LOCUS       NZ_QSJW01000002        20733 bp    DNA     linear   CON 28-FEB-2024
DEFINITION  Blautia obeum strain AM29-25AC AM29-25AC.Scaf2, whole genome shotgun
            sequence.
ACCESSION   NZ_QSJW01000002
VERSION     NZ_QSJW01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Blautia obeum
  ORGANISM  Blautia obeum
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Blautia.
REFERENCE   1  (bases 1 to 417319)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     A genome reference for cultivated species of the human gut
            microbiota
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 417319)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2018) BGI-CNGB, BGI, No. 11, Beishan IZ., Yantian
            Dist., Shenzhen, Guangdong 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina Hiseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/28/2024 19:09:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,731
            CDSs (total)                      :: 3,671
            Genes (coding)                    :: 3,600
            CDSs (with protein)               :: 3,600
            Genes (RNA)                       :: 60
            rRNAs                             :: 3, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 51
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 10 of 71
            Pseudo Genes (incomplete)         :: 61 of 71
            Pseudo Genes (internal stop)      :: 10 of 71
            Pseudo Genes (multiple problems)  :: 9 of 71
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:03:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 391970
            Orig. end                         :: 412703
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QSJW01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20733
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20733
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20733
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10733](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10733)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     misc_feature    96..111
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.96"
                     /tool="antismash"
     gene            1218..1382
                     /locus_tag="DW767_RS18725"
     CDS             1218..1382
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008703957.1"
                     /locus_tag="DW767_RS18725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_181975991.1"
                     /transl_table=11
                     /translation="MDIDFKEELRKRDELLAGYLKQIEIQEEFIQKQKELIEYLEDHIS
                     KITDIISGV"
     gene            1408..1878
                     /locus_tag="DW767_RS19055"
     CDS             1408..1878
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW767_RS19055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_233435658.1"
                     /transl_table=11
                     /translation="MPDAYDHISLMCRLKAAQTRNKELESGERYIKLKELHQKECRAYE
                     RKIQALLTEIADAHKETIHVRNYWFQVLEDMLQEFEAMQKKADQKLQEMEERALLAERQ
                     RDEALEKAKEFRLKFYETATRLEEEQGKNLKLHAQINRDYENSSIPSSKTIR"
     gene            1978..3081
                     /locus_tag="DW767_RS04525"
                     /old_locus_tag="DW767_04525"
     CDS             1978..3081
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015038.4"
                     /locus_tag="DW767_RS04525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04525"
                     /product="transposase"
                     /protein_id="WP_233435659.1"
                     /transl_table=11
                     /translation="MIFLPPPEEVLDDHAFKKTARTIIKQMVSIRMVMDVKEYHADVYY
                     NSQTGERIHAAFPDGVIDDVNYDGSIRAFLFLLNSDCCTSIDKSRKFLSDLTDGKLNIS
                     KGMISKLSREFALKTEPERRKAYADMLLSPVMHTDCTNGRENGKSCQIYVCATPDGKAL
                     YFAREKKGHEGVKGTVTEDYQGILVHDHDITFYNYGTDHQECLAHVLRYLKDSMDNEPD
                     RTWNKEMRSLVQEMIHFRNGFQPSQEPDPVKVSEFEKRYREILETARMEYGNIPATDYY
                     RDGYNLFLRMEKYMQNHLLFLHDSRVPATNNEAERLLRNYKRKQAQAVTFRSFESIDYL
                     CQCMSMLVLMRLEEPTNIFDRVSRIFG"
     gene            3213..6536
                     /locus_tag="DW767_RS04530"
                     /old_locus_tag="DW767_04530"
     CDS             3213..6536
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016362.4"
                     /locus_tag="DW767_RS04530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04530"
                     /product="restriction endonuclease"
                     /protein_id="WP_117639881.1"
                     /transl_table=11
                     /translation="MNIQQYIHSLTDEEFEQLCTEYLTLHYKNKNITIHGTRLKKDGGK
                     DIVGTAQDVPYEIWAECKRHNRALGLEKISKNVILVISKGINELIYFSTSDITRNAVKH
                     VSIVAAKHNFSVTFIYGNRLYQELSILPRFQYGFEKSNEIIKNDLRISRFFSVFEDTEK
                     YTEESELVLQRDNIFYIDIYLTNLYSATVSDVTCTLPKMADIIFHVPEIHNCFNMLQGS
                     NRVIQIRAEVLSSYTVKHIPALTLKYKCNGHTYSQKVPGGYIDPTKLIYYPLVGENVQN
                     FLSSKILPLLKGNGFSPIYMLNITGKSGTGKTRLLSEIINSAKSYNFQTLYCDAKKQNG
                     FEILREFLCACLGLPYGTGNISCTLDDFSKIIKQYYGNSKVSEAVFSFVFHKKLDPDIL
                     YYLKEALLFFSCNIVGGVSLIWTIDNLQCLDKETLDIIYFLIAHLQKCFPEVIFSLGTN
                     TEIVPLDSQGFVNEFLAKINEYEDVISYVYTCGEMQNNDAKTLYYHAIPNLQGFDYFTR
                     LLLNKSGKRPFDIIMLIHWFYDQNLINISTHNMVIPSKKEEIENFINKVPVKSKEIIDQ
                     RFQLQMHKKFSFDTTLGYFDAFKVVVKSILYFGGETPVDFLASLNIDGDMLFELSQSLF
                     FKYMDKYPKIVFYHDNIYRYFEGYQFYQNDRSLSLKIIKWLNENAWYKSNLRTTAIFDC
                     YIRASEYEEAVRFGISSISSECDKRNFQAVIHIGTELLKDVPKAQDASEELVPNPFAEF
                     MDAGAKFHVYYAVADAYRIYQDLSQSVYYYKKAYKILQQYSISEFTSIDTCRFFHRYSN
                     ACISAADYDDALIVLDYFKKYKGRNNFYDFIMHNRYSVLYLAINDIENALLSIDESLKI
