LOCUS       NZ_QOCT01000001        28304 bp    DNA     linear   CON 18-SEP-2024
DEFINITION  Lactobacillus bombicola strain L5-31
            L5-31_S84_L001_R1_001_84__paired__contig_1, whole genome shotgun
            sequence.
ACCESSION   NZ_QOCT01000001
VERSION     NZ_QOCT01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lactobacillus bombicola
  ORGANISM  Lactobacillus bombicola
            Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
            Lactobacillus.
REFERENCE   1  (bases 1 to 124406)
  AUTHORS   Motta,E.V.S. and Moran,N.A.
  TITLE     Genome sequences of six Lactobacillus spp. isolated from bumble bee
            guts
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 124406)
  AUTHORS   Motta,E.V.S. and Moran,N.A.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-JUL-2018) Integrative Biology, University of Texas at
            Austin, 2506 Speedway, Austin, TX 78712, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC NGS Cell v. 5.5
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 124.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003515825.1-RS_2024_09_18
            Annotation Date                   :: 09/18/2024 04:05:41
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,612
            CDSs (total)                      :: 1,555
            Genes (coding)                    :: 1,521
            CDSs (with protein)               :: 1,521
            Genes (RNA)                       :: 57
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 34
            CDSs (without protein)            :: 34
            Pseudo Genes (ambiguous residues) :: 0 of 34
            Pseudo Genes (frameshifted)       :: 12 of 34
            Pseudo Genes (incomplete)         :: 20 of 34
            Pseudo Genes (internal stop)      :: 12 of 34
            Pseudo Genes (multiple problems)  :: 8 of 34
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:28:05
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 53209
            Orig. end                         :: 81513
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QOCT01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..28304
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..28304
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28304
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:18304](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..18304)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(368..844)
                     /locus_tag="DS833_RS00290"
                     /old_locus_tag="DS833_00290"
     CDS             complement(368..844)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006352500.1"
                     /locus_tag="DS833_RS00290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00290"
                     /product="hypothetical protein"
                     /protein_id="WP_090093957.1"
                     /transl_table=11
                     /translation="MAGFYLILEAIMLGYACYSWYWQANIDLKGQYRFSSIIWSLIFIW
                     LGFSWQLIEKNDQGLTVFLASFILIGIIDGFTGFGAKKVVVAGYFKRTISYADIDLITL
                     IRVPNPKKKQVICILTTNQNRQYYLRFAQSIAKIVGTIKSHVNHDIRIEIQDII"
     misc_feature    complement(939..952)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 25.18"
                     /tool="antismash"
     misc_binding    973..1211
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
     misc_feature    1157..1172
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            1269..2282
                     /gene="asnA"
                     /locus_tag="DS833_RS00295"
                     /old_locus_tag="DS833_00295"
     CDS             1269..2282
                     /EC_number="6.3.1.1"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004071 - aspartate-ammonia ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="asnA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011162553.1"
                     /locus_tag="DS833_RS00295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00295"
                     /product="aspartate--ammonia ligase"
                     /protein_id="WP_118895783.1"
                     /transl_table=11
                     /translation="MTLIIPQNYQPTLTIRDTEAAIVFIRERFQVLLGQKLNLQRMSAP
                     LFVEKNTGLNDNLNGIERPVDFDVKAFPKDDTIEIVHSLAKWKRLALKKYHFGMHEGLY
                     TNMNAIRRDEDLDNFHSIYVDQWDWEKIIAEDERTITTLTETVAQIFSAIKQVETECAA
                     RYPASTYHLPDDVFFITTQELEDRWPDLSPEERENKIAEQNKAVFLMKIGDNLARSSKP
                     HDGRAPDYDDWQLNGDLIFWYEPLKQKLEISSMGIRVSPQSLHKQLIQANCLAREQLNF
                     HQMLLNGELPFTIGGGIGQSRLCMLLLGKAHIGEVQASIWPKEMLEKCQAHNIQIL"
     gene            2397..3101
                     /locus_tag="DS833_RS00300"
                     /old_locus_tag="DS833_00300"
     CDS             2397..3101
                     /EC_number="2.3.1.286"
                     /GO_function="GO:0034979 - NAD-dependent protein lysine
                     deacetylase activity [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006352501.1"
                     /locus_tag="DS833_RS00300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00300"
                     /product="NAD-dependent protein deacylase"
                     /protein_id="WP_118895784.1"
                     /transl_table=11
                     /translation="MIVTKQIKTLKAEIEQANYVTFLTGAGVSTPSGIPDYRSKNGIYN
                     DSIEKPETILSAETLYHRPELFYHFVLNNMYFPDAKPNIIHQKIAEICNNKGHLVTQNV
                     DSLDLKAGNQQVTQFHGNLYQLYCTKCQQAVKYSTYAQSYLHHNCGGIIRPQIVLYGEN
                     INSQNLTTSIQAIQKADLVIICGTSFVVYPFAQLLAYCQTNAKIWAINKTAIPLAGIAA
                     ITGDALDVFKQI"
     misc_feature    2428..2443
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.33"
                     /tool="antismash"
     gene            3226..3990
                     /locus_tag="DS833_RS00305"
                     /old_locus_tag="DS833_00305"
     CDS             3226..3990
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03716.1"
                     /locus_tag="DS833_RS00305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00305"
                     /product="TerC family protein"
                     /protein_id="WP_118895785.1"
                     /transl_table=11
                     /translation="MSIIKMYAPFFNANNWLHVLTNVNDWLIILTLILMECLLSVDNAV
                     VLAAQTKSLPDKKQQEKSLFYGMWGAYIFRFIVIGIGTYLINFWEIKLAGSIYLFYLCS
                     KFFYDRHHYSADKEGGQVPKTTQRHQNNKRFLSPFWRTVISIEAMDIVFSIDSVLAALA
                     VSSNPVVVLIGGMIGILCMRGVAEVIIKLMDIIPELQPMAYILIGIIALKLLVSLPPLH
                     YELPNSIFAALVFGILLITIAFHFLHSNNHSH"
     gene            4124..4765
                     /locus_tag="DS833_RS00310"
                     /old_locus_tag="DS833_00310"
     CDS             4124..4765
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007127035.1"
                     /locus_tag="DS833_RS00310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00310"
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="WP_090093963.1"
                     /transl_table=11
                     /translation="MDYSTYFTKSTTEKISIDLLGRPLIFDNGQQILGGYIVETEAYLG
                     KRDRAAHSYQGRRTAANEGLYRRGGTIYIYAQRQYFFFDIATQKAGEPQGILIRAIEPA
                     WGIKQMITNRSGKSGPLLTNGPAKMMQAFGIHNKDWNLHFLSKSPFTIDLNDNHKNYAR
                     KIIASPRIGINQSSPAWASKPLRYYVSGNPYVSRMKIKDYQPNNGWKLLS"
     gene            5145..6764
                     /locus_tag="DS833_RS00315"
                     /old_locus_tag="DS833_00315"
     CDS             5145..6764
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013436962.1"
                     /locus_tag="DS833_RS00315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00315"
