LOCUS       NZ_CP030865            21068 bp    DNA     circular CON 14-AUG-2024
DEFINITION  Micromonospora sp. B006 chromosome, complete genome.
ACCESSION   NZ_CP030865
VERSION     NZ_CP030865.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sp. B006
  ORGANISM  Micromonospora sp. B006
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Complete Genome of Micromonospora sp. Strain B006 Reveals
            Biosynthetic Potential of a Lake Michigan Actinomycete
  JOURNAL   J Nat Prod 81 (9), 2057-2068 (2018)
   PUBMED   30110167
REFERENCE   2  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2018) Medicinal Chemistry and Pharmacognosy,
            University of Illinois at Chicago, 900 S Ashland Ave, Chicago, IL
            60607, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 77.6x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003408515.1-RS_2024_08_14
            Annotation Date                   :: 08/14/2024 03:31:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,342
            CDSs (total)                      :: 6,278
            Genes (coding)                    :: 6,199
            CDSs (with protein)               :: 6,199
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 20 of 79
            Pseudo Genes (incomplete)         :: 62 of 79
            Pseudo Genes (internal stop)      :: 6 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:07:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4216763
            Orig. end                         :: 4237831
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="18"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11068)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(871..886)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.19"
                     /tool="antismash"
     tRNA            complement(1467..1539)
                     /anticodon=(pos:complement(4218267..4218269),aa:Asn,
                     seq:gtt)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MicB006_RS18830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MicB006_3791"
                     /product="tRNA-Asn"
     gene            complement(1467..1539)
                     /locus_tag="MicB006_RS18830"
                     /old_locus_tag="MicB006_3791"
     misc_feature    complement(1476..1489)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.79"
                     /tool="antismash"
     misc_feature    complement(1656..1670)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.59"
                     /tool="antismash"
     gene            1807..2199
                     /locus_tag="MicB006_RS18835"
                     /old_locus_tag="MicB006_3792"
     CDS             1807..2199
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475576.1"
                     /locus_tag="MicB006_RS18835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3792"
                     /product="hypothetical protein"
                     /protein_id="WP_116507857.1"
                     /transl_table=11
                     /translation="MRGKIMFLGGLAAGFVLGARAGREKYEELVVRGRKVLDHPTVQEA
                     AGVAQAQATRLYSEGKDKLGQTKLGEKLATGNGGKPGMTEADKPFAGTPAAVGSRANGT
                     GSTSSTSTSGSTTTGTSTKPSTGNTL"
     gene            2296..3480
                     /locus_tag="MicB006_RS18840"
                     /old_locus_tag="MicB006_3793"
     CDS             2296..3480
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287897.1"
                     /locus_tag="MicB006_RS18840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3793"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_116507859.1"
                     /transl_table=11
                     /translation="MPMVGPETADQARLLRLLRDDGPRSRVELTDLLGLPRARFAAEAD
                     RLTALGLVESAGPAASRGGRRSSLLRIGAQVRFGAVLVGGGTLRVALTDGELNPLARHD
                     EPVDVRLGPDVVVGRMVELLGKLRVEAGLTSLTGVGVALPAPVEVRDGTPVSPPALPGW
                     HRFPVRDTLAAELGCPVQVDNDANAMALGERHAGTGRPFDDFLAVKLGDAVGCGLVLAG
                     SLYRGAASGAGDIGHLQLSEDGPLCGCGHNGCVEAYCGDAALVREAVTAARAGRSTVLA
                     DRLAEAGTLSVADVAAAATEGDPAAQVIVRDAARRLGQVLVGLVSFVNPAIVIIGGAPA
                     GIGPVLLAEIRGVVYRRSTPLATGSLPIVLSDLGDTAALIGAAHLVSDQAYAAR"
     gene            complement(3632..4639)
                     /locus_tag="MicB006_RS18845"
                     /old_locus_tag="MicB006_3794"
     CDS             complement(3632..4639)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007463784.1"
                     /locus_tag="MicB006_RS18845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3794"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_116507860.1"
                     /transl_table=11
                     /translation="MARPITLFTGQWADLPFDEVCRLAAEWGYDGLEIACWGDHFEVDK
                     ALADDSYVERKRATLAKHNLQVFAISNHLVGQAVCDHPIDERHQDILPARIWGDGEPEG
                     VRRRASEEIKDTARAAAKLGVRTVVGFTGSSIWHTVAMFPPVPPAMIERGYQDFADRWN
                     PILDVFDEVGVRFAHEVHPSEIAYDYWTTKRTLEAIGHRPAFGLNWDPSHFVWQELDPV
                     NFIFDFADRIYHVDCKDAKVRTGDGRRGRLSSHLPWADLRRGWDFVSTGHGDVPWEDCF
                     RALNAIGYDGPISIEWEDAGMDRLVGAPEALQFVRRLAFDAPSAAFDAAFSSRD"
     gene            complement(4814..6922)
                     /locus_tag="MicB006_RS18850"
                     /old_locus_tag="MicB006_3795"
     CDS             complement(4814..6922)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475573.1"
                     /locus_tag="MicB006_RS18850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3795"
                     /product="ThuA domain-containing protein"
                     /protein_id="WP_116511603.1"
                     /transl_table=11
                     /translation="MKLLRTALGAVTAVLTAIACTVPAGPAAAADAPYDVLVFSKTAGF
