LOCUS       NZ_QSJW01000010        21594 bp    DNA     linear   CON 28-FEB-2024
DEFINITION  Blautia obeum strain AM29-25AC AM29-25AC.Scaf10, whole genome
            shotgun sequence.
ACCESSION   NZ_QSJW01000010
VERSION     NZ_QSJW01000010.1
KEYWORDS    WGS; RefSeq.
SOURCE      Blautia obeum
  ORGANISM  Blautia obeum
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Blautia.
REFERENCE   1  (bases 1 to 153253)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     A genome reference for cultivated species of the human gut
            microbiota
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 153253)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2018) BGI-CNGB, BGI, No. 11, Beishan IZ., Yantian
            Dist., Shenzhen, Guangdong 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina Hiseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/28/2024 19:09:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,731
            CDSs (total)                      :: 3,671
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 10 of 71
            Pseudo Genes (incomplete)         :: 61 of 71
            Pseudo Genes (internal stop)      :: 10 of 71
            Pseudo Genes (multiple problems)  :: 9 of 71
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:03:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 30719
            Orig. end                         :: 52313
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QSJW01000010.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21594
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21594
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21594
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11594](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11594
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     gene            359..694
                     /locus_tag="DW767_RS14420"
                     /old_locus_tag="DW767_14420"
     CDS             359..694
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426510.1"
                     /locus_tag="DW767_RS14420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14420"
                     /product="hypothetical protein"
                     /protein_id="WP_022214380.1"
                     /transl_table=11
                     /translation="MNEFYEAVSNLFEELRCDFGEREYTVQPEEWKEAEKNLKQIQKKL
                     PLHLEKIPEREQNFWNKYLDQLEHFHYEEEQRAYYQGMMDVVEFLINIGAIKKSTNVKR
                     MIEKYAR"
     gene            complement(758..1117)
                     /locus_tag="DW767_RS14425"
                     /old_locus_tag="DW767_14425"
     CDS             complement(758..1117)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524620.1"
                     /locus_tag="DW767_RS14425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14425"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_015524620.1"
                     /transl_table=11
                     /translation="MPKQTDKELGLFFKNARHEQKLTYEELAEKAEMSSRYLKEIENGG
                     RVPSFHKIRKLVRALNVPPEPLFYPNNHTDNLDYQRLLMYLSKCNDEQITAILAIVEAY
                     LRTYKIPTDHDKQDP"
     misc_feature    complement(1504..1518)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.77"
                     /tool="antismash"
     gene            1622..2059
                     /locus_tag="DW767_RS14430"
                     /old_locus_tag="DW767_14430"
     CDS             1622..2059
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541277.1"
                     /locus_tag="DW767_RS14430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14430"
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_015541277.1"
                     /transl_table=11
                     /translation="MEQSSFQDEQTVRHQFDSLCKLALKSEVINYEKHMAYRQKYEVML
                     SELSEKELSRLFIMEEHEMETHRFQVLGYDIEVKDALIAEALQTLTEKKRNVVLLSYFM
                     DMSDADIAREMNLVRSTINEHRRRSLELMRKNMEESANEKK"
     gene            2046..2318
                     /locus_tag="DW767_RS14435"
                     /old_locus_tag="DW767_14435"
     CDS             2046..2318
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004070291.1"
                     /locus_tag="DW767_RS14435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14435"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_015541278.1"
                     /transl_table=11
                     /translation="MKKSKKQKCAFDLLPFHVIEAASTGDTEAIQAVLKHYEGYITVLA
                     TRKMFDEFGQVHYCVDETLRQRLEAKLITKTLGFDTKSYVRKSNQ"
     misc_feature    complement(2675..2690)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.25"
                     /tool="antismash"
     gene            2743..2964
                     /locus_tag="DW767_RS14440"
                     /old_locus_tag="DW767_14440"
     CDS             2743..2964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571651.1"
                     /locus_tag="DW767_RS14440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14440"
                     /product="excisionase"
                     /protein_id="WP_021650362.1"
                     /transl_table=11
                     /translation="MAIKIEKGKIPIWEKYMLTVDEAVQYFGIGEKKIRMLISEHLNSE
                     CCFTVQVGCKSLINRKKFEAFLDQTTSL"
     gene            3069..4283
                     /locus_tag="DW767_RS14445"
                     /old_locus_tag="DW767_14445"
     CDS             3069..4283
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008752734.1"
                     /locus_tag="DW767_RS14445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14445"
                     /product="site-specific integrase"
                     /protein_id="WP_044960653.1"
                     /transl_table=11
                     /translation="MGKTKRDQKRRDKKGRILRNGESQRKDGRYAFVYTDCYGKQKFLY
                     SWKLEPTDSLPTGCRPCLALREKEKNIQRDLHDGIVPYGGNLTVLDLVQKYIGQKKGVR
                     HNTQANYDFVINIIKKEEFGTRRIDKIKLSDAKAWFIKLQADGRGYSSIHSVRGIVRPA
                     FQMAVEDDLLRKNPFEFQLCTVVVNDSVTRQAITKEQEELFLEFIRNDDHYSKYYNGMF
                     ILFKTGLRISEFCGLTVKDIDLQERKINVNHQLQRTRGMQYVIEDTKTSSGTRMLPMTD
                     EVYECFEQIVKNRKKVRVEPIIDGYSRFLFLDKKDMPEVALHWEKHFQWALGKYNRTHE
                     EQMPKITPHVCRHTYCSNMAKAGMNPKALQYLMGHSDIGVTLNVYTHLGLIDAKEEMNR
                     IAKLA"
     gene            4499..4984
                     /locus_tag="DW767_RS14450"
                     /old_locus_tag="DW767_14450"
     CDS             4499..4984