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="WP_118895786.1"
                     /transl_table=11
                     /translation="MKSRYKWITAVMIAIISMTFGLNCNSNSVNAKKDSNVLKVAMEAN
                     YQPYNWTQTNAANGAVPIDGSQHTFANGYDVKIAKIIGKKMHRKVVVLKTEWDGLLPAL
                     TSGKADLIIAGMSPTAERAKAINFSQPYRRGTFVVITKPNSKFAHAKKLTDFKGAKLTA
                     QQGTSHYGLIKELPGAKRQTAMRDFAAMRQSLISGTIDGYLAEDTEAISFKLVDPDVTA
                     VAISKMAGFHVSKEESETAIGIAKPNKSLLKQVNQILATIPTATRNKMMTAAIKEQPKA
                     DDNKKGQSENWFISMWKQYGSMLVSGIGMTLLLASVGTIAGFFIGLAVGIIRTIPTPTT
                     TGKKLLLKVSNWLLSVYIEVFRGTPMMVQAAVIYYGIAQFWHLNINRTIAALIIVSINT
                     GAYLAEIIRGGIISTPTGQFEAASALGMTHNQRMWHIILPQAIKNCLPSITNEFIVNIK
                     DTSVLSIISVSELFFVGTTVASQTFKFFPTYLTISAIYLILTFTITRIFNLIEKHLQGN
                     KNYNLMANQVQVGTTNDMEVKK"
     gene            6764..7510
                     /locus_tag="DS833_RS00320"
                     /old_locus_tag="DS833_00320"
     CDS             6764..7510
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007127037.1"
                     /locus_tag="DS833_RS00320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00320"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_118895787.1"
                     /transl_table=11
                     /translation="MTTTSETILSLKHLQKSFGEHQVLRDISLDIKRGEIATIIGPSGG
                     GKSTTLRCINLLEEPTSGEITFHGENVLASYNRNIYRAKVGMVFQQFDLFENKNVLANC
                     MVGQELVLKRAKEEARQIALQNLEKVGMAQYINARPSQLSGGQQQRVAIARAISMDPEI
                     LLFDEPTSALDPEMVGEVLSVMQNLANTGLTMIIVTHEMAFARDISDQIFFISDGIIAE
                     QGKPDQLFNHPQNEKTTKFLSNFQNN"
     gene            complement(7695..8609)
                     /locus_tag="DS833_RS00325"
                     /old_locus_tag="DS833_00325"
                     /pseudo=""
     CDS             complement(7695..8609)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020089477.1"
                     /locus_tag="DS833_RS00325"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DS833_00325"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MANNAANAPLANRVRPKNLDEFVGQ"
     misc_feature    9444..9458
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 23.04"
                     /tool="antismash"
     gene            <9749..9912
                     /locus_tag="DS833_RS08135"
                     /pseudo=""
     CDS             <9749..9912
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558254.1"
                     /locus_tag="DS833_RS08135"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="ETIFNLMKREKISSIAEMYAVL"
     gene            complement(10001..11317)
                     /locus_tag="DS833_RS00335"
                     /old_locus_tag="DS833_00335"
     CDS             complement(10001..11317)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="DS833_RS00335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00335"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_118895789.1"
                     /sec_met_domain="LANC_like (E-value: 3.7e-50, bitscore:
                     163.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNQNDKIIFEISKKILNPNIHKYFQKRYCSSIYKNFNWNPISLA
                     TGEPGLIILANEIEKHGILKNDETFIDTHIELLLKSLKNEKVHSISLFDGVVGVAFSLL
                     LLERIDLEPVIKQINDLIYYKLDFIFSAQNIKKRTSNYDYDLMYGLSGVMNYLLYYYSK
                     SYGNEKTKAKKYIKKICDLFVTLYLNTTANVKGKKVPNWFISSEDQMSQEDSIKYPNGN
                     FNVSMSHGISGIISVLSEAVMLGIGGISCKKLLKNMIDFILKSLVLVNGIYTCPLFISF
                     ESYIYDLPENINLRFDSWCYGAPGIMMALMYAGRALDKSDLYKFSKNNLAKILLSENIE
                     GIDSPSFCHGYAGLLAILLGNFKFTDKNINFFNKSIFNYYDKNNPIGFLDLKYTDNQTS
                     ALFPDLGILSGVSGILLSMIWANKGAKTDWMKIYNLNLF"
     gene            complement(11310..13061)
                     /locus_tag="DS833_RS00340"
                     /old_locus_tag="DS833_00340"
     CDS             complement(11310..13061)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="DS833_RS00340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00340"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_118895790.1"
                     /transl_table=11
                     /translation="MNQIRKTFKLISNQQKLLLMSLIIINIFIGLLPIFSVYLVQNIIN
                     ILTTGKKIHILLILFAIYILLSIIENFLSSLQNYINGKISNYLSFSLEKKVLDAIDNID
                     LKDFENEETYSEIDKVSNEAPEKPFEVFNSLNNIFISLITMISGIVYLFKINIYYSLSL
                     FLLTLISIPILLSLSNRQFLIHWKRAEKERKAWYIKYIMTHDFGVKEIKFFNVGKYLKE
                     KFIKLKKEFINQDLKLLKSLSIFNFLYEFFVVLITGGIVLSVAESIYFGRALIGTLTSV
                     TQIISLTRENTSSIINELYDLKYDLSLLERLFVFLEKNNPNNFVVIENEKKELKRVNEI
                     RAINLKYGNNKNRLILKNINFSIKKGMLVAIVGKNGSGKTTLVKLLSGLYEPYEKKSLL
                     INNVDITDYKKGSLHKKISVLFQDFVKYEFTLQENIGIGDIDEINNTEKMKEILTKYAK
                     SLNKNIQLSQQLGTWFSSSQQISGGQWQGVATSRAMFNQKSDVVILDEPNSALDPIAEQ
                     KLFLQFREFVTKDKIGIFVSHKIAAVKNSDLILVLNNGSIVACGTHKQLMKSSKEYREL
                     EKAEKYE"
     gene            complement(13099..13848)
                     /locus_tag="DS833_RS00345"
                     /old_locus_tag="DS833_00345"
     CDS             complement(13099..13848)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.5"
                     /locus_tag="DS833_RS00345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00345"
                     /product="ABC transporter permease"
                     /protein_id="WP_118895791.1"
                     /transl_table=11
                     /translation="MMINIIKANFLKNRHSKVIITSCTLSSMYSILSVLIFLSYENQSS
                     RQIFKIYNWFFLGLVILSQFALSIFIPFLFTPDKEAGNYAYDLRLGVPREKIFVSKYIY
                     VSIILLIVELISVVLFTFFEFLLGFDQVPILQIILLSFLVFIFLSFPICIYLIVNYKYS
                     YNGTLLIGVIFSLSGILLGTTALGTNIWHFFPWTWGIVACEKLKFGLFNRFEILKFYRI
                     GVICIFLILIMLLLSTYWFKKAEIKTN"
     gene            complement(13838..14593)
                     /locus_tag="DS833_RS00350"
                     /old_locus_tag="DS833_00350"
     CDS             complement(13838..14593)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024141.5"
                     /locus_tag="DS833_RS00350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00350"
                     /product="ABC transporter permease"
                     /protein_id="WP_118895792.1"
                     /transl_table=11
                     /translation="MLKKVIATEFLKDKRSSNRKMIVILPFIFTILSFLLTLLMGQNPE
                     GRSNLVAAAYNWLPLIILPAMVTLLSTNILDEEKENNKIFYKTKNINTYHVLFAKNLVV
                     FVQLLIMLLLFSFLIFLAGKFLGDNVSIFSLLEGSIGLVIGFLPIIIISFILKLHFKTL
                     IVILGNFILGIIGAVAALSQWWFVFPWCYGLKLMAPILLINPNGTFLSQNSELANNFNI
                     FMVSIMAFLVYILLLVLQIKLLKRSDNDD"
     gene            complement(14606..15274)
                     /locus_tag="DS833_RS00355"
                     /old_locus_tag="DS833_00355"
     CDS             complement(14606..15274)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002960078.1"
                     /locus_tag="DS833_RS00355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00355"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_118895793.1"
                     /transl_table=11
                     /translation="MDLILQTSKLSKNILKDVSINVSRNSVYGLLGPNGAGKSTFLKLI
                     TGVWRPTNGEIFFNNQHWKHSDLKRIGALIDGPAIYPNLTAYENLKVVSTILNIKEERI
                     EKTLELIDLKKENKCVKKFSTGMKQRLGIGMAIINKPDLLILDEPTNGLDPLGIENLRK
                     FIISLRDNGVTVIITSHILSEVQQIADTVGIISNGRLVYEEKNDKDKDLEKIFVKAVNQ
                     "
     gene            complement(15317..18304)
                     /locus_tag="DS833_RS00360"
                     /old_locus_tag="DS833_00360"
