LOCUS       NZ_CP030865            20951 bp    DNA     circular CON 14-AUG-2024
DEFINITION  Micromonospora sp. B006 chromosome, complete genome.
ACCESSION   NZ_CP030865
VERSION     NZ_CP030865.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sp. B006
  ORGANISM  Micromonospora sp. B006
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Complete Genome of Micromonospora sp. Strain B006 Reveals
            Biosynthetic Potential of a Lake Michigan Actinomycete
  JOURNAL   J Nat Prod 81 (9), 2057-2068 (2018)
   PUBMED   30110167
REFERENCE   2  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2018) Medicinal Chemistry and Pharmacognosy,
            University of Illinois at Chicago, 900 S Ashland Ave, Chicago, IL
            60607, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 77.6x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003408515.1-RS_2024_08_14
            Annotation Date                   :: 08/14/2024 03:31:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,342
            CDSs (total)                      :: 6,278
            Genes (coding)                    :: 6,199
            CDSs (with protein)               :: 6,199
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 20 of 79
            Pseudo Genes (incomplete)         :: 62 of 79
            Pseudo Genes (internal stop)      :: 6 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:07:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3844351
            Orig. end                         :: 3865302
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20951
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="16"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20951
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20951
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10951](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10951
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    8..23
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.02"
                     /tool="antismash"
     misc_feature    516..530
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.07"
                     /tool="antismash"
     gene            complement(<580..1230)
                     /locus_tag="MicB006_RS32365"
                     /pseudo=""
     CDS             complement(<580..1230)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037778.4"
                     /locus_tag="MicB006_RS32365"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRGSHARRAATEHSDVDVDVLVVADEGRAATGAGTRAAARRGGH
                     YAARRAYLTEFGGRLVHVSVAARDVRSWVRRLGQPADWAFGLPVTAPARLLWAVPEWRR
                     RIDLPVLCQPADEPRLEELIATLGKVAANRWAGDPVGVRLAAADLARLCPSVLRPANPS
                     VRVVSRRAALTAALDLPVAPPGYRDDMLLCLGLRHGDPAEVAAAAGRLVTGILP"
     gene            complement(1382..1771)
                     /locus_tag="MicB006_RS17020"
                     /old_locus_tag="MicB006_3426"
     CDS             complement(1382..1771)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785215.1"
                     /locus_tag="MicB006_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3426"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_116507405.1"
                     /transl_table=11
                     /translation="MDISTREMSLTVGEAAERVGLTTYTLRWYEQEGLVGRVGRDSSGR
                     RRYTESDVNWLFLLTRLRRTGMPVRDMRRYAELARHGDSTLGARRALFEAHRDRVLARM
                     AELEEDLKVLEYKIDAYRRAEEESS"
     gene            1882..2604
                     /locus_tag="MicB006_RS17025"
                     /old_locus_tag="MicB006_3427"
     CDS             1882..2604
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287559.1"
                     /locus_tag="MicB006_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3427"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_116507407.1"
                     /transl_table=11
                     /translation="MDDAVSVRELVVDRGGRRVLHGITCGVPRGTVTGLLGPSGSGKTT
                     LMRAVVGVQTVGSGAVDVLGRPAGSADLRRRVGYLTQAPSVYADLTVRENARYFAALQG
                     RGRAEADRAVTDVGLGKAAGQLVGTLSGGQRSRASLACALVGEPELVVLDEPTVGQDPV
                     LRADLWARFHAMAANGTTLLVSSHVMDEAARCDRLLLIREGRLVADDTPAAVRAATGTD
                     DLEEAFLRLIREAEGEAR"
     gene            2601..3356
                     /locus_tag="MicB006_RS17030"
                     /old_locus_tag="MicB006_3428"
     CDS             2601..3356
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="MicB006_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3428"
                     /product="ABC transporter permease"
                     /protein_id="WP_116507409.1"
                     /transl_table=11
                     /translation="MNGRILAATTGRILRQLRHDRRTVALLVVVPSVLLTLVYFMYVDQ
                     PTPPGAPSTFDRVALIMLGFFPFIIMFLVTSIAMLRERTTGTLERLLTTPLGKLDLLFG
                     YGIAFGLAGVLQSTVASVVAYRVFGLETAGSAWLVVLIAGVNAVLAVALGLFCSAFART
                     EFQAVQFMPVVVAPQLLLCGLFVPRDQMAGWLQAVSDALPLSYAVEALQEVGAHAEPTG
                     TMWRDVAVVAGAAVAALVLAAATLRRRSG"
     gene            3353..3949
                     /locus_tag="MicB006_RS17035"
                     /old_locus_tag="MicB006_3429"
     CDS             3353..3949
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287561.1"
                     /locus_tag="MicB006_RS17035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3429"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_116507411.1"
                     /transl_table=11
                     /translation="MNARRTGRRPGTPDTRDTILAAAREAFAERGFDAASIRAIAAAAG
                     VDPALVHHYFGGKEELFRAATAFPADPGRLLPAVLTGGPDGVGERMVRVFLEVWDSPAG
                     SAAVALLRSAVSNDWSARLLREFLVTQVLRRVLDHLDVDPAQRALRGGLVATQLAGLAM
                     MRYVLRLDAVATAEPATLVAAVGPTVQRYLTGDIA"
     gene            complement(3993..4724)
                     /locus_tag="MicB006_RS17040"
                     /old_locus_tag="MicB006_3430"
     CDS             complement(3993..4724)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785219.1"
                     /locus_tag="MicB006_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3430"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_116507413.1"
                     /transl_table=11
                     /translation="MRPSPAEIVRTLVAGRLPALVHLARHPGPHQVRHAVDPDGRVLLL
                     VPVVSDLAAALVPPPGDTDVATVLDVLDLPPTAGAPSLGRAWVSGWAARLDGDEARRAA
                     VDFAATEPTGDLLDVGRRFHLHRFEVAEARWERAGRVRRIDPEAFAEAEPDPLHPVEAA
                     LLADLADHHAEQVGDYLRRRLDLPGDRTPRVVRIDRYGLLVAHGRPGATRRARIAFARP
                     VADVAELSRLLHPMLCPRAAA"