                     RHDSIAAGTQAVRELGTANNFTVTATEDAAQFTTANLARFEAVIFLNTTGDVLNATQQS
                     AFEAYIGAGGGYVGVHSAADTEYDWPFYGNLVGAWFASHPAIQPATVKVEDRAHAATAH
                     LPQQWNRTDEWYDYRSNARSTAHVLASLDESSYSGGSMGGDHPHAWCKTYSGGRSFYTG
                     GGHTQASYADAAFRNHLLGGIRYAAGRTKADCRPETGYTALYNGGTTGWSQAGPGSFTN
                     ADATLTSVGGMGLYWYSAKQFTNYSLKLDWRLAGDDNSGVFVGFPPSSDPNSAVDNGYE
                     VQIDPTDAADRTTGAIYGFKSADLAARDAALNPAGEWNTYEILVESERLQVFLNGVRIN
                     DFTNTDPVRSLAGHVGIQNHGTGDDVSFRNIRIKELGGTPPPTGNTTVQAESFGSASGV
                     SAYPKAGANGGQTLGYVDPGDWAAYPGLDLTGVTSLRARVVSGGPGGTLQVRTGSPTGP
                     VLGQVAVPNTGSWTTFADVSTALTGVPSGTQTVHLTFTGSGSGLFDVDDFTLVRSTGSG
                     GTGPIKGLAGKCLDVRNASSADGTQIQLYTCNGSSAQTWTVTSNGPVKALGKCLDVSGG
                     GNANGTKIQLWSCNGTGAQNWSAQADGTLRNPSSGKCLDVSGNNSADGTAVHLWTCTGA
                     ANQRWTLP"
     gene            complement(6940..9774)
                     /locus_tag="MicB006_RS18855"
                     /old_locus_tag="MicB006_3796"
     CDS             complement(6940..9774)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475572.1"
                     /locus_tag="MicB006_RS18855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3796"
                     /product="RICIN domain-containing protein"
                     /protein_id="WP_116507862.1"
                     /transl_table=11
                     /translation="MSSHHHPRARRPLAAAAALLLAATAGTVTAAAAPVPASAHPITAS
                     DFQQVELARGVAETGEPMSLAVLPDRSVLHTARNGTLRRTDAAGATTVIGTLPVYTHDE
                     EGLQGVGVDPGFASNRHIYLYYAPPLSTPAGDAPATGTDFSAWQGVNRLSRFTLNADFT
                     LNQASKVDVLDVPADRGLCCHVGGDIDFDAAGNLYLSTGDDTNPFDSAGYAPIDERTNR
                     NPGYDAQRSAGNTNDLRGKILRIKVNANGTYSIPAGNLFAPGTARTRPEIYAMGFRNPF
                     RISVDKATGVVYVGDYGPDAGTTTARGPSGQVEFNRVTGPGNYGWPYCTGTNTAAETYA
                     EWDFATGTAGPKYNCTGGPTNNSFRNTGLATLPAAKPSWIRYAGDAGSPPEFGGGSESP
                     MGGPVYRYDAANPSTTKFPQSFDGQFFATEFGRGWIKPIHVNADGSPGTIDTFPWAGKQ
                     VMDSAFGPDGAYYVLDYGTGYFNGDANSALYRFDYLGGANRAPVARAAADRTSGAAPLA
                     VAFSSAGSSDPEGGALTYAWTFGDGGTSTAANPSHTYTANGRYTATLTVRDPQGATGTA
                     SVTVTVGNTAPTVVIETPGNGKLFSFGDTVPFRITVTDPEDATIDCTKVKMTYVLGHDQ
                     HGHQITSATGCTGSIAVPVDGEHDDAANIFAVFDAEYTDSGGLTTHTQHTLQPRHRQAE
                     HFATSAGVNTFDKGTAEGGRTVGDIHNGDWIAFRPYLLADATGFTARVSSAGAGGTLQV
                     RAGSATGAVLGSATVPVTGAWDTFTTVTGTITSPPAGTTTLYLTFAGGSGALYDLDAFT
                     LTTPAVRTGPVKGLAGKCLDVRNAATADGTQIQLYTCNGTTAQSWTVTPNATVKALGKC
                     LDVSGGASADGTKIQLYTCNGTGAQNWSAQADGTLRNPSSAKCLDVSGNNSADGTAVHL
                     WTCTGAANQRWTLP"
     gene            complement(10001..11068)
                     /locus_tag="MicB006_RS18860"
                     /old_locus_tag="MicB006_3797"
     CDS             complement(10001..11068)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287901.1"
                     /locus_tag="MicB006_RS18860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3797"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_116507864.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.9e-44, bitscore:
                     148.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTVAPTDPALLRGRFDAELAAFLDARRPGRPDDGTGAVHTALR
                     RFVLAGGKRMRPLFCYWGWRGFGGPDERPIVVAAASLELFHAFALIHDDIVDRSDRRRG
                     APTLHRFFAGLHERSGWRGDPAAYGRQAAVLCGDLCATWSAQMFHGCGLPPERLRRGHV
                     LLARMRSEVIAGEYLDVVAAAGDGSVASALAVVRLKTARYTVTRPVQIGAALAGATPEE
                     VAALAGFGDPLGDAFQLRDDVLGVFGDPAVTGKSNLDDLREGKPTVLLALARASASPAG
                     VARLRELVGDPALDQAGAAEVRGIVEESGAREAVERMIRTRAEAAVVALDAAGLAEPAR
                     RVLAALVERAVDRRE"
     gene            complement(11065..12459)
                     /locus_tag="MicB006_RS18865"
                     /old_locus_tag="MicB006_3798"
     CDS             complement(11065..12459)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475570.1"
                     /locus_tag="MicB006_RS18865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3798"
                     /product="alkaline phosphatase family protein"
                     /protein_id="WP_116507866.1"
                     /transl_table=11
                     /translation="MSRRLVVLDVVGLTPRLLAHMPRLRAVAEAGFAAELGTVLPAVTC
                     SAQSTFLTGELPAGHGVVGNGWYFRDLGEVLLWRQHNALVGGEKVWQAARRAEPGYRVA
                     NVCWWYAMGADVDWTVTPRPVYHADGRKEPDCWTDPPRLRDTLTEALGTFPLFSYWGPG
                     AGLPSSAWISRAAQRILADHAPDLPLVYLPHLDYDLQRFGPSGPEAAAAAAELDTVLGP
                     LLDAARDRDATVVALSEYGITDVSRPVDVNRLLRAEGLLRVYTQAGMEHLDPWTSRAFA
                     VADHQVAHVYVRDPADVPAVAKLCAALPGVAEVLDAAGQAGYGLDHPRSGELVLVAEPD
                     AWFTYYYWLDDARAPDFARLVEIHRKPGYDPAELFFDPAAPGAAKRRAAVALARKKLGL
                     RYLMNVVGLDAGARAVRGSHGRLPADPADGPVLLCSDRAAIRPRVEATDVKALLLELAG
                     LAWEAP"
     gene            complement(12456..13703)
                     /gene="eboE"
                     /locus_tag="MicB006_RS18870"
                     /old_locus_tag="MicB006_3799"
     CDS             complement(12456..13703)
                     /codon_start=1
                     /gene="eboE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783818.1"
                     /locus_tag="MicB006_RS18870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3799"
                     /product="metabolite traffic protein EboE"
                     /protein_id="WP_225980416.1"
                     /transl_table=11
                     /translation="MRLRHADGTTVHLGYCTNVHPAEDLPGIVAQLDTYAVAVRRALDA
