LOCUS       NZ_QSHK01000018        20591 bp    DNA     linear   CON 28-FEB-2024
DEFINITION  Dorea formicigenerans strain AM37-5 AM37-5.Scaf18, whole genome
            shotgun sequence.
ACCESSION   NZ_QSHK01000018
VERSION     NZ_QSHK01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Dorea formicigenerans
  ORGANISM  Dorea formicigenerans
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Dorea.
REFERENCE   1  (bases 1 to 50452)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     A genome reference for cultivated species of the human gut
            microbiota
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 50452)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2018) BGI-CNGB, BGI, No. 11, Beishan IZ., Yantian
            Dist., Shenzhen, Guangdong 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina Hiseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/28/2024 19:12:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,338
            CDSs (total)                      :: 3,277
            Genes (coding)                    :: 3,188
            CDSs (with protein)               :: 3,188
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 12 of 89
            Pseudo Genes (incomplete)         :: 75 of 89
            Pseudo Genes (internal stop)      :: 11 of 89
            Pseudo Genes (multiple problems)  :: 9 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:18:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8890
            Orig. end                         :: 29481
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QSHK01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20591
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     cand_cluster    1..20591
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20591
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10591](+)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10591
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     gene            143..550
                     /locus_tag="DW860_RS15635"
                     /old_locus_tag="DW860_15630"
     CDS             143..550
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338221.1"
                     /locus_tag="DW860_RS15635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15630"
                     /product="phage holin family protein"
                     /protein_id="WP_118145487.1"
                     /transl_table=11
                     /translation="MEKFFCYVLGVLGSFISCVHGKCDIPLRTLILFMVIDYISGIMIA
                     VFFKKSPKSEKGTLKSEVGWKGICKKGMMLIYVFVGVHLDILMNNDYIGNTICIGFIVN
                     ELISIIENAGIMGIPMPTVLKNIIDILNENG"
     misc_feature    652..668
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.99"
                     /tool="antismash"
     gene            654..1196
                     /locus_tag="DW860_RS15640"
                     /old_locus_tag="DW860_15635"
     CDS             654..1196
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS15640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_15635"
                     /product="hypothetical protein"
                     /protein_id="WP_118145489.1"
                     /transl_table=11
                     /translation="MKKYVKCLIMALTVITLSSTAVFAEERSTTETVQETAGLDLSQYK
                     DGEVIPAEAIPDNHYPVINNQEGRSVATSTYTYALKAADSKKMYKCSNLRYKNTDTSMY
                     LKLTKAAGRVGFKGYGRRDNGLSVTSGSAYLSQGQSQYVKQYLFEWGYNEMVGFEATPL
                     SAQTFNATILWSPDVVR"
     gene            1240..1992
                     /locus_tag="DW860_RS15645"
                     /old_locus_tag="DW860_15640"
     CDS             1240..1992
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS15645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_15640"
                     /product="hypothetical protein"
                     /protein_id="WP_118145491.1"
                     /transl_table=11
                     /translation="MKKTNNIQKLSFVLWFIISFNIVKTHIANVVIPIAKYQMNENANR
                     LDYPFSFFSYWIGMDIVNEQNHIYYLLMPILGMLLVMSVPHRNNLKKIALWGGVGAMTP
                     AIVDLVITSYFLPYIKPDASTVYFCLSPLNFCADLFYTSPMMYVLLYVIWGGVIGGIIS
                     IICCLLGIVLKNNIFAFGFLSVFLMMNKEICDLNQWEGYCYYYLVNPGQPVEQLEGADF
                     IRLIAGLIIIIAGVWSIERKKKIEQIDN"
     gene            1955..2524
                     /locus_tag="DW860_RS15650"
                     /old_locus_tag="DW860_15645"
     CDS             1955..2524
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS15650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_15645"
                     /product="hypothetical protein"
                     /protein_id="WP_118145493.1"
                     /transl_table=11
                     /translation="MKEKRKLNRLIIKLVIIGVSILSIWKIVLINTEYSQPSIEEKCMG
                     EVIAITPDVDLKVLSMRIQSIDNINCDEKTKKAIKEIGENVKVANIEVEIKNQGLKDNL
                     IKIYDWVLQNKVWSNGINMELFYGENEKNIDLEILLEKTTCKKIILPFLIYDFQMKKSQ
                     WDTLNSQDFQLVLEHYPVKKIVKMIK"
     gene            2611..4791
                     /locus_tag="DW860_RS15655"
                     /old_locus_tag="DW860_15650"
     CDS             2611..4791
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020498.4"
                     /locus_tag="DW860_RS15655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15650"
                     /product="glycoside hydrolase domain-containing protein"
                     /protein_id="WP_118359812.1"
                     /transl_table=11
                     /translation="MSEAKGDSRVTEVQEWLNETYEAQSWFTKLTVDGMTGAGTCKALC
                     KALQYEIGVKNVDGVIGAGTLAVCPTIGATVTNTNLIKIIQCGFYCKGYECGGITGHYG
                     ATVEIAAQKFKMDAGFDAGNGELQPIFIRALLNTDAFVLVKNGKDYVREAQQYLNNTYI
                     VKLSNWALIPCNGIPDRNMMKAIIAGLQYEEANHSTSGVDGIYGKNTLSKAPTLSSGTA
                     KTAYVKIVQMCLMCMMETNAGMDGAFGSALKKQIEEFQKFYCLSGVTSGTVDRITWASL
