LOCUS       NZ_QSHK01000002        32063 bp    DNA     linear   CON 28-FEB-2024
DEFINITION  Dorea formicigenerans strain AM37-5 AM37-5.Scaf2, whole genome
            shotgun sequence.
ACCESSION   NZ_QSHK01000002
VERSION     NZ_QSHK01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Dorea formicigenerans
  ORGANISM  Dorea formicigenerans
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Dorea.
REFERENCE   1  (bases 1 to 417757)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     A genome reference for cultivated species of the human gut
            microbiota
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 417757)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2018) BGI-CNGB, BGI, No. 11, Beishan IZ., Yantian
            Dist., Shenzhen, Guangdong 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina Hiseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/28/2024 19:12:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,338
            CDSs (total)                      :: 3,277
            Genes (coding)                    :: 3,188
            CDSs (with protein)               :: 3,188
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 12 of 89
            Pseudo Genes (incomplete)         :: 75 of 89
            Pseudo Genes (internal stop)      :: 11 of 89
            Pseudo Genes (multiple problems)  :: 9 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:18:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 198377
            Orig. end                         :: 230440
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QSHK01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..32063
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="cyclic-lactone-autoinducer"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..32063
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="cyclic-lactone-autoinducer"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..20742
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20742
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10742](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10742)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     gene            complement(233..934)
                     /locus_tag="DW860_RS04600"
                     /old_locus_tag="DW860_04595"
     CDS             complement(233..934)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015528792.1"
                     /locus_tag="DW860_RS04600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04595"
                     /product="response regulator transcription factor"
                     /protein_id="WP_005330396.1"
                     /transl_table=11
                     /translation="MNKSLILVVEDDTSVRNLITTTLKTHEYRYLTAPDGQSAILETSS
                     HNPDIVLLDLGLPDIDGVEIIKKIRTWSNMPIIVISARSEDTDKIDALDAGADDYLTKP
                     FSVEELLARLRVTQRRLSMMQKVSPAEAVVFVNGKLRVDYAAGCAYLNEEELHLTPIEY
                     KLLCLLTRNIGKVLTHTFLTQSIWGSSWDNDIASLRVFMATLRKKIEKEPNSPQYIQTH
                     IGVGYRMLKVD"
     gene            complement(927..3626)
                     /locus_tag="DW860_RS04605"
                     /old_locus_tag="DW860_04600"
     CDS             complement(927..3626)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005330395.1"
                     /locus_tag="DW860_RS04605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04600"
                     /product="sensor histidine kinase KdpD"
                     /protein_id="WP_118358394.1"
                     /transl_table=11
                     /translation="MSESRHNPDQLLKEIQADEEKRNKGHLKIFFGYAAGVGKTYAMLE
                     AAHMEKQKGIDVVAGYVEPHARPKTAALLNGLEVLPTREVFYNGMILDEFDIGMALKRK
                     PQLILVDELAHTNAEGCRHAKRYQDIKELLNAGIDVYTTVNVQHIESLCDTVASITEIV
                     VRERIPDSIFDNADQVELIDIEPQDLINRLNTGNVYRQTQEKQAVENFYTIENLTALRE
                     ISLRRCADRVNILTENTRIKNHGDYHTGEHILVCLSSSPSNAKIIRTAAKMASAFKGEF
                     TALFVETPDFSVMSEENVKRLRSNICLAEQLGAKIETVYGEDVPFQIAEFTRLSGVSKI
                     VIGRNSATKRHLLSKPTLTEKLIDYAPNLDVHIIPDTVSNATVYQLRGGRKKNHIVFSV
                     TDTLKSTAILILSSLVGMIFQKFGFDEANIITVFVLGVLVTAVITKHQIYSLISSIVSV
                     LVFNFLFTEPQFTLQAYDHGYPVTFIIMLLAAFLTGSLAIRIKNQAKQAAQSAYRTKVL
                     FDTNQLLQQAKDKNEIVSATSNQLIKLLRKDIVFYLADGEVLDTPHIFSVTEENLESCI
                     SENEKAVAGWVLKNNKRAGATTGTLSNAKCLYLAVRSSSMVYGVIGIVMGEIPLDPFEN
                     SILLSILGECALALENEKNAREKQEAAILAKNEQLRANLLRAISHDLRTPLTSISGNAS
                     NLLSNGDSFDNDTKKQLYMDIYDDSMWLINLVENLLAVTRIEEGRLNLRIMEDLMDDVI
                     TEALHHINRKSEEHHISVESKEEFLLAKMDAKLIVQVIINIVDNAIKYTPKNSHIVIRT
                     EKRGKQAIVSISDDGNGIADEIKPRIFDMFYSGANQIADSRRSLGLGLSLCKSIINAHG
                     GELTVSDNLPHGTVFTFTLPAGEVKVYE"
     gene            complement(3717..4277)
                     /locus_tag="DW860_RS04610"
                     /old_locus_tag="DW860_04605"
     CDS             complement(3717..4277)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005330392.1"
                     /locus_tag="DW860_RS04610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04605"
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="WP_243023819.1"
                     /transl_table=11
                     /translation="MKEVGDMKDFVLLIVVLVAFIYGYFLMEKLDKFLKENQSQKLISD
                     SKLRIGFETPAIIDSIADLLEQFSSEYPNYELNMFYGSVSEIINGLENNKLDFGFIIEN
                     SNDILKDEYCSLSFQIKQSVITLGSIDIAVHPINTIEKPARVIWQNDINCMKGLFVEKL
                     RDFSERFLLSATRPNGKKEEKVV"
     gene            complement(4281..4928)
                     /locus_tag="DW860_RS04615"
                     /old_locus_tag="DW860_04610"
     CDS             complement(4281..4928)
                     /GO_process="GO:0006813 - potassium ion transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005330390.1"
                     /locus_tag="DW860_RS04615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04610"
                     /product="TrkA family potassium uptake protein"
                     /protein_id="WP_117494498.1"
                     /transl_table=11
                     /translation="MKSILLIGLGRFGRHIAIKLDELHHQVMAVDKEDTRVDAVLPFVT
                     NAQIGDATNEDFLSSLGVGNFDVCIVAIGDDFQNSLEVTSLLKELGARMVVSRAARDVH
                     AKFLLRNGADEIVYPERQLADWVAIRYSADHILDYIELDEEHAIFEISIPGEWIGKTIG
                     QLNIRKKYNINIMALKTNDIMNLKISSDTQLLKNSTMLVLGEKKHIQKCFHI"
     gene            complement(4942..6282)
                     /locus_tag="DW860_RS04620"
                     /old_locus_tag="DW860_04615"
     CDS             complement(4942..6282)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015514823.1"
                     /locus_tag="DW860_RS04620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04615"
                     /product="potassium transporter TrkG"
                     /protein_id="WP_118358392.1"
                     /transl_table=11
                     /translation="MQQKNRSRHRHITSFQVISLGFLSVILLGSLLLMLPIATKSGQCT
                     SFLDALFTATSAVCVTGLVVNDTATYWSLFGQGVILLLIQIGGMGIITIAIAIAVVSGR
                     KIGLMQRSTMQEAISAPTVGGIVRRTQFIIRTTILIEIIGAVLLAPVFCRDFGFWKGIW
                     YSLFHSISAFCNAGFDLIGIRTPFSSLTSYSVQPIVNLVIMMLIIAGGIGFLTWEDIKN
                     HKWHFKKYRMQSKVIFMVTGLLIFLPALYFFYFEFSNVPLMERVWISLFQSVTPRTAGF
                     NTADLTLLSEVGQMLIIMLMLIGGSPGSTAGGMKTTTLAVLVSSALSVFRKKEHTHFFG
                     RQIPDGIIRNAATIFLMYIVLFLVGGMVISSTEDIPLMIALFETASAIGTVGLSLGITP
                     DLGLVSHIILICLMFFGRVGGLTLIFATISEKKPNGSKYPQEKITVG"
     cand_cluster    5882..32063
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    5882..32063
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[15881:22063](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(15882..22063)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="2"
     gene            complement(6581..8473)
                     /locus_tag="DW860_RS04625"
                     /old_locus_tag="DW860_04620"
     CDS             complement(6581..8473)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613394.1"
                     /locus_tag="DW860_RS04625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04620"
                     /product="recombinase family protein"
                     /protein_id="WP_118404095.1"
                     /transl_table=11
                     /translation="MEVEIIKANSYDEDISNGRRIDRLRVAAYCRVSTDDEDQIKSYNS
                     MVRYYTDLIKSNKQWVFAGVFADKAITGTKTDKREEFQLLIQECLSGNIDMVIAKSIPR
                     FARNTLDTLKYVRMLRERNIAVYFEVEKINTLKDGEFLLTILSSVAQQEVENTSAYVKK
                     GLKMKMKRGELVGFQGCLGYDYDVVTKSLSVNEEGAETVRYIFDRYVAGAGSTMIAREL
                     NEQGIPTIKGNPWTSSSVMGIINNEKYKGDILLGKTFTVDPISKRRLENLGEEDRFYIK
                     NHHEAIISEETFARAQEIRERRNGGRKKGVAPGKREKFSRQYAFSCMLECGFCGANLSR
                     RRWHSSSKYTKTIWQCVESTKHGKRFCPDSKGIPEQVIEDAFIESYRMLCMDHKDVLEE
                     FIKRVEKTLLEDSIEDKIEKLNRSVYNIQYKRKKLLENYLEGVVAKDIYEETDMGYEKQ
                     LSEAKSQLSMLEQQYDNEGSLQRRLADFKKALSKNQVLEEFDRGIFESIIEKVIVGGYD
                     ENGEKDPYKIIFIYKTGFKNEIGNAKERFGKKSKAVETVKEMCSHIVDEVKDVCSYVSD
                     NTCGSRVLSTSGEFVEVLNFRHFARYMSFTPTGKQGKKKQIMNGIEVSVVLHLV"
     gene            complement(8543..8692)
                     /locus_tag="DW860_RS04630"
                     /old_locus_tag="DW860_04625"
     CDS             complement(8543..8692)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613393.1"
                     /locus_tag="DW860_RS04630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04625"