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008703746.1"
                     /locus_tag="DW767_RS14450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14450"
                     /product="low molecular weight
                     protein-tyrosine-phosphatase"
                     /protein_id="WP_118045782.1"
                     /transl_table=11
                     /translation="MIRVLFVCHGNICRSPMAEFIFKDMVNNRGLGDQFYIASAATSTE
                     EIWNGIGNPVYPPAKRELAKHGISCEGKRAVQLKKSDYDKYDYLIGMEERNRRNMLRIL
                     GKDPEKKVSLLLDYADEHGDIADPWYTGNFDITYRDVVRGCEGFLTYLEGKGQIIMN"
     gene            5218..6144
                     /locus_tag="DW767_RS14455"
                     /old_locus_tag="DW767_14455"
     CDS             5218..6144
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541281.1"
                     /locus_tag="DW767_RS14455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14455"
                     /product="DUF5688 family protein"
                     /protein_id="WP_022387991.1"
                     /transl_table=11
                     /translation="MENGYENFVDTLRQSLLKETSYEEEMICYKKAEEYPPTSGDRLLL
                     KNRQKEGVYEVCALYVRDLYDEFQNGWSMENIIQEIMKRLDTLARSECFEKSKNLDSYE
                     KVKGDLFIRLMNVVKYRDELKNAIFRTVGDIALVLYARMGELDGCSTSIKIKKHMLQKW
                     EQDEQSVFNEALLNTYFISPPRIYCWEKLLYNLDYEGENFMNLLFDMSLKKDAIGNCLS
                     TSVRTNGAVAVFLPGVAQRLGKLIGGSFYMVFTSIHEVMIHSEDSADPRKLKEVLAETV
                     EETTPEEDFLTYYVYHYNAETGQFSYY"
     misc_feature    5221..5232
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.53"
                     /tool="antismash"
     gene            6220..6984
                     /locus_tag="DW767_RS14460"
                     /old_locus_tag="DW767_14460"
     CDS             6220..6984
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008703740.1"
                     /locus_tag="DW767_RS14460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14460"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_022387992.1"
                     /transl_table=11
                     /translation="MAYKIVLDAGHGGTDPGAVYNGRNEKDDNLALAQAVGKILEDNGV
                     DVVYTRTEDIYQTPFEKARIANQSGADYFISFHRNSSPEDNQYQGVEVLVYDKSGIKYQ
                     MAQNIVGALGELGFREIGVKERPGLVVLRRTRMPALLIETGFINSDADNALYDEKKDEI
                     AQAIAGAILGTLSEETIEAPLYYRVQTGAFRNRENADRMLYQLTDQGYPAFLLNENDLY
                     KVQVGAFQQIGNAINMEQRLRDAGYSTVIVTK"
     misc_feature    complement(6252..6266)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.71"
                     /tool="antismash"
     gene            7007..7591
                     /locus_tag="DW767_RS14465"
                     /old_locus_tag="DW767_14465"
     CDS             7007..7591
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426493.1"
                     /locus_tag="DW767_RS14465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14465"
                     /product="YdcF family protein"
                     /protein_id="WP_117753389.1"
                     /transl_table=11
                     /translation="MYEEFIKETSKFIFAENKPEKADIIFVPGNGYSQMAERAAQLYAK
                     KYAPFVLPSGKYSISAGRFGGVLTGQKRYNGEYQTEWEFLKDVLMKNGVPADAVLKENQ
                     ATFTWENAKFSRKVTDQAGINIRKAIICCKNYHARRALMYYQRAYPDTEFRVCPCCVDG
                     ITRDNWIESERGIKEVLAEVNRIVTQFSLMM"
     gene            7879..9504
                     /locus_tag="DW767_RS14470"
                     /old_locus_tag="DW767_14470"
     CDS             7879..9504
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426492.1"
                     /locus_tag="DW767_RS14470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14470"
                     /product="hypothetical protein"
                     /protein_id="WP_117753388.1"
                     /transl_table=11
                     /translation="MMKKRKNVQFIAAAALTAALVTSQFSFATVMGDDTATVQVSSLIP
                     NNVTIDQPVPLSDISLPKSDYGTLSWADGSCVPSARVQTYDVVFRPYNAADLAKISGWD
                     GQSEAIYSSVTVVVSSISKDSDYEGDQTEQEAADTENTTQNTEENTEAGTTDNTEENTE
                     TTVPEVTPEVTENPENTENTADSESTEDKSNADTDSTEVTETPDNVITENTEAPAVTVT
                     PSENRDTPEAVETPGPADIAEVTEAPSVTDTPSVTDTPEPTVTPEADKDNIFDGTEKDI
                     TADDRAQSVEEDTEPSDEEKAQIAEKNHTCNGISVSGINLPWYVQFRAASGENYEFTNE
                     AEANVFKSYDFELWDLKNNTEYEIPDGEYLSVTVPVKAGYDYTIEHLLDSGAMETIVPS
                     VEGSTMVFSTHSFSPFGIAGSKALVGEEIEDGSYSSGTTSTATTTPQATAAASTNTGST
                     SGGTANNASNTVSGSANNTSVQASTSENQNSTSDSADQSEADSKGNSVGAVETGDNTPI
                     LPFVIIGIAAAVIVAVLVYLKKKK"
     gene            9575..9925
                     /locus_tag="DW767_RS14475"
                     /old_locus_tag="DW767_14475"
     CDS             9575..9925
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426490.1"
                     /locus_tag="DW767_RS14475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14475"
                     /product="TIGR04086 family membrane protein"
                     /protein_id="WP_022388701.1"
                     /transl_table=11
                     /translation="MKVKAILRSLFLAYLLSGVCLLLLALLVFKLDIGKGPVTVGILVI
                     YVLSCLAGGFLAGKILRQDKYRWGFLVGLCYFVLLAAVSFAVQRKWDMSFQHLVTTFFM
                     CLGGGTLGGMLS"
     gene            10001..10141
                     /gene="scfA"
                     /locus_tag="DW767_RS14480"
                     /old_locus_tag="DW767_14480"
     CDS             10001..10141
                     /codon_start=1
                     /gene="scfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015524633.1"
                     /locus_tag="DW767_RS14480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14480"
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="WP_015541285.1"
                     /sec_met_domain="TIGR03973 (E-value: 3.5e-27, bitscore:
                     87.3, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 4e-27, bitscore: 87.2,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHIKTLNTKNLQNTVKKGGCGECQTSCQSACKTSCTVGNQSCEN
                     K"
     misc_feature    complement(10217..10231)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.83"
                     /tool="antismash"
     gene            10230..11594
                     /gene="scfB"
                     /locus_tag="DW767_RS14485"
                     /old_locus_tag="DW767_14485"
     CDS             10230..11594