                     LSSKGETSRAAKACDTSTVLNYAKAKSLYDAGYRYVGRYLSGTVGGKRSKAMTAEEIAD
                     IFKAGLRIFAIFQEGTPSLNRYTATVGKEEAQKAVMAARQLGIPENAIIYFAIDYDVMD
                     KDIERVKRYFEGIKRVINRYGKYYRVGIYGARNVCTKICESGLAESCFVSDMSTGFSGN
                     LGYKIPKNWAFDQFHEYQFSSLDGTFGLDKNGYSGQYSGFDTVTVDNQMIPDVSDEYRK
                     KKASALLNTIGIPLPSNFQWGNKWTIELPGAEVTICVYKSASKLPSTEGMLSFNISDGE
                     IDTTLEEKMKDVYGKLDSKFTKDIGLTTPSAMFGMATQIENGEISYSYGIDIEGNLIFK
                     CVSKQVLRSEGPVEYSNGYEFEYKIHKSDEQDPETDKVYDFEEIRAKIEAQDPVTQILF
                     FITIIIVAAKAAVELVLTVIRIIVWILGRFLA"
     gene            complement(5340..5894)
                     /locus_tag="DW860_RS15665"
                     /old_locus_tag="DW860_15660"
     CDS             complement(5340..5894)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS15665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_15660"
                     /product="hypothetical protein"
                     /protein_id="WP_005338216.1"
                     /transl_table=11
                     /translation="MKIQTNNTQQPLFINHTVHTKSLLYESITVFHRIILGWIACYSFS
                     ILFLILAYCSFHYFHLILLFLIFTLSAILIPIFWFLLPYQSIHKIYKKNTFLYQSDIIE
                     DIYFFEDYIEIYNLCNHSHMQYHYSEFSFVAHTTHLIVLANTQTHLLINKNGFYKGTLI
                     DFLNFISMKRGKNCNEFKYFI"
     gene            6105..6425
                     /locus_tag="DW860_RS15670"
                     /old_locus_tag="DW860_15665"
     CDS             6105..6425
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024252.4"
                     /locus_tag="DW860_RS15670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15665"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_118145497.1"
                     /transl_table=11
                     /translation="MDYKELGNRVREARTIYGITQSNLAERVGCSVQHISHIETGHTKA
                     SLPLLVKIANTLHVSVDYLLQDSLEENSSELSISIEVRSEKEKTLIYSIVDGLRKGLDN
                     FE"
     gene            6418..7143
                     /locus_tag="DW860_RS15675"
                     /old_locus_tag="DW860_15670"
     CDS             6418..7143
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338212.1"
                     /locus_tag="DW860_RS15675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15670"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_118145499.1"
                     /transl_table=11
                     /translation="MNKQNKNICIHVCDDNPVAIEKAIKITKDLLNEEGLAAEIITYED
                     GNQFTERYKERKDELLILDIDMPGKSGLDILKEFEIHCKNNRVILLTAYDNLALQSLMY
                     GPFQIVRKDLMEIDLEKAIRRFLRIRNEQNAQLEIKEDGMQRVVDIKDIFYIEKRRNYS
                     YIYLKDRRCVKVRKNLRDYEFELAGKGLVRVHAGYMVAMKYCAKIEKGQIVMEDGTEIP
                     ISRDRKNMVKEQFMISRRK"
     gene            7269..7805
                     /locus_tag="DW860_RS15680"
                     /old_locus_tag="DW860_15675"
     CDS             7269..7805
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS15680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_15675"
                     /product="hypothetical protein"
                     /protein_id="WP_118145501.1"
                     /transl_table=11
                     /translation="MEQTVNQAIMECKAGKNREGNLNWIIQKFQPVICKYAGKLYSLEY
                     EDAVQELSEALIMAVVSIDVCNAEGQSIAYLVKGIKLKFYELRRKSIVEYEYRMHSEQI
                     DVNTNITCTDDYSEIEWKLELKKLKDKSSPMECHIIDGMVWEISDVELADLLHVSRQYI
                     NRKRRQLMQRLKDQI"
     misc_feature    complement(7838..7851)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.83"
                     /tool="antismash"
     gene            7892..8599
                     /locus_tag="DW860_RS15685"
                     /old_locus_tag="DW860_15680"
     CDS             7892..8599
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338208.1"
                     /locus_tag="DW860_RS15685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15680"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_118359814.1"
                     /transl_table=11
                     /translation="MLHISICDDEIVAVEKMRKIVGKVLEQEQLLANVGTFENGEEFLN
                     QYIIRDDELVILDLYMPKKNGIDVIKELEKIQRNEVVILVTAYDNLAIQSFSYGPFQIV
                     RKERLEEDLPKAVSRFLKMRQRKQEVLEFQVKGEIIHTKVSDIVYFEKCQHHVYVHLRD
                     RTVLCIRKNMQDFEKELAGKGFVRTHAAYIVALKYCKKFEKNDIILVGDIKIPVSRDRR
                     QMTKEQFMIGRRR"
     gene            8600..9913
                     /locus_tag="DW860_RS15690"
                     /old_locus_tag="DW860_15685"
     CDS             8600..9913
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025854.4"
                     /locus_tag="DW860_RS15690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15685"
                     /product="GHKL domain-containing protein"
                     /protein_id="WP_118145503.1"
                     /transl_table=11
                     /translation="MSNLNYMLSEVGSAFELVLTIEFIIDCLGWKDAIKGKWSKIILFL
                     ILFIIAQGNGRFSNSQIIIVAIDLILFMIYATIFLKGKIQFRLLICAIPFLIVSVINVM
                     IVEVISIMESESVGNLVTNINFSFMIGFFVSKILFYLLLEQVKKLIKNSFQYLQTVQII
                     IISVLIIYSVIMEFCILYLVSKEHVVGIPIILAVVVSCGIIFLSVYMIYSIYRTAKQNI
                     ELIKMNILKIENQETRRQLRELKNSEQRIRKLEHDYKNHCLNIGELLKKEKYCDVESYL
                     KRIIDNYLLSEKIYIETQNSILDAVLNTKIFQAKQEKIDMSCFVVGNLSELDGMDYGSI
                     LFNLLDNAIEATRKNEYVEKKIICNINRDGSKTEIFVKNSIDKSVLQVNKDLITCKENK
                     KLHGMGHQIVKNLVEKMNGLIDFYEEDEMFCVHLYILQ"
     gene            10001..10591
                     /locus_tag="DW860_RS15695"
                     /old_locus_tag="DW860_15690"
     CDS             10001..10591
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009372 - quorum sensing [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016526.4"
