LOCUS       NZ_CP030865            21098 bp    DNA     circular CON 14-AUG-2024
DEFINITION  Micromonospora sp. B006 chromosome, complete genome.
ACCESSION   NZ_CP030865
VERSION     NZ_CP030865.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sp. B006
  ORGANISM  Micromonospora sp. B006
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Complete Genome of Micromonospora sp. Strain B006 Reveals
            Biosynthetic Potential of a Lake Michigan Actinomycete
  JOURNAL   J Nat Prod 81 (9), 2057-2068 (2018)
   PUBMED   30110167
REFERENCE   2  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2018) Medicinal Chemistry and Pharmacognosy,
            University of Illinois at Chicago, 900 S Ashland Ave, Chicago, IL
            60607, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 77.6x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003408515.1-RS_2024_08_14
            Annotation Date                   :: 08/14/2024 03:31:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,342
            CDSs (total)                      :: 6,278
            Genes (coding)                    :: 6,199
            CDSs (with protein)               :: 6,199
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 20 of 79
            Pseudo Genes (incomplete)         :: 62 of 79
            Pseudo Genes (internal stop)      :: 6 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:07:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3609741
            Orig. end                         :: 3630839
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="14"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21098
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11098](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11098)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(490..1941)
                     /gene="argG"
                     /locus_tag="MicB006_RS15990"
                     /old_locus_tag="MicB006_3216"
     CDS             complement(490..1941)
                     /EC_number="6.3.4.5"
                     /GO_function="GO:0004055 - argininosuccinate synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042803 - protein homodimerization
                     activity [Evidence IEA]"
                     /GO_process="GO:0006526 - arginine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="argG"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1291: argininosuccinate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020661635.1"
                     /locus_tag="MicB006_RS15990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3216"
                     /product="argininosuccinate synthase"
                     /protein_id="WP_116507134.1"
                     /transl_table=11
                     /translation="MSKVLTSLPIGERVGIAFSGGLDTSVAVAWMRDKGAVPCAYTADI
                     GQYDEPDIASVPGRAHTYGAEVARLVDCRAALVEEGLAALTCGAFHIRSGGRAYFNTTP
                     LGRAVTGTLLVRAMIADDVQIWGDGSTFKGNDIERFYRYGLLANPQLRIYKPWLDTDFV
                     TELGGRTEMSEWLLERGLPYRDSTEKAYSTDANIWGATHEAKTLEHLDTGIETVEPIMG
                     VKFWDPSVEIPTEDVTIGFDQGRPVTINGKEFGSAVDLVLEANAIGGRHGLGMSDQIEN
                     RIIEAKSRGIYEAPGMALLHAAYERLVNAIHNEDTLANYHNEGRRLGRLMYEGRWLDPQ
                     ALMLRESLQRWVGTAVTGEVTLRLRRGEDYSILDTTGPAFSYHPDKLSMERTQDSAFGP
                     ADRIGQLTMRNLDIADSRAKLEQYASVGMVGGGNPQRVVGAAQAASTGLIGAMPQGGAE
                     AIASRGVPTAEDEALDRAAMEFGVD"
     misc_feature    1963..1976
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            complement(1986..2798)
                     /locus_tag="MicB006_RS15995"
                     /old_locus_tag="MicB006_3217"
     CDS             complement(1986..2798)
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0001510 - RNA methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018825869.1"
                     /locus_tag="MicB006_RS15995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3217"
                     /product="RNA methyltransferase"