     CDS             complement(15317..18304)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="DS833_RS00360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00360"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_118895794.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 8.3e-82, bitscore:
                     268.1, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 3.5e-08,
                     bitscore: 27.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.5e-15, bitscore:
                     49.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKENRFKVLDTMYYRRHVLDKKIELKELYTEKILNTASKNKIFM
                     EQLEVTSPNLFQELKKYNQGVETTSAKKKKHLIESISKYYLRATYRNTPLGIFSSVGVR
                     NMANSCSTSQQYKKKIVIGYDWIYDIWHKLINNHFDKFQYTFNNHLTEVDGSLFFLSGP
                     ENTKQNLGFKIKRSPVIDLITKVCYKKYANFNEIKQILKNSYPEVSDSFLDAYIKKLID
                     NNIIIPTFFLSLGKKQNEVLTQLVKITNNVGENQYVSSLKQIIHLIKKYEQSKVGNSSY
                     FSKIKEKMNDIAPVKENSLNVDLYSDWNIVQLSQQDLDNIIKVIEFLTDISSPINILDT
                     YIDSFIEKFGADAEVPLSVVIDPNIGIGLPKEESNEKSHIQNSTLLGVQNFFAEKIELA
                     LIKHKDIELTDTDFDQVRKFLNTDINEEQQGKIPKSFEVCFNTMINKNQVNNFYISEIL
                     GSTELFSLEGRFDDLLINAPKYKTRDIESCDINTIPSKYDYMNIYHNKHEGDSELSIGL
                     ITQNNKNDVQLNDLSIGYANEQLYIRNRKNNKIIMFNDRNMFNDNLKNPIIKFLLELNN
                     QNTKWWFNMPWLSSFSNYCYIPAIKYKNITISPSTWIFTVPKYRKNHNTDFVNFKSEFL
                     EFAKKFQLPNYFYYVEMDNKIICDLSTESLYVMFKETRKGNSKYILLKEIEKNLLKNPE
                     NNEDIVLEFCSNNYGLSNNKIPVLPVYDPVSTVPVNNKINGYLYFEIIFGNQRMVKNFL
                     RSQLSEFLNRNNKLYQRYFYIQYETLDYNRQPSIRLRFYENKDENINRLENNAISWLSS
                     LLHKSCISSFKIKNYVPEVYRYGGVTNLGLAEEIFEKDSNIALFILKNIESENQKFYIL
                     YSLITLILEGTINIDNAISFMKNNYVFDTKSFKEEKIWFRENAKSLGHLGEDLNKDFKK
                     MIKSRGRSVKSLINKDEYKRPENMLLSLLHMNCNRILGVSRNDENDIMYLTFKTLELFK
                     HTDKIL"
     aSDomain        complement(17624..17872)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DS833_RS00360_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="8.10E-09"
                     /identifier="RREFam001.1"
                     /label="DS833_RS00360"
                     /locus_tag="DS833_RS00360"
                     /protein_end="227"
                     /protein_start="144"
                     /score="27.1"
                     /tool="antismash"
                     /translation="TFNNHLTEVDGSLFFLSGPENTKQNLGFKIKRSPVIDLITKVCYK
                     KYANFNEIKQILKNSYPEVSDSFLDAYIKKLIDNNIII"
     gene            complement(18526..18726)
                     /locus_tag="DS833_RS00365"
                     /old_locus_tag="DS833_00365"
     CDS             complement(18526..18726)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_a"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249978.1"
                     /locus_tag="DS833_RS00365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00365"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_118895795.1"
                     /sec_met_domain="TIGR03731 (E-value: 3.3e-18, bitscore:
                     58.4, seeds: 23, tool: rule-based-clusters)"
                     /sec_met_domain="mature_a (E-value: 3.8e-07, bitscore:
                     22.3, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNFSDFDLQLNDVTSGSKRGLEPRITSKSLCTPGCITGRLMGCN
                     SKASYKCSINIGSGGKGHHKK"
     CDS_motif       complement(18652..18726)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MTNFSDFDLQLNDVTSGSKRGLEPR"
                     /locus_tag="DS833_RS00365_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18526..18651)
                     /prepeptide="core"
                     /locus_tag="DS833_RS00365_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="10.50"
                     /molecular_weight="4062.8"
                     /monoisotopic_mass="4060.1"
                     /core_sequence="ITSKSLCTPGCITGRLMGCNSKASYKCSINIGSGGKGHHKK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MTNFSDFDLQLNDVTSGSKRGLEPR"
                     /leader_location="[18651:18726](-)"
                     /alternative_weights="4080.8"
                     /alternative_weights="4098.8"
                     /alternative_weights="4116.8"
                     /alternative_weights="4134.8"
                     /alternative_weights="4152.9"
     misc_feature    18720..18736
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: medium, score: 26.46"
                     /tool="antismash"
     misc_feature    complement(18777..18790)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.56"
                     /tool="antismash"
     gene            complement(19288..20313)
                     /locus_tag="DS833_RS00370"
                     /old_locus_tag="DS833_00370"
                     /pseudo=""
     CDS             complement(19288..20313)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003628928.1"
                     /locus_tag="DS833_RS00370"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DS833_00370"
                     /product="IS30 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNIRQKDKHLNFENLVTIQFLHKQGKSCTRLLRN"
     misc_feature    20495..20508
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.52"
                     /tool="antismash"
     misc_feature    complement(20496..20509)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 26.06"
                     /tool="antismash"
     gene            complement(20761..21936)
                     /locus_tag="DS833_RS00375"
                     /old_locus_tag="DS833_00375"
     CDS             complement(20761..21936)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014074185.1"
                     /locus_tag="DS833_RS00375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00375"
                     /product="AIPR family protein"
                     /protein_id="WP_118895796.1"
                     /transl_table=11
                     /translation="MIRTFKVQSVRTIKSPSNPDIITYFTWVNFKDLPDDFSLEVNPRK
                     PKMTTSVAKQLIKAVRGSNSDFDINNRGMVITAKKVTFETSKSMLTVDLDDDKHRYGVL
                     DGGHTYEAILQNRDEAPSNINKYVKLEIIVGKDLDVSALADARNTSVQVSDIALFELDN
                     KFDFIKQAISSEKKYASEIAYKDNDNKRIPVANLLRLMFAYNLKRYPDDTQVPISAYSG
                     IANVFKDYKKEYGNKSNIYKQLAKQLPKLVQLYEIIQKELPTKYEEFKREEGKRSKFGA
                     VRGISKNGHPKTDFNQDSIKYDISSGYLIPIFGAFRSLLKWNDNKEVYWQFDPIEVWEK
                     IGTSLVQNTFETDTNPQQIGKSKIVWQSNYRIVDGARKDLLIDKLTQETIV"
     misc_feature    complement(21986..21999)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 24.45"
                     /tool="antismash"
     gene            22084..22359
                     /locus_tag="DS833_RS00380"
                     /old_locus_tag="DS833_00380"
     CDS             22084..22359
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013540.5"
                     /locus_tag="DS833_RS00380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00380"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_118895797.1"
                     /transl_table=11
                     /translation="MTLKAKNNCTEEIGKIIKKYRLSLNLKNSSRESFINYSIDAGLVP
                     EGWISTKSLGNIERGQNTPSLHTLKLLATALDINFIDLINEIKDFV"
     gene            complement(22589..22744)
                     /locus_tag="DS833_RS08030"
     CDS             complement(22589..22744)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DS833_RS08030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_182431341.1"
                     /transl_table=11
                     /translation="MLKYVVLLSLTCILLTNLAPALRELGLALDKLANLLDKLKDLLEA
                     ILKIFK"