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015541286.1"
                     /locus_tag="DW767_RS14485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14485"
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="WP_182279514.1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.3e-28,
                     bitscore: 92.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 1.1e-74, bitscore:
                     244.8, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.9e-15, bitscore: 50.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.4e-13, bitscore: 44.8,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.9e-19, bitscore:
                     62.1, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLIHRYQSNGYNIVLDINSGCIHLVDLVTYEVLPFMEEGLSEQE
                     IVDKLKDQYPEADIRTSVSECEKLKEQGMLFTRDIYENIIDEFTENRQTVVKALCLHIA
                     HDCNLACRYCFAEEGEYHGRRALMSFEVGKKALDFLIANSGSRKNLEVDFFGGEPLMNW
                     QVVKDLVAYGREQEKLYNKKFRFTLTTNGVLLNDEVMEFCNKEMGNVVLSVDGRKEVHD
                     YMRPFRKGAGSYDLIIPKFQKFAESRNQDKYYVRGTFTHHNLDFSKDVLHLADLGFKQI
                     SVEPVVAADTEEYAIREEDIPQIMEEYDALAKEMIAREKAGKGFNFFHFMIDLTGGPCV
                     YKRLSGCGSGTEYLAVTPWGDFYPCHQFVGEEQFLMGNVDEGITHPEIRDKFGKCNVYT
                     KEACKDCFARFYCSGGCAANAYHFQKDINGNYGIGCELQRKRVECAIMIKAALAE"
     aSDomain        10233..10535
                     /aSDomain="Ranthipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     ranthipeptide/SCIFF cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DW767_RS14485_Ranthipeptide_rSAM_RRE.
                     1"
                     /evalue="2.40E-29"
                     /identifier="RREFam024.1"
                     /label="DW767_RS14485"
                     /locus_tag="DW767_RS14485"
                     /protein_end="102"
                     /protein_start="1"
                     /score="92.4"
                     /tool="antismash"
                     /translation="SLIHRYQSNGYNIVLDINSGCIHLVDLVTYEVLPFMEEGLSEQEI
                     VDKLKDQYPEADIRTSVSECEKLKEQGMLFTRDIYENIIDEFTENRQTVVKALCLH"
     gene            11619..14027
                     /gene="secD"
                     /locus_tag="DW767_RS14490"
                     /old_locus_tag="DW767_14490"
     CDS             11619..14027
                     /GO_component="GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426487.1"
                     /locus_tag="DW767_RS14490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14490"
                     /product="protein translocase subunit SecD"
                     /protein_id="WP_117753386.1"
                     /transl_table=11
                     /translation="MKKSKGIVVLLLTAIITVFLCYTAGIGLGPTGTGSAKNIKTGLDL
                     SGGVSITYQAKDSNPSAEDMSDTVYKLQKRVEQYSTEAQVYKEGSDRIAVEIPGVTDAD
                     AILNDLGKPGSLCFITMTDDDGNANFSSTGSGYVLARSLDEIRESGSVVLEGTDVKDAQ
                     GGAFQSDKNSSREYAVSLTLTDEGKTKFADATEANVGKQIAIVYDNQILSAPKVNEAIT
                     GGQAQITGMSSVEEAQNLASYIRIGSLSIELEELRSSVVAAQLGEEAISTSVMAGLIGL
                     VIVIIFMIIMYRLPGVVAGVALILYTAIVLITLNAFDITLTLPGIAGIILGIGMAVDAN
                     VIIYARIQEEIAAGNSVRASIKSGFSKAFSAIFDGNITTLIASLVLMWLGSGTVKGFAY
                     TLALGIVVSMFTALVVSRFVMNALYAVGFHDEKFYGRAKQRKVFNVVGKRKVFFIISII
                     LILSGPVAMAIHHNVDGTALNYALDFSGGTATTVTFNEDMDIKQIDSEVTPVVEEVTGD
                     KNVQPTKVVGTNQVVIKTRTLSQEEREKLDNALVEKFNVDDSLITTESISSTVSSEMRR
                     DAVVAVIVATLCMLAYIWFRFKDIRFASSAVLALLHDVLVVFAFYGISRISVGNTFIAC
                     MLTIVGYSINATIVIFDRIRENTKGSRSNLEEIVNESITQTLTRSMYTSFTTFVMVAVL
                     YIMGVSSIREFAAPLMVGVICGAYSSVCITGALWLVMKRYYKKPVAQAVAAKNTAAPAK
                     QNNNSQDTKSGKKNSDQPKKKNRKRVAERLAAQEAAAKENASKDENKDA"
     gene            14162..15874
                     /gene="recJ"
                     /locus_tag="DW767_RS14495"
                     /old_locus_tag="DW767_14495"
     CDS             14162..15874
                     /GO_function="GO:0008297 - single-stranded DNA
                     exodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426486.1"
                     /locus_tag="DW767_RS14495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14495"
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="WP_118045784.1"
                     /transl_table=11
                     /translation="MEKWMVYNKKADFQKIGSEFGIDPVIARLIRNRDIQDMKEIRSYL
                     YGTLAEIPSPWKMKDMERAVQILQKKITQKKKIRIIGDYDIDGVTATCILLKGLKRLNA
                     NVDTYIPDRVKDGYGMHEQLIDKALEDGIDTILTCDNGIAAAAEIEYAKKEGLTVIVTD
                     HHDIPFRDTEDGRIWIIPKADAVVNPKQNDCLYSNKNICGAVVAWKLIWALYERLGIDS
                     DEMWDFLELAAIATVGDVMDLQGENRIIVKEGLKKLSSTSFEGLKALICVNNLEGAEIT
                     AYHVGFVIGPCINASGRLDTAARSLELLLADNMEDAMKLADDLYDLNQSRKAMTEQGKG
                     QAIQSIEENNLGKDRVLVVYLPDCHESLAGIIAGRIREAYNKPVFVLTKGADGVKGSGR
                     SIEAYSMYEELVKCSDLLTQFGGHPMAAGLSMEEKNIELFRRRLNDNCTLTEQDLIPKI
                     MIDVPMPISYLSKKLTEQLKVLEPFGKGNSKPLFAQKNLRAVGIRVLGRNRNVAKMLLI
                     DENGIKMDAVYFGEAQEFVDFVQAHDTISVTYYPEINVFQGRENLQVVIKNYC"
     misc_feature    complement(14174..14190)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.87"
                     /tool="antismash"
     misc_feature    complement(14200..14209)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            complement(16439..17500)
                     /locus_tag="DW767_RS14500"
                     /old_locus_tag="DW767_14500"
     CDS             complement(16439..17500)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0043107 - type IV pilus-dependent motility
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426485.1"
                     /locus_tag="DW767_RS14500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14500"
                     /product="PilT/PilU family type 4a pilus ATPase"
                     /protein_id="WP_022388025.1"
                     /transl_table=11
                     /translation="MNKEQTLEFLSKAADLHASDIFIIAGRPLSIKTDGRLSTYGDRLM
                     PEQTSEILEAIYQMANNRDISRLHNTGDDDFSFSIPGLSRFRINAYKQRGSLAAVIRVI
                     AFQLPDPAELSIPEDVMSIADLTKGMVLVTGSAGSGKSTTMACLIDRINHSREGHIITL
                     EDPLEYLHRHDRCIVSQREICTDTENYITSLRATLRQSPDVILLGEMRDHETIQTAMTA
                     AETGHLILSSLHTLGAANSLNRIIDVFEPSQQHQIIMQLSMVLQAVISQQLVPDVNGKN
                     IPVFEIMRLTPAIRNMIRDNKIHQIDGVISSSPGQMRSMDQSLFELYKNGRITKETAIN
                     YAMNPEMLRRRLG"