                     AKECKEPQWESVSYSDKAYIYYRAYEDRENTILYFSKAVEKHISEKATINRSSEILAQE
                     AFVDLLTDKLEDAEYLADLALNRALEINGTAMEIKSRNLLGIIQYFSNKAEAAFSTWRK
                     DLVISAQRVNKDGIVKLHTNLGAAYILQSKYVPAKEELEQAYALYQKFKVSLMTHKPLI
                     YNLLFIYNILGDTSKRDKLFEEAYFDNLSSYYNQLISGSENILTDGYWPLQFKHVFFNY
                     "
     gene            complement(6526..7728)
                     /locus_tag="DW767_RS04535"
                     /old_locus_tag="DW767_04535"
     CDS             complement(6526..7728)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012745.4"
                     /locus_tag="DW767_RS04535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04535"
                     /product="glycosyltransferase"
                     /protein_id="WP_147324862.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.4e-21,
                     bitscore: 69.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEERVWPVRNRTCFQNSRKYNKKCTGGKRIMQGLSTIITFYNGL
                     SSLKMCIKLLQDALKAEDIYEIIVVNDNPAMNINFLEDEYSVQVLNMPENKGYAAACNY
                     AVDHARYDTLLFMDCDIYPTGNWLQSMKKTYADILEKGCVSATIYETDSGNLFGYGMGI
                     YEIDILLFLRHGKPSTFSQKDLDVPLVSSGCMMMNRNLYQELGGQDEMCMNIHCDVDLA
                     FRVRKAGYTNRMCANAKVFHRGQISGPIRTVPFRQDVKAYLFKKWGDELYQLCNAENYL
                     KELWMEANYKKISQKSVIVVSFSNSLYRDKYIKLFTQLFDISILQFLDIKNVTGATHII
                     LQENVTWDICRLNIPIVYFADDYRLLLDNYYWFTNRNEEDIIFDKNGNLMYGSDSLETN
                     S"
     gene            complement(7635..8822)
                     /locus_tag="DW767_RS04540"
                     /old_locus_tag="DW767_04540"
     CDS             complement(7635..8822)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0047355 - CDP-glycerol
                     glycerophosphotransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016357.4"
                     /locus_tag="DW767_RS04540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04540"
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="WP_181975992.1"
                     /transl_table=11
                     /translation="MKANRLFIKTKNKKIEYMQDKVLELLFYIFRIFPVQKRKIVVSCF
                     KNHGYCDSPKYIIQQLLKLDCTADIVWLCDFENPPEMPACIRQVPYHSIRGIYEQVTAQ
                     IWISNRRKSRYVRKRKNQYYIQTWHGGVRLKNMERAAINKLSKRYIDSAKNDSKMINLF
                     LSNSDFSTFLIRRDMWYSGKILQKGLPRTDVMLNGDRNTIAKKIKSCLSINEDNKILLY
                     APTFRADMGVTQYTLPSSQILAELENCTGNKWTFVIHMHTNVYNPKYWLGNSEKVINAS
                     SYEDVQELLIAADFLISDYSSIITDFALLNKPILLYCPDLEDYLSDRGFNQDFNALPFP
                     KAYTVSEVINKLPAAVSQKEINTLDWMKKEYGLCETGRASKTVANIIKNVLEGKE"
     gene            complement(9148..9363)
                     /locus_tag="DW767_RS04545"
                     /old_locus_tag="DW767_04545"
     CDS             complement(9148..9363)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW767_RS04545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW767_04545"
                     /product="hypothetical protein"
                     /protein_id="WP_117639887.1"
                     /transl_table=11
                     /translation="MRFVPVKSSGVACSNSGIWRKTGQTGRMYTDYGSGDTGTGTRYLG
                     ARIDDDYYPSNGYTSTGWWNADAVYN"
     gene            complement(9403..9786)
                     /locus_tag="DW767_RS04550"
                     /old_locus_tag="DW767_04550"
     CDS             complement(9403..9786)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW767_RS04550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW767_04550"
                     /product="hypothetical protein"
                     /protein_id="WP_118012144.1"
                     /transl_table=11
                     /translation="MTHKKEVVFSLLFVIMVLCTGCSDKDNGDTSKNNRTSRESFVQEE
                     TIENTDNIDNADGSSAPTPELKTPRTKKELEDALGTVNESGKWTPPAGSHIDPKTGNIL
                     NKDGVVVGTTQEPYSKARPGSQG"
     gene            complement(10001..10480)
                     /locus_tag="DW767_RS19525"
                     /old_locus_tag="DW767_04555"
     CDS             complement(10001..10480)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /locus_tag="DW767_RS19525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04555"
                     /product="accessory gene regulator B family protein"
                     /protein_id="WP_233435660.1"
                     /sec_met_domain="AgrB (E-value: 3.1e-26, bitscore: 86.5,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSPLILAGGVGVGLGSVKHGVALIFPFMVLRKFSGGYHAKNLHT
                     CIFESGFLLFLCIMLSMHVQCDLKLAIATVIASVSLITFSPIDSENRRLDTNEKRTYKK
                     TTVFFVILFGLLDIALFLLGKYIYTICFSVGILLIAGLQAPCIVKKMCTSTKNRL"
     gene            complement(10584..10733)
                     /locus_tag="DW767_RS04560"
                     /old_locus_tag="DW767_04560"
     CDS             complement(10584..10733)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012743272.1"
                     /locus_tag="DW767_RS04560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04560"
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="WP_117639891.1"
                     /sec_met_domain="TIGR04223 (E-value: 3.5e-10, bitscore:
                     34.4, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKRVTKSVAKGMKAALDVVLQTEANTASCAIMYHPKAPKELMKY
                     RRNK"
     gene            10950..11657
                     /locus_tag="DW767_RS04570"
                     /old_locus_tag="DW767_04570"
     CDS             10950..11657
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012743274.1"
                     /locus_tag="DW767_RS04570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04570"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_117639893.1"
                     /transl_table=11
                     /translation="MRILICDDDTLIIEQLQKYIESYFESNHLKCPELVSFTSGESLLA