     misc_feature    complement(22969..22984)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.13"
                     /tool="antismash"
     gene            complement(23180..23683)
                     /locus_tag="DS833_RS00385"
                     /old_locus_tag="DS833_00385"
     CDS             complement(23180..23683)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025105.5"
                     /locus_tag="DS833_RS00385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DS833_00385"
                     /product="thioredoxin family protein"
                     /protein_id="WP_118895798.1"
                     /transl_table=11
                     /translation="MKRAFINIVILIQLCLSVLNCNFQNTKATEIDDTENAGYRDNSEL
                     VLRYQNTEYQKATKTFIKISPKKINKLLDKKNKRIIYVFWGKASCPYCRAFVPGLAKLS
                     KKRKIKIYYINTESTDKDKYLKKERKKYKVESVPTLIKIKNKRHFKVFDRGKSTLNQFL
                     TKNY"
     gene            23820..24347
                     /locus_tag="DS833_RS00390"
                     /old_locus_tag="DS833_00390"
     CDS             23820..24347
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DS833_RS00390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DS833_00390"
                     /product="hypothetical protein"
                     /protein_id="WP_118895799.1"
                     /transl_table=11
                     /translation="MKHLITLLSSAAVCVSMLAVPATTVSAATTTHAQSTATSNQLSKA
                     ETETLNAAIKGSLITYSDSSGVAQVKIVDKDYLAQSLKQTNLKVTVEDVQSALDKVNEY
                     AKNHPDEFTYENPLLRKVKHHKACSWTMAGAGTATSLGWAIGSVVAGATGIGAALIGVG
                     LGAIWTGAGLAC"
     misc_feature    24363..24374
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.48"
                     /tool="antismash"
     misc_feature    25451..25466
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.35"
                     /tool="antismash"
     misc_feature    25510..25519
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.42"
                     /tool="antismash"
     misc_feature    complement(25645..25660)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.38"
                     /tool="antismash"
     repeat_region   25795..27902
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=79066..79093
                     /rpt_unit_seq="ggatcacccccacacacgtggggaacac"
     misc_feature    complement(25976..25990)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 19.94"
                     /tool="antismash"
     misc_feature    26706..26724
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.12"
                     /tool="antismash"
     misc_feature    complement(27872..27886)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 19.94"
                     /tool="antismash"
ORIGIN
        1 ttatttatcg cgctacacaa tggtacgcta acgaactaac tcgcttcggt attaaagtat
       61 atatctacaa taaaggcttt atccacgcta aaacaattgt agtcgacgat gactttgcta
      121 ctgttggttc aatgaaccaa gattatcgtt cttatgacct caactttgaa gacgttgctg
      181 ttttttatga caaaaatttt gcccatgaaa tagctcaatc atttatagcg gacatggagc
      241 attctaccct acttacgcca caaataattg ctaagcaggg gcgcttactg cgaacactac
      301 agtatttttc acgaatgctt tcaccaattt tatagatatc ctgaaatatt aatcacatta
      361 aatgttctta aattatatct tgtatttcaa ttctaatatc atggttgaca tgactcttaa
      421 ttgtacccac tattttcgct atgctctggg caaaacgtaa ataatattga cgattttgat
      481 ttgtagtaag aatacaaatc acttgttttt tcttgggatt aggtacccta attagggtaa
      541 tcaaatcaat atcagcatat gaaattgttc gtttaaaata acccgctact acaactttct
      601 tcgcgccaaa gccagtaaag ccatcaatga tacctatcaa gataaaactg gccaaaaaaa
      661 cagtcagacc ctgatcattt ttttcaatta attgccaaga aaagccaagc caaataaaaa
      721 ttagcgacca gataattgaa gagaatcgat attgtccctt taaatcaata tttgcttgcc
      781 aataccagct ataacaagca tagcccagca taatcgcttc taaaattaag taaaaaccag
      841 ccataaaaac tctcctcaaa atatttactc ttcgtctatt ataacagact acgatttttt
      901 agtagtttta gcagacaatt ttgaactatt ggcttgcatt ttatttaaaa atattattaa
      961 atagtcatta aattaaatgc gatgaaaaag aagagtaaat aatttatttc tcacagtgag
     1021 ttggtattag tgcaaagcca gcagaccctg aattattgaa aaaccctttt agcagcacac
     1081 tgaacaactc aagtaggtgg tgccgtctcc agtacgttat caagctggtg aagcatgatt
     1141 gtgcttcatg agtggttcgc aaatagcgga caatttaggt ggtaccgcgg aaaaagcctt
     1201 tcgtccttgt ttttattagc tgaggcagag ggctttttct ttgacctcaa atcaggaggt
     1261 taacaattat gactttaatt attccccaaa attatcagcc tactttaaca attcgtgata
     1321 ctgaggcggc aattgttttt atccgtgaac gttttcaagt tttactaggg caaaaactta
     1381 atttacagag aatgtccgca cctttgtttg ttgaaaaaaa taccggactc aatgataact
     1441 taaatggaat tgaacgtccg gttgattttg acgtaaaagc ttttcctaaa gacgatacca
     1501 ttgaaatcgt ccattcttta gctaaatgga aacgactggc ccttaaaaaa tatcattttg
     1561 gtatgcatga aggcctctat acaaacatga acgccattcg gcgcgacgaa gaccttgata
     1621 actttcattc gatctacgtt gatcaatggg attgggaaaa aatcattgcc gaagatgaac
     1681 gaacaattac aactttgact gaaacagttg cgcaaatttt tagtgcaatt aagcaagtgg
     1741 aaactgaatg tgctgcacgc tatcctgctt caacttatca tttgccagat gatgtatttt
     1801 ttattactac tcaagaacta gaggatagat ggccagactt gagtccagaa gaacgagaga
     1861 ataagattgc tgagcaaaat aaggccgtct ttcttatgaa aattggtgac aacctggctc
     1921 gtagtagtaa gcctcatgat ggtcgcgccc ctgattatga cgactggcaa ttaaatggtg
     1981 acttgatttt ttggtatgag cccctcaagc aaaaactaga aatttcttca atgggaatta
     2041 gggttagccc gcaaagccta cacaaacagc tcatccaagc taattgcctt gcacgtgagc
     2101 aattaaactt tcatcaaatg ttgctcaacg gcgaactacc atttaccatt ggtggcggaa
     2161 ttggtcaatc acgcctttgt atgcttttat tgggtaaagc tcacattggc gaagtacaag
     2221 ccagtatttg gccaaaggaa atgctagaaa aatgccaagc ccataacatt caaattcttt
     2281 aactatcaac cgacctccaa cttagctaat gctacaggag gtctatttta gtaacacgat
     2341 aattaagcta ttagcataaa ttatctactg cataaatatt gcccagggga aaaattatga
     2401 ttgtaactaa gcaaataaaa actttaaaag ccgaaattga acaagcaaat tatgttacct
     2461 ttttgactgg tgccggtgta tctacaccct ctggcattcc agattatcgc tctaaaaacg
     2521 gtatttataa tgatagcatt gaaaagccag aaactatttt aagtgctgaa acactgtatc
     2581 accgcccaga attgttctat cattttgtct taaataacat gtattttccc gacgctaaac
     2641 caaatattat tcatcaaaaa attgccgaaa tttgtaataa taaaggccat ttagttaccc
     2701 aaaatgtcga tagtctagat ttaaaagctg gcaatcaaca ggtcacccag tttcatggta
     2761 atctctatca gttatattgc acaaaatgcc aacaagctgt taagtattct acctatgctc
     2821 aatcatatct gcaccataac tgtggtggta ttattcgccc ccaaattgtg ttatatggtg
     2881 aaaatatcaa ttctcaaaac ttaactactt ctattcaagc tatccaaaag gctgatctag
     2941 taattatttg cggtactagc tttgtggtct atcctttcgc tcaattatta gcttactgtc
     3001 aaaccaatgc taaaatatgg gcaattaata aaacagcaat tccactagcc gggattgcgg
     3061 ctattactgg cgatgcacta gatgttttca aacaaattta aacagacata tttcttatgg
     3121 taaaatatta ggcaatagct tgattaatgg attattataa gttattgctt aactcaattt
     3181 attattcaaa agctgctagt actttcagaa aagagatttt tacaaatgtc aattattaaa
     3241 atgtatgcgc cattctttaa tgccaataac tggcttcacg ttttaactaa cgtcaatgac
     3301 tggctaatca ttcttaccct aattttgatg gaatgtttat tatcagttga taatgctgtt
     3361 gtacttgcag cccaaaccaa atctttacca gacaaaaagc aacaagaaaa gtctttattt
     3421 tatggtatgt ggggcgctta tatttttcgc tttattgtca ttggaattgg cacgtatcta
     3481 attaattttt gggagattaa attagctggt agtatttatc ttttttacct ttgctccaag
     3541 ttcttctatg atcgacacca ctattcagca gataaagaag gcggtcaagt gccaaaaact
     3601 acccagcgtc atcaaaataa taagcgtttc ctgtcacctt tttggcggac agttatatca
     3661 atcgaggcaa tggatatcgt cttttcaata gattcagttc tagcagccct ggctgtttca
     3721 agtaatcctg tagttgtttt aattggtggg atgattggta ttttatgtat gcgaggtgta
     3781 gctgaagtta ttattaagtt aatggatata attcctgagc tgcaaccaat ggcatatatc
     3841 ttaattggca ttattgcttt aaaattactt gtctcacttc caccacttca ttacgagtta