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_117638655.1"
                     /transl_table=11
                     /translation="MNSTKLLRYSMQLSMLKQLRSLELINENEYRLIEKKLKKDYGVIS
                     NITA"
     gene            complement(9079..9330)
                     /locus_tag="DW860_RS04635"
                     /old_locus_tag="DW860_04630"
     CDS             complement(9079..9330)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613390.1"
                     /locus_tag="DW860_RS04635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04630"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_044924637.1"
                     /transl_table=11
                     /translation="MKTEEKSVNNKKLIPFWVIERALEGDIQAINKILKHYEGYIAKLS
                     VRKMYDEYGCVHYCVDETLRRRLETKLIKTIIGFKIVR"
     gene            complement(9302..9754)
                     /locus_tag="DW860_RS04640"
                     /old_locus_tag="DW860_04635"
     CDS             complement(9302..9754)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613389.1"
                     /locus_tag="DW860_RS04640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04635"
                     /product="sigma factor-like helix-turn-helix DNA-binding
                     protein"
                     /protein_id="WP_118404097.1"
                     /transl_table=11
                     /translation="MEQSSSYDEKTVMHQFDRKCKLALKGETVDYERHLAYLRKHETLF
                     SELSEQEMESLSLFDEYELEKSYFRAGGYDVEVKNALLAEALTALTERKRDIILLSYFM
                     EMNDADIARKLNLVRSTVHEHRTRSLEILKIMLEENAGENGRKKRK"
     gene            complement(10001..10591)
                     /locus_tag="DW860_RS04645"
                     /old_locus_tag="DW860_04640"
     CDS             complement(10001..10591)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005421682.1"
                     /locus_tag="DW860_RS04645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04640"
                     /product="accessory gene regulator B family protein"
                     /protein_id="WP_117638657.1"
                     /sec_met_domain="AgrB (E-value: 4.2e-32, bitscore: 105.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLSEKIAKYVIKTGVVSPELYVVYQYGFQIGLEMLCCFVTCLS
                     IAIYMHMIPEFAIFTGIFMLLRTYAGGVHLNSFGSCFICSVTVQIIAMYFNSKYKFTVG
                     TAWILILVSAILILKAAPVECINRELDDTEKEHCKKVTMKVLSAVIVFAGCCTLAGIPD
                     ILSLVALTSFIILISQYVGILKYKIEKSKNKRR"
     gene            complement(10593..10742)
                     /locus_tag="DW860_RS04650"
                     /old_locus_tag="DW860_04645"
     CDS             complement(10593..10742)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543498.1"
                     /locus_tag="DW860_RS04650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04645"
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="WP_117638658.1"
                     /sec_met_domain="TIGR04223 (E-value: 2.8e-15, bitscore:
                     50.7, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLKDVKKQSAKMLASVSLKLGKMSADSACCYIYHQPKMPEALKN
                     MKQS"
     gene            complement(10889..11278)
                     /locus_tag="DW860_RS04655"
                     /old_locus_tag="DW860_04650"
     CDS             complement(10889..11278)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS04655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_04650"
                     /product="hypothetical protein"
                     /protein_id="WP_118404099.1"
                     /transl_table=11
                     /translation="MEKILLFSDDEKLFEITKQVTEGKQELIWGNYQCLETNGYPFADV
                     VIMHFDEDKIRKDILQPIIKVKGRLGHLTPILAVIENGSMQDIFSVLKIGVYDYIETID
                     DLEKYQKKIQDIILWDWYLKKYKGG"
     gene            complement(11378..12685)
                     /locus_tag="DW860_RS04660"
                     /old_locus_tag="DW860_04655"
     CDS             complement(11378..12685)
                     /EC_number="2.7.13.3"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543496.1"
                     /locus_tag="DW860_RS04660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04655"
                     /product="sensor histidine kinase"
                     /protein_id="WP_117638660.1"
                     /transl_table=11
                     /translation="MWIDKALPYGADILLSAYAVYLFFYYFDIFFARKKSKKLWVAGLT
                     EFVLWQFGISTIISLPAYVNIAVTVIVTLFAVTITYEGMWWNKCVFVITFNAIWMLMET
                     LSNYVLMIYCEQYASIQPIGSFVSKSFFLAVIIALKKVFTDDEIKELSVRYSIMLVLIP
                     MGSIYIMNNVFMLGFTVNDNHTRINSAITVIILLVMNILIFYIYMKLADDLRLRRMASV
                     YEQQLELCERHQQEREISILQLRDAKHNMKNNLVSILAYAENRQHEKIIGFINEIMEES
                     GMAIAAISNSGNIVIDSLIGYWYVTAKKKEIDFKTDICIPMMLPFKGADICLILGNLLE
                     NAVEAAQKVDGKKYIEIKMKYDKNNILLSVTNSYSGKLLKTKDHRLKSTKTDTENHGVG
                     LASVYRAVAKYCGTIIIDDSVSGQFKIRVLLYGNQE"
     gene            complement(12672..13400)
                     /locus_tag="DW860_RS04665"
                     /old_locus_tag="DW860_04660"
     CDS             complement(12672..13400)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337549.1"
                     /locus_tag="DW860_RS04665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04660"
                     /product="LytTR family DNA-binding domain-containing
                     protein"
                     /protein_id="WP_015543495.1"
                     /transl_table=11
                     /translation="MLNIAICDDDIQTTGQIEMMIQKIAKRNFADVDIEVFWNGESLAD
                     SVVAGDGYDIIYLDIEMNNEDGISTAKRIRKYDKNVLIIYVTSHENYMKESFSVRPFQF
                     LVKPVSEKQMETCFMAAYEDINSGDFYFRYSYQRMNHKVLIRDILYFESSKRKVFIVTR
                     EETFEFYGKLNEIENSLKVCKISFLRVHQSFLVNYKHIKGQSYDFVVMDNGKKISISED
                     RRKLISEQYCSMEDTYYVDR"
     gene            complement(13406..13780)
                     /locus_tag="DW860_RS04670"
                     /old_locus_tag="DW860_04665"
     CDS             complement(13406..13780)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337551.1"
                     /locus_tag="DW860_RS04670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04665"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_117638661.1"
                     /transl_table=11
                     /translation="MESRIKQLREKRGLIQEILAAELGITQQMLSKYERDVTLIKVDIL
                     KKIATYFNVTTDYLLGVSDVKRDLQRQMKMNETLDEYYDLIEIYKDLDSYDKEMIWSIM
                     QTVKKVGEKRKKDNKLIEES"
     misc_feature    complement(14550..14561)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            14677..14883
                     /locus_tag="DW860_RS16890"
     CDS             14677..14883
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS16890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_207662197.1"
                     /transl_table=11
                     /translation="MTVPAVIKELEKIEMTRQTDNVYRLDHAVTAKQKKILKAFGMNEG
                     NITYRVGEISNTLKKSNIQKEWR"
     gene            14886..15113
                     /locus_tag="DW860_RS04680"
                     /old_locus_tag="DW860_04675"
     CDS             14886..15113
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS04680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_04675"
                     /product="hypothetical protein"
                     /protein_id="WP_117638662.1"
                     /transl_table=11
                     /translation="MAREINAELLDTKIEKAQQDLAKAKHLYDAVAATLKDLLDKRDSL
                     RQKKLLDAIAQSGRSYEEIKQYLHSKSEAV"
     gene            complement(15395..15772)
                     /locus_tag="DW860_RS04690"
                     /old_locus_tag="DW860_04685"
     CDS             complement(15395..15772)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543488.1"
                     /locus_tag="DW860_RS04690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04685"
                     /product="hypothetical protein"
                     /protein_id="WP_118404103.1"
                     /transl_table=11
                     /translation="MDKITHKVRCEQWTNIIKECLTSGMSKTTWCREDGISDKSFFYWQ
                     RILREEAYLSTLENTLTPAVKENSVPTTTDFVEIKMTDHTSSSASPFKPDVVIRRGSVS
                     IEISNKATEELLNKVGGLLHA"
     gene            complement(15882..17204)
                     /locus_tag="DW860_RS04695"
                     /old_locus_tag="DW860_04690"
     CDS             complement(15882..17204)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="DW860_RS04695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04690"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_173864587.1"
                     /sec_met_domain="LANC_like (E-value: 3.8e-65, bitscore:
                     214.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MECDILTMTKNIATNLSDYERMLKIMGRKENQRTWEGIEFEAFSP
                     LTLSHGLPGICLLYGKLMECCPKEDKWGRFAHNYLSLMVEELNKKGFQSLSMFSGAAGV
                     ALSVASVSNDFLNYNKLLNTLNDYILNRFEESYSNIVKEEGTHSLYYDVIEGLSGVLSY
                     LGIYRNQRKYYNVITRGLEILVNLTKDIEIQGQVVPGWYIPVQNQFSELEQDLYPKGNF
                     NTSLSHGIAGPLTILSDMMANGIIVDGQEEAIIKIIKFLFDFKLNDGERDFWKGQIDFD
                     EVVNKKLTDENIIRRDAWCYGNPGICYAIVSAGNALDNQFLIDYGIENLRLTMNNIKGI
                     FSPTFCHGYAGLYQVLNSVEMLLQKEFFSLEKELLKNKITDFYNPDYIYGFKNMELDNK
                     MEKIKPYDVCGLLEGTTGVCLSLLEGEKKSDNLWKKAFLLA"
     gene            complement(17209..19011)
                     /locus_tag="DW860_RS04700"
                     /old_locus_tag="DW860_04695"