                     /protein_id="WP_225980818.1"
                     /transl_table=11
                     /translation="MVPVHEITDPDDDRIADYRALTDVELRTRWEPPHGLFIAEGELVL
                     RRALRAGYPARSYLVDAKRVDQLADLDTGDTPVYAATPDVLQRATGFHVHRGVLASFHR
                     RPLPSADEVLAAARRVVILEDVNNHTNLGAIFRGAAALGVDAVLLSPTCADPLYRRSVR
                     VSMGEVFAVPYAKLDSWPAGLDQVRAAGFTVLAMTPAPDAVPMQRLTPAQRGRAALLLG
                     AEGPGLTAAAQAASDVRVVIPMRRGVDSLNVAAAAAVAFWELGRDDLL"
     gene            2899..4731
                     /locus_tag="MicB006_RS16000"
                     /old_locus_tag="MicB006_3218"
     CDS             2899..4731
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287358.1"
                     /locus_tag="MicB006_RS16000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3218"
                     /product="thiamine pyrophosphate-requiring protein"
                     /protein_id="WP_116507136.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 3.6e-37, bitscore:
                     126.1, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-23, bitscore:
                     82.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGADHDGNLPRDATVADYLVARLAEWGVHRYYGYPGDGINGMTSA
                     LQRAEGRARFIQVRHEETAGFAAGAHVKYGGGPLGCVVVTSGPGAIHALNGLYDAKLDH
                     QPVVALLGHTALPAEGGGYYQEVDLLSLYKDVASAFLAQLDDPSQARHLVDRACRTALA
                     RRTVTALVLPSDVQDLPAVPHPPHAHGYYHTSAVPSSTPTVPPEADVRRAAEVLRGGER
                     VAMLVGQGALGAEDEVRRIADRLGAGVATALLGFAAVDHRQPWVTGAIGLLGSRPSWQL
                     MRECDRLLIVGSQMPYSEFYPPEGQARAVQIDIDGTRMGLRYPTEVNLTGDAGPTLRAL
                     LRELGPGPGPTAWRATIADATGKWRASQREVAAQPADPVNPQSLFATLDDALPGDAMLA
                     VDCGTATAWYARHVRVRPGMLASLSGTLLSMGGGMPYALAAKFAHPDRPVIALLGDGAM
                     QMNGVNELITVAKYWREWSDPRFVVLVLNNRDLAFVSWEQRSGEGTPMFPDSQDLPDVA
                     YHRWAEVLGLGGELVDSAGRVGGLWQRVLDADRPVVVNAVVDPAELMLPPHFTAEQARK
                     TAAAAGRGDSDRAGIVRRGVPAVLATYRPRRRGR"
     gene            complement(4736..5296)
                     /locus_tag="MicB006_RS16005"
                     /old_locus_tag="MicB006_3219"
     CDS             complement(4736..5296)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475949.1"
                     /locus_tag="MicB006_RS16005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3219"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_116507138.1"
                     /transl_table=11
                     /translation="MGTVIYWVHTSVDGFIEGPNGEFDWPEMGEELSAYSMDLSERAAA
                     FVYGRRVWEMMAAYWPQVESISDHPHDLAFAPIWRRTPKVVVSRTLAEAGHGAVVVGGG
                     DLAKEFAEVRERFPGDLLLTGGTGAATALAALGLVDEFQVIVHPVVLGGGRQVLPGLAR
                     QSLRLVGTRTFDGRSVLLRYARA"
     gene            complement(5440..8520)
                     /locus_tag="MicB006_RS16010"
                     /old_locus_tag="MicB006_3220"
     CDS             complement(5440..8520)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="MicB006_RS16010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3220"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_161565933.1"
                     /transl_table=11
                     /translation="MFRLLGPVEVCFDDRTVRVGGPRSQAMLAALLLEANRIVPVSRLM
                     DAAWGSHPPASADVQVRNRVAAARRALRAAGLPGDVIGTHGSGYLLTVADGQLDLDVFE
                     ERVRRAEGRLDQGGAPEEALSGLREALAMWRGPALDGLRTPALTAAAQRLDERRMTVVE
                     RCLGLELGLGRYDSVIGRLTELVEAYPWRESLVGQLMRALYLADRQGEALDRFDQLRRR
                     LAEELGVDPTAQLTRLRDLILRNDPSLRAAPDAGPVVAPPDRPAASGTRPAAAAQHGAA
                     GPDGAARPPVRMLPAGLTDFVGREEQIAAVLEWLPDRPAVAVTAISGLPGVGKTTLAVR
                     IAHQLGAAYPGPHLYVDLNGHDHPSPPVEVLGRFLRALGVPGAEIPADLEERAALFRGA
                     MAERPGLVLLDNAADAAQVRPLLPGTDTVVLVTSRRALVDVDGAYQLRLDPLPEADALR
                     LLAGIIGADRVAAEPGSASDVVHHCGLLPLAVRIAGARLAIPGVPSLRQAAAQLAELSH
                     RLDHLTRADRSVRAAFHSAYVALDEPARRLLRRFAVLDLDRAPPWLPGVLLDDEAGAAD