                     DKNEKDIVFLDIEMPGMNGIYVGNELKKANKNVIIFVVTSYSEYLDEAMRFHVFRYLSK
                     PLDKQRFFRNMKDALAYYNSITTKIPVETKLGVYSFPASQIIAIEAQGRKVIVHTTRQD
                     FDSIHNMDYWLEQLPKNSFFQTHRSFIVNFEHIVDFDHSTIHLSNQQIAAYLTRRKYSS
                     FKNAYLLYLESMR"
     gene            11937..12962
                     /locus_tag="DW767_RS04575"
                     /old_locus_tag="DW767_04575"
     CDS             11937..12962
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025854.4"
                     /locus_tag="DW767_RS04575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04575"
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_330428464.1"
                     /transl_table=11
                     /translation="MGISEIAVLGITSRFFPHFLLETDAELVFYTVFSKIFFFAVIYLL
                     IHLFKGKKSNQEQYDHSELLLMLIPVSSIFIIFTFAAIGETSAFAPPIDFMVTICAVFL
                     LMVNLLVFGINQYNQKKSQEYTDMQLLLQKESDSVEYYEMMLSQNENQSILIHDIKKHL
                     QSIKLLNEKNNSDKINAYIQQLMESSDLKETSKICDNEMLNAILCRYQRQCNEKHIVFH
                     TDIRSGAIQNIYHHDLTSLFCNLLDNAVESADNIPDSFIELTVQKKENSPFIVIILINS
                     CRSTPVYDLDGLPVSHKANNGRHGFGIKSIKKVVKQYHGNLQMYYDNDSGTFHTIITLK
                     Q"
     gene            complement(13245..14234)
                     /locus_tag="DW767_RS04580"
                     /old_locus_tag="DW767_04580"
     CDS             complement(13245..14234)
                     /GO_function="GO:0003953 - NAD+ nucleosidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025056.4"
                     /locus_tag="DW767_RS04580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04580"
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="WP_117639897.1"
                     /transl_table=11
                     /translation="MRIFISHSIKNEKIVLKFAEFLESINSEIEVFCSSERGSIGTGKN
                     FVKTIFDELDACDLFIPVLSREYYESKFCMIELGVAYSYLIKKYESNGEDYIFPYALYP
                     VTKSQALAGTPMMNIQVGEINNKEDIRSLLEYIDLERKIHVGTGANRKLHALITEIDQI
                     LLKNQNIIEMANIGTYFDDKIDFRCKEDIVKYSIKDNAIVVNYNMNPYERENVKYPNFI
                     SMVLGFPDKIDLGRYLDFSDGAEFNFLLTSFTNSLTRIFVEFKHSDGIRPLGTMEFQIN
                     YGENKIHIPLKKMQSKALGQIAEICFVIHPADVLEKEGMFQISEITIS"
     gene            complement(14263..14832)
                     /locus_tag="DW767_RS04585"
                     /old_locus_tag="DW767_04585"
     CDS             complement(14263..14832)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW767_RS04585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW767_04585"
                     /product="hypothetical protein"
                     /protein_id="WP_117639899.1"
                     /transl_table=11
                     /translation="MTHHEAEEYNHLLINEVIKEAETLGIEGKAGGEFIDRNILVIPDD
                     PRKGMIFLGEESASYKLGNVRLNIKSAIIAALELVASVNLPESFFNYLQLLIVTALFIQ
                     KATKQEIKQEDAYVLYFLHQRNCYEQGICESEVQQEYLHWCERTLDKYPDNLEWDKTIE
                     RLREEKIIDIENEKIYLKELVLGHIK"
     gene            complement(14837..15886)
                     /locus_tag="DW767_RS04590"
                     /old_locus_tag="DW767_04590"
     CDS             complement(14837..15886)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW767_RS04590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW767_04590"
                     /product="hypothetical protein"
                     /protein_id="WP_117639901.1"
                     /transl_table=11
                     /translation="MAKKSPEDQNEIPFLEKFMVSQTYDIFRFGGEEIKNDEVGIQRML
                     QNFSGLLTEEQIRENMKKYNLPKMFELVKEYFKKEYDFEGNAIQLNNRYQKTINSYIYN
                     DQKNPTFIHIDELFESTVISFFVAMFKWSKEFDNLDIYGDCFRYTLFLMNDVCIFGEMQ
                     ALDANNALLHLLNGDMQIMKLAEDCYWTIVVFSMAHEIAHAYLAHIGKKYSERHLEKEE
                     YDADAIAYDIVLKIIMKESNEEPILEKYTYLAPAMYMDFFDLYYYTDRVLYKTMLSDSE
                     HPNPVKRKGKLFAIVDRDEYDFDTIDGNHLYGGFLDVYDEYRDQVFLKKEKGKLDKIIH
                     TERRNRMRR"
     gene            complement(16034..16378)
                     /locus_tag="DW767_RS19060"
     CDS             complement(16034..16378)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014427.4"
                     /locus_tag="DW767_RS19060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Ig-like domain-containing protein"
                     /protein_id="WP_233435661.1"
                     /transl_table=11
                     /translation="MKRLRAGIQIIIKVTITLASGKKQVISVTVQKTTVRTTKITGLKS
                     SVTVARNKKLTLKPVISPITSQEKVTYSSSNKKIATVSSSGVITGKKKGTAYITVKSGK
                     IRKKVKVVVK"
     misc_feature    16330..16350
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 24.57"
                     /tool="antismash"
     gene            complement(16540..17265)
                     /locus_tag="DW767_RS04605"
                     /old_locus_tag="DW767_04605"
     CDS             complement(16540..17265)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012307.4"
                     /locus_tag="DW767_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04605"
                     /product="reverse transcriptase domain-containing protein"
                     /protein_id="WP_207659028.1"
                     /transl_table=11
                     /translation="MERQRIFIDDILSNENMNRAYKQVIKNKGAAGIDGMECNDLLSHL
                     KVNGHQLRESIRNQSYKPMPVKRVEIPKDNGSKRKLGIPTVTDRMIQQAAAQVLTPIYE
                     RKFHTNSYGFRPGKSAQQAVLKAAEYMNEGYNWVVDIDLEKFFDTVEHDKMISILNKEI
                     KDGKTLSLIRKFLVSGVMVGEQMEETEIGTPNDAPTAQNHADLRGVVLRNVFRSGGLCA
                     FTGGGTSCGENAGQYVLVL"
     misc_feature    complement(17548..17563)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.08"
                     /tool="antismash"
     gene            complement(17828..18805)
                     /gene="ltrA"
                     /locus_tag="DW767_RS04610"