     misc_feature    4739..4757
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 31.19"
                     /tool="antismash"
     gene            4788..5396
                     /gene="rpsD"
                     /locus_tag="MicB006_RS17045"
                     /old_locus_tag="MicB006_3431"
     CDS             4788..5396
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015561.1"
                     /locus_tag="MicB006_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3431"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_116507415.1"
                     /transl_table=11
                     /translation="MNHPRPKARISRALGIPLTRKCVRYFERRPYPPGVHGRSRRTTSD
                     YQVRLLEKQRLRHQYNVSEAQLRRLFDEAARAAGKTGETLVALLERRLDAVVLRAGLAR
                     SIYQARQLVGHGHVTVDGRKVDRPSYRLRPGQVVAVRERSRALPPFQLAAAGAHADAQP
                     RPYLSAQPAELRATLLREPARHEVPVVCDEQLVVEFYSR"
     gene            complement(5401..7182)
                     /locus_tag="MicB006_RS17050"
                     /old_locus_tag="MicB006_3432"
     CDS             complement(5401..7182)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475811.1"
                     /locus_tag="MicB006_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3432"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_116507417.1"
                     /transl_table=11
                     /translation="MSTTTGENTESTETTWQTLRRGLALSPELRTGLAGTIALALVYMV
                     GRVAVPVAVQRGIDHGIVGGLDLDVISVTVAITAGVLVVTTICGYLMMRRLFTVSETAL
                     AGVRTRAFRHVHDLSMLHQQSERRGSLVSRVTSDVDQITQFLQWGGVILIVNLGQLLVT
                     TAVMLAYSWQLTLVVLVAFAPAVLVIRQLQRRLAGAYGLVRQRTGTLLGAIGESVVGAP
                     VIRAYGIAGRTARRLDTAIDGQRVAQQRAIRISIMGSSVGELAAGLALAGVVVVGVSLG
                     VDGTLSIGQLTAFLFLVTLFIQPVQIATEVLNEAQNAIAGWRRVLDVLDVAPDVADPGD
                     QGRDLPAGPLDVRFAGVTFAYPGGPPVLHDVTLDIPAKSRVAVVGETGSGKTTFAKLLT
                     RLMDPSEGAVLLSGVDLRQVRFDSLRARVVMVPQDGFLFDATVGENVRFARPDLTDGQL
                     TAAFGELGLADWLDGLPSGLDTPVGERGEALSVGERQLVALARAYVADPDLLVLDEATS
                     AVDPATEVRLQRTLDAVTRGRTTLAIAHRLSTAQAADEVIVVDRGRIVQRGPHEELVRD
                     TDSVYALLYASWLEQTR"
     gene            complement(7179..9077)
                     /locus_tag="MicB006_RS17055"
                     /old_locus_tag="MicB006_3433"
     CDS             complement(7179..9077)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007462943.1"
                     /locus_tag="MicB006_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3433"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_225980396.1"
                     /transl_table=11
                     /translation="MRLTAGESVASKTSRDVLGRGLRVLGQAIREQPRIFAVAVSGSVL
                     FGLLVIASAYVVGGVVGNVVVPAVERGEVARGALALAATALFGISVLRVVGIFGRRLGA
                     GYMQYRLQAAYRRRVTRRYLELPLAWHHRNSTGTLLSNANSDVEAAWYPIAPMPFAVGT
                     LVMLVGAVASLFFTDWALALVGLAVFPALFALNVVYSRRMAPRQARAQRLRAEVSGIAH
                     ESFDGALVVKTMGREAQETARFAARAGDLRDALISVGRLRGVFDPMLETLPSLGTLAVL
                     VVGAIRLRQGAITVTELVSVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVRRVLDATG
                     EMPYGTRTLDPATRTPATLAFHDVHFAYEPAEAHLPGAQVLGEVTFTVPAGKTVALVGP
                     TGAGKSTIASLAVRLVDPGAGRVTLDGVDVRELTAASLAGTVALVAQVPFVFDDTVRAN
                     IALDRAGIGDDEVWAALRLAEADGFVAALPDGLDTMVGERGTSLSGGQRQRLTLARALA
                     GRPRLLVLDDATSAVDPRVEAAILAGLRAPADGGAPASILVVAYRRATIALADEVIYVE
                     QGRVVARGTHTELLATVPGYADLVTAYEQAEQEREQKQTYDEVTPMTSGLEIEVDR"
     gene            9246..9875
                     /locus_tag="MicB006_RS17060"
                     /old_locus_tag="MicB006_3434"
     CDS             9246..9875
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="MicB006_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3434"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_116507418.1"
                     /transl_table=11
                     /translation="MPRYARAEREALADLMLELGPDAPTVNEGWTTRDLAAHLLVRERR
                     PDAAGGILLPPLRGYGESVRRRIAAGPYADLIARVRRPPVWSPVSNPLTDELANGMEFF
                     IHHEDVRRARPGWQPRNLPAGQQAVLWKRVALLARMALRRFPAEVLVQAPGHGELRAGG
                     GGERLRLVGAPGELVLFLTGRQRVARVQVDGPAERVERLRNAELGL"
     misc_feature    complement(9928..9939)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.1"
                     /tool="antismash"
     gene            10001..10951
                     /locus_tag="MicB006_RS17065"
                     /old_locus_tag="MicB006_3435"
     CDS             10001..10951
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="MicB006_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3435"
                     /product="terpene synthase"
                     /protein_id="WP_073830976.1"
                     /sec_met_domain="T1TS (E-value: 2.3e-73, bitscore: 246.5,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDFALSALHEPPFPSRCHPATDEVAAQSVAWVRGFGLIKDRAGL
                     LRLTGAHASELAGRACPDASPAGLRLLTDLINWLFVVDDACDDDGLGAAPTVLAPTLAA
                     LLAVLDRHGDPDAPAPTDAGPMGLALHDLCRRARGRGRPAHLMRLVSQLREYLLALLWE
                     AANRERRRVPGVAEYVQMRRHTGGVRPSFTVTDLARPSLPRPDQRANPALTALDALATD
                     LVCWCNDMFSYGKERGVAPEAHNLVTTIAGETGKDESAALNAAANCFNTALASYAERDA
                     ALSAGADEGMRAFLDTRRDWIRATYDWSRAASRYA"
     misc_feature    complement(11046..11061)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            11091..12917
                     /locus_tag="MicB006_RS17070"
                     /old_locus_tag="MicB006_3436"
     CDS             11091..12917
                     /NRPS_PKS="Domain: AMP-binding (14-471). E-value: 7.4e-88.
                     Score: 286.8. Matches aSDomain:
                     nrpspksdomains_MicB006_RS17070_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="MicB006_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3436"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_116507420.1"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-85, bitscore:
                     285.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDVPYRSVPDMFLKRVADSPDRQAFAHPAPDDSGPVWLTWEQV
                     GQRAKAIAAGLHGLGVGLENPVAILANTRLDWVLADFGIMCAGGATTTVYPTTEPDEAV
                     FIIADSGSKVLFAENPAQAAKIAGADLPALTHVVLFDGSPDPAAAVPQLTLAELEERGA
                     AALSAEPDLIDMLVAGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLR
                     TDDLQYLWLPLSHSFGKTLLCGATHVGLPTYVDGRVDKLVDLLGVVRPTLMCGAPRVFE
                     KVYNKAVTTAQGAGGAKAKIFAWGVAVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSK
