LOCUS       NZ_QSHK01000001        21663 bp    DNA     linear   CON 28-FEB-2024
DEFINITION  Dorea formicigenerans strain AM37-5 AM37-5.Scaf1, whole genome
            shotgun sequence.
ACCESSION   NZ_QSHK01000001
VERSION     NZ_QSHK01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Dorea formicigenerans
  ORGANISM  Dorea formicigenerans
            Bacteria; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae;
            Dorea.
REFERENCE   1  (bases 1 to 741683)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     A genome reference for cultivated species of the human gut
            microbiota
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 741683)
  AUTHORS   Zou,Y., Xue,W. and Luo,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (02-AUG-2018) BGI-CNGB, BGI, No. 11, Beishan IZ., Yantian
            Dist., Shenzhen, Guangdong 518083, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 100x
            Sequencing Technology             :: Illumina Hiseq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 02/28/2024 19:12:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,338
            CDSs (total)                      :: 3,277
            Genes (coding)                    :: 3,188
            CDSs (with protein)               :: 3,188
            Genes (RNA)                       :: 61
            rRNAs                             :: 1, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (16S)
            tRNAs                             :: 53
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 12 of 89
            Pseudo Genes (incomplete)         :: 75 of 89
            Pseudo Genes (internal stop)      :: 11 of 89
            Pseudo Genes (multiple problems)  :: 9 of 89
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:18:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 592795
            Orig. end                         :: 614458
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            QSHK01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21663
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="2"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     cand_cluster    1..21663
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21663
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11663](-)"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11663)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     misc_feature    387..400
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.07"
                     /tool="antismash"
     gene            complement(706..2178)
                     /gene="hemZ"
                     /locus_tag="DW860_RS02865"
                     /old_locus_tag="DW860_02860"
     CDS             complement(706..2178)
                     /EC_number="1.3.98.3"
                     /GO_function="GO:0051989 - coproporphyrinogen dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hemZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331580.1"
                     /locus_tag="DW860_RS02865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02860"
                     /product="coproporphyrinogen dehydrogenase HemZ"
                     /protein_id="WP_118358299.1"
                     /sec_met_domain="PF04055 (E-value: 5.4e-25, bitscore: 84.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRVICNQETFVYNAYHMVKAFYPSETVMSSVDEKASNYVTVEFA
                     EDGTDGQKEAMIEIADRQTNDMPAEKSAMKKYLDRMLYKKLSEQSGRTLAWGILMGVRP
                     TKIAMRKLEEGMTQETFVPWFQKENLVSEEKAHLAWQIAGREKKLLDQLDYENGYSLYV
                     GIPFCPTVCSYCSFSSGALGDWEHRVEDYLAALMKELEAIAKMSEGRKADTIYMGGGTP
                     TTLNANQLDRLLTCIDRHFVREGLLEFTVEAGRPDSITKEKLQVLRNHGINRISINPQS
                     MQQKTLDTIGRKHTVEQVYEAFHMARKLGFDNINMDIIAGLPGETPEDMEDTLKQIALL
                     GPDNLTVHSLAIKRAAKMGQEEREGKRLTIIQDEIGTMVEMAGNKARQMGLFPYYLYRQ
                     KNIAGNFENVGYAKVDKAGIYNILIMEEKQSIIAAGAGASTKIVLKEPVINPESKKKKK
                     TSLIRQENVKAIDAYISRVDEMIERKGEWLWR"
     gene            complement(2181..2810)
                     /locus_tag="DW860_RS02870"
                     /old_locus_tag="DW860_02865"
     CDS             complement(2181..2810)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331581.1"
                     /locus_tag="DW860_RS02870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02865"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_005337742.1"
                     /transl_table=11
                     /translation="MKIEKFSLGILGANCYLLINEETKDTVVVDPGGHSKKFTAYIEEE
                     KLNLVAILLTHGHFDHIMGIDSILENWNIPVYVEEEDLPIMTDPELNLSSSYTNGYSFD
                     GAKPLKDGQKLELAGETIEVIHTPGHTMGGCCYYLPVEHAVFSGDTLFQRSVGRTDFPN
                     SSQDAIVRSVRERLFALPDDTIVYPGHMGETKIEYEKLHNPYVQEG"
     gene            complement(2827..5172)
                     /locus_tag="DW860_RS02875"
                     /old_locus_tag="DW860_02870"
     CDS             complement(2827..5172)
                     /EC_number="2.7.6.5"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0015970 - guanosine tetraphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248621.1"
                     /locus_tag="DW860_RS02875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02870"
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="WP_117494742.1"
                     /transl_table=11
                     /translation="MSENKTTYESLDGKIAPEALLKDTRGKLQMVDGHGIKQEADYDDP
                     DKLYGMLIARIQKYHPSADVTQIEKAYNLAKKAHGDQKRKSGEPYIIHPLWVAIILADL
                     EMDKETIIAALLHDVVEDTRIGEDYIKEEFGEEVALLVDGVTKLGRVAYSADKLELQAE
                     NLRKMFLAMAKDIRVIIIKLADRLHNMRTLQFMTPAKQQEKARETMDIYAPIAGRLGIS
                     KIKTELDDLSLKYLKPDVFFDLVNQINARKTEREEFVQQIVDEVSMHMKNAGIKADVNG
                     RVKHFFSIYKKMVNQDKTVDQIYDLFAVRIIVDSVKDCYAALGIIHEIYTPIPGRFKDY
                     IAMPKPNMYQSLHTTLMSSIGQPFEIQIRTQEMHKTAEYGIAAHWKYKESGGSKKGVMA
                     EEEKMSWLRQILEWQRDMSDNKEFLSLIKGDLDLFADDVYCFTPQGDVKTLPTGSTPID
                     FAYSIHSAVGNKMVGARVNGKLVPIDYRIQNGDRIEILTSQNSKGPSRDWLNVVKSTQA
                     KNKINQWFKKEFKESNIIKGKEMVASYCKAKSLNLSNLLQPKYEEIVQRKYGFKDWDSV
                     LAAIGHGGLKEGQVVNRLAEEYGKDHKQELTDEIVLEKVAEAAKNKVHIAKSKSGIVVK
                     GIDDVAVRFSRCCNPVPGDEIVGFVTRGRGLSIHRTDCVNMIHLTEAERARLIPAEWEG
                     NVAEETGGQYLAEIKMYARDQQGLLMSISKVFTEMEMDVKSLNIRTSKQGTATIEAGFI
                     VHGREELAKVIGKLRQIDDVIDIERTTG"
     gene            complement(5219..5743)