     3901 ccaaactcta ttttcgccgc tttagtcttt ggcattttgt taattaccat tgcttttcat
     3961 tttttgcact ccaataacca ttctcattaa gcataattta taagttacca ttctttttta
     4021 ggcacaattc aataattgtg tcccttatct tctatgcaac aagtaagctt tataattact
     4081 tacataaatt ataattttac ttaataacta tttgcgagta atcatggact attcaactta
     4141 ttttactaag tcaacaactg aaaaaataag tatcgatttg cttggtcgac ccttaatctt
     4201 tgataatggg caacaaattt taggtggtta tattgtggaa actgaagctt atttaggaaa
     4261 aagagatcgt gctgctcatt cataccaagg tcgcagaact gctgctaatg aaggattata
     4321 tcgcagagga ggcacaattt atatctatgc ccaacgtcaa tatttcttct tcgatattgc
     4381 tacccaaaaa gctggtgaac ctcaaggcat cttaattaga gctatcgaac ctgcttgggg
     4441 tatcaagcaa atgataacta atcgctcagg taaaagtggc cccttattaa ctaatgggcc
     4501 agctaaaatg atgcaagcct tcggtattca taataaagac tggaacttac actttctaag
     4561 caagtctcct tttactattg atttaaatga caaccacaaa aattacgccc gtaagattat
     4621 tgccagtccg cgcattggta ttaaccaatc aagccctgct tgggccagca aacctttgag
     4681 atactacgtt agcggtaatc cttatgtttc tagaatgaaa ataaaagatt atcagccaaa
     4741 caatggctgg aaattattat cttaatataa aaaattgtta tagacatttt aaacacaact
     4801 attgacaaag tcctattttt agcctattat cgcatatata taaagttaaa taatttccaa
     4861 tgcaatagag gttgcgataa ttacaaactt agctggagtg aacgaacact aagaaagcta
     4921 tcgtaagaat tatcgccgaa acaaaaattt tgttcgtttc aattttttgt tgggctgcaa
     4981 gataatatct tgcagactgt cctagttaat tactagggag cgctatatga tttgtctaaa
     5041 taaaattaga ttagacctcg ttgtttttga agtacaacga ggtttttaat tacgcttttt
     5101 attgtattgg ctttatttga gaaaagtttt cggaggtttt caaaatgaag tcaagatata
     5161 aatggattac tgctgttatg atagcaataa tcagcatgac ctttggtttg aattgtaatt
     5221 caaatagcgt caatgctaaa aaagatagta atgtgcttaa agtagcaatg gaagctaact
     5281 atcaacctta taattggacc caaactaatg ctgcaaatgg tgctgtccca attgatggat
     5341 cgcaacatac ttttgctaat ggttatgacg ttaaaattgc caaaattatt ggtaaaaaaa
     5401 tgcatcgaaa agtggttgtg cttaaaaccg aatgggatgg actgctacca gctttaacca
     5461 gtggtaaggc ggatttaatc attgctggta tgagtccaac tgctgaaagg gctaaagcca
     5521 ttaacttttc tcaaccatat cgccgcggaa catttgttgt tattaccaaa ccaaatagta
     5581 agtttgccca cgctaaaaag ctaactgatt ttaaaggtgc aaagttaact gctcaacaag
     5641 gaacatccca ttacgggtta attaaagaat tacctggtgc caaaagacaa actgcaatgc
     5701 gcgactttgc cgcaatgcgc caaagcctaa tttcaggaac aattgatggg tacttagcag
     5761 aagataccga agcaatttct tttaaattag ttgatccaga tgtcactgct gttgctatta
     5821 gtaagatggc tggtttccat gtctcaaaag aagagtcaga aacagccatt ggtattgcga
     5881 aacctaacaa gtctttgctt aaacaagtca atcaaatatt agctaccatt ccaaccgcta
     5941 caagaaacaa aatgatgact gctgccatta aagaacagcc taaggctgat gacaacaaaa
     6001 aaggtcaatc agaaaactgg tttatttcca tgtggaaaca atatggtagt atgctagtaa
     6061 gtggtattgg tatgaccttg cttcttgcat ctgttggtac aattgcaggt ttctttattg
     6121 gtctagctgt tggtattatt agaactatcc ctaccccaac tacaactgga aaaaaattat
     6181 tacttaaagt tagcaactgg ctattatcag tttatattga agtgttccgc gggacaccaa
     6241 tgatggtgca agctgcggta atctactacg gtattgctca attttggcat cttaatatca
     6301 atcggaccat tgcggcttta attattgttt caattaatac tggcgcctat ttagcagaaa
     6361 ttattcgcgg agggattatt tccacaccaa ctggacagtt tgaagctgcc agtgctttgg
     6421 gcatgaccca taaccaacga atgtggcata ttattttacc gcaagcaatt aaaaattgtt
     6481 taccatcaat tactaatgaa tttatcgtca acattaaaga cacttcagtt ttgagtatca
     6541 tttcggtctc agaattgttc tttgtgggaa caactgttgc tagtcagact ttcaagtttt
     6601 tcccaactta cctcacaatt tctgctattt acctgatttt gactttcact attactagaa
     6661 tcttcaattt aattgagaaa catttacaag gtaataaaaa ttacaattta atggccaatc
     6721 aagtacaagt tggtacaacc aatgacatgg aggttaaaaa ataatgacca caacaagtga
     6781 aacaattttg agtctaaaac atttgcaaaa atcttttggt gaacaccaag ttttgcgtga
     6841 catttctctt gatataaaaa gaggcgaaat tgctactatc atcggccctt ctggcggtgg
     6901 taaatcaact actttacgtt gtattaacct cttagaagaa ccaacgtctg gtgaaattac
     6961 ttttcacggt gaaaatgttc ttgcttctta taaccgcaac atctatcgtg ctaaggtagg
     7021 gatggtattt cagcaatttg acttatttga aaataaaaat gtccttgcta actgcatggt
     7081 tggtcaagaa ttagttctta aacgcgctaa agaagaagca cgtcaaattg ccctgcagaa
     7141 cttggaaaaa gttggtatgg cgcaatatat taatgctcgc ccgagtcaac tttcaggggg
     7201 acaacaacaa cgtgtagcta ttgcccgagc aatatcgatg gatccagaaa tcttgttatt
     7261 tgatgaaccg actagtgcac ttgacccaga aatggtcggt gaagttctaa gtgtaatgca
     7321 aaatttagcc aatacgggat taacaatgat tattgtaacc catgagatgg catttgcgcg
     7381 ggacatatct gatcagattt tctttattag tgacggtatt attgccgagc aaggcaagcc
     7441 agatcaatta tttaatcatc cacaaaatga aaaaaccacg aagtttttaa gtaacttcca
     7501 gaataattaa atcagtgacc aaaaaatcat gttttagcaa aaaaacatga tttttttatt
     7561 cagtttacaa ccttgggcct ttgaattcga caactaaatt ttcctttgta gcaaacagat
     7621 tgactgccca aagcaaatat atgattttta taactctttg tgagcatagt ttgcgccaaa
     7681 ttttaaagct cttattaaga atgccgctta tgccattctt taatttgttc aagtcgcctc
     7741 ttgaagcgct tcctcatgac tctgaattgt aggtaacata atattctaaa ctaagcagtc
     7801 tagttttcat tgccgttaac ttcgccttag tttgatgagc atattggtaa ccttgaccat
     7861 aatttaaatc ttgcattaac ttagttgatg cattgcgaat ctgcagaggc acagattcat
     7921 caattgtctt tttaacgtct tagctagacg ggcttcatcg actgcatata attttggtgc
     7981 taaagataaa ataaattaca gtctcaacaa ggtgaacgtc acattctggc atctctaaga
     8041 attgacaagc ttaaaaaaca ttgactgcta catgtaacat atttgtagct gccaatccaa
     8101 tatcttcact ggcaaactta gcaattgaac tagtttcctg ctcatccaac tttcaacttg
     8161 ccaaaaccat ttaggttatt gatagctctc ttaagtaaat taataatgtc tttgacttca
     8221 agcggtttaa gacaaaaaac ttgcatcgcg caagcatgct gaattgacct caaaagaatg
     8281 actttcagta gttgcaccaa actaccgcgt tcaacataag gcaaaaaggc atcctgctgg
     8341 gctttgttga aagaatgaat ctcagcaata aagaccaacg ttttttgacc aagttgtctc
     8401 ttttctttag cctctttcat aattttacga attttactaa tactgctatc aacggtgctg
     8461 aaactataga aactggatta actttgtcgc gcaataattt cccgtagaat tttccccaag
     8521 ccaagtagtt gttattggcc cacaaattca tccaagtttt ttggtcgtac acggttggct
     8581 aacggagcat ttgctgcatt atttgctatt aatgattgtt gttttcatgc taatatcttc
     8641 ttttttaatt tattccacct tgctcttatt atacaagtac ttatcacatt tactaaataa
     8701 atattactga tcaattttta acttaagtaa ttcaagctta tcaataatta ctgcaactta
     8761 agaaataacc tttgcgctag cagtactttc aacataatta ttttcactag tacacataaa
     8821 atggctaatt gatctttgta tcaatgaagc ttgcaaatta ttcagcaaaa taaacaattg
     8881 ctagctgaaa attcttaatt aaacacaaaa tcaagactaa caaaagcaag caaagcaaat
     8941 ttagcaagaa aatacccact aagagcacga atcactcaac aaaaacggga atgttatcga
     9001 taaaccacca agagattgcc cgtttgcatg atatacttga tcttacccaa aagttactgg
     9061 atcaatagca acaattatag ttaatggtta aaaaaattgt aaacctaaaa aatcacaaat
     9121 gacaagaaat ttatagcata atttatgaca atataaaaaa gcgattgata agttccaatc
     9181 actttttgta ttatcacaaa aatacttagt cgttaacttt atttttttaa tatcaatcat
     9241 caaataagct atgcctataa gtagaagtat gatactaggt atatttaacg tactcatatt
     9301 cttaaatata acagcacaga taaacactag ccccaaaatt attaagctcc tatattttgt
     9361 tagtattttt atattgtttc ctaattaaaa cttccgtcaa aatcactaat ggtaatattg
     9421 caaaacacat aattatttac tccttctaaa tttgataact aaactgtcta aataatcttc
     9481 ccaactattc aaataatctt atcctgctaa atattaccac ttttttctac tgaaagataa
     9541 tgataattag taagtggcgt aataaagctt ccatttttgt aacctcccaa ttaaatttag
     9601 ttacctttat ttatacattt aatatattag ataaaataag ccaaaattaa aagcagcacg
     9661 ctgatattgc caggctagat atttctacca tgctaaattt agcatgtcct ttgattgtct
     9721 taagttggga ctacaaacaa tggtgtaaga aacaatcttc aatctgatga agcgggagaa
     9781 gatcagttca atagcagaaa tgtatgccgt actgtagatt acgtttacta gctcaaacac
     9841 atcagaaaat caaacaaact aaaatacacg attccgatca agtatcgaaa tcgtgtattg
     9901 agctgtaatt aacattttaa atgtctaact ttttagttgg acttcactat caggactttt
     9961 tgtattttag aatcattcga ttgcatttaa ttattattta ttaaaataag ttcaagttat
