LOCUS       NZ_CP030865            21083 bp    DNA     circular CON 14-AUG-2024
DEFINITION  Micromonospora sp. B006 chromosome, complete genome.
ACCESSION   NZ_CP030865
VERSION     NZ_CP030865.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sp. B006
  ORGANISM  Micromonospora sp. B006
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Complete Genome of Micromonospora sp. Strain B006 Reveals
            Biosynthetic Potential of a Lake Michigan Actinomycete
  JOURNAL   J Nat Prod 81 (9), 2057-2068 (2018)
   PUBMED   30110167
REFERENCE   2  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2018) Medicinal Chemistry and Pharmacognosy,
            University of Illinois at Chicago, 900 S Ashland Ave, Chicago, IL
            60607, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 77.6x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003408515.1-RS_2024_08_14
            Annotation Date                   :: 08/14/2024 03:31:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,342
            CDSs (total)                      :: 6,278
            Genes (coding)                    :: 6,199
            CDSs (with protein)               :: 6,199
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 20 of 79
            Pseudo Genes (incomplete)         :: 62 of 79
            Pseudo Genes (internal stop)      :: 6 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:07:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3919546
            Orig. end                         :: 3940629
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21083
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="17"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21083
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21083
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11083](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11083
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    150..164
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(354..860)
                     /locus_tag="MicB006_RS17365"
                     /old_locus_tag="MicB006_3495"
     CDS             complement(354..860)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785282.1"
                     /locus_tag="MicB006_RS17365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3495"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_116507487.1"
                     /transl_table=11
                     /translation="MPTSPAQAPTVPAHVLPHRTPAQLLAVARDGLAEAARTRPDGLRY
                     AAAHLAALRAAAAVLAARARPAPTRRNRITSVWVLLATVAPELDEWAVYFAAGASKRAA
                     AEAGIPRVVTAREADDLLRAAEEFVTVVETALGLAHQPALDGLPRPLRRGASDSPPSRP
                     GAAAA"
     misc_feature    complement(1255..1270)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.7"
                     /tool="antismash"
     misc_feature    1256..1269
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.82"
                     /tool="antismash"
     gene            1388..1876
                     /locus_tag="MicB006_RS17370"
                     /old_locus_tag="MicB006_3496"
     CDS             1388..1876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018742850.1"
                     /locus_tag="MicB006_RS17370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3496"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_116507489.1"
                     /transl_table=11
                     /translation="MQPHPNVQAVQRALDEAGARVGSGEASLVRLLPDAVHTAAAAAEA
                     LGVAVGAIANSLIFDADGAPLLVLTSGAHRVDTAGLAATLGVTRLRRATPEFVKRHTGQ
                     VIGGVAPVGHPAPLRTVVDTALTGYDEVWAAGGVPRAVFPTTYAELLRITAGAPAEVA"
     gene            1873..2601
                     /locus_tag="MicB006_RS17375"
                     /old_locus_tag="MicB006_3497"
     CDS             1873..2601
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287628.1"
                     /locus_tag="MicB006_RS17375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3497"
                     /product="monooxygenase"
                     /protein_id="WP_116507491.1"
                     /transl_table=11
                     /translation="MNPELVTLHVWRVPRRAVPGVLARMATHPARLRRLPGVRFAKLLG
                     TGTGTGFGPGDADLTRWAALVVWDSPADAAGFDASPVARSWARIARAAVRVDLRPLTSR
                     GRWSGREPFGAPSGGRVTGPVLALTRARLRTRRAATFWRAIPPVAAELHTAPGLLARFG
                     VGEAPLGWQGTVSVWRDPADLVAFAYRSPEHRAAITRTPTEGWYAEELFARFAVGDVAG
                     DRTVLGWAAEDDPETARGYA"
     gene            2598..3152
                     /locus_tag="MicB006_RS17380"
                     /old_locus_tag="MicB006_3498"
     CDS             2598..3152
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014456.1"
                     /locus_tag="MicB006_RS17380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3498"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_116507493.1"
                     /transl_table=11
                     /translation="MRLVRWTPDDLVRRLDDVVAVYGEAMGYRPDLLEARRGYIATHVR
                     RPGFRAVASLTSEGHLAGFGYGYRGATGQWWHDQVHRALNAQARQRWLTHPFEVVELHV
                     RPPAQGHGLGARQLRALLAVAEGDTTLLSTPEADEEKSRAWRLYRRFGFVDVLRHFHFP
                     GDERPFGVLGRDLPLPPPDES"
     gene            3149..3952
                     /locus_tag="MicB006_RS17385"
                     /old_locus_tag="MicB006_3499"
     CDS             3149..3952
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785286.1"
                     /locus_tag="MicB006_RS17385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3499"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_116507495.1"
                     /transl_table=11
                     /translation="MKARLPWALLAALILAQICYPLTGGSTRAGLTVATVVLGWLLSVG
                     HALLTRGARTAVALVAVVTGGGFAVEAIGVATGFPFGTYDYSGELGPKLAGVPLIIPLA
                     WTWMAWPAWLTAVRLVRSRLARIALSAVGLAAWDLFLDPQMVAEGYWTWRDATPALPGL
                     PGIPVSNYLGWLGFAVLLAVALRPLAGPSVDRVGGRDAPMFALYLWTYASSVLAHAVFL
                     RLPASALWGAAGMAVAAVPLAVTLWRARRDRAAEPEPAPRVDAPA"
     gene            3949..5076
                     /locus_tag="MicB006_RS17390"
                     /old_locus_tag="MicB006_3500"
     CDS             3949..5076
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018736171.1"
                     /locus_tag="MicB006_RS17390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3500"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_116511507.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.4e-12,
                     bitscore: 46.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAALALAAAVAALTGHTLVNAYAWLRRPTAGPAEVTEPVAVLLP
                     LRDEAERVNPCLRALLAQRGVPGLRIVVLDDGSTDGTADVVRAVAGDDPRLTLLTGVAT
                     PPGWLGKPHACWQLATRTAPEPTVLAFVDADVVLTPYAVAAAVTELRAADAALLSPYPR
                     IVVRTAADRLVQPLLQWLWLTFLPLRAMERSRRPSLAAAGGQFLVVDRAGYLRAGGHAA
                     VADKVLEDIELARAVKRAGGRIALADGSRLASCRMYDTWPQLRDGYTKSLWATFGHPTA
                     AAAVLALLVALYVAPPLLALGALLAGAPAVAAVAFLAYLAGVAGRVVSARATGGRAWPD
                     ALAHPVSVVVLGWLTVRSYHLRKRRRLTWRGRPVT"
     gene            5089..6576
                     /locus_tag="MicB006_RS17395"
                     /old_locus_tag="MicB006_3501"
     CDS             5089..6576
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014459.1"
                     /locus_tag="MicB006_RS17395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3501"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_116507497.1"
                     /sec_met_domain="DAO (E-value: 4.9e-10, bitscore: 38.0,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARIVVIGAGVGGLAAAARLAVTGHEVTVLERAGTVGGKLGRYAH
                     HTPEGVWHFDTGPSLFTLPQVFHDLFEATGAKLDEYLDVVPLDPIVRHVFPGGGPALDS
                     CADPDEFAARIGAAFGDRSAADWRGLRRRAGRVWAASHRDILRRTVDSPRDLAALAWRL
                     GDLAAIGPGRTLRGLGRRHLSDPRLRMLLDRYATYTGADPRRAPAALVAVPYAELAYGG
                     WYLRGGLGTLADALLSRCLDLGVVVRTDATVTRIDAAGGRVHGVRVAGSAAPVPADVVV
                     ANVDALTVYRNLLPDPRRLAALTDRSLAGFVLLLGVRGDSGLAHHNVFFPRDYDAEFDA
                     VFGDPGRGVRARPAPDPTVFVTAADDPAVRPDGHEAWFVLVNAPRHGTAASAVDWRRPG
                     LAEAYADRILDVLAERGADVRDRLVFREIRTPADLDAATGAPGGAIYGTAGGLLRPANR
                     GPVAGLWLVGGSSHPGGGLPMVTLSAEIVAEAVGPAW"
     gene            complement(6694..7383)
                     /locus_tag="MicB006_RS17400"
                     /old_locus_tag="MicB006_3502"
     CDS             complement(6694..7383)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287633.1"