                     /locus_tag="DW860_RS02880"
                     /old_locus_tag="DW860_02875"
     CDS             complement(5219..5743)
                     /EC_number="2.4.2.7"
                     /GO_function="GO:0003999 - adenine
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006168 - adenine salvage [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006427080.1"
                     /locus_tag="DW860_RS02880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02875"
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="WP_040015335.1"
                     /transl_table=11
                     /translation="MKPIEDYVVSIPDFPEPGIIFRDVTSVLQDAEGLHLAIDLMQEKL
                     EGLDFDVVVGPESRGFIFGVPIAYNLKKPFIPIRKKGKLPRETVSAEYELEYGTATIEM
                     HKDAIKPGQRVVIIDDLIATGGTNEAMIHLIEGLGGKVVKTVFLMELAGLHGRDRLQGY
                     DIDSVIVYPGK"
     misc_feature    5808..5821
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.91"
                     /tool="antismash"
     gene            complement(5824..7539)
                     /gene="recJ"
                     /locus_tag="DW860_RS02885"
                     /old_locus_tag="DW860_02880"
     CDS             complement(5824..7539)
                     /GO_function="GO:0008297 - single-stranded DNA
                     exodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recJ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440042.1"
                     /locus_tag="DW860_RS02885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02880"
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="WP_118358300.1"
                     /transl_table=11
                     /translation="MERWVLLRKGADFEAISKKFHISPRLASLIRNRDVIGDEAINQYL
                     NGTIAELYDGMQMKGMPQAVEILTEKIRDREKIRVIGDYDCDGINATYILLEGLEKLGA
                     KVDSDIPDRIKDGYGLNQHLIDRAHADGIDTIITCDNGIAAAKEIEYGKALGMSIIVTD
                     HHEVPYKENEAGRRYILPPADAVVDPRQEGCEYPFKGLCGAAVAYKLVEAICEANGQDV
                     ADLDYLLENVAIATVADVMDLTEENRILVKQGLEMLKRTSNLGLRALIQCIGLEGKKIQ
                     AYHIGFILAPCLNASGKLDTAKRALALLRAKTEREADMLAGDLKALNESRRDMTDRVVD
                     EAMAKVEQTDIRGDKVLVIYLPDCHESLAGLVAGRVRENYYRPVFVLTDSEDGVKGSGR
                     SIESYSMYEELTGCGDLLTKFGGHPMAAGLSLDKENVEKFKRRLNDQCTLSEEELTEKV
                     VIDMELPFTAITEQFIEELEYLEPFGKGNTKPVFAARGVAMQHVKIIGKNKNVAKATAI
                     DAAGNRMEAICFHDAQEFAKQCERNNGKMSITFYPGINEFRGERQIQIVITHYR"
     gene            complement(7704..9947)
                     /gene="secD"
                     /locus_tag="DW860_RS02890"
                     /old_locus_tag="DW860_02885"
     CDS             complement(7704..9947)
                     /GO_component="GO:0031522 - cell envelope Sec protein
                     transport complex [Evidence IEA]"
                     /GO_function="GO:0015450 - protein-transporting ATPase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043952 - protein transport by the Sec
                     complex [Evidence IEA]"
                     /codon_start=1
                     /gene="secD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337749.1"
                     /locus_tag="DW860_RS02890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02885"
                     /product="protein translocase subunit SecD"
                     /protein_id="WP_117494744.1"
                     /transl_table=11
                     /translation="MKKSRGILSLIVAAALIVLLGFTTIVGFGKGHTGSMKNIKLGLDL
                     AGGVSITYQVKDDNPSDEEMSDTIYKLQKRVEQYSTEASVYQEGSDRINIEIPGVTDAN
                     EILDELGQPGSLYFIAQTGSDGSANYSQVNSTGDASKDYQLNKTIEELQADGSIVLSGN
                     DVKSAQAQTTEDQLTKNKQNVVSLTFTKDGTTKFADATTKALAASQSIGIYYDGAFVSV
                     PNVQAAITNGQAQISGNMTYEEADALASTIRIGGLKLELEELRSNVVGAQLGEQAVATS
                     LKAGAIGLAIVFVFMCCVYLLPGLASGLALLIYTGLVLVILNAFEVTLTLPGIAGIILG
                     IGMAVDANVIIFARVREEMVRGRSVKNSLKIGFQKALSAILDGNITTLIAAAVLWFKGS
                     GTVKGFAQTLAIGIIASMFTALVITRLIVNAFYAVGLRSEKLYYRPKKEREPIDFLSKK
                     KVFFTISLVLIAAGVITIGVNAGRGKGAFAYSLEFQGGTSTNVTFDKDYSIDEIDKEIV
                     PVVEKVTGDNNVQTQKVAGTNQVIIKTVTLDLDKREALNKAMVDNFGVDESKITAENIS
                     STVSNEMRRDAVIAVVIATICMLLYIWFRFKDIRFATSAVLALLHDVLVVVGFYAIARI
                     SVGNTFIACMLTIVGYSINATIVIFDRIREEMRGKTKSSDVAAVVNKSITQTLTRSIYT
                     SLTTFIMVAVLYVMGVSSIKEFALPLMVGVVCGAYSSVCITGALWYVMKRFKK"
     gene            complement(10001..11395)
                     /gene="scfB"
                     /locus_tag="DW860_RS02895"
                     /old_locus_tag="DW860_02890"
     CDS             complement(10001..11395)
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="scfB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331595.1"
                     /locus_tag="DW860_RS02895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02890"
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="WP_005331595.1"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 5.5e-31,
                     bitscore: 102.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PTHR43273 (E-value: 9.4e-78, bitscore:
                     257.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2e-15, bitscore: 52.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.8e-14, bitscore: 49.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.7e-18, bitscore:
                     61.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIHQYKNNGYNIVLDVYSGAVHVVDDLCYDVIAVLNEPDEEPTAE
                     ILKSDLTWENLKKRLGDTYSEEDLRDALDDVIELTEDGKLFTKDEFEYLVPIVKKRKTV
                     VKALCLHIAHDCNLACRYCFAEEGEYHGRRALMSYEVGKKALDFLIANSGSRRNLEVDF
                     FGGEPLMNWQVVKDLVAYGREQEKLHDKNFRFTVTTNGVLLNDEIQEFVNKEMDNVVLS
                     LDGRKEINDKMRPFRNGKGSYDLIVPKFQKLAESRNQEKYYIRGTFTRNNLDFSNDILH
                     FADLGFKQMSIEPVVGDESDPYAIREEDIPQIKEEYDKLAKIMIEREKEGKGFNFFHFM
                     IDLEGGPCVMKRMSGCGSGTEYLSVTPWGDLYPCHQFVGQEEFLMGNVDDGIVKPEIAD
                     DFRSCSVYSKEKCKNCFAKFYCSGGCMANSYNFHGTIHDCYDVGCEMQRKRVECAIMIK
                     AALADA"
     aSDomain        complement(11063..11395)
                     /aSDomain="Ranthipeptide_rSAM_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing rSAM protein in a
                     ranthipeptide/SCIFF cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DW860_RS02895_Ranthipeptide_rSAM_RRE.
                     1"
                     /evalue="2.20E-32"