                     /old_locus_tag="DW767_04610"
     CDS             complement(17828..18805)
                     /EC_number="2.7.7.49"
                     /GO_function="GO:0003964 - RNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0000373 - Group II intron splicing
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ltrA"
                     /inference="COORDINATES: protein motif:HMM:TIGR04416.1"
                     /locus_tag="DW767_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04610"
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="WP_233435662.1"
                     /transl_table=11
                     /translation="MGIPTIRDRIVQQACKIVIEPVFEANFLDSSYGFRPKRDAKQATE
                     KVKKELYKNWYVVDADIQGYFDNINHEILLGLLNRRISDRRVIKLCRQWLQAGVIENGK
                     YYPTEKGSPQGGVISPLLANVYLHVLDSYWENHKELGVIVRYADDAVIVCRTRKDAELA
                     FEHLKRIMTKLKLTLNPQKTKIVDMNKESFDFLGFCYQKFGKTQSGRKLPYMMPSKKAM
                     KKVKDAIRVITCRKSAYEGLEQKVGKLNPLIRGWRNYFQHGNSTKRFKQLDEYVWMKLW
                     RRVYYRRKQKKYRAHVLYGFRKWYATSRIEYFYYLNKKRYVAVF"
     gene            18881..19063
                     /locus_tag="DW767_RS04615"
                     /old_locus_tag="DW767_04615"
     CDS             18881..19063
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573962.1"
                     /locus_tag="DW767_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04615"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_005422953.1"
                     /transl_table=11
                     /translation="MEYMSCPEAAEKWGISERRVQILCKENRIPGVSKIGYMWLIPKSA
                     VKPFDKRIKRSVDNE"
     gene            19056..19754
                     /gene="vanR"
                     /locus_tag="DW767_RS04620"
                     /old_locus_tag="DW767_04620"
     CDS             19056..19754
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="vanR"
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004853366.1"
                     /locus_tag="DW767_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW767_04620"
                     /product="VanR-ABDEGLN family response regulator
                     transcription factor"
                     /protein_id="WP_005422951.1"
                     /transl_table=11
                     /translation="MNEKILVVDDEKEIADLLEVYLKNDNYIVHKYYNGIEALECIQKT
                     EIDLAILDVMLPDIDGFRICQKIRENYYFPVIMLTAKIDDGDKIMGLTIGADDYITKPF
                     NPLEVIARVKTQLRRYQKYNNPTKKQFFPKSEYDIRGLIINKDTHKCFLFGKEISLTPI
                     EFSILWYLCEHQGKVVSTEELFENIWKEKYLDNNNTVMAHIGRLREKLNEPAKNPKFIK
                     TVWGVGYEIE"
     misc_feature    20180..20196
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.88"
                     /tool="antismash"
     misc_feature    complement(20198..20207)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 15.28"
                     /tool="antismash"
     misc_feature    20510..20525
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.69"
                     /tool="antismash"
ORIGIN
        1 tgtcgttagg ggaataattc ttaatcgttt tatctaacat ttcagaaaaa tcgaactgct
       61 cgacactact gaaatacaag tacattgcat tacggattac catatggtca tatggtgcat
      121 cttttttcag atttctgctc agtgtacttt ctacggcttt aaacgctctc ttggtattaa
      181 gctcatcact ttgaagttca tttaactcca gaaaatcatg ccaccagtat ttcgccaccg
      241 tattagaata tattctggct aaaaattcca cagaattcaa atcatcaatc tcaaacaggc
      301 aggttttcca gatctttttt gtgtcctttg aaaagcctga tttaatgctg taatcactat
      361 catcaaagaa atccgtatgc tctaccttcg ccaacagaaa cagcatcttc ccctcatcct
      421 cgatcaaagc caagatcagg cttcctttct gcactctaat atccatactt gcaatctgct
      481 cttgtgcctg tctttccttt cggagcaggc gttctgctat tatatcaatc ctttgcagaa
      541 ctatttcagc ttctgcctgg tgctttatga tctctaatat actgctaatg acctctgtgc
      601 ccgttgattg tgttttatat tcccttacag aaacattccc atttatgtaa gaaatcaact
      661 gttcaatata ttctccaaat tttggcataa tatttcttgc tgaaatttta tcgttttcat
      721 agtcaatcac tctgatggcc tgtgtaatga ttctcataag catatcctct ttatctttcg
      781 cacaaataaa cactgaatct cttgtctgga ttactgtact tctctatttc attatagcct
      841 aagtatacca cacatataaa gcaagcaaaa gaatttaccg ctatctttgc cttggtattc
      901 acaaaaatgt tactgttcag aggtatgtat aagtcattgt aaaaaatgac gaaatttatt
      961 tttttatttt gtggataatc attcgcggca ggaaaaactg tgtttatagt ttttcctgcc
     1021 gctctttttt tgaaaagtta tacaccagat tctggttttg ggaactcatt cttgaagttt
     1081 caggatctac acgaatccct tttttattat aaaacaacta tttatccaca gttagattga
     1141 cgaatgggca ctttctggtg attcgctttt tttctatgtt tctgttatac tttttcttaa
     1201 gaaagagagg ttcccttatg gatattgatt ttaaagaaga acttagaaaa cgtgatgaac
     1261 ttctggccgg ttatcttaaa cagattgaga tccaggagga atttatccag aaacagaaag
     1321 aattgattga atatctggaa gatcatattt caaagattac agacattatc agtggcgttt
     1381 gattataact gtactggagg aaaacatatg cctgatgcgt atgatcacat ctcacttatg
     1441 tgtcggctga aagccgcaca gacaagaaat aaagaactgg aatccggtga acgctatatt
     1501 aagctgaaag aactccatca aaaggaatgc agagcctatg aacgtaagat ccaggcgttg
     1561 ctaacggaga tagcggatgc acataaagaa accatccatg tccgcaatta ctggtttcag
     1621 gtactggagg atatgctcca ggagtttgag gcaatgcaga aaaaagctga ccagaagctc
     1681 caggagatgg aggaacgtgc ccttcttgct gagagacaaa gagatgaagc attggagaaa
     1741 gcaaaagaat tccgccttaa gttttatgaa accgccaccc ggctggaaga agaacaggga
     1801 aagaatctga aacttcatgc acagatcaac cgtgattatg aaaactcctc tattccttct
     1861 tccaaaacca tccggtagaa aaagattgca aacagcaggg aaaagacagg caggaaaccc
     1921 ggagggcagc cgggacataa aggacatggc cgaaaaaagc aggagcctac acagccggtg
     1981 atttttcttc caccaccgga agaagtgctt gatgaccatg cctttaagaa aacagcaaga
     2041 acaattataa aacaaatggt aagcatccga atggtcatgg atgtaaaaga ataccatgct
     2101 gatgtttatt ataacagcca gacaggggaa cgcatacatg ctgcatttcc ggatggcgtt
     2161 attgatgatg tgaattatga tggcagcatc cgggcatttc tgttccttct gaatagcgac