                     /locus_tag="DW860_RS15695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15690"
                     /product="accessory gene regulator B family protein"
                     /protein_id="WP_182388480.1"
                     /sec_met_domain="AgrB (E-value: 2.7e-27, bitscore: 86.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISYYAEWIVKKLVRENLIEEREKPIYQYGTEMLIVMILNFFSIF
                     IIGFFSKNLISCILYILIFVTVRTQTGGYHAATYLRCWCLGCTVYLMILVLTEKSPLFL
                     DDTKIIYTLPVIIIAISYHTYILCMLKNKESRKKICVCATARSIGWAGIAVWIQNVFRA
                     TMLVNVIIFTLLAILFFLVIEERRVIWKRRKKC"
     gene            10567..10722
                     /locus_tag="DW860_RS16870"
     CDS             10567..10722
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS16870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_154104350.1"
                     /transl_table=11
                     /translation="METKKKMLVSMQKLIKSTAVNGGGVPSWFMFCNPKIPRELKQLIE
                     DNKKNK"
     gene            complement(10945..>11655)
                     /locus_tag="DW860_RS15700"
                     /old_locus_tag="DW860_15695"
                     /pseudo=""
     CDS             complement(10945..>11655)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1130: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006905733.1"
                     /locus_tag="DW860_RS15700"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DW860_15695"
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="IDAVHFSVRDDGVVRKLAAYVVLGINEDGMKEVLSIVVGENESSK
                     YWISVLNSLKNRGVQDILILCSDGLTGIKDAISAAFSKTEQQRCIVHMVRNTLKYVANK
                     DMKAFAKDLKTIYTAADEEAARKQLKTVTEKWSGQYPSAINRWHDNWDAISPIFKFSKE
                     VCTAFYTTNAIESLNSCYRRLNKQRSVFPSSQALLKALYLETFEIAKK"
     gene            11762..12180
                     /locus_tag="DW860_RS15705"
                     /old_locus_tag="DW860_15700"
                     /pseudo=""
     CDS             11762..12180
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025126.4"
                     /locus_tag="DW860_RS15705"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15700"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRCPNGKNFYLQYRKNVKGNKYGRKEEVYQCEDCSGCPYTEQCKK
                     TDKNRTVRINRELTALHQEVIENLESIQGALLRMNRSIQAEVPLVS"
     gene            complement(12299..12808)
                     /locus_tag="DW860_RS15710"
                     /old_locus_tag="DW860_15705"
     CDS             complement(12299..12808)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS15710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_15705"
                     /product="hypothetical protein"
                     /protein_id="WP_005338202.1"
                     /transl_table=11
                     /translation="MGTLFVNKSGRAFKITRTNGGSDVIGTLPVNAIFAWTDSWAGNGA
                     GADYQGIYCNGMYGWIDGATGTGAFTPLTECGLYNVDVDGDGTVEAVFQTRRAAKYYDK
                     TGKYLGTVPKGYFVATSSNTSGKSHPNLMYVERWGEEDPSNGPMFMDTGMDRYPSFRDC
                     NIIGNL"
     gene            13171..13476
                     /locus_tag="DW860_RS17250"
     CDS             13171..13476
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS17250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_243023947.1"
                     /transl_table=11
                     /translation="MTKSMNGTDKMTEQSVLRLSDAYESKSEELDLELRIRFININPGY
                     NEEMVEKSPTLYQYVKFVDIVRKYQQEMSFPEAVEKAIDECIKNGILAEFLRKNRA"
     gene            13486..13677
                     /locus_tag="DW860_RS17255"
     CDS             13486..13677
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS17255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_242994258.1"
                     /transl_table=11
                     /translation="MSIFEYDEEEHMRQEREESRQESFEQMGELIVKLNQLGRQDDILK
                     VATDAKFREELLEKFHLD"
     gene            complement(13704..14324)
                     /locus_tag="DW860_RS15720"
                     /old_locus_tag="DW860_15715"
     CDS             complement(13704..14324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338199.1"
                     /locus_tag="DW860_RS15720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15715"
                     /product="nucleoside recognition domain-containing protein"
                     /protein_id="WP_117682856.1"
                     /transl_table=11
                     /translation="MLNYLWAGMMMLGIIYAAFTGRMPDITNAALDSSKEAITLCITMI
                     GIMSFWVGLMEIATKAGIIEQLSRKLKPLIHFLFPNLPDNHPAATHITTNIIANILGLG
                     WAATPAGLNAMEELKNLEDDRRKYHLPGKVRAPGTASNEMCTFLIINISSLQLIPVNVI
                     AYRSQYGSINPAAIVGPGILATAISTLVAIIYCKCKEKPDAGH"
     gene            complement(14387..15793)
                     /locus_tag="DW860_RS15725"
                     /old_locus_tag="DW860_15720"
     CDS             complement(14387..15793)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338197.1"
                     /locus_tag="DW860_RS15725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15720"
                     /product="MATE family efflux transporter"
                     /protein_id="WP_117682855.1"
                     /transl_table=11
                     /translation="MNLLHKNNTNALPKAKSTDTHDFGEGSISGNILRLAIPMTLAQLI
                     NVLYNIIDRIYIGHLPDVSTQALTGIGLTLPVITIITAFANLFGMGGAPLFSMARGAGE
                     PGRARKILGNSFSMLLISGGILMVLCYLFKRPLLYLFGASDITYPYANAYISLYLIGTL
                     FVMISLGMNNFINAQGFGMTGMLTVSIGAVLNLILDPLFIFVLHMGVRGAALATIISQG
                     ISAIWVLHFLTGKKAILTLSLAYMKLDFRLVKEICALGLAGFIMAITNGSVQIVCNATL
                     SRYGGDLYVGIMTVINSVREIITMPVTGLTSGAQPVMSFNYGAGKHARVKSAIKFTTIV
                     CILFSCFMWALLLAFPRFFIHMFNSEPELLAEGVPAMHLYFFGIFMMSLQFAGQSTFTA