                     LQARLGGRMRVLVSGAAPLSQEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGS
                     VGRAMGDLECRIDSDGEVLMRGKPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDSDGY
                     LRITDRKKDLVKTSGGKYVAPSHIEGMFKAVCPYTSQAVVIGQARNYCTMLVTLDPDAI
                     KAWAAGTPLEGSDYTTIVTSPQAREMVEGYVAELNAKLNRWETIKKVSILPRDLTIEDG
                     EVTPSLKIKRRSVETNFASEIDKMYEGTLAEL"
     aSDomain        11133..12503
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MicB006_RS17070_AMP-binding.1"
                     /evalue="7.40E-88"
                     /label="MicB006_RS17070_AMP-binding.1"
                     /locus_tag="MicB006_RS17070"
                     /protein_end="471"
                     /protein_start="14"
                     /score="286.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LKRVADSPDRQAFAHPAPDDSGPVWLTWEQVGQRAKAIAAGLHGL
                     GVGLENPVAILANTRLDWVLADFGIMCAGGATTTVYPTTEPDEAVFIIADSGSKVLFAE
                     NPAQAAKIAGADLPALTHVVLFDGSPDPAAAVPQLTLAELEERGAAALSAEPDLIDMLV
                     AGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLRTDDLQYLWLPLSHS
                     FGKTLLCGATHVGLPTYVDGRVDKLVDLLGVVRPTLMCGAPRVFEKVYNKAVTTAQGAG
                     GAKAKIFAWGVAVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSKLQARLGGRMRVLVS
                     GAAPLSQEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGSVGRAMGDLECRIDS
                     DGEVLMRGKPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDSDGYLRITDRKKDLVKT"
     CDS_motif       11646..11705
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MicB006_RS17070_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="MicB006_RS17070"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     CDS_motif       12333..12407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MicB006_RS17070_0002"
                     /evalue="3.00E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="MicB006_RS17070"
                     /protein_end="439"
                     /protein_start="414"
                     /score="22.8"
                     /tool="antismash"
                     /translation="GEVLMRGKPVMRGYHNLPEETAAAF"
     gene            complement(12981..14249)
                     /locus_tag="MicB006_RS17075"
                     /old_locus_tag="MicB006_3437"
     CDS             complement(12981..14249)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475806.1"
                     /locus_tag="MicB006_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3437"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_116511497.1"
                     /transl_table=11
                     /translation="MRAGAPGSRTTRLELFYDLVFVFAFLSVTTLTASELTPVNLYRFL
                     LVLALLWWSWTGFARLGNAFRADQGVLPLVGFITMAATFLLVLSEPDAFENNPGGLPGP
                     LVFAGCYFVIRMAQLAVFGCLDRSDPVRRRRLLMRAAFPTTATVLLVVAGTVPARLPQE
                     RFAIPLQLSLWTLALLVEYVGGVTLARQWWMVLSAGHWAERHALIVLVALGESIIALGF
                     GKHGLPLTGPVAVSALLGIVVVAALWWAYFDTFSFALEQALHKARDEEARIRITRDVYT
                     FLHLAMVAGIVLFALGLKDLLVEAADTSTPDWGPPLGNFWGVVMYGGVALYLLGLARCW
                     WLALREVRRPLLLTVVALAVVGPIAFQIAELMALAVLAIITGAGVAWETGRENGYRRRI
                     RQLALEEQIAAEAEQSHWRQQHL"
     gene            complement(14358..15809)
                     /locus_tag="MicB006_RS17080"
                     /old_locus_tag="MicB006_3438"
     CDS             complement(14358..15809)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (111-461). E-value:
                     1.1e-29. Score: 95.6. Matches aSDomain:
                     nrpspksdomains_MicB006_RS17080_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="MicB006_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3438"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_073830979.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-27, bitscore:
                     95.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGVQLARLLGQWHALPGRRRSPDYAALAAAVRGLLADGRL
                     PLGVRLPAERELAEALRISRTTVTAAYRELRESGHLASRRGAGSWTMLPGGHRVASTGL
                     WTPLDDRDMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELREAVARGY
                     TERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALSARRARIAT
                     HGLSDEGWDAELLLGSIRQTRPKLAYVIPEFHNPTGHLMAADLRERLVGAAHAAGTDLV
                     VDESFVDLPLDDTPLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAPQVQRLAA
                     ARVGVDMASPVLDQLVAVHLLAEAPAIVAARRAQLAAQRDALVAALAEQLPDWRVTVPR
                     GGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLAAEELVEAV
                     GRLAAVRYDLDRAGRPQWREAGVIA"
     aSDomain        complement(14427..15476)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MicB006_RS17080_Aminotran_1_2.1"
                     /evalue="1.10E-29"
                     /label="MicB006_RS17080_Aminotran_1_2.1"
                     /locus_tag="MicB006_RS17080"
                     /protein_end="461"
                     /protein_start="111"
                     /score="95.6"
                     /tool="antismash"
                     /translation="DMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELR
                     EAVARGYTERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALSA
                     RRARIATHGLSDEGWDAELLLGSIRQTRPKLAYVIPEFHNPTGHLMAADLRERLVGAAH
                     AAGTDLVVDESFVDLPLDDTPLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAP
                     QVQRLAAARVGVDMASPVLDQLVAVHLLAEAPAIVAARRAQLAAQRDALVAALAEQLPD
                     WRVTVPRGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLAA
                     EELVEAVGRL"
     gene            15869..16504
                     /locus_tag="MicB006_RS17085"
                     /old_locus_tag="MicB006_3439"
     CDS             15869..16504
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785228.1"
                     /locus_tag="MicB006_RS17085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3439"
                     /product="YitT family protein"
                     /protein_id="WP_116507422.1"
                     /transl_table=11
                     /translation="MAPLGNLGHRPARRLTQLYAGLVLYGLSMALMIRSELGLDPWDVF
                     HQGLSRQTGLSFGTVTIAVGALVLLLWIPLRQRPGLGTVSNVVVIGLVVDATLAVLPPG
                     DGMPARAAMLVAGIVANGAATGLYLGAGLGPGPRDGLMTGFVARHPRFSVRLVRTSIEI
                     TVLALGWLLGGPVGLGTVAYALTIGPLAQFFIPVFALPARPPRGAYAT"
     gene            16621..17082
                     /locus_tag="MicB006_RS17090"
                     /old_locus_tag="MicB006_3440"