                     /identifier="RREFam024.1"
                     /label="DW860_RS02895"
                     /locus_tag="DW860_RS02895"
                     /protein_end="111"
                     /protein_start="0"
                     /score="102.2"
                     /tool="antismash"
                     /translation="MIHQYKNNGYNIVLDVYSGAVHVVDDLCYDVIAVLNEPDEEPTAE
                     ILKSDLTWENLKKRLGDTYSEEDLRDALDDVIELTEDGKLFTKDEFEYLVPIVKKRKTV
                     VKALCLH"
     gene            complement(11520..11663)
                     /gene="scfA"
                     /locus_tag="DW860_RS02900"
                     /old_locus_tag="DW860_02895"
     CDS             complement(11520..11663)
                     /codon_start=1
                     /gene="scfA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004605085.1"
                     /locus_tag="DW860_RS02900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02895"
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="WP_005331596.1"
                     /sec_met_domain="TIGR03973 (E-value: 5.2e-26, bitscore:
                     85.7, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 4.4e-26, bitscore: 86.0,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKHVKTLNTQTLNKTVKKGGCGECQTSCQSACKTSCTVGNQTCEQ
                     SK"
     misc_feature    complement(11884..11894)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.79"
                     /tool="antismash"
     gene            11889..12911
                     /gene="gap"
                     /locus_tag="DW860_RS02905"
                     /old_locus_tag="DW860_02900"
     CDS             11889..12911
                     /GO_process="GO:0006094 - gluconeogenesis [Evidence IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /GO_process="GO:0019682 - glyceraldehyde-3-phosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gap"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331598.1"
                     /locus_tag="DW860_RS02905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02900"
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="WP_118358301.1"
                     /transl_table=11
                     /translation="MAISIGINGFGRIGRVALRIAISRPETFKLCGINARNADLDYMVY
                     MIRYDSTFGRFQGELGTYEHGLIINGQKIPVFTEGDAASIPWGSCGAEYIIDATGAFCT
                     AKKASAHLQGGAKKVIISAPAKDEETPTFIMGINHTGYSKDMSVVSNASCTTNCLAPIC
                     KVLEDNYGIEYGLMSTIHAATAKQKVVDSRSLKDWRTGRSAFGNLIPSTTGAAKAISLV
                     IPSLKDKMSGISYRVPTTDVSIVDLNVALKESASYEDICKKVKEASMTYLSGILDYVDD
                     EVVSSDFIGDPHASIFDARQGIQVNSHFFKVICFYDNEWGYTSQIFRLIKYMDQVDHNS
                     "
     gene            complement(13116..13487)
                     /locus_tag="DW860_RS02910"
                     /old_locus_tag="DW860_02905"
     CDS             complement(13116..13487)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331600.1"
                     /locus_tag="DW860_RS02910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02905"
                     /product="TIGR04086 family membrane protein"
                     /protein_id="WP_117613174.1"
                     /transl_table=11
                     /translation="MENMQKNIKVIWWIKSLLASYIVTGILLLVLTFFMYKFELNEKIV
                     SAAIVGIYVVSTLIGGVIIGKLTKSKRYLWGMVLGILYFVLLLLITLGVYRTLNGDSVS
                     IVTSLILCAGGGMTGGMIS"
     gene            complement(13557..14102)
                     /gene="spoVT"
                     /locus_tag="DW860_RS02915"
                     /old_locus_tag="DW860_02910"
     CDS             complement(13557..14102)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0030436 - asexual sporulation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="spoVT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331603.1"
                     /locus_tag="DW860_RS02915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02910"
                     /product="stage V sporulation protein T"
                     /protein_id="WP_005331603.1"
                     /transl_table=11
                     /translation="MKATGIVRRIDDLGRVVIPKEIRRTLRIREGDPLEIFTDREGEII
                     LKKYSPIGELAAFAGMYADSLAKEAGCLVCICDMDQVVAASGNGRKEVQEKYISKVLQG
                     ELEERNSILAKVDEKKYIRVFREQEKDYVWESITPIICEGDVVGAVILLSSDEKEKFTK
                     LEQKLGACAAGFLGKQME"
     gene            14371..15690
                     /locus_tag="DW860_RS02920"
                     /old_locus_tag="DW860_02915"
     CDS             14371..15690
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015520253.1"
                     /locus_tag="DW860_RS02920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02915"
                     /product="ATP-binding protein"
                     /protein_id="WP_117494748.1"
                     /transl_table=11
                     /translation="MIDTHKLKKRDLYLNKIIAFQDTEPVKVVTGIRRCGKSSLLKLMV
                     LHLKESGITDEQILEMNFESHAFKNMNSDSFYEYVKQHIVPNKRMYLFFDEVQRVPNWE
                     DAVNSFRVDFNCDIYVTGSNAYMLSSEYATYLSGRCVEIKMLPLSFSEFLTFHGFEVRE
                     IKSSLGGIRKQAFDKNDERYELRDVFDAYMRFGGMPGIADIGLDQEKALMLLEGIYSTV
                     IMRDILERENRKGQSRITDPVLLKKIIMFLADNIGSNISVSSIGNTLMNEGLLDNGKRK
                     GTPSVHTVQSYINALLESYFFYEIKRFDIKGKEFLRTLGKYYIVDIGLRNYLLGFRNRD
                     SGHALENIVYFELLRRGYDVSIGKIDNSEVDFIATKADNKIYVQVTESMTSEDVRKREL
                     SPLQKISDNYEKIILSLNPGMDSSYNGIKSINLIDWLISE"
     gene            complement(15796..16539)
                     /locus_tag="DW860_RS02925"
                     /old_locus_tag="DW860_02920"
     CDS             complement(15796..16539)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019542.4"
                     /locus_tag="DW860_RS02925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02920"
                     /product="hypothetical protein"
                     /protein_id="WP_118358302.1"
                     /transl_table=11
                     /translation="MAKSTRGYCKYCGKEYTRTGMLKHLQSCKKRMEVCENSKKMSAYY
                     ELMLYGTYNKDYWLIIQIKENATLECLDQFIRDIWVECCGHLSAFDIEGVRYEHIPDND
                     FLWGKPAEDMSHKLKEVLEVGMEIGYEYDFGSTTELTIKVVDFYKAPEQKENVTILSRN
                     NPIQFTCSVCGKNPAVWIDPIKMYNEDPFWCEECLEKYENGELDEEIEVEESGYLLPVT
                     NSPRMGVCGYEGSDFYPNQFEPDDM"
     misc_feature    complement(16540..16554)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     gene            complement(16660..17355)
                     /locus_tag="DW860_RS02930"