     gene            complement(17493..17987)
                     /locus_tag="DW767_RS14505"
                     /old_locus_tag="DW767_14505"
     CDS             complement(17493..17987)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426484.1"
                     /locus_tag="DW767_RS14505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14505"
                     /product="hypothetical protein"
                     /protein_id="WP_022388024.1"
                     /transl_table=11
                     /translation="MKDHNSFFTATGIPSLFLIFSVLCLAVLSLLTLGNSRSELSTARN
                     SMQQTEDYYNACSQASTVINEIQTELTDAYRQATDQKNYLALVGQFCKDHSELTFDEEK
                     QTLLFAESLSDTQQLTVCLKVLYPEKSGDSLIQILQWKTDTTASWTPDTSQSVYKGGTH
                     E"
     gene            complement(17984..18439)
                     /locus_tag="DW767_RS14510"
                     /old_locus_tag="DW767_14510"
     CDS             complement(17984..18439)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426482.1"
                     /locus_tag="DW767_RS14510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14510"
                     /product="hypothetical protein"
                     /protein_id="WP_117592932.1"
                     /transl_table=11
                     /translation="MKKISAHSKTSLFLMEMIFVLLFLALSSAACIRIFAAAKKNHIQA
                     QEWRHIQTLTTSVGEILEDSDGTAKSFVSLFPDGQIQDNLIEWYYDSSWQLCSDSQASY
                     KMELTLHETANSRQGTLTFYHATNDIQIYTIDLVFPIIENSDKEASS"
     gene            complement(18436..18933)
                     /locus_tag="DW767_RS14515"
                     /old_locus_tag="DW767_14515"
     CDS             complement(18436..18933)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426481.1"
                     /locus_tag="DW767_RS14515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14515"
                     /product="DUF4860 domain-containing protein"
                     /protein_id="WP_055055556.1"
                     /transl_table=11
                     /translation="MKKRLITRHPVAELASLLLFGIFVLFLLLMLLFSARIYQQTVKNT
                     NAENTLGTAVSYLTTKFRQHDTVNGIFTGKLDNLSALCFRDTLNDQDYITYIYLDQGNL
                     KELFTSDSSSANASAGTTIAQLSDFQISESRPGFYSFELKDSEGNKETFYLHQNSVSKE
                     AS"
     gene            complement(18930..19292)
                     /locus_tag="DW767_RS14520"
                     /old_locus_tag="DW767_14520"
     CDS             complement(18930..19292)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426480.1"
                     /locus_tag="DW767_RS14520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14520"
                     /product="hypothetical protein"
                     /protein_id="WP_118045785.1"
                     /transl_table=11
                     /translation="MELFDSHRKKFLRRFSLLLPLCFLILISSIFFISVSFASDETLHK
                     EQQALEQALENGAIRSYAMNGQYPESLDQILNDYHITYDRSRFVVEYTPNGSNLLPYIS
                     VILLSDTAGHGKRAAK"
     gene            complement(19305..20348)
                     /locus_tag="DW767_RS14525"
                     /old_locus_tag="DW767_14525"
     CDS             complement(19305..20348)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015526156.1"
                     /locus_tag="DW767_RS14525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14525"
                     /product="type II secretion system F family protein"
                     /protein_id="WP_005426479.1"
                     /transl_table=11
                     /translation="MKYTLTARELSNFFGQLGMLIHSGISVTEGLAILQDESQTDTDRE
                     IITALLTSMEETGSLTQAMETSGRFPHSSVSYIKTGEETGCLDEILNSLTLHYEQEQEV
                     SEQIRSAVTYPLIMLGMMGIVIVVLLVKVLPVFQQVFQQMGMEMNTLSLGLLKAGSILS
                     NYSGIFLILVVLLVGLILFLSLSEKGHIYLRNAAYHLPVFRDIPLAADYGRLAQGLSLG
                     LKSGLTPDTSLELSAEMVSHPLILKRLEETGHLLEEGTPFYQALTDSKLFTGMEGRLIS
                     VGFQSGSADEALNQLSVKYREKAVDLISEAISIVEPTIVIILSLLVGLVLLSVMMPLLG
                     ILSDIAL"
     gene            complement(20367..21293)
                     /locus_tag="DW767_RS14530"
                     /old_locus_tag="DW767_14530"
     CDS             complement(20367..21293)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005426478.1"
                     /locus_tag="DW767_RS14530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_14530"
                     /product="transglutaminase-like domain-containing protein"
                     /protein_id="WP_233435752.1"
                     /transl_table=11
                     /translation="MNRFIRLRLLAMILCLPFLLIFISGCGSSSQKKDEPPVYSPLQVL
                     VPEATGKETLGSSPMILDVSNISQGYFIAQSDSSDLTCSLQIISPSGVLYSYFIAPGES
                     ATVTFTEGSGDYTITGYQQVQGDQYAALYSETVTVQLENDFLPFLYPNQYVNFTPDSKA
                     SQLALSLIDEDTVDVDALQQIYDYVVSNLTYDYEKADTVTTGYLPDVDETLKTGTGICF
                     DYAALTTAMLRSCDIPCKLQIGYAGDIKHAWIDVYIRSKGWVNQAVSFKGDTWTLMDPT
                     FDSNSDDKEAIQDYIGDESNYTVQFTR"
     regulatory      21469..21552
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
ORIGIN
        1 cgtagtcggg aacgaaacgt gtgccttgtt caattcgcag gattgccaga tcattaacat
       61 catatcctgc aagttgtaat ttggcagcga gtgttttctg agtaagatta tgagcctttc
      121 gtaattcttt tacccgttgt cctattctgt ttttactgtt cgttttttta tcccaataaa
      181 taatcattct gatcctcaaa agtttctaaa gatgaagtat tattattgat tttaaggaaa
      241 aatattgtta ctatacttct aaagatgaag tttttggaaa gtttatttga tttttgaaat
      301 aagaaaatga taatgctgcc tgtaatgaga aataattcta atgagaggtg gaaagaaaat
      361 gaatgaattt tatgaagcag tatcgaattt atttgaggaa ttgcgctgtg acttcggaga
      421 aagagaatat acagtacagc cggaagaatg gaaagaagca gagaagaatt tgaaacaaat
      481 acaaaagaag ctgccactac atctggaaaa aatcccagag cgtgagcaga atttctggaa
      541 taaatatctg gatcagttag aacatttcca ttatgaagag gagcagcggg cttattacca
      601 gggaatgatg gatgtagttg agtttcttat taatataggg gcaataaaga aatccacgaa
      661 tgttaagaga atgatagaaa aatatgcacg ttaagagtgg cggtatggga aaccataccg
      721 cttcttcaga ataattcaga tagaattcaa atgaatttca gggatcttgt ttatcgtggt
      781 ctgtaggaat tttgtatgtg cgcaggtatg cttctacgat ggcaaggata gcggtaattt
      841 gctcatcgtt gcattttgac aggtacatga gcaggcgttg ataatcaaga ttatctgtat
      901 gattgtttgg ataaaacaat ggttcaggag gaacatttaa agcgcgtacc agttttctga
      961 ttttatgaaa actgggaact cggcccccat tttcaatttc ctttaaatat cggctggaca
     1021 tttctgcttt ttcagctaat tcttcataag tcaatttttg ctcgtgtcgg gcgttcttaa