                     /locus_tag="MicB006_RS17400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3502"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_073831031.1"
                     /transl_table=11
                     /translation="MVGTQLNWDQYATAWARLHGGFDPRTAAPVVRAWLRFAYHVGYVL
                     GRLRVGPTPVTVFGVLLCFCVPLFVERPGDGPFLGALFVLLAAVADSVDGAVAVATGRT
                     TRLGYVYDSVADRLGEVAWLIAFWLLGAPGALVAAAGGLSWLHEYVRARAVSAGMREIG
                     AVTVGERPTRVSVALVGLLVAGLTGLIDADLTAGTITMATTVWVLLAGFGLGQLLSAVR
                     RALVDAG"
     gene            complement(7428..8345)
                     /gene="metF"
                     /locus_tag="MicB006_RS17405"
                     /old_locus_tag="MicB006_3503"
     CDS             complement(7428..8345)
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785290.1"
                     /locus_tag="MicB006_RS17405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3503"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_116507499.1"
                     /transl_table=11
                     /translation="MALGLPSVLPNPQPAIGELIRDGRPTFSFEFFPPKTQAGEKLLWQ
                     AIRELESLRPSFVSITYGAGGSTRDTTVAVTERIATETTLLPMAHLTAVNHSVAELRHV
                     IGRLASVGVRNVLAVRGDPPGDPGGEWIAHPEGVRYAEDLVRLVRDSGDFSVGVAAFPY
                     KHPRSPDVASDTAYFVRKCRAGAEFAVTQMFFDADDYLRLRDRVAAAGCDTPILAGVMP
                     VTQIGTIERSVHLSGAPFPPALAERFERVADDPEAVRRLGVEQASEMCEKLLDEGVPGI
                     HFITLNRSTATREVWQRLRAAARV"
     gene            8501..9991
                     /locus_tag="MicB006_RS17410"
                     /old_locus_tag="MicB006_3504"
     CDS             8501..9991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287635.1"
                     /locus_tag="MicB006_RS17410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3504"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_225980398.1"
                     /transl_table=11
                     /translation="MTRRRRPGVRVAIRAVAPEVTMIPSSPPGPRLLGPLLAELRAARG
                     WSQQRLAAELCAASGVPTLTRHEVSRWERQLRLPGDFWSAWLATVLGVPGELLAGAAAS
                     SRRLGATPVAVDPAGSRARLALLTLAHRWAADPGGGTLAGPFTGPATPPVAGPATGDGY
                     GPPAADDSAGSGRRHPADGASLATLRRWDDLLGGGDLAGLGTRRLRRSVRGYRRAGPAG
                     RRRMLPSLAESAQLAGWLAADAGDLTGGLVAYRLALRAAMAAGEPPLAGHVLGSASHLL
                     ADAGDPAGALALARIGYAASRAAASPGLQALLLHRVALAAALGGRRRAAGQALAGADRA
                     GPPEPGREPPWLYWLDAAELAAMTGRTLVALGRPAAAVPLLTPVVTALGRPRRSAVYGG
                     WLARGHLGLGAEPEACAVAGEALLNAVRSGSPRAVGQLTEFRRGLTRRPPGPATRGYAR
                     LLAAARPYLPSRHRWRPSPPVSCEARRDGGTTGAGPNR"
     gene            10001..11083
                     /locus_tag="MicB006_RS17415"
                     /old_locus_tag="MicB006_3505"
     CDS             10001..11083
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215763.1"
                     /locus_tag="MicB006_RS17415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3505"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_116507501.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1e-48, bitscore:
                     164.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHAAPVSPVDRAGLRQRIDKALTEFLAGQRGWLTAVDDGLLPVA
                     EAIEAFVLGGGKRLRPAFGYWGYRGAGGVDSDQVVAALAALEFVQASALIHDDLMDRSD
                     TRRGEPAVHRRFAARHRAAGWGGDADAFGDSAAILLGDLCLVWSDELLHSSGLAPATVA
                     RARPIFDEMRTEVTVGQYLDVLTQATADTSLDRAAKVARYKSAKYTVERPLLLGAALAG
                     AQPEVHAAYSAYGLPLGEAFQLRDDVLGVFGDPELTGKPAGDDLREGKRTYLVAAALET
                     LDQAGREALLAGLGVPDLDAAGVDRLRELITTSGALERAEQHIAALTESALAALTAVDL
                     DTEARQALVDLAIAATRRPA"
     gene            complement(11235..11615)
                     /locus_tag="MicB006_RS17420"
                     /old_locus_tag="MicB006_3506"
     CDS             complement(11235..11615)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016816979.1"
                     /locus_tag="MicB006_RS17420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3506"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_116507503.1"
                     /transl_table=11
                     /translation="MTDSVPAETGADLAGPADPAGWLTLPDVAERLDLSISKVHQMIRD
                     RELLAVRRDGVRRVPADLVANHTVLKHLPGVLNLLDDAGYDDEEALRWLYREDPSLPGT
                     PAVALGGDLAREVKRRAQAVGF"
     gene            11758..13743
                     /gene="pknB"
                     /locus_tag="MicB006_RS17425"
                     /old_locus_tag="MicB006_3507"
     CDS             11758..13743
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018907613.1"
                     /locus_tag="MicB006_RS17425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3507"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_116507505.1"
                     /sec_met_domain="Pkinase (E-value: 3.9e-50, bitscore:
                     169.1, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 1.8e-05, bitscore: 23.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTQVADTLLGSLIEGRYRIRGRVARGGMATVYTATDERLERTVA
                     VKIIHPTQAPQARARMAGFVERFTDEAKTIARLTHPNVVAVYDQGIHAGLPYLVMEYVR
                     GRTLRDVLAERRRLNPDEALAITEQVLAALAAAHRAGLVHRDVKPENVLVAEVPAGGSR
                     DLVDSVVKVADFGLARAVEASAEDENGNQLMATVAYVAPELVTQGHADPRTDVYSAGIV
                     LFEMLTGRVPYDGDRPVEVAWQHVDRDVPPPSTLVPALPPAVDALVARATRRDPAARPA
                     DAAALLTEVQAAREELGNPHAHTAVLRQLSDDTAVLSQPTQVVAALQPIERPAWARLPE
                     GAATQRPHRRRAADPEGMGARFAALRTRIMGSPRGRLAVAAAVVVLGLVAAVGGWWFGV
                     GRYTVAPQMVSLTKAEAEAQAQRGGFTLRYADPRYDENVPKDTVLGQAPGSAARIVKGG
                     TITLTLSLGPERLPVPDVVGKDFALAQVELEGLNLVAAKGSSRYDDALPAGVVLATDPK
                     VGTVVKPGAKVTLILSKGRAPVSVPDLVGKSLTEARAILARLGLKPVENVKDSDKPKDE
                     ILGQSPADGTGVEKGAQVKLEISKGPPQVAVPRVIDMPCQQAKQTLESQGFPVNVQLNP
                     NGIVRIQNPAENTPVPPGTTVTVTCL"
     gene            13767..14609
                     /locus_tag="MicB006_RS17430"
                     /old_locus_tag="MicB006_3508"
     CDS             13767..14609
                     /EC_number="3.1.21.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0008833 - deoxyribonuclease IV
                     (phage-T4-induced) activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475762.1"
                     /locus_tag="MicB006_RS17430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3508"
                     /product="deoxyribonuclease IV"
                     /protein_id="WP_116511511.1"
                     /transl_table=11
                     /translation="MGSHTPTSGGLARAALPYAEAAESEVVQVYVSNSRGWALPAGDPA
                     QDALFRDGCGERGLPVFIHASLLVNLGSPTPATVTRSAETLAHALKRGRAIGAEGVVFH
                     AGSSVDAGHAEAALRQVRESLLPLLDEAAATGGPMLLVEPSAGGGRSLASRVEHLGPYL
                     DAVDRHPMLGVCFDTCHAWAAGHDLAAEGGMTATLDTLVATVGAGRLRLVHANDSKDLC
                     GSTRDRHENIGKGTIGEPAFAELMRHPATAGVPVLVETPTEKHVGHAADIATLKRLRP"
     gene            complement(14730..15749)
                     /locus_tag="MicB006_RS17435"
                     /old_locus_tag="MicB006_3509"
     CDS             complement(14730..15749)
                     /NRPS_PKS="Domain: Beta_elim_lyase (2-270). E-value:
                     8.6e-84. Score: 273.1. Matches aSDomain:
                     nrpspksdomains_MicB006_RS17435_Beta_elim_lyase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287640.1"
                     /locus_tag="MicB006_RS17435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3509"
                     /product="low specificity L-threonine aldolase"
                     /protein_id="WP_116511513.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7.4e-05,
                     bitscore: 20.7, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.7e-06, bitscore:
                     25.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDLRTDTVTRPTPGMREAMAAAEVGDDVYGEDPTVAALEAEVAA
                     LFGHEAALFAPSGSMANQLALQLHVPPGDELLCDADAHVVTYEVGAAAAYGGISSRTWP
                     AVGAELDPDVVAGMIRPDGYFAVPTRAIAVEQTHNRGGGGVIPLPTLRRLREVADEHGV
                     ALHCDGARIWHAHVADGVPLAEYGVLFDTLSVCLSKGLGAPVGSLVVGSAEKIARARVL
                     RKRMGGGMRQVGILAAAGRYALAHHVERLAEDHAKAARLAEAVAPHGVLASVARTNIVP
                     LDLTKHPLDAHALAAAARAAGLLISVLGPRTARLVTHLDVTDEQIDSAATILNTTLRA"
     aSDomain        complement(14940..15743)
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MicB006_RS17435_Beta_elim_lyase.