                     /old_locus_tag="DW860_02925"
     CDS             complement(16660..17355)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337755.1"
                     /locus_tag="DW860_RS02930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02925"
                     /product="sigma-70 domain-containing protein"
                     /protein_id="WP_118358303.1"
                     /transl_table=11
                     /translation="MADRAQFQKKLGELLAVAASQNNKMTSQEVQAFFQDDNLTDEQMN
                     LVHEFLMSQKVEVIGYTGTIENTEQAEQEEKDTLSQQEKDYVAEYLIDIEKMAKQTEEE
                     VKLAYYLPKVVEEAVKLHMPGIFIGDVIQEGNVSLMLYLGENKKATEAEVLEQVRAGIR
                     VMLESHTEEKRRDKKMVERVNDLDETIKSMKEEYGRKVSVDEVAERMGITEDTVEDILK
                     LAGEEVKDE"
     gene            complement(17483..18364)
                     /locus_tag="DW860_RS02935"
                     /old_locus_tag="DW860_02930"
     CDS             complement(17483..18364)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005331605.1"
                     /locus_tag="DW860_RS02935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02930"
                     /product="radical SAM protein"
                     /protein_id="WP_118358304.1"
                     /sec_met_domain="Fer4_12 (E-value: 5.4e-07, bitscore: 25.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.6e-15, bitscore: 53.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLCPRQCQIKREEGKRGFCGESDLVRLSRAALHMWEEPCISGTNG
                     SGAVFFSGCTLRCVYCQNYHIANSEVGKTVSVERLSEIFLELQEQGANNINLVTPTHFV
                     PQIIAALDQARKKGFNLPIVYNTSGYEKVETLRGLNGYVDVYLPDFKYLDPEHAKKYSG
                     AEDYPEVAKAALEEMVRQTGNPVFNDAGIMTKGVIVRHLLLPGCLRDARRIVKYLYETY
                     GDQIYMSLMNQYTPLDTLNREKYPELAKKVTKKAYDVLVDYAIDLGVEQAFIQEGETAK
                     ESFIPDFSYEGV"
     gene            complement(18376..19521)
                     /gene="glgD"
                     /locus_tag="DW860_RS02940"
                     /old_locus_tag="DW860_02935"
     CDS             complement(18376..19521)
                     /EC_number="2.7.7.27"
                     /GO_function="GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glgD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337757.1"
                     /locus_tag="DW860_RS02940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02935"
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="WP_022279790.1"
                     /transl_table=11
                     /translation="MINANADAMGIIFPNNYDKFVPELVSERLMASIPFASRYRMIDFL
                     LSSMVGCGIDKIEVLVRENYHSLVDHLGGGREWDLSRKNGGLSIFPPFAQKSIGSMGGG
                     RVEALANILPVLKKQKEKYVIMADTNIAANFDFNALIAQHVKTDADITFAYTKEELPQE
                     LTGAKDASKGLYYTLKLDGDKVEDIYINKQEQGVQNFSMNIYIANREWLIDTINAAFMR
                     GAISLERDILIPHLDTYKVMAYEHKGYVARITGLKSYFDENMKLLDDKNLEELFTGNPI
                     YTKIRDDNPTRYIGNAKASNVMVADGCVIEGEVENSILFRGVKIAKGAKVKNCVLMQDT
                     IVGEGTKLEYIISDKNVKITDGKELKGDEAFPVFVAKGQVV"
     gene            complement(19518..20723)
                     /locus_tag="DW860_RS02945"
                     /old_locus_tag="DW860_02940"
     CDS             complement(19518..20723)
                     /EC_number="2.7.7.27"
                     /GO_function="GO:0008878 - glucose-1-phosphate
                     adenylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0005978 - glycogen biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337758.1"
                     /locus_tag="DW860_RS02945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02940"
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="WP_118358305.1"
                     /transl_table=11
                     /translation="MGKEMIAMLLAGGQGSRLYALTQKLAKPAVPFGGKYRIIDFPLSN
                     CVNSGIDTVGILTQYQPLELNEYIGNGQPWNLDRIYGGVHVLPPYQKASGSDWYKGTAN
                     AIYQNISFIERYDPEYVIILSGDQICKQDYSDFLRFHKEKNAEFSVAVMEVPWEEAPRF
                     GLMVTDDDDRITEFQEKPKNPKSNLASMGIYIFNWDILKQYLIEDEADPESENDFGNNI
                     IPNLLRDDRKMYAYHFNGYWKDVGTIPSLWEANMEVLDPEHSGINLFDEDWKIYSRNSG
                     MPGHKICAGASVENSMITDGCKIAGSVKHSILFAGVKVEAGAVVEDAVVMGRTTIKAGA
                     SVKHCIVAENVVIGENAVVGAMPTEDEQGVATIGPDVCVGTGAKIGPNAMISEDVKDGE
                     EK"
     misc_feature    20851..20868
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: strong, score: 21.55"
                     /tool="antismash"
     gene            20987..21433
                     /locus_tag="DW860_RS02950"
                     /old_locus_tag="DW860_02945"
     CDS             20987..21433
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337759.1"
                     /locus_tag="DW860_RS02950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DW860_02945"
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="WP_005331608.1"
                     /transl_table=11
                     /translation="MSKIDEIRSAMVAAMKAGEKEKKETLSMLLAALKNKQIDKRADLT
                     EEEEIQVIMKEIKQTKETLEMTPADRTDIIEECNRRLTVLEAYAPKMMGEDEIKAIIEG
                     VLSELGIENPTGKDKGNIMKHLMPKVKGKADGKLVNDLVSTYFK"
ORIGIN
        1 cagaagcaac ttcatcaaaa agagaaaggt aggtcttaac actttcactg gtatatccca
       61 tctcaatcag ttctgcctcg acaccttccg gtcctatctt atccatctta tccagaacaa
      121 tgaagacttc atcatagtct tcctctttaa aaccactgta agcagccata gatttcaata
      181 tattacggtc attaatacat acagtaaaat tcttaaagtc cagtttccca agcatcgccg
      241 ttgtggcaag gatcagctcg atttcggcga gattggaagc ctctcctaat atatcgatat
      301 cacactgcac aaactggcgg aaacgtcctt tctgcgggcg gtctgctctc catacacttc
      361 caatctgaag tgctttaaaa ggagacggca gctcatttgc atgattagaa taatatcttg
      421 caagcggaac tgtcaggtca taccgaagtc ctccatccac aagatcattt tcctcttttg
      481 cctcgttaat ttttaacttt tctccacgtt tcaaaatctt gaagatcagt ttttcgttat
      541 ctcccccctg cttactgcac aggttctcga tatgctcaac acatggagtt tccatagatt
      601 ggaatccaaa tgttttatag gtgtctttaa tcaggccgat caggtaatcc cggatttcca
      661 tctctgccgg cattacatct ttcataccgg ttactggttt cttctttaac gccatagcca
      721 ttctcctttt cgttctatca tctcgtccac ccggctgatg taagcatcga ttgcttttac
      781 attctcctgc cggatcagac tggttttttt cttctttttg ctttcaggat ttatgacagg
      841 ttctttcagt acgatttttg tagacgcacc tgcacctgct gcaataatgg attgcttttc
      901 ctccataatt agtatattgt atattcctgc tttgtcaacc tttgcatagc ccacattttc
      961 aaaatttccg gcaatattct tctgacgata cagataatac ggaaaaagtc ccatctggcg
     1021 ggctttattt cctgccatct ctaccatcgt acctatttca tcttgtatga tcgttaatcg