                     DLLGLGLWLAAPVAAALAADPAARRRLRHELTVRGLEVVTLNGFPYAAFQAPVVKGAVY
                     HPDWTTPQRSAYTLDLARVLADLLPDDAVHGSVSTLPLAWRTPWDAARTATARRRLDAL
                     ADGLAAVQRETGRVIRVGFEPEPGCLVESTGQAREVFSTMDTDRLGICLDLAHLACAWE
                     QPADALAGLRAAGLPVVKVQVSAAVEAPDPVTAGAALRRFVEPRFLHQTRAAGCAGAAD
                     PADPAYAADDLDAALDARLPGAWRVHYHVPLHAPPEPPLRSTVPVLREALAALFAGPAA
                     GCDHLDVETYTWGVLPEARRPRGDAELAAGIAAEVAFARDELTALGLAPTAGVAVSARS
                     EPVLRAPHSRTKAGTA"
     gene            complement(13703..14554)
                     /locus_tag="MicB006_RS18875"
                     /old_locus_tag="MicB006_3800"
     CDS             complement(13703..14554)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475568.1"
                     /locus_tag="MicB006_RS18875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3800"
                     /product="TatD family hydrolase"
                     /protein_id="WP_116507868.1"
                     /transl_table=11
                     /translation="MRIFDPHIHMTSRTTDDYERMAAAGLRAVVEPAFWLGQPRTSVDS
                     FVDYFDSLIGWEPFRAGQFGVRHHATVALNPKEANDPRCRPVLDLLPRYLDKDGVVAVG
                     EIGYDAMTPAEDAALAGQLALAVAYDLPALVHTPHRDKARGVRRTLDVVAESDIAPERV
                     LVDHLNEVTVELVRDTGCWLGFSIYPETKMSPPRMVELLKRYGTERMLVNSAADWGRSD
                     PLLTRATGEAMQLAGFSADDVDRVLWRNPVEFYGQSGRLDLTALEANDPTFAGNSIARG
                     GE"
     gene            complement(14556..15161)
                     /locus_tag="MicB006_RS18880"
                     /old_locus_tag="MicB006_3801"
     CDS             complement(14556..15161)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475567.1"
                     /locus_tag="MicB006_RS18880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3801"
                     /product="EboA domain-containing protein"
                     /protein_id="WP_116507870.1"
                     /transl_table=11
                     /translation="MTPDRLRAALRGVPDPQWLDAALRRVATEPTAIERFFATAPRRCG
                     RGPLPDPPGWTADEAARALLLTTLPGGHAAAAETLYRQGDGAEKRAVLRALPLLPIGAE
                     CVPLLHDAIRTNDTRLVAAALGPYARHLEQPAWRQAVLKCVFTGVPLAVVDSLADRADG
                     ELARMLAAFAAERHAAGRTMPDDAADLLRRLTIPTTEA"
     gene            complement(15196..16074)
                     /locus_tag="MicB006_RS18885"
                     /old_locus_tag="MicB006_3802"
     CDS             complement(15196..16074)
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287906.1"
                     /locus_tag="MicB006_RS18885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3802"
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="WP_116507872.1"
                     /transl_table=11
                     /translation="MTAVPDPLSGPGALRFGYGTNGFANHRLGDALAVLADLGYQGVAL
                     TLDHDHLDPFAPGLIRRVAAVRRRLDALGLAVVVETGARYLLDPRHKHAPTLLHDDPAR
                     RVEFLRRAVRIGAELGAEAVSFWAGVRPPGVPPDVAADRLVAGCATVCAEAADEGVTLG
                     FEPEPDMFVEDIAGWWRLREALGAPPGFGITLDIGHCRCLEPLPVPQCVSEVAEHLVNV
                     QIDDMRRGVHEHLEFGAGEIDFPPVLRALADAGYRGLVAVELPRHSHAAPAVAARSLDF
                     LRAAASRGEGR"
     gene            complement(16071..16958)
                     /locus_tag="MicB006_RS18890"
                     /old_locus_tag="MicB006_3803"
     CDS             complement(16071..16958)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475565.1"
                     /locus_tag="MicB006_RS18890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3803"
                     /product="SCO3242 family prenyltransferase"
                     /protein_id="WP_116507874.1"
                     /transl_table=11
                     /translation="MTRLADLAELVRAPAALSVPGDVLSGAAAAGALDRRAPALAGASV
                     LLYWAGMAANDWADRRLDAVERPERPIPSGRVRPSVALGVASGLTAAGLAVATAAGGRR
                     AAAVALPLAATIWGYDLRAKNTAAGPAVMAACRGLDVLLGASGGRVVRALPAALTVAAH
                     TWTVTALSRREVTGADRRLPGLTLAGTALIALATPARPTPPAATARSGSGRLGHLVPAV
                     LAAGYAARYGRAQVRVLADPSPARVRAAVGAGITGLPALQGALTARAGARLLGLAVAGA
                     APLGRRLARLISPT"
     gene            complement(16955..18103)
                     /locus_tag="MicB006_RS18895"
                     /old_locus_tag="MicB006_3804"
     CDS             complement(16955..18103)
                     /GO_function="GO:0004512 - inositol-3-phosphate synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006021 - inositol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475564.1"
                     /locus_tag="MicB006_RS18895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3804"
                     /product="inositol-3-phosphate synthase"
                     /protein_id="WP_116507876.1"
                     /transl_table=11
                     /translation="MRTGVWLVGARGSVATTAMVGGLALRAGLTAPTGCVTELPALRGP
                     ALPGFADLVFGGHDVVATPLTKRAEALAAAGVLPGRLADAVAPDLAAVEAALRPAPVEG
                     DQGERIATVVRDLTEFRTRHGLDRVVVVNVAATEPAPAPHPAHSDLATLREALTSAADV
                     LPPSSAYAYAAFTAGCPYVDFTPSTGARLPALAALAAERGLPYAGHDGKTGETLLKSVL
                     APMFAMRHLAVRSWSGTNLLGGGDGATLADPAANAAKVGSKQRVLAETLGYLPQGGTRI
                     EYVEELGDFKTAWDLVTFAGFLGTGMRMEFTWHGCDSALAAPLVLDLARLTAAAHAAGR
                     HGPLTELAFFFKDPLGATGHALGEQWTVLRDFTAGLHARMSQ"
     gene            complement(18313..19485)
                     /locus_tag="MicB006_RS18900"
                     /old_locus_tag="MicB006_3805"
     CDS             complement(18313..19485)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018783812.1"
                     /locus_tag="MicB006_RS18900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3805"
                     /product="Gfo/Idh/MocA family protein"