                     1"
                     /evalue="8.60E-84"
                     /label="MicB006_RS17435_Beta_elim_lyase.1"
                     /locus_tag="MicB006_RS17435"
                     /protein_end="270"
                     /protein_start="2"
                     /score="273.1"
                     /tool="antismash"
                     /translation="DLRTDTVTRPTPGMREAMAAAEVGDDVYGEDPTVAALEAEVAALF
                     GHEAALFAPSGSMANQLALQLHVPPGDELLCDADAHVVTYEVGAAAAYGGISSRTWPAV
                     GAELDPDVVAGMIRPDGYFAVPTRAIAVEQTHNRGGGGVIPLPTLRRLREVADEHGVAL
                     HCDGARIWHAHVADGVPLAEYGVLFDTLSVCLSKGLGAPVGSLVVGSAEKIARARVLRK
                     RMGGGMRQVGILAAAGRYALAHHVERLAEDHAKAARLAEAVAPHGV"
     gene            complement(15760..17166)
                     /locus_tag="MicB006_RS17440"
                     /old_locus_tag="MicB006_3510"
     CDS             complement(15760..17166)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009073 - aromatic amino acid family
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475760.1"
                     /locus_tag="MicB006_RS17440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3510"
                     /product="class II 3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="WP_116507507.1"
                     /transl_table=11
                     /translation="MRHEWHQLSHPAVGSPGLQTSRPTADSAEDAALGLDRWRELPRAQ
                     TPPWDDQAQVAEVCRVLDTVPSVVAPYEVDQLRQRLALVCEGKAFLLQGGDCAETFVDN
                     TESHLLANARTLLQMAIVLTYGASLPVVKVARVAGQYTKPRSLPTDARGLPAYRGDMIN
                     SLEATPEARVADPQRMIRAYANSAAAMNMLRAYLAGGLADLHAVHDWNKDFVRQSPAGE
                     RYDAIAREIDRALALIRACGMTDDEALRTVTLYCSHEALALEYDRALTRISDHKAYGLS
                     GHFLWIGERTRQIDGAHIDFISRIANPIGVKLGPTTTPDEAIELCEKLNPDNIPGRLTL
                     ISRMGNHRVRDALPPIVAKVTAAGAKVVWQCDPMHGNTHESSNGYKTRHFDRIVDEVLG
                     YFEVHRGLDTHPGGLHVELTGEDVTECLGGAQGIEDLDLPDRYETACDPRLNTQQSLEL
                     AFLVAEMLRG"
     gene            complement(17224..17754)
                     /locus_tag="MicB006_RS17445"
                     /old_locus_tag="MicB006_3511"
     CDS             complement(17224..17754)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287642.1"
                     /locus_tag="MicB006_RS17445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3511"
                     /product="hypothetical protein"
                     /protein_id="WP_116507509.1"
                     /transl_table=11
                     /translation="MDRSHRGRFAALALAFALTPALAACGSGPDGAATAPSGRAPAEEA
                     AAKSRERVQAYLDALTARDADAGRSQLCAPMHAAFDAAATGPNGDFADHFTVPDATITD
                     VRSGPNGQEVSASVTVAAGSRKATRALLFTVTRNGADWCISGEVPGERAVEPTADPAEP
                     APPAMAPSPVSSQ"
     gene            complement(17927..19561)
                     /locus_tag="MicB006_RS17450"
                     /old_locus_tag="MicB006_3513"
     CDS             complement(17927..19561)
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018807938.1"
                     /locus_tag="MicB006_RS17450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3513"
                     /product="glycosyl hydrolase family 18 protein"
                     /protein_id="WP_116507511.1"
                     /transl_table=11
                     /translation="MKRSLRRALWATGAVVALAVAAVPMTTASAAGSVTATFAKVQDWG
                     TGHEGRVTVTNGTSSTVNGWRIEFTLPSGTSISSSWDADITRSGDRYVAVNKSWASTLA
                     PGASFSWGYNGTGAYKAPVSCTINGGSCTGGGTPTTTAPTTAPPTTAPPTTAPPTTAPP
                     TTQPPTTPPPGGKKVVGYFAEWGVYARNYHVKNIHTSGSAAKLTHILYAFGNTTGGRCS
                     IGDSYADYEKAYTAADSVDGVADTWDQPLRGSFNQLRKLKKMYPNLKVLWSFGGWTWSG
                     GFTQAAQNPAAFADSCYSLVKDPRWADVFDGIDVDWEYPNACGLQCDSSGPNAFKNVVS
                     ALRSKFGSSFLVTAAITADGSNGGKIDATDYAGAATNLNWLMPMTYDYFGAFNAQGPTA
                     PHSPLYSYSGIPQQGFWSDAAIQKLKSKGVPSSKLLLGVGFYGRGWTGVTQAAPGGSAT
                     GAAPGTYEAGIEDYKVLKNSCPATGTVGGTAYAKCGSNWWSYDTPATIGGKMSYANSQG
                     LGGAFFWELSGDTSNGELIGAIKGGLG"
     misc_feature    complement(19575..19589)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.09"
                     /tool="antismash"
     misc_feature    complement(19589..19603)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.66"
                     /tool="antismash"
     gene            19705..20193
                     /locus_tag="MicB006_RS17455"
                     /old_locus_tag="MicB006_3514"
     CDS             19705..20193
                     /EC_number="1.11.1.-"
                     /GO_function="GO:0004602 - glutathione peroxidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0043295 - glutathione binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475757.1"
                     /locus_tag="MicB006_RS17455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3514"
                     /product="glutathione peroxidase"
                     /protein_id="WP_116507513.1"
                     /transl_table=11
                     /translation="MTVFDVQIDALTGGPADLGRYRGRALLVVNVASRCGLTPQYAGLQ
                     ELADTYAGRGLTVLGVPCNQFAGQEPGSAAEIEEFCQVNYGVTFPLTEKVDVNGPDRHP
                     LYAELVSTPDAEGHTGDVRWNFEKFLVAPDGTVAARFAPQVTPADPELRAAIEKVLPA"
     misc_feature    complement(20302..20313)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    complement(20816..20834)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.3"