     1081 tttcccttct ctctcttcct ggcccatttt agctgcacgt ttgattgcaa gggaatgtac
     1141 cgtcagatta tcaggtccaa gtaacgcaat ctgttttaga gtgtcctcca tatcctccgg
     1201 tgtctctccc ggaagtcctg caataatatc catattgata ttatcaaatc ccagctttct
     1261 cgccatatga aatgcttcat acacttgttc tacagtatgc ttacgcccaa ttgtatccaa
     1321 ggtcttctgc tgcatgcttt gaggattgat agaaattcga ttaataccgt gatttcgaag
     1381 cacctgaagt ttctctttcg taatactgtc cggtcgtcca gcttccaccg taaactccag
     1441 aagtccttcc cttacaaaat gtctatcaat gcatgtaagc agccggtcta actgattcgc
     1501 attcaaagtt gtcggtgttc caccgcccat gtaaatggtg tcagcttttc ttccttcaga
     1561 cattttcgca attgcttcca attccttcat aagtgcagcc agatagtctt ctacccgatg
     1621 ttcccagtca cctaatgcac cagaactaaa cgaacagtaa ctgcaaaccg ttgggcagaa
     1681 cgggattccc acataaagac tatagccatt ttcataatcc aactgatcca gaagcttttt
     1741 ttctctccct gcaatctgcc atgcaagatg tgctttttct tcactcacca gattttcctt
     1801 ctggaaccat ggaacaaacg tctcctgtgt cataccttct tccagttttc tcatagcaat
     1861 tttagtcggt cgtactccca tcaggattcc ccatgcaaga gttctgccac tttgctctga
     1921 caactttttg tataacatcc ggtcgagata ttttttcatt gcagatttct ccgctggcat
     1981 gtcatttgtc tgcctgtctg caatttcaat catcgcctct ttctgcccgt ctgtaccatc
     2041 ttctgcaaat tccacggtta cataattaga ggctttttcg tccaccgaag acataacagt
     2101 ctccgatgga taaaaagcct tcaccatatg atatgcatta tatacaaatg tctcctgatt
     2161 gcatataacc cggatcattc ttagccctcc tgtacatatg ggttgtgaag cttctcatac
     2221 tctatctttg tctcacccat atgtcccgga taaacaatcg tatcatccgg aagtgcgaac
     2281 agtcgttctc ttacagaacg tacgattgca tcctgactgc tgttcggaaa atccgtacgt
     2341 ccgacagaac gctggaataa agtatctcca ctaaatactg catgttctac aggcagataa
     2401 tagcaacagc ctcccatcgt atgtcccggt gtatgaatga cttctatcgt ctcacctgcc
     2461 agttccagtt tttgtccgtc ttttaacggt tttgcaccat caaaggaata accattcgtg
     2521 taagacgaag acagattcag ctctggatcc gtcataatcg gaagatcctc ttcctctaca
     2581 tagaccggaa tattccagtt ttccagaata gaatcaattc ccataatatg atcgaaatgt
     2641 ccatgagtca gaagaattgc cacaaggtta agtttttctt cctcaatgta tgctgtaaac
     2701 ttcttagaat gtccacctgg atccactaca actgtatcct ttgtctcttc atttatcaaa
     2761 aggtaacaat tcgcccccaa aatcccaagg gaaaatttct ctatcttcat tgctttttct
     2821 ttcctcctag cctgttgttc tctcaatatc gatcacgtca tcaatctgac gcagtttacc
     2881 aattactttt gcaagttcct ctcggccatg cacaataaat ccagcctcga tggtcgcagt
     2941 tccctgcttg ctcgtgcgga tatttaagga tttgacatcc atctccatct ccgtaaatac
     3001 tttggaaata ctcatcagaa gtccctgctg atctcttgca tacatcttga tctcagccag
     3061 atactgacct cctgtctctt ctgccacatt tccttcccac tcagccggaa tcagtcttgc
     3121 acgttctgct tctgtcaaat gtatcatatt aacacaatcc gtgcggtgaa tcgaaagtcc
     3181 tcttcctctt gtaacaaatc cgacaatctc atctcctggt accggattac agcatctgga
     3241 aaaccggact gccacatcat caattccttt tacgacaatt ccactcttgg acttggcaat
     3301 atggacttta ttcttagccg cctctgcaac tttttcaagt acaatttcat ctgtcagttc
     3361 ctgcttgtga tccttgccat attcttccgc cagacgattc acgacctgtc cttcttttaa
     3421 gccgccatgt ccgatcgcgg caagcacaga atcccagtcc ttgaatccat attttctctg
     3481 tacgatctct tcatattttg gctggagcag attagaaagg ttgagagatt ttgctttgca
     3541 ataggaggcc accatctctt ttcctttgat aatattgctc tctttaaatt cttttttgaa
     3601 ccactgattg atcttatttt ttgcctgtgt actcttgact acattcagcc agtcacggct
     3661 tggtcctttc gaattctggg aggtcagaat ttctattctg tctccattct ggattctgta
     3721 atcaatcgga acaagctttc cattcactct ggcaccgacc atcttattgc cgactgcact
     3781 gtgtatggaa taagcaaagt cgattggagt ggaccccgtc ggcaatgtct ttacatcccc
     3841 ctgcggtgta aagcagtaca catcatctgc aaacagatcc agatctcctt tgatgaggct
     3901 taagaattcc ttgttgtcag acatatctct ctgccattcc agaatctgtc tgagccagct
     3961 cattttctct tcttcagcca taacaccttt cttgctgccg ccagactctt tatacttcca
     4021 gtgagcagca ataccatatt cggctgtctt atgcatctcc tgtgtacgga tctggatctc
     4081 aaacggctga ccgattgaac tcatcaacgt tgtatgcaga gactgataca tattcggttt
     4141 cggcatggca atataatctt taaatcttcc aggaatcggc gtataaatct catggataat
     4201 tcccaatgcc gcataacagt ctttgacaga atccacaatg atacggactg caaacaggtc
     4261 ataaatctga tctactgtct tatcctgatt gaccatcttc ttataaatac tgaagaaatg
     4321 ctttacacgt ccatttacat ctgctttaat ccccgcattt ttcatatgca tggacacttc
     4381 atccacaatc tgttggacaa attcctcacg ctctgttttt ctggcattga tctgatttac
     4441 aagatcaaaa aatacatctg gtttcagata cttcaatgac aaatcgtcaa gttctgtctt
     4501 aattttagaa ataccaagcc ttcccgcgat cggcgcataa atatccattg tctcacgagc
     4561 cttttcctgc tgtttggccg gagtcatgaa ctgcagtgta cgcatattat gcagacggtc
     4621 cgcaagttta atgataatga cccggatatc ctttgccata gcaaggaaca tctttctcaa
     4681 attctccgcc tgaagttcca gtttgtccgc agaataagct acacggccaa gtttcgtaac
     4741 accgtctacc aaaagagcta cctcttctcc aaactcttct ttgatataat cctctccaat
     4801 ccgagtatct tccactacgt catgaagaag agctgcaata attgtctcct tatccatctc
     4861 aagatccgca agaatgatcg ctacccagag cgggtggata atatacggtt ctcccgactt
     4921 tctcttttgg tctccatgcg ctttttttgc cagattatat gccttctcga tctgagtaac
     4981 atccgcagac ggatgatact tttgaatacg ggcaattaac atgccataaa gcttatccgg
     5041 atcatcataa tctgcctcct gtttgattcc gtgcccatct accatctgaa gtttccctct
     5101 tgtgtctttt agcaatgctt ccggagcaat cttgccgtcc agtgactcat atgttgtttt
     5161 attctctgac atattaacgc ctccttccct ctctagtctc tcaaatgtat atctttttct
     5221 attttccagg atatacaata actgaatcta tatcatatcc ctgtaatctg tcacgtccat
     5281 gaagtcctgc cagttccatt aaaaacacag tctttacaac ctttccgcca agaccttcaa
     5341 tcaaatggat cattgcctca ttcgttccgc ctgtcgcgat cagatcatca atgatcacaa
     5401 ctctctgccc tggcttgatc gcatctttgt gcatctcgat agttgctgtg ccatactcta
     5461 attcatactc tgcagaaacc gtctctcttg gaagctttcc ttttttacga atcggaataa
     5521 atggcttttt cagattatat gcgatcggta ccccgaaaat aaatcctctg gattccggtc
     5581 cgactactac gtcaaagtca agaccttcta atttttcctg catcagatca attgcaagat
     5641 gcagtccttc cgcgtcctgt aatacacttg tcacatcacg aaatatgatc cccggttctg
     5701 gaaaatccgg aatacttact acataatctt ctatcggttt cataattatt ctctccttct
     5761 tctctttcaa ggtaaagtat atcttttagt atagcattat ttgttccatt tttcaaaaaa
     5821 aatctatcga taatgggtaa ttacaatctg aatttgtctt tctccccgga attcattgat
     5881 tccagggtaa aatgtaatgg acattttacc attatttctt tcacactgtt ttgcaaattc
     5941 ctgtgcatca tgaaaacaga tggcttccat ccggtttccc gccgcatcga ttgctgttgc
     6001 ttttgcaaca tttttatttt tcccgatgat cttcacatgc tgcatggcga cgcctcttgc
     6061 cgcaaaaacc ggttttgtat taccttttcc aaacggttcc aggtattcaa gttcttctat
     6121 aaactgttcc gtaatagcag taaatggcag ttccatatcg atcactactt tttctgtcag
     6181 ctcttcttct gaaagcgtac actgatcatt tagtcttctt ttaaatttct caacattttc