                     LGKAKQAVFFSLLRKALIVVPLTLWLPTVGGLGTNGVFLAEPVSNFIGGTACFVTMIFT
                     VWRKLDDSLK"
     gene            15890..16417
                     /locus_tag="DW860_RS15730"
                     /old_locus_tag="DW860_15725"
     CDS             15890..16417
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338196.1"
                     /locus_tag="DW860_RS15730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15725"
                     /product="nucleoside recognition domain-containing protein"
                     /protein_id="WP_029731002.1"
                     /transl_table=11
                     /translation="MKLFLYLSDFIVPLMIFGIICYGITMKIPVYDTFVKGAKDGFLTV
                     IKIMPTMVGLMVAVGVLRASGFLEFLAQMIGKVTQYIGFPGELVPLTIVKMFSSSAATG
                     LLLDVYKEYGTDSYLGLVASISMSCTETIFYTMSVYFMTAKVTKTRYTLPGALLATLAG
                     LAASVVLGGVVK"
     gene            16534..17997
                     /locus_tag="DW860_RS15735"
                     /old_locus_tag="DW860_15730"
     CDS             16534..17997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005338194.1"
                     /locus_tag="DW860_RS15735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15730"
                     /product="Wadjet anti-phage system protein JetA family
                     protein"
                     /protein_id="WP_118359816.1"
                     /transl_table=11
                     /translation="MNLISRIPKDFYKVFGSKYMEFYMQFLVEVYEESSQSYSLLGLTE
                     GECQAIMNEQLARMTLDWSEERFDEEGELLTRSNMAMISLRHFEDWGWLRRDYDETLNS
                     YVVSFPEYSQLYVELFRNLYSDEDSKERESVLAVYSHLYTYSSDREKNNDILKSALHTS
                     RSLLQMLANMQEGMRGYFDELSSQRSFLGIQEVLVKEINNSDSQKYAILTTTDSFYRYK
                     EAVKELIEKNLGENETRREGFVEKLRDIQVQLAREEQEKSEERNVQNKLSIQRYRLERA
                     VKLCDEANEMLYRISREFDAIERRYNMLIEQKTVFASRAAARIRYILMEGVVEEDQTIA
                     FVNLLTQSEKRDEILDKLSQKMKLTEPYRVMNEKSLYQRRDRKKEAFVPQAVAEVTEQA
                     DSEEMNEYVLKPLYTQKEIREFRKQNEQDGNFIVTKDTVKSMEDLEKLFLVWQDATEVA
                     EGTEEIEVGEELENENGLRFSKLVIKKSQ"
     gene            18075..18719
                     /locus_tag="DW860_RS15740"
                     /old_locus_tag="DW860_15735"
     CDS             18075..18719
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004847581.1"
                     /locus_tag="DW860_RS15740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_15735"
                     /product="DUF4194 domain-containing protein"
                     /protein_id="WP_040015366.1"
                     /transl_table=11
                     /translation="MVNYMEELSVTEAENLKKTISALFRQTCILQVKYDPVTLTPRDNL
                     HYEICVRHRKFIEDYLSVLGCELVHDPQEHIFRLTGEGVAVERLNVTATKIILLIKIIY
                     RDKILGEGLNATVTNLAEIREYGKNTNLINEKLTMAEWKDALYVMSKHQIIEVPGAIQN
                     VEDQTKIYIYSTINLYCSGVDIQALMKEYVDEEGGAEVEAGEEDIYKNADE"
     misc_feature    complement(19917..19932)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     misc_feature    complement(20417..20429)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(20484..20497)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.74"
                     /tool="antismash"
ORIGIN
        1 aagatttagc gtagtgcaag gcagtattac ggtgaatgtg aagtaaaata taagtagaaa
       61 agcaattaac ggtagtaggt tagttgcttt tttctgttaa attttctttt tatattacga
      121 aatatagaaa agaggtggca atgtggaaaa gtttttttgt tatgtattag gtgtactagg
      181 aagttttatt agttgtgtac atggtaaatg tgatatacca ttgcggacat taatattgtt
      241 tatggttatt gattatatat caggaattat gattgctgta ttttttaaga aatcacctaa
      301 gagtgagaaa ggaactctaa aaagtgaggt gggatggaaa ggaatatgta aaaaaggaat
      361 gatgcttata tatgtatttg ttggtgtgca tcttgatatc ttgatgaata atgattatat
      421 aggaaatact atttgtatag gatttattgt aaatgaatta attagtatta ttgaaaatgc
      481 aggaattatg ggaattccaa tgccaactgt tttgaagaat ataattgata ttttgaatga
      541 gaacggataa atattgcgat agatatacga aaaatcccta aaataacaat aacgaaaaag
      601 caaatagtaa aatgtgaaaa aagggaaacg ttataaagaa aaaggagaaa atgatgaaaa
      661 aatatgtaaa atgtttaatt atggcattaa ctgttattac acttagtagt actgcagtat
      721 ttgcagaaga aagaagtact actgagactg ttcaggaaac tgctggttta gacttaagtc
      781 aatataagga tggagaggta attccagcag aggcaattcc ggacaatcat tacccagtga
      841 ttaataatca agagggaaga agtgtagcta cttcaactta tacatatgcg ttgaaggctg
      901 ctgatagtaa aaaaatgtat aaatgttcta atcttcggta taaaaataca gatacttcaa
      961 tgtatctaaa attgacaaaa gcagcaggaa gagtggggtt caaaggatat ggacgtagag
     1021 acaatgggtt atctgttact agtggaagtg cttatttatc ccaaggacaa agtcaatatg
     1081 taaagcaata cttgtttgaa tggggatata acgagatggt tggatttgaa gcaacaccgt
     1141 tatcagcaca gacatttaat gcaaccattt tgtggagccc agacgttgta agatagaaag
     1201 aataacgttt cccttaaagt tacaaaggaa aggagtatta tgaaaaaaac aaataatatt
     1261 caaaaactga gttttgtatt atggtttatt attagcttca atattgtaaa aacacatata
     1321 gcaaatgttg ttattccaat agcaaaatat caaatgaatg aaaacgcaaa tcgattagat
     1381 tatccgtttt catttttttc atattggata ggtatggata ttgtaaatga acaaaatcat
     1441 atatattact tgcttatgcc tatattagga atgttattgg tgatgtcagt tccacatcga
     1501 aacaatttaa aaaagatagc actttgggga ggagtaggtg caatgacacc ggcaatagtt
     1561 gatttggtaa ttacaagtta ttttttgcca tatataaaac cagatgcatc aaccgtttat
     1621 ttttgccttt caccattaaa cttttgtgca gatttatttt atacatctcc aatgatgtat
     1681 gtattattat atgttatctg gggaggagtt attgggggaa taataagtat tatatgctgt
     1741 ttacttggta tagtattaaa aaataatatt tttgcatttg gatttttatc agtatttctt
     1801 atgatgaata aagaaatatg tgatttaaat caatgggaag ggtattgtta ctattatttg
     1861 gtaaatccag gacaaccggt agaacaattg gaaggagcag attttatacg attaatagca
     1921 ggattgataa taattatagc aggagtatgg agtattgaaa gaaaaaagaa aattgaacag
     1981 attgataatt aagttagtga ttataggtgt atctatatta agtatatgga aaattgtatt
     2041 aataaataca gagtatagtc aaccaagtat tgaagaaaag tgtatggggg aagtgattgc