                     /tool="antismash"
     misc_feature    20953..20971
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.94"
                     /tool="antismash"
     misc_feature    21014..21027
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     misc_feature    21065..21080
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 20.87"
                     /tool="antismash"
ORIGIN
        1 cgaggtggcg ccgctgcgcc ggggctggcc ggcgccgatc gcgacggtgc tgccgcggcg
       61 caggccacgg ttgggcagca gcccggtcag ctcggcccgg acgggaagca cccggtggcc
      121 gccggccggg tcgggcgcgc tcgccggccg gaccagctcg gccagggcgg cggagccgac
      181 caccatgcgg cccgccatcg gaccaacccc ccgtcgtgtt tcgccacggg tcccgcccgt
      241 ggatggtgct gtggatcgtg tgctgtggat cgtgtcggtg ctgcggcacg cggtgccgtt
      301 ggtgcggcgc ccggccaccc ggggtcccgc cggtggtggc cgggcgccac gaatcaggcg
      361 gctgccgctc cgggccgcga cggcggggag tcggaggcgc cgcgccgcag gggccggggc
      421 aggccgtcga gcgccggctg gtgcgccagg ccgagcgcgg tctccaccac tgtcacgaac
      481 tcctcggcgg cgcgcagcag gtcgtcggcc tcccgggcgg tgaccacgcg ggggatgccg
      541 gcctcggcgg cggcccgctt gctcgcgccg gccgcgaagt agacggccca ctcgtccagc
      601 tcgggggcga cggtggcgag cagcacccag acgctggtga tccggttccg ccgggtgggc
      661 gcgggacggg cccgggcggc gagcacggcg gcggcggcgc gcagcgccgc caggtgggcg
      721 gcggcgtacc ggaggccgtc gggacgggtg cgggcggcct cggccagccc gtcgcgggcc
      781 accgcgagca actgggcggg ggtgcggtgc ggcagcacgt gcgcgggcac cgtgggcgcc
      841 tgggccggac tggtcggcat gggtctctcc tccgcgtgtg gccggggcgg gcggtcgagc
      901 gacggaaacc gtcgcccggt cgcccggagc ggtcggtgcg gaggaagacg caccttgagg
      961 tggcgggccg gccgggtgtg gacgcttccc cacacccacc cccggccggc gtaccggcgg
     1021 gtccgtcgcc cgccgcccgg gggtcgtggg cggcgggcga cgacctgcct gacgggcccg
     1081 gactcgcgac tgtccgaacc cggtgcggcc cgcggtgccg cacctcccgg aaaccggtgc
     1141 cgcgaaacac cgtctccgga gcgttcgacg ggtgcgcgac cggctcgaac cggggccggt
     1201 cagccgggga gctgagccga tgccgttcgg actgggccga acttcgaacc ggaatcgaac
     1261 actcgttcta actaccctga cagtacacct cccccccgac gaaaacgcaa cgtgtgacgc
     1321 gccggggaca cacgggagga ccacggcccc cggcggggcc gtaccggggt gagggaagaa
     1381 tggggtcatg cagccacacc cgaacgtgca ggcggtgcag cgcgcgctcg acgaggcggg
     1441 cgcgcgggtc ggatcgggcg aggccagcct cgtccgactg ctgcccgacg cggtgcacac
     1501 cgccgccgcc gcggccgagg cgctcggcgt cgccgtcggc gccatcgcca actcgctgat
     1561 cttcgacgcg gacggcgcgc cgctgctggt gctcacctcc ggcgcgcacc gggtggacac
     1621 cgcggggctc gccgccacgc tgggcgtgac ccggctgcgc cgggccaccc cggaattcgt
     1681 caagcggcac accgggcagg tgatcggcgg cgtcgccccg gtcggccacc ccgcgccgct
     1741 gcgcaccgtc gtcgacaccg ccctgaccgg gtacgacgag gtgtgggccg caggcggcgt
     1801 accccgggcg gtgttcccca ccacgtacgc ggaactgctg cggatcaccg ccggcgctcc
     1861 ggccgaggtg gcgtgaaccc cgaactcgtc acgctgcacg tgtggcgtgt gccccggcgg
     1921 gccgtacccg gtgtgctggc ccggatggcc acccacccgg cgcggctgcg ccgcctgccc
     1981 ggcgtccgct tcgccaagct gctcggcacc gggaccggca ccggattcgg ccccggcgac
     2041 gccgacctga cccggtgggc cgcgctcgtg gtctgggact cccccgccga cgcggccggc
     2101 ttcgacgcct cccctgtcgc ccggtcctgg gcccggatcg cccgcgccgc ggtgcgggtg
     2161 gacctgcgcc cgctgaccag ccgcggccgg tggtccggcc gggagccgtt cggcgcgccg
     2221 tcgggcggac gggtcaccgg gccggtgctg gcgctgaccc gggcccggct gcggacccgc
     2281 cgggcggcca cgttctggcg ggcgatcccc ccggtcgccg ccgagctgca caccgcgccc
     2341 ggcctgctcg cccgcttcgg cgtcggcgag gcgccgctgg gctggcaggg cacggtgagc
     2401 gtgtggcgcg acccggcgga cctggtcgcg ttcgcgtacc gttcccccga gcaccgcgcc
     2461 gcgatcaccc gcacccccac cgagggctgg tacgcggagg aactgttcgc gcggttcgcg
     2521 gtgggcgacg tggccggcga ccgcacggtg ctcggctggg ccgccgagga cgacccggaa
     2581 acagcgagag ggtacgcatg aggctggtgc ggtggacgcc ggacgacctg gtccggcggc
     2641 tggacgacgt ggtggccgtc tacggcgagg cgatgggcta ccggcccgac ctgctggagg
     2701 cccgccgcgg ctacatcgcc acccacgtac gccggcccgg cttccgcgcc gtcgccagcc
     2761 tgaccagcga gggacacctg gccggcttcg ggtacggcta ccggggcgcc accgggcagt
     2821 ggtggcacga ccaggtgcac cgggcgctga acgcgcaggc ccggcagcgc tggctgaccc
     2881 acccgttcga ggtggtcgag ctgcacgtcc gcccgcccgc gcaggggcac ggcctgggcg
     2941 cccgccagtt gcgcgcgctg ctcgccgtgg ccgagggcga caccacgctg ctgtccaccc
     3001 cggaggccga cgaggagaag tcccgggcct ggcggctgta ccgccggttc ggtttcgtcg
     3061 acgtcctgcg gcacttccac ttccccggcg acgagcggcc gttcggcgtg ctcggccggg
     3121 acctgccgct gcccccgccg gacgagtcat gaaagcccgg ttgccctggg cgctgctggc
     3181 cgcgctgatc ctcgcccaga tctgctaccc gctcaccggc ggctccaccc gggccgggct
     3241 gacagtggcc accgtggtgc tcggctggct gctctcggtc ggccacgcgc tgctcacccg
     3301 cggcgcccgt accgccgtcg cgctggtcgc ggtcgtcacc ggcggcgggt tcgcggtgga
     3361 ggcgatcggc gtggccaccg gcttcccgtt cggcacctac gactactccg gcgagctggg
     3421 cccgaagctg gccggggtgc cgctgatcat cccgctggcc tggacctgga tggcctggcc
     3481 ggcgtggctc accgcggtcc ggctcgtccg ctcccgcctc gcccggatcg cgctctcggc
     3541 ggtggggctg gccgcctggg acctgttcct cgacccgcag atggtggccg agggctactg
     3601 gacctggcgc gacgccaccc cggctctgcc cgggctaccc ggcatcccgg tcagcaacta
     3661 tctgggctgg ctgggcttcg cggtgctgct ggcggtcgcg ctgcgcccgc tcgccgggcc
     3721 gtcggtggac cgggtcggcg gccgggacgc gccgatgttc gcgctctacc tctggacgta
     3781 cgcctccagc gtgctggcgc acgcggtgtt cctgcggctg ccggcgtcgg cgctgtgggg
     3841 cgcggccggg atggcggtgg cggcggtgcc gctggcggtg acgctgtggc gggcccgccg
     3901 ggaccgggcc gccgagccgg agccggcgcc gcgcgtcgac gccccggcat gatcgccgcc