                     AVTGLVEANLVEVTGPDELGQVRYHLHDLVRAFARERAAREEGPRERPEVLRRVFGTWL
                     TLVEQARVALSHEGGAAIVADLPRSPAPTGEHLSDPKRWFSAERAALLDSVEQAAATPG
                     LEDYSWALAWHCDYYLFVDARLDELTRVTETGLAAAERRRHPEGIARLRLCVAFAALLR
                     SDLEAALGYAQAAAAAAEPLAQPWLRADIAGVENQVYEGLGDRASARASLVRSIELYQE
                     AGDEVAAGPKLVRLGVLQLQEGDPAAGDTLARAVALLRAAGTPRPLAFGLRASGRWHDH
                     RGAVDEARAAYLEALDLVRRHGDRLGEVALLSEVAAMLAGHGRLGEAAGYADTALEQAR
                     KTRVAAYLAYARYAQGRISLMSGEPARARVLLEQAADDLTASPPLQVEALMDLARAVER
                     LTGAEAARDVWRRAHAVAARIGATATADEIERRLAGP"
     gene            complement(8683..9990)
                     /locus_tag="MicB006_RS16015"
                     /old_locus_tag="MicB006_3221"
     CDS             complement(8683..9990)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MicB006_RS16015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MicB006_3221"
                     /product="hypothetical protein"
                     /protein_id="WP_116507140.1"
                     /transl_table=11
                     /translation="MTTTGTEAAPDLSAATRVRFHPLRIRPSDDDPDSVVVGRPEVGEF
                     VELPAIGARAVELLDGGAPIGVAEERIAAEHDVDLDLVDLVLALREAGLVAEVDGRPTG
                     GARREDRPHLPWLRARHVRWLFGPAAKVAYVALVAATLATVVRRPELLPSYRDFFWTGY
                     VGLAVLVNTALFSVTAVLHEFSHLVAARSLDAPARIRFATRLHHLVLETDVTAIWSVPR
                     RHRYRVYLSGLLWDFAVVCAALLVMAYARPHPLVDGLLSAVVLVIVMSMALQLHVYMRT
                     DCYFVLLDLLRCRNLFQDGFAYARHLLRRGLHAAFPGRVAASAGDPTGVLPPHERRAVR
                     IYALAVVAGSAVALSSFVLFGIPIVAHGAIQAGSAVLAGATGGSLLAAVDGALVLLVEG
                     TLQAMFLVTFYRRHSRRRRAWAASGPAPHTAPEPIG"
     gene            complement(10001..11098)
                     /locus_tag="MicB006_RS16020"
                     /old_locus_tag="MicB006_3222"
     CDS             complement(10001..11098)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /locus_tag="MicB006_RS16020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3222"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_073831335.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 4.9e-29,
                     bitscore: 98.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1e-37, bitscore: 128.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKPRIKSVHEPYTLPGNRLIIGLMQYGVASEIQDDEDGTIARIL
                     TLLDGTRYVWEVCADLAETHPGIDEDSVREVVDQLIAQGFVEDAAAPLPDGFTVEAAQR
                     YDRARHFYAWIDTQPRRSPFEVQARIGRARVSVLGLGGTGTAVAAGLVASGVGGLHCAD
                     FDVIDQPNLTRQLLYTESDLGQPKVKVAVDRLRAMNSHVEVTGEECRVRSADDLVPLMN
                     GRDAFVLCADRPVDQIQDWTNEAALRTGTPWFMALYTGPMTVVGSFLPGRTGCYTCLRR
                     RPDKHEIQTDGTPLRGGERPNAVIAATANVTGHLCALEVLYYLGGLPQQVAGRVFHQNA
                     ARWDHHYFIDVPRDPDCPSCGPRGA"
     aSDomain        complement(10811..11098)
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_MicB006_RS16020_Pantocin_Microcin_RRE
                     .1"
                     /evalue="2.20E-31"
                     /identifier="RREFam017.1"
                     /label="MicB006_RS16020"
                     /locus_tag="MicB006_RS16020"
                     /protein_end="96"
                     /protein_start="0"
                     /score="98.9"
                     /tool="antismash"
                     /translation="MLKPRIKSVHEPYTLPGNRLIIGLMQYGVASEIQDDEDGTIARIL
                     TLLDGTRYVWEVCADLAETHPGIDEDSVREVVDQLIAQGFVEDAAAPLPDG"
     misc_feature    11369..11384
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.79"
                     /tool="antismash"
     gene            11433..12044
                     /locus_tag="MicB006_RS16025"
                     /old_locus_tag="MicB006_3223"
     CDS             11433..12044
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014299.4"
                     /locus_tag="MicB006_RS16025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3223"