    10021 aaattttcat ccaatcagtt tttgctcctt tatttgccca aatcatagat aataatatac
    10081 ctgaaacccc agaaagtatc cctaagtctg gaaatagagc acttgtctga ttatccgtat
    10141 atttcaagtc tagaaatcca attggattat ttttatcata ataattaaaa atactcttat
    10201 taaaaaaatt tatattttta tctgtaaatt taaagtttcc aagtaaaata gctaataatc
    10261 cagcatagcc atggcaaaaa gatggggagt caattccttc aatattttcg cttaataaaa
    10321 ttttagctaa attattttta gagaatttat aaagatcact tttatctaaa gctcttccag
    10381 catacattaa ggccatcatt attccaggtg cgccataaca ccaactatca aaacgtaaat
    10441 ttatgttttc aggcaaatca taaatataac tctcaaaact aataaaaaga ggacaagtat
    10501 atattccatt taccaataca agagatttta atataaaatc aatcatattt ttcagtaatt
    10561 ttttgcatga tattcccccg ataccaagca taacagcttc agataaaaca gaaattatcc
    10621 cactgatccc atgagacatc gaaacattaa aatttccatt aggatatttt attgaatctt
    10681 cttgtgacat ttgatcttca gatgaaataa accaattagg aaccttttta cctttaacgt
    10741 ttgcagtagt atttagatat aacgttacga ataaatcaca aattttttta atatattttt
    10801 ttgcttttgt tttttcattt ccataactct tagaataata atatagtaag taattcatta
    10861 ctccagacaa tccatacata agatcatagt cataattaga agttcttttc tttatatttt
    10921 gtgcactaaa gataaagtct aacttataat aaatcaaatc attaatctgt tttataacag
    10981 gttctaaatc aattctttcc agtaatagta aggaaaaagc tactcctaca actccatcaa
    11041 aaagagaaat actatgtact ttttcattct ttaagctttt taaaagtagc tctatatgag
    11101 tatcaataaa tgtttcatca ttttttaaaa ttccgtgctt ttctatttca ttcgcaagaa
    11161 ttattaaccc tggctcacct gtagctaatg agataggatt ccaattgaaa tttttatata
    11221 tacttgaaca atatcttttt tgaaaatatt tatgaatgtt tggatttaaa atcttttttg
    11281 aaatttcaaa gattatttta tcattttggt tattcatatt tttctgcttt ctctagttct
    11341 ctgtattctt tactagattt catcaattgt ttatgtgtac cacatgcaac tatacttcca
    11401 ttattcagta ctagaatcaa atctgaattc tttactgcag caattttatg tgatacaaat
    11461 attcctattt tatctttagt tacaaattct ctaaattgca agaataattt ttgttcagct
    11521 attggatcta atgcagagtt aggctcatct aaaattacaa catcactttt ttgattaaac
    11581 attgcacgac ttgttgccac accttgccac tgtcctccag aaatctgttg acttgaacta
    11641 aaccatgtac ctaattgttg tgaaagttga atatttttat tcaaagattt tgcatatttt
    11701 gtcaatattt ccttcatttt ttcagtatta tttatttcat caatatcacc aattccaata
    11761 ttttcttgta gtgtaaattc atatttgaca aaatcttgaa ataaaacaga gattttttta
    11821 tgcagcgatc ctttcttata atcagtaata tcgacattgt ttataagaag agattttttt
    11881 tcataaggct catataatcc tgataaaagt ttaacaagag tggttttacc agatccattt
    11941 ttaccaacta ttgcaacaag cattcctttt tttatcgaaa aattaatatt ttttaatatt
    12001 aatctatttt tattattacc atatttaagg ttaatagccc taatttcatt aacccttttt
    12061 aattcctttt tttcattttc tattactaca aaattattag gattattctt ttctaaaaaa
    12121 acaaaaagtc tttctaataa agacaaatca tactttaaat cgtataattc atttataata
    12181 gagcttgtgt tttctcttgt taaacttata atttgagtaa cactagttag agtaccaatt
    12241 aaagctcttc caaagtaaat tgattcagcc accgaaagaa caatcccacc agtaattaaa
    12301 acaacaaaaa attcatatag aaaattgaat attgacaggc tttttagcaa ttttaaatcc
    12361 tgattaataa attctttttt taattttata aatttttctt ttaggtactt gccaacattg
    12421 aaaaatttta tttctttaac tccaaaatcg tgagtcatta tatattttat ataccaagcc
    12481 tttctttcct tttcagccct tttccaatgt attaaaaact gacgattact taaagataac
    12541 aaaattggta tagatatcaa agtaagcaaa aataaagata atgaataata tatattaatt
    12601 ttaaataagt atacaattcc actaatcatt gtaattaaac ttataaaaat attatttaaa
    12661 gaattaaaga cttcaaaagg tttttcagga gcctcattac ttactttatc tatttctgaa
    12721 tacgtttctt cattctcaaa atcttttaaa tcaatattat ctattgcatc taaaactttt
    12781 ttttcaagac tgaaggacaa ataattacta atcttaccat taatataatt ttgtaaggaa
    12841 cttaaaaaat tctctataat agacagtaaa atatatatag caaacaatat aagtaatata
    12901 tgtatttttt tacctgttgt taaaatattt attatatttt gaaccaaata tacagaaaat
    12961 atcggaagta agccaataaa tatatttatt attatcaaac tcattaataa caatttctgt
    13021 tgatttgata tcaatttaaa tgtttttctt atttgattca ttttatgttc ctcttaagca
    13081 ctataatatt taaaaatttt aattggtttt gatttcagct tttttaaacc aatatgtgct
    13141 gagtaataac atgattaata ttaggaaaat acatattaca cctattctat aaaacttaag
    13201 aatttcaaat cgattaaata agccaaactt taacttttca caagcaacaa taccccatgt
    13261 ccatgggaaa aagtgccaaa tatttgtccc aagtgctgta gttcctaata atatgccgga
    13321 aagactaaat ataactccta ttaaaagagt tccgttgtag ctatatttat aatttacaat
    13381 aagataaata catattggaa agctcagaaa tataaatact aaaaatgata acaaaataat
    13441 ttgcaaaata ggaacctgat caaaaccaag caaaaactcg aaaaacgtaa acaagacaac
    13501 cgaaatgagt tcaacgatta ataatataat tgatacataa atgtatttac ttacaaaaat
    13561 tttctctcta ggaactccta atcgtagatc ataggcataa ttacctgcct ctttgtctgg
    13621 agtaaaaaga aaggggataa aaatacttaa agcgaattga ctaagaataa ctagacctaa
    13681 gaaaaaccaa ttatatattt taaatatctg tcttgaagat tggttttcat agctcaaaaa
    13741 aatcaaaacc gaaagtatag aatacatact ggataaagta caagaagtga taataacttt
    13801 tgaatgtcta tttttcaaaa aattagcttt tattatatta atcatcatta tcacttcttt
    13861 taagtaattt aatttgcaat actaataaaa gaatataaac caagaatgcc ataatagaca
    13921 ccataaaaat attaaagtta ttggctaatt cactattctg ggaaagaaaa gtaccgttag
    13981 gatttattag caaaattggt gccattaatt tcaatccata acaccatggg aaaacaaacc
    14041 accattggga taaagctgca acggcgccta ttatacctaa aataaagtta cctaaaataa
    14101 ctattaaagt tttgaaatgc aatttcaata taaatgaaat aattattatt ggtaaaaaac
    14161 caataactaa acctattgaa ccttccaata aactaaaaat tgaaacgtta tctcccaaaa
    14221 attttccagc taaaaatata agaaaactaa aaagaagcaa cataattaat agttgaacaa
    14281 aaacaactaa atttttggca aataatacat gatatgtatt aatatttttt gtcttataaa
    14341 atattttatt attttctttt tcttcatcta aaatattagt cgagagcaat gtcaccattg
    14401 cgggtaatat aattaaggga agccaattat aagctgcagc tactaaatta cttctccctt
    14461 ctggattttg acccataagt aaggtaagta aaaaacttag aattgtaaaa ataaacggta
    14521 aaataactat catttttcga ttacttgagc gtttgtcctt taaaaactcc gttgcaataa
    14581 ctttttttaa catttgaatc ggctcctatt gattaacagc tttcacaaaa atcttttcca
    14641 aatctttgtc tttgtcattt ttttcctcat atactagacg tccatttgat atgataccaa
    14701 ctgtatcggc tatttgttgc acttcgctta aaatatgact tgttataatt actgtcaccc
    14761 cattatcccg tagggaaata ataaactttc gtaaattttc aattcctaaa ggatctagtc
    14821 catttgttgg ttcatctaga atcaacaaat caggcttatt tattattgcc atacctattc
    14881 ctaagcgttg tttcatacct gttgaaaatt ttttgacgca tttattttct tttttaagat
    14941 caatcaactc taacgtcttc tcaatacgtt cttctttaat attaagtatt gtagaaacca
    15001 ccttcaaatt ttcgtaggct gttaagttag gataaatagc gggaccatca attaacgctc
    15061 caatcctttt taaatcagaa tgcttccaat gctgattgtt aaagaaaatt tccccattag
    15121 taggtcgcca aactccagtt ataagtttca aaaaagttga ttttccagca ccatttggtc
    15181 ctaaaagacc atataccgaa tttcttgaca cattaattga gacgtctttt aaaatatttt
    15241 tacttaattt actagtttgt aaaatcaaat ccatgttatc cctctttcat ttctaataaa
    15301 cacatagttc acatatttaa agaattttat ccgtatgttt aaacaattct aaagtcttga
    15361 atgtcaaata cataatgtca ttttcatcgt ttctgctaac acctaaaata cggttacaat
    15421 tcatatgcaa caagctaagc aacatattct caggtctttt atattcatcc ttattgatta
    15481 aagatttaac agatctgcct ctacttttaa tcattttttt aaagtcttta ttcaggtctt
    15541 cgcctaaatg tccaaggctt tttgcatttt cacgaaacca tattttttct tccttaaagc
    15601 ttttagtatc aaaaacatag ttgtttttca taaaagaaat agcattgtca atattaattg
    15661 tgccttccaa tattaaggtt ataaggctat aaagtatata gaatttctga ttttcacttt
    15721 ctatattttt caaaataaaa agagctatat ttgaatcttt ttcaaatatt tcttccgcca
    15781 aacctaaatt tgttactcca ccatatcggt atacttccgg tacataattt ttaattttaa
    15841 aactacttat gcaactctta tgcagtaaag atgagagcca agaaatagca ttattttcaa
    15901 gcctattaat attctcatct ttattttcat aaaacctcaa tcttattgag ggttgcctat
    15961 tgtaatctaa agtttcatat tgaatataaa aataacgctg gtataatttg ttatttctat
    16021 ttaaaaattc agataattgc gatctcagaa aatttttgac cattctttga ttaccaaaaa
    16081 ttatttcaaa gtatagatat ccattgattt tattatttac aggcactgta ctaacaggat