     2101 aataactcca gatgtagatc ttaaggtatt aagtatgagg attcaatcaa ttgataacat
     2161 aaattgtgat gaaaaaacga aaaaagcaat taaagaaatt ggagaaaatg tcaaagttgc
     2221 taacatagaa gttgaaatta aaaatcaagg tttaaaagat aacttaataa aaatatatga
     2281 ttgggtattg caaaataaag tttggtcaaa tggaatcaat atggagctat tttatggtga
     2341 aaacgaaaag aatatagact tggagatcct tttagaaaaa acgacatgta aaaaaattat
     2401 tttaccattt cttatatatg acttccagat gaaaaaaagt caatgggata ctttgaatag
     2461 tcaggatttc caactcgtat tagaacatta tccagtaaag aaaattgtaa agatgatcaa
     2521 ataaattata tctaagttta caaaccatta tgaaatatct tctttataaa taagtgatca
     2581 ctagaaaaga aataaaggag atgttttaaa atgagtgaag caaaaggaga ttcaagagta
     2641 actgaggttc aggaatggtt gaatgagaca tatgaggcac aatcctggtt tacgaaactg
     2701 acagttgacg gaatgactgg agcaggtaca tgcaaagctt tgtgcaaagc cctgcagtat
     2761 gaaattggcg tgaaaaatgt tgatggagtt attggagcag gaacattggc agtatgcccg
     2821 acaattggag ctacagtaac aaatacaaat ctgattaaga ttattcagtg cggtttctac
     2881 tgtaagggat acgagtgtgg gggaattacc ggacattatg gtgcgacagt agaaatagcg
     2941 gctcagaaat tcaaaatgga cgcaggattt gatgctggaa atggagaact ccagcctata
     3001 tttatccgtg cattgttaaa tacggatgca tttgttcttg taaagaatgg aaaagattat
     3061 gtgcgagaag cacagcagta tttaaataat acatatatcg ttaaattaag caactgggca
     3121 ctaattccgt gtaatggaat tccggaccga aatatgatga aagcaattat tgccggattg
     3181 cagtatgaag aggctaatca ttctacatca ggagtagatg gaatttacgg aaagaatact
     3241 ttatcaaaag cgccaacgct atcttcgggt acagcaaaaa ctgcttatgt gaaaattgta
     3301 caaatgtgtc tgatgtgtat gatggagaca aatgcaggta tggatggagc atttggaagt
     3361 gcgttaaaaa aacagattga agaatttcag aaattttatt gtctttcagg ggtaacatca
     3421 ggaacagtag acaggattac atgggcttcc ttactgtcaa gtaaaggaga aacttcaagg
     3481 gcggcaaaag cgtgtgatac atctaccgta ttaaattatg caaaagctaa gtcactgtat
     3541 gatgcaggat accgatatgt tggaagatac ttatcaggaa cagtaggcgg caaaagatcg
     3601 aaagcgatga cagcagaaga aattgcagat atattcaagg caggattaag aatttttgca
     3661 attttccagg aaggaacacc aagcttaaat agatacacag caacggttgg taaagaagag
     3721 gcacaaaagg cagtaatggc agcacggcaa cttggaattc ctgaaaatgc aattatatat
     3781 tttgcaattg actatgacgt gatggataaa gatatagaaa gggtgaaaag atattttgaa
     3841 ggaatcaaac gagtcataaa tagatatgga aaatattatc gagtcggaat ttatggtgca
     3901 agaaatgtgt gtacaaaaat ttgtgaaagt ggattagcag aaagttgctt tgtaagtgat
     3961 atgtccaccg gttttagtgg aaatttgggg tataaaattc cgaaaaactg ggcttttgac
     4021 cagttccatg aatatcagtt ctcgtcgttg gatggaacgt ttggattgga taaaaatgga
     4081 tattcgggac agtattcagg ttttgataca gtgactgttg ataatcaaat gattccagat
     4141 gtaagtgatg aatatcgtaa gaaaaaagcc agtgcattat taaatacaat tgggattccg
     4201 cttccgtcaa atttccaatg gggaaataag tggaccattg aattaccagg agcagaagtt
     4261 actatatgtg tgtataaaag tgctagcaaa ttaccttcga cagaaggaat gttatcattt
     4321 aatataagtg atggagaaat tgatacaaca ttagaagaaa aaatgaaaga tgtatatgga
     4381 aaattagatt ccaaatttac aaaagatatc ggcttaacaa cgccttctgc aatgtttggg
     4441 atggcaacgc agatagagaa tggagaaatc tcttattcat atggtataga catagaggga
     4501 aatttgattt ttaagtgtgt tagtaaacaa gttttaagaa gtgagggacc ggtagagtat
     4561 tcgaatggat atgaatttga atacaaaatc cataagtcag atgaacaaga tcctgaaacg
     4621 gataaagtct atgattttga agaaattaga gcaaaaatag aggcacagga tccggtaact
     4681 caaatattat tttttattac cataataata gtagcagcaa aagcagctgt tgaacttgtg
     4741 ctaactgtta ttaggattat agtgtggatt ttaggaagat ttttggctta actcataata
     4801 atggaagggc tgttttttgt tacagccctt tcgatatttt tgaattaaaa aaagtggaaa
     4861 aagataaata gttagaagga gttaaaaatt ttttctcaag aaagaagaag tcgtcacatt
     4921 ttagaataag caggtagaga gaggaagttt cataaacacg gcttatagaa tcatatgaga
     4981 tttttatgag agcatgagtg gtgcagtcgt aacaaatata gaaattttca taaaattcaa
     5041 attgcattga aaaagtatgg gagtatttcc ggtaataatt gttatatttt ttttgtacta
     5101 atagtagagg agaaacgaaa taatataaca gaacaataaa actgtagaaa atgaaaaagg
     5161 cagtaatact atactcgtga gaagatatag aaagaaaacc acctaaaaga gaggctatag
     5221 ctgaaataag atagaattta aaagaccatt tggagcgaaa aaaatatgca agttctaagg
     5281 tatatttttt tttaaatgaa cttgaaaaag taaaaagtat atctgattga ttatttgcat
     5341 tagataaagt atttgaattc attacaattt ttacctcttt tcatagaaat aaaattaaga
     5401 aaatctatta aagttccttt gtaaaatcca tttttattta ttaaaaggtg agtttgtgta
     5461 tttgctaaaa caattaaatg agtagtatga gcgacaaagg aaaattctga gtagtgatat
     5521 tgcatatgag aatgattaca taaattataa atttcaatgt aatcttcaaa aaaataaatg
     5581 tcttcaataa tatcggattg atacagaaaa gtattttttt tataaatttt atgaatgctt
     5641 tgataaggta agagaaacca gaaaatcggg attaaaatag cacttaaggt aaatatgaga
     5701 aaaagtagaa taaggtgaaa ataatgaaaa gaacagtaag ccagaatcaa aaaaagaatt
     5761 gagaatgaat agcaggctat ccaccctaag atgatgcggt gaaaaacagt aatagattca
     5821 tagagaaggg atttagtatg tactgtgtgg tttataaata aaggttgctg tgtattattt
     5881 gtttgtattt tcatgaatta taacgtcctc caaacatttt tttaagtata ccatgcttag
     5941 ggactttaaa gaaacagttt tggtacatat agtacaatta tttagctaaa cagtagaatt
     6001 aaactatata gctgataaaa tataaaaact atccctatca atacatttta gattactcaa
     6061 cttatctata gaatggagtg tagaaatgta ttggaggaga aaacatggat tacaaggagc
     6121 tcggaaaccg cgtacgggaa gcgagaacaa tatatggtat tacacagagt aatctggcag
     6181 agagagtagg ttgttctgtt caacacattt cacatataga aacaggtcat acaaaagcaa
     6241 gtttaccatt gttagtaaaa atcgcgaata cattgcatgt ctctgtagat tatttgttac
     6301 aggatagttt agaagaaaat tcatcagaat tatcgatttc gatagaagta cgttcagaga
     6361 aggaaaaaac acttatatac agtattgtag atggattaag aaaagggtta gataattttg
     6421 aataagcaga ataagaacat atgtattcat gtttgtgacg acaatccagt agctattgaa
     6481 aaggcaataa aaataacgaa agaccttttg aatgaagaag gattggcagc agaaatcatt
     6541 acatacgaag atgggaatca gttcacggaa agatataaag aacgaaaaga tgaattatta
     6601 attttggata tagatatgcc gggaaaaagt gggctggata ttttgaaaga atttgaaata
     6661 cattgtaaaa ataatcgtgt tattttactt actgcatatg ataatctggc attacagtct