     CDS             16621..17082
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018804515.1"
                     /locus_tag="MicB006_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3440"
                     /product="hypothetical protein"
                     /protein_id="WP_116507423.1"
                     /transl_table=11
                     /translation="MGENGWRWSDAWIFVALVIASGAGRHRRSASTRRPEGVRLADVLS
                     TADHLNQAIPERHEVEGAVRRLVGAGLVSVSDGWFRVTPDGEQLWRTRPSAGLGTTVDT
                     VQGVLTRRHPPGESEWQLDEDDHAAAVQEYVVRSIPMPRRSPEGRSGRQ"
     gene            complement(17092..17859)
                     /gene="hisF"
                     /locus_tag="MicB006_RS17095"
                     /old_locus_tag="MicB006_3441"
     CDS             complement(17092..17859)
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - L-histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="MicB006_RS17095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3441"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_116507425.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASSSDRGTMLDVVRRTAESVFIPLTVGGGVRQVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGRQVLVLSLDVRRAPDGTTPSGFEVTTHGGRRGTGLDAVEWA
                     ARGAELGAGEILLNSMDADGTKAGFDLPLIQAVREVVDVPVIASGGAGEVAHFPPAVGA
                     GADAVLAASVFRLGELTVGQVKDALRGAGHPVR"
     gene            complement(17905..18897)
                     /locus_tag="MicB006_RS17100"
                     /old_locus_tag="MicB006_3442"
     CDS             complement(17905..18897)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016628 - oxidoreductase activity, acting
                     on the CH-CH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (19-328). E-value: 4.4e-20.
                     Score: 64.0. Matches aSDomain:
                     nrpspksdomains_MicB006_RS17100_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785231.1"
                     /locus_tag="MicB006_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3442"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_116507427.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.5e-22, bitscore:
                     76.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNREIHLASRPQGWPTAENFRLVTTEVPTPGPGQVVVRNRFMSVD
                     PYMRGRMNDVKSYVPPFALDAPLDGGAIGEVVAGEAGGVKPGDVVLHGLGWREYALVDA
                     RGARKVDPDLAPVTAYLGVLGMTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGSMVGQI
                     AKLRGAGRVIGSAGSRAKVERLTALGFDAAFDYHDGPVSKQLRAAAPDGVDVYFDNVGG
                     DHLEAAIGAMNLHGRAAICGMIAQYNATEPPAAPRNLALVIGKRLTLRGFLVSDHGHLR
                     EQFVQEVAGWLREGRLSYDETVIDGIEQAPEAFLGLLRGENLGKMLVRL"
     aSDomain        complement(17914..18840)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MicB006_RS17100_PKS_ER.1"
                     /evalue="4.40E-20"
                     /label="MicB006_RS17100_PKS_ER.1"
                     /locus_tag="MicB006_RS17100"
                     /protein_end="328"
                     /protein_start="19"
                     /score="64.0"
                     /tool="antismash"
                     /translation="FRLVTTEVPTPGPGQVVVRNRFMSVDPYMRGRMNDVKSYVPPFAL
                     DAPLDGGAIGEVVAGEAGGVKPGDVVLHGLGWREYALVDARGARKVDPDLAPVTAYLGV
                     LGMTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGSMVGQIAKLRGAGRVIGSAGSRAKV
                     ERLTALGFDAAFDYHDGPVSKQLRAAAPDGVDVYFDNVGGDHLEAAIGAMNLHGRAAIC
                     GMIAQYNATEPPAAPRNLALVIGKRLTLRGFLVSDHGHLREQFVQEVAGWLREGRLSYD
                     ETVIDGIEQAPEAFLGLLRGENLGKMLV"
     CDS_motif       complement(18424..18468)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_MicB006_RS17100_0001"
                     /evalue="8.90E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="MicB006_RS17100"
                     /protein_end="158"
                     /protein_start="143"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GETVFVSGAAGAVGS"
     gene            complement(18894..19319)
                     /locus_tag="MicB006_RS17105"
                     /old_locus_tag="MicB006_3443"
     CDS             complement(18894..19319)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785232.1"
                     /locus_tag="MicB006_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3443"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_073830984.1"
                     /transl_table=11
                     /translation="MQVLYTASARATGDGRDGHVRTSDGTVELDLAVPKEMGGAGGAAN
                     PEQLFAAGYAACFHSALRVVARKAKADVSGSVVEAEVGIGPNGSGGFGLAVTLVVDLPA
                     VERSAAEQLVDAAHQVCPYSNATRGNVEVTRTVREAR"
     gene            complement(19321..19767)
                     /locus_tag="MicB006_RS17110"
                     /old_locus_tag="MicB006_3444"
     CDS             complement(19321..19767)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789360.1"
                     /locus_tag="MicB006_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3444"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_116507429.1"
                     /transl_table=11
                     /translation="MTDDLVLRRQVCFALYAASRALTDVYRPILDEHGLTYPQYLVLLV
                     LWERYDDAPTVSELGAALRLDSGTLSPLLKRLEAAGLVVRTRSAADERRVEVGLTDQGR
                     ALRERMCDVPRQVATATGLTETELVFLHGILTRVTETIHRQKEQ"
     misc_feature    complement(19777..19794)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.03"
                     /tool="antismash"
     misc_feature    19781..19797
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 21.87"
                     /tool="antismash"
     gene            complement(19846..20262)
                     /locus_tag="MicB006_RS17115"
                     /old_locus_tag="MicB006_3445"
     CDS             complement(19846..20262)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785234.1"
                     /locus_tag="MicB006_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3445"
                     /product="RidA family protein"
                     /protein_id="WP_116507431.1"
                     /transl_table=11
                     /translation="MTAEPPVDAGVVTRLGSGGPWEALYGYSRVVRAGSLAITAGCTST
                     VDGRVAHAGDAAAQTAQAIRIGLDALAEVGAGPGDVVRTRMYVTDRIYADEVGRAHNAV
                     FGPVRPVATMVVVAGLIDPDMLVEVELEAYLPAG"
     misc_feature    20398..20413
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.05"
                     /tool="antismash"
     misc_feature    20777..20791
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 cggggagctg accggcaggt cggtgaagaa gcacgtgcgc tgcccggtgt ggcaggccgc