     CDS             complement(17209..19011)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543486.1"
                     /locus_tag="DW860_RS04700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04695"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_117638664.1"
                     /transl_table=11
                     /translation="MNNKKVGFKEVWRALKQIPKTITIIRKVDKKGFTLIVMLSMIAGA
                     FPVITLVLSQELINSIVKKSSPLRYTIILFTIYIIVSFLGSILGEAKDYIESKFQYVLQ
                     YKLNYLIMDKCTKLTLKDFETPAMYDKIEKITGEVAYKPYQIMIAIIGIITSVVTMLSS
                     AFLLFAWNPYISMLLLVVPIISMLYYLKIGQQEFEIMWNRAKDERKTWYLTYLLTHDFS
                     FKEISLLDLKDYFLKKYWSISALFIRQNTSILKRKTLFNILYELSIQIVSAIIIGVAIM
                     SAYVGEILVGNVMSYIRSVGLVQTNSQAIMSNIYTVYSSTLYMDMLFQFLNYCVKEDSS
                     EKIVMKEPINKIDIKELSFSYNGKTKVLDKINLTLVQGEKVALVGPNGSGKSTFLKILA
                     GLYNIEEGEILINGRSLIDLDIRSYRSKMSVLFQDFVKYELSLRENIGFGDIQNLNNDE
                     KMVQMLHKLQTKFLQTDNGSYNLDLQLGNWFEDGCQLSQGQWQKIALGRVYFRDASFYI
                     LDEPNAALDTVSEREVFEKFFELSKDKIGVFISHRLNAAKMADKIIVMDQGKIVGIGKH
                     DELLRNCMTYQKLYKAESYEREDM"
     gene            complement(19004..22063)
                     /locus_tag="DW860_RS04705"
                     /old_locus_tag="DW860_04700"
     CDS             complement(19004..22063)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="DW860_RS04705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04700"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_118404105.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.3e-126,
                     bitscore: 415.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.2e-13,
                     bitscore: 45.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6.3e-30, bitscore:
                     99.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNLYYNTQKFMFRIPNDVERKLDFTEEEIKNACLDAKFREKVSI
                     ASPALVDMMDLYIKNPEKLSEKKLVNFQNSIMKYLIRSKNRTTPFGLFSGVGLGKFGDS
                     DTFDVSGAKYQKKVNIDSEWLFGFISQLEKIKSQRLRFKINDACYIKGNRAILLYSTEK
                     EIEEISVRATRVFEIIYESCQEFKEYNQIARIIEEEYPNVPNEKVTFYLNELISKEILI
                     SDLRPSLNSRNQIAYVIERLRESALFEEAGNIIEISKMCTSYMNLPVGEGITLYDKIVS
                     KMKLLYSCSSYLQVDTVIENAEFEIKSTVANKINRLASFFVYISNDKNESHTYLDEYRN
                     KFIEKYGVDREVPLLEMLDSNIGIGAPTSYLNPQNDFFEEDSTKPNYNLRLKNYLLNKY
                     ESAITNKTSITLEQDEIEGILKREIKTDEVPISLELYFQLKKRNDELNLCLGPNCGSLV
                     AGKTFGRFSTISDEFADMLEDINKEERRLRDDNIEMCEIGFLPAPARNGNIVRTRTFRE
                     KKTVIFTAADKGTTDVINIKDISIGVFNELFYARDYKTKKLVVFESNNMYNPMLNPNIL
                     RFLQDISHEGKRSWSEFPWTYIFSEFRHVPAIKFEDIVIENEKWKLNLSEMRLEKKNFE
                     EFKCKFLQLIKDKNIPDDIYLTEADNRIKLDLKKELSIRIIFDEFKKHGSRDLILERAE
                     TGENITYSGEGGHTTEIVVPLFRKEKELQNVYPAEKVIIERKKHLELPFENWLYFNLYC
                     NSNREDELIAFDIMDFCEELKKKYDVDYFFMRYVDPKPHVRLRIKGTQEVLLQIYPLII
                     KWQHQLLDDGIIGDLKISIYDREIERYGGVHLMDIAEQVFFIDSFIVESILRMKRLGVL
                     AMDQEDIAIISIIMYIQGFYENFEEQMNFLAINYHTSDFMSEFKKKKQRLVSLCGCEND
                     WKELLSNEEGTFLYNLLNMRTVVLNKYRDEINNINQDPLFKNGIVASVIHLHCNRIIGT
                     DRELERKLMAFSESIMYAKRYIMKRNEDHE"
     aSDomain        complement(21380..21637)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DW860_RS04705_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="1.60E-14"
                     /identifier="RREFam001.1"
                     /label="DW860_RS04705"
                     /locus_tag="DW860_RS04705"
                     /protein_end="228"
                     /protein_start="142"
                     /score="45.4"
                     /tool="antismash"
                     /translation="KINDACYIKGNRAILLYSTEKEIEEISVRATRVFEIIYESCQEFK
                     EYNQIARIIEEEYPNVPNEKVTFYLNELISKEILISDLRPS"
     misc_feature    complement(22103..22117)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.15"
                     /tool="antismash"
     gene            22185..22388
                     /locus_tag="DW860_RS04710"
                     /old_locus_tag="DW860_04705"
     CDS             22185..22388
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DW860_RS04710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DW860_04705"
                     /product="hypothetical protein"
                     /protein_id="WP_117638666.1"
                     /transl_table=11
                     /translation="MKTKEELLLSVKEDIEAFGKDKLVYAHMSLQNEGTILYGYSYTPE
                     GKFIDEASLEELLIILESDTDM"
     gene            complement(22436..23794)
                     /locus_tag="DW860_RS04715"
                     /old_locus_tag="DW860_04710"
     CDS             complement(22436..23794)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="DW860_RS04715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04710"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_118404107.1"
                     /transl_table=11
                     /translation="MGYKIITMKRQLLLYLIKLFVGIVVIIICWLALTNIFVECGVIIP
                     ANYSETILEENRKRLDDIQQITDNDLPYGSKYSIFDLDYNYERGTMNKSDIEVTKKILL
                     GKESNLQGNYVYSVIARTEEYCVIKYNIKARFNSDNRIFNYIDYDNLSYITMVLVFLLY
                     VYIMTLHLVSIWKNNFEKIEKITLEIEKQNLDFTYEESKIKEFSNIITALIKMRDALKE
                     SLYQTWKIENEKNEEIAALAHDIKIPLTIISGNTELLKCYSSDEYSLSHLQSIWGAVGK
                     MEEYVNLLIKYVKADRIDFHEKESMPCNSFSHKIVSEIKEYISGSEEIIKFNVEKVRGT
                     IKIDYISLERAIFNIIDNAIEYKVYGDKIMCFIGQKDDSYIFTICNEKGEFSSQVLENG
                     TKLFFTSNNNRNSIHYGIGLAYANKVIQSCEGELELYNSKEHGAVVSIKLPIT"
     gene            complement(23779..24444)
                     /locus_tag="DW860_RS04720"
                     /old_locus_tag="DW860_04715"
     CDS             complement(23779..24444)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015543482.1"
                     /locus_tag="DW860_RS04720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04715"
                     /product="response regulator transcription factor"
                     /protein_id="WP_118404109.1"
                     /transl_table=11
                     /translation="MEKILVIDDDEKILELVQEVLKNEHYIVETRSYVDNTNIGEFEGF
                     DLILLDIMLPFLDGYEILERIKNIITCPVIFLSAKSSEGAKVKGLMSGADDYITKPFSI
                     RELVARVKVALRRSLKNESNGILINGLVFNQDSNSIKLDNGEILLTKNEFRICKILVQN
                     SGKIFSKNELYEYLYDLDANAQLRTITEFIYSIRKKFKTLGLDPIKTIWGIGYKWDIK"
     gene            24652..26202
                     /locus_tag="DW860_RS04725"
                     /old_locus_tag="DW860_04720"
     CDS             24652..26202
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392502.1"
                     /locus_tag="DW860_RS04725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04720"
                     /product="transposase"
                     /protein_id="WP_330422470.1"
                     /transl_table=11
                     /translation="MRQLKLPLEIEKLIDISDPVYTFCEVMDHIDLSRYFVEKGYKTGR
                     PRCDAQKLIKVILFAFMENGICSLREIEKLCRNDIRYMYLLDGMKTPSFATFGNLIRNE
                     LTDSIEQIFEDINSYIFAKDHVDLQHTYIDGTKIEANANRYTWVWKKSCVKNRQKVFDK
                     ISLLIDAMNLEVLGYLGIKFEKREAYAVDYVSELLTMYKETTGLDETSFVSGRGHRKSI
                     QQKQYEELHEYLERLKSYAYHIETCGEERNSYSKTDHDATFMRLKRDYMGNDQLLPAYN
                     LQAAICDEYIAVIDVKPYASDMECFVPLMEKFNRTYGHYPKYPVADAGYGSYNNYLYCE
                     EHGMEKYMKFTMYKKETTDKKYHENPYRAVNFAKDADGNLLCPNGRKFLFKRTQHVKYN
                     KYGRTEELYECESCEGCQHKQECCPRAHKNRTIRMNQELTAIHQEVLQNLESIHGALLR
                     MNRSIQSEGTFGVLKWDKAYKRLLRRGEKNVILELTLISCGFNLYKYHNKKQRQTKVA"
     gene            complement(26585..26755)
                     /locus_tag="DW860_RS04730"
                     /old_locus_tag="DW860_04725"
     CDS             complement(26585..26755)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="DW860_RS04730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04725"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_118404113.1"
                     /sec_met_domain="TIGR03731 (E-value: 2e-17, bitscore: 57.6,
                     seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDVTKTAAQGGIEPKYKSKSVCTPGCPTGILMTCPLK
                     TATCGCHITGK"
     CDS_motif       complement(26687..26755)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKFDDFDLDVTKTAAQGGIEPK"
                     /locus_tag="DW860_RS04730_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(26585..26686)
                     /prepeptide="core"
                     /locus_tag="DW860_RS04730_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="12.50"
                     /molecular_weight="3256.9"
                     /monoisotopic_mass="3254.6"
                     /core_sequence="YKSKSVCTPGCPTGILMTCPLKTATCGCHITGK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDVTKTAAQGGIEPK"
                     /leader_location="[26686:26755](-)"
                     /alternative_weights="3275.0"
                     /alternative_weights="3293.0"
                     /alternative_weights="3311.0"
     gene            complement(26779..26949)
                     /locus_tag="DW860_RS04735"
                     /old_locus_tag="DW860_04730"
     CDS             complement(26779..26949)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="DW860_RS04735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04730"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_118404113.1"
                     /sec_met_domain="TIGR03731 (E-value: 2e-17, bitscore: 57.6,