    16141 catatacagg taaaactggt attttgttgt tacttaatcc ataattattg ctacaaaatt
    16201 ctaagactat gtcttcatta ttttctggat tttttaatag atttttttct atttctttca
    16261 acaaaatata cttactattt ccttttcttg tttctttaaa cattacatat agagactctg
    16321 tgcttaaatc acatattatc ttattatcca tttctacata ataaaaatag tttggtaatt
    16381 gaaatttttt tgcaaattct aaaaactcac tcttgaaatt tacaaaatca gtattatgat
    16441 tttttctata tttcggtaca gtgaaaatcc atgttgaagg actaattgtt atatttttat
    16501 acttaatcgc aggaatataa cagtaatttg aaaaactact tagccatggc atattaaacc
    16561 accacttagt gttttgattg ttaagttcca ataaaaattt tataattgga tttttcaagt
    16621 tgtcgttaaa catattacgg tcattaaaca ttattatttt attatttttt ctatttcgaa
    16681 tataaagttg ttcattcgcg tatccaatac ttaaatcatt caattgaaca tcatttttat
    16741 tattttgagt tattaaacca atagataatt cactatcgcc ttcatgctta ttatgataaa
    16801 tattcatata atcatattta ctaggaatag tattgatgtc acatgattca atgtctctgg
    16861 tcttgtattt aggtgcatta attaaaagat cgtcaaaccg accttccaaa ctaaataatt
    16921 ctgtagagcc taatatctca gaaatataaa aattatttac ctgattttta ttaatcatag
    16981 tgttaaagca aacttcaaat gatttaggaa ttttaccttg ttgttcttca ttaatatcag
    17041 tatttaaaaa ttttcttact tgatcaaaat cagtgtctgt caactcaata tctttatgct
    17101 taataagtgc aagttcaatt ttttctgcaa aaaagttctg gacacctaat aaagtagaat
    17161 tttgaatatg acttttttcg ttgctctctt cttttggtaa accaatacct atatttggat
    17221 caataacaac acttaagggt acttcagcat ctgcaccaaa tttttctata aatgaatcaa
    17281 tataagtatc caaaatattt ataggagaac taatatctgt taaaaactca ataactttaa
    17341 taatattatc aagatcttgt tgagatagtt gtacaatatt ccaatcagaa tacaagtcaa
    17401 catttaaact attttctttg actggagcta tgtcgttcat tttttctttt attttagaaa
    17461 agtaagaact attgcccact ttagattgct catacttttt tattaaatga ataatttgtt
    17521 ttaaagaaga cacatattgg ttttctccta cattatttgt aattttaact aattgagtaa
    17581 gaacctcgtt ctgttttttt cctagtgaaa gaaagaaagt gggaataatg atattattgt
    17641 ctattaattt ttttatataa gcgtctagaa aagaatcact gacttcagga taactgtttt
    17701 ttaatatctg ttttatctca ttaaaatttg catatttttt atagcaaact tttgttatca
    17761 aatcaatcac tggagatcgc ttaattttaa aacctaaatt ttgcttagta ttttcagggc
    17821 cagataaaaa aaatagacta ccgtcaactt ctgtaagatg attattaaaa gtatattgga
    17881 atttatcaaa atgattattt attaatttat gccatatatc atatatccag tcataaccta
    17941 taactatttt ctttttatat tgttgagaag ttgaacatga attagccata tttcttactc
    18001 caacactcga aaatattcct aaaggtgtat tcctataagt agctcgtaaa taatacttac
    18061 taatagattc aattaaatgc tttttctttt ttgctgaagt ggtttccacc ccctgattat
    18121 attttttcaa ctcctgaaat agattagggc tagttacttc aagctgctcc ataaatattt
    18181 tatttttact agctgtattt aaaatctttt cagtatacaa ttcttttaat tctatttttt
    18241 tatctaatac atgtcttcta tagtacattg tatcaagtac tttaaatcta ttttcttttt
    18301 tcattatatt agtcttttcc tacactattt ttaaaaaatt cgatttatca atttaataaa
    18361 aatataatac attattgcta ttttttattt taaataaaaa aacatatgaa atagtagata
    18421 tttcatatgt tttaatcata actactaaaa tttagttata atattataac gctttttcaa
    18481 aaaataaaat taaaagttaa aaataatcta aatttttatt tctaattact tcttatggtg
    18541 gccttttcct ccagaaccaa tgttaattga acatttatac gatgctttag aattacagcc
    18601 catcaaccga cccgtaatac atccaggtgt acataaagat ttacttgtaa ttcttggttc
    18661 taaacctctt tttgaaccag aagtcacatc atttaactgc aaatcaaaat cactaaaatt
    18721 tgtcataata taatattcct ttctaataaa agcgttatca tgataattat atttgatttt
    18781 ttttaaaaaa gcaagctttt ttagtttaaa tcacttaaaa ttgtttacct tactaaacat
    18841 ataaataaaa attaaataag aaaagcttat cagaaatcaa aaaaatttat ttatatcaat
    18901 ttaacttact agctagtcac tatcattaga ttgttcagct aatacttgtt caaatgccgt
    18961 actaatatca tctgtagttt gtatatttct tgaatttgta tttatattcg agtttaattc
    19021 taccaattgt ttttgtaaat ttttaatttc catcattaat aagtttagca atctcagatt
    19081 tatcactggg atcacatcca ttctgagtat ttatttttgc ctttcttatt ttttgtatat
    19141 tgcgaagaat atgttctagt ttaaatgcct ttttttgtaa ttgagtttca ttattgatac
    19201 gatacaagta tatgtgatct tcttcaacac caagaaagct tgaatagtaa aattcggaaa
    19261 ttgcaatatt aagttgaaca cttttttcta agcagctcga taaattttat ctatttcgtg
    19321 ttcaaataaa tcttctgggg tatgataagc taaaatattt cttggcaagc cattgcacca
    19381 ctcttctatt tctgatgttg taagagtaga gtaattctta attgcttcac cttttaggaa
    19441 tagagcgcct aatcagcttt ttgtgacatt ctacaccgcc ttcatcacaa gaagtatgat
    19501 aatgggcgct agtaactaac gtgcttaaaa gttcttctaa acttgataaa tctgcaaatt
    19561 cagcaccatt gtctgtggta attgttttga aaatgtcgtc cctgtgctca tcatagttat
    19621 ggcataatct tgctaaagca gccatcacac tggcatatcc ttaattttga taatgaagaa
    19681 ttcccgagtc atccgctcat aaaagggcaa aaggacgtta tcatttttag ttttattgcc
    19741 taggaataag tcacattccc cgtgaccaaa ttcaagccga gtttcaatca gcggattgcg
    19801 ttcttcaata ctgcggacta acttcttctt gttctgccta atttgtttac gcttagtatt
    19861 tgctagttaa cttttcagat agatcaagag gcttaatctt aagagagcca cggtcaacgt
    19921 agttttatag cgttttggtg ctaactacct ggttactagt aaatttgcca gtagtagttt
    19981 attcacccca actagcatct aaagaccaat gcttagagct aaagaatcgg tcttcaacct
    20041 accggataaa atcatgttta gctaggaaag cagatttatg gtcaaaatta gaacgcttat
    20101 tttgatatct agtttgagcg gttttagtat cataacgata ttttttgcca tgatagaagg
    20161 gattttgtcc tcttcggagt tcatacataa cagtagaagt cgaacagttt aattccttaa
    20221 caatcgtgtg caagatttac cttgtttgtg caaaaattga atagttacaa ggttttcaaa
    20281 gttaagatgt ttatcttttt ggcgaatatt catgttagaa tgtaaataag tccatggata
    20341 ctcctgatga atattgagtt ggtaattaca ttctaacaga aagagccagg gggctttttt
    20401 ctttaaaaca gcaagattta gtctcgctgt ttaatttgat tatacaatct ctcaaataaa
    20461 tttaaataaa aaatggtgaa ttcgctattt atttattttt ttaaaaaata ttgctaattc
    20521 ttgcccatac tcttgcatac caattaaaga agcgctttcg atctgtagtt aaccctcaca
    20581 aagatactgc cattcacttc aaaattgcca catctaactt aattgcccat tggcaaaaac
    20641 gtttttaatg aaagctgtct tgatgctctc tttaccaaac aaggccaacc accgatgaaa
    20701 acattacgag cacaactgaa actaaaaaag accgccaaaa atgttggtgg tcaaactatt
    20761 ttaaacaatt gtttcctgtg ttaatttgtc aattagcaaa tccttccttg ctccatcgac
    20821 aattctgtaa ttagattgcc atacaatttt actttttcca atttgttgtg gattagtatc
    20881 cgtttcaaaa gtattttgaa ctagactagt tcctattttt tcccaaactt ctattggatc
    20941 aaattgccaa taaacttctt tattatcatt ccattttagt agagatctaa aagcaccaaa
    21001 aataggaatt aaatatcctg aagatatatc atattttata gaatcctggt taaaatcagt
    21061 ttttggatga ccatttttgc taattccacg cacagctcca aattttgatc ttttaccttc
    21121 ctctcgctta aattcttcat atttggttgg taattctttt tgaattattt catatagttg
    21181 tactaattta ggtaactgtt ttgctaactg cttataaata ttagacttat ttccatattc
    21241 ctttttataa tccttaaata catttgcaat accagaataa gcagatattg gaacctgagt
    21301 gtcatcggga tatctcttca aattataagc aaacatcagt cttaataagt ttgctacagg
    21361 gatacgttta ttatcattat ctttataagc aatttcagac gcatattttt tttcagatga
    21421 tatagcttgc tttataaaat caaatttatt atctaattca aataaagcaa tatcacttac
    21481 ttgaacagaa gtatttcttg catccgctaa agctgacaca tctaaatctt ttcctacaat
    21541 aatttctaat ttaacatact tatttatatt agatggtgct tcatctcgat tttggagtat
    21601 tgcttcgtag gtgtgcccac catctagtac cccatatcta tgtttatcat catccaagtc
    21661 aactgtcagc atacttttac ttgtttcaaa agtcaccttt ttagcagtga ttaccatacc
    21721 acgattatta atatcaaaat cactatttga tcctcttaca gcttttataa gttgcttagc
    21781 aacagaagtt gtcattttag gttttctagg attaacttca agcgaaaaat catctggaag
    21841 atctttgaaa tttacccaag taaaataagt aataatatca ggattggatg gtgatttaat
    21901 agttctaaca gactgtactt taaaagttct aatcataaaa ctatctcctt ctaaattatt
    21961 tcagcttaag ctatttgcta aactttaaaa ataattatat aatttatttg tgaaaaaata
    22021 aatgaaccgt ggttccttat tattataaaa ttatgatcac taactgttag tgaaagaaac
    22081 aatatgacac tcaaagcaaa aaataactgt actgaagaaa ttggaaaaat tattaaaaag
    22141 tatagactta gtctaaattt aaaaaatagc agtagggaat cctttatcaa ttacagcata