     2221 tgctgtacct ctattgataa gagcagaaag ttcctgtctg atctgacaga tggaaaacta
     2281 aacatttcca aaggcatgat aagtaaactc agcagggagt ttgctttaaa aacagagcct
     2341 gagcgcagga aagcctatgc agacatgctg ctttcccctg tcatgcatac agactgtaca
     2401 aacggcaggg aaaacgggaa aagctgtcag atttatgtct gtgcaacccc ggatggaaaa
     2461 gcattgtact ttgcccgtga gaaaaaagga cacgagggag taaagggcac tgttacagaa
     2521 gattaccagg gaatccttgt ccatgaccat gatattacct tttataatta tggaacggat
     2581 caccaggaat gtcttgccca tgtgctgcgt tacctgaaag acagcatgga taatgaacca
     2641 gaccgcacct ggaacaaaga gatgcgttca ctggtacagg agatgatcca tttccgaaat
     2701 ggattccagc catctcagga accggatccg gtaaaggtat ctgagttcga aaaaagatac
     2761 cgtgagatac tggaaacagc caggatggaa tatggaaaca ttccggcaac cgattattac
     2821 agggacgggt ataatttatt cctgagaatg gagaaatata tgcagaatca tctgctgttc
     2881 ctgcatgatt cccgggtacc tgccactaat aatgaagccg aaagacttct gagaaactat
     2941 aagcggaaac aggcgcaggc tgtgacattt aggagtttcg aaagtatcga ttatctctgc
     3001 caatgcatga gcatgcttgt tttgatgcgc ctggaagaac caacgaatat atttgacaga
     3061 gtatccagga tatttggata agaaaaccga tggatttgac tgttatcagt ttataccatc
     3121 ggttttctca tgtccagcta acctctgaac agtaacacaa aaataataga taattagcag
     3181 ttatccatta tttcctatgg agatgaatac aaatgaacat ccagcaatat atacacagcc
     3241 ttacagacga ggagtttgaa cagctttgca cggaatacct gaccttgcat tataaaaata
     3301 aaaatattac catacacggt acgcgtttga aaaaagatgg cggaaaagac attgtaggaa
     3361 ctgcacagga tgtcccctat gaaatatggg ctgaatgcaa gaggcacaac cgtgcccttg
     3421 gccttgagaa aatatctaaa aatgttattt tggttatttc aaaaggaatt aatgagctga
     3481 tttatttctc tacaagtgat attaccagaa atgcggttaa acatgtttcc atagttgctg
     3541 ccaagcataa tttttctgtc accttcatat atgggaaccg tctgtatcag gaattatcaa
     3601 ttcttccacg ttttcaatat ggttttgaaa aatcaaatga aataataaaa aatgatttaa
     3661 gaatatctcg tttttttagt gtatttgaag atacggaaaa atatacagaa gaatcggaac
     3721 tcgtattgca acgagataat attttttaca ttgatattta tctgactaat ttgtatagtg
     3781 caactgtttc agatgtaacc tgcacattac cgaaaatggc agatattata tttcatgttc
     3841 ctgaaatcca caattgtttt aatatgctgc agggaagtaa ccgtgttata caaatacgcg
     3901 ctgaagtatt aagctcttac accgtgaagc atatacccgc gcttacttta aaatataagt
     3961 gcaatggtca tacatattcc caaaaagttc ccggaggata tatagatcca acaaaactca
     4021 tctactatcc attggtagga gagaatgtac agaatttctt aagcagtaaa attcttccgc
     4081 ttctgaaggg caacggattc agcccaattt atatgcttaa tataactggg aaatcaggaa
     4141 caggaaaaac acggctattg tctgaaataa taaattctgc taaaagttat aattttcaga
     4201 cgttatattg cgatgcaaaa aaacaaaacg gatttgaaat tttaagagaa tttttatgtg
     4261 cttgtctggg gttaccttat ggcactggaa atatcagctg cacattagat gatttttcta
     4321 aaataatcaa gcaatattat gggaactcaa aagtaagtga ggcagttttt tcttttgtat
     4381 ttcataagaa attagatcct gatatcttat attatctgaa agaggcactt cttttcttct
     4441 cttgtaatat agtaggcgga gtttctttaa tttggacaat agacaattta caatgtctgg
     4501 ataaagaaac tctggatatc atatatttcc tgattgcaca tttacagaaa tgttttcctg
     4561 aagtgatttt ttctttaggc acaaatacag aaattgtgcc tcttgactct cagggatttg
     4621 taaatgaatt tttggctaaa ataaacgaat acgaagacgt gatttcgtat gtgtatactt
     4681 gcggtgaaat gcagaacaat gatgcgaaaa cattgtatta tcacgctatt cccaatttgc
     4741 aagggtttga ttattttacg cgcctgctat taaacaaaag cggaaaacga ccatttgata
     4801 ttattatgct gattcactgg ttttatgacc agaatttaat taatatatca acacataata
     4861 tggtgattcc ttcaaaaaaa gaagaaattg aaaactttat aaataaagta cctgtaaaaa
     4921 gcaaggaaat tatcgatcaa cgcttccaac tgcaaatgca taaaaaattc tcttttgata
     4981 ccacattggg atatttcgat gcatttaaag ttgttgtgaa gtcaatattg tattttggag
     5041 gagaaacacc tgttgatttt ttggctagtt taaatataga cggtgatatg ttatttgaat
     5101 taagtcaatc tttatttttt aagtacatgg ataaataccc taaaattgta ttttaccatg
     5161 acaatattta cagatatttt gaagggtacc aattttatca gaatgaccgc tcgctttctc
     5221 tgaaaattat taagtggcta aatgaaaatg cctggtacaa atccaacctt aggacaacag
     5281 caatttttga ctgttatata cgcgcttccg aatatgaaga agctgtcagg tttggaatat
     5341 cttctatctc aagcgaatgt gacaaaagaa attttcaggc agtcatacat attggcacag
     5401 agctattaaa agatgttccg aaagctcagg atgcttccga agaattagtg cctaacccct
     5461 ttgcagaatt tatggatgca ggtgcaaaat ttcatgtcta ctatgcagtg gcagacgcat
     5521 acagaattta tcaggatttg tctcaaagcg tatattatta taagaaagcc tataaaatat
     5581 tgcagcaata cagtatttcg gaatttacgt ccattgatac atgccgtttc tttcacaggt
     5641 actcaaatgc ctgtatttca gcagcggatt atgacgatgc attaatcgtc ttagattatt
     5701 tcaagaagta taaaggacgg aataactttt atgatttcat tatgcacaat cggtattctg
     5761 tcttatattt agcaataaat gatatagaaa acgcattatt gtcaattgat gaatcattaa
     5821 aaatagcgaa agaatgtaaa gaaccacagt gggaaagtgt ctcttattca gataaagctt
     5881 atatttatta tcgtgcctat gaagataggg aaaatacaat tctatatttt agcaaagcgg
     5941 tagaaaaaca catttctgaa aaagcgacca tcaatcgaag ttctgaaatt cttgcgcagg
     6001 aagcttttgt ggatttacta acagataagc tggaggatgc tgagtatctg gcagatttgg
     6061 cactgaaccg tgcacttgaa attaatggaa cagcaatgga aataaaaagc agaaatttat
     6121 taggaattat tcaatatttc agtaataaag ctgaagctgc attttccaca tggcgaaagg
     6181 atcttgtaat ttccgctcaa agggtgaata aagatggaat agtaaagctg catacaaatt
     6241 taggcgctgc ctacattctg caaagtaaat atgtgccagc taaggaagaa cttgaacagg
     6301 catatgctct ttatcaaaaa ttcaaggtct ccttgatgac acacaagccg ctaatctaca
     6361 atttgctatt catttataat attttggggg atacatcaaa aagagataag ctgtttgaag
     6421 aggcttattt cgataatctc tcttcttact acaaccagct tatctctggg agcgaaaaca
     6481 tcctgacaga cggctattgg cctttacagt ttaaacatgt attctttaac tattagtttc
     6541 cagggaatct gatccgtaca tcaggttccc gtttttatca aaaataatat cctcttcatt
     6601 acgatttgta aaccaatagt agttatccag caataatctg taatcatctg caaaatatac
     6661 aataggaata tttaatcggc atatatccca ggttacattt tcctgcaaaa taatgtgtgt
     6721 ggcgccggta acatttttta tatctaaaaa ttgcaaaatg gaaatgtcaa acaattgtgt
     6781 gaacagcttt atgtatttat cacggtataa cgaattacta aaacttacaa caatgacact