     3961 ctcgcgctgg ccgcggcggt cgccgcgctc accgggcaca cgctcgtcaa cgcgtacgcc
     4021 tggctgcgcc gccccaccgc cggcccggcc gaggtgaccg agccggtggc ggtgctgctg
     4081 ccgctgcgcg acgaggccga gcgggtcaac ccgtgcctgc gcgcgctgct ggcccagcgc
     4141 ggcgtgccgg gcctgcggat cgtggtgctc gacgacggat cgaccgacgg caccgccgac
     4201 gtggtccgcg cggtggccgg cgacgatccc cgcctcacgc tgctcaccgg cgtcgccacg
     4261 ccgcccggct ggctgggcaa gccgcacgcc tgctggcagc tcgccacccg taccgccccg
     4321 gagccgacgg tgctggcctt cgtcgacgcg gacgtggtgc tcaccccgta cgcggtggcg
     4381 gcggcggtga ccgagttgcg cgcggccgat gcggcgctgc tgtcgccgta cccccggatc
     4441 gtggtgcgga cggcggccga ccggctggtg cagccgctgc tgcagtggtt gtggctgacg
     4501 ttcctgccgc tgcgcgcgat ggagcgctcg cggcggccct ccctcgcggc ggcgggcggg
     4561 cagttcctgg tcgtggaccg ggccggctac ctgcgggccg gcgggcacgc ggcggtggcc
     4621 gacaaagtgc tggaggacat cgagctggcc cgggcggtga aacgagcagg cgggcggatc
     4681 gcgctcgccg acgggtcccg gctggcgtcc tgccggatgt acgacacctg gccgcagctg
     4741 cgcgacggct acaccaagtc gctgtgggcg acgttcgggc accccaccgc cgcggcggcc
     4801 gtgctggcgc tgctggtcgc gctctacgtc gcgccgccgc tgctggccct cggcgcgttg
     4861 ctggccggcg cgccggcggt ggccgcggtg gcgttcctgg cctacctggc cggggtcgcc
     4921 gggcgggtgg tcagcgcccg cgccaccggc gggcgggcgt ggcccgacgc gctggcacac
     4981 cccgtgtcgg tcgtggtcct cggttggctg accgtccggt cgtaccatct gcggaagcga
     5041 cgccggctca cctggcgggg tcgcccggtc acctaggagg ggcacgccat ggcgcgcatc
     5101 gtggtcatcg gcgccggcgt gggcgggctc gccgccgccg cccggctcgc ggtcaccggg
     5161 cacgaggtca ccgtcctcga acgggccggc acggtcggag gcaagctcgg ccggtacgcc
     5221 caccacaccc cggagggggt gtggcacttc gacaccgggc cgagcctgtt caccctgccg
     5281 caggtcttcc acgacctgtt cgaggcgacc ggcgcgaagc tcgacgaata cctcgacgtg
     5341 gtcccgctgg acccgatcgt gcggcacgtc ttccccggcg gcgggcccgc gctcgactcc
     5401 tgcgccgacc cggacgagtt cgccgcccgg atcggcgccg cgttcggcga ccggtccgcc
     5461 gccgactggc gcgggctgcg gcggcgcgcc ggccgggtgt gggcggcctc gcaccgggac
     5521 atcctgcgcc gtaccgtcga ctcgccccgc gacctggccg cgctggcctg gcggctgggc
     5581 gacctggccg ccatcggccc cggccgtacg ctgcgcgggc tgggccgccg tcacctgtcc
     5641 gacccgcggc tgcggatgct gctggaccgg tacgccacgt acaccggcgc cgacccgcgc
     5701 cgcgccccgg ccgcgctcgt cgccgtcccc tacgccgaac tggcgtacgg cggctggtac
     5761 ctgcgcggcg ggctgggcac gctcgccgac gcgctgctgt cccgctgcct ggacctcggc
     5821 gtggtggtac gcaccgacgc cacggtcacc cggatcgacg ccgcgggcgg ccgggtgcac
     5881 ggggtacgcg tggccgggtc cgccgcgccg gtgccggccg acgtggtggt cgccaacgtg
     5941 gacgcgctca ccgtctaccg gaacctgctg cccgacccgc gccggctggc cgcgctcacc
     6001 gaccgcagcc tggccgggtt cgtgctgctg ctgggcgtac gcggcgactc cgggctggcc
     6061 caccacaacg tcttcttccc ccgcgactac gacgccgagt tcgacgccgt cttcggcgac
     6121 ccgggtcgcg gggtgcgggc ccgcccggcg ccggacccga ccgtgttcgt caccgcggcc
     6181 gacgacccgg cggtccgccc ggacggccac gaggcgtggt tcgtgctcgt caacgcgccc
     6241 cggcacggca ccgccgcgag cgctgtggac tggcggcggc ccggcctggc cgaggcgtac
     6301 gcggaccgga tcctcgacgt gctggccgaa cgcggcgccg acgtgcgcga ccggctggtg
     6361 ttccgggaga tccgcacccc ggccgacctg gacgcggcca ccggcgcgcc gggcggggcg
     6421 atctacggca ccgcgggcgg gctgctgcgc ccggccaacc ggggcccggt cgccgggctc
     6481 tggctggtcg gcggctccag ccaccccggc ggcggcctgc ccatggtgac gctgtccgcg
     6541 gagatcgtcg ccgaggcggt cggcccggcc tggtgaggtg taaggaaggg ccccttctta
     6601 acgcctccgg tagaggaagg gccccttctt aacgcgggca gcccgccgcg cggcggacag
     6661 cgcgggcagc gcgggcggcg cgggcacgga cggtcagccg gcgtcgacca gggcgcggcg
     6721 gacggcggag agcaactggc cgaggccgaa cccggcgagc agcacccaga ccgtggtggc
     6781 catggtgatg gtgccggcgg tcaggtcggc gtcgatcagg ccggtgagcc cggcgaccag
     6841 cagcccgacc agagcgacgc tgacccgggt cggccgctcg cccaccgtca ccgcgccgat
     6901 ctcccgcatc ccggccgaca ccgcgcgcgc ccgcacgtac tcgtgcagcc aggacaggcc
     6961 accggccgcc gcgaccagcg cgcccggcgc gccgagcagc cagaacgcga tcagccaggc
     7021 cacctcgccg agccggtcgg cgaccgagtc gtagacgtag cccaggcggg tggtgcggcc
     7081 ggtggcgacc gccaccgcgc cgtcgacgct gtcggccacc gcggccagca gcacgaacaa
     7141 cgcgcccagg aacggcccgt cgccgggccg ctccacgaac aggggtacgc agaagcagag
     7201 cagcaccccg aacacggtca ccggggtggg accgacgcgc agccggccca gcacgtagcc
     7261 cacgtggtag gcgaagcgca gccaggcacg caccaccggc gcggcggtac gcggatcgaa
     7321 gccgccgtgc agccgcgccc acgccgtcgc gtactggtcc cagttcagct gtgtgcccac
     7381 cacggatcaa ccgtagaagc acggcgcggg tgtcgtgtgg cgggtggtca cacccgtgcg
     7441 gccgcgcgca gtcgctgcca cacctcgcgg gtcgcggtgg accggttgag cgtgatgaag
     7501 tggatcccgg gcacgccctc gtcgaggagc ttctcgcaca tctcgctcgc ctgctcgacg
     7561 ccgaggcggc gcaccgcctc ggggtcgtcg gccacccgct cgaaccgctc ggcgagcgcc
     7621 ggcgggaacg gcgcgccgga cagatgcacc gagcgttcga tggtgccgat ctgggtcacc
     7681 ggcatcaccc cggccaggat cggcgtgtcg cagcccgcgg cggccacccg gtcgcgcagc
     7741 cgcaggtagt cgtcggcgtc gaagaacatc tgggtgacgg cgaactccgc gcccgcccgg
     7801 cacttgcgga cgaagtacgc ggtgtcgctg gccacgtccg gcgaccgcgg gtgcttgtac
     7861 gggaaggcgg caaccccgac gctgaagtca ccgctgtccc gtaccagccg gaccaggtcc
     7921 tcggcgtacc ggacgccttc ggggtgggcg atccactcgc cgcccgggtc gcccggcggg
     7981 tcgccccgca cggccagcac gttgcgcacc ccgaccgagg ccagccggcc gatcacgtgc
     8041 cgcagctcgg ccaccgagtg gttcacggcg gtgaggtgcg ccatcggcag cagcgtggtc
     8101 tcggtggcga tccgctcggt caccgccacc gtggtgtcgc gggtcgagcc gcccgcgccg
     8161 taggtgatcg agacgaacga ggggcgcagc gactcgagct cccggatggc ctgccagagc