                     /protein_id="WP_370013497.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2.4e-24, bitscore:
                     84.8, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 6.5e-31,
                     bitscore: 105.4, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGYAFMGAAHSQAWRTVNRVFDLPARVRMALVCGRDEPKVAEAA
                     DRLGWDGYTTDWRRLVESDEIDVVDICTPGDSHREIALAALAAGKHVLCEKPLANSVAE
                     AREMTEAAARARASGVRAMCGFNYRRVPAVALMRQLVADGRIGEIRHVRAVYLQDWIVD
                     PQFPLVWRLQKDRAGSGALGDIGAHIIDLTQFVTGQLITGVSALTETFVRQRPLVAGSS
                     GLAAQADGNGSATGQVTVDDAAVFVARLDGGALATYEATRFATGRKNALRVEINGSRGS
                     VVFDLERLNELEFLDATRPAAEQGFSRILVTEPDHPYLGAWWPPGHIIGYEHSFTHQAR
                     DFVEAVATGADPAPSFADALQVQLVLDAVTRSAERAAWTEVEPALAEASA"
     gene            complement(19539..20591)
                     /locus_tag="MicB006_RS18905"
                     /old_locus_tag="MicB006_3806"
     CDS             complement(19539..20591)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287910.1"
                     /locus_tag="MicB006_RS18905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3806"
                     /product="substrate-binding domain-containing protein"
                     /protein_id="WP_073831219.1"
                     /transl_table=11
                     /translation="MRTPRHDLSRRRLLFGGAAVSAGVLLAGCTSNEQSPTEAQTKAAG
                     SGANTEPGKKVTIGFSAPAADHGWIAAITNNAKAQAGAYQDVELKSVEAGADAAAQRAA
                     LSTLISQKPDVIVLLPHDGKELNAFGLEAMKAGIPVVNLDRAFPDARAYRCQIKGDNYG
                     MGVAAATYIAEQLKAKGVSNPVIGEIPGIESLELTQERSKGFADTLASYGFKVANRRPA
                     EFTVDSGQQAATGLFQALPKIDAVWNHDDDQGIGVLAAVNQANRKEFIMVGGAGSKKAM
                     EDIAADNTVLKATVTYSPSMASSAISLARLIGQGKGMSDLVELQVPKEIVLASETITKE
                     NASDYLKLGF"
     misc_feature    complement(20840..20854)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.71"
                     /tool="antismash"
ORIGIN
        1 cgcgcggtgc cctggctggt gaagatggtg gcggggctgc cggtgccggc cggaaagtgc
       61 ctgtcgatga cctcctgccc ggccaccgag tcggtgcgct gggtgaacag ctgggactgg
      121 ccgagcgtgg tggcgccgag ctgggtcacc ccgatcgcga gcacggcaag cgcgacagcg
      181 gtgacgatcc agacggtacg cgagcggcgc gccacgaagc cggcgatccg cgcccagatg
      241 ccgtgctcgg cgcgcgggtc ggcctcgtcg tgccggggcc gccggggcca gaacgcccac
      301 ctgccgccga ggaccagcag cgcgggcagg aacgtgagca tcaccagcag cgtggcggcg
      361 atgccgacgg cgctcaccgg gccgagcgcc cggttggagt tgaggctgga cagcagcagg
      421 cagagcaggc tgacgatgac tgtggcgccg gaggcgacga tggccggcgc ggcgcccttc
      481 caggcggtcc tcatcgcgtc ccagggccgc tcgtgccggt gcagctcctc ccggtagcgg
      541 gcgatgagca gcagcgcgta gtcggtgccg gcgccgaaca cgagcactgt gaggatgccc
      601 tgcgcctgcc cgttgagctt gacgatgtcg tggtcggcga gcaggtagac gaagacggcc
      661 gccagcgagt acgacatccc ggcggccagc agcgggaaga tccacagcac cgggctgcgg
      721 tagacgacga ggaggatgac caggaccacg gtgagggtga cgagcagcag cggcccgtcg
      781 atcgcgccga acacctcgat caggtcgccg agcagccctg cgggtccggc cacgtcgacg
      841 gtgagcccgt cgcggtccgg gccggcgatg tcgcgcaggc gttccaccac cgcgcggatc
      901 tgttcgccct caccgctttc gatcgggacg atcacctggg cggcctgccg gtcctggctg
      961 acgatcggtg gcggcagcgg gccgaccacg ccgggcacgt cggcgaagcg ggcggcgtcg
     1021 gcctggatcc gttgctggtc ggccggggtg aggccgccgg cgcgttcgta gaccacgagc
     1081 gccggggtgg tctcccggtc gacgaatccg gcggccaggt cctgcgcgcg ggtggcctcg
     1141 gcgtcggccg gcaggaagga ggcgttgtcg tttgtggaga cctcgccgag cttgcccgag
     1201 tacggcccgg cgacgccgcc gatgatcagc cagccgagca ccaccgccac cgcgacgagc
     1261 gtcgcggtcc agcggctgcg tcctgcggcc atctccaccg tcctcggatc gacgcatcaa
     1321 tcgacgcagc gggagtctag gtcgacgccg accatcctgc cgggcgaacg gtgactcggg
     1381 ggcggaaacc gggcagccgg gacacgcgag gggcgggaac gacgaacgcc cgtcggcggg
     1441 gccgacgggc gtgacatgga gcgaagctcc cccgattgga ctcgaaccaa taacctgccg
     1501 gttaacagcc ggctgctctg ccaattgagc tacaggggac cgtgcaccgc ccggatcgga
     1561 tctttccgct ccgtgcgacg gggacaagag tacaggacat ccgggggtgg tgcgccaggg
     1621 ggttaccgga ccggacccga ccggcggacg cgccagaatt acggacaaat cgtcatctcg
     1681 gcacagggag gcatgagcag agagcaggat gggtagttag ccgtcgacag agaagcaggc
     1741 gcgagatggt cgttccgccg agccggcgga aatcggcaaa gagcgtcagg tacggaagga
     1801 gccgccatgc gcggaaagat catgtttctt ggcgggctgg ctgcgggatt cgtcctgggc
     1861 gcccgtgccg gccgggagaa gtacgaagag ctggtggtcc gcgggcgcaa ggtcctcgac
     1921 cacccgaccg tccaggaggc ggccggggtc gcgcaggcgc aggcgacccg gctctactcc
     1981 gagggcaagg acaagctggg gcagaccaag ctgggtgaga agctcgccac cggcaacggc
     2041 ggcaagccgg gcatgaccga ggccgacaag ccgttcgcgg gcacgccggc agccgtcggc
     2101 agccgcgcca acggcacggg ctcgaccagc tcgaccagca cgtccggctc gaccacgacc
     2161 ggcacgagca ccaagccgtc caccggcaac acgctctgac gcaagcggac agcgggccgg
     2221 tcaccttcgg gtgaccggcc cgctcccgtg tgcccgggcg ccgatgtggc acattctcgg
     2281 tggggaggtg accacatgcc gatggtcgga ccggagacgg cggatcaggc acggctgctg
     2341 cgcctgctgc gtgacgacgg cccacggtcc cgggtcgagc tgaccgacct cctcggcctg
     2401 ccccgggccc ggttcgccgc cgaggcggac cggttgacag cgctgggcct ggtggagagc
     2461 gccggcccgg ccgcctcacg gggcgggcga cggtcgtcgc tgctgcgcat cggcgcgcag
     2521 gtccggttcg gcgcggtgct cgtcggcggc ggcacgctgc gggtcgcgct caccgacggc
     2581 gagctgaacc cgctggcccg ccacgacgag ccggtggacg tccggctcgg cccggacgtg
     2641 gtggtcgggc gcatggtcga gctgctcggc aagctgcgcg tcgaggcggg actgacgtcg
     2701 ctgaccggcg tcggtgtcgc gctgcccgcg ccggtcgagg tccgcgacgg cacgccggtc
     2761 tccccgccgg ccctgcccgg ctggcaccgc ttcccggtac gcgacacgct cgccgccgag
     2821 ctgggctgcc cggtgcaggt cgacaacgac gccaacgcga tggccctcgg cgaacggcac
     2881 gccggcaccg gccgcccgtt cgacgacttc ctcgccgtca agctgggcga cgcggtcggc