     6721 ttaatgtatg gtccatttca aattgttcga aaggatttaa tggaaatcga tttggaaaaa
     6781 gcaattcgaa gatttctgag aataagaaat gaacagaatg cacaattgga aataaaagaa
     6841 gatggaatgc aaagagttgt agatataaag gatatctttt atatagaaaa acgacgaaat
     6901 tattcataca tttatttgaa agatcgtcgt tgcgtaaagg ttcgaaagaa tttgcgagat
     6961 tatgaatttg agctggctgg caaagggctt gtcagagttc atgcaggata tatggtagca
     7021 atgaaatatt gtgccaaaat tgaaaaaggt cagattgtca tggaagatgg aacagaaatc
     7081 ccgattagca gagacagaaa gaatatggta aaagagcagt ttatgataag cagaagaaaa
     7141 taaagccttc tgcttttttg atgcgtattt cgacatatat cgacatatgc caatatatag
     7201 ttagaatata ccagcgtgtt gcgtttgttg aaaataattt cttattcctt acaaaggggg
     7261 ataagaaaat ggaacagacc gtaaaccagg caatcatgga gtgcaaggct ggaaaaaacc
     7321 gagaagggaa tctaaattgg ataattcaga aatttcaacc agttatatgt aaatatgcag
     7381 ggaaattgta ttctttggaa tatgaagatg cagttcaaga acttagtgaa gctttgataa
     7441 tggcagtagt tagtatagat gtgtgtaatg cagagggaca aagtattgct tatcttgtaa
     7501 aaggtatcaa attaaaattt tatgaattgc ggagaaagag tatcgttgaa tatgagtatc
     7561 ggatgcattc agaacagatt gatgtaaata caaatataac gtgtacagat gattattctg
     7621 aaatagagtg gaagctggaa ttaaaaaaat tgaaagataa aagcagtcct atggagtgcc
     7681 atattatcga tggaatggta tgggaaataa gtgacgtaga actggcagat ttattacatg
     7741 tatccagaca gtatattaat cgaaaaagaa ggcagttgat gcagagacta aaagatcaaa
     7801 tataaaagca tttgatagaa tgattccaaa gagaaacttg atatggtaca atcgtagatg
     7861 gaaaataaaa ttagggaggt gattttaagg tatgttacat atatcaattt gcgatgatga
     7921 gatagttgct gtggaaaaga tgaggaaaat cgtggggaaa gtactggaac aagagcaatt
     7981 attggcaaat gtagggactt ttgaaaatgg ggaagaattt ttaaatcaat atataatcag
     8041 agacgacgaa ttggtgatat tggatttgta tatgccgaaa aaaaatggaa tagatgttat
     8101 aaaagagctt gaaaagattc agaggaatga agtggtgatt ctggttacgg catatgacaa
     8161 tcttgcaata caatcgtttt cttatggacc atttcaaatc gttagaaaag aacgactgga
     8221 agaggattta ccaaaagcag taagtagatt tttgaaaatg cgccaaagaa aacaagaagt
     8281 gttggaattt caggtaaaag gagaaattat acatacaaaa gtatctgata ttgtatattt
     8341 tgaaaagtgc caacatcatg tttatgtgca tttgcgagat cgaacagttc tgtgcatacg
     8401 gaaaaatatg caggattttg agaaagaact ggcagggaaa ggctttgtga ggacacatgc
     8461 agcatatatt gttgcgctta aatactgcaa aaagtttgaa aaaaatgaca ttattcttgt
     8521 tggggacata aaaattccgg tgagcagaga ccgcagacaa atgacaaaag aacaattcat
     8581 gataggcagg agaagataag tgagcaattt gaattatatg ctaagtgagg taggaagcgc
     8641 atttgaactt gtgttaacaa tcgagtttat tatagactgt cttggttgga aagacgccat
     8701 taaggggaaa tggtcgaaaa ttattttatt tttaatttta tttataattg ctcaaggaaa
     8761 cggtcgcttt tctaatagtc agattataat cgttgctata gatttaatat tatttatgat
     8821 ttatgcaact atttttttaa aaggtaaaat ccaatttaga ttattaatct gtgccatacc
     8881 attcttgatt gtttcggtaa ttaatgtaat gattgtagaa gtaatttcta taatggaatc
     8941 ggaatcagtt ggaaatttag ttacaaatat aaacttttca tttatgatag gtttttttgt
     9001 atcaaaaata ttattctatt tattgctaga gcaagtaaaa aaacttatta aaaacagttt
     9061 tcaatatttg caaactgttc aaattattat aattagtgtg ttgattatat attcggtaat
     9121 aatggaattt tgtattctct atttagtgag caaagaacac gtagttggaa taccgattat
     9181 attggctgtt gttgtgtcct gtggaattat ttttttaagc gtttatatga tttattctat
     9241 ttataggacg gcaaagcaaa atatagagtt aataaaaatg aatattttaa aaatagagaa
     9301 tcaggaaacg agaaggcaat taagagaatt gaaaaattca gagcaacgga taagaaaatt
     9361 ggaacatgac tataaaaatc actgtttaaa tataggagaa ttacttaaaa aagaaaaata
     9421 ttgcgatgtg gagagttatt tgaaaagaat tatagataat tatttattaa gcgaaaagat
     9481 ttatattgag acacaaaatt ctattttaga tgcggtgctt aatacaaaga ttttccaagc
     9541 aaaacaagaa aaaatagata tgtcttgttt tgtagtaggt aacttatcag aattagatgg
     9601 aatggattat ggaagtattt tatttaattt attggataat gccattgaag caactaggaa
     9661 aaatgagtat gtggagaaga agataatttg taatataaat agggatggaa gcaaaacgga
     9721 aatatttgtt aagaatagta ttgataagtc tgtattacaa gtaaacaaag atttgattac
     9781 ttgtaaggaa aataaaaaat tgcatggaat gggacatcaa attgtaaaaa acctagtaga
     9841 gaaaatgaat ggattaattg atttttatga agaagatgag atgttctgtg tacatttata
     9901 tattttacag taaaaaagta gattatatga tttaagttgc aaaatatccc aatttattga
     9961 aaaaaatatt aactgatata atatgaataa ggtgatacac atgatttcat attatgcaga
    10021 atggatagta aaaaagttag taagagaaaa tttgatagaa gaaagagaaa aaccaattta
    10081 tcaatatgga acagaaatgc tgattgttat gattttaaat tttttttcaa tatttataat
    10141 aggctttttt agtaaaaatc ttatttcatg tattttgtat atattgattt ttgtcacagt
    10201 tcgaacacaa acaggtggat atcatgctgc tacatactta aggtgttggt gtttgggatg
    10261 cacggtatat ttaatgattc tagtattaac agagaaatca ccgctttttt tggatgatac
    10321 aaaaatcata tatacattac cagttataat aattgcgata agttatcata catatatctt
    10381 atgtatgtta aaaaacaaag aatctaggaa aaaaatatgt gtatgtgcaa cagcaagaag
    10441 tatcggttgg gcgggaatag cagtttggat acaaaatgta tttagagcaa ctatgttggt
    10501 aaatgtaatt atttttactc tattagcaat attatttttt ttggttatag aagaaaggag
    10561 agtaatatgg aaacgaagaa aaaaatgtta gtgagtatgc agaaattaat taaaagtact
    10621 gctgtaaatg gcggaggagt accaagttgg tttatgtttt gcaatcccaa aattccaaga
    10681 gaattaaagc aattaataga agataataaa aagaataaat aagtggggct gtgtgaatat
    10741 tcttgtgcga tgaaatcgca cttccggaaa tttggacggg aaattctttc tgtaaattca
    10801 gatcttctat gataattgat gcggcttaac agcagatttc tgtgttaagc cgttgtttat
    10861 ttaatagcaa aaataagctg gtatgtcaag agcgcccaga gaaatctggg cgtatattta
    10921 ctcttgatat tccggctttt attgctatat ctgcattctg tccgggtaca tgatttccag
    10981 ttcaccacgg actttgcccc aattacggat tggcattgtc tactttttgg ctatctcaaa
    11041 agtctccaga tatagtgcct tcagcagcgc ctgtgagctc gggaatacgc ttctctgctt
    11101 atttaatcta cgatagcatg aattaagtga ttcaatggcg tttgtggtat aaaacgctgt
    11161 acaaacctct ttggaaaatt taaaaatagg ggagattgca tcccagttat catgccagcg
    11221 atttatagcg ctaggatatt gtcccgacca tttttctgta acggtcttta actgttttct
    11281 ggcggcttct tcatcggcag ctgtatagat tgtttttaag tctttagcaa aagccttcat