     8221 agtttctccc cggcctgcgt cttcggcggg aagaactcga aggagaacgt cgggcggccg
     8281 tcacggatca gctccccgat ggccggctgg ggattgggga ggaccgaggg aagaccgagc
     8341 gccacggacc gactgtagcc gggagcgccc ggcttaccga gcgtcttccc agcccgcgaa
     8401 cactccgcgg cgcgacgtcg taccccgggg gtagaaagac cacagcgcgg tggggcggcc
     8461 gacggccgtc ccgggggccc gcgcgggggt cgccacgact gtgacgcgcc ggcgccggcc
     8521 gggcgtccgc gtcgccatcc gcgccgtcgc cccggaggtc accatgatcc cgtcctcgcc
     8581 gcccggcccg cgcctgctcg ggccgctcct ggccgagctg cgggccgccc gcggctggag
     8641 ccagcagcgg ctcgccgccg aactctgcgc cgcctccggc gtgcccaccc tgacccggca
     8701 cgaggtgtcc cgctgggagc gccagctccg gctccccggc gacttctggt ccgcctggct
     8761 ggcgacggtc ctgggcgtgc cgggcgagct gctcgccggg gccgccgcca gcagccgccg
     8821 gctcggcgcg acgcccgtcg ccgtcgaccc ggccgggtcc cgcgcccggc tggcgctgct
     8881 caccctggcg caccgctggg ccgccgaccc gggtggcggc acgctggccg gcccgttcac
     8941 cggcccggcg acgccgccgg tcgccggccc ggccaccggc gacgggtacg ggccgcccgc
     9001 cgccgacgac agcgccggct ccggtcggcg gcacccggcg gacggggcgt cgctggccac
     9061 gctgcggcgc tgggacgacc tgctcggcgg cggcgacctc gccgggctcg gcacgcgccg
     9121 gctgcgccgc tcggtccgcg gctaccggcg cgccgggccc gccggccggc ggcggatgct
     9181 gccgtcgctg gccgagtcgg cgcagctcgc cgggtggctg gccgccgacg ccggcgacct
     9241 caccggcggc ctggtcgcct accggctggc gctgcgggcc gcgatggccg ccggggagcc
     9301 gccgctggcc gggcacgtgc tcgggtcggc cagccacctg ctggccgacg ccggcgaccc
     9361 ggccggcgcg ctggccctgg cccggatcgg gtacgcggcc agccgcgccg ccgcctcccc
     9421 cgggctgcag gcgctgctgc tgcaccgggt cgcgctcgcc gccgcgctcg gcgggcggcg
     9481 tcgcgccgcc ggccaggcgc tggccggcgc cgaccgggcc gggcctccgg agcccggccg
     9541 ggagccgccc tggctgtact ggctggacgc ggccgagctg gccgcgatga ccgggcgcac
     9601 gctcgtcgcg ctgggtcgtc ccgccgcggc cgtgccgctg ctgacgcccg tggtgactgc
     9661 gctgggccgc ccgcgccgct cagcggtgta cggcggctgg ctggcccgcg ggcacctggg
     9721 gctcggcgcg gagcccgagg cgtgcgcggt ggccggcgag gcgctgctca acgcggtccg
     9781 ctccggctcg ccccgggccg tgggccagct caccgagttc cgccgcgggc tgacccgccg
     9841 tccgcccgga ccggcgaccc gggggtacgc gcggctgctc gcggcggccc gtccgtacct
     9901 gccgtcgcgg caccgatggc gaccgtcacc gccggtgagc tgcgaggcac gccgggacgg
     9961 tggcacgacg ggagcgggcc cgaaccgcta gcgtcgtggc gtgacccacg ctgctcctgt
    10021 ttcccccgtc gaccgtgccg gcctgcgtca gcggatcgac aaggcgctca ccgagttcct
    10081 ggccggccag cgcggctggc tgaccgccgt cgacgacggc ctgctgcccg tcgccgaggc
    10141 gatcgaggcg ttcgtgctgg gcggcggcaa gcggctgcgc ccggccttcg gctactgggg
    10201 ctaccggggt gccggcgggg tcgactccga ccaggtcgtc gccgccctgg ccgcgctgga
    10261 gttcgtgcag gccagcgcgc tgattcacga cgacctgatg gaccggtcgg acacccggcg
    10321 gggcgagcct gcggtgcacc gcaggttcgc cgcccggcac cgggcggccg gctggggcgg
    10381 cgacgcggac gccttcggcg actcggccgc gatcctgctg ggcgacctgt gcctggtctg
    10441 gtccgacgag ctgctgcact cctccggcct ggcgccggcg acggtggccc gggcccggcc
    10501 gatcttcgac gagatgcgca ccgaggtgac cgtcgggcag tacctggacg tgctgaccca
    10561 ggcgaccgcg gacacctcgc tcgaccgggc ggccaaggtg gcccggtaca agtcggcgaa
    10621 gtacacggtc gaacggccgc tgctgctggg cgccgcgctg gccggcgccc agcccgaggt
    10681 gcacgccgcc tactccgcgt acgggctgcc gctgggtgag gcgttccagc ttcgcgacga
    10741 cgtgctgggc gtgttcggcg acccggagct caccggcaag ccggccggtg acgacctgcg
    10801 cgagggcaag cggacgtacc tggtggcggc ggccctggag acgctcgacc aggccggccg
    10861 ggaggcgctg ctggccgggc tcggcgtacc ggacctggac gcggccgggg tggaccggct
    10921 gcgcgagctg atcaccacaa gcggcgcgct ggagcgcgcc gaacagcaca tcgccgcact
    10981 caccgagagc gcgctcgccg cgctcaccgc cgtcgacctg gacaccgagg cccgccaggc
    11041 gctggtggac ctggccatag ccgccacccg ccgccccgcc tgacggcccc tgcccacgcc
    11101 cactctcccc cgccacgccc gcctccgaag cggtcgatca tgaagttggc ggcacttttg
    11161 gagatcgact tcgccgccaa cttcatgatc aacgaggacg ggagggccgg ggcccgggtg
    11221 ggtgaagggt ggggctagaa gcccacggcc tgggctcggc gtttgacctc gcgggccagg
    11281 tcgccgccga gcgcgacggc cggggtgccg ggaagcgacg ggtcctcccg gtagagccag
    11341 cgcagcgcct cctcgtcgtc gtacccggcg tcgtcgagca ggttgagcac gccgggcagg
    11401 tgcttgagca cggtgtggtt ggccaccagg tcggccggga cgcggcggac gccgtcacgg
    11461 cgcaccgcga gcagttcgcg gtcgcggatc atctggtgca ccttgctgat cgacaggtcc
    11521 aggcgctcgg ccacgtcggg cagcgtcagc cagccggccg ggtcggccgg tccggccagg
    11581 tcggcgccgg tctcggcggg tacggaatcg gtcacccgac caccctgcca cgtgcccgcc
    11641 ggatccggtg cacggcaccc ccggaccggc ccgcgagcgc gccgggccac cggtgtccca
    11701 acccggcggt agcatcctgt tctacgttca cccttccgac acatagactg cctgccgatg
    11761 gacacacagg tcgccgacac gttgctgggc tcgctgatcg aggggcgcta ccgcattcgc
    11821 gggcgcgtcg cccgtggtgg catggcgacc gtgtacaccg ccaccgacga gcgcctggag
    11881 cgcaccgtgg cggtcaagat cattcacccg acccaggcgc cacaggcccg ggcccggatg
    11941 gccggcttcg tcgagcggtt caccgacgag gcgaagacga tcgcccggct cacccacccg
    12001 aacgtggtgg cggtctacga ccagggcatc cacgccggcc tgccgtacct ggtgatggag
    12061 tacgtgcgcg gccgcacgct gcgtgacgtg ctcgccgagc gccgccggct gaatccggac
    12121 gaggcgctcg cgatcaccga gcaggtgctc gccgcgctcg ccgccgcgca ccgggccggc
    12181 ctggtgcacc gggacgtcaa accggagaac gtcctggtcg ccgaggtgcc cgccggcggc
    12241 agccgcgacc tggtcgacag cgtggtcaag gtggccgact tcgggctggc ccgggccgtc
    12301 gaggcgagcg cggaggacga gaacggcaac cagctcatgg cgacagtggc gtacgtggcg
    12361 ccggagctgg tcacccaggg ccacgccgac ccgcgcaccg acgtctactc ggccggcatc
    12421 gtgctgttcg agatgctcac cggccgggtg ccctacgacg gcgaccgccc ggtggaggtc
    12481 gcctggcagc acgtcgaccg ggacgtgcct cccccgtcga cgctggttcc ggcgctgccg