     6241 tttatcaagt gaaagtcctg ccgccatcgg atgtccgccg aattttgtca gaagatcccc
     6301 acagcctgtc agttcttcat acatggaata gctttcgatc gatcttcccg atcctttgac
     6361 tccatcttcg gaatccgtca atacaaatac cggacgatag taattttctc tcacacgtcc
     6421 agccacaagg ccggcaaggc tttcatgaca atccggcaga tagataacaa gcaccttatc
     6481 cccccggata tctgtctgtt ccactttcgc cattgcctca tctacaacgc ggtctgtcat
     6541 atctctacgg ctctcattca atgctttcag atcacctgcc agcatatctg cctcccgctc
     6601 tgtctttgcc cgaagcagtg ccagtgctct ttttgccgta tccagcttac cactggcatt
     6661 cagacacgga gcaagaataa atccgatgtg atatgcctga atcttttttc cctccagccc
     6721 gatacactgg atcagggcac gtagtcccag attagatgtc ctctttagca tctcaagacc
     6781 ctgcttcacc agaattcgat tttcctctgt cagatccatc acatctgcca ctgttgcaat
     6841 tgcaacattt tccaaaagat aatccagatc cgccacatcc tgaccatttg cctcacagat
     6901 tgcctctaca agcttgtatg caaccgctgc accacataat cctttaaatg gatattcaca
     6961 tccttcctgc cttgggtcaa caactgcatc tgccggcggt aaaatgtatc ttcttcccgc
     7021 ttcattttcc ttgtacggca cttcatgatg gtctgttacg atgatcgaca taccaagcgc
     7081 ttttccatac tcaatttctt tcgctgccgc aattccgtta tcgcaggtga tgatcgtatc
     7141 aattccatct gcatgcgccc ggtcaatcag atgctgattt aatccatatc cgtctttgat
     7201 acgatccggg atgtcgctgt ccacctttgc gccaagcttt tccagacctt ctaaaagaat
     7261 atatgtcgca ttgattccat cacagtcata gtctccaatg acacggattt tttcccggtc
     7321 cctgattttt tcagtcagaa tttccaccgc ctgtggcata cccttcatct gcattccatc
     7381 gtagagttcc gcaattgtac cgttcagata ttggttgatt gcttcatctc caataacatc
     7441 ccggttacgg atcagactgg ccagtctcgg actaatatga aatttcttac tgatagcctc
     7501 aaaatcagca ccttttctta aaagtaccca gcgttccata attttcgtct ctcctgtttt
     7561 atccaagtaa atatttgcaa agtaaatact acactttcaa cgggaatctc caacatcatt
     7621 ttatttactt tgcaaatatt tactttaaga aaagaacagc ctcgccataa aatatgactt
     7681 tggctgttct atagtattta aaattacttc ttgaagcgtt tcattacata ccacagcgct
     7741 cctgtgatac atacagatga gtaagctccg catacaactc cgaccatcaa tggaagtgca
     7801 aactccttaa tagaacttac acccatgacg taaagtacag ctaccatgat aaatgttgta
     7861 agagatgtat agatacttct tgtcagcgtc tgtgtgatac tcttgtttac aactgctgca
     7921 acatcactgc tctttgtctt accacgcatt tcctctcgga tacggtcaaa gataacaatg
     7981 gtcgcgttga tggaatatcc gacgattgtc agcatacacg cgataaatgt attaccaaca
     8041 gagattcttg caattgcata gaatcctact acaacaagga cgtcatgtaa aagagcaagt
     8101 accgcactgg tagcgaaacg gatatctttg aatcggaacc agatatacag aagcatacag
     8161 attgtcgcaa taacaaccgc gataactgca tctcttcgca tctcattact tactgtagaa
     8221 ctgatatttt ctgccgtgat ctttgattcg tccacaccga agttatcaac catagcctta
     8281 ttcagtgctt cacgcttgtc aagatccagt gtaactgtct tgataataac ctgattggtt
     8341 ccggctactt tctgagtctg aacattgtta tctccagtta ccttttctac aaccggaaca
     8401 atttccttat caatctcatc aatagagtaa tctttatcaa atgttacatt tgtagatgta
     8461 ccgccttgga attcaaggct gtatgcaaat gctccttttc ctcttcctgc attgacaccg
     8521 attgtgatca ctcctgctgc aattaataca agagaaattg taaagaacac ttttttcttt
     8581 gaaaggaaat cgattggctc acgctctttc tttggacgat aatataattt ttcacttcta
     8641 agtccaactg cataaaatgc atttacgatc aatcttgtaa taacaagtgc tgtaaacata
     8701 gatgcgatga taccaattgc aagtgtctgc gcgaatcctt ttactgtacc ggaacctttg
     8761 aaccacaata cagctgctgc aatcagagtc gtaatattac catctaaaat tgctgataaa
     8821 gctttctgga aaccaatctt cagagaattc tttacacttc ttccgcgtac catctcttca
     8881 cgtacacgag cgaagatgat aacgttggca tctactgcca taccaatgcc aagaatgata
     8941 ccggcaatac ccggaagtgt caatgttact tcaaatgcat tcaggattac aagtacaagt
     9001 cctgtataga ttaaaagtgc aagtccggat gcaagtcccg gaagcaagta tacacaacac
     9061 atgaatacaa atacaattgc aagtccgatt gctccggctt ttaagctggt cgcaactgcc
     9121 tgctcaccaa gctgggctcc tacaacatta gaacgcaact cttccagttc cagtttcaga
     9181 ccaccgatac ggattgtaga agcaagcgca tctgcttctt cataggtcat gttaccactg
     9241 atctgagcct gtccatttgt aatggctgcc tgtacattcg gaacacttac aaatgctccg
     9301 tcataataga taccaatgct ctggcttgct gccagtgctt ttgttgttgc atctgcgaac
     9361 tttgttgttc catcttttgt aaatgtaaga gatacaacat tctgtttatt ctttgtcagc
     9421 tggtcttctg ttgtctgagc ctgggcactt tttacatcat tgccactcag tacaatagaa
     9481 ccgtctgcct gcaattcttc aattgtcttg ttaagctgat aatctttgga cgcatctccc
     9541 gtactgttca cctgactgta gtttgctgag ccgtcactgc ctgtctgcgc aataaaatac
     9601 agggaacccg gctgtcccag ttcgtctaaa atctcattgg catctgtaac accaggaatc
     9661 tcgatattaa tacggtcgct tccctcctga tatacacttg cctctgtact atactgttct
     9721 acacgctttt gcagcttata gattgtatca ctcatctctt catccgacgg attgtcatct
     9781 ttgacctgat atgtgatact tacaccaccg gcaaggtcca gacccagttt gatattcttc
     9841 atagaacctg tatggccttt tccgaatcca acaattgtcg taaaaccaag cagtacgatc
     9901 aaggctgctg ccacaataag actaagtatg cctctgcttt ttttcatgat ttacttcctt
     9961 tctctttctt ccattccttc gaaggattct atgttacaca ttatgcatct gccagtgctg
    10021 ctttgatcat aatggcacat tccacacgtt tacgctgcat ctcacagcca acatcataac
    10081 aatcatggat cgttccatgg aaattataag agtttgccat acatccaccg ctacagtaga
    10141 atttagcgaa acaattttta catttttctt ttgaatatac actgcagctt ctgaaatcat
    10201 ctgcaatctc cggctttaca attccatcgt ctacatttcc catcaggaat tcttcctgcc
    10261 cgacaaactg atgacatgga tacagatctc cccatggtgt gacagacaga tattctgttc
    10321 cggaaccaca gccggacata cgtttcatca cacatgggcc gccttccaga tcgatcataa
    10381 agtggaagaa attaaatcct ttgccttctt tctctcgttc gatcataatc ttggcaagtt
    10441 tatcatactc ttctttgatc tgtggaatat cctcttcgcg gatcgcatat ggatcggatt
    10501 cgtcacctac gaccggctca atggacatct gcttgaatcc aagatctgca aaatgcagga
    10561 tatcattgga gaaatccaga ttatttcttg taaatgtccc acggatataa tacttctcct
    10621 gattacggct ttcagccagc ttctggaatt tcggcacgat cagatcgtag cttccttttc
    10681 cgttgcggaa cggacgcatc ttatcattga tttcttttcg tccatccagg cttagcacaa
    10741 cattgtccat ctctttattg acaaactcct gaatctcatc attcagaaga acgccgttcg
    10801 tcgtaactgt aaatcggaaa ttcttgtcat gaagcttttc ctgttctctt ccgtatgcta
    10861 ccagatcttt gacaacctgc cagttcataa gtggctctcc tccaaagaaa tctacttcca
    10921 gatttcttct gcttccggaa tttgcgatca ggaaatctaa tgccttcttt ccgacttcat
    10981 aactcataag agcacgtctt ccatgatact cgccttcttc tgcaaagcag tacctgcagg
    11041 ccagattaca gtcatgtgca atgtgaaggc aaagagcctt tacaactgtc tttctcttct
    11101 tcacgattgg aacaagatat tcaaactcat cctttgtaaa taatttcccg tcctctgtca
    11161 gttcaatgac atcatcaaga gcatctctta aatcttcctc gctatatgta tctccaagcc
    11221 gctttttcag attctcccat gtaagatcac tctttaaaat ctcagctgtt ggttcttcgt
    11281 ccggttcatt cagtacagcg atcacatcat agcacaggtc atcaaccaca tgtacggctc
    11341 cactgtatac atccagaaca atgttatatc cgttattctt atactgatga atcacagtaa
