttctct tatttcccgt agtatagctt gatccagccc
    19261 ctctccatcc tctaaactac cacccggtaa atcataacga ttagtgtatg ggccaccatg
    19321 ctttttaatg acaacaagtt cggactgatt tccaattatt ccataacagc caaaggcgta
    19381 atgatatttt ctaagcattg ttttgtttcc aatcttttat taaacacatt ataaaaataa
    19441 gccacaaaac tagaagatta catcaagcag tcagttttgc ggcttatttt tctttaaatt
    19501 tatctattaa ttttcatccc aagaagtatt tttagcagca gtttcttctg cttgctgctt
    19561 aagagttgtt tcaattttag ctacactttc gtgatactgt gcttcaactt cgatccccaa
    19621 gtcagctaat tgctgctcag caaccggagc aggtgcgtgc atcattggct ctgaagcatt
    19681 agcattttta gggaaggcca agacatcacg aatattatct ttttctgcta gtagcattgc
    19741 aaaacgatct aagccaatag ctaacccagc atgtggcggg aaacccatat caagagcatc
    19801 taataagtaa ccaaattgtt catatgcccg tcttttacta aaaccaagtg ctttaagcat
    19861 tttttcttga attgaacgct tatggatacg aattgaacct ccacccaatt catcaccatt
    19921 catcacaatg tcataactac gagcatgcgc cttgtgcgga tcagtatcaa gtaatttaat
    19981 tccctcatca tccggcatag tgaatggatg gtgagccgca atccaacgac ctatgccttc
    20041 atcatattca aataggggcc agtcaactac ccaaacaaaa ttaaagacat gcttaggaat
    20101 gatattggtc tctttagcaa attcccggcg taaatgatct aatgaatcac agcagacttt
    20161 ccatttatca gctataaaga ccaataactc accacctgta agagaaaatt ctttaattaa
    20221 ggcagcttga ttttcctcat ttaaaaagcg tgcaattggt ccattaaatt ccccattttc
    20281 aaatttaacc caagctaaac ccttagcgtg gaaacgttta atgaaatctt gctttttctc
    20341 aatttgcttg cgcgaataag tctcagcgcc atttttaacc gcaatccctt taacaaaacc
    20401 gcccgcacta attgcattag aaaatacttt aaagtcacta tttttaaaaa ttggacttaa
    20461 atcatgaatt ttcatgccaa agcgaagatc aggcttatca gtaccataat tgttcattgc
    20521 ttcagtccaa gtaatgcgat caattggcgt ttttaagtca atccccatta catctttcat
    20581 aactttcttt aatagtcctt cagtatattc ttgcacttgt tcttcatcag taaaggacgt
    20641 ttccatatca atttgggtaa attctggttg acgatcgcct cttaaatcct catcgcggaa
    20701 gcatctagat aactggtagt acttatcaaa acctgctccc attaacaatt gtttaaataa
    20761 ttgaggtgac tgcggcaaag cgtagaaact acctggataa atccgcgaag gaactaaata
    20821 atctcgtgca ccttctggtg atgattttcc taaaattggt gtttcaatat taatgaaacc
    20881 atttttatca aaatattcat gcgttgcctg taaaattttt gaacgtaaaa taagcgcttt
    20941 ttgtaagctg gggcgccgca aatctagata acgatatttt agcctagttt gctcgcctac
    21001 ttcaatatta tctttaattt caaaaggtgg attttgtgat ttatttaaaa taataagttc
    21061 ttgcgcatta atttcaactt ctcctgtttt catttctgga ttaatgctcg aacgcttaac
    21121 tacctcacct ttaacttgaa taacatattc attaccaagt tgatcagcaa ggtgcatcaa
    21181 ttcttggcct gagtcatgat taatgactac ttgaactaga ccttcacggt cacgcaaatc
    21241 aataaaaact aaattaccta aattacgaac tcgttggacc caaccatata gattaacttt
    21301 ttgaccaata tatttagcag taatattacc acaatagttt gttctttttt ccataatttt
    21361 aatcctttaa atgttctaag actgaatgca tatttgctaa atcacttaac agcaaatcaa
    21421 ttttttgtcc atcagctaag cgtttaatat tcaacttacc ctcggctatt tctttagctc
    21481 cgatagtaat tacatatttg gccttaactc gatcagcttt tttaaattgc gcttttaact
    21541 tcttttgatc aacgtcatat tgaaccctaa aaccttgctt acgtaacaaa cgagcaattt
    21601 caacaacttt aatctcagtc tcttcaccaa tattagtaat aaaaaaatca attccttgat
    21661 cagtaaataa gcctgggttt tgtttttgca aaactagcat taagcgttct tcaccaatac
    21721 caaaaccaac tgctggggtt gcaggaccat caaattcttc aactaggtgg tcataacgtc
    21781 caccaccaag aatcgttgta gccgattccc ataaactagc atcttcaacc ataaattcaa
    21841 agataatccc ggaataataa tctagccctc taaccaaatc attatcaatt acataatgga
    21901 tatctaactg gtccagcatc tgaataattt gattaaaatt atttttagaa gcttgatcta
    21961 aataatcaat aatttttggt gcattaggta aaaattgctt atcttgttca tctttagaat
    22021 ctaaaattcg gagcggattt ttctctaaac gtcgtttaga atcatcggaa agccggtctt
    22081 ttaagggcgt aaaatagtca actagtgcat catgataact ttgacgcact tgactattac
    22141 ccaaggtatt aatgtgtaat tcataatttt taacaccaag tttagccaat aaatcgttag
    22201 ctagaacaat ggtttcaaca tcagctaaaa aactacttga gccgaaactt tcaataccaa
    22261 tttgatgaaa ttctcgctgc cgccccgctt gcgggcgttc atagcgaaag gttgactcaa
    22321 tataataaac attaaatggc ttagccattt ctggagcata aagcttgtct tcaacatatg
    22381 ctcgaacaac gccagctgtt ccttctggac gtaaagcaat gtgacgtcca cccttgtcat
    22441 tgaaatcata catttctttt tcaactacat ccgaagtttc accacttgat cgagaaaata
    22501 cctcatagtt ttcaaaactt ggtgttctaa tttcttgata gtttgcctgt ttgaaaaaat
    22561 cacgcaatat ttgttcaact ttttcccatg aactagat
//