    12541 ccggctgtcg acgcgctcgt cgcccgggcc acccggcggg acccggccgc ccgtccggcc
    12601 gacgccgcgg cgctgctgac cgaggtgcag gcggcccgcg aggagttggg caacccgcac
    12661 gcgcacaccg ccgtgctgcg ccagctcagc gacgacacgg cggtgctgag ccagccgacg
    12721 caggtggtgg ccgcgctgca gccgatcgag cgcccggcgt gggcccggct gcccgagggc
    12781 gccgccacgc agcgcccgca ccgccgccgc gccgccgacc cggaggggat gggcgcccgc
    12841 ttcgccgccc tgcgtacccg gatcatgggc tcgccgcgcg gccggctggc cgtcgccgcg
    12901 gcggtcgtgg tgctcggcct ggtcgccgcc gtcggcggct ggtggttcgg ggtgggccgc
    12961 tacacggtcg cgccgcagat ggtgagcctc acgaaggccg aggccgaggc gcaggcccag
    13021 cgcggtggtt tcacgctgcg ctacgccgac ccccggtacg acgagaacgt cccgaaggac
    13081 accgtgctcg gccaggcgcc gggctcggcc gcccggatcg tcaagggcgg cacgatcacg
    13141 ctgaccctgt cgctcggccc ggagcgcctg ccggtgccgg acgtggtggg taaggacttc
    13201 gcgctggccc aggtcgagct ggagggtctc aacctggtcg cggccaaggg cagctcccgc
    13261 tacgacgacg cgctgccggc gggtgtcgtg ctggcgaccg acccgaaggt ggggacggtg
    13321 gtcaagcccg gggccaaggt gacgctgatc ctcagcaagg gccgcgcccc ggtgagcgtg
    13381 cccgacctgg tcggcaagag cctcaccgag gcgcgcgcca tcctcgcgcg gctcgggctc
    13441 aagccggtgg agaacgtcaa ggactccgac aagccgaagg acgagatcct cggccagagt
    13501 ccggcggacg gcaccggcgt ggagaagggc gcccaggtca agctggagat cagcaagggc
    13561 ccgccgcagg tggccgtccc ccgggtgatc gacatgccct gccagcaggc caagcagacg
    13621 ctggagagcc agggcttccc ggtcaacgtg cagctcaacc cgaacggcat cgtccggatc
    13681 cagaacccgg ccgagaacac gccggtgccg ccgggcacga cggtcactgt gacgtgcctg
    13741 tgagcgccgc gaacgggtgc cggccggtgg ggtcgcacac ccccacctcc ggtggcctgg
    13801 cgcgggcggc cctgccgtac gcggaggcgg ccgagtccga ggtggtgcag gtctacgtct
    13861 cgaactcgcg tggctgggcg ctgccggccg gtgacccggc gcaggacgcg ctgttccgcg
    13921 acggctgcgg cgagcgtggc ctgcccgtgt tcatccacgc gtcgctgctg gtcaacctcg
    13981 gctcccccac cccggcgacg gtgacccggt cggcggagac gctcgcgcac gcgctgaagc
    14041 ggggccgggc gatcggcgcc gagggcgtgg tgttccacgc cggcagctcg gtggacgccg
    14101 ggcacgccga ggcggccctg cggcaggtcc gggagtcgct gctcccgctg ctcgacgagg
    14161 ccgcggccac cggcggaccg atgctgctgg tcgagccgag cgccggtggc ggccggtcac
    14221 tggcgtcccg ggtcgagcac ctcggcccct acctggacgc ggtcgaccgg cacccgatgc
    14281 tgggggtctg cttcgacacc tgtcacgcct gggcggccgg gcacgacctg gccgccgagg
    14341 gcggcatgac cgccacgctc gacacgctgg tcgccaccgt gggcgccggc cggctgcggc
    14401 tggtgcacgc gaacgactcg aaggacctgt gcggctccac ccgggaccgg cacgagaaca
    14461 tcggcaaggg caccatcggc gagccggcgt tcgccgagct gatgcgccat ccggcgacgg
    14521 ccggcgtgcc ggtgctggtg gagaccccca cggagaagca cgtcggccac gccgccgaca
    14581 tcgccaccct caaacgcctc cgcccctgac gggtcccccc tcaccccacc gccggccccg
    14641 gccgccccgg tgatcaagga gtttgtgtcc ggttccggcg cggaacagga cgccaactcc
    14701 ttgatcaccg ccggcgaagg cggggccggt caggcgcgca gggtggtgtt caggatggtg
    14761 gcggcgctgt cgatctgctc gtcggtgacg tccaggtggg tcaccagccg ggcggtacgc
    14821 gggccgagca ccgagatcag caggccggct gcccgcgcgg cggcggccag cgcgtgcgcg
    14881 tccagcgggt gcttggtcag gtccagcggc acgatgttgg tgcgcgccac cgacgcgagc
    14941 accccgtgcg gggcgaccgc ctcggccagc cgggccgcct tggcgtggtc ctcggcgagg
    15001 cgctcgacgt ggtgcgccag cgcgtaccgg ccggcggcgg cgaggatgcc cacctgccgc
    15061 atgccaccgc ccatccgctt gcgcaggacc cgcgcgcggg cgatcttctc cgcgctgccc
    15121 accaccagcg agccgacagg cgcgccgagg cccttggaga ggcagaccga cagcgtgtcg
    15181 aacagcacgc cgtactcggc cagcggcacc ccgtccgcga cgtgcgcgtg ccagatccgg
    15241 gcgccgtcgc agtgcagcgc caccccgtgc tcgtcggcga cctcgcgcag gcgacgcagc
    15301 gtcggcagcg ggatcacccc gccgccgccc cggttgtggg tctgctccac ggcgatcgcg
    15361 cgggtgggca ccgcgaagta gccgtcgggc cggatcatcc cggcgaccac gtcggggtcc
    15421 agctccgcgc ccaccgccgg ccacgtccgc gaggagatcc caccgtacgc ggcggcggcc
    15481 cccacctcgt acgtgaccac gtgcgcgtcg gcgtcgcaga gcaactcgtc gccgggcggc
    15541 acgtgcaact ggagcgcgag ctggttggcc atcgacccgc tcggggcgaa cagcgccgcc
    15601 tcgtggccga acaacgcggc cacctccgcc tccagggcgg cgaccgtggg gtcctcgccg
    15661 tagacgtcgt cgcccacctc ggcggcggcc atcgcctccc gcatccccgg cgtcggccgg
    15721 gtcacggtgt ccgtccgcag atcgatcaga ttcctcgcgt cagccacgga gcatctccgc
    15781 cacgaggaac gccaactcca gcgactgctg ggtgttgagc cgcgggtcgc aggcggtctc
    15841 gtaccggtcg ggcaggtcga ggtcctcgat gccctgggcg ccgccgaggc actcggtgac
    15901 gtcctcgccg gtcagctcga cgtgcaggcc gcccgggtgg gtgtccaggc cgcggtgcac
    15961 ctcgaagtag ccgagcacct cgtcgacgat ccggtcgaag tgccgggtct tgtagccgtt
    16021 cgaggactcg tgcgtgttgc cgtgcatcgg gtcgcactgc cagacgacct tcgcgccggc
    16081 ggcggtgacc ttcgccacga tcggcggcag cgcgtcgcgt acccggtggt tgcccatccg
    16141 gctgatcagc gtgagccggc cggggatgtt gtccgggttg agcttctcgc agagctcgat
    16201 cgcctcgtcc ggggtcgtgg tggggccgag cttgaccccg atcgggttgg cgatgcggga
    16261 gatgaagtcg atgtgcgcgc cgtcgatctg ccgggtccgc tcgccgatcc agaggaagtg
    16321 cccggacagg ccgtacgcct tgtggtcgga gatccgggtc agcgcccggt cgtactccag
    16381 cgccagcgcc tcgtgcgagc agtagagcgt gacggtgcgc agcgcctcgt cgtctgtcat
    16441 cccgcaggcc cggatgaggg ccagcgcccg gtcgatctcg cgggcgatcg cgtcgtagcg
    16501 ctccccggcc ggggactgcc ggacgaagtc cttgttccag tcgtgcacgg cgtgcaggtc
    16561 ggccaggccg ccggccaggt acgcgcggag catgttcatg gcggcggccg agttggcgta
    16621 cgcgcggatc atgcgctgcg ggtcggcgac ccgcgcctcc ggcgtggcct ccagcgagtt
    16681 gatcatgtcg ccgcggtagg cgggcagacc ccgggcgtcg gtcggcagcg accggggctt
    16741 ggtgtactgg ccggccaccc gggccacctt gaccaccggc agcgacgcgc cgtacgtgag