     2941 tgcgggctgg tgctcgccgg ttcgctctac cggggtgcgg ccagtggggc cggcgacatc
     3001 ggtcacctcc agctcagcga ggacgggccg ctctgcggct gcggccacaa cgggtgcgtc
     3061 gaggcgtact gcggggatgc cgcgctggtg cgggaggcgg tgacggccgc gcgggccggg
     3121 cgctcgacgg tgctcgcgga ccggctggcc gaggccggga cgctgtcggt ggcggacgtg
     3181 gcggcggcgg ccaccgaggg cgacccggcg gcgcaggtca tcgtccgcga cgccgcccgc
     3241 cgcctcgggc aggtgctggt cgggctggtc agcttcgtca acccggccat cgtcatcatc
     3301 gggggcgcgc cggccgggat cgggccggtc ctgctcgccg agatccgggg cgtggtctac
     3361 cggcgttcca cgccgctggc caccggcagc ctgccgatcg tcctgtccga cctaggcgac
     3421 accgccgccc tgatcggcgc agcccacctg gtgagcgacc aggcctacgc cgcccgctaa
     3481 ccccaccccc gccccaccct cacccccgcc tcccgccccg ccgatcttgc agttgcggcc
     3541 cgcaggatgt cggttacacc cgttttggga gggccgcaac tgcaagatcg cgggcgcaag
     3601 gagggaaggg cggggcggcg gggagggcgg gtcagtcgcg gctgctgaag gcggcgtcga
     3661 aggccgctga cggggcgtcg aacgccaggc ggcggacgaa ctggagcgcc tccggcgcgc
     3721 cgaccaggcg gtccatgccg gcgtcctccc actcgatcga gatcgggccg tcgtagccga
     3781 tcgcgttcag cgcccggaag cagtcctccc acggcacgtc accgtgcccg gtggagacga
     3841 agtcccagcc gcgtcgcagg tcggcccagg gcaggtggga ggagagccgg ccgcgccgcc
     3901 cgtccccggt acggaccttc gcgtccttgc agtcgacgtg atagatccgg tcggcgaagt
     3961 cgaagatgaa gttcaccggg tccagctcct gccagacgaa gtgcgacggg tcccagttga
     4021 gcccgaacgc gggccggtgc ccgatcgcct ccagcgtccg cttcgtggtc cagtagtcgt
     4081 acgcgatctc gctggggtgc acctcgtgcg cgaaccgcac gcccacctcg tcgaagacgt
     4141 ccaggatcgg gttccaccgg tcggcgaagt cctgatagcc gcgctcgatc atggcgggcg
     4201 gcaccggcgg gaacatggcc accgtgtgcc agatggacga gccggtgaag ccgacgacag
     4261 tgcgtacacc gagcttcgcc gccgcccgcg cggtgtcctt gatctcctcg gaagcccggc
     4321 ggcgcacgcc ctccggctcg ccgtcgcccc agatccgggc cgggaggatg tcctggtgcc
     4381 gctcgtcgat cgggtggtcg cagacggcct gcccgaccag gtggttggag atggcgaaca
     4441 cctggaggtt gtgcttggcc agggtggccc gcttgcgctc gacgtacgag tcgtcggcga
     4501 gcgccttgtc cacctcgaag tggtcgcccc agcaggcgat ctccagtccg tcgtagcccc
     4561 actcggcggc gagccggcag acctcgtcga acggaaggtc ggcccactgg ccggtgaaga
     4621 gcgtgatggg tcgcgccatt gtccttctcc cctgtggtga tgggggattc cgtcgcggac
     4681 cggggcgagg acgaccggag gcggcggcct gagggcaccg gtggacgccg gagcgtctgc
     4741 ctcccgggcg ggttgcgcct cccgccgggt caccggccac ctcgcggtcg ccgcctccac
     4801 tctacggcct tcctcagggc agggtccagc gctggttcgc cgcgcccgtg cacgtccaca
     4861 ggtgcaccgc cgtgccgtcg gccgagttgt tgcccgacac gtccaggcac ttgcccgacg
     4921 acggattacg cagcgtcccg tccgcctgcg ccgaccagtt ctgcgcaccc gtgccgttgc
     4981 acgaccacaa ctggatcttc gtgccgttcg cgttgccgcc gccggagacg tccaggcact
     5041 tgcccagcgc cttcaccggc ccgttcgacg tcaccgtcca cgtctgcgcc gacgagccgt
     5101 tgcaggtgta gagctggatc tgggtgccgt ccgccgacga ggcgttccgc acgtccaggc
     5161 acttgccggc cagccccttg atcgggccgg tgccgccgct gccggtcgag cggaccagcg
     5221 tgaagtcgtc cacgtcgaac agcccggagc cgctgccggt gaacgtcagg tgcacggtct
     5281 gcgtaccgga cggcacgcct gtgagcgcgg tcgacacgtc ggcgaacgtg gtccagctac
     5341 cggtgttcgg caccgccacc tggccgagca ccggcccggt cggcgagccg gtacgcacct
     5401 ggagcgtgcc gcccgggccg ccggagacca cccgggcgcg cagcgacgtc acaccggtga
     5461 ggtcgagccc cgggtacgcg gcccagtcgc ctgggtccac gtaccccagg gtctggccgc
     5521 cgttggcgcc cgccttgggg tacgcgctga cgccgctggc cgaaccgaac gactcggcct
     5581 ggaccgtggt gttgccggtc ggcggcggcg tcccgcccag ctccttgatc cggatgttgc
     5641 ggaacgacac gtcgtcgccg gtgccgtggt tctggatgcc gacgtgcccg gcgagcgacc
     5701 gcaccgggtc ggtgttggtg aagtcgttta tgcgtacgcc gttgaggaag acctgcagcc
     5761 gctcggactc gaccaggatc tcgtaggtgt tccactcccc cgccgggttc agcgccgcgt
     5821 cccgggccgc caggtccgcc gacttgaagc cgtagatcgc gccggtggtc cggtcggccg
     5881 cgtcggtggg gtcgatctgc acctcgtagc cgttgtccac agccgagttc gggtcgctcg
     5941 acggcgggaa gccgacgaac acgcccgagt tgtcgtcgcc ggccagccgc cagtccagct
     6001 tcagcgagta gttggtgaac tgcttcgcgc tgtaccagta caggcccatg ccgcccaccg
     6061 aggtgagcgt ggcgtcggcg ttggtgaagc tgcctggccc ggcctgggac cagccggtgg
     6121 tgccgccgtt gtagagcgcg gtgtagccgg tctccggccg gcagtcggcc ttcgtgcgcc
     6181 cggccgcgta gcggatgccg ccgagcaggt ggttgcggaa cgccgcgtcg gcgtaggacg
     6241 cctgggtgtg gccgccgccg gtgtagaagg accggccacc gctgtacgtc ttgcaccagg
     6301 cgtgcgggtg gtcgccgccc atcgagcctc cggagtacga ggactcgtcg aggctggcca
     6361 gcacgtgcgc ggtggagcgg gcgttggagc ggtagtcgta ccactcgtcg gtgcggttcc
     6421 actgctgcgg caggtgcgcg gtggccgcgt gtgcccggtc ctccaccttg acggtggccg
     6481 gctggatggc cgggtgggag gcgaaccagg cgccgacgag gttgccgtag aacggccagt
     6541 cgtactcggt gtcggcggcg gagtgcacgc cgacgtaccc gccgccggcg ccgatgtacg
     6601 cctcgaacgc cgactgctgg gtggcgttga ggacgtcccc ggtggtgttg aggaagatca
     6661 ccgcctcgaa gcgggccagg ttggcggtgg tgaactgggc ggcgtcctcg gtcgcggtga
     6721 ccgtgaagtt gttcgccgtg cccagctcgc gcacggcctg cgtgcccgcc gcgatggagt
     6781 cgtggcggaa tccggcggtc ttggagaaga cgagtacgtc gtagggggcg tcggcggcgg
     6841 cggccgggcc cgcggggacg gtgcaggcga tggcggtgag gacggcggtc accgccccca
     6901 gtgcggtacg caggagtttc atctggttct ccttcatcct cagggcaggg tccagcgctg
     6961 gttcgccgcg ccggtgcacg tccacaggtg caccgccgtg ccgtcggccg agttgttgcc
     7021 ggacacgtcc aggcacttgg ccgacgacgg gttgcgcagc gttccgtccg cctgcgccga
     7081 ccagttctgg gcgccggtgc cgttgcacgt gtacagctgg atcttggtgc cgtccgcgct
     7141 ggcgccaccg gagacgtcca ggcacttgcc gagcgccttc accgtggcgt tcggcgtcac
     7201 cgtccacgac tgcgccgtcg tgccgttgca ggtgtagagc tggatctgcg tgccgtcggc
     7261 ggtggcggcg ttgcgcacgt ccaggcactt gccggccagg cccttcaccg ggccggtgcg
     7321 cacggccggc gtggtgagcg tgaacgcgtc caggtcgtag agcgccccgc tgcccccggc
     7381 gaacgtgagg tagagcgtgg tggtgccggc cggcgggctg gtgatcgtgc cggtcactgt