    11341 atccttgttt gcaacgtatt taagtgtatt tctcaccata tgtactatgc aacgttgttg
    11401 ttctgtttta gaaaatgcag cagagattgc atccttgatt cctgtcagtc catcagaaca
    11461 gagaatgaga atgtcttgaa ctcctcggtt tttcagacta ttcagcactg atatccaata
    11521 cttgctactt tcattttcac ctacgacaat gcttaatact tctttcatcc catcttcgtt
    11581 aattccaagg acgacatatg cggcaagctt tctgaccaca ccatcgtcac gcacagaaaa
    11641 atgtacagca tcaatggaaa aatatatgaa gtttcccatg ttcaagaaaa agactactga
    11701 caagaaatac catgaagatc catttcgtgc agtaaatttt ccaatcgggg aagacggaat
    11761 catgcgttgc ccaaacggga aaaactttta tcttcaatat cgaaaaaacg taaaagggaa
    11821 caagtatggg cgtaaggaag aagtgtatca gtgtgaagac tgctccggct gtccatacac
    11881 agaacaatgt aaaaagacag ataaaaaccg tactgttcgg atcaaccgcg aacttacagc
    11941 gttgcatcag gaagtgatag aaaatctcga aagcatccag ggagcgcttc taaggatgaa
    12001 cagatccatt caggcagagg tacctttggt atcatgaaaa acgaccggtg gtacaaaaga
    12061 attgtccgaa taggaataaa atctgtattg cttgaagtat ttttcgtttc tattggacac
    12121 aatctttata aatatcgcaa caaacagaaa aagttgcagc tatcgcatag gatttcgtaa
    12181 tagcattctt atgggggaat ggggattata cgcttttttg tgaaatataa ctactgttgt
    12241 atttataaga aaaaggcctc ttttaaatag catttatttt ttgtattgag caatgatatt
    12301 aaagattgcc gatgatattg cagtctctaa aacttgggta acgatccatg ccagtatcca
    12361 tgaacattgg tccattgcta ggatcttctt cgccccaacg ctctacgtac atcaagtttg
    12421 gatgagactt accggaagtg ttgctggaag tagcaacaaa atagcctttc ggtacagttc
    12481 caaggtattt cccggttttg tcatagtatt ttgcagcacg tcttgtctgg aacacagctt
    12541 caacagtgcc atcaccgtct acgtcaacat tgtatagacc acattccgtt agaggtgtaa
    12601 atgctccggt accagtagct ccatcaatcc aaccatacat accgttgcaa taaatcccct
    12661 gataatcggc tccagcgccg tttccagccc aggaatctgt ccatgcaaaa atggcattta
    12721 ctggaagcgt tccgataaca tcagatcctc cgtttgttcg tgtgatttta aaggcacgac
    12781 cgcttttgtt tacaaataaa gttcccataa taatctcctt ttcaattcat aaatgtaata
    12841 atcgattatt caattattaa aaagaaatta tatgtgggaa tgtaaactga attacaaaaa
    12901 aattaaaatg ttaagttgta aattcagaga caattctgac tatattaatt ttagaagaac
    12961 atctagacat aatatatcga ctgtggtaca cttctttcaa gcattatatt tccaagatct
    13021 tgaaggtttg taccatttct aatttcaata cattttctag gaattttcaa tgcttgaatt
    13081 accacgatga acaagcagaa gggattctta gaaagcttag gaacagtcag gaggagagtc
    13141 ctttcgaaca caaaagaaga aggatactga atgacaaaaa gtatgaatgg aacagacaag
    13201 atgacggaac aaagtgtttt acggttatct gatgcttatg aaagtaagtc ggaagaactg
    13261 gatttggaac tgaggatccg attcataaat ataaatcctg gatacaatga ggaaatggta
    13321 gaaaaaagtc cgacattata tcaatatgtg aaatttgtag atatagtccg caaatatcag
    13381 caggaaatgt cattcccgga agctgtggaa aaggcaattg acgaatgtat caaaaatggt
    13441 attcttgcgg agtttttaag gaagaacaga gcataggtgt taagggtgag catatttgag
    13501 tatgatgaag aagaacatat gaggcaggaa cgagaagaaa gcaggcagga aagctttgaa
    13561 caaatgggag aattgattgt aaagttgaat caattgggac gccaagatga tattttgaaa
    13621 gtagctacag atgctaaatt tagggaagag ttattagaaa aatttcacct tgattaaaaa
    13681 ttttatagaa accagatgct gtgttaatgt ccagcatctg gtttttcttt acatttgcaa
    13741 tatattatgg ccactaatgt gcttatagcg gtcgccagta tgccggggcc gacgatggca
    13801 gcaggattga tactgccgta ctggctgcgg taggcaatga catttacagg aatgagctgc
    13861 agggatgata tattaatgat aagaaatgtg cacatttcat tgctggcagt tccgggagcg
    13921 cgcacttttc ccgggaggtg gtatttgcgg cggtcgtctt ccagattttt cagttcttcc
    13981 attgcgttca gtccggcagg tgttgcagcc cagccaagtc ccagaatgtt agcaatgata
    14041 ttcgtggtga tgtgggtggc agcagggtga ttgtccggaa gatttgggaa caggaaatga
    14101 atcagtggct tcaactttcg agaaagctgt tcgatgatgc cggcttttgt tgcaatttcc
    14161 ataagcccta cccagaagga catgataccg atcatagtaa tgcatagcgt gattgcttcc
    14221 ttggaagaat ccagtgcggc attggtgatg tcgggcatgc gtccggtaaa tgcggcgtag
    14281 ataatcccaa gcatcatcat accggcccag agataattga gcataagaaa acctcatagt
    14341 tttcgcttta taaaaactat gaggtttgtg taataagtat gtcatattat tttagagaat
    14401 catccagctt tctccatacg gtaaagatca tcgtgacaaa gcaggcggtt ccgccgatga
    14461 agttggaaac cggctcggca agaaagactc catttgttcc aagtccgcct acagtcggaa
    14521 gccacagtgt cagtggaacg acgatgagtg cctttcgcag cagggagaag aatacggctt
    14581 gttttgcttt tcccagtgca gtaaatgtgg actgtccggc aaactgcagc gacatcataa
    14641 agattccaaa gaaatataaa tgcatcgcag gtacgccttc ggctaacaat tctggttcgc
    14701 tgttgaacat gtgaatgaag aagcgtggga aggcgagcag taatgcccac ataaaacagg
    14761 aaaataagat acagacaatc gttgtaaatt tgattgctga ttttacacgc gcatgtttcc
    14821 cggcaccgta gttaaagctc atgacaggtt gcgcaccact tgtaagaccg gtgaccggca
    14881 tggtaatgat ttcccggacg gagttaataa cggtcatgat tccaacgtac aggtcaccac
    14941 cgtatctgga aagagttgcg ttacagacaa tctgtaccga tccatttgta atcgccataa
    15001 taaatccggc aagtccaaga gcacagattt cctttactaa tcggaagtcc agtttcatat
    15061 aagcaagtga gagtgtaagg attgctttct ttccggttag aaaatgtaat acccatattg
    15121 cagagattcc ttgcgaaatg atggtcgcaa gagcggctcc acggactccc atgtggagaa
    15181 cgaagataaa aagcgggtca aggatcaggt tcaggacagc accgatggag acggtgagca
    15241 ttccggtcat tccaaatccc tgggcgttga taaagttgtt catgccaaga ctgatcatga
    15301 caaaaagcgt gccgataagg tagagactga tgtatgcatt tgcataagga taagtaatat
    15361 cactggcgcc gaacaggtaa agcaatgggc gcttgaacag gtagcacaaa accatgagaa
    15421 taccgccgga aatcaggagc atggaaaagg agttgccgag aattttccgg gcgcgcccag
    15481 gttcaccggc acctcttgcc atagaaaaaa gcggtgcgcc gcccataccg aacagattgg
    15541 caaaagcggt gatgattgta atgaccggca gagtcagacc gattccggtc aacgcctggg
    15601 tggacacgtc tgggagatga ccgatgtaaa tgcggtcaat aatgttgtaa aggacattaa
    15661 tgagctgcgc aagcgtcata ggaattgcaa gacgcagaat atttccagag atgctgccct
    15721 caccaaagtc atgagtgtcc gtagattttg cttttggtaa agcatttgta ttatttttat
    15781 gtaaaagatt caatttcgga aacttccttt ctgatgccgg tatggatttt atcccaccgg
    15841 cataatatac aacagatagt atagggcaag caaaaggaga attcaagaat tgaaactatt
    15901 tctttacctg tcggatttta ttgtaccact catgatattc gggattatct gttacggaat