     1081 aaaacaatcc cagttcttta tctgtttgtt ttggcatatg atacacctcc atgtttagtg
     1141 tatagttccc tttcttgaaa gaaaatgaac taatatttca ctaaaaaaga gggtgatatt
     1201 tcacttttta aaagacatat aaaattctga atttccgtaa aacagatccg gaggtatagg
     1261 aaagattaag aattttattg tctggtatca tatccgtcat tacgtgacgg atgaaataga
     1321 taaatagttc aaaaaagcaa ataaatttct ttacctcaaa aagtgaatta tatgccacaa
     1381 aaaatgatgg caaaatatta tcttttgata taaatagcgt ccgatgggct aaaaactacc
     1441 cattaggacg ttttttatat acctcaaaat acaggaaaaa caattttctc gtatttatta
     1501 agaaattttt taaaaatttc ttcccacacc ccgacaaatg cactcatccg tttgggatat
     1561 gtgtgaaggg gaagcaagaa ctttgcttat tgcctaccgg cggggaagga ggtgaactct
     1621 tatggagcaa tcctcttttc aagatgagca gacagtcaga catcagtttg attctctgtg
     1681 caagctggca ttgaaaagtg aagttattaa ttatgaaaag catatggcat atcgccagaa
     1741 gtatgaagtg atgttgtcag aattatcaga aaaggagttg agcagacttt ttataatgga
     1801 agagcatgaa atggaaacac atcgttttca ggtcctgggt tacgacatag aagtcaaaga
     1861 tgcattgatt gctgaagcac tgcagacact tactgaaaag aaaaggaatg ttgtgttatt
     1921 atcatatttt atggatatga gtgatgcaga cattgccaga gaaatgaatc ttgtacgcag
     1981 cacaattaat gagcatcgta gacgatcact ggaactgatg agaaaaaata tggaggaatc
     2041 tgcaaatgaa aaaaagtaaa aaacagaaat gcgcatttga tttgctgcca ttccatgtta
     2101 ttgaggcagc atcaactggt gatactgagg caatccaggc agtgttgaag cattatgaag
     2161 ggtacataac agttttggct accagaaaaa tgtttgacga atttggacag gtgcattact
     2221 gtgtagatga aactctgcgt caacgcctgg aagcaaaact gattactaag accttgggat
     2281 ttgatacgaa atcatatgta aggaaaagta atcagtaaag ggagtattta atatagattc
     2341 cttttcccct tcaggaattt ttgtaccttg aaaattgtat attgttttac atacaggacg
     2401 tgaagatatg tagagccact aggtaaatcc gccatgatat atctgctctg ttaatggagt
     2461 aaatacgagg aaatgctgaa atataacatt gaagtaaagg tatggagcga gaagaatttg
     2521 acaaaatgtg cagcagctgc acagggcgac gaagcatatc tgtgataatg atacttccag
     2581 aaaaaagctg gtcatattta atgacggtgc aaaaccgatg tgggcagagt actgaactgc
     2641 cacctgtatt gtaattttat ctgccgatga cagtgtataa aattgtaaat tgtcatgggc
     2701 agataaaaat gttttgtcca aagagaaaag gaggagagaa gagtggcgat taaaattgaa
     2761 aaaggtaaga ttccaatttg ggaaaaatat atgcttacgg tggatgaagc agtgcaatat
     2821 ttcggaatag gtgaaaagaa aataaggatg cttatttcgg aacatctaaa ttcagaatgt
     2881 tgctttacag tccaggtggg gtgtaagtca ttgattaacc gtaagaaatt tgaggccttt
     2941 ctggatcaga ctacgtcttt gtaaaaaata tacgaacaat ttagcacttt aaagtggaaa
     3001 tgttagccct ggtatgatat aatacctata tcgtgctagg gcttcttcgt agaaaggggc
     3061 gaagacgttt gggtaaaaca aaacgtgacc aaaaacgacg agataaaaaa ggtcgaattt
     3121 tacgaaacgg agaaagtcag agaaaagatg gaagatatgc gtttgtatat acagattgtt
     3181 atggaaagca gaagtttttg tatagttgga aattagagcc aacagattct ctgccaactg
     3241 gatgcagacc atgcttagct ctaagggaaa aagaaaaaaa tatccaaaga gatttacatg
     3301 atggtatagt accttacgga ggaaatttaa cagttttgga tttggttcaa aaatatattg
     3361 gacaaaaaaa gggggttcgt cataatactc aggcgaacta tgattttgtg atcaatataa
     3421 taaaaaaaga agaattcgga accagaagaa tagataaaat aaaattgtcg gatgcaaaag
     3481 catggtttat taagctgcaa gcagatggaa gaggatacag ttccattcac agtgtgcgtg
     3541 gaattgtaag acctgcattt cagatggcag ttgaagatga tttactgcgc aagaatcctt
     3601 ttgaatttca attatgtaca gttgtcgtaa atgacagtgt tacaagacag gcaattacaa
     3661 aagaacagga agagttattt ctggagttta tccgaaatga tgaccattac tcaaaatact
     3721 ataatggaat gtttattttg tttaagactg gacttcgtat ttctgagttt tgtggattga
     3781 cagtgaaaga tattgatctt caggagagaa aaatcaatgt gaatcatcag cttcagagaa
     3841 ccagaggaat gcagtacgtc attgaagata ccaaaacttc aagtggaaca cgaatgttgc
     3901 cgatgacaga tgaagtttat gaatgttttg aacagattgt gaaaaaccgt aaaaaagtaa
     3961 gggttgagcc gattatagat ggatatagtc gatttttatt cctggataaa aaagatatgc
     4021 ctgaggtagc actccattgg gaaaaacatt ttcagtgggc gttaggaaag tataatcgta
     4081 ctcatgagga acaaatgcca aagatcacgc ctcatgtatg taggcataca tattgttcca
     4141 atatggcgaa agctggaatg aatccgaaag cactccaata tttaatggga cattctgata
     4201 taggggttac gttaaatgta tatacgcatc tgggattaat tgatgcaaaa gaagagatga
     4261 ataggattgc aaaactggca tagtatgata aaataataga aaaaagaatt aaaaataatc
     4321 tgattataag gttcttagag agcctgtttt ccaggctggt tattactaag aagttactaa
     4381 atttggataa gaaaatatac gaatttatgc tgtgatatac aggaaaatga caggattgaa
     4441 gattatcgga aaatgcctgt aaacagcgta aatacagcat ttcaaggagt tttaagcaat
     4501 gataagagtg ttatttgtct gccacggcaa catctgtcgt tctccaatgg cagaatttat
     4561 atttaaggac atggtcaata accgtggact aggtgaccag ttctacatcg cctctgcggc
     4621 gacgagtaca gaagaaatct ggaatggaat cggtaacccg gtatatccac cggcgaagcg
     4681 tgaactggcg aaacatggaa tttcctgtga agggaaaagg gcagtacagc ttaaaaaatc
     4741 agattatgac aaatatgatt atctgattgg aatggaagag cgaaacagaa gaaatatgct
     4801 tcgaattcta ggcaaagatc cggaaaagaa agtgagcctt ctgctggatt atgcggacga
     4861 acacggggat atcgcagatc catggtacac aggaaatttt gacattacat atcgcgacgt
     4921 agtcagggga tgcgagggct ttctgacata tctggaaggc aaagggcaga ttattatgaa
     4981 ttaaactgac ctgatctgaa ttttattcta aagtatttta taataagaaa tgttataaaa
     5041 acaattgtcg atatccacga attttgtcga acgaattttc tttacagaaa caatattatg
     5101 cggtatcctc tagatacagc aactcttgaa gggagcatct gcttccttct ttttttcaaa
     5161 tctatttaag tcatgggcag atcgcccgaa taattcagga aagatgagga attgaatatg
     5221 gaaaacggtt acgaaaactt cgtggacact ttgagacaga gtcttcttaa ggaaacttct
     5281 tatgaagaag aaatgatctg ttataagaag gctgaggaat atcctccgac ttcgggtgac
     5341 agactgcttt tgaaaaacag acagaaggaa ggcgtttatg aagtctgtgc actttatgtg
     5401 cgagatctgt atgatgaatt tcaaaatgga tggagcatgg agaatatcat acaggaaatt
     5461 atgaaaagat tagatacgct tgctcgttcc gagtgttttg agaaaagtaa aaatctggac
     5521 agttacgaaa aggtaaaggg agatctgttt atccgcctga tgaatgtggt taaatatcga
     5581 gatgaactga agaatgcaat ttttcgaacc gttggggata ttgcactggt attatatgcc
     5641 cggatgggag aactggatgg atgcagtacc agcattaaaa taaaaaaaca tatgttacag
     5701 aaatgggagc aggatgaaca gtcagtgttt aatgaggcac ttttgaatac gtattttatt
     5761 tcgccaccaa gaatttattg ctgggagaaa cttctatata atttggatta tgaaggcgag
     5821 aattttatga atctgctgtt tgatatgtct ttgaagaaag atgcaatagg aaattgtctg
     5881 agtacatctg tccggaccaa tggagcagtg gctgtttttt tacccggagt tgcgcagcga
     5941 ttggggaaac ttattggtgg cagtttttat atggtgttta caagtattca tgaagtaatg
     6001 atacacagcg aagatagtgc agatccaaga aagctaaaag aggttctggc agagactgta
     6061 gaggaaacga caccggaaga agattttctt acctattatg tgtaccatta caatgcggaa
     6121 actggtcagt tcagctatta ttgaagcaat ctgattatcc cgtatgcttt ttatcagtgt
     6181 gtgcatatac taattaaaaa gcagtcagga gatacaaaat tggcttataa aattgttttg