     7441 ggtgaacgtg tcccaggcgc cggtgaccgg gacggtggcg gagccgagga cggcgccggt
     7501 ggccgagccg gcccgcacct ggagcgtgcc gccggctccg gcggacgaga cccgggcggt
     7561 gaatccggtg gcgtcggcga gcaggtacgg ccggaacgcg atccagtccc cgttgtggat
     7621 gtcgccgacg gtcctgccgc cctcggcggt gcccttgtcg aacgtgttga ccccggcgga
     7681 ggtggcgaag tgctcggcct gccggtgccg gggctggagc gtgtgctggg tgtgcgtggt
     7741 gaggccgccg gagtcggtgt actcggcgtc gaagaccgcg aagatgttcg ccgcgtcgtc
     7801 gtgctcaccg tcgaccggca cggcgatcga gccggtgcag ccggtcgccg aggtgatctg
     7861 gtggccgtgc tggtcgtggc cgagcacgta ggtcatcttg accttcgtgc agtcgatggt
     7921 ggcgtcctcc gggtcggtga cggtgatccg gaacggcacc gtgtcgccga aggagaacag
     7981 cttgccgttg ccgggcgtct cgatgaccac agtcggggcg gtgttgccga ctgtgactgt
     8041 cacgctcgcg gtgccggtgg cgccctgcgg gtcgcgcacg gtgagcgtgg cggtgtacct
     8101 gccgttcgcg gtgtaggtgt gcgaggggtt cgccgcggtg gaggtgccgc cgtcgccgaa
     8161 cgtccaggcg tacgtgagcg cgccgccctc cgggtcggac gagccggccg aggagaacgc
     8221 gactgcgagc ggcgcggcgc cggatgtccg gtcggcggcg gcacgggcca ccggggcacg
     8281 gttggcgccg cccaggtagt cgaagcggta cagcgccgag ttggcgtcgc cgttgaagta
     8341 gccggtgccg tagtcgagca cgtagtacgc gccgtccggg ccgaacgcgg agtccatcac
     8401 ctgtttgccg gcccacggga acgtgtcgat ggtgccgggt gagccgtcgg cgttgacgtg
     8461 gatcggcttg atccagcccc ggccgaactc ggtggcgaag aactgcccgt cgaaggactg
     8521 cgggaacttc gtggtggacg ggttcgccgc gtcgtaccgg tagaccgggc cgcccatcgg
     8581 cgactcggag ccgccgccga actcgggcgg gctgcccgcg tcaccggcgt agcggatcca
     8641 ggacggcttc gccgccggca acgtggccag gccggtgttg cggaacgagt tgttcgtcgg
     8701 gccgccggtg cagttgtact tcggcccggc ggtgccggtg gcgaagtccc attcggcgta
     8761 cgtctcggcg gccgtgttgg tgccggtgca gtacggccag ccgtagttac cggggccggt
     8821 gacccggttg aactcgacct gcccggacgg gccgcgggcc gtggtggtgc cggcgtccgg
     8881 cccgtagtcg cccacgtaga ccacgccggt ggccttgtcg acgctgatcc ggaacgggtt
     8941 gcggaagccc atcgcgtaga tctccgggcg ggtccgcgcg gtgccgggcg cgaagaggtt
     9001 cccggccggg atcgagtacg tgccgttggc gttcaccttg atccgcagga tcttgccgcg
     9061 caggtcgttg gtgttgccgg cgctgcgctg cgcgtcgtac ccggggttgc ggttggtgcg
     9121 ctcgtcgatc ggcgcgtagc cggccgagtc gaacgggttg gtgtcgtcgc cggtggacag
     9181 gtagaggttg ccggcggcgt cgaagtcgat gtcgccgccg acgtggcagc acagcccccg
     9241 gtcggccggt acgtcgagca cgtcgacctt gctggcctgg ttgagcgtga agtcggcgtt
     9301 gagcgtgaac cgggagagcc ggttgacgcc ctgccaggcg gagaagtcgg tgccggtggc
     9361 gggcgcgtcc ccggccgggg tggacagcgg cggcgcgtag tagaggtaga tgtgccggtt
     9421 ggaggcgaag ccggggtcga cgccgacgcc ctgcagcccc tcctcgtcgt gggtgtagac
     9481 cggcagcgtg ccgatgaccg tggtggcgcc ggccgcgtcg gtgcggcgca gcgtgccgtt
     9541 gcgggcggtg tgcaggaccg accggtcggg cagcaccgcc agggacatag gttcgccggt
     9601 ctcggcgacg ccgcgggcga gttcgacctg ctggaagtcg ctcgccgtga tggggtgggc
     9661 ggacgccggg acgggcgccg cggccgctgt gacggtgccg gcggtggccg cgagcagcag
     9721 cgctgctgcg gcggcgagcg gtcgtcgggc acgggggtgg tggtggctgg acatgctgtg
     9781 ctgtcccttc ctgacgcgcg cagccaggac cgggcgcgcg tcgcgccgga tgccgagcgg
     9841 gggatgctgc gcctcgccga ggcgggcggt gcggggcggg gcgggtcgcc tcgacgagac
     9901 agctaggtgc tgtgcacgac attaaaacct ttcgatcagt ctgtccatag cttctgatcg
     9961 atcggcttac actttcgccg ctacgcgaca aaagtaggtg tcactcgcgg cggtcgacgg
    10021 cccgttccac gagcgcggcg agcacccggc gggccggctc cgcgagcccc gccgcgtcca
    10081 gcgcgaccac tgccgcctcg gcccgggtcc ggatcatccg ctccaccgcc tcccgggcgc
    10141 cggactcctc gacgatgccc cgcacctcgg ccgcgcccgc ctgatccagc gccggatcgc
    10201 cgaccagctc ccgcagccgg gccacgccgg ccggggaggc ggacgcccgg gccagcgcca
    10261 gcagcaccgt cggcttgccc tcgcgcaggt cgtccaggtt ggacttgccg gtcaccgccg
    10321 gatcgccgaa gacgccgagg acgtcgtcgc ggagctggaa cgcgtccccg agcgggtcgc
    10381 cgaacccggc gagcgccgcc acctcctccg gcgtcgcgcc ggccagcgcg gcgccgatct
    10441 gcaccggacg ggtcaccgtg taacgggccg tcttcagccg caccacggcg agcgcgctgg
    10501 ccaccgagcc gtccccggcc gccgcgacca cgtccaggta ctcccccgcg atcacctcgg
    10561 agcgcatccg cgccagcagg acgtgccccc ggcgcagccg ctccggcggc aacccgcagc
    10621 cgtggaacat ctgcgccgac caggtggcgc agaggtcccc gcagagcacc gccgcctgcc
    10681 ggccgtacgc cgccggatca ccgcgccagc cggaccgctc gtgcaggccg gcgaagaagc
    10741 ggtgcagcgt cggcgcgccc cggcgacggt cactgcggtc cacgatgtcg tcgtggatca
    10801 gcgcgaacgc gtggaacaac tccagcgacg ccgcggccac cacgatcggc cgctcgtccg
    10861 ggccgccgaa accccgccag ccccagtagc agaacagcgg tcgcatccgc ttgccaccgg
    10921 ccagcacgaa ccggcgcaga gcggtgtgga cggcccccgt accgtcgtcc ggccgacccg
    10981 gccgtctcgc gtccaggaac gcggcgagct cggcgtcgaa gcggccccga agcagggccg
    11041 ggtcggtcgg tgcgacggtt acggtcatgg tgcctcccag gccaatccgg cgagttcgag
    11101 caacaacgcc ttcacatcgg tcgcctccac ccggggccgg atcgcggccc ggtcggagca
    11161 gagcagcacc gggccgtccg ccggatcggc cggcaggcgc ccgtgcgaac cacgcaccgc
    11221 ccgcgccccg gcgtccagcc cgaccacgtt catcagatag cgcaggccga gcttcttgcg
    11281 ggccagcgcc accgccgcgc ggcgtttcgc cgcgcccgga gcggccgggt cgaagaacag
    11341 ctcggccggg tcgtaacccg gcttgcgatg gatctccacc agccgggcga agtcgggcgc
    11401 ccgcgcgtcg tcgagccagt agtagtaggt gaaccaggcg tccggctcgg ccaccagcac
    11461 cagctcgccc gagcggggat ggtcgaggcc gtacccggcc tgcccggcgg catcaagcac
    11521 ctcggccacg ccgggcagcg ccgcgcagag cttcgccacc gccggcacgt ccgccggatc
    11581 ccggacgtag acgtgcgcca cctggtggtc ggccaccgcg aacgcccgtg acgtccacgg
    11641 gtcgaggtgt tccatgccgg cctgggtgta gacccgcagc aacccttcgg cgcgcagcaa
    11701 ccggttcacg tccaccgggc gggacacgtc agtgatgccg tactcggaca acgccacaac
    11761 agtagcgtcc cgatcacggg cggcatccag cagcgggccg agcaccgtgt ccaactcggc
    11821 cgccgcggcg gcggcctccg gcccggacgg accgaagcgt tgcaggtcgt agtccagatg
    11881 cggcaggtac accagcggca ggtcgggggc gtggtcggcg aggatgcgct gcgccgcccg
    11941 gctgatccac gccgaggacg gcagcccggc accaggcccc cagtagctga acagcgggaa