       61 gccgacctgc tccacgctga ccagcagcgc gtcgccgtcg cagtccagcg ccaccgagcg
      121 cacgtactgg tggttgccgg aggtggcgcc cttgacccag tactcgccgc ggctgcgcga
      181 ccagtaggtg gcccggccgg tggtgagcgt gcggtgcagc gcctcgtcgt ccatccaggc
      241 gaccatcagc acctcgcccg agtcgtgggc gcggaccacg gcggcgacca ggccgtccgg
      301 ggtgcggcgg agcctggccg cgatggccgg gtcgagccgg gacgggcggg ccgggccggg
      361 agcggtggcg ccgttcagcg gcgcgtcagg ggcgggcacg gttgaccatt ctcccgcacg
      421 cggccccggc accgccgacg tgtcccggga ggcgggcgtc accgtcgccg gcgcccggcc
      481 gagctgccgc aggtagcggt ccacccggcc gtcggtgagc gcctcggcca ggtcggtccc
      541 ggcgacccgg gcgatctccg ccgcgtacgg gcgcaccagc gggaggatgc cggtgaccag
      601 ccgtccggcg gcggcggcga cctcggccgg gtcgccgtgg cgcagcccga ggcagagcag
      661 catgtcgtcg cggtagccgg gcggggcgac cggcaggtcc agcgcggcgg tcagggccgc
      721 ccggcgggac accacgcgca ccgacgggtt ggccggccgc agcaccgagg ggcagagccg
      781 ggccaggtcg gccgcggcga gccggacccc gaccgggtca ccggcccagc ggttggcggc
      841 gaccttgccc agcgtggcga tcagctcctc cagacgcggc tcgtcggcgg gctggcagag
      901 caccggcagg tcgatccggc gccgccattc cggcaccgcc cacagcagcc gggccggcgc
      961 ggtcaccggc agcccgaacg cccagtcggc gggctggccg agccggcgca cccaggaccg
     1021 gacgtcgcgg gccgccaccg agacgtgcac gaggcgaccg ccgaactcgg tcaggtacgc
     1081 ccgccgggcg gcgtagtggc cgccgcgccg ggcagcggcg cgggttcccg cgccggtggc
     1141 ggcacgccct tcgtcggcga ccacgagcac gtccacgtcc acgtcgctgt gctcggtggc
     1201 ggcccgccgg gcgtggctgc ctcgcagcat gatcccgacg accggacggt cggcggtctg
     1261 ccgcagacgg gcggcccagt cgtcgaggaa tccggtgtcg ggcaactgcg ctggacccac
     1321 ggcgtcatgg tgccgagatc cgatcttccg gtgccggact ccctgtccgc caccgaggcg
     1381 ttcagctcga ctcctcctct gcccgccggt acgcgtcgat cttgtactcg agaaccttca
     1441 ggtcctcctc cagctcggcc atccgggcca gcacccggtc ccggtgcgcc tcgaacagcg
     1501 cccggcgcgc gccgagcgtg ctgtcgccgt gccgggccag ctcggcgtag cggcgcatgt
     1561 cgcgcaccgg catcccggtg cgccgcagcc gggtgagcag gaacagccag ttgacgtcgg
     1621 actcggtgta gcgccggcgg cccgaggagt cccgtccgac gcggcccacc aggccctcct
     1681 gctcgtacca gcgcagcgtg taggtggtca ggccgacccg ttccgccgcc tcacccacgg
     1741 tgaggctcat ctcccgcgtg ctgatgtcca cgccctccag gcttccagtt cgagcgcact
     1801 cgaagtcaag tccctcgttg cctcgtcgaa ggaattcatc tagcgttgag ttcaacgagt
     1861 gatgaattga cggaggcgag catggacgac gcggtgtcgg tccgcgagct ggtggtcgac
     1921 cggggcgggc ggcgggtgtt gcacggcatc acctgcggag tgccccgggg caccgtgacc
     1981 gggctgctcg ggcccagcgg cagcggcaag accacgctga tgcgcgcggt ggtcggcgta
     2041 cagacggtcg gctccggcgc ggtcgacgtg ctcggccgcc cggccggctc ggccgacctg
     2101 cgccgccggg tgggctacct gacccaggcg ccgagcgtct acgccgacct gaccgtgcgg
     2161 gagaacgccc gctacttcgc ggcgctccag ggccggggcc gcgccgaggc cgaccgcgcg
     2221 gtcaccgacg tcggcctggg caaggcggcc ggccagctcg tcggcacgct ctccggcggc
     2281 cagcgcagcc gcgcctcgct cgcctgcgcc ctggtcggcg aaccggagct ggtggtgctg
     2341 gacgaaccca ctgtcggcca ggacccggtg ctgcgcgccg acctgtgggc ccggttccac
     2401 gccatggccg cgaacggcac cacgctgctg gtctccagcc atgtgatgga cgaggcggcc
     2461 cgctgcgacc ggctgctgct gatccgcgag ggccggctgg tcgccgacga cacccccgcg
     2521 gcggtccgcg ccgccaccgg gaccgacgac ctggaggagg cgttcctgcg cctgatccgc
     2581 gaggccgagg gagaggcacg atgaacggac ggatcctggc cgccaccacc ggacgcatcc
     2641 tgcgccagct ccggcacgac cggcggaccg tggcgctgct cgtcgtggtg ccgtcggtgc
     2701 tgctcacgct cgtctacttc atgtacgtcg accagcccac cccgcccggc gcgcccagca
     2761 cgttcgaccg ggtggccctg atcatgctcg gcttcttccc gttcatcatc atgttcctcg
     2821 tgaccagcat cgccatgctc cgcgagcgca ccacgggcac gctggagcgc ctgctcacca
     2881 cgccgctggg caagctcgac ctgctgttcg ggtacggcat cgcgttcggc ctggccgggg
     2941 tgctccagtc cactgtcgcc tcggtcgtcg cgtaccgggt gttcgggctg gagaccgccg
     3001 gcagcgcgtg gctggtcgtg ctgatcgcgg gggtgaacgc ggtgctggcg gtggcgctcg
     3061 ggctgttctg ctccgcgttc gcccgcaccg agttccaggc ggtccagttc atgccggtgg
     3121 tggtggcccc gcaactgctg ctctgcggcc tgttcgtgcc gcgcgaccag atggccggct
     3181 ggctccaggc ggtcagcgac gcgctgccgc tgtcgtacgc ggtcgaggcg ctgcaggagg
     3241 tcggcgcgca cgccgagccg accgggacga tgtggcggga cgtggcggtc gtggccgggg
     3301 cggcggtggc ggcgctggtg ctggccgccg cgacgctgcg tcggcgcagc gggtgaacgc
     3361 gcggcgcacc ggacggcggc ccggcacccc ggacacccgg gacaccatcc tcgccgccgc
     3421 gcgggaggcg ttcgccgagc ggggcttcga cgccgcgtcg atccgggcca tcgccgccgc
     3481 ggccggtgtg gacccggcgc tcgtgcacca ctacttcggc ggcaaggagg agctgttccg
     3541 ggccgcgacg gcgttcccgg ccgacccggg acggctgctg ccggcggtgc tcaccggcgg
     3601 cccggacggg gtcggcgagc ggatggtccg ggtcttcctg gaggtctggg actccccggc
     3661 cgggagcgcc gcggtcgcgc tgctgcgctc ggcggtcagc aacgactgga gcgcccggct
     3721 gctgcgcgag ttcctggtca cgcaggtgct gcgccgggtg ctcgaccatc tcgacgtcga
     3781 cccggcgcag cgcgcgctgc gcggcgggct ggtcgccacc cagctcgccg ggctggccat
     3841 gatgcggtac gtgctccgcc tcgacgcggt cgccaccgcc gagccggcga cgctggtggc
     3901 cgccgtcgga ccgacggtcc agcggtacct caccggcgac atcgcctgag ccgcctccgc
     3961 gccccgcggc gtcgacggcg gtccggcccg cctcaggccg cggcccgggg gcacagcatc
     4021 gggtgcagca ggcgggacag ctccgccacg tcggccacgg gccgcgcgaa ggcgatccgg
     4081 gcccgccggg tcgcgccggg ccgcccgtgc gcgaccagca ggccgtacct gtcgatccgg
     4141 accacccgcg gcgtccggtc gccgggcagg tccagccgcc gccgcaggta gtcaccgacc
     4201 tgctcggcgt ggtggtcggc caggtcggcc agcagggcgg cctcgaccgg gtgcagcggg
     4261 tccggctcgg cctcggcgaa cgcctccggg tcgatgcgcc gcacccgccc ggcgcgctcc
     4321 cagcgcgcct cggccacctc gaagcggtgc aggtggaacc ggcggcccac gtcgagcagg
     4381 tcgccggtgg gttcggtggc ggcgaagtcg acagcggccc ggcgcgcctc gtccccgtcg
     4441 aggcgggccg cccagccgga cacccaggcc cggccgagcg agggcgcgcc ggcggtcggc
     4501 ggcagatcca gcacgtcgag cacggtggcc acgtcggtgt cgcccggcgg cggcacgagc
     4561 gcggcggcca ggtcgctgac caccggtacg agcagcagca cccgcccgtc cgggtcgacg
     4621 gcgtgccgga cctgatgcgg gccggggtgc cgggccaggt ggacgagggc gggcaaccgg
     4681 cccgcgacca gggtacgcac gatctccgcc gggctgggcc gcatgatccg cctccaaggt
     4741 aggttaggct tacctaagaa gcaggctaga cgatcggaga cgtccccgtg aaccaccccc
     4801 ggcccaaagc ccggatctcg cgcgccctcg gcatcccgct gacccgcaag tgcgtgcggt
     4861 acttcgagcg gcgcccctat cccccgggcg tgcacggccg gtcccgccgc accacctccg
     4921 actaccaggt gcggctgctg gagaagcagc ggctgcgcca ccagtacaac gtcagcgagg
     4981 cccagctgcg ccggctcttc gacgaggccg cccgggccgc cggcaagacc ggcgaaacgc
     5041 tcgtcgcgct gctggaacga cgtctcgacg cggtggtcct gcgcgccggg ctggcccgca
     5101 gcatctacca ggcccgccag ctcgtcgggc acggccacgt cacggtcgac ggccgcaagg
     5161 tcgacaggcc ctcgtaccgg ctgcggcccg gccaggtggt cgcggtacgc gagcgcagcc
     5221 gcgcgctgcc gccgttccag ctcgccgccg ccggcgcgca cgccgacgcg cagccccggc