     6841 tttttgcgat atttttttat aatttgcttc catccagagc tcttttaaat agttttcagc
     6901 attgcataat tgatataatt catcgcccca ttttttgaat aaatatgctt ttacatcttg
     6961 tctaaaaggt actgtccgaa taggtcctga aatctgtcca cggtgaaaaa ctttggcgtt
     7021 tgcgcacatt ctgtttgtat agccagcttt tcgaacacga aaggccaggt ctacatcgca
     7081 atgaatgttc atgcacattt catcctgtcc gccaagttcc tggtataaat tacgattcat
     7141 catcatgcag ccagaagaca caagcggaac atcaaggtct ttttgggaga atgtagaagg
     7201 ttttccatgg cgaagaaaca acagaatatc aatttcataa attcccatac cgtatccaaa
     7261 taagtttccg gaatctgttt cataaattgt cgcggataca catccctttt ccaaaatatc
     7321 tgcatatgtt tttttcatgc tttgcaacca attacctgtt ggatagatat cacaatccat
     7381 aaacaacaat gtatcatacc gtgcgtgatc aacagcataa ttacaggctg ctgcataccc
     7441 tttattttcc ggcatattta atacctggac agaatattca tcctctaaaa agttaatatt
     7501 catggctgga ttgtcattga cgacaataat ttcatatata tcttctgctt ttaatgcatc
     7561 ctgcagcagc ttgatacaca tttttaagga agacaatcca ttataaaaag ttatgattgt
     7621 tgaaagcccc tgcattattc ttttccctcc agtacatttt ttattatatt tgcgactgtt
     7681 ttggaagcac gtccggtttc gcacaggcca tactctttct tcatccaatc caatgtattt
     7741 atttcttttt gcgatacagc tgctggaagt ttatttataa cttcagaaac tgtatatgct
     7801 tttggaaaag gcaaagcatt aaaatcctga ttaaatcctc tgtccgaaag ataatcctct
     7861 aaatctggac aatatagcag tataggttta tttaataatg cgaaatctgt aataatactg
     7921 gaataatcac tgattaaaaa atcagctgct ataagtaatt cctgtacatc ttcataagat
     7981 gaagcattta ttactttttc tgaattcccc agccagtatt tggggttata aacatttgta
     8041 tgcatatgaa tgacaaatgt ccacttattg cctgtacagt tttccagttc tgccaatatt
     8101 tgactggatg gcagtgtgta ttgggtaact cccatatctg ctcgaaaagt aggcgcatat
     8161 aataatattt tgttgtcttc attaattgat agacaagatt ttattttttt agctatagta
     8221 ttacgatctc cgtttaacat tacatccgtt cgcggaagcc ctttttgcag tatctttcct
     8281 gaataccaca tatctcttct tataagaaag gtagaaaagt cactattaga caagaataaa
     8341 tttatcattt tagaatcatt ttttgcacta tcaatatatc tcttggacaa cttatttatt
     8401 gctgcacgtt ccatattttt cagtcgaaca ccaccatgcc atgtctggat ataatattga
     8461 ttttttcgtt ttcgaacata tcgtgacttg cggcgattag aaatccatat ttgagctgtt
     8521 acctgttcgt atattccccg gatcgaatga tatgggactt gacgtatgca agctggcatt
     8581 tcaggtggat tttcaaaatc gcatagccag actatgtctg ccgtgcaatc taattttaac
     8641 agttgttgaa taatatattt ggggctatca caataaccgt gatttttgaa acatgaaaca
     8701 acaattttcc ttttctgaac aggaaatatt ctgaaaatat aaaatagtaa ttctaaaacc
     8761 ttatcctgca tatactctat ctttttattt ttggttttta taaataggcg atttgccttc
     8821 atgtatatca ttcctctgaa aaagaatatc cttaatacaa ttagagataa tggataactg
     8881 ctaattatct gctattcatt ataccagata ttcccaagtt tttccatact aagaaataca
     8941 caatgtcatg atgttggggt cgaaacataa cgtttcgacc ccaacatcat aaaatactct
     9001 gtagcgcctt aatttcagct tttatttagt ttaacctgaa cttttcatcc gagttacact
     9061 agagtggttt cagggcacat attccccaga aatacagcag ttgtttaggt tatgatattt
     9121 agtgtaactt ttttgcaaaa ttgagcttta attataaacc gcatctgcat tccaccatcc
     9181 agtagatgta taaccattac tcggataata atcgtcatca attcttgcac ctaaatacct
     9241 agtacctgta ccagtgtctc cagatccata atcagtatac attcttcctg tctgaccagt
     9301 ttttctccat ataccactat tggaacaggc aaccccactg ctcttcactg gcacaaagcg
     9361 cattccataa ggactgcttc ctgttttttt tacaccatat catcatcctt gagaacctgg
     9421 acgcgcttta ctatatggtt cctgcgtagt tccaaccacg accccatctt tattcagtat
     9481 attacctgtt ttggggtcta tatgagaacc ggctggtggc gtccattttc ccgactcatt
     9541 cactgtacca agcgcatctt ccaattcctt tttcgttcgg ggcgttttca gttctggcgt
     9601 tggtgccgag ctgccgtctg cattgtctat attgtcagta ttctcaatag tttcttcttg
     9661 aacaaatgat tctcttgaag tcctgttatt tttagacgta tctccattat ctttatcact
     9721 gcagcctgta cataacacca ttattacaaa caacaagcta aaaacaactt ctttcttatg
     9781 tgtcatttta atcttttacc tccattatgt ccgtttaact actccgaacc gaactactca
     9841 atttaaagcg atagaattct atcattgtcc cattggaatc cactcccttt caatgaacaa
     9901 actgaattaa ctgtaaatca agaactttga tcaaatcaat gacaaacttt attatcttta
     9961 tttttgccat gatttcaacc ccttttgcac caaacgacat ttacagtctg tttttggtcg
    10021 atgtacacat tttctttacg atacaaggtg cttgtaagcc tgctatcagt aatatcccaa
    10081 cagaaaaaca gattgtatag atgtactttc ccagcaagaa taaagctata tctaacagcc
    10141 caaacaatat cacgaagaac actgttgttt ttttatatgt ccttttctcg ttagtatcaa
    10201 gtcttctgtt ttcactgtct attggactaa atgtaatcag gctcacagac gcaataactg
    10261 tagctattgc caacttcaaa tcacattgca catgcattga taacattatg cacagaaaca
    10321 atagaaaacc agattcaaaa atacaagtgt gcaaattttt tgcatgataa ccaccactaa
    10381 attttctcag aaccataaac ggaaaaataa gtgcaactcc gtgttttaca cttcctaagc
    10441 caacgccaac acctcctgca aggataagtg gtgataccaa tagaaaaaac tatataatgc
    10501 atacttgtaa agttccttat ccgcctcgtt tatcgcatta caccggatca tccaatcaac
    10561 tactgtatct gtacattttt ctattacttg tttctcctgt atttcattaa ttctttcggt
    10621 gcttttggat gatacataat cgcacatgaa gctgtgttgg cttcagtctg taacacaaca
    10681 tctaatgctg ctttcatccc ttttgcaacc gatttagtta cccgtttctt cataatgtcc
    10741 tctctccttt cctaaagatt gtcattgatt ttcacataaa caatcatatg ccggagactt
    10801 tatcgaactg cttgtaaaac gaaataacaa agcacataat gaaccaaaat tgtaattaat
    10861 atgtcttttc atacgcattt tttgcatttg gaaattctat atgataagat gtatgtaaat
    10921 atactttcat tagaaagcca ggtgcaaaaa tgcgtatttt aatttgtgat gacgatactc
    10981 tgataattga acaattacag aaatatattg aatcctactt tgagtcaaat catttaaaat
    11041 gtcccgagtt agtttccttt accagtggcg aatctttatt ggctgataaa aacgaaaaag
    11101 atattgtttt tctggatatt gaaatgcccg gtatgaatgg aatttatgta ggaaatgaat
    11161 taaaaaaagc aaataaaaat gtcataattt ttgttgtcac ctcttactcc gaatatttgg
    11221 atgaagcaat gcgttttcat gtattccgct atctttccaa acctttggac aagcagcgtt
    11281 ttttccgaaa tatgaaagac gccctagcat attacaattc cattactacc aaaattcctg
    11341 ttgaaactaa gctgggagta tattcatttc ctgcttcaca gattattgca atagaagcac
    11401 agggacgaaa agtaattgta catactaccc ggcaggattt tgattccatt cataatatgg