     6241 gatgcgggac atggcggaac ggatccaggt gctgtatata atggaagaaa tgaaaaagat
     6301 gataatcttg cacttgcaca agcggtagga aaaatccttg aagacaatgg tgtggatgtg
     6361 gtatatacta gaacagaaga tatttaccag acgccatttg agaaggcaag aatcgcaaat
     6421 cagtcaggtg cagattattt tatctctttt catcggaata gcagccctga agataatcaa
     6481 tatcagggcg tagaagttct ggtatatgac aaaagtggaa ttaagtatca gatggcacaa
     6541 aatattgttg gagcactggg ggaacttgga ttcagagaaa taggagtaaa agaacgtccg
     6601 ggactggtcg ttctgcgaag aaccagaatg cctgctcttc tcattgaaac cggatttata
     6661 aactcagatg cggataatgc attatatgat gagaaaaaag atgaaatagc acaggcgatt
     6721 gcaggcgcaa ttctaggaac gttatcggaa gaaacgatag aagctccttt gtattatcgg
     6781 gtacagaccg gcgcatttcg gaacagagag aatgcagacc gtatgcttta tcaattgaca
     6841 gatcagggat atccggcatt tctgttgaat gaaaatgatt tatataaagt acaggttggt
     6901 gcatttcagc agatcggaaa tgcaataaat atggaacaac gcctcagaga tgcaggatat
     6961 agtacggtca ttgtaacaaa ataaaccaaa agagaaggta tcgaatatgt acgaagagtt
     7021 cataaaagaa acaagtaagt tcatttttgc agaaaataag ccagagaaag cggatattat
     7081 ttttgtaccc ggcaatggtt attcacagat ggcagagaga gcggcacagc tgtatgcgaa
     7141 aaaatatgct ccatttgtac tgccaagtgg aaaatacagt atttctgcag gcagatttgg
     7201 cggagtactg actggtcaga aacggtacaa tggagagtat cagacggaat gggaattttt
     7261 aaaggatgta ctgatgaaga atggtgtgcc ggcggatgct gttctgaagg aaaatcaggc
     7321 gacatttacc tgggaaaatg caaagttttc cagaaaagtt acagatcagg caggtattaa
     7381 tataaggaag gcaattattt gttgcaaaaa ttatcatgcc agaagagctt taatgtatta
     7441 tcagagggca tatccggaca ctgagtttcg ggtatgccca tgttgtgttg atggcattac
     7501 cagagataat tggatagagt ctgagagagg aataaaagaa gttcttgcag aagtaaacag
     7561 aatagtcact caattctcac taatgatgta atcttgttaa atataaaaaa aataatttgg
     7621 gggtgtcgaa aaaagtagaa ctgtgatata atgcttgtgt cgtaaaataa aatattgtgt
     7681 tacaaattag ttacgaaaag ataaaagttt catatacgac aaaatagata tttttatatt
     7741 acagtactta aattcgaatt atatatgata tagaaacaag ttacattttt ggtttaaaga
     7801 ttacataaat aatatgaagc tgccggcata taatggcttt gtctggcagt aatgaatata
     7861 gattgaggtg tgaggattat gatgaaaaag aggaagaacg tgcagtttat tgctgctgca
     7921 gcacttaccg cagcacttgt aacaagtcag ttttcatttg caacagtaat gggagacgat
     7981 acagcgacag tacaggtcag cagtctgatc ccgaataatg ttacgattga tcagccagtt
     8041 cctctttcag atatttcact tccgaagagt gattatggaa cactttcctg ggcagatggg
     8101 tcttgtgtac cgtcagcgag agtgcagact tatgatgttg tatttcgtcc gtataatgct
     8161 gctgatctgg cgaagatttc tggttgggat gggcagtcag aggcaattta cagcagtgtg
     8221 acagttgttg taagcagtat cagtaaggat tcagattatg agggggatca gacagagcag
     8281 gaagctgcag atactgagaa tacgacacaa aacacagaag aaaacacaga ggccggcacg
     8341 acagataata ctgaagaaaa tacggaaact actgttccgg aagtaactcc ggaagtaacg
     8401 gaaaacccgg aaaatacaga gaacacagca gactctgagt ccacagagga taagagtaac
     8461 gcagatacag acagcacaga agtgacggaa acaccggata atgttattac tgagaatacg
     8521 gaagcaccgg ctgtaacagt aactccgtca gaaaatagag atacaccaga ggccgttgag
     8581 acaccgggac ctgcagatat cgcagaagtt actgaggcac cgtcagtgac agatacaccg
     8641 tcagtgacag atacaccgga acctacagtg actccggagg ctgataaaga caatattttt
     8701 gatggaacag agaaagatat cacagcagat gaccgagctc agtcggttga ggaggacaca
     8761 gagccgtctg atgaagaaaa agcacagata gcagaaaaaa atcacacatg caatggcatt
     8821 tctgtatcag ggatcaatct tccatggtac gtacagttca gggctgcaag tggtgagaat
     8881 tatgaattta ccaatgaagc agaagcaaat gtattcaaat cttatgattt tgaattatgg
     8941 gatctgaaaa acaatacaga gtatgagatc ccagatggtg aatatctgag tgtgacagtt
     9001 cctgttaagg ccggatatga ttatacaatt gagcatcttc tggacagtgg tgctatggaa
     9061 acaatcgtgc caagtgttga gggcagtaca atggtattca gtacacactc tttcagcccg
     9121 tttggaattg caggaagcaa ggcacttgta ggagaagaaa ttgaagatgg aagctattct
     9181 tccggtacaa cttctaccgc gacaacgact ccgcaggcga cagcagcagc ttccacaaat
     9241 accggcagta catctggcgg taccgcaaat aatgcaagta atacagtatc cggttcagcg
     9301 aataatacat ctgttcaggc atccacatct gaaaatcaga acagtacttc tgactctgct
     9361 gatcagagtg aagcagacag taaggggaat tctgtaggag ctgttgagac tggagataat
     9421 actccgatcc ttccgtttgt gatcattggc atcgcagctg cggtaattgt agcagtactc
     9481 gtttatctta agaagaaaaa ataatatttt gcatagcatt ttgcacatat gaagcaaagc
     9541 tcttccatat atttcaatat gggagggctt ttttatgaag gtaaaggcaa ttttgagatc
     9601 attgtttctg gcatatcttc tgtcgggtgt ctgcctgctc ctgctggcat tactggtatt
     9661 caaacttgac atagggaaag ggccggttac ggtaggaatt ttagtgattt atgtgctgtc
     9721 ctgcctggca ggaggatttt tggcaggaaa gatacttcgt caggataaat atcggtgggg
     9781 atttctggta ggcttatgtt attttgtgtt acttgcagct gtttcttttg cagtacagag
     9841 aaagtgggat atgagcttcc aacatctggt gactacattt tttatgtgtc ttggaggagg
     9901 aacccttgga gggatgcttt cctgataaaa aaatgctttt aattaggctg attttatgct
     9961 atactatgcc cagataatta tacataagga gggatatata atggaacata tcaaaacatt
    10021 aaatacaaag aacctgcaga acacagtgaa aaaaggtgga tgcggtgaat gtcagacatc
    10081 ttgccagtca gcatgcaaaa cttcctgtac tgtaggaaat cagagctgcg agaacaaata
    10141 agcaggttca gaacattcag taagcagcgg agtgaaatcc gctgcttatt cttatgaaca
    10201 aaaagttaca ggaaaggatt ttcagaaaga tgagtctgat tcatagatat cagagcaatg
    10261 gctataacat tgttctggat attaacagtg gatgtattca tctggtagac cttgtgacat
    10321 acgaagttct tccttttatg gaagagggac tttcagagca ggagattgtt gacaaattaa
    10381 aagatcagta tcctgaggct gatatccgta cttctgtttc cgagtgtgag aaactgaaag
    10441 aacagggtat gttgtttacc agagatatat acgaaaatat tattgatgaa tttacagaga
    10501 atcgacagac agtagtaaag gctttgtgcc tgcacattgc ccatgattgt aatctggcct
    10561 gtcgatactg ttttgccgaa gagggagaat atcatggaag aagagcactg atgtcttttg
    10621 aagtgggtaa gaaagctctt gatttcctga ttgccaattc cggatccaga aagaacctgg
    10681 aagtggattt cttcggagga gagcctctga tgaactggca ggttgtcaaa gacctggtgg
    10741 catacggaag agagcaggag aaactttata ataaaaaatt ccgttttaca ctgacaacga
    10801 acggtgttct tctcaatgat gaagttatgg agttctgtaa taaagaaatg ggaaatgttg
    10861 ttctcagtgt ggacggacgt aaagaagttc atgattatat gagaccgttc cgtaagggcg
    10921 caggaagtta tgatctgatc attccgaaat tccagaaatt tgcggaatcc agaaatcagg
    10981 acaagtatta tgtgcgtggt acatttacac atcataatct cgatttttca aaagatgttc
    11041 tgcaccttgc agatcttggt ttcaaacaga tttctgttga accggtagtt gcagctgata
    11101 cagaggaata tgcaatcaga gaagaggata ttcctcagat catggaagaa tacgatgcac
    11161 tggcaaaaga aatgatcgcc agagaaaaag ccggaaaagg tttcaacttc ttccacttta
    11221 tgattgacct gaccggtgga ccttgtgtct acaaacgtct ctcaggatgt ggttcaggaa
    11281 ccgagtatct tgcagtaact ccttggggtg atttttatcc gtgtcatcag tttgttggtg