     5281 cgtacctgtc ggcgcagccg gccgagctgc gcgccacgct gctgcgcgaa ccggcccggc
     5341 acgaggtgcc ggtggtctgc gacgagcagc tggtggtgga gttctactcc cgctgaccgg
     5401 ttaccgggtc tgctccagcc aggaggcgta cagcagcgcg tagaccgagt cggtgtcgcg
     5461 gaccagctcc tcgtgcgggc cgcgctgcac gatccggccc cggtccacca cgatcacctc
     5521 gtcggccgcc tgcgcggtgg agagccggtg cgcgatggcg agcgtggtcc gcccccgggt
     5581 caccgcgtcg agcgtgcgtt gcaggcgtac ctcggtggcc gggtcgacag cgctcgtcgc
     5641 ctcgtcgagc accagcaggt ccgggtcggc gacgtacgcg cgggccagcg ccacgagctg
     5701 ccgctcgccg acgctgagcg cctccccgcg ctccccgacc ggcgtgtcca gcccggacgg
     5761 cagcccgtcc agccagtcgg ccaggcccag ctcgccgaag gcggcggtga gctgcccgtc
     5821 ggtcaggtcg gggcgggcga agcggacgtt ctccccgacc gtggcgtcga acaggaagcc
     5881 gtcctgcggc accatcacca cccgggcgcg cagcgagtcg aaccgcacct gccgcaggtc
     5941 gaccccggag agcagcaccg cgccctcgct cgggtccatc aggcgggtga gcagcttggc
     6001 gaacgtggtc ttgccgctgc cggtctcgcc caccaccgcc acccggctct tcgccgggat
     6061 gtcgagcgtg acgtcgtgca gcaccggcgg gccgcccggg taggcgaacg tcacaccggc
     6121 gaaccggacg tcgagcgggc cggccggcag gtcccgcccc tggtcgcccg gatcggccac
     6181 gtccggcgcg acgtccagca cgtccagcac ccggcgccag ccggcgatcg cgttctgcgc
     6241 ctcgttgagc acctcggtgg cgatctgcac cggctggatg aagagcgtga ccaggaacag
     6301 gaacgcggtg agctggccga tcgacagcgt gccgtcgacg ccgaggctca ccccgaccac
     6361 caccacgccg gccagcgcca gcccggccgc cagctccccc accgagctgc ccatgatgct
     6421 gatccggatc gcccgctgct gggccacccg ctggccgtcg atcgccgtgt ccagccgccg
     6481 cgcggtccgc ccggcgatgc cgtacgcccg gatcaccggc gcgcccacca cgctctcgcc
     6541 gatcgcgccg agcagcgtgc cggtgcgctg ccgcaccagc ccgtacgccc cggcgaggcg
     6601 gcgctgcaac tgccggatca ccagcaccgc cggcgcgaac gcgacgagca ccacgagcgt
     6661 caactgccag gagtacgcga gcatcaccgc tgtggtcacc agcagctggc ccaggttgac
     6721 gatgaggatc acgccgcccc actggaggaa ctgggtgatc tggtcgacgt cgctggtgac
     6781 ccgggagacc agcgagccgc gccgctcgga ctgctggtgc agcatcgaca ggtcgtgcac
     6841 gtgccggaac gcccgcgtgc gcacaccggc cagggcggtc tcgctcaccg tgaacagccg
     6901 gcgcatcatc aggtagccac agatggtggt gacgaccagc accccggcgg tgatcgccac
     6961 ggtgaccgag atgacgtcca ggtcgagccc gccgacgatg ccgtggtcga tgccgcgctg
     7021 caccgccacc ggcacggcga cccggccgac catgtagaca agcgccagcg cgatcgtgcc
     7081 cgcgaggccg gtgcgcagct ccggcgagag cgccagcccg cgccgcagcg tctgccaggt
     7141 ggtctcggtg ctctcggtgt tctcccccgt ggtcgtactc accggtcaac ctcgatctcc
     7201 aggccggagg tcatcggcgt gacctcgtcg tacgtctgct tctgctcgcg ttcctgctcg
     7261 gcctgctcgt acgcggtgac caggtcggcg tagccgggca cggtggccag cagctcggtg
     7321 tgggtgccgc gggcgaccac ccggccctgc tccacgtaga tcacctcgtc ggcgagcgcg
     7381 atggtggccc ggcggtacgc gaccaccagg atcgacgccg gggcgccgcc gtcggcgggg
     7441 gcgcgcagcc cggccaggat ggccgcctcg acgcgcgggt cgacagcgct cgtggcgtcg
     7501 tcgagcacca gcagccgggg gcggccggcg agcgcccggg ccagcgtcag ccgctggcgc
     7561 tgcccgccgg acagcgacgt cccccgctcg ccgaccatgg tgtccagccc gtccggcagc
     7621 gcggccacga agccgtccgc ctcggccagc cgcagcgccg cccacacctc gtcgtcgccg
     7681 atgccggccc ggtccagcgc gatgttggcc cggaccgtgt cgtcgaagac gaacggcacc
     7741 tgcgccacca gcgccacggt gccggcgagc gaggcggcgg tcagctcccg cacgtccacg
     7801 ccgtccagtg tgacccgccc ggcgcccggg tcgaccagcc gcactgcgag cgaggcgatc
     7861 gtggacttgc ccgcgccggt gggccccacc agggcgaccg tcttcccggc gggcactgtg
     7921 aacgtcacct cgccgagcac ctgggcgccg ggcaggtgcg cctcggccgg ctcgtacgcg
     7981 aagtgcacgt cgtggaacgc gagcgtggcc ggcgtgcggg tggccgggtc gagcgtcctc
     8041 gtgccgtacg gcatctcgcc ggtcgcgtcg agcacgcggc ggacccggtc ccacccggcg
     8101 acgctgcgcg gcagctcggc aagcacccag ccgatggcgc gcaccgggaa cgccagcacg
     8161 gtgaacagga aggcgacgct gaccagctcg gtcacggtga tcgcgccctg ccgcagccgg
     8221 atcgcgccga ccaccagcac ggcgagcgtg ccgaggctgg gcagcgtctc cagcatcggg
     8281 tcgaagacgc cgcgcagccg gccgaccgag atcagcgcgt cccgcaggtc accggcgcgg
     8341 gccgcgaagc gggcggtctc ctgcgcctcg cggcccatcg tcttgaccac cagcgcgccg
     8401 tcgaagctct cgtgcgcgat gccgctgacc tcggcgcgca gccgctgcgc ccgggcctgg
     8461 cggggcgcca tccggcggga gtagaccacg ttgagcgcga acagcgcggg aaagaccgcc
     8521 aagccgacca gggccagcgc ccagtcggtg aagaacagcg aggccaccgc gccgaccagc
     8581 atcaccagcg tgccgaccgc gaacggcatg ggcgcgatcg ggtaccaggc ggcctcgacg
     8641 tcggagttgg cgttcgacag cagcgtgccg gtggagttgc ggtggtgcca ggccagcggc
     8701 agctccaggt agcggcgggt gacccggcgg cggtaggcgg cctggagccg gtactgcatg
     8761 tagccggcgc cgagccgccg gccgaagatg ccgacgaccc gcagcacgct gatgccgaac
     8821 agcgccgtcg cggccagcgc cagggccccg cgggccacct cgccgcgctc gaccgccggc
     8881 acgacgacat tgccgaccac cccgccgacc acgtacgcgc tggcgatcac caggaggccg
     8941 aagagcacgc tgccgctgac cgccaccgcg aagatccgcg gctgttcccg gatggcctgg
     9001 ccgagcaccc gtagccctct gccgaggacg tcccgacttg tcttgctcgc cacgctctcc
     9061 cccgccgtaa gccgcatctt tctcccccat ccttaccgct cgtcgccgac tccgccgacc
     9121 cggccgggat atgtccgccg tcacgttccg ctcgacctgg gcggacagcg gccgctgacg
     9181 ctcccggccc atcctcgcgc cgggcgtggc gcgccgaact gcccggacgg gcctacgatc
     9241 gggccatgcc gcggtacgcc cgagcggagc gcgaggcgct cgccgacctg atgctggaac
     9301 tgggaccgga cgcgccgacc gtcaacgagg ggtggaccac ccgggacctg gccgcgcacc
     9361 tgctggtgcg ggaacgccgg ccggacgcgg ccggcggcat cctgctgccg ccgctgcgcg
     9421 gctacggcga gtcggtgcgc cggcggatcg ccgccgggcc gtacgccgac ctgatcgccc
     9481 gggtccgccg tcccccggtg tggagcccgg tgagcaaccc gctcaccgac gagctggcga
     9541 acgggatgga gttcttcatc caccacgagg acgtccgccg ggcccgtccc ggctggcagc
     9601 cgcggaacct tcccgccggg cagcaggcgg tgctctggaa gcgggtcgcc ctgctggccc
     9661 ggatggcgct gcggcgcttc ccggccgagg tgctggtgca ggcgccgggg cacggcgagc
     9721 tgcgggccgg tggcggcggc gagcggctgc ggctcgtcgg cgcgccgggg gaactcgtgc
     9781 tgttcctcac cggacggcag cgggtggccc gggtccaggt ggacggcccg gccgaacgcg
     9841 tcgagcgcct gcgtaacgcc gaactgggcc tgtgagcgac gtttccgccc gttcacaagc
     9901 gatcgtagaa tgtggacacc cggcatcgat aacgttcgcc ggctgccgta cgctcctgcg
     9961 aaccgtcccg accccgcggg gcggcggaca ggggacgacg atgcgggact tcgcgctctc
    10021 ggcgctgcac gagccgccct ttccctcccg atgtcacccg gccaccgacg aggtggccgc
    10081 gcagagcgtc gcctgggtgc gcggattcgg cctgatcaag gaccgcgccg gcctgctccg
    10141 gctgaccggg gcccacgcct cggagctggc cggacgggcc tgccccgatg cctccccggc
    10201 cggcctgcgg ttgctcaccg acctgatcaa ctggctgttc gtggtagacg acgcctgcga
    10261 cgacgacggg ctgggcgccg caccgacagt gctcgcgccc accctggcgg cgctgctggc
    10321 ggtgctcgac cggcacggtg acccggacgc gcccgcgccc accgacgccg gcccgatggg
    10381 cctggcgttg cacgacctgt gccggcgggc ccgcggccgg gggcggccgg cgcacctgat
    10441 gcgactggtg agccagttgc gggagtacct gctggcgctg ctctgggagg ccgcgaaccg