    11461 attattggct ggaacaactc cccaaaaaca gttttttcca gacacacagg agctttattg
    11521 ttaatttcga acatattgtg gactttgatc attccaccat acatttatcg aatcagcaga
    11581 ttgcagctta tctgacacgc agaaaataca gttcctttaa aaatgcttat ctactatatc
    11641 tggaaagtat gaggtaaaaa taaatgggac atatcgtttt acttcttttt agctttttta
    11701 cagaagcagt tatactatgg caatacgcat ccagcctttt tacctcttct tatagcagta
    11761 aaataaggct ggcactattg agtgctcttt atacaatatt gtttcttctt tccctgctcg
    11821 aacaaacagg actaaacgtt gtcagctttt ttgtgtttaa cactgttttt ctttatatgt
    11881 tgtttaaact caagttgtta ttggcactct tccattcggc tatccttaca gcaattatgg
    11941 gtatatctga aattgcagtt ctggggatta catcaagatt ttttccgcat tttctcttag
    12001 aaacagatgc cgaacttgtt ttttatacgg tttttagcaa aattttcttt tttgcagtca
    12061 tctatttatt aattcatctg ttcaaaggaa aaaaatcaaa tcaggaacag tacgatcact
    12121 ccgaacttct tttaatgtta attccggttt cgtctatttt tataattttt acttttgcag
    12181 caataggtga aacatcagcc tttgcaccgc ctattgattt tatggtaaca atctgtgctg
    12241 tttttctgct gatggtcaat ctgcttgtat tcggcatcaa ccaatataat cagaaaaaat
    12301 cacaggaata tactgatatg cagttgcttc ttcagaaaga atcggattcc gttgaatact
    12361 atgaaatgat gctttcacaa aatgaaaacc agagcattct gattcacgat ataaaaaaac
    12421 atctacaatc tatcaaatta ctcaatgaaa aaaataattc tgataaaata aatgcttata
    12481 tacaacagct tatggaatct tctgatctaa aagaaacctc aaaaatctgc gataatgaaa
    12541 tgctgaatgc aattctctgc cgctatcagc ggcaatgcaa cgagaaacac attgtttttc
    12601 atactgatat cagaagcggt gccattcaaa acatttatca ccatgattta acatcgttat
    12661 tctgcaactt attggataat gcagtggaat cagcagataa tatccctgat tctttcattg
    12721 aacttacagt acaaaaaaaa gaaaattcac cttttatcgt tatcatactc ataaattcct
    12781 gcagaagtac ccctgtgtac gatctggatg gacttcctgt atcccataaa gcaaacaatg
    12841 gcagacatgg cttcggaatt aagagtatta aaaaagtcgt aaaacaatat cacggaaatt
    12901 tgcaaatgta ttatgataat gattccggta ctttccatac aatcataact ttgaaacagt
    12961 aatattaaac cattttccaa atgcaaacat tcttttaaaa atgccacttt taagaaccat
    13021 atttccaagg gaaaaggctg tattgtggaa agttacagtg taagagcctg cacaaagtgc
    13081 gttgcaattc agaataaggc attgctaagt tctacacttt atcccaagtg tccacataat
    13141 tgacatgtaa caagcctcaa aatcggatag ctgataacag tctattgcga ttttgaggct
    13201 tgttgattat taaaattatt tactataaaa tactcgatac aatgctagct tattgtgatt
    13261 tcactaattt ggaacattcc ctctttttct aacacatctg ccggatgaat tacaaaacaa
    13321 atttctgcta tttgtcctaa tgccttggat tgcattttct ttaaaggtat atgtattttg
    13381 ttttctccat aatttatttg aaattccata gttcccaaag gtctgattcc atcagaatgc
    13441 ttgaattcta caaaaattct agttaatgaa tttgtaaaac ttgtcagtaa aaaattgaat
    13501 tcagccccat cgctgaaatc cagatatctg cctaaatcta ttttatctgg gaaacctaat
    13561 accatgctaa taaagttagg atattttaca ttttcccttt catatggatt catattataa
    13621 ttaactacaa ttgcattatc cttaatacta tatttaacaa tatcttcttt acatcgaaaa
    13681 tcaatcttat catcaaaata tgttccaatg tttgccattt cgataatatt ttgatttttt
    13741 aataaaattt gatctatctc tgttataaga gcatgtaatt ttcgatttgc tcccgtaccg
    13801 acatgaattt ttcgttccag gtctatatat tcaagaagtg atctgatatc ctctttgtta
    13861 ttaatttctc ctacctgaat attcatcatt ggtgttcccg ccaatgcctg acttttggtt
    13921 accggataca acgcatacgg aaaaatgtaa tcttccccat tgctttcata cttttttatc
    13981 aaataagaat atgcaacccc caattcaatc atgcaaaatt tgctctcgta atactctctg
    14041 ctcaagactg gaataaaaag gtcacaggca tctaattcgt caaatattgt ttttacaaag
    14101 ttttttccag ttccaatgct tcccctttca gaagagcaaa acacttcaat ttcactatta
    14161 attgattcta aaaattctgc aaattttaaa acaatttttt cgttttttat tgaatgacta
    14221 ataaaaatac gcatatctta atttcctttc tttcaaataa agttacttga tatgtcctaa
    14281 taccagctct ttcaaataga ttttttcatt ttcaatatct ataatttttt cttcacgtaa
    14341 cctttcaatg gttttatccc attctaaatt atccggatat ttatccagag tcctctcgca
    14401 ccaatgcaga tattcctgtt gaacctctga ttcacaaatt ccctgttcgt aacagttccg
    14461 ttggtgtaga aaatataata cataagcatc ttcctgtttg atttcctgct ttgtagcttt
    14521 ttgaataaac aaagctgtga cgattaataa ttgcaggtaa ttaaaaaaac tctctggtaa
    14581 attgactgat gcaactagtt ccaatgctgc tataattgca cttttaatat ttagacgcac
    14641 atttcctaat ttgtacgatg cggattcttc tcccagaaaa atcattccct ttctgggatc
    14701 atcaggaatt accaagatat ttctatcaat aaattcacct ccagctttcc cttcaatccc
    14761 aagtgtttct gcttctttta ttacttcatt gattaataaa tgattatact cttctgcttc
    14821 atggtgggtc atttactcat ctcctcattc tgtttcttcg ctctgtatga ataattttat
    14881 ccaattttcc tttttctttt tttagaaaaa cctgatccct atattcatca tagacgtcaa
    14941 ggaatccacc atatagatga tttccatcta tcgtatcaaa atcatattca tctctatcta
    15001 caatggcaaa taactttcct tttcgcttaa ctgggtttgg atgctctgag tctgaaagca
    15061 ttgtcttata caatacacgg tctgtataat aatacaagtc aaaaaaatcc atatacattg
    15121 caggtgccaa ataagtatat ttttccagaa tcggctcctc attactctcc ttcatgataa
    15181 ttttaaggac aatatcatag gctattgcat ctgcatcgta ttcttccttc tccagatgtc
    15241 tttcggagta ttttttgcca atatgcgcga gataagcatg tgcaatttcg tgagccatgc
    15301 tgaaaactac aatcgtccaa taacagtctt ctgcaagttt cataatctgc atatctccat
    15361 ttagtaaatg cagcaaagca ttatttgcat caagtgcctg catctcgcca aaaatacata
    15421 catcattcat caaaaaaagt gtgtatctaa aacagtctcc gtaaatatcc aagttatcaa
    15481 attctttgga ccacttgaac attgctacaa aaaaagaaat cactgttgat tcaaataatt
    15541 catctatatg aataaaagtt ggattttttt gatcgttata aatatagcta ttgattgtct
    15601 tctgataacg attatttaac tgaattgcat ttccttcaaa atcatattct tttttaaaat
    15661 actcttttac taattcaaac attttaggga gattatattt tttcatattc tcccgaattt
    15721 gttcttctgt taaaagtcct gagaaatttt gcagcattct ttgtatgcca acttcatcat
    15781 tttttatttc ttcacctccg aagcgaaata tatcatacgt ttgtgacacc ataaactttt
    15841 ctaaaaaggg gatttcgttc tgatcttcag gtgatttttt tgccatattt atcatctccc
    15901 attatttttt ctatatttta ccatattttt attattgcca ctatatttta atataaatat
    15961 tatataattt caaaaaatag gagttgccat tcaatgtgca ttcatagaaa ggcagctcct
    16021 gcttgaatca tttttattta acaactactt ttactttttt gcggatcttt ccagatttca