    11341 aagagcagtt ccttatggga aatgtggatg agggaatcac acatccggag atccgtgata
    11401 agtttggtaa atgtaatgtt tacacaaaag aagcttgtaa agactgcttc gcaagatttt
    11461 actgcagtgg tggctgtgct gccaatgctt atcattttca gaaagatata aatggcaatt
    11521 atggtatcgg atgcgaactt cagcgtaaga gagtggagtg cgcaatcatg ataaaggccg
    11581 cattagcgga ataaaataat gcaagaaggg aaagaacaat gaagaaaagc aaaggaattg
    11641 ttgtgctgct tctgaccgcc attatcacag tctttctgtg ttacacggcc gggattggcc
    11701 tcggaccaac aggtaccggt tctgcaaaaa acattaagac cggcctggac ctgtctggtg
    11761 gtgtaagtat cacctatcag gcaaaagaca gcaacccaag tgcagaagac atgtcagata
    11821 ctgtttataa actccagaag cgtgttgaac agtacagtac agaagcacag gtgtacaaag
    11881 aaggaagcga ccgtatcgct gtagagattc ctggtgttac agatgcagat gcgattctga
    11941 atgaccttgg aaaaccgggt tctctgtgtt ttatcacaat gacagatgat gacggtaatg
    12001 caaacttctc cagtacagga agcggttatg tactggcaag aagtctggac gagattcgtg
    12061 aatccggatc cgtcgttctg gaaggtacag atgtaaaaga tgcccagggt ggtgcattcc
    12121 agtctgacaa aaacagctcc agagagtatg cagtcagcct gacacttaca gatgaaggta
    12181 agacaaaatt tgcagatgct acagaagcaa acgtaggaaa acagattgcg atcgtttatg
    12241 acaatcagat cttaagcgca ccgaaggtaa acgaagcaat cacaggtgga caggcacaga
    12301 ttactggtat gtccagtgtg gaagaagcac agaatcttgc ttcctatatc cgtatcggtt
    12361 ctctgagcat cgaactggaa gaacttcgtt ccagcgtagt tgctgcacag cttggtgaag
    12421 aagcaatctc caccagtgtt atggctggtc tgatcggtct tgttattgta atcatcttca
    12481 tgattattat gtatcgtctg ccgggtgttg ttgccggtgt ggcactgatc ctgtatacag
    12541 cgatcgtact cattacattg aatgcatttg acatcacact gactcttccg ggtattgcag
    12601 gtatcattct tggtattggt atggcggttg atgcgaacgt tatcatttac gcacgtattc
    12661 aggaagaaat cgcagccgga aactctgtaa gagcttctat taaatccggt ttctcaaaag
    12721 cgttcagcgc aatcttcgat ggaaacatca caaccctgat cgcatctctc gtgctgatgt
    12781 ggcttggttc cggtactgtt aagggctttg cttatacact ggctcttggt atcgtagttt
    12841 ccatgtttac agctctggtt gtatcacgtt ttgttatgaa tgctctttat gcagtaggat
    12901 tccatgatga gaaattctac ggtcgtgcaa aacagcgtaa agtattcaat gttgttggaa
    12961 aacgaaaagt atttttcatt atttccatca ttctgatctt aagtggtccg gttgcaatgg
    13021 caatccatca caacgtagat ggaacagctc tgaactatgc acttgacttc tcaggtggta
    13081 ctgcaacaac tgtaacattc aacgaagaca tggatatcaa gcagattgac tctgaagtaa
    13141 ctcctgtcgt tgaagaagtt acaggtgata agaatgtaca gccgactaaa gttgtaggaa
    13201 caaatcaggt agttatcaag acgcgtacgc tttctcagga agaacgtgag aaactggata
    13261 atgcacttgt tgagaaattt aatgtagatg attctctgat cacaacagaa agtatttctt
    13321 ctacagtaag ttccgagatg agaagagatg cagttgttgc cgtgattgtg gctacactct
    13381 gcatgcttgc ttacatctgg ttccgtttca aagatatccg tttcgcaagc agtgcagtac
    13441 ttgccctgct gcatgacgta ctggttgtat ttgcattcta tggaatttcc agaatttctg
    13501 taggtaatac cttcattgcc tgcatgctta ccatcgtagg ttattctatc aacgcaacga
    13561 tcgttatctt cgaccgtatt cgtgagaata cgaagggaag cagatcaaac cttgaagaga
    13621 tcgttaatga aagtatcaca cagacactta caagaagtat gtacacttct ttcacaactt
    13681 tcgtaatggt agctgttttg tacatcatgg gtgtatcttc tatacgtgag ttcgcagctc
    13741 ctctgatggt aggtgttatc tgtggagctt actcttctgt atgcatcaca ggtgctctgt
    13801 ggctggtaat gaaacgctat tataagaaac ctgttgcaca ggctgtagca gcaaagaata
    13861 ctgcagctcc tgcaaaacag aataataaca gccaggatac aaaatccgga aagaaaaatt
    13921 cagatcagcc gaaaaagaaa aaccgcaaga gagtagcaga acgtctggcg gcacaggaag
    13981 cagcggcaaa agaaaatgct tccaaagatg aaaataagga tgcataatcc gaaacataaa
    14041 aagtaacaat taagttgctg tgaacggagt gaacagtaac acatctcaga tcccgggaca
    14101 gactgctgcc ccgggatttg tgttttaata atggataggt tgataaacag agaggatcat
    14161 tatggaaaag tggatggtat ataataagaa agcagatttt caaaaaatag gcagtgaatt
    14221 tggaattgat cctgtgatag cgagattgat acgaaaccgt gatatacagg atatgaaaga
    14281 gattcgttcc tatttatatg gaacacttgc ggaaattcca tccccatgga agatgaagga
    14341 tatggaacgt gcagtgcaga tccttcagaa aaaaattacg cagaaaaaaa agatccgaat
    14401 catcggagat tatgatatag atggcgtgac agctacctgc attttgttga aaggtctgaa
    14461 acgacttaat gcaaatgtgg atacttacat tccggacaga gtaaaagacg gatatggaat
    14521 gcatgagcag ctgatcgata aagcactgga agatggaatt gatacgatac tgacctgcga
    14581 taatgggatt gcagctgcgg ctgaaataga atacgcaaaa aaagaaggac tcactgtgat
    14641 cgttacggat catcatgata ttcctttccg cgatacagag gatggaagaa tctggatcat
    14701 tccgaaagca gatgcagtgg tgaatccgaa acagaatgac tgtctgtatt cgaataaaaa
    14761 tatctgcggg gcggtggttg cgtggaaact gatctgggcg ttatatgaaa gattggggat
    14821 tgacagtgat gagatgtggg attttcttga attggcagca attgcaacag taggtgatgt
    14881 catggatctg cagggagaga acaggatcat tgtaaaggaa ggactgaaaa aactttcttc
    14941 tacttctttt gaagggctga aagcactgat ttgtgtgaat aatcttgaag gtgcagagat
    15001 tacggcatat catgtagggt ttgttattgg cccatgtatc aatgcaagcg gacggcttga
    15061 tacagcagca agatctctgg aactgcttct tgcggataat atggaagatg caatgaagct
    15121 tgcggatgat ctgtatgatc tgaatcagag cagaaaagcc atgacagagc aaggaaaagg
    15181 acaggcgatt cagagcattg aggaaaataa tctcggtaag gaccgagtgt tggtagtgta
    15241 tcttccagac tgtcatgaga gccttgctgg tattattgca ggacggatcc gtgaagcata
    15301 taataagccg gtgttcgtac tgacgaaagg agctgacgga gtaaagggaa gcgggcggtc
    15361 gatcgaggca tattctatgt atgaggaact ggtgaaatgc agtgatctgc tcacgcagtt
    15421 tggcggtcat ccgatggcag ccggactttc aatggaggaa aaaaatatag aacttttccg
    15481 cagacgtctg aatgacaact gtactctcac ggagcaggat ctgattccta aaattatgat
    15541 cgatgttcca atgccgattt cctatctttc caaaaaactg acagaacagt taaaggtgct
    15601 ggaaccattt ggtaaaggga actcgaaacc tttgtttgca cagaaaaatc ttcgggcagt
    15661 ggggattcgt gttttgggca gaaacaggaa tgtggcaaag atgcttctta tagatgaaaa
    15721 tggaataaag atggatgcag tatattttgg agaggcacag gaattcgtgg attttgtaca
    15781 ggcgcatgat accatatctg ttacatatta tcctgaaatt aatgtttttc agggaagaga
    15841 aaacctgcag gtggtcataa agaattattg ttgattttgg cattgaaata agggaaaagt
    15901 atggagtttc gtaaagtttt cgtaaataca ctgtatgata atgcaaattg cacacaaaat
    15961 tgcacataat ttcgacaaat atgatatttt agcataaaat taaacatctg gttcgtcaaa
    16021 ttctacagct aagactgcag ttaagactgc agttaagaca ggagataata caccgattct
    16081 tcaatcattt cgtgattatt cttctggcag caattgtagc aattgtagtt tttgtaaaaa
    16141 aacgtttcgg aggcaaaaag agctgatact tgatcagaaa aaaataagca ataaaaaaat
    16201 ccgtttcagg tgataagcct gagacggatt ttttatgtaa taggaaatta ctccgtaatg
    16261 ttcctattac ataaaaacgc tccgcgagga tgcgaccaga tgcatgagga atatgtctgc
    16321 tgaagcagac cgcatctggc gcgcaaagcg taacaagtcc ctcaaagatt gagggattca
    16381 gggagtttga agcggacttg tccgctttgt tctgtgagga agattccaaa agaaaaaatc
    16441 atccaagtct tctgcggagc atttccggat tcattgcgta gttgatggca gtttcttttg