    10501 ggagcgccgg cgcgtgcccg gggtcgccga gtacgtgcag atgcgccgcc acaccggagg
    10561 cgtacgcccc agcttcacgg tgaccgacct ggcccgcccg tccctgcccc ggcccgacca
    10621 gcgggcgaac ccggcgctca ccgcgctgga cgccctcgcc accgacctgg tctgctggtg
    10681 caacgacatg ttctcctacg gcaaggagcg gggcgtcgcc ccggaggcgc acaacctggt
    10741 gaccaccatc gcgggcgaga ccgggaagga cgagtcggcg gcgttgaacg cggcggcgaa
    10801 ctgcttcaac acggcgctcg cgtcgtacgc ggagcgggac gcggcgttga gcgccggggc
    10861 ggacgagggg atgcgggcgt tcctggacac ccgccgggac tggatccggg ccacctacga
    10921 ctggtcccgc gccgccagcc ggtacgcctg atccggctcc agcagtcggg accggtgggg
    10981 actcggccga tcagggctag ccgctggccg ggtgcaggca atacccttcg gtaaccgcag
    11041 atcgacgtga cccccgtcac gtccctccac ccctgaaggc ggctacagcg atggctctcg
    11101 atgtaccgta ccgttccgtt cccgatatgt tcctcaagcg cgtggcggat tcccccgacc
    11161 ggcaggcgtt cgcccacccc gcacccgacg actcgggccc ggtctggctg acgtgggagc
    11221 aggtcgggca gcgcgcgaag gcgatcgccg ccgggttgca cgggctcggt gtcggcctgg
    11281 agaacccggt ggcgatcctg gccaacaccc ggctggactg ggtgctggcc gacttcggca
    11341 tcatgtgcgc cggcggggcc accaccaccg tctacccgac caccgagccc gacgaagcgg
    11401 tcttcatcat cgccgactcc ggctcgaagg tgctgttcgc ggagaacccg gcccaggcgg
    11461 cgaagatcgc cggggcggac ctgcccgcgc tgacccacgt ggtgctcttc gacggctcgc
    11521 ccgatccggc cgccgccgtc ccgcagctca ccctggccga gctggaggag cgcggcgccg
    11581 ccgcgctgag cgccgagccc gacctgatcg acatgctcgt cgccggcatc ggcccggacc
    11641 acctggcgac gctcatctac acctcgggca ccaccggccg cccgaagggc gtggagctgc
    11701 tgcacggcgg ctggtgctgg gagggcgtgg cgcaggccga gctcggcctg ctgcgcaccg
    11761 acgacctgca gtacctgtgg ctgccgctgt cgcactcgtt cggcaagacg ctgctctgcg
    11821 gcgccaccca cgtcggcctg cccacgtacg tcgacggccg ggtggacaag ctggtcgacc
    11881 tgctcggcgt ggtccggccg acgctgatgt gcggcgcgcc ccgggtcttc gagaaggtct
    11941 acaacaaggc ggtcaccacc gcgcagggcg cgggcggcgc gaaggccaag atcttcgcgt
    12001 ggggcgtcgc ggtcggcaag gagaaggtgg cgctggagca ggccggcaag ccggtgccgg
    12061 ccgggctgcg gatgaagtac gcgctggccg agaagctggt gttcagcaag ctgcaggccc
    12121 ggctcggcgg ccggatgcgg gtgctggtct ccggcgcggc gccgctgagc caggagatcg
    12181 cgaccttctt cgccgccgcc aacctgccca tctccgaggg ctacggcctg accgagacca
    12241 gcgccggcgc gttcgtcaac ccgcccgacg ggctgaagat cggcagcgtg ggccgggcca
    12301 tgggtgacct ggagtgccgg atcgacagcg acggcgaggt cctcatgcgg ggcaagccgg
    12361 tcatgcgggg ttaccacaac ctgccggagg agaccgccgc cgcgttcacc gaggacggct
    12421 tcttccgcac cggtgacatc ggcacgctcg actccgacgg ctacctgcgc atcaccgacc
    12481 ggaagaagga cctggtcaag acgtccggcg gcaagtacgt cgcgccgtcg cacatcgagg
    12541 gcatgttcaa ggcggtctgc ccctacacct cgcaggcggt ggtgatcggc caggcgcgca
    12601 actactgcac catgctcgtc acgctggacc cggacgcgat caaggcctgg gccgccggca
    12661 ccccgctgga gggcagcgac tacaccacga tcgtcacctc gccgcaggcg cgggagatgg
    12721 tcgagggcta cgtggccgag ctcaacgcca agctcaaccg ctgggagacg atcaagaagg
    12781 tgtcgatcct cccccgtgac ctcaccatcg aggacggcga ggtcacgccg tcgctgaaga
    12841 tcaagcgtcg cagcgtggag acgaacttcg cctccgagat cgacaagatg tacgagggca
    12901 cgctcgccga gctgtagccc gcaccgccag tcggtagcgc cggccgtgcc ccaccgtccc
    12961 ggggcacggc cgcgtgccgt tcagaggtgc tgctgccgcc aatggctctg ctcggcctcg
    13021 gcggcgatct gctcctccag cgcgagctgg cgtatccggc gccgataacc gttctcgcgg
    13081 cccgtctccc aggcgacacc ggcgccggtg atgatcgcga gcacggcgag cgccatcaac
    13141 tccgcgattt ggaacgcgat cgggccgacc acggccagcg ccaccaccgt gagcagcagc
    13201 ggccggcgca cctcgcgcag cgcgagccac cagcaccggg cgaggccgag caggtacagc
    13261 gcgaccccgc cgtacatgac cacaccccag aagttgccga gtggcggccc ccagtcgggc
    13321 gtgctcgtgt cggcggcctc gaccagcagg tccttgaggc cgagcgcgaa gaggacgatc
    13381 ccggcgacca tcgccaagtg caggaacgtg tacacgtccc gggttatccg gatccgggct
    13441 tcttcgtccc gggccttgtg cagggcttgt tccagcgcga aggagaacgt gtcgaagtac
    13501 gcccaccaca gagccgccac gaccacgatg ccgagcaacg ccgacaccgc caccgggccg
    13561 gtcagcggca gcccgtgctt gccgaacccg agcgcgatga tcgactcgcc gagcgcgacg
    13621 agcacgatca gcgcgtgccg ttccgcccag tgcccggccg agagcaccat ccaccactgg
    13681 cgggccagcg tcacgccgcc cacgtactcg acgagcaacg ccagcgtcca gagcgacagt
    13741 tgcagcggga tcgcgaaccg ctcctgcggc aggcgcgccg gcacggtgcc ggcgacaacg
    13801 agcagcacgg tggcggtggt cgggaacgcg gcccgcatca ggagccggcg gcgccggacc
    13861 ggatcggatc ggtccaaaca gccgaagacc gcgagctggg ccatccggat cacgaagtag
    13921 cagccggcga agaccagcgg gccgggcagc ccgccgggat tgttctcgaa cgcgtcgggc
    13981 tcgctgagca ccagcaggaa cgtcgctgcc atggtgatga agccgaccag cggcagcaca
    14041 ccctggtcgg cgcggaacgc gttgccgagg cgggcgaagc cggtccacga ccaccacagc
    14101 aacgccagca ccagcaggaa gcggtagagg ttgaccggcg tgagctccga cgcggtgagc
    14161 gtggtgacgc tcaggaacgc gaagacgaag accaggtcgt agaagagctc cagccgggtg
    14221 gtgcgggagc ccggtgcgcc ggcccgtatg atccacgacc gccgcggctc gctcccgttc
    14281 cccaccccgg cagtctgcgg gcaccgcctg ccccgtagcc gccgttcggc gcaaccacca
    14341 ccggatcggg cgggcggtca ggcgatgacg ccggcctcgc gccactgcgg gcggccggcc
    14401 cggtccaggt cgtagcgcac cgcggcgagc cggcccaccg cctccaccag ctcctcggcg
    14461 gccagtgtga agggcaggcg caggaagcgc tcgagcgtcc cgtccaggcc gaaccggggt
    14521 ccgggcgcca gccgtacgcc gacctcctcg gcggcccggg ccagcgcgct ggagatcggg
    14581 ccgtccagct cggcccagag cgtcacgccg ccgcgcggca ccgtgacccg ccagtcgggc
    14641 agctgctcgg cgagcgccgc gaccagggcg tcccgctggg cggcgagctg ggcgcggcgg
    14701 gcggccacga tggcgggcgc ctcggcgagc aggtgcacgg cgacgagctg gtcgagcacc
    14761 gggctggcca tgtccacccc gacccgggcc gcggccagcc gctgcacctg gggcgcggag
    14821 gcgcggaccc agccgatccg caggccaccc cagtagggtt tgctcatccc gccgatgctg
    14881 atcacccggg agtgcctgtc gaagaccgcc acgggtggcg gcagcggggt gtcgtccagc
    14941 ggcaggtcga cgaaggactc gtcgacgacg aggtcggtgc cggccgcgtg ggccgcgccg
    15001 accagccgtt cgcgcaggtc ggccgccatc aggtggccgg tcgggttgtg gaactccggg
    15061 atcacgtacg cgagcttcgg ccttgtctgc cggatgctgc cgagcagcag ctcggcgtcc
    15121 cagccctcgt cggacaggcc gtgggtggcg atccgggcgc gccgggcgga cagcgcggcc
    15181 agggcgttgg ggtaggtggg tgactcgacg agcaccgcgc cgccgggcga cagggccagt
    15241 cgcagcacca ggtccagcgc gtgctgggtg ccgctggtga ccatgatctg ctccgggctg
    15301 gtgggcagcc cgcgctcggt gtacccgcgg gccaccgcct cccgcagctc gatgatgccg
    15361 gtcgggtggt agccggcgcc gcccaggtag cgggggaggt cctcggcggc cgcccgggcg
    15421 gccgggacga gctgcggcgg cgcggacagc gcggccacgc cgaggtcgat catgtcgcgg
    15481 tcgtccagcg gcgtccacag cccggtgctg gccacccggt ggccgccggg cagcatggtc
    15541 cagctcccgg cgccccggcg gctggccagg tggccgctct cccgcagttc ccggtacgcg
    15601 gcggtgacag tggtccggct gatccgcagc gcctcggcca gttcccgctc ggccggcagg
    15661 cgtaccccca gcggcagccg gccgtcggcg agcaggcccc ggacggcggc ggcgagcgcg