                     seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDVTKTAAQGGIEPKYKSKSVCTPGCPTGILMTCPLK
                     TATCGCHITGK"
     CDS_motif       complement(26881..26949)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKFDDFDLDVTKTAAQGGIEPK"
                     /locus_tag="DW860_RS04735_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(26779..26880)
                     /prepeptide="core"
                     /locus_tag="DW860_RS04735_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="12.50"
                     /molecular_weight="3256.9"
                     /monoisotopic_mass="3254.6"
                     /core_sequence="YKSKSVCTPGCPTGILMTCPLKTATCGCHITGK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDVTKTAAQGGIEPK"
                     /leader_location="[26880:26949](-)"
                     /alternative_weights="3275.0"
                     /alternative_weights="3293.0"
                     /alternative_weights="3311.0"
     gene            complement(26973..27143)
                     /locus_tag="DW860_RS04740"
                     /old_locus_tag="DW860_04735"
     CDS             complement(26973..27143)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="DW860_RS04740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04735"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_117640233.1"
                     /sec_met_domain="TIGR03731 (E-value: 6.6e-17, bitscore:
                     55.9, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKFDDFDLDVTKTAARGGIEPKYKSKSACTPGCPTGILMTCPLK
                     TATCGCHITGK"
     CDS_motif       complement(27075..27143)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MAKFDDFDLDVTKTAARGGIEPK"
                     /locus_tag="DW860_RS04740_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(26973..27074)
                     /prepeptide="core"
                     /locus_tag="DW860_RS04740_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="9.70"
                     /molecular_weight="3228.9"
                     /monoisotopic_mass="3226.6"
                     /core_sequence="YKSKSACTPGCPTGILMTCPLKTATCGCHITGK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAKFDDFDLDVTKTAARGGIEPK"
                     /leader_location="[27074:27143](-)"
                     /alternative_weights="3246.9"
                     /alternative_weights="3264.9"
                     /alternative_weights="3282.9"
     gene            complement(27168..27308)
                     /locus_tag="DW860_RS04745"
                     /old_locus_tag="DW860_04740"
     CDS             complement(27168..27308)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR03731"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR03731.1"
                     /locus_tag="DW860_RS04745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04740"
                     /product="gallidermin/nisin family lantibiotic"
                     /protein_id="WP_117640231.1"
                     /sec_met_domain="TIGR03731 (E-value: 9.6e-14, bitscore:
                     45.8, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKFEDFNFDVTKTVKPQSSKTPRITSKSLCTSSCETGFFKCVLT
                     K"
     gene            27603..27974
                     /locus_tag="DW860_RS17560"
                     /old_locus_tag="DW860_04745"
     CDS             27603..27974
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025677.4"
                     /locus_tag="DW860_RS17560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04745"
                     /product="transposase zinc-binding domain-containing
                     protein"
                     /protein_id="WP_243000704.1"
                     /transl_table=11
                     /translation="MLYTLHPRESVIENVNKMMHCGDSSYGGAMYHCPDCNEWKFVPFR
                     CHSRFCPTCGNMYSIDRTTSMSFKLLSCTHRHCVFTIPEQLRHFFLEDRSLLNCLFSSV
                     RSVILCMFHKMNAHTVVKQ"
     gene            28144..28332
                     /locus_tag="DW860_RS04755"
                     /old_locus_tag="DW860_04750"
     CDS             28144..28332
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004607984.1"
                     /locus_tag="DW860_RS04755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04750"
                     /product="hypothetical protein"
                     /protein_id="WP_117640229.1"
                     /transl_table=11
                     /translation="MKKTTTKDLAEKLRSQYIKNPPEGMSDHDIKLMSDNDLLDMDYFL
                     HEFDDDDDFGEEGFYLF"
     gene            complement(28463..29821)
                     /locus_tag="DW860_RS04760"
                     /old_locus_tag="DW860_04755"
     CDS             complement(28463..29821)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="DW860_RS04760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04755"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_118404115.1"
                     /transl_table=11
                     /translation="MGVKITKRQYSLKFFFIKFILSLIIGVGVSIALPLVLATLASNMG
                     YITVANYNEIQAEKTAKILATEKNLDYKNIPAGIKYLIISKEFDILNTNMSNGEQKDAL
                     RYANGKFEKTASGKQFILVTRDKEFCILQYYIGSHFTNMWLDIHMPSPDILINAGMILN
                     CLFVFSIMVFLFAKELRKELKPVMDATTKIEEQELEFNISSSRIIEFNDILKSIYNMKN
                     SLKKSLKTQWNIERQQKEQVSALAHDLKTPLTIIGGNADLLSETNINQEQEEYINHILE
                     SSKRMENYIAILIDLSKNTGEIPINRESISIGKFIDSIKGQMQSVVAMKKMNLIIAIMD
                     ESFGIEIDTVLMERAIINVLSNAVDHSPTHGEIIFNVTKDKGKCKISIIDSGPGFTPAA
                     LKYGLERFFMDDKSRNYQHHYGMGLYITNSIVTQHGGKVELKNKRGAEVDIII"
     gene            complement(29812..30477)
                     /locus_tag="DW860_RS04765"
                     /old_locus_tag="DW860_04760"
     CDS             complement(29812..30477)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008705326.1"
                     /locus_tag="DW860_RS04765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04760"
                     /product="response regulator transcription factor"
                     /protein_id="WP_117640225.1"
                     /transl_table=11
                     /translation="MIKILVIDDEEAILELVKRGLEKEGFAVDTLTSAKKVDVSKLRQY
                     NLLILDVMMPDIDGFTFCKKIRDMFNAPILFLTAKTLEDEVLYGLGIGGDDYITKPFRI
                     KELRARVKAHLRRESRENHDYLFSEDGNIKFDLSAKKLLVCEKEIPLTHSEYKICELLI
                     QNRGHVFSREQIYERVFGFYGESADNTIVVHVKNIRVKLSEAGVNPIQTVWGIGYKWE"
     gene            complement(30539..31375)
                     /locus_tag="DW860_RS04770"
                     /old_locus_tag="DW860_04765"
     CDS             complement(30539..31375)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033433.1"
                     /locus_tag="DW860_RS04770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_04765"
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="WP_117640223.1"
                     /transl_table=11
                     /translation="MKNSILIKRVILVFCMMSIIIIGSGCAAKKAVLENQGKTECYLDE
                     KDATKFIYNGQQYTILNNTVDKNSLGDWIGFIQKYVALDENYNILKKCDMGVNVVGDLS
                     DLIDHTDGTAYYVPYLNVYKTENEGDMNNLVVDVDNDFHKAILSENAKDGDLKIIFKNQ
                     NDTKDIENDLPQIDKEDVRNLTWEGKIYQITDQVVPNEKIGDYLCTLSGNITFDAETGR
                     EFTHDELNAIDIIPGELSNQKRETWIYDSVYTVIGKDKDSLAVEINYKCVYAILKD"
     misc_feature    complement(31672..31684)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.27"
                     /tool="antismash"
ORIGIN
        1 tgcgcatgtt tttgtataca cttaatatat atcacgcttt taaaaaataa aagacttgat
       61 ttgaattatt ttttatagta ttctataaaa cggtcaattt taaaaatcac gaaattgcag
      121 gctttacaac actttgtaac acgatatagg cctgtccgat aatccctctc atatctttta
      181 tccgaagtta tgtatgagga ttctgaaacg gtatagtatg gtgttgtgaa gttcaatcaa
      241 ctttcagcat ccgatacccc acgccaatgt gtgtttggat atattgtgga gagtttggtt
      301 ctttctcgat ttttttacga agtgttgcca taaacacacg aagggaagca atatcattat
      361 cccaactact tccccaaatg ctttgcgtaa ggaaagtatg ggtcagaact ttccctatat
      421 ttcttgtcaa caggcaaagc aacttatatt caataggtgt taaatgcaac tcttcttcat
      481 tcaaataagc acaacctgca gcataatcta cacgaagttt tccgtttaca aaaacaaccg
      541 cttcggcagg ggatactttt tgcatcatcg ataaccttct ttgcgtgact cgtagtctgg
      601 caagcagttc ctcaacagaa aatggctttg ttaaataatc atctgcgcca gcatccaacg
      661 catcaatttt atcggtatct tcactgcgag cactgattac gataattggc atatttgacc
      721 aagtacggat ttttttaata atctcaacac cgtctatatc aggaagtcct aaatcaagta
      781 aaacaatgtc aggattgtgt gaagatgttt ctaaaattgc cgattgacca tcgggtgccg
      841 tcagatatcg gtattcgtgc gtttttaagg ttgttgtaat taaatttctg acagatgtgt
      901 catcttctac aactaatatt agtgacttat tcatatactt tgacctcccc tgccggtaat
      961 gtaaatgtaa atactgttcc gtgcggcaga ttatctgaaa cagtaagttc tccgccgtgg
     1021 gcgttaataa tggacttgca caaagataat ccgagtccta aacttcggcg gctgtctgca
     1081 atttgatttg caccgctata gaacatgtcg aatatccgtg gctttatttc gtcagcaatt
     1141 ccgtttccgt catccgatat agatacgatt gcttgttttc cccgcttttc tgtccgaata
     1201 acaatatgag agtttttagg tgtatatttg atagcattat caacaatatt gatgattacc
     1261 tgaacaataa gctttgcatc catttttgca agaagaaatt cttctttgct ttcaacggaa
     1321 atatgatgtt cttcactctt tcggttaata tgatgtaacg cttctgtgat cacgtcatcc
     1381 atcaaatctt ccattatacg gagattcaac cgtccttctt caatccgggt tacagccagc
     1441 aagttttcta caaggttaat cagccacatg gaatcatcat aaatatccat gtacagctgc
     1501 ttttttgtat cattatcaaa ggaatcgccg ttggacaaaa gattgctggc attaccggaa
     1561 atggatgtca gcggtgtcct caaatcatgt gaaatagcac gcagcaggtt cgctcgcaac
     1621 tgttcatttt ttgcaagaat ggccgcctcc tgtttctcac gggcattttt ctcattttcc