    11401 taatctcctt ttctattttt tctatctctt taaaatttta atggttattt ggcaacagaa
    11461 cagagacagc gaccctttta agaccgctgt ctcctggttt tttacctatg ttcttttact
    11521 tatttgctct gctcacaggt ctgatttcct actgtacagg aagtcttgca tgctgactgg
    11581 caagatgtct gacattcgcc gcaaccgcct tttttcactg tcttgttcag agtctgtgta
    11641 ttcaatgttt tcacatgttt catcactaca ttcctccttg tctttcttga cttttataag
    11701 tatagcatct tcctttcttt ttcgcaatat ttttatctga atcgttaatt tttaattatt
    11761 cccgttaata ttttaattac ctgcaaaaag gtggtttttt caattttact atgttacact
    11821 tgcgttagat tacaaatgaa tcagaaattg ccacttcatt aatatgtctt ataggaggta
    11881 attgtaacat ggcaatttca attggcatta acggattcgg acgtattgga cgcgttgcac
    11941 tccgtatcgc catcagtcga ccggaaactt ttaaattatg tggaattaac gcaagaaatg
    12001 cggatcttga ttatatggtc tatatgatcc gctacgactc tacatttgga cgtttccagg
    12061 gagaacttgg aacttatgaa cacggactta tcattaacgg gcagaagatt cctgtcttca
    12121 cagaaggtga tgctgcttcc atcccttggg gttcctgcgg tgccgaatac atcatcgatg
    12181 caaccggagc attttgcacg gcaaaaaagg caagtgctca cctgcaaggt ggtgcaaaaa
    12241 aagtcattat ttctgcacct gcaaaagatg aagaaacacc tacattcatc atgggaatca
    12301 accataccgg ttattcgaaa gatatgtccg ttgtgtccaa tgcatcctgc acgaccaact
    12361 gtcttgcacc tatctgtaaa gtactggaag acaattatgg aattgaatat gggctgatgt
    12421 ctacgatcca cgccgcaact gccaagcaga aagttgtgga cagccgttct ctcaaggact
    12481 ggcgtaccgg acgttctgca ttcggcaatc tgattccatc cacaaccgga gccgctaagg
    12541 ccatctctct cgtcattcct tctctgaaag acaagatgag tggtatttct tatcgtgttc
    12601 caactacaga cgtctcaatc gttgatttga acgtcgcgct aaaagagtct gcatcttatg
    12661 aggatatctg caaaaaagta aaggaagcct ccatgacata tttgtccggc attcttgatt
    12721 atgtagatga tgaagttgta tcttctgatt tcatcggaga tccacacgct tctatctttg
    12781 atgcaagaca gggaattcaa gtaaattctc atttctttaa ggtcatctgt ttctatgata
    12841 atgaatgggg ctatacaagc cagatcttcc gcctcatcaa gtacatggat caggttgacc
    12901 ataattcata agatgccggt ggaaacactt tccattctgg tatctttaca tttttacatg
    12961 tggcaaaaac tttctgattc gagctgtaac tattctactt tctgtaaggg acatatacat
    13021 tcgtcattac gattatgaac cgtacgtaaa ataaaagctg cctatatctg tttccttttt
    13081 acaatagata tacgcagctc ttatttttta gcctttcatg atatcatacc accggtcata
    13141 ccgccgcctg cacatagtat cagtgatgtg acaatactta cactgtctcc attcagagtt
    13201 ctgtaaactc caagtgtaat gagcaaaagc aatacaaaat ataggattcc aagaaccatc
    13261 ccccacaagt accgttttga ttttgtcagt ttccctatga tcactcctcc gatcaatgtt
    13321 gacactacat agattccaac aattgccgcc gatacaattt tttcatttaa ttcaaattta
    13381 tacataaaaa atgtcaaaac caaaagtaat ataccggtga caatataaga agccagaagt
    13441 gacttgatcc accatatgac ctttatattt ttttgcatat tctccatctc tttcctcctt
    13501 gtctaccaca aggtatgagc cagatccggc gaatatgact gcttctgcaa attttatcac
    13561 tccatttgct ttccaagaaa tcctgctgca catgctccca gcttttgttc cagttttgta
    13621 aacttctctt tttcatctga tgacagtaaa ataactgccc ccacaacatc tccttcgcaa
    13681 atgatcggtg taatagattc ccatacataa tccttttcct gttcccggaa cacccggata
    13741 tatttcttct catcaacctt tgccagaata ctgtttcttt cttccagttc cccttgaaga
    13801 actttgctga tatacttttc ctgcacctct tttctcccgt ttccggaagc tgccacgacc
    13861 tgatccatat cacagataca cacaaggcac cctgcctctt ttgccaggct gtctgcatac
    13921 atacctgcaa atgcagcaag ctctccgatc ggtgaatatt ttttcaatat aatctcgcct
    13981 tcccggtcgg taaatatctc cagtggatca ccttctctga ttctaagtgt tcttcgtatt
    14041 tctttcggaa tgaccacacg tcccaggtca tcaatccgac gtacaattcc tgttgccttc
    14101 atatgattcc tccatgattg attccgcatg gctgttcttt cttctcatgc taaattttac
    14161 ttttaatgct attatgtgaa aatgcatgaa aattattcta ataaaggaag cagaattcaa
    14221 gcattgcata acagaacctt tcaagctcca aacttctgtt tattaattgc aaaattttct
    14281 atttttctac tttttttgca attaattgca cgaacttgat ttttttttta atttatgcta
    14341 tattcataca caagatagga ggaatggtaa atgattgata cacataaact caaaaaaaga
    14401 gatttatatc taaataaaat catcgcattt caagataccg aacctgtaaa agttgttact
    14461 ggaatccgca gatgtggaaa atcgagcctg ctcaaattaa tggttttaca tctgaaggaa
    14521 agtggcatta ctgatgagca gattcttgaa atgaattttg aatcccatgc ctttaaaaat
    14581 atgaacagtg actcttttta cgaatatgta aaacaacata tcgtccctaa taagagaatg
    14641 taccttttct tcgacgaagt tcagcgtgtt cctaactggg aagatgctgt caattccttc
    14701 cgtgttgatt ttaactgtga catttatgtc actggttcaa atgcctatat gctctcctct
    14761 gaatatgcca cttacttatc cggcagatgt gtagagatta aaatgttacc gctttctttt
    14821 tctgaatttc ttacttttca tggctttgaa gtcagagaaa taaaaagttc attgggaggt
    14881 attcgcaaac aagccttcga taaaaatgat gaacgttatg aacttcgaga cgtttttgat
    14941 gcttacatgc gatttggcgg aatgccaggc attgccgata taggattaga ccaggaaaaa
    15001 gcattgatgt tactcgaggg catctactca accgtaatta tgagagatat tcttgaacgc
    15061 gaaaaccgca aaggacaaag tagaatcact gatcctgttc tcttaaaaaa aattattatg
    15121 tttcttgctg ataatatagg aagcaatata tctgtctcat ctatcggaaa tactttgatg
    15181 aatgaaggat tgcttgacaa cggaaagcga aaagggacac ctagtgttca taccgtccaa
    15241 tcctatataa atgcattgct ggaatcatat ttcttctatg aaatcaaacg atttgatatc
    15301 aagggaaaag aatttttaag aactttgggg aaatattata ttgtggatat aggacttcgc
    15361 aactatctac ttggttttcg aaatcgcgac agtggacatg cattagaaaa tattgtttac
    15421 ttcgaattac ttcgccgggg ttatgatgtc tcaattggaa aaatagacaa ttctgaagtg
    15481 gattttatcg caacaaaagc ggataataaa atttatgttc aagtcactga atctatgaca
    15541 agcgaagatg ttcgcaaacg tgaactgtct cctcttcaaa aaatcagtga taattacgaa
    15601 aaaattattc tttctttaaa tcccggaatg gactcttcat ataatggcat aaaatccatc
    15661 aatttgattg attggttaat ttcagaataa tatcacaaag cgttctctga aaaagaaaag
    15721 gttgcctttc ctggcagcct ctcttttcaa aaaaatacct ctaaatctct gaaaatactt
    15781 ccaaatgttt ccgttttaca tatcatctgg ttcaaactga ttcggataga agtcgctccc
    15841 ctcataaccg caaactccca ttctaggaga attcgtaact ggaagcagat atccgctctc
    15901 ttcaacttct atttcttcat ccagttcccc attttcatat ttttccagac actcctcgca
    15961 ccagaacgga tcttcattat acatttttat aggatcaatc cacacagcgg gattttttcc
    16021 acaaactgag catgtaaact gtatcggatt atttctggat aaaatcgtca cattttcttt
    16081 ctgttctgga gctttataaa aatctaccac ctttattgta agctcggttg tggaaccaaa
    16141 atcatattca tatccaattt ccattcccac ctcaagcact tctttgagtt tatggctcat
    16201 atcttctgca ggttttcccc acaggaaatc attatctgga atgtgttcat atctcacacc
    16261 ttcaatatca aatgcgctca aatgtccaca acattccacc cagatatcgc gtataaattg
    16321 atccagacac tccaaagttg cattttcttt tatctgtata ataagccaat aatctttgtt
    16381 atatgtacca tataacatta attcataata agctgacatc ttcttggaat tttcacacac
    16441 ttccatccgc ttcttacaac tctgcaaatg ttttagcata cctgttcttg tatattcttt