    16801 cacgatggcc atctggagca gcgtgcgggc gttggcgagc aggtggctct cggtgttgtc
    16861 gacgaacgtc tcggcgcagt caccgccctg gagcaggaac gccttgccct cgcagaccag
    16921 ggccagccgc tgccgcagct ggtcgacctc gtagggcgcg accaccgagg gaaccgtgtc
    16981 cagcacacgg cagacctcgg cgacctgggc ctggtcgtcc cacggcgggg tctgcgcacg
    17041 cggcagctcc cgccatcggt cgaggccgag ggctgcgtcc tcggcggagt cggcggtcgg
    17101 gcggctggtc tgcaggccag ggctgcccac ggcggggtga ctcagctgat gccactcatg
    17161 gcgcatggag gaaagcgtac ggcgaccgtc gcgatcactc gccgccgagg ggcatggttc
    17221 cggtcactgg gaggacaccg gggagggcgc catcgccggc ggcgccggct ccgccgggtc
    17281 ggcggtcggc tcgaccgcgc gctcgccggg cacctcgccg gagatgcacc agtccgcacc
    17341 gttacgggtc accgtgaaca gcagcgcccg ggtggccttg cgcgaaccgg cggccaccgt
    17401 gacggaggcg ctgacctcct gcccgttcgg gccggagcgg acgtcggtga tcgtcgcgtc
    17461 gggcaccgtg aagtggtcgg cgaagtcgcc gttcgggccg gtggcggcag cgtcgaaggc
    17521 ggcgtgcatg ggcgcgcaga gctggctgcg gccggcgtcg gcgtcgcggg cggtgagcgc
    17581 gtcgaggtac gcctgcacgc gctcccggct cttggccgcc gcctcctcgg cgggcgcccg
    17641 gccgctgggc gcggtggcgg cgccgtctgg gccggaaccg caggcggcca gcgccggcgt
    17701 gagcgcgaag gcgagcgcga gcgcggcgaa ccggcctcgg tggctgcgat ccatcggtcc
    17761 tcccgtcgcg tggactcgtc gagcggcgag tgtgtcacac ccggcccgcg cggccgggtg
    17821 actccccatc ctgacccgga tcggcgcgcg cggccagggc ggcacgcggg cggggagggg
    17881 ccggtacggc ccctccccgc cgggtgggtg gtgcgtcggc cctcggctag ccgagaccgc
    17941 ccttgatggc gccgatcagc tcaccgttgc tggtgtcacc ggagagctcc cagaagaacg
    18001 cgccaccgag gccctggctg ttggcgtagc tcatcttccc gccgatggtc gccggggtgt
    18061 cgtagctcca ccagttgctg ccgcacttgg cgtacgcggt gccgccgacc gtgccggtgg
    18121 ccgggcagct gttcttgagc accttgtagt cctcgatgcc ggcctcgtag gtgcccggcg
    18181 ccgcgccggt ggcgctgccg ccgggcgcgg cctgggtcac gccggtccag ccgcgtccgt
    18241 agaagccgac gccgagcagc agcttgctgg acggtacgcc cttggacttc agcttctgga
    18301 tcgccgcgtc cgaccagaag ccctgctgcg ggatgcccga gtacgagtag agcggcgagt
    18361 gcggcgcggt cggcccctgg gcgttgaagg cgccgaagta gtcgtacgtc atcggcatca
    18421 gccagttgag gttcgtcgcg gcgcccgcgt agtcggtggc gtcgatcttg ccgccgttgc
    18481 tgccgtcggc ggtgatcgcc gcggtgacca ggaagctgga gccgaacttg ctccgcagcg
    18541 ccgagaccac gttcttgaag gcgttcgggc cgctgctgtc gcactggagg ccgcaggcgt
    18601 tcgggtactc ccagtcgacg tcgatgccgt cgaagacgtc cgcccagcgc gggtccttga
    18661 ccagtgagta gcaggagtcg gcgaacgcgg ccgggttctg cgccgcctgg gtgaagccgc
    18721 cggaccaggt ccagccgccg aaggaccaga gcaccttcag gttcgggtac atcttcttca
    18781 gcttgcgcag ctggttgaag ctgccgcgca gcggctggtc ccaggtgtcg gccacgccgt
    18841 cgacgctgtc cgccgcggtg tacgccttct cgtagtcggc gtagctgtcc ccgatactgc
    18901 accggccgcc ggtggtgttg ccgaaggcgt acaggatgtg ggtgagcttc gcggccgagc
    18961 cgctggtgtg gatgttcttg acgtggtagt tgcgggcgta gacgccccac tcggcgaagt
    19021 agccgacgac cttcttgccg ccgggcggcg gcgtggtggg cggctgcgtg gtcggcgggg
    19081 cggtcgtcgg cggcgcggtg gtgggcggcg cggtcgtggg cggcgccgtg gtcggcgcgg
    19141 tggtcgtcgg cgtgccgccg ccggtgcagg agccgccgtt gatcgtgcag ctcaccggcg
    19201 ccttgtacgc gccggtgccg ttgtagcccc agctgaagct ggcgccgggg gcgagcgtcg
    19261 aggcccagct cttgttgacc gccacgtagc ggtcaccgct gcgggtgatg tcggcgtccc
    19321 aggagctgct gatcgaggtg ccggagggca gcgtgaactc gatgcgccag ccgttgacgg
    19381 tggagctggt gccgttggtg actgtcaccc ggccctcgtg gccggtcccc cagtcctgca
    19441 ccttggcgaa cgtggcggtg acgctgccgg cggccgacgc ggtggtcatg ggcaccgcgg
    19501 cgaccgcgag cgcgaccacg gcgccggtgg cccacagggc ccggcggagc gatctcttca
    19561 tacggcgtcc ctccaatagt taggaaagtt tccaaattga ttgctgagac gctactcacg
    19621 ccgtcaccac ttcgtcaaga tgtagatgcg tcgatttcac gggtggcgcg ggacggtccg
    19681 ggcgacggcc cgtagcctcg tcacatgacc gttttcgacg tccagatcga cgccctcacc
    19741 ggcggaccgg ccgatctcgg ccgctaccgt ggccgtgccc tgctcgtggt caatgtggcc
    19801 tcccgctgcg gcctcacccc gcagtacgcg ggccttcagg aactcgccga cacgtacgcc
    19861 gggcgcgggc tcacggtgct cggggtgccg tgcaaccagt tcgccggcca ggagccgggc
    19921 agcgccgccg agatcgagga gttctgccag gtcaactacg gcgtgacgtt cccgctgacg
    19981 gagaaggtgg acgtcaacgg gccggaccgg cacccgctct acgccgagct ggtgtccacg
    20041 ccggacgccg aggggcacac cggcgacgtg cgctggaact tcgagaagtt cctcgtcgct
    20101 ccggacggca cggtggccgc ccggttcgcc ccgcaggtca cgcccgcgga ccccgagctg
    20161 cgcgcggcga tcgagaaggt cctgccggcc tgacgaatgc gcgccgggac ggtgccgggt
    20221 cccggcgcgc attccgcgcg ttcacgaaca gacatcggca actccccgcg tacccaggga
    20281 aagaattcgc ccgcgcgaat cgaaaccgtt gtcgcaacaa caccgccgaa tcgtggcggc
    20341 gacccgactg tgtcctgttc ggtcgcaact ccgtccggcc gtacgagtgg accggcccgt
    20401 cgacccgggc gagcggtacc tacggccact ttccggagac cggcctgacc tcataacgtg
    20461 gctgaccccg gcacatcgtc atcgattggt ggtcacgtga cgagcacggt cgacggtccc
    20521 aggaacgcca cagaatcggc aactttcctc acgcatgatg cgccacgcga gcgacaaccg
    20581 ttaattgcgt ggcgcggcct accgcggtga acgattcgcc gacggacctg tcaccgaatt
    20641 ggtcgccgac ggccgccgga gcgtggcccc gaaagtcgag tacgacccgg agtacggccc
    20701 gggtgaacgt cctcaacggc caggggtccg cagccgccgg ccctggagca acggcgccgc
    20761 gcaacgacag cggcggcaag cgagaggaga agagcagtga cgtacgacgg taaccacggt
    20821 gtggtgatcc agtgctcgtc cagcggaccg gtggcggccg gaccaaaggc cactgcggat
    20881 caggtcgacc acatgggcga ggcgtcactg cgggagatct tggagcagtt gcgcgcgacc
    20941 cggcagcgga tcgaggagaa ccggtctcag ttggtcgaac cggagctggc gctggaggag
    21001 gtcgacgaca tcgtggacct gatccagcag gagcggccgg accgcaggcg ggtcatggtc
    21061 aaggtggacc ggctggtcac ccg
//