     1681 aaagccaggg cacattctcc gagaatggat agtagaatac tgttttcaaa tggatcaaga
     1741 ggtatttccc ccatcacgat tccaataact ccatatacca tactgctgct gcgaacagca
     1801 aggtacaggc attttgcatt ggaaagcgtt cctgttgtag ctccggcacg tttattgttt
     1861 ttcaataccc agccggcaac ggccttttca ttttcggaaa tacacgattc caaattttct
     1921 tcagttacag aaaaaatatg cggcgtatcc aacacttctc catcagctaa ataaaaaacg
     1981 atatcttttc tcaagagttt aatgagctga tttgaagttg cagatacaat ttcattttta
     2041 tcttttgcct gttgcaatag ctggtttgta tcaaataaca ctttggtgcg gtaagcagat
     2101 tgtgccgcct gttttgcttg gtttttaatc cgtatagcaa gagaaccggt taaaaatgcc
     2161 gccaacaaca tgataataaa ggtaacagga taaccatgat catacgcctg caaggtaaat
     2221 tgaggttccg taaacaggaa attaaagacc aaaacactta caatcgagga aattaggctg
     2281 tatatctgat gtttcgtgat gacagcggtg acaagaacac ctaaaacaaa aacagtaatg
     2341 atatttgctt cgtcaaatcc aaatttctgg aaaatcattc cgactaaact ggataaaatc
     2401 agaatcgcag tagattttaa tgtatcagtg acagagaata cgatatgatt ctttttcctg
     2461 ccccctctta actgatacac tgtcgcatta gaaaccgtat ccggaataat atgcacatcc
     2521 aggttagggg cataatcaat caatttttct gtcagggtcg gtttgctgag caaatgccgt
     2581 tttgtagccg aattacgtcc aatcacaatc tttgacacac cggacaaacg agtaaattcc
     2641 gcaatctgaa acggaacatc ttctccgtaa actgtttcta tttttgcccc aagctgctca
     2701 gcaagacaaa tatttgaacg aaggcgtttt acattttcct cgctcatcac cgaaaaatct
     2761 ggggtttcta caaatagagc cgtaaactcc cctttaaaag cagaagccat ttttgcggcg
     2821 gtacggataa ttttcgcatt ggatggagaa gaagatagac atacaagaat atgttcgcct
     2881 gtgtgataat ctccatgatt ttttatgcga gtattttctg tgaggatatt cacccggtcc
     2941 gcacatcgcc gcagtgaaat ctcccggaga gctgtcaaat tttctattgt ataaaaattt
     3001 tctactgcct gtttttcctg tgtctgcctg tatacatttc ctgtattcaa acggttgatc
     3061 aaatcctgtg gttcaatatc tattaattca acctgatctg cattatcaaa aatagaatcc
     3121 gggatgcgtt cccgtacaac aatttccgta atggatgcaa ctgtatcaca aaggctttca
     3181 atatgctgaa cattgacagt cgtatagaca tcaatccctg cattcagaag ttccttaatg
     3241 tcctgatacc gttttgcatg acggcatcct tcggcattcg tatgcgcaag ttcatctaca
     3301 aggataagct gtggttttct tttcaacgcc atgccaatgt cgaattcgtc cagtatcata
     3361 ccattataaa aaacttctct tgtaggaaga acttctaagc cattcaaaag agctgctgtt
     3421 ttgggacgtg cgtggggttc tacataaccg gctaccacgt caattccctt ctgtttttcc
     3481 atatgagctg cttctaacat ggcgtaggtt ttacccacac cagctgcata tccgaaaaag
     3541 attttcaaat gtcctttatt acgtttttct tcatcagctt ggatttcctt taataactga
     3601 tccggattgt gtctgctttc actcatacgg ttatctcctt gtacaaaaac attatataga
     3661 ataatacgta aatttcagaa aagcatttta gcactgacat taaaatcgca taaagattat
     3721 accacctttt cttctttttt tccattcggg cgtgtagccg aaagcagaaa acgctccgaa
     3781 aaatcacgca atttttcgac aaatagaccc ttcatacaat taatgtcatt ttgccatatc
     3841 actctcgctg gtttctcaat cgtgttgatg ggatgtaccg caatgtctat agagcctaga
     3901 gtaatgacac tttgctttat ttgaaaggat aaggaacaat actcatcttt caaaatatcg
     3961 ttggaatttt ctatgataaa gccaaaatca agtttattat tttccagccc atttattatt
     4021 tcacttacag aaccgtagaa catgttcagc tcatagtttg ggtattcgct tgaaaattgt
     4081 tctaatagat ctgcaataga atctatgatt gcaggtgttt caaatccaat cctgagctta
     4141 gaatctgaaa taagtttttg agattgattt tccttgagaa atttatccag cttttccata
     4201 agaaaataac cataaataaa tgctaccaat accactataa gtaaaacaaa atctttcata
     4261 tcaccaactt ctttcaaaaa ttaaatatga aaacattttt gaatatgttt tttctccccg
     4321 agaacaagca tggtactatt ttttaacaac tgcgtatcgg aacttatttt caaattcata
     4381 atatcatttg ttttcagtgc cataatattg atgttatatt tttttcgtat attcaactga
     4441 ccgattgttt ttcctatcca ttctcccggt atagatattt caaagattgc atgttcttca
     4501 tctagttcta tgtaatcgag aatatgatca gcactataac ggatcgcaac ccaatcggca
     4561 agctgccttt caggataaac aatttcatct gcgccgtttc ttaaaagaaa ttttgcatga
     4621 acatcacgag cagcacgaga caccaccatt cttgcaccga gttccttcaa aagggacgtt
     4681 acttccaatg aattctgaaa atcatctccg attgccacaa tacaaacatc aaaattccca
     4741 acaccaagcg aacttaaaaa atcctcatta gtcgcatccc caatctgagc gttggttaca
     4801 aagggaagta cagcatcaac tcgggtatct tctttatcta ccgccatcac ctgatgatgc
     4861 aattcatcta attttatagc aatatgccgt ccgaatcttc ccagaccaat aagtaatatt
     4921 gatttcattt tttattctcc tttaacctac tgtgattttt tcctgaggat attttgaacc
     4981 attaggcttt ttttcagaaa tggtggcaaa aatcaaggtc aatccgccca ctctgccaaa
     5041 aaacatcaag caaatcaaga ttatatggga aacaagcccc aggtcaggag ttattcccag
     5101 cgataaccct accgtcccga ttgccgacgc cgtctcaaac aaagcaatca taagtggaat
     5161 atcttctgta ctgctaatta ccattcctcc gacaaggaat aaaacgatat acatcaaaaa
     5221 aatcgtagct gcatttctga taatgccatc cggaatttgt ctgccgaaaa aatgagtgtg
     5281 ttcctttttt ctaaatacag ataatgccga tgaaacgaga actgcaagag ttgtcgtttt
     5341 cataccacct gcagtggaac caggcgaacc accgatgagc atcagcataa tgataagcat
     5401 ttgcccaact tcactgagta aagtcaaatc tgccgtatta aatcctgcag ttctcggcgt
     5461 aacagattga aacaaggaaa tccacactct ttccataaga ggcacatttg aaaactcaaa
     5521 ataaaaaaag taaagagccg gtaagaatat caatagtcct gttaccataa aaatcacctt
     5581 gctttgcatt cggtattttt tgaaatgcca tttatgattc tttatatcct cccaggtgag
     5641 gaatccaata cctcctgcaa taatcagcat cataattaca agatttacaa tcggctgtac
     5701 agaataagag gtcaacgagg aaaaaggggt tcttataccg attagatcaa atcctgcatt
     5761 gcaaaaagca gaaatagaat ggaacagtga ataccatatt cctttccaaa acccaaagtc
     5821 cctgcaaaaa acaggggcta aaagaaccgc accaatgatt tcgataagaa tagtagtccg
     5881 aataataaat tgcgttctcc gcacaatacc acccactgtt ggagccgaaa ttgcctcttg
     5941 catggtactt cgctgcatca acccgatttt gcgtccggaa acaacagcaa tcgcaatagc
     6001 aatcgtaata attcccatac ctccgatctg aatcagcagt aaaataactc cttggccaaa
     6061 taaagaccag taggttgccg tatcattaac aaccagtccc gtcacacaaa ccgcagaagt
     6121 tgcggtaaac aaagcatcca aaaaggaggt acactgaccg ctttttgtag caatcggcag
     6181 catcaaaagc agacttccta agagaatcac ggataaaaac cctaaactaa tcacttgaaa
     6241 tgatgttata tgccgatgtc ttgacctgtt tttctgttgc ataactatgt ccccataatc
     6301 ttaatttctt ttatatcgcc tttattctat ctttattcgt attaaatggg cgtaagtaag
     6361 tttgttttga aattaagatt gtataaagat gagcagaagt ctgaaatctt ttgctcatct
     6421 tttgagagtg ctagttgttc tttgccattt tttattttct cctttgcttt gaataaaaga
     6481 aaaggacact catcttccag aagttctgaa aacaagcgtc ctttcggttt ttctctatgc
     6541 tattgaataa aaaatgttaa ttctgtccga atgtgtttcc tcataccaga tgcaatacta
     6601 ctgacacttc gatgccattc ataatctgct ttttcttacc ctgtttgcct gttggtgtga
     6661 aactcatata cctcgcaaag tgcctaaaat tcagcacttc tacgaattca cccgatgtag
     6721 acaacacacg acttccacat gtgttgtcac taacatagga acacacatcc tttacctcgt
     6781 ctacgatatg ggaacacatt tctttcactg tttctactgc ttttgatttc ttcccaaatc
     6841 gttcttttgc gtttccaatt tcatttttga atcctgtttt atatatgaaa ataattttat
     6901 agggatcttt ctctccattt tcatcgtaac caccgacaat aactttttcg atgatacttt
     6961 caaatattcc tctgtcaaat tcttctaata cttgattttt tgacaatgcc ttcttaaaat
     7021 ctgcaagtct tctttgtaag cttccctcat tgtcatattg ctgttccaac atactcagct
     7081 gtgattttgc ttcagacaat tgcttttcat atcccatatc tgtttcctca taaatgtctt
     7141 tagccacaac accttctaaa taattttcca gcaacttttt tctcttgtat tgaatattat
     7201 aaacgcttct attaagcttt tcaattttat cttctatcga atcttccaat aaagttttct
     7261 caactctctt aataaattcc tccaacacgt ctttatgatc catacataac atgcggtaag
     7321 attcaataaa agcatcctct ataacctgct ctggaattcc tttactgtct gggcaaaacc
     7381 ttttaccatg cttcgttgat tccacgcatt gccaaatagt ttttgtatat tttgagctgc
     7441 tatgccacct tcgccttgat aaattcgcac cacaaaatcc acactccaac atacagctaa
     7501 atgcatactg tctgctgaat ttttctcttt tcccaggggc aactcccttt ttacgtcctc
     7561 cattacgacg ttctcgtatt tcctgggctc ttgcaaaagt ttcctctgat ataattgctt
     7621 catgatggtt ctttatataa aacctatctt cttcaccaag attttccaac cttctctttg
     7681 atattggatc tactgtaaaa gtctttccta ataaaatatc tcctttatat ttttcattat
     7741 taataattcc catcacactg gaagaggtcc atggatttcc cttaatggtt gggattccct
     7801 gttcgtttaa ttcccttgca atcatcgtac ttccagctcc tgcaacatat ctatcaaata
     7861 tgtatcgaac tgtttccgca ccttcttcat taacagaaag cgatttagtc accacatcat
     7921 aatcataacc taagcatccc tgaaatccaa cgagttctcc tcgtttcatt ttcatcttta
     7981 agcctttttt tacatatgca gatgtatttt ccacctcttg ctgtgcaaca gaacttaaaa
     8041 tagtcagtaa aaattcccca tcctttaagg tattaatttt ttcaacctca aaatatactg
     8101 ctatattcct ttctcttagc attcttacat attttaatgt gtctaaagta tttcttgcaa
     8161 atcgtggaat actctttgca attaccatat caatatttcc tgaaaggcat tcctgaatca
     8221 gtaactgaaa ttcttcacgt ttatctgttt tcgttcctgt gatagcttta tctgcaaaga
     8281 ctccggcaaa tacccactgt ttattacttt taatcaaatc agtataatac ctgaccattg
     8341 aattatagct tttaatctga tcttcatcat cagtactaac acgacaatat gcggcaactc
     8401 ttaatctgtc aatccttctt ccattagaaa tatcttcatc ataactgttc gctttaatga
     8461 tttcaacttc catttcaccg gtcctttctt atgtattcct atcgtagtgt taatattatt
     8521 ctacaacgca actctgtact agtcaagcag taatattgga aattacacca taatcttttt
     8581 ttagtttttt ctctattaag cgatattcat tttcattgat aagttctaat gatctaagtt
     8641 gctttagcat ggatagctgc atactatatc ttaataattt tgtactgttc attttccctt
     8701 ccttatttat ttatagataa tcctgcaggc agccatcggg taatagcttc attggtattt
     8761 caccatcttt ccagaccggg cagctttccc ggaagtatca ttatcagaaa cagtatcttc
     8821 gccacaaaag tcccacttcc tgattacagc caaatattta tcgctcgtgc ctttacttca
     8881 atatcatttt gatatttctt cgtttacaac atttccactt tgcgtcacga tgtcgcaaag
     8941 ttataatgca gacagtcttg gcgtatttgc tatacagctc ctctgtttca tatgtcctgc
     9001 aggataaata ttaaattttc aaggtacaaa caacgctaaa tagctttttc agcagaaagg
     9061 gatgctttca aatgtttttt agcgaactat tttaaatcca ataattgttt ttatcaattt
     9121 tgtttccaga cgtctacgaa gtgtttcatc tacacaataa tgaacacagc catactcatc
     9181 atacattttt ctaaccgaca attttgcaat atatccttca taatgtttca gaattttatt
     9241 tatcgcctga atgtcaccct ccaatgctct ttcgattacc caaaacggta tcaatttttt