    16081 ctgtgatata ggctgttccc tttttctttc cagtgatcac accactggaa cttaccgttg
    16141 cgatcttctt atttgaagaa ctgtaggtga ctttctcctg ggaagtgatc gggctgatga
    16201 ccggtttcag cgtaagtttt ttatttcttg caacggtcac gcttgatttc agtccggtga
    16261 tctttgttgt tcttaccgtt gttttttgca cagtaacgga aatgacctgt ttcttgccgc
    16321 tggccagtgt aatggtcact ttgattatta tttgaattcc agccctcagc cttttcattg
    16381 acagatggct aatttgggct taacaattat tgagcatccc ttaactgatc tacaatgctg
    16441 catttcgctg cgttatcata catcatgcaa ggaatcagcc acccaagtag aagaaatacc
    16501 ggaattgtca gcaggacagg cagaacggtg aaccgatact caaagaacca gaacatactg
    16561 cccagcattt tccccgcaag aggtcccacc gccagtgaaa gcacaaaggc cgccgctacg
    16621 gaagacattg cgtaaaacaa cccctcgtag atcagcatgg ttttgagctg tcggggcgtc
    16681 attcggggtt ccaatctctg tttcttccat ttgttctccg accatgactc cacttaccag
    16741 aaattttcgg attagcgaaa gtgttttccc atccttgatt tctttgttca gaatagatat
    16801 catcttatca tgttctactg tatcaaagaa cttttccaga tcaatatcaa cgacccagtt
    16861 atatccctca ttcatgtatt cagctgcttt taacactgcc tgttgtgcac tctttccggg
    16921 tctgaatcca taactatttg tatgaaattt ccgttcatat ataggtgtta atacctgtgc
    16981 agccgcctgt tgaatcatgc ggtctgtaac tgtaggtatt ccaagttttc gtttacttcc
    17041 attatcttta ggaatctcca ccctttttac tggcattggt ttatatgact gatttcttat
    17101 actctctctg agttgatgac catttacttt caaatgggaa agcaggtcat tacattccat
    17161 tccatctatc cctgccgcac ccttattctt tattacttgt ttataagcac ggttcatatt
    17221 ttcatttgac agaatgtcat ctataaatat tctttgtctc tccatgcgtt gtttcctttc
    17281 cctttcgtga gcttcaacca catagtactt gtggtacccc tctcggcatg tgtattgtca
    17341 aaaactctca attgggactt actccaactg attaactgtt ccgtccttcg ctccatcccc
    17401 attacagaga cttcttcact actatgacgt ctgctgactt cctatgattc gttgttacta
    17461 tggctaatga taccacccat aggatctccc acggttaaaa acgtcatctt tcccatcatc
    17521 tatccgccat gtctactacc agtcctttgt tagctatcgg acttcaacct gttcagcggt
    17581 cttatccaga ctgtaagcct tatacatgat ttctgttcgt cggaccaatg gtttgcctca
    17641 ggcttccttc agattccact ttacagtgga cacccttgcc atattgacta tgcgcttccc
    17701 gctaacgggt acgcttaggt agggtcaagc gatggcgcgg taacttccgt ttccatcacc
    17761 tgccacttca aaccgtgcat gaggttctcc ctcacacggc tttccgataa tcttcttccc
    17821 acagcattca aaagactgcc acatatcttt tcttatttag ataatagaag tactctattc
    17881 tactagttgc ataccacttt cgaaatccat acagcacatg tgccctgtat ttcttctgtt
    17941 ttcgtctgta atacacccgt ctccagagtt tcatccacac gtattcatca agctgtttaa
    18001 atcgttttgt tgagtttcca tgctgaaagt agtttctcca tcctcttatg agcggattta
    18061 atttccccac tttttgttcc agcccctcat aagctgattt tctgcaagta attactctga
    18121 ttgcatcctt tacctttttc atcgcctttt tactaggcat catataaggc agcttccgtc
    18181 cactttgagt tttaccaaac ttctggtaac agaatccaag aaagtcaaag ctctccttat
    18241 tcatatctac aatctttgtt ttctgcggat tcaacgtcag tttcaactta gtcattattc
    18301 ttttcagatg ctcaaacgct aattctgcat cttttcttgt tctacacact atcactgcat
    18361 catctgcata tctgactatg acgcccagtt ccttatgatt ttcccagtag gagtccaata
    18421 catgaagata gacatttgct aacaacggac taatgactcc tccttgcggt gaaccttttt
    18481 ccgttggata atatttccca ttttcaatga ctcctgcttg taaccactgt ctgcataact
    18541 taatgaccct tctatcactg atgcgacgat ttaataatcc cagtagtatt tcatgattga
    18601 tgttgtcgaa gtatccctgt atgtctgcat ctactacata ccagttttta tacaattctt
    18661 ttttcacttt ttctgtagcc tgttttgcat ctcttttagg gcgaaatcca taagaactat
    18721 ctagaaagtt tgcttcaaag acaggttcta tcactatctt acaggcttgt tgcacaatcc
    18781 tgtctctaat agtcggtatt cccaatatca tgtacttgct attattcggt tatccgagta
    18841 taattatatt gataatgttt gaagaaagga cggttacgat atggaatata tgtcttgtcc
    18901 cgaagcagcg gaaaaatggg gtatttctga acggcgtgtg cagatacttt gtaaagaaaa
    18961 tcgaatacct ggtgtttcaa aaatcggtta tatgtggttg atacccaaga gcgcagtaaa
    19021 accatttgat aaaaggataa aaaggagtgt agacaatgaa tgaaaaaatt ttagttgtag
    19081 atgatgaaaa agagatagca gatttacttg aagtttatct taaaaacgat aattatatag
    19141 tacacaaata ttacaatgga attgaagcat tggaatgtat tcagaaaacg gaaattgatt
    19201 tggcgatatt ggacgttatg cttcctgata tagacggatt ccgtatttgc caaaaaatta
    19261 gagaaaatta ttatttccct gttattatgc ttacagctaa aattgatgat ggcgataaaa
    19321 taatggggct aacaataggt gccgatgatt atataacaaa accttttaat ccccttgaag
    19381 tcattgcaag agtgaaaaca cagttaagac gctatcagaa gtacaacaat ccaacaaaaa
    19441 agcagttttt tccaaaaagt gaatatgaca ttagaggatt gattatcaat aaggacacgc
    19501 ataaatgctt tttgttcgga aaagaaatat ctttaactcc tatcgagttt tcaatccttt
    19561 ggtatttatg tgaacatcaa ggcaaagttg tttcaactga ggaactattt gaaaatatct
    19621 ggaaagaaaa atatttagat aataacaaca ccgtaatggc acatataggg cggcttagag
    19681 aaaaattaaa tgaacccgcc aaaaatccaa aatttatcaa aacagtttgg ggggtaggtt
    19741 atgaaattga ataaaaatga acaaaattat ctgcttacaa tcctgtttaa aagttatatc
    19801 ttacagagtg taatttgttc gggaattatc ttagtgtgta cggtttcgtt agatatggga
    19861 cttacttggg tactggatag atatgtggaa cattactacc tgatatatag gggactttat
    19921 gtttatatgg tagggcttat attatgggta gtttgcattt tgtatttgac ttataaactt
    19981 ttgaaaaagg ttgttaatta tgtctacgag ttacaagctg caacaggaaa actatttgat
    20041 aaatcagtag attatattga actctcaccg gaactaagcg aaattgctat caacataaat
    20101 cgcttaaagc aagaagcaga aaacaatgcg cgacttgcac aggaaaatga acagcgcaag
    20161 aatgatttga ttatgtacct tgcacatgat ttgaaaacgc cgctttcttc cgtcattggc
    20221 tatctaacac tactgcatga tgatgaacaa caaatatcac aggagttaag agaaaagtat
    20281 ctttctattt ctcttgataa agcagaacgt cttgaagatt tgataaacga gttttttgaa
    20341 atcacacgat ttaacttatc taacataaca ttacaataca gcaacataaa tttgacccgt
    20401 ttattagaac aacttatcta tgaatttaag cccatattaa aggaaaaaaa tttgaaatgt
    20461 actctcaata gtacaagcga cattatgcta cattgcgacg caaacaaaat acaacgtgtg
    20521 ttcgataatc tcttgcgtaa tgcggtaatt tacagttata cagatacaga agttgcaata
    20581 accacagaac ttcaagagaa cactattgta attacttttg aaaattttgg gaatcctatc
    20641 gcagaagaaa aactaaaact aatatttgag cagttttacc gagttgacac atcaagaaat
    20701 actacaagtg gtggtgccgg attgggactt gcg
//