    12001 cgtgccgagc gcctcggtca gcgtgtcccg cagccgcggc gggtcggtcc agcagtccgg
    12061 ctccttgcgc ccgtcggcgt ggtagaccgg gcgcggcgtg acggtccagt ccacgtccgc
    12121 gcccatcgcg taccaccagc agacgttggc gacccggtag cccggctcgg cccggcgggc
    12181 cgcctgccac accttctcgc cgccgaccag cgcgttgtgc tgccgccaga gcagcacctc
    12241 gcccaggtcg cggaagtacc agccgttgcc caccacgccg tgcccggcgg gcagctcgcc
    12301 ggtgaggaac gtggactgcg ccgagcacgt caccgccggc agcacggtgc ccagctcggc
    12361 ggcgaacccg gcctcggcca ccgcgcgcag ccggggcatg tgcgccagca gccgcggggt
    12421 cagcccgacc acgtcgagca ccaccagccg ccggctcatg cggtgccggc cttcgttcgc
    12481 gaatgcgggg ctcgcaggac cggctcactc ctcgcgctca cggcgacccc cgccgtcggc
    12541 gccagcccga gcgcggtcag ctcgtcgcgg gcgaaggcca cctcggcggc gatgccggcg
    12601 gccagctccg cgtcgccgcg cggccgccgc gcctccggca gcacccccca ggtgtacgtc
    12661 tcgacgtcga ggtggtcgca gccggcggcc ggaccggcga acaacgcggc cagcgcctcc
    12721 cgcagcaccg gcaccgtgga gcgcaacggc ggctcgggcg gggcgtgcag cggcacgtgg
    12781 tagtgcaccc gccacgcccc gggcagccgc gcgtcgagcg cggcgtcgag gtcgtcggcc
    12841 gcgtacgccg gatcggccgg gtcggcggcg cccgcgcaac cggccgcgcg ggtctggtgc
    12901 aggaacctcg gctcgacgaa gcggcgcagc gccgcgcccg ccgtcaccgg gtcgggcgcc
    12961 tcgaccgcgg cggacacctg gaccttcacc accggcagcc cggcggcacg cagcccggcc
    13021 agggcatccg ccggctgctc ccaggcgcac gccaggtgtg cgaggtccag gcagatcccg
    13081 agccggtcgg tatccatggt tgagaatacc tcgcgtgctt gtcccgtcga ctccaccagg
    13141 cagccgggtt ccggctcgaa gccgacccgg atcacccggc cggtctcccg ctgcaccgcg
    13201 gccagcccgt cggccagcgc gtcgagccgc cgccgggcgg tcgcggtacg cgcggcgtcc
    13261 cacggcgtac gccaggccag cggcagtgtc gagaccgacc cgtggacggc gtcgtcgggc
    13321 agcaggtcgg ccagcacccg ggccaggtca agcgtgtacg ccgagcgctg cggcgtggtc
    13381 cagtccgggt ggtacaccgc gcccttgacc accggggcct ggaacgcggc gtacgggaaa
    13441 ccgttgagcg tgaccacctc cagacctcgt acggtcagct cgtggcgcag ccggcggcgg
    13501 gccgccgggt cggcggcgag cgcggcggcc accggcgcgg ccagccagag cccgagcccg
    13561 agcaggtcgg cgtcgagcgc ccggcgcacc gcgaccgcgt acgtgtcgag ctgggcgacg
    13621 atgccgggca ggtcctcggc cgggtggacg ttcgtgcagt agccgagatg aactgtcgtg
    13681 ccgtcggcgt ggcgcagccg catcattcgc ctccgcgcgc tatcgagttg ccggcgaatg
    13741 tggggtcgtt cgcctccagg gcggtcaggt cgagccggcc ggactggccg tagaactcaa
    13801 ccgggttgcg ccacagcacc cggtccacgt cgtcggcgct gaacccggcc agctgcatcg
    13861 cctccccggt ggcccgggtc agcagcgggt ccgatcgccc ccagtcggcg gccgagttga
    13921 ccagcatccg ctcggtcccg taccgcttca gcagctcgac catgcgcggc ggcgacatct
    13981 tcgtctccgg gtagatggag aagcccagcc agcagccggt gtcccggacc agctccaccg
    14041 tcacctcgtt gaggtggtcg acgagcaccc gttccggcgc gatgtccgac tcggcgacca
    14101 cgtcgagcgt gcgccgtacg ccgcgtgcct tgtcccggtg cggcgtgtgc accagggcgg
    14161 gcaggtcgta cgcgacggcc agcgcgagct gcccggccag cgcggcgtcc tcggccggcg
    14221 tcatcgcgtc gtagccgatc tcgccgaccg ccaccacgcc gtccttgtcc aggtagcggg
    14281 gcagcaggtc gagcaccgga cggcagcgcg ggtcgttcgc ctccttcggg ttcagcgcca
    14341 ctgtggcgtg gtgccggacg ccgaactgcc cggcccggaa cggctcccag ccgatcagcg
    14401 agtcgaagta gtccacgaag ctgtccacgc tcgtacgcgg ctggcccagc cagaacgccg
    14461 gctcgaccac cgcgcggagc ccggcggcgg ccatccgctc gtagtcgtcg gtggtgcggg
    14521 acgtcatgtg gatgtgcggg tcgaagatgc gcatgtcacg cctccgtggt ggggatggtc
    14581 agccggcgca gcaggtcggc cgcgtcgtcg ggcatggtcc ggccggcggc gtgccgctcg
    14641 gcggcgaacg cggcgagcat ccgcgccagc tcgccgtcgg cgcggtcggc caggctgtcg
    14701 accaccgcca gcggcacgcc ggtgaacacg cacttgagca ccgcctgccg ccaggccggc
    14761 tgctccaggt gccgggcgta cgggccgagc gcggcggcga ccagccgggt gtcgttggtg
    14821 cggatcgcgt cgtgcagcag cggcacgcac tccgccccga tgggcagcag cggcagcgcg
    14881 cgcagcacgg cgcgtttctc ggcgccgtcg ccctgccggt agagcgtctc cgccgcggcg
    14941 gcgtgaccgc ccggcagcgt tgtcagcagc agcgcccgcg ccgcctcgtc ggccgtccag
    15001 ccgggcgggt cgggcagcgg cccgcgaccg caccgccggg gggcggtggc gaagaaccgt
    15061 tcgatcgccg tgggttcggt agcgacgcgg cgcaacgccg cgtccagcca ctgcggatcg
    15121 ggtacgcccc gaagcgcggc gcgcagtcgg tcgggtgtca tgccgtctcc cctctgccgg
    15181 gtggaaggtg gtgggtcacc gcccctcgcc gcgcgaggcg gcggcgcgca ggaagtccag
    15241 tgagcgggcg gcgacggccg gggccgcgtg cgagtgccgg ggcagttcca ccgccaccag
    15301 cccgcggtag ccggcgtcgg ccagggcgcg cagcaccggc gggaagtcga tctcaccggc
    15361 gccgaactcc aggtgctcgt gcacgcctcg gcgcatgtcg tcgatctgca cgttgaccag
    15421 gtgctcggcg acctcggaca cgcactgcgg caccggcagc ggctccaggc agcggcagtg
    15481 gccgatgtcg agcgtgatgc cgaagccggg cggcgcgccg agcgcctcgc gcagccgcca
    15541 ccacccggcg atgtcctcga cgaacatgtc cggctccggc tcgaagccca gcgtcacgcc
    15601 ctcgtcggcg gcctcggcgc agacggtcgc gcagccggcc accaggcggt cggcggcgac
    15661 gtcgggcggt acgccgggcg ggcgtacgcc ggcccagaag gagaccgcct ccgcgcccag
    15721 ctcggcgccg atccgcacgg cccggcgcag gaactccacc cgccgggcgg ggtcgtcgtg
    15781 cagcagcgtc ggcgcgtgct tgtgccgggg gtcgagcagg tagcgggcgc cggtctcgac
    15841 caccaccgcc agcccgagcg cgtccagccg gcggcgtacg gcggccaccc ggcggatcag
    15901 cccgggggcg aacgggtcca gatggtcgtg gtcgagggtg agcgcgacgc cctggtagcc
    15961 gaggtcggcg aggaccgcca gcgcgtcgcc gaggcggtgg ttggcgaagc cgttggtgcc
    16021 gtacccgaaa cgcagcgcgc ccgggccgga cagcgggtcg ggcacagctg tcatgtcggc
    16081 gagatcagtc gggccaggcg gcggccgagc ggggcggccc cggccacggc gaggccgagc
    16141 agccgggccc cggcgcgggc ggtgagcgcg ccctgcaagg cgggcagccc ggtgatcccg
    16201 gccccgacgg ctgcgcgtac ccgggccggt gacgggtcgg cgagcacccg gacctgcgcc
    16261 cggccgtacc gggcggcgta ccccgccgcg agcaccgcgg gcacgaggtg accgagccgg
    16321 ccggaaccgc tgcgggccgt ggcggctggt ggcgtgggcc gggccggggt ggcgagcgcg
    16381 atcagcgcgg tgccggccag cgtgaggccg ggtagccgcc ggtccgcgcc ggtcacctcg
    16441 cggcgggaca gcgcggtcac ggtccaggtg tgcgcggcca ctgtgagcgc ggccggcagc
    16501 gcccggacca cccggccgcc ggacgcgccg agcagcacgt ccaaccctcg gcaggcggcc