     9301 attatttacg cttttttctt ccgttttcac ctgcattttc ctccagcata atctttagta
     9361 tttcaagcga tcgtgtacga tgctcatgta ccgtacttct gacaaggttc agttttcttg
     9421 ctatatccgc atcattcatt tccatgaagt atgataaaag aataatgtcc ctttttctct
     9481 ctgtcagcgc agttaatgct tctgccaata gagcattttt tacctccaca tcataaccgc
     9541 ctgcccgaaa atagcttttt tccaattcat attcatcaaa tagagaaaga ctctccatct
     9601 cctgttcgga taattctgaa aacaaagttt catgttttct aagataggct aaatgtcttt
     9661 cataatccac agtttcgccc tttaatgcca atttgcattt tcgatcaaac tggtgcatta
     9721 ccgttttctc gtcataggaa gaagattgct ccatagagtt cacctccttc ccgaccatga
     9781 gatatgagca aaggtctttt tccctttcac ccttatcccg attgggaagc ccccattgtt
     9841 cgggtttaaa agaaaaactc tataaaaaag ttcttatgat atacaaaaaa cgtccttatg
     9901 gattgaaatc catcggacgt tttcatataa ataatctaat attcaaaaat aattttctcc
     9961 ctccattcca tataataaaa aaagcggaaa caatttttta tcatctccgc ttattcttgc
    10021 tcttttcaat tttatatttc aaaataccaa catactgaga gatcaaaatt ataaaggaag
    10081 tcagtgcaac taaggaaagt atgtctggta ttcctgcaag tgtacaacaa ccagcaaata
    10141 caataacagc acttaagact ttcatggtta cttttttaca gtgttctttt tcagtatcat
    10201 caagttctcg attaatgcac tctactggcg cagctttcaa tatcagtatc gcacttacta
    10261 atataagaat ccacgctgta cctaccgtaa acttatattt actgttaaaa tacattgcta
    10321 ttatctgtac agtgactgaa catataaaac atgatccaaa actgttaaga tgcacgccac
    10381 cggcataagt ccgtagcaac ataaaaatcc cagtaaatat tgcgaattcc ggaatcatat
    10441 gcatatatat tgctatactc aaacaagtta cgaaacagca tagcatctca agtccaatct
    10501 gaaagccata ttgatatact acatataatt ccggggaaac aacaccagtt tttataacat
    10561 actttgctat tttttctgaa agctgtttca tattaagatt gtttcatatt tttcagagct
    10621 tccggcattt tgggctgatg ataaatataa cagcacgcac tgtcggctga cattttgcca
    10681 agttttaatg acacacttgc cagcattttt gccgactgtt tttttacatc tttaagtttc
    10741 ataatagaag tcctccttca tttgttttct tacatcctac tataaaaaac ttatcctttt
    10801 tctttcttgt aaaaaaaacg agtattcatg taattttttc catatactat tgttcaaaaa
    10861 aacaatggcc acactgatcg ttgctttttt atccaccttt atattttttc aaataccaat
    10921 cccataaaat aatatcttgt atttttttct gatatttctc caagtcatct attgtttcta
    10981 tataatcata cacacctatt ttaagaactg aaaaaatgtc ctgcatactt ccattttcta
    11041 taacagcaag gatcggagtc aaatgcccta atcttccttt tacctttatt attggttgaa
    11101 gtatatcttt tctgatttta tcctcatcaa aatgcattat aacaacatcc gcaaacggat
    11161 atccatttgt ttccagacac tgataattgc cccatattaa ttcctgtttt ccttctgtta
    11221 cttgtttagt aatctcaaat aatttttcat catcgctaaa taataatatc ttctccacat
    11281 taagacctca tagccgcata attaatttat cattttattt taccatcatt tttaatagtc
    11341 tatatttttg ttgtaataat ttcgagagct tatgtaatta ttcctggttt ccgtataaca
    11401 atacccgaat cttaaactgc ccggacacag agtcatcaat tataatagtc ccacaatatt
    11461 ttgcgactgc ccggtaaaca gatgccagtc caacaccatg attttcagta tcagtttttg
    11521 ttgattttaa tcggtgatct tttgttttca gcaattttcc actataacta tttgttactg
    11581 aaagtaaaat attattctta tcatatttca ttttgatttc tatatatttc tttccatcca
    11641 ctttttgtgc tgcttctact gcattttcca ataagtttcc aagtatcaaa catatatctg
    11701 cgcctttaaa cggtagcatc ataggaatgc aaatatccgt tttaaaatct atttctttct
    11761 tctttgcggt tacataccaa tacccaatca gtgaatcaat gactatattt ccactgttag
    11821 aaatggcagc tatagccatt ccactttctt ccataatttc atttataaat ccaataatct
    11881 tttcatgttg cctgttttct gcataagcaa ggatggacac aagattattt ttcatattat
    11941 gtttagcatc acgtaattga agtattgaaa tttccctttc ctgctgatgc cgttcacata
    12001 attcaagctg ctgttcatat acagaagcca tacgtcttaa tcgtaaatca tcggctaatt
    12061 tcatataaat gtaaaatata agtatattca ttaccagcaa aataattact gtaattgccg
    12121 agttaatacg agtatgatta tcatttactg taaatccaag cataaataca ttgttcataa
    12181 tgtatatgct ccccatcgga atcaaaacga gcataatgct gtatcgaacc gacagttctt
    12241 taatctcatc atctgtgaat actttcttca gtgcaataat cactgcaaga aaaaatgatt
    12301 tagaaacaaa cgagccgata ggctgaatag aagcatattg ctcacaataa atcatcaata
    12361 cataattact cagggtttcc ataagcatcc agattgcatt aaatgtaatc acaaacacgc
    12421 acttattcca ccacataccc tcataagtga tcgtaactgc aaacaatgta acaattactg
    12481 taactgcaat atttacataa gcaggaagac taatgatagt cgatattcca aactgccaca
    12541 aaacaaattc cgtcaatcca gccacccata attttttact cttttttcga gcaaaaaata
    12601 tatcaaaata ataaaagaac agatatactg cataagcact cagcaatata tctgctccgt
    12661 aaggcaaagc cttatctatc cacataatat gtatcctcca tcgaacaata ctgctcgctg
    12721 ataagctttc ttctgtcttc actaatggaa atcttttttc cattgtccat tactacaaaa
    12781 tcataggatt gtccttttat atgcttataa tttacgagaa aagactgatg aacacgtaaa
    12841 aaagagattt tacatacctt cagactgttc tctatctcat ttaatttccc ataaaactca
    12901 aaagtttctt ctctagtcac aataaacacc ttccgtttac tgctctcaaa gtataaaata
    12961 tctcggatca ataccttatg attcatacgt tgataactat aacgaaagta aaaatctcca
    13021 ctatttatgt cttcataagc tgccataaaa catgtttcca tttgtttttc acttactggc
    13081 tttaccagaa actgaaatgg tcgaactgaa aaagattctt tcatataatt ttcatgactg
    13141 gtaacataaa taatcaaaac atttttatca tatttcctga ttcttttagc tgttgaaatc
    13201 ccatcctcgt tgttcatctc tatgtctaaa taaatgatat cgtatccatc ccctgctaca
    13261 accgaatctg ccaggctttc accattccag aatacttcta tatctacatc agcaaaattt
    13321 cttttcgcta ttttttgaat catcatttct atctgccctg ttgtttgaat atcatcatca
    13381 caaatcgcta tattcagcat tcacatcaac tctcttctat cagtttattg tccttttttc
    13441 gcttttctcc caccttcttt accgtctgca taattgacca tatcatttct ttgtcatacg
    13501 aatctaaatc cttatatatc tcaattaagt cataatactc atctaatgtt tcattcattt
    13561 tcatctgtct ctgcaaatcc ctttttacat ctgaaactcc caaaagataa tcagtagtta
    13621 cattgaaata cgttgctatt ttcttgagaa tatccacctt tatcaatgtg acatccctct
    13681 catatttact aagcatttgc tgagttattc ctaattctgc tgcaagaatt tcctgtataa
    13741 gtcctcgttt ctccctgagc tgtttgattc tactctccat aattgattac ctcataatta
    13801 tattgtaatt ctatgctacc ctaattcatg cgtcgtaata caaataatga gagtaatcaa
    13861 ttacgtcatt atattttata cagagatagt aggattattg aatgggaaat cggtaattgt
    13921 cagtaaaaat ttattttttt catacaggtt atcagatttt gtttctgtac cagacatgag
    13981 aatcaataga taatcttaac ttcctgataa tttaactctc gattgcccaa aacccccatg
    14041 aatagtagat ttgcgagtat tttatatgtt aattctcgag aggtaattaa ttctcttatc
    14101 attaacgata caatacgcaa aatccgcata aataagccat tctttggaaa cgagagttaa
    14161 ttttacaaga agttaagaga taacaatcca aataacacct aacacatctt aatcactttt
    14221 ttcaaacatg cgacaatcag caatcgcctc gtaaatatta taatttcaac ataccacata
    14281 aaatacatcc atatatccaa atgtaatttc ttcgattgtt catgtcatta ttttgctttc
    14341 gacagtaggt tttacttata aattattcta tgaacgtttt cttgttatta taagcgtcaa
    14401 agcaacactt gcctttggga actaggtttg agtaataatt ctccatatat tggcatttta
    14461 taaaagtcat ctgataggat ttctcccagc tatttagtaa atatcaaatt ttttgcctct
    14521 gataaatcat tccttggaaa caagagcatg cgttcacata caaacgaagg cgttgaagga
    14581 cggattttca cacaatttat cgcattgata atccgaaaca caatttatac tgcattacat
    14641 gaaaaaaatg aaaaacttga gagtaaacag aattatatga cagttccagc agtaatcaag
    14701 gaacttgaga agattgaaat gacacgacag acggataatg tataccggtt ggatcatgct
    14761 gtaacagcaa agcagaaaaa aatcttaaag gcttttggga tgaatgaagg aaatattact
    14821 tatcgggtcg gagagatcag taatacactt aagaaatcaa acattcagaa agaatggcgg
    14881 taaatatggc acgtgagatt aacgcagaac tactggatac taaaattgaa aaagcacagc
    14941 aagatctggc gaaagcaaaa catctatatg atgctgtggc agcaacatta aaagatctgt
    15001 tagataagcg ggattcactt cgtcagaaaa agctattgga tgctatagca caaagcggac
    15061 ggagctatga agaaatcaag cagtacctac acagtaaatc tgaagcggtg tgatcaaatg
    15121 ttaacggaat actattttgc agtcaggtat ggagatatca ttattctgct ctatcatgaa
    15181 gtgtatgact gaagtacaga ttcagggtgc caataacatg taaatttcca gcctaagatg
    15241 ctttagggct atttcaggct ggaaattaag gttatcctta tatatttcta ttgaaaaact
    15301 ggctaaaatt aatgcatcat gaaaaagatg aggataaaaa tatcgtgagg ataaccctgt
    15361 ggcaataaaa attttttcaa atccgacagc atcattaagc atgtagaagc cccccaacct
    15421 tatttagaag ttcttctgta gctttatttg atatttcaat tgaaacagat cctcttcgaa
    15481 taacaacatc cggtttaaaa ggactggcag atgaacttgt gtgatcagtc attttgattt
    15541 caacgaaatc tgtagttgtt ggaactgaat tttctttaac agctggcgtc aaggtgttct
    15601 ctaatgtaga gaggtatgct tcttctcgga gaattcgttg ccagtaaaaa aatgatttat
    15661 ctgaaatacc atcctctcgg caccaagtcg ttttggacat tccactagta agacattctt
    15721 tgatgatatt tgtccattgt tcacatcgaa ctttatgagt tattttatcc atgagattat
    15781 tcctcctcta aaaaatctta gatttttcaa agtgattatc tcatgaaaac tagcgaaaat
    15841 cttggtactt actattcacc gtttactcct atcctatctt tttatgccaa taaaaaagct
    15901 ttcttccata aattatcgct cttcttctct ccttcaagaa gagagagaca tacgccggtc
    15961 gttccttcta acagtccaca tacatcatat ggttttattt tctccatttt attgtcaagc
    16021 tccatatttt taaatccata tatataatcc ggattataaa aatcagttat tttattcttc
    16081 aagagttcct tttctaaaga aaaaaactcc ttttgtaaca acatttctac cgaatttaat
    16141 acttggtata gaccagcata tccatgacaa aatgtaggtg aaaaaatacc tttaatattg
    16201 ttcattgtaa gtctcaaatt ttctattccg taatcaatca aaaactgatt gtctaaagca
    16261 ttaccggccg atacaattgc ataacatatt cccggatttc cataacacca tgcatctcgc
    16321 cgaataatat tttcatcggt taattttttg tttactactt catcaaaatc tatctgccct
    16381 ttccagaaat cacgttcacc atcattcaac ttaaaatcaa aaaggaattt aattattttt
    16441 attatagctt cttcttgtcc atccacaata atcccattag ccatcatatc tgaaagaatt
    16501 gttaatggtc ctgcaatacc atgagataaa ctagtattga aattgccttt tggataaaga
    16561 tcttgttcta attcactaaa ttggttttga accggaatat accaacccgg aacaacttga
    16621 ccttgaatct caatgtcttt agtcaaattt acaagaatct ccaatcctct tgtgatgaca
    16681 ttataatact ttctttgatt tctataaatt cctagataac tcaaaacacc gctcagccct
    16741 tcaattacat cgtaatagag tgaatgtgtc ccttcctctt ttactatatt gctgtatgac
    16801 tcttcaaacc gatttaggat atagtcattc aacgtattta gtaatttgtt atagtttaaa