    15961 tacaatgaaa attccagttt atgacacatt tgtaaaagga gcgaaggacg gatttttgac
    16021 cgttatcaaa attatgccga ctatggtagg gcttatggta gcagtcggag tactaagagc
    16081 atccggattt ctggaatttc tggcacaaat gattggaaaa gttacacaat atatcggatt
    16141 cccgggcgaa ttagttccac tcacaatagt aaagatgttc tcctcgtccg cagcgacagg
    16201 tttactcctt gatgtctaca aagagtacgg gacagattcc tatctgggac tagtggcatc
    16261 aatcagcatg tcctgcacag aaacaatatt ttacactatg agcgtttact tcatgaccgc
    16321 aaaagtaaca aaaacaagat acacactgcc aggggcatta ctggcaacac tcgccggatt
    16381 ggcggccagc gtagtactag ggggcgtagt aaaatagaaa agttacggta gaaaacgcag
    16441 aataactacg tccccaaaag gttgctctta ggggcaaaat tcggtatact gataggagca
    16501 aatcccgtgt gtttgtgggt gaaggaggaa cgaatgaatc tgatcagtcg gattccgaag
    16561 gatttttaca aggtattcgg aagtaaatat atggaattct atatgcagtt tcttgtggag
    16621 gtttacgagg agagcagcca gtcgtattcg cttttggggt tgactgaggg cgagtgtcag
    16681 gcgattatga atgagcagct tgcccgtatg acgttagact ggagtgagga gcgtttcgat
    16741 gaggaagggg agcttttgac gcggtcgaac atggcgatga taagtttacg gcattttgaa
    16801 gactggggat ggcttagacg tgactatgac gaaacgctaa acagctatgt agtatctttc
    16861 ccggagtata gtcagttgta tgtggagttg ttccgtaatc tttatagtga tgaggatagc
    16921 aaggagcgcg agagtgtgct ggcagtgtac agtcaccttt atacatatag ttcggatcgg
    16981 gagaagaata atgatatcct gaaaagtgca ctgcatacgt caagatccct gcttcagatg
    17041 ctggcaaata tgcaggaagg aatgcgcgga tattttgatg aattatcgag ccagcgaagt
    17101 tttttaggaa tccaggaagt tcttgtaaag gaaatcaaca atagtgacag ccagaaatat
    17161 gcgattttga cgacaaccga cagcttttat cgttacaagg aagcggtcaa agagctgata
    17221 gagaagaatc ttggggaaaa tgagacaagg cgcgaaggtt ttgtggaaaa gctccgggat
    17281 attcaagttc agctggcgcg agaggagcag gagaagtctg aagaacgaaa tgtgcagaat
    17341 aagctgagca ttcagcgtta ccgtctggag cgggcagtga agctctgtga cgaagcaaat
    17401 gaaatgttgt accgcatttc cagagagttc gatgccattg agcgaagata caatatgctg
    17461 attgagcaga agactgtatt tgcaagccgg gctgctgcga gaatccggta cattttgatg
    17521 gaaggcgtgg tcgaggaaga tcagacaatt gcttttgtaa atcttctgac tcagagtgaa
    17581 aaacgtgatg aaattttgga caagctgtct cagaaaatga agctgaccga accataccgt
    17641 gtgatgaacg aaaaaagtct gtatcagaga cgtgaccgga aaaaagaagc atttgtaccg
    17701 caggcggtgg cagaggtaac agaacaggca gattcggaag aaatgaatga gtatgttctg
    17761 aagccgcttt acacgcagaa ggaaatccga gagttccgga aacaaaacga gcaggatgga
    17821 aactttattg tgacgaaaga cacagtaaaa tccatggaag atctggaaaa gctgtttctt
    17881 gtttggcagg atgctacgga agttgcggaa ggaacggaag agattgaggt cggagaagaa
    17941 cttgagaacg agaatggtct gagattctct aagcttgtga ttaaaaaatc tcagtaatca
    18001 tcaggtgtaa atatcataga tgggggcttg tgccccaaca tcataataag aaagacaagg
    18061 ataagggaaa acatatggta aattatatgg aagaattgtc tgtgacagag gcggagaatc
    18121 tgaagaaaac catttccgcg ctgtttcggc agacatgcat tttacaagta aaatacgatc
    18181 cggtcacatt aacgccgagg gataaccttc actatgaaat ctgtgtgaga caccggaaat
    18241 ttatagaaga ctatctgtcc gtacttgggt gcgaactggt acacgaccca caggaacaca
    18301 ttttcaggct gaccggggaa ggcgtggctg tggaacgttt gaatgtgacg gctacgaaga
    18361 tcattcttct tattaaaata atctatcggg ataagattct cggcgaaggt ctgaatgcga
    18421 cagtgacgaa tctggcggag atccgtgagt atggaaagaa cacgaatctg atcaatgaga
    18481 agctgactat ggcagagtgg aaagatgcgc tgtatgttat gagcaagcat cagatcatcg
    18541 aggtgccggg cgcgatccag aacgtagaag atcagacaaa gatttacatt tacagcacaa
    18601 ttaatctgta ttgcagtggt gtagatattc aggcattgat gaaagaatat gttgatgagg
    18661 aaggcggtgc agaagttgaa gcaggcgaag aagatattta caagaatgct gatgaataat
    18721 tggggcggtg tcagccacaa gatcatggag ttccatgagt atgtgaatct gttcagtggt
    18781 aagagtggct ctggaaaatc aacagttatg gatgccattc aagtcgttct gtacggaagt
    18841 atttccgcta catttttaaa taaggcggcg gacgatgcga agaaccgccg aagtgtgctc
    18901 agttacctgc gaggtgcgca gaaagacggt tcttacaatc gtgatggaca ggatttctgc
    18961 tctcagatcg tactggagat atttgatacc ggaacgaagg tgagcacttg tatcggtgtt
    19021 gcattcgaag ttggaaaaaa tgataccgat atccggaagt atacattttt cagtcactcc
    19081 gggaaaattc cggaggacga gtatctgacg gagaaaggtg tgccatatac aattgcagga
    19141 ctcagaaagc ttgtggaaaa gcgggtggat tcttcggaca atcgtggacg aggtgatgtg
    19201 aatcgtcttt atccgtcaaa agaggcatat ctgaaaacgg tttatgatgt gatatttgga
    19261 tatgtggagc cggggcgcat gatgaccatg gaaaagagtg cgattgccct tcgcatgaca
    19321 aatggaacgg gtcagtttat ccgtgattat atgttcccga agagtaagga ggacacggtt
    19381 tcgaccatca gtgaccagct tggtgcgtac cgtgagatca aagagcgtgt ggaagacctg
    19441 gagaatcgga ttcatcttct ggatgagatc agccggcaga atctggcact tcagacgacg
    19501 cgtgcggata agctccatgt ggaacaggtg ttaaaatata ttgatattga aagcttcaag
    19561 acgaagattg aggcgagaag tcaggatctt atggatatca atgagaagat tcgtgccaga
    19621 gaaaaacagc agaatgagaa taatgagaaa aagacacagc ttacgaacgc acttgtagag
    19681 gtagaagcgg aactaaaatc cagtgattat ggtcagaagg agaaggagct gaagagtctt
    19741 aaggagacca tcaagcttct ggcccgcaac agtgagcagt ggcgcgaggt tgtaaaagga
    19801 cttgtccgct gggaggaaga tgaagagatc agtgcctatg tgagcaatcc ggcacttcag
    19861 aggattgatg agatcaagtc gggaaatgtt tcaaaggaag caattgagaa gctaaagaaa
    19921 caactaagtg acgcgctgga gagcattaat gaagaagttg atgaaatcgg tacaagaatc
    19981 agtcagaacc gcaaggattt gaaagagaaa aaggaaatgg tggaggatct gaaaaacgac
    20041 cgcaaaccgt accgaaaaga gttaaaacag gcaaggcagg agttacagaa ccgtctgagc
    20101 acacaatatg gaagaaccat tcacgtcaac attttcgcag acctttttga tattacagat
    20161 gagaagtgga aaaatgcgat tgaaggtcgt atggggcgtg tgaaacacag tcttgtgacc
    20221 gcaccggagt acgcccttga tgcagcgaaa gtatttcgta agcttcaata tcttggtggg
    20281 attgatgaag tagatctgtt agatacggcc gcaattgtga agtccgagcc aaaagttcat
    20341 gacaattcga tctatgaggc tgttcatgca gaagaaccat acgtggacca gtgcctgcgc
    20401 cgttatctcg gaagaattgc caaatgcgag acagaggaag aactccgtgc ctccggaaat
    20461 ggtgtgacag ccgactgtta ttcttataat aattacattt tccgtcatct gaagaaaaat
    20521 gattacgaaa aatatgcctg cattggaacg aaggtttcta aggcaaagct tcgtgaaatg
    20581 gaagatgagg t
//