    16501 tgatgcgtcc atttttgtac aattcaaaaa ggctttgatc catggagcgc atctgtccgg
    16561 gactggaaga aatgacaccg tcgatctgat gaattttatt atcacggatc atattccgga
    16621 tagcgggagt aagacgcata atctcaaaaa caggaatatt tttgccgttg acatccggaa
    16681 ccagttgttg agaaatgaca gcctgaagta ccatggaaag ctgcatgatg atttgatgct
    16741 gctgggatgg ttcaaaaaca tctatgatac ggttgagcga atttgcggct ccgagtgtgt
    16801 gcagactgga aaggatgaga tgaccggttt cggcagctgt catggcagtc tgaatggttt
    16861 cgtgatcacg catttcgcca agaagaatga catccgggct ctggcgaagg gtagcacgca
    16921 gggaagtaat ataattttcc gtatcagtgc atatctcacg ctggcttacg atacaacgat
    16981 cgtgtcgatg caggtattcc agaggatctt ccagcgtaat gatatgccct tcgcgagaat
    17041 ggttgattcg atctataagg caggccatgg ttgtggattt tccgcttccg gcagatccgg
    17101 ttacaagaac catgcctttt gtcagatcag caatactcat gacatcctcg ggaatagaaa
    17161 gctcggcggg atccggcagc tggaaagcga taacacgtat gactgctgcc agagaaccac
    17221 gctgtttgta agcattgata cgaaaacgtg acagacctgg aatagaaaag gaaaagtcat
    17281 cgtcaccggt attgtgcagt cgtgagatat cacggttatt cgccatctga taaattgctt
    17341 cgagaatttc actggtctgt tccggcatca gacggtcacc ataggtggaa agacgtccat
    17401 cggtttttat agaaagtgga cgtcctgcaa taataaaaat atctgaagcg tgcagatctg
    17461 ctgccttaga gagaaattcc agagtttgtt ctttattcat gagtgcctcc tttataaaca
    17521 gactgactgg tgtccggagt ccaggaagcc gtggtgtctg ttttccattg taatatttgt
    17581 atcagagaat ccccggattt ctccgggtat aaaaccttca ggcagacagt gagttgctga
    17641 gtgtcagaga gtgattcggc gaaaagcaat gtctgctttt cctcgtcaaa agtaagctca
    17701 gaatgatcct tgcagaattg tccgacaagg gcaagataat tcttctgatc ggtggcctgc
    17761 cggtaggcat ctgtgagttc tgtctgaatc tcattgataa cagtggaagc ctgactgcag
    17821 gcattataat aatcttctgt ctgttgcatg gaattacggg cggtgcttaa ttctgaacgg
    17881 gaatttccga gtgtcagcaa agaaagcact gcaagacaaa gcacggaaaa gatcagaaac
    17941 agagagggaa ttcccgtggc agtaaaaaag ctgttgtggt ctttcatgag ctggcctcct
    18001 tgtctgaatt ttcaataata ggaaaaacca gatcaatcgt gtaaatctgt atatcatttg
    18061 tggcgtgata gaaagtaagg gttccctgtc tggagtttgc tgtttcgtgt aatgtaagtt
    18121 ccattttata ggaagcctgt gaatcggaac agagttgcca ggaactgtca tagtaccatt
    18181 cgatgagatt gtcctgaatc tgtccatcag gaaacagtga gacaaagctt tttgcggttc
    18241 cgtcactgtc ttccagaatt tcaccgacgg aagttgtgag cgtttgtata tgacgccatt
    18301 cctgagcctg tatatgattt ttttttgcag cagcaaagat acggatacag gcagcactgg
    18361 aaagtgccag aaaaagcaga acaaagatca tttccattaa aaagagactt gtttttgaat
    18421 gtgcggatat ttttttcatg atgcctcctt ggaaacggaa ttctgatgga gataaaaagt
    18481 ttctttgttt ccttcagaat cttttaattc aaaagaataa aaaccaggtc tgctttcaga
    18541 gatctgaaag tcagaaagtt gagcaatcgt tgttccggca gatgcattgg cagaagaact
    18601 gtctgaagta aagagttctt tcagattacc ctgatcaaga taaatataag tgatgtaatc
    18661 ctgatcattc agtgtatcac gaaaacaaag ggcagaaaga ttatccagtt tgccggtgaa
    18721 aattccattt actgtgtcat gctgtctgaa cttggttgta agataggaaa cagcagtacc
    18781 gagagtattt tctgcatttg tattttttac agtctgctga taaatgcgtg ctgaaaaaag
    18841 cagcatgagc agaagaaaaa gaacaaaaat gccaaaaagc agaagagaag ccagttcagc
    18901 aactggatgt ctggtgataa gccttttttt catttggcag ccctctttcc atgtccggca
    18961 gtatcggaca gcagaattac acttatataa ggaagtaggt tggaaccgtt tggggtatat
    19021 tcgacaacaa aacgagagcg gtcataagtt atgtggtaat cattcagaat ctggtccaga
    19081 ctttctggat attgaccatt catggcatat gaccggattg cgccattttc aagtgcctgt
    19141 tccagtgcct gttgttcttt gtgaagggtt tcatcggatg caaagctgac actgatgaaa
    19201 aaaatgctgc tgatcagaat gagaaagcat aaaggtagta acagactgaa tctacgtaaa
    19261 aattttttcc tgtggctgtc aaagagttcc atttatagct cacctcacaa tgcaatatca
    19321 gagagaatac ccagaagcgg catcattaca gaaagcagaa cgagaccgac aagcagggac
    19381 aggatgatga caatcgttgg ctcaacgatg gagattgctt ccgaaatcag atcaactgct
    19441 ttttcacgat attttacgga aagctgatta agtgcctcat ctgccgaacc agattgaaaa
    19501 ccaacagaaa tcagtcttcc ctccataccg gtaaaaagtt tggaatctgt cagtgcctga
    19561 taaaacggag tgccttcttc cagtaaatga cctgtttctt ccagtcgctt caaaatcaga
    19621 ggatgtgaaa ccatttcagc agacagctca agacttgtat ctggagtgag accgcttttc
    19681 agcccgagag aaagtccctg tgcaagacgc ccgtaatcgg cagccagtgg gatatcgcga
    19741 aagactggta agtggtaagc tgcgtttctc agataaatgt gtcctttttc gctcagactg
    19801 agaaaaagaa tcagaccaac caagagaact accaatatca ggaaaatacc ggaataattg
    19861 ctgagaatac tcccggcttt cagtaatcca agagaaagcg tattcatttc catacccatc
    19921 tgctgaaaga cctgctgaaa tacaggaagt acctttacaa gaagaacgac aataacgatt
    19981 cccatcattc caagcatgat caggggatag gtaactgcac ttcgaatctg ttcggaaact
    20041 tcctgttcct gttcatagtg cagagtcagg ctgttcagaa tttcgtccag gcatcctgtt
    20101 tcttcaccgg tctttatata agaaacagaa gaatggggaa atcttccgga agtttccatt
    20161 gcctgtgtaa gacttccggt ttcttccatg gaagtgagca gcgcggtgat gatttcacgg
    20221 tctgtatccg tctgactttc atcttgaaga atcgccaagc cttctgttac agaaatgcct
    20281 gaatgaatca gcattccaag ctgtccgaaa aagttactga gctcccgggc tgttaatgtg
    20341 tatttcataa aaaatctcct ttgccattaa cgtgtgaatt gtacagtgta attgctttcg
    20401 tctccaatgt aatcctgaat agcttctttg tcatcgctgt tagaatcaaa ggtaggatcc
    20461 ataagtgtcc aggtatctcc tttaaaggat actgcctgat tgacccagcc tttggagcgt
    20521 atatatacat cgatccaggc atgcttgata tctccggcat aaccaatctg aagtttgcat
    20581 ggaatatcac agcttcggag catggccgtg gtgagcgcgg cataatcaaa acagatgccg
    20641 gtgcctgttt tcagggtttc atcgacatcg ggaagatatc cggtggtcac agtatctgct
    20701 ttttcataat cataagtcag atttgacaca acataatcgt aaatctgctg caatgcatct
    20761 acatcaacgg tgtcctcatc gatcagggag agcgcaagct ggctggcttt gctgtccggt
    20821 gtaaagttta catattgatt tggatagaga aaaggcagaa aatcattttc aagctgtacg
    20881 gtaactgttt cgctgtaaag agctgcatac tggtcaccct gtacctgttg gtaaccggta
    20941 attgtgtaat caccgctgcc ttctgtaaaa gtgacggttg cggattctcc gggtgcaata
    21001 aaataagaat aaagtacacc agaaggagaa atgatctgca aactgcatgt caggtcagaa
    21061 gaatcggact gggcaataaa gtagccctgg ctgatattgg atacatccag tatcataggc
    21121 gatgagccaa gagtttcttt tccggtggct tcaggaacaa gaacctggag cggggaatag
    21181 acagggggtt catctttctt ttgcgaagaa gatccgcagc ctgaaataaa tattaacaga
    21241 aaaggcagac acaatatcat ggcaaggagt cgtaagcgaa tgaatcggtt catgtgactg
    21301 ctccttgata atatgaaata tttacttgtg tttgttttga attaagtata gcagagtaga
    21361 tgtttacagg caatattcct taagaggttt ttgatttttt gaattattac agaaatgtga
    21421 aatatacagg aaaaaatgtt gacattcact gaaaaaaaaa ctatacttac agcataaagg
    21481 caaacctgct gaaaggcagg gacgcaaagc cacgggtcta aggtcgtgag actaaggcag
    21541 ccggttgccg cattaaattc cgatttagtg acgtattatg gactacagaa gaga
//