    16861 aaatcattgg aaacactagc tactgataga gccacaccgg cagcacctga aaacatagac
    16921 agactttgaa atcccttttt atttagctct tctaccatta gtgataaata attatgagca
    16981 aatcgtcccc atttgtcttc ttttggacaa cactccatta attttccgta caataaacaa
    17041 atccccggaa gaccatgact caaagtaagt ggtgaaaatg cttcaaattc tattccttcc
    17101 caagtccgtt ggttttcttt tctccccatt atttttaaca ttctttcgta atcacttaaa
    17161 tttgtagcaa tgttcttggt catagttaaa atatcgcatt ccattttcct acatgtcctc
    17221 tctttcatat gattccgctt tatatagctt ttgatatgtc atacagtttc gcagtagctc
    17281 atcatgtttg cctattccaa caattttgcc ctgatccata actataattt tatctgccat
    17341 ttttgctgca ttaaggcgat gagaaataaa aacgccaatt ttatcttttg ataattcaaa
    17401 aaatttttca aaaacttctc tttcagatac tgtatcaagt gcagcatttg gctcatctaa
    17461 aatataaaaa gatgcatctc taaaataaac tcttcctaat gctattttct gccactgccc
    17521 ttgagacaat tgacatccat cttcaaacca atttcctagc tgcaaatcca aattataact
    17581 tccattatcc gtttgcaaaa acttagtttg taacttatga agcatttgaa ccattttttc
    17641 atcattgttt agattttgaa tatctccaaa gccgatattt tcccttaaac taagctcata
    17701 ttttacaaaa tcttgaaata aaacagacat ctttgatcta taacttctga tatccaaatc
    17761 tattaacgat ctaccattta tcaatatttc gccttcttcg atgttataga gcccggctaa
    17821 aattttcaaa aaagtgcttt ttcctgatcc gttaggacct acaagagcaa ccttttcgcc
    17881 ttgtaccaat gtcagattaa ttttgtccaa tacttttgtt tttccattat atgaaaatga
    17941 aagttcttta atatctattt tattaattgg ttccttcatc actatttttt ctgaactatc
    18001 ttcttttaca cagtaattca aaaattgaaa aagcatatcc atatacaatg tactactata
    18061 tactgtataa atatttgaca ttattgcctg agaatttgtt tgtactaacc ctacactcct
    18121 aatataactc ataacattac caacaagaat ctcaccaaca tatgctgaca ttatagccac
    18181 tcctataatg attgcactca caatttgtat agataactca tatagaatat tgaataacgt
    18241 ttttcttttc aggatggagg tgttttggcg aatgaaaaga gcactaatac tccaatactt
    18301 tttaagaaaa tagtctttca aatccaataa ggatatctct ttgaatgaaa aatcatgcgt
    18361 cagtaaataa gttagatacc atgtttttcg ttcgtcttta gctctattcc acattatttc
    18421 aaattcctgt tgccctattt ttaagtaata tagcattgat ataataggaa ctacgagtaa
    18481 tagcatagat atatatggat tccatgcaaa taataaaaag gctgaagata gcattgttac
    18541 aaccgaagta ataattccta taattgcaat cataatttga tatggcttat atgccacttc
    18601 tccggtgatt ttttcaattt tatcatacat ggcaggcgtc tcaaaatctt ttaatgtcag
    18661 ttttgtacac ttatccataa tcaagtaatt caatttgtac tgaagaacat attgaaattt
    18721 gctttcaata taatcttttg cttctccaag aatacttcct aaaaatgaaa cgataatata
    18781 aatcgtaaat agaatgatgg tatatcgtaa tggtgagctt ttcttaacta ttgagttaat
    18841 taattcctgt gataatacca atgttattac aggaaaagct cccgctatca tacttagcat
    18901 tactataagt gtaaatcctt ttttatcaac ttttctaatt atagttatag ttttaggtat
    18961 ctgctttaaa gccctccaaa cttctttaaa ccctactttc ttattattca tgatcttcat
    19021 tcctcttcat tatgtatcgc ttagcataca ttatactttc agaaaatgcc attaattttc
    19081 tctccagttc acgatccgtt ccaattattc tattacaatg tagatgaatt acgcttgcaa
    19141 ctataccatt tttaaacaac ggatcctggt ttatattgtt gatttcatcc ctatatttat
    19201 taagtacaac tgttctcata tttaataaat tatataggaa agttccttct tcattactta
    19261 ataattcttt ccaatcattc tcacacccgc ataatgaaac taatctttgc tttttctttt
    19321 taaattccga cataaagtct gatgtatgat aatttattgc cagaaaattc atttgttctt
    19381 caaagttttc ataaaatccc tgaatataca taatgattga gataattgct atatcctcct
    19441 gatccatagc taatacccct aatcgcttca ttctgaggat actttcaaca ataaagctgt
    19501 cgataaaaaa tacttgctct gcaatatcca taagatgcac accaccatac cgttcaatct
    19561 ctctatcata tatagaaatt tttaaatcac caattatacc atcatccaat aattggtgct
    19621 gccatttaat aattagcgga tatatctgta acaatacttc ttgtgttcct tttatccgta
    19681 gccgtacatg tggtttagga tctacataac gcataaagaa ataatctaca tcatatttct
    19741 ttttaagctc ttcacagaaa tccatgatat caaaggcaat caattcatct tcacgattac
    19801 tattgcaata taggttaaaa tataaccaat tttcaaaagg taattctaaa tgtttctttc
    19861 tctcaataat cactttctcc gccggataaa cattctgtag ttccttttct tttctgaaaa
    19921 gaggaactac aatttcagtt gtatgacccc cttcaccact ataagtaata ttttcaccag
    19981 tttcagctct ttcaagaatc agatcacgac taccatgttt cttaaattca tcaaaaataa
    20041 tcctaattga caattctttt tttaagtcca gctttattct gttatcagct tctgttaaat
    20101 aaatatcatc cggtatgttt ttatctttta taagttgtaa aaacttgcat ttaaattcct
    20161 caaaattttt cttttctaat cgcatctcac taaggtttaa cttccatttt tcattttcaa
    20221 ttacaatatc ctcaaacttt atggctggta catggcggaa ctctgagaat atatatgtcc
    20281 aaggaaattc tgaccaagat ctcttccctt catgtgatat gtcctgtaaa aaccttaata
    20341 tattaggatt tagcatcgga ttgtacatat tattagattc aaagacgact aatttctttg
    20401 ttttataatc tcttgcgtaa aacaactcat taaaaacccc tatggaaata tcttttatat
    20461 tgataacatc agtagttcct ttatctgctg ctgtaaaaat aaccgttttc ttttctctaa
    20521 atgtgcgggt tctaacaata tttccatttc tggccggtgc aggaagaaac ccaatctcac
    20581 acatttcaat attatcatca cgtaatcttc tttcttcctt attaatatct tccaacatat
    20641 ccgcaaattc atcggagatt gtggagaatc gaccaaaagt tttaccagct acaagcgaac
    20701 cacaattagg acctaaacaa agatttaatt catcatttct cttcttaagt tggaaataca
    20761 gctctaacga tatggggact tcatccgttt taatttctct ttttagaatc ccctcaattt
    20821 cgtcctgttc taaagtgata gatgttttat tggtaatagc agattcatat ttattcagca
    20881 aataattttt taaccttaaa ttgtaattag gtttagtaga atcttcctca aaaaaatcat
    20941 tttggggatt aagatatgaa gtcggtgctc ctattccaat atttgaatct aacatttcta
    21001 ataatggtac ttctctgtca actccatact tttcaataaa cttattccta tattcatcta
    21061 aataagtgtg actctcattc ttatcattgc ttatataaac aaaaaagctt gccaacctat
    21121 taatcttatt tgcaactgtt gattttattt caaactcagc attttcaatt actgtatcca
    21181 cttgtaagta agacgaacaa gaatacagta gcttcatttt agatactatt ttatcgtaca
    21241 gagttatccc ttcacctact ggtaaattca tgtaggaggt acacatcttg cttatctcta
    21301 taatatttcc tgcttcttca aaaagtgcac tttctcttaa tcgctcaatt acatatgcta
    21361 tttgatttct tgaatttaaa gacggcctaa ggtctgaaat tagtatttct tttgaaataa
    21421 gctcatttaa ataaaaagta actttttcat ttggcacatt aggatactct tcttcaatga
    21481 ttctagcaat ctggttatat tctttgaatt cctggcatga ctcataaata atttcaaaga
    21541 ccctagtcgc tcttacacta atttcttcta tttccttttc agtagaatat aaaagaatag
    21601 ctctatttcc tttaatataa catgcatcat ttattttaaa cctaagtctt tgtgacttaa
    21661 tcttttctaa ctgagatata aatccaaaaa gccattctga atcaatattg actttctttt
    21721 gatatttagc ccctgatacg tcaaaagtat cactatctcc gaattttccc agaccgacac
    21781 ctgaaaaaag cccaaatggt gtagttctat ttttgctcct aatcaaatat ttcataattg
    21841 aattttggaa gtttactaac ttcttctcag ataatttctc tggattttta atgtacaaat
    21901 ccatcatatc aactaatgca ggacttgcta tactgacttt ttcacggaac tttgcatcta
    21961 aacacgcgtt ttttatctcc tcttccgtaa agtcaagttt tctctctaca tcatttggta
    22021 tacgaaacat aaacttttga gtgttatagt ataaattttt catttctacc tcctaatctg
    22081 ttataagtca actataaagt gaaattatca aaaaaatatc aagatttttt gaacatattc
    22141 ctaaaatatg atatacttaa gaaaaagata aaggcaccct ttccatgaaa acaaaagaag
    22201 aacttctact ttctgttaag gaagacattg aagcatttgg aaaagacaag ttagtgtacg
    22261 cacatatgtc attgcaaaac gaaggaacca tcttatatgg ctactcatat actcccgaag
    22321 gaaaatttat agacgaagca tcattagaag agttacttat tatattagaa agtgacacgg
    22381 atatgtaaaa gtaagaaaag agggatgacc aaatttacgg tttccccctt ttcctctatg
    22441 tgatcggtaa ttttatgctt accacagcac catgctcttt agaattgtat agttccaatt
    22501 ccccttcaca agattgaata actttattcg cataagctag gccaatacca tagtgaattg
    22561 aatttctatt attatttgaa gtaaaaaata atttagttcc attctcaaga acctgactac
    22621 taaactctcc tttttcatta catatggtaa atatataaga atcatctttt tgtccaataa
    22681 aacacattat tttgtcacca tataccttat attctattgc gttatcaata atgttaaaaa
    22741 ttgccctttc taaagatatg tagtctatct taatagtgcc cctcactttt tcaacattaa
    22801 atttaattat ttcttcagat ccgctgatat actctttaat ctcagagact attttatgag
    22861 aaaaactgtt gcagggcata ctttcctttt cgtgaaaatc aattctatca gctttcacat
    22921 atttaattaa taaattaacg tattcctcca tctttcccac agctccccaa atactttgca
    22981 gatgagataa actgtactca tcagatgaat aacattttaa aagctctgta tttccactga
    23041 taattgtaag cggtattttt atatcatgag ccaatgctgc tatttcctca tttttttcat
    23101 tttctatctt ccaggtttga tacaatgact cttttaatgc atccctcatc ttaattaatg
    23161 ctgtaataat attcgaaaat tcttttatct tactttcttc gtaagtgaaa tccagattct
    23221 gtttttctat ttccagcgta attttctcta tcttttcaaa attatttttc cagatgctaa
    23281 ctaagtgtaa tgtcataata tacacatata gtaaaaacac taataccatt gtaatatatg
    23341 acaaattgtc atagtctata taattgaaaa ttctattgtc agagttaaaa cgtgctttaa
    23401 tattatactt tataacgcaa tattcttctg ttctagcaat tactgagtaa acataattcc
    23461 cttgaagatt actttctttc cctaataata tttttttagt tacttctata tctgatttat
    23521 tcatagtccc acgttcataa ttataatcta aatcaaagat tgaatactta cttccatatg
    23581 gtaaatcatt atctgttatc tgttgtatat catctaaacg ctttctattc tcttccaaaa
    23641 tagtttcgct ataatttgct ggaattatca ctccgcattc cacaaatata ttagttaaag
    23701 ccaaccaaca gattattata accacgattc ccacaaacaa ttttatcaag tacagtaata
    23761 actgtctctt catcgttatt attttatatc ccatttataa cctatccccc aaatagtttt
    23821 tattggatca agaccaagtg ttttgaactt ttttctgatt gagtaaataa actctgttat
    23881 agtccttaat tgtgcattgg catctaagtc atataagtat tcatatagct cattttttga
    23941 aaaaatcttt ccgctattct gaacaagaat tttacatatg cgaaactcat ttttcgttaa
    24001 taaaatttca ccattatcta attttattga gtttgaatct tgattaaaca ccaatccatt
    24061 gattaaaatc ccgttactct catttttcaa acttcttctt aatgcaactt tcactctggc
    24121 tactaactct ctgatactaa aaggtttggt aatataatca tctgctccac tcatcaggcc
    24181 tttcactttt gctccttcac tagacttagc agataaaaaa atcaccggac atgttattat
    24241 gttttttatt ctctccaaaa tttcataacc atctaaaaac ggtaacataa tatccaataa
    24301 tattaagtca aacccttcaa attcaccaat attagtattg tcaacatagc ttcttgtttc
    24361 cactatataa tgttcatttt tcaaaacttc ttgtactaat tctaaaatct tttcgtcatc
    24421 gtcaatcaca agtatctttt ccattatctg ctcctttatg tttttactaa ctaataataa