    16561 atcaccgccg ggccggcggc ggtgttcttg gcgcgcaggt cgtaccccca gatcgtggcg
    16621 gcgagcggga gcgcgaccgc tgccgcccgg cggcccccgg cggcggtggc taccgcgagc
    16681 ccggcggcgg tcaggccgga cgcgacgccg agtgccaccg acgggcgcac ccggccggac
    16741 gggatcggcc gctccggccg ttcgacagcg tccagccgcc ggtccgccca gtcgttggcg
    16801 gccatcccgg cccagtagag cagcaccgac gcgccggcca gcgcgggcgc ccggcggtcg
    16861 agcgcaccgg ccgcggcggc gccggacagc acgtccccgg gcaccgacag cgcggcgggc
    16921 gcccggacca gctcggccag gtcggccagg cgggtcactg cgacatccgg gcgtgcaggc
    16981 cggcggtgaa gtcccgcagc accgtccact gctcgccgag cgcgtggccg gtcgcgccga
    17041 gcgggtcctt gaagaagaac gccagctcgg tcagcgggcc gtggcggccg gcggcgtgcg
    17101 cggcggcggt gagccgggcc aggtccagca cgagcggcgc ggcgagcgcc gagtcgcagc
    17161 cgtgccaggt gaactccatg cgcatgccgg tgcccaggaa accggcgaac gtgaccagat
    17221 cccaggcggt cttgaagtcg cccagctcct cgacgtactc gatccgggta ccgccctgcg
    17281 gcaggtagcc gagcgtctcg gcgagcaccc gctgcttgct gcccaccttc gcggcgttgg
    17341 cggccgggtc ggcgagcgtg gcgccgtcgc cgccgccgag caggttggtg ccggaccagg
    17401 agcgcacggc gaggtgccgc atcgcgaaca tcggcgcgag caccgacttg agcagcgtct
    17461 cgccggtctt gccgtcgtgc ccggcgtacg gcagtccgcg ttcggcggcg agcgcggcca
    17521 gggccggcag ccgggctccc gtggacgggg tgaagtccac gtacgggcag ccggcggtga
    17581 acgccgcgta cgcgtacgcg gaactgggcg gcagcacgtc ggccgcactg gtcagcgcct
    17641 cgcgcagcgt ggccaggtcg ctgtgggccg ggtgcggtgc gggcgccggc tcggtggcgg
    17701 cgacgttgac caccaccacc cggtccagcc cgtgccgggt gcgaaactcg gtcaggtcgc
    17761 ggaccacagt ggcgatccgc tccccctggt cgccctcgac cggcgcgggc cgtagcgccg
    17821 cctcgacggc ggccaggtcg ggcgccacgg cgtcggccag ccggccgggc agcaccccgg
    17881 cggcggcgag cgcctcggcg cgtttggtga gcggggtggc gaccacgtcg tggccgccga
    17941 agacgagatc ggcgaagccc ggcagggcgg gcccgcgcag ggcgggcagc tcggtcacgc
    18001 atccggtcgg cgcggtgagc ccggcccgca gggccagccc gccgaccatg gcggtggtgg
    18061 cgaccgagcc gcgcgcgccc accagccaca cacccgtacg cattcgcgct acctccccag
    18121 gtaaggccgg tccgccggtg cggccgggga atcccggtcc ggccgcaccg gagggccgtg
    18181 ctggtcgtgc cggcggacac cggcggcacg ctccccggag ccggcctcgt ccccgccgcg
    18241 gggcgcaacc gcggcgggcc ctcgccggcc ggcgccggtg agtgtcggcg gaccccgtgg
    18301 ggccgcctca ggtcaggcgg aagcttcggc cagcgcgggt tccacctccg tccaggcggc
    18361 ccgctcggcc gagcgggtca ccgcgtcgag cacgagctgg acctgcagcg cgtcggcgaa
    18421 cgacggagcc gggtcggcgc cggtggcgac cgcctcgacg aagtcacgcg cctggtgggt
    18481 gaaggagtgc tcgtagccga tgatgtggcc gggcggccac cacgcgccca ggtacggatg
    18541 gtccggctcg gtcaccagga tccggctgaa gccctgctcg gcggcgggcc gggtggcgtc
    18601 caggaactcc agctcgttga ggcgttccag gtcgaacacg acgctgccgc gcgaaccgtt
    18661 gatctcgacc cgcagcgcgt tcttacggcc ggtggcgaac cgggtcgcct cgtacgtggc
    18721 cagcgctccc ccgtcgagcc gggccacgaa caccgccgcg tcgtccactg tcacctggcc
    18781 tgtcgcgctg ccgttgccgt cggcctgcgc ggccaggccg ctcgacccgg cgacgagcgg
    18841 tcgctggcgc acgaacgtct cggtcagcgc gctgaccccg gtgatgagct gaccggtgac
    18901 gaactgggtc aggtcgatga tgtgcgcgcc gatgtcgccg agcgcgccgg agcccgccct
    18961 gtccttctgc aaccgccaca ccagcgggaa ctgcgggtcg acgatccagt cctggaggta
    19021 gaccgcccgg acgtgccgga tctcgccgat ccgcccgtcg gccaccagct gccgcatcag
    19081 ggcgaccgcc ggcacccgcc ggtagttgaa gccgcacatc gcgcgtaccc cggacgcccg
    19141 ggcccgggcc gcggcctcgg tcatctcccg ggcctcggcg acgctgttcg cgagcggctt
    19201 ctcgcacagc acgtgcttgc ccgcggcgag cgcggcgagc gctatctcgc ggtggctgtc
    19261 ccccggcgtg cagatgtcga ccacgtcgat ctcgtcggac tcgacgagcc gccgccagtc
    19321 ggtggtgtag ccgtcccagc cgagccggtc ggcggcctcg gccaccttcg gttcgtcccg
    19381 gccgcagacg agcgccatcc gcacccgggc cggcaggtcg aacacccggt tcacggtgcg
    19441 ccacgcctgg gagtgcgcgg cgcccatgaa cgcgtagccg accatgccga cccgcaggat
    19501 gctgtcgtga ctggacaagg tgggtctccc cccgtgtgtc agaacccgag cttcaggtag
    19561 tcgctcgcgt tctccttggt gatcgtctcg gaggcgagca cgatctcctt cggtacctgg
    19621 agttcgacca ggtcggacat gcccttgccc tggccgatca ggcgagccag ggagatcgcc
    19681 gaggaggcca tcgacgggct gtaggtgact gtggccttga ggaccgtgtt gtcggcggcg
    19741 atgtcctcca tggccttctt ggagccggcg ccgccgacca tgatgaattc cttgcggttg
    19801 gcctggttga ccgcggcgag cacgccgatg ccctggtcgt cgtcgtggtt ccagaccgcg
    19861 tcgatcttcg gcagcgcctg gaacaggccg gtggcggcct gctggccgga gtcgactgtg
    19921 aactccgccg gacgccggtt ggcgaccttg aacccgtacg aggcgagcgt gtcggcgaac
    19981 cccttcgacc gttcctgggt cagctccagc gactcgatgc cggggatctc accgatcacc
    20041 gggttgctca cgcccttggc cttgagctgc tcggcgatgt aggtggcggc ggccaccccc
    20101 atgccgtagt tgtcgccctt gatctggcac cggtaggcgc gcgcgtccgg gaaggcccgg
    20161 tccaggttca ccaccgggat gccggccttc atcgcctcca ggccgaacgc gttgagttcc
    20221 ttgccgtcgt gcggcagcag cacgatcacg tcgggcttct gcgagatcag cgtggacagc
    20281 gccgcccgct gggccgccgc gtccgcgccg gcctcgaccg acttcagctc cacgtcctgg
    20341 tacgccccgg cctgcgcctt ggcgttgttg gtgatggcgg cgatccagcc gtggtcggcg
    20401 gccggggcgg agaagccgat ggtcaccttc ttgcccggct cggtgttggc gccggaaccg
    20461 gccgccttgg tctgtgcctc ggtcgggctc tgctcgttgc ttgtgcagcc ggcgagcagc
    20521 accccggcgg agaccgcggc cccgccgaag agcagccggc ggcgggacag gtcatggcgc
    20581 ggtgttctca tgacgcctcc tgggatgagg tggtggggtg gtttcgggtg tggcgggccg
    20641 gaccaccgtc ggtacgacgg cagccggggt gtgcgcgggt ggggtcaggt ggtggtggtg
    20701 gcccggttgc gggcgaggag ctgggtgaga ctgccgaact gcacctgctg gaccaggacg
    20761 gcggcgacga tgatgccgcc cttgaccatg ttctgggcct cggcggagag gttgttgatg
    20821 gcgaacaggt tggtgatcgt ggagaagatg atcaccccga gcagggagcc gatgatcgtg
    20881 ccccgcccgc cgctgagcag cgtgccgccg atgatcgcgg cggcgatcgc gtccagctcg
    20941 tagaggttgg ccatcgccgc ctcggcggag gtggcctgcg cggtcagcat gaccgcggcg
    21001 atgccgcagc acaggccgga gagcgcgtag aggagcactg tgtgccggcg gacgttgatg
    21061 ccggccag
//