    16501 tccacaatac ttacaatatc ctcttgtact ctttgccatt gtccgatttc ctccttaata
    16561 tcaataatgg atatgttcat tggcatagcc actatgaata ctcaccaaag gcgattcttt
    16621 cgctttttta caacctccac ttacagacag aactcacctt tactcatcct tcacttcttc
    16681 gcctgcaagc ttcaggatat cttctacggt gtcttccgta atacccatac gctctgcgac
    16741 ttcatcgacg gatacttttc ttccgtattc ttccttcatg cttttgatgg tctcgtccag
    16801 atcattcacc cgctcgacca tcttcttatc gcggcgtttt tcttcggtgt gggattccag
    16861 catcacccgg attccagcgc ggacctgctc cagcacttct gcttctgttg ctttcttatt
    16921 ctcacctaag tacagcatca agctaacatt gccttcctgg atcacatcac cgatgaatat
    16981 tcccggcata tgcagcttta ctgcttcttc tacaactttc ggaagataat atgcaagctt
    17041 cacctcttcc tctgtctgtt ttgccatttt ttcaatatcg atcagatatt ctgccacata
    17101 gtctttttcc tgctggctta gtgtatcttt ttcttcttgt tctgcttgtt ctgtattttc
    17161 tatagttcct gtatatccga tcacttccac tttctgtgac atcaggaatt catggacaag
    17221 attcatctgc tcatctgtaa gattgtcgtc ctgaaagaaa gcttgcactt cctgactagt
    17281 cattttatta ttctggcttg ctgcaactgc aagaagctct cctaattttt tctgaaactg
    17341 ggctctgtct gccatatctt tactccttcg ttaaattttc tttacctttt tatcattcac
    17401 gttcctgtta ttcaagaact ctcttcaaat gtcaataatg aaatgccgat agctcttcat
    17461 atcttctggc atctgttctt cattacactc cttcgtagga aaaatcagga ataaagcttt
    17521 cttttgccgt ttcgccttcc tgaataaatg cctgctccac gccaagatct atggcataat
    17581 ccaccagaac atcatatgct tttttcgtca ctttcttggc aagctccgga tatttttccc
    17641 gattcaacgt atcgagtgga gtgtactggt tcatgagact catataaatc tggtcaccat
    17701 atgtttcata gaggtatttc acaattcttc tcgcatctct cagacaccca ggcaataaca
    17761 aatgtctcac aattacacct tttgtcataa tccccgcatc attaaataca ggattcccag
    17821 tctgccggac catttcttcc agagcagcct ttgccacctc aggataatct tctgccccgg
    17881 aatatttctt tgcatgctcc ggatccagat atttaaaatc cggaagatat acatcaacat
    17941 atccatttag cccgcgtaaa gtctccacct tttcatagcc gcttgtatta taaacaattg
    18001 gaagattaaa cccttttttc cttgcctgat ccagtgccgc gataatctgt ggtacaaagt
    18061 gcgttggtgt cacaaggtta atattgttcg ccccctgttc ctgaagctcc agaaatatct
    18121 ccgataaccg ttcaacactt actgtttttc caacctcact gttggcaatg tgataattct
    18181 ggcaatatac acatcgaagc gtacagccag agaaaaaaac agctccggat ccatttgtcc
    18241 cggagataca cggttcttcc cacatatgaa gcgcggctct ggaaagccgg accaaatccg
    18301 actccccaca aaagccacgc tttccttctt ctcgcttaat ctggcactgt ctcgggcata
    18361 acatgcaccc gttcactaga caacctgtcc tttcgcaaca aatacaggaa acgcttcatc
    18421 accctttaat tcttttccat cggtgatttt tacattctta tctgaaatga tatattccag
    18481 ctttgtacct tctccaacga tcgtatcctg cattaaaaca caattcttca ctttcgcacc
    18541 ttttgcgatc ttcacaccac ggaataaaat actgttctcc acttcacctt cgatcacaca
    18601 accgtctgct accataacat tacttgcttt tgcattgccg atatatctgg tcggattatc
    18661 gtcacgaatc tttgtataga tgggattacc tgtgaaaagc tcctcaagat tcttatcatc
    18721 cagaagtttc atgttctcat caaaatagct cttaagtccg gtgattctcg ccacatatcc
    18781 tttatgctca taagccatga ctttatatgt atccagatgc gggatcagga tatccctctc
    18841 cagtgaaata gctccacgca taaacgctgc attaatggta tcgatcagcc actctctgtt
    18901 cgcaatgtat atattcatag agaaattctg cacaccctgc tcctgcttat tgatgtagat
    18961 gtcttctact ttatctccat ccagcttcaa cgtataataa agccctttac ttgcatcttt
    19021 tgcaccagtc agttcctgtg gcagttcctc ttttgtataa gcgaacgtaa tatctgcatc
    19081 cgtttttaca tgctgtgcga tcagcgcatt gaaatcaaaa tttgcagcaa tattcgtatc
    19141 tgccataatc acatattttt ctttttgctt tttgagtacc ggaagaatat tggcgagcgc
    19201 ttccactctt cctcctccca tactgccgat agacttctgg gcaaatggag gaaagatact
    19261 aagtcctccg ttcttacggc tgagatccca ctctcggcca ccacctagat ggtctacaag
    19321 cgaatgataa ttctcccgaa caagcacttc tattttatca attccgcagc caaccatact
    19381 ggataacaaa aaatcgatca ttcgataacg gcttgcaaat ggaatggaag ccattagtct
    19441 ttcgctgacc agttccggaa caaacttatc ataattattc gggaaaataa ttcccattgc
    19501 gtccgcattt gcatttatca tttttcttca ccgtccttta catcttcact gatcatggca
    19561 ttcggtccaa tcttggcacc tgttccgacg cagacatccg gtccgatggt tgcaactcct
    19621 tgctcatcct ctgtcggcat agctcctacc acagcatttt caccgatcac tacattctcc
    19681 gcaacaatac aatgctttac actggctccg gctttgatcg ttgttctgcc cataacgact
    19741 gcatcttcta caactgctcc ggcttctact ttcactccgg caaataggat ggaatgtttc
    19801 acactgcccg caatcttaca accatctgtg atcatagaat tctccacact ggctccggcg
    19861 cagatcttat ggcccggcat accactgttc cggctataga tcttccagtc ttcatcaaac
    19921 aggttaattc cactgtgttc cggatccagt acttccatat tcgcttccca gagagatgga
    19981 atcgttccca catctttcca gtatccgtta aagtgatacg cgtacatttt tctgtcatca
    20041 cgcagaagat tcggaatgat attatttcca aaatcatttt cagactccgg atccgcttcg
    20101 tcttcaatca gatactgctt cagaatatcc cagttaaata tgtaaattcc catagatgcc
    20161 agattagact tcggattctt cggtttttcc tggaattccg taatacggtc atcatcgtcc
    20221 gtgaccataa gtccgaatct tggtgcctcc tcccacggga cttccataac cgccacactg
    20281 aattctgcgt tcttttcttt gtggaatcta agaaaatcac tataatcctg cttgcagatc
    20341 tgatctcccg ataaaataat gacatattcc ggatcataac gctcgataaa tgaaatattc
    20401 tggtaaattg catttgctgt acctttatac caatctgagc cagatgcctt ctgatatggt
    20461 ggtaatacat gaactcctcc atagattcgg tccagattcc acggctgccc atttccgata
    20521 tactcattca gctccagagg ctgatactga gtcagaatac ctactgtatc aatacctgaa
    20581 tttacgcagt ttgaaagtgg aaagtctatg attcggtact ttccgccaaa tggaactgcc
    20641 ggttttgcaa gcttctgggt cagcgcatac agtctggagc cctgccctcc ggcaagtaac
    20701 attgctatca tttctttgcc cattatagtt cccctttcta attctatcat ctacccgtaa
    20761 aatgacagat tatttattct tgatataaaa atattatact atatttcagt tattttttct
    20821 acaaactcac ttgttgtttt cccaaaattt ttgttagttt tctgttaatt ctaatatccg
    20881 aatgaagcat tatttctgta cgaatctttc tttcaaaatc caggactgga tattttcaat
    20941 ctagtcttgt ataataaaag tagtaatttc gaggaggata tgtatcatga gtaaaattga
    21001 tgaaattaga agtgctatgg tcgcagctat gaaagccggc gaaaaagaga aaaaggaaac
    21061 tttatccatg cttctggcag ctcttaagaa taaacagatc gacaaacgtg cagatctgac
    21121 agaagaagaa gagattcagg ttatcatgaa agaaatcaag cagacaaaag agactttgga
    21181 aatgacacct gctgaccgta ccgatattat tgaagaatgt aaccgccgcc tgactgttct
    21241 ggaagcctac gctccaaaaa tgatgggcga agacgagata aaggcaatca tcgaaggtgt
    21301 gttatctgaa cttggtatcg agaacccaac cggaaaagac aaaggaaata ttatgaaaca
    21361 cctgatgcca aaggtaaaag gtaaagctga tggtaagctt gtcaatgatc ttgtatccac
    21421 atatttcaaa taattttacc atataggaaa ttccatcttc tatatgatag aaaagacctg
    21481 ccaaccgaca ggtcttttct tctctatgga aattttttca tgtctttcag acttactgca
    21541 ttttaattat ctgtctgagc ctgatcgtct gtctgcacct gatctgcata cggtgtctga
    21601 gtctcagtct tcatcttcac agacactttc tggaaactta cttttttcca tacactctta
    21661 tgc
//