    24481 caaaaattag taattaatca cccaacatgt aaaaaatact catttgctcg taaaaaaagg
    24541 ggctgtaaaa aaactcccct gacagaaaaa tcgcccagac cgtgaggtct gagcgatttt
    24601 ttggtataat taattatgct actaaataac aataccaatg gtaattatac tatgcgtcag
    24661 ctgaaattac cattagaaat cgaaaaattg atcgatattt ccgatccggt atacactttt
    24721 tgtgaggtta tggatcacat tgacctatcc agatattttg tagagaaagg ctataaaaca
    24781 ggtcgcccaa gatgtgatgc tcaaaaactc attaaagtaa tactttttgc ctttatggaa
    24841 aacggcatct gctccttacg agaaatagaa aagctctgcc gtaatgacat tcgttacatg
    24901 tatcttcttg atggcatgaa aacaccttct tttgctacat ttggaaactt aatccgaaac
    24961 gaactaaccg attctatcga gcagatattt gaagacatta attcatatat ttttgccaaa
    25021 gatcacgtgg atctgcagca tacatacatt gacgggacaa aaattgaggc aaatgccaat
    25081 cgatatacct gggtatggaa aaaatcgtgt gtgaaaaacc ggcagaaagt ctttgacaag
    25141 atttcactct tgattgatgc tatgaatctg gaagtacttg gatatctcgg aataaaattt
    25201 gaaaagcgtg aagcgtacgc ggttgactat gtctctgaat tacttacgat gtacaaagaa
    25261 acaactggac tggatgaaac ttctttcgtt tccggacgtg gtcatagaaa aagcattcaa
    25321 caaaaacaat acgaagaatt gcatgaatat ctggaacgtt tgaaatccta tgcatatcat
    25381 atcgagacct gtggagaaga aagaaacagt tattccaaaa cagatcatga tgcaactttc
    25441 atgcgtttaa agcgtgatta catgggaaac gatcagctac ttccggcata caacctacag
    25501 gcagccatct gtgatgaata catagctgta atcgacgtaa aaccatatgc atccgatatg
    25561 gaatgctttg tgcctttgat ggaaaaattc aatcgcacat atggtcacta tccgaaatat
    25621 ccggttgctg atgccggata cggttcttac aataattatc tttattgtga agaacacggc
    25681 atggaaaaat acatgaaatt taccatgtac aaaaaagaaa cgacggacaa aaagtatcat
    25741 gagaatccgt atcgtgctgt aaactttgca aaagatgcag atggaaatct cttatgccca
    25801 aacggtcgaa aattcctctt caagagaaca cagcatgtga aatataataa atatggaaga
    25861 acggaagaat tatacgaatg tgaatcttgt gaagggtgtc agcataaaca agaatgttgt
    25921 ccgagagcac acaaaaaccg aacgatccga atgaatcagg aattaactgc tatccatcag
    25981 gaagtgctgc aaaatcttga atccatacat ggtgctctct tgagaatgaa ccgaagtatt
    26041 caatcggagg gaacttttgg tgtattaaag tgggataaag cgtataaaag attattgcga
    26101 agaggcgaga aaaatgtaat tctcgagctt acactgattt catgtggatt caatctttat
    26161 aaatatcaca acaaaaagca acgacagacg aaagttgcat aaaacttaag cgggcgtgat
    26221 tagccgagct ttattaaatg caccattttt tatacccaaa gatgcagact tgcttagaaa
    26281 tagaaaagtt aatacaaaga aacgccaaaa ccgacatttg ccggaattgg cgtttcttat
    26341 attagggact tattttacag cccctttttt atgtatctac actaaaacag atttattgac
    26401 cctttaattt acatgtgcat gtaagttgag tttttggtgg acaaagaaat cctgttaggc
    26461 aattgggtgt acaaaaagag tgttaacttg taatactcgc aggtataata tctcttctta
    26521 cttttttttg ataatatcca aatcaaaatc atcaaatttt gccattacgc ttcacttcca
    26581 atctttattt acctgtgata tggcatccgc atgttgctgt cttaagtggg catgtcataa
    26641 ggattcctgt cgggcatcct ggggtacaca ctgatttgct cttatacttc ggctcgatcc
    26701 caccctgtgc tgctgtcttt gttacatcca aatcgaaatc atcaaatttt gccatctttt
    26761 tttcctccgt attctttatt atttacctgt gatatggcat ccgcatgttg ctgtcttaag
    26821 tgggcatgtc ataaggattc ctgtcgggca tcctggggta cacactgatt tgctcttata
    26881 cttcggctcg atcccacctt gtgctgctgt ctttgttaca tccaaatcga aatcatcaaa
    26941 ttttgccatc tttttttcct ccgtattctt tattatttac ctgtgatatg gcatccgcat
    27001 gttgctgtct taagtgggca tgtcataagg attcctgtcg ggcatcctgg ggtacacgct
    27061 gatttgctct tatacttcgg ctcgatcccg ccccgtgctg ctgtctttgt tacatccaaa
    27121 tcgaaatcat caaattttgc catctttctt tctccttata ggtttaatta cttagtaagc
    27181 acacatttaa agaatccagt ttcacaactt gatgtacata aagacttgct tgttattctt
    27241 ggagtcttgc tactctgtgg ttttacagtc ttcgtaacat caaaattaaa atcttcaaat
    27301 tttcccattt ggtgcctcct ttcttcttga taaattagtt atacaatata aaaatcagca
    27361 aaatatcaaa atcgctccta aatttaatat atttttttac aatgtcgttt ctagctatat
    27421 tcctaagtct tattaacaga ggacgcagaa aataatatac tctaaacaaa aaataggctt
    27481 cgcctattca actcccctcc ccctcattct tgaggggatt aagggttttc ttttttctct
    27541 ttttcattca taataaactt atgaacacat tacaaaaaat ctttttagaa cactacgagg
    27601 aaatgctcta taccctgcat cctcgcgaat ccgttattga aaatgtaaat aaaatgatgc
    27661 attgtggcga ttcttcttat ggcggtgcca tgtaccactg tcctgactgc aacgaatgga
    27721 aattcgttcc ttttcgttgt catagtcgct tttgccctac ctgtggaaac atgtattcca
    27781 ttgaccgcac tacctctatg tcttttaaac ttctttcctg cactcaccga cattgtgttt
    27841 tcacaatccc tgaacaacta cgccattttt tccttgaaga ccgctcttta cttaactgtc
    27901 tcttttcttc tgttcgcagc gttattctgt gcatgttcca taaaatgaat gcccacactg
    27961 tggtaaaaca atgatgcttc ttgaaattta ttacaatcat cgccccgtct ccttgcaaga
    28021 tctatatgag aaaaccatga aaaagcatag gattcgtcct tctgcccgta gtaaatttct
    28081 tttatctccg tccacttcgt gatacaatca agttatcatg tgttagaaac ggaggtttta
    28141 cttttgaaaa aaactacgac taaagatctt gcagagaagc ttcgctcaca gtatataaaa
    28201 aatcctcctg aaggtatgag tgaccatgat atcaaactca tgagtgacaa tgaccttttg
    28261 gatatggact attttcttca tgaatttgat gatgatgacg attttggtga agaaggattt
    28321 tatcttttct aacaatcgtc tatttcctat gcctcttttt tatgaggcat ttttttactt
    28381 ctgctttaaa caaaggactt tcctaatata taaaaaaact ctggtgtatt ccaccagagc
    28441 taacctgaac tatgaatttt tcctatataa taatatctac ttctgctcct cttttatttt
    28501 ttaattctac ttttccacca tgctgtgtca caatagaatt tgtaatatat aaccccattc
    28561 cataatggtg ttgataattt ctactcttat catccataaa aaatctttct aaaccatatt
    28621 ttaatgctgc cggcgtaaaa ccaggacctg aatctataat actaatctta cattttcctt
    28681 tatccttcgt cacgttaaaa ataatctccc catgtgtagg agaatgatct acggcatttg
    28741 ataaaacatt tataatcgcc ctttccatta atactgtatc aatctctatc ccaaaagatt
    28801 catccataat tgcaattatt aaattcattt ttttcattgc aactacagac tgcatctgtc
    28861 cttttatact atcaataaac tttccaatag atatgctttc tctatttatc ggaatctcac
    28921 cagtattctt ggatagatca atcaatatag caatgtaatt ttccatgcgt ttagaactct
    28981 ctaaaatatg gttaatatac tcttcttgct cctgattaat atttgtttca gataataaat
    29041 cagcattacc acctatgatc gtcaacggtg tcttcaaatc gtgtgctaat gccgaaactt
    29101 gttctttctg ctgacgctct atattccatt gcgttttcaa agactttttt aaactatttt
    29161 tcatattata aatagatttt aatatatcat taaattctat tatcctcgat gatgaaatat
    29221 taaattccag ctcctgctct tctatttttg tagtcgcatc cattactggc ttcaactctt
    29281 ttcttagttc ttttgcaaac aaaaagacca taatactaaa tacaaataaa caatttaaaa
    29341 tcattcctgc attaatcaaa atatctggag atggcatatg tatatctaac cacatattgg
    29401 tgaaatgaga accaatataa tattgtaaaa tacagaattc tttatctctt gtaactaaaa
    29461 taaattgttt acctgatgct gttttctcaa acttaccatt tgcatatctc aatgcgtctt
    29521 tttgttcccc gttgctcata ttagtattta agatatcgaa ttctttgcta attattaagt
    29581 attttatccc tgctggaata ttcttatagt caagattttt ttctgttgct aaaatttttg
    29641 ccgttttctc agcctgtatc tcattataat ttgcaacagt tatatatccc atattacttg
    29701 caagtgttgc caagaccagc ggtaaggcaa tactcactcc aactcctata atcaatgaca
    29761 atataaactt tataaaaaaa aactttagag aatactgcct ttttgttatt tttactccca
    29821 tttatatcct atcccccaca ctgtctgtat aggattcaca ccagcttcac ttagtttcac
    29881 tcgtatattt ttaacatgaa caactattgt attatctgct gattctccat aaaatccaaa
    29941 aactcgttca tatatttgct ctctggaaaa aacgtgtcct ctattctgta tcagcaattc
    30001 acatatttta tattcgctat gtgtcaaagg aatttccttt tcacaaacca atagcttttt
    30061 tgctgacaaa tcaaacttaa tatttccatc ttctgaaaat aaataatcgt gattttctct
    30121 ggactctcgc cttaagtgtg cttttacacg agctcttaac tccttaatcc ggaagggttt
    30181 cgtaatataa tcgtctcccc caatacctaa accatataat acttcgtctt ccagtgtttt
    30241 agctgtcaga aataaaattg gtgcattgaa catgtcacgg atttttttgc aaaatgtgaa
    30301 accatcaata tccggcatca taacatccaa aatcaacaaa ttatattgcc gcagtttact
    30361 aacatccacc ttttttgcag aagtcaaagt gtcaacagca aatccctcct tttctagtcc
    30421 acgtttgaca agctcaagta ttgcctcttc atcatctata actagaattt taatcaagat
    30481 atcctctcct tttaaaattt ttatttgtta gatattatag tcacaagttt gacccatact
    30541 aatcttttaa tatagcatac acacatttat aattaatttc aactgccaaa ctatccttat
    30601 cctttccaat aacggtgtat accgaatcat atatccaagt ctcccgtttt tggtttgaca
    30661 gttcgcccgg aattatatca atagcattta actcatcatg tgtaaattcc ctgcctgttt
    30721 ctgcatcaaa agtaatattt ccggataaag tacatagata atcgcctatt ttttcatttg
    30781 gtacaacttg atctgtaatt tgatatattt taccttccca agtcaaattt ctcacatctt
    30841 ctttatcaat ttgtggtaaa tcattttcta tatctttggt gtcattttga tttttaaaaa
    30901 ttatctttaa atcaccatct ttcgcatttt ctgatagaat tgctttatgg aaatcgttat
    30961 ctacatctac aactaaatta ttcatatccc cctcattttc tgtcttatat acattcaaat
    31021 atggcacata atatgcggta ccatctgtat gatctattaa gtcgcttaaa tctcctacta
    31081 cgttgactcc catatcacat ttttttagta tgttataatt ttcatcaagt gcaacatact
    31141 tttgaataaa tccaatccaa tcacctaatg aattcttatc cactgtatta tttaatattg
    31201 tgtattgttg tccattatat ataaatttcg ttgcatcttt ctcgtctaaa taacattctg
    31261 ttttaccttg gttttctaaa actgcctttt tagcagcaca acctgaacca atgattatta
    31321 tagacatcat acaaaatacc agaatcaccc tttttattaa tatactattc ttcataattt
    31381 tttcttcctt cccatttctc aaaccatata caaaacacca acaataacac aaatgttata
    31441 atgataactt taaatataat attgggttga agagtagaga gttgagtgtt aaattgcaaa
    31501 atttcttgtc tacacatatt tactgcccac gcccaaggaa tatattccca actaataact
    31561 aacttcaacg gaagattgct aaacaaaata acaataaggc tttccaacac ccctgttata
    31621 actgaagctc caagccctga tttcagggat aaccaaaaat ggattatata agttacaatg
    31681 ttacctaaaa ttatataaac ataactatac aatactgtat taagaacaga aatactaagc
    31741 tcttgatcca caactgctac tgaaaataaa attggtaaaa agagaattac aatggctact
    31801 gcacctattc ctaagaatag aattaacttt gcaataatta atttactctt actctccata
    31861 cctacaaaaa gtgcctgaaa atgcccttct tcttctaagt ttatacctag actaacagca
    31921 atagaaattg caagagggaa aaatgctgat gttgcctgta aaattagatt cagtctttgt
    31981 gttatacttt gttgtcctga atataagtga aaatacattg caaataatac ccctcctaga
    32041 agcggtacaa ttatgtgcaa caa
//