    22201 gatgcaggtt tagttcctga aggatggata tctaccaaaa gtttaggtaa tatcgaacga
    22261 ggacaaaata ctcctagtct ccatacatta aaattattag ctacagcctt agatataaat
    22321 tttattgatt tgataaacga aataaaagat ttcgtatgaa taactatacc aaaacaactt
    22381 aacataatgt gcattaagca aagtaggtaa aaaagcacta ctaaatctgg aaaaaataat
    22441 tatcctcaaa ataaatttat gaaatttaat ctgtatagca tataaaaagc ccgaatcaac
    22501 ggttttttta tttcggtaat ttttattatt tcacaattag accaatcaaa aaaagcgcaa
    22561 aattttcttg cgcttttccc tcgcaatttt acttaaaaat tttaagtatt gcttcaagta
    22621 aatctttcaa cttatcaagt aagtttgcca atttatctaa agcaagtcca agttctcgca
    22681 aagcaggtgc taaattagta agtaatatgc aagtaagaga taataaaact acgtatttta
    22741 gcattacgca caccttcttt catggaagtt aatcgaactt cccgagattg cgcactaaaa
    22801 aacgtgcatt accattttac catgctataa ttattcataa gagataataa actacgattt
    22861 tagtagtaaa acgtgcgtgc gacttaatca atcgcaagac gtctggggcg gtccgcaagg
    22921 atcgcttttt tgtttctttt ttaaaagaaa atcgtagccc acaaggccac gaccagacga
    22981 taaaaaataa gcattagtcc cgccgacttt tgcttatttt tttcgttgct aatttcaatt
    23041 aaatatccaa caatctaagc tttagcttgt atcaaaaacg gtatcgctta tacggccgta
    23101 taagcaatca tgattttacc taaggctaaa gtcagaaggc tgtatatcta gtcaaaaatg
    23161 gggtaaaaaa gcacatgtat caataatttt ttgtcaaaaa ttgattcaaa gtacttttac
    23221 ctcgatcaaa cactttaaaa tgtcttttgt ttttaatttt tattaatgtt ggaacacttt
    23281 caaccttata cttttttcgt tcttttttta aatacttatc tttatctgtg ctttcagtat
    23341 ttatgtaata aatttttatt ttcctttttt tactaagctt tgctaaccca gggacgaaag
    23401 ctctgcagta tggacaagag gcttttcccc aaaatacata aatgattctt ttgttttttt
    23461 tatcaagtaa tttatttatt tttttaggag aaattttaat aaaagttttg gtagcctttt
    23521 gatactctgt attttgatat cgtaacacta attcactgtt atctctatat ccagcatttt
    23581 cagtatcatc aatttcagtt gccttcgtat tttgaaaatt acaattaagc acagataggc
    23641 ataactgtat caaaataact atattgataa atgccctttt cataattatt gcccctttat
    23701 atatttttat attaatttat attgatttta ttacaaacct atactattat tataatcaga
    23761 aagaagttaa agtttcaaac tttcaaactt ttattttaat tatagaaaga agaataaata
    23821 tgaagcattt aataacctta ctgtcatcag ctgctgtgtg cgtttcgatg ctcgcagtac
    23881 cagctacaac agtatctgca gcaacaacta cccatgctca atcaacagca acgagcaatc
    23941 agctatctaa agcagaaact gaaactctta atgctgctat caaaggatct ctgattactt
    24001 attcagattc atccggcgtt gcccaagtca aaattgtaga taaagattat ctagcacaat
    24061 ctttaaagca aactaatctt aaagtaactg tagaagatgt acaatctgca ttagataaag
    24121 ttaatgaata tgctaaaaat catccagacg aatttactta tgaaaatcca cttttaagaa
    24181 aagttaagca tcataaggct tgttcatgga caatggctgg agcaggtaca gctaccagtc
    24241 tgggatgggc aattggatct gtggttgcag gagctactgg tataggagca gcattaattg
    24301 gtgttggtct aggagctatt tggacaggag caggtcttgc ctgctaatat agtataagca
    24361 atgaaaaagt taactaataa atattattta acgataatgt ttttcctgat aacatcaatc
    24421 actaccctca gtccgatttt cattcgttca aggtctggcg gaatttggag gctatggttt
    24481 attatacttt ctacatttac aatgtttgct aacgaatatt tagctaatca tgctaaagtt
    24541 aacattagta aaagaaagtt gaaagttaca gccggtattg tatcgttaat tattattttg
    24601 gcagtttttt tattctttgg attttggact gattggagtt acctttaaag ttgtctaaaa
    24661 gcatacaaaa aagtactggg attaattctt agtgcttttt tatataatac tttaagttct
    24721 atttttcgaa aattgctact aaaaacagta tgggggaagc taataaaatg aaaaaacaaa
    24781 taacttctat accaaatacg aagcttatca ccatctctac actactcaac attttaccgg
    24841 tttcgcgttt tcggtcttat tttaatcata atctggagct ttaattaatc gcactctttt
    24901 gaattaatag aaaaaagcat tgaacttatg attcaaggct tttcgtgcat cttacttaaa
    24961 caattttaat aactcactta acatattcag aacgtgttct gtcttgttta aaattaaata
    25021 caacatgatg aaaattagaa cgtcttgtac gatttttacc tcctttacag agagactagc
    25081 taaatctctc aggatggcgc gcaaagcgtg cacaatcatt ttaccaaact tatttatccg
    25141 tgttataatt tggtagatga agattacaag ttacggcttg tacgaaaaac agagtgtgca
    25201 tgcaggttag ctactttcaa gacgtctggg gcggtccgca aggatcgctt ttttgtttct
    25261 ttttctaaag aaaatcatgg cccaaaagaa aacgaccgga cgataaaaat aagcattagt
    25321 ccctcctgct tattttttat catgaaattt tgacccttat acaattttgc caaaattgaa
    25381 ttaagcagaa atggtgctag ctttttctgt ttcgccccct gtggcgcatt taagaggtgc
    25441 acagcgggca gtaaccgtta agtcacgccc tctcttgccc taactgaact agcgcataaa
    25501 tacggcattg aacgcgaacc aggcttaacc aatcaattaa aaaacgtcca cgaataccag
    25561 caggctatcg tgacgttgac caaattcaaa ccttaactct gcaacaaaaa aataaaagag
    25621 ttgcattagc agttgaatta agtgatcaaa aaatcgttag ccaagaatta gaccaccaaa
    25681 tctagcacat aatctaaagt tgtagagcat attaggcaac atttttacca acaaaaacct
    25741 gattcaagtc actttgaaca caactaagtt catcaatacg ttttgaccat tgtcgggatt
    25801 actcccacat acgtggggaa cacgaactac gcgatttgca aaatcggcta actcaaggat
    25861 cacccccaca cacgtgggga acacagcaga ctataaagct ctgctaaaag agaaagagaa
    25921 tcacccccac acacgtgggg aacactataa tcgtgctaat caagatgtaa cttatatggg
    25981 atcaccccca cacacgtggg gaacactttc tgctcgccac gcatgacaga tgacaggtag
    26041 gatcaccccc acacacgtgg ggaacactat taagattact tgtttgaagt cccgaggaaa
    26101 ggatcacccc cacacacgtg gggaacacta ttaagattac ttgtttgaag tcccgaggaa
    26161 aggatcaccc ccacacacgt ggggaacact attaagatta cttgtttgaa gtcccgagga
    26221 aaggatcacc cccacacacg tggggaacac tcttttttct gcactatttt taccatgcga
    26281 agcggatcac ccccacacac gtggggaaca ctaggaattg atcctgtgag agtagattat
    26341 aaagaggatc acccccacac acgtggggaa cacaataaca aagtgcttcc agtcgtaata
    26401 agtgcaggat cacccccaca cacgtgggga acactgtaaa tttagtccta gcgcgccctt
    26461 gccataaggg atcaccccca cacacgtggg gaacactttg tatatcacgc tgcaggagct
    26521 atccactcag gatcaccccc acacacgtgg ggaacactca agtgctacaa caaaatcatc
    26581 accgcccaca ggatcacccc cacacacgtg gggaacacat aaactttttt tgtgatttgg
    26641 aaacttatca aggatcaccc ccacacacgt ggggaacact caaacaggtg tgggtatcaa
    26701 ataaatttgt ttaggatcac ccccacacac gtggggaaca cctgtagtta atgactataa
    26761 gatagcctga aacaggatca cccccacaca cgtggggaac acataaactt tttttgtgat
    26821 ttggaaactt atcaaggatc acccccacac acgtggggaa cacctgatgc acctaattgg
    26881 ctctttgcca aactcaggat cacccccaca cacgtgggga acacccaata ttagttcaga
    26941 tgatggcaac aaaataagga tcacccccac acacgtgggg aacaccattg atgaaagagt
    27001 tgcaaagtta tccttggagg atcaccccca cacacgtggg gaacacctct gcttgtattt
    27061 tcttggttgg aacatagtag gatcaccccc acacacgtgg ggaacactag gaattgatcc
    27121 tgtgagagta gattataaag aggatcaccc ccacacacgt ggggaacact gcagctaatt
    27181 gctgccaagc aaattcataa agggatcacc cccacacacg tggggaacac tattgctggc
    27241 taaatatttt aattctatat tcaggatcac ccccacacac gtggggaaca cgaagaaatc
    27301 agttgctcgt tttagaatag gataggatca cccccacaca cgtggggaac acagctactt
    27361 ggggttggct atctgaatgc aattaggatc acccccacac acgtggggaa cacatcaatg
    27421 aattcactag ttgcgcgtac tgataaggat cacccccaca cacgtgggga acactttgta
    27481 tatcacgctg caggagctat ccactcagga tcacccccac acacgtgggg aacacttcta
    27541 aatcatgaaa atttagggta tttaatcagg atcaccccca cacacgtggg gaacacacct
    27601 gccatgtaaa cagttgcccg actagaatag gatcaccccc acacacgtgg ggaacacttg
    27661 ttgggtacct tcaacttcca gccctgtgat aggatcaccc ccacacacgt ggggaacact
    27721 gcagctaatt gctgccaagc aaattcataa agggatcacc cccacacacg tggggaacac
    27781 tccttctcga atcacgccac gcactttgca ataggatcac ccccacacac gtggggaaca
    27841 cattttaatt ctgactggtc tacctaccag catgggatca cccccacaca cgtggggaac
    27901 acagtaaaaa atccttgtta tacccttatt tttaaacttt gatattgcca ttttccatta
    27961 gtttgtataa caactgcaac gtagccttag catcagatag tgcattatgt ggcttggaat
    28021 tcttaatatt ataaaaatct aaaatagttg ccaaacgata attatcaata aatttttccg
    28081 cttttttaac tacaggtaat aaatctaaag tttcattatc cggttctttt aaatttacaa
    28141 atctatagcc ggacatgaga aaggataaat caaactgtaa attatagcca ataatcgtgg
    28201 cagaactaat aaactcagtt agttctctaa gagctctatc taaagtaacc ccctcttttt
    28261 tcaataattc taatgttatg ccggttaatt cagttatcgt cttt
//