    15721 gcgtagtcgg ggctgcgccg gcggcccggc aatgcgtgcc actggccgag gagtcgcgcc
    15781 aattggacgc cgcgcacctg gctggtcatg gccacacctc cagaattggc ccccttgcgg
    15841 cctgcaattg gcccctaggg tggcatgcat ggcaccgctt ggcaatctcg ggcaccgccc
    15901 ggcgcgacga ctcacccagc tctacgccgg gctcgttctg tacggcctca gcatggcgct
    15961 gatgatccgg tcggagctgg gactggaccc gtgggacgtg ttccaccagg ggctctcccg
    16021 gcagaccggt ctctccttcg gcaccgtcac catcgccgtc ggcgctctcg tcctgctgct
    16081 ctggatcccg ctgcggcagc ggcccggcct cggcacggtc agcaacgtcg tggtgatcgg
    16141 gctggtcgtc gacgccacgc tcgcagtgct gccgcccggt gacggcatgc cggcgcgcgc
    16201 cgcgatgctg gtggccggga tcgtcgccaa cggcgccgcc accgggctct acctcggcgc
    16261 cgggctcggc cccggacccc gcgacggtct gatgaccggc ttcgtcgccc gccacccccg
    16321 cttctcggtc cggctggtcc gcacgagcat cgagatcacc gtgctggccc tcggctggct
    16381 gctcggcggg cccgtcggtc tcggcaccgt ggcgtacgcg ctcaccatcg gcccgctcgc
    16441 ccagttcttc atcccggtct tcgcgctgcc cgcgcggccg ccgcgcggcg cttacgctac
    16501 gtgatcagcg ccgggccgac cgccacggcc cgcagccctc cgcaacgcgc tgagctgcgg
    16561 tgacacagaa cagcgaaacc aggtgtttcc tccgccgtcg cggccgggca tcattcctgc
    16621 atgggggaga acggatggcg ttggagcgac gcctggatct tcgtcgcgtt ggtcatcgcc
    16681 agtggcgccg gccggcaccg gcggtccgcg tcgacacgcc gccccgaagg cgtacggctg
    16741 gccgatgtcc tctccacagc cgaccacctc aaccaggcca ttcccgagcg gcacgaggtg
    16801 gagggcgcgg tccggcggct cgtcggcgcg ggcctggtca gcgtctccga cggctggttc
    16861 cgggtcaccc cggacggtga gcagctctgg cgcacccgtc ccagcgccgg gctcggcacc
    16921 actgtggaca cggtgcaggg cgtgctgacc cgccggcacc cgcccggcga gtccgagtgg
    16981 cagctcgacg aggacgacca cgccgccgcg gtgcaggagt acgtggtccg ctcgatcccg
    17041 atgccgcgcc gctcccccga ggggcgatcc ggccggcagt gaccgcccgc ctcagcgcac
    17101 cgggtgcccg gcgccgcgca gcgcgtcctt gacctggccg acggtcagct cgccgaggcg
    17161 gaagacgctc gcggcgagca ccgcgtccgc tcccgcgccg acggccggcg ggaagtgtgc
    17221 cacctcgccc gcgccgccgc tggcgatcac cggcacgtcg accacctccc gcaccgcctg
    17281 gatcagcggc aggtcgaacc cggccttggt gccgtcggcg tccatcgagt tgagcaggat
    17341 ctcacccgcg cccagctcgg cgccgcgcgc cgcccactcg accgcgtcca ggccggtgcc
    17401 gcgccgcccg ccgtgcgtgg tcacctcgaa gccgctcggc gtcgtgccgt ccggggcgcg
    17461 gcgcacgtcc agcgagagca cgagcacctg gcgaccgaac cggtcggcga tctcggcgat
    17521 cagctccgga cgggcgatgg cggcggtgtt cacgcccacc ttgtccgccc cggcccgcag
    17581 cagcgtgtcg acgtcggcga cctgacggac gccgccgccc accgtgagcg ggatgaagac
    17641 cgactcggcg gtgcgccgca ccacgtcgag catggtgccc cggtcgctcg acgaggcggt
    17701 gacgtcgagg aaggtcagct cgtccgcgcc ggcccggtcg tacgccgccg ccagctccac
    17761 cgggtcgccc gcgtcgcgca ggtcgaggaa gttgaccccc ttgaccacgc gcccggcgtc
    17821 cacgtccaga cacgggatga cccgtaccgc caccgtcatg ccccgagcct aaccaccgcc
    17881 cgtggtggtg tgcgttcgcg ccggtcagag acgaaccagc atcttgccga ggttctcgcc
    17941 gcgcagcagg ccgaggaacg cctccggggc ctgctcgatg ccgtcgatca ccgtctcgtc
    18001 gtacgacagc cggccctcgc gcagccagcc cgccacctcc tgcacgaact gctcccgcag
    18061 gtgaccgtgg tcactgacga ggaagccgcg cagcgtcagg cgcttgccga tcaccagcgc
    18121 caggttgcgc ggggcggccg gcggctcggt ggcgttgtac tgcgcgatca tgccgcagat
    18181 ggcggctcgg ccgtgcaggt tcatcgcccc gatcgcggcc tccaggtggt cgccgccgac
    18241 gttgtcgaag tacacgtcga caccgtccgg ggcggcagcc ctgagctgct tggacaccgg
    18301 gccgtcgtgg tagtcgaacg cggcgtcgaa gccgagcgcg gtgagccgtt ccaccttggc
    18361 gcgggagccg gcgctgccga tcacccggcc ggcgccgcgc agcttcgcga tctggccgac
    18421 catgctgccc accgcgccgg ccgcgccgga gacgaacacg gtctcccccg gcttcatggc
    18481 ggccacgtcc agcagcccgg cgtacgcggt cagcccggtc atgccgagca cgcccaggta
    18541 cgcggtcacc ggtgccaggt cggggtcgac cttgcgtgcg ccccgggcgt ccacgagcgc
    18601 gtactcacgc cagccgagcc cgtgcagcac gacgtcgccg ggcttgacgc ccccggcctc
    18661 gccggccacc acctcaccga tcgcgccccc gtcgagcggg gcgtcgagcg cgaacggcgg
    18721 cacgtacgac ttgacgtcgt tcatccgccc gcgcatgtac gggtcgacgg acatgaaccg
    18781 gttgcggacc acgacctggc ccgggcccgg cgtcggcacc tcggtggtga ccagccggaa
    18841 gttctccgcg gtcggccagc cctgcggccg ggacgccaga tggatctccc ggttcaccgg
    18901 gcctcgcgga ccgtgcgggt gacctcgacg ttgccacggg tcgcgttgga gtaggggcag
    18961 acctggtggg ccgcgtcgac gagctgctcg gcggccgagc gctcgaccgc gggcaggtcc
    19021 accacgagcg tcacggccag gccgaagccg ccgctgccgt tcgggccgat gcccacctcg
    19081 gcctcgacga ccgaaccgga gacgtccgcc ttcgccttgc gggcgaccac gcgcagcgcg
    19141 gagtggaagc aggccgcgta gccggccgcg aagagctgct ccgggttggc cgcgccgccg
    19201 gcgccgccca tctccttcgg tacggcgagg tccagctcga cggtgccgtc ggaggtgcgg
    19261 acgtgaccgt cgcggccgtc gccggtggcg cgggcggagg cggtgtagag cacctgcatg
    19321 tcactgctcc ttctgtcggt ggatcgtctc ggtgacccgg gtgaggatgc cgtggaggaa
    19381 gaccagttcg gtctcggtga gcccggtggc ggtggccacc tgccgcggca cgtcgcacat
    19441 ccgctcccgc agggcccggc cctggtcggt gaggcccacc tcgacccggc gctcgtcggc
    19501 ggccgagcgg gtacgcacca ccagcccggc cgcctccagc cgcttgagca gcggggagag
    19561 cgtgccggag tcgagccgga gcgcggcgcc gagctcggag accgtggggg cgtcgtcgta
    19621 gcgctcccag agcaccagca gcaccaggta ctgcgggtag gtcaggccgt gctcgtcgag
    19681 gatgggccgg tagacgtcgg tcagggcgcg cgacgccgcg tagagggcga agcacacctg
    19741 ccggcgcagc accagatcat cggtcaccgc aaaaccgtaa cgcacaatta agttgtgcac
    19801 aaccgattgg cgcgcggtcc ggggcgggcg acgcgcccgg caccgtcagc cggcggggag
    19861 atacgcctcc agctcgacct cgaccagcat gtccgggtcg atcagcccgg ccaccaccac
    19921 catcgtcgcc accgggcgca ccggaccgaa caccgcgttg tgcgcccggc ccacctcgtc
    19981 ggcgtagatc cggtcggtca cgtacatccg ggtccgcacc acgtcgcccg gcccggcgcc
    20041 gacctcggcc agcgcgtcca ggccgatccg gatcgcctgc gcggtctgcg ccgccgcgtc
    20101 gcccgcgtgc gccacccggc cgtcgactgt ggaggtgcag ccggccgtga tcgccagcga
    20161 accggcccgg accacccggg agtagccgta cagcgcctcc cacgggccgc ccgagccgag
    20221 ccgggtcacc accccggcgt ccacgggcgg ctcggccgtc acgcgccggc ccgcaacgtg
    20281 gccagcgcct cggcgacggt gaacgcgccc gcgtagagcg ccttcccggc gatcacgccc
    20341 tccacgccca ccggctccag cgcggccagc gcccgcaggt cgtcgagcgt ggacacgccg
    20401 ccggaggcga tcaccggggc gtcggtccgc ccacacacct cgcgcagcag gtccaggttc
    20461 ggcccgcgca tggtgccgtc cttggtgatg tcggtgacca cgtaccgcgc cgcgcccgcc
    20521 gcgtcgagcc gggccagcac ctcgtagagg tcaccgccgt cgcgggtcca gccgcgcgcc
    20581 gacagggtac ggccgcgcac gtccagcccg atcgccaccc ggtcgccgta ctcgccgcag
    20641 atccggtcgc accactgcgg gtcctccagc gcggcggtgc cgatgttgac ccgggccgcc
    20701 ccggtggcca gcgccgcccg cagcgactcg tcgtcccgga taccgccgga cagctccacc
    20761 tgcacgtcca gcttgccgac cacctcggcc agcagcgcgg cgttggagcc ccgcccgaac
    20821 gcggcgtcca gatccaccag gtggatccac tccgcgccgt cggactgcca ggccagcgcc
    20881 gcgtccagcg ggtcgccgta ggtggtctcg ctaccggcgg cgccctgcac gagccggacg
    20941 gcctggccgt c
//