                     /product="thymidylate kinase"
                     /protein_id="WP_116507142.1"
                     /transl_table=11
                     /translation="MARPVMIALIGVDGSGKTTQAKALAERLRRRGVRARYFENAGGRP
                     LWNRLARALGRTDGVALFGRTVYPALEATVRAAAMARTVAVARLTGRVAVLDRWTWCQD
                     VIMAARGDRGRRVVRAAYAVFPRPAVVCFLATSPEVARQRVAARGIDTEELAHLCALDA
                     AYRALPEFGSFVTLDGDGTPDEVAAALDAAVAAIVVPARH"
     misc_feature    complement(11457..11470)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.71"
                     /tool="antismash"
     gene            complement(12114..14315)
                     /locus_tag="MicB006_RS16030"
                     /old_locus_tag="MicB006_3224"
     CDS             complement(12114..14315)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018827420.1"
                     /locus_tag="MicB006_RS16030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3224"
                     /product="transglycosylase domain-containing protein"
                     /protein_id="WP_225980386.1"
                     /transl_table=11
                     /translation="MPSPRSPLSRLFTVLLAGLLAGLVLAVAALPAGLLGGFAARAALG
                     AYADLPDALRTPAQPQRSYLYANDGKTLITTFYDVNRTDVSLDEIAPVMRQAIIAAEDR
                     RFYSHGGADLRGIARALVANVKGGGTEQGGSTLTMQYVRNVLKTDPNRTAEERQAATEQ
                     TVGRKLQEIRYANALEQSLSKDEILNRYLNIAYFGSGAYGVAAASQRYFGKAPADLTLG
                     EAALLAGLVQSPEAYSPIDGDLDQALARRAYVLDAMAETGAITAQQAAAAKAQAPTLRP
                     TAQPNGCTATAQGHDDWGFFCDYLRRWWLTQPAFGSTPEEREQALRRGGYRVVTTLDPA
                     IQETAQEQATKVYGYGNKRALPIAAVEPGTGRVLAMAVNRHYSLDDNPAGQANYPNTVN
                     PLISGGASVDGYQAGSTFKMFTMLAALEAGKPLSTGFDAPSRLPTRYASDDEGNCDGTW
                     CPANANPQWMDGYRMMWDGFGRSVNTYFVWLAEQVGEDKVVEMAQRLGITFRAGSDAAF
                     ARDHAADWGAFTLGVAATTPLDLANAYATVAAEGTYCAPLPVVSVTTPDGGTVDVGQPE
                     CKRVLEPDVARAATDAARCPVGQQSAFEQCNGGTATAVDRIVGRPVAGKTGSSERNATE
                     TFVGYTPQVAVAGIAANPDDVTDLVGSAVQAKVIDAVARTIRTAVTGEPERDFTAPSRK
                     LVGDPQRPQPPRRTEPDRREQREDRELPSDVLRWLRDRG"
     misc_feature    14364..14378
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.97"
                     /tool="antismash"
     misc_feature    14367..14382
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.49"
                     /tool="antismash"
     misc_feature    complement(14395..14410)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.92"
                     /tool="antismash"
     gene            complement(14407..15210)
                     /locus_tag="MicB006_RS16035"
                     /old_locus_tag="MicB006_3225"
     CDS             complement(14407..15210)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788357.1"
                     /locus_tag="MicB006_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3225"
                     /product="hypothetical protein"
                     /protein_id="WP_116507146.1"
                     /transl_table=11
                     /translation="MKDPANRLFSRTPVPGAHDPAGPIGSRRTGGGFGVLPFVSESGRG
                     APATDATWAWSVRRFARAAVWLLPAYAVLYGLVAMASDGGVGNDPYPADGRPLYLVGWV
                     ASVWLGLLALLALTGLLAATRCRRIALAGLLCSIGGMVLMLPFAGLAEQTPVFGVTARG
                     IVLFGATLYSVGWFLTGWSVARSGMFSYGDGTMLMIAAPLLGLGGALIGSLQTFGAIFV
                     LVAGIGIGYRSGRLVPETIARDAAAASVAAAPVPPASPKGPLGAG"
     gene            complement(15339..16445)
                     /locus_tag="MicB006_RS16040"
                     /old_locus_tag="MicB006_3226"
     CDS             complement(15339..16445)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183342.1"
                     /locus_tag="MicB006_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3226"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_116507147.1"
                     /transl_table=11
                     /translation="MEFLAILMIAVALIGVVTLFKAVRIVPQQRQGVVERLGRYKRTLN
                     PGLNLLVPFVDAVRTKVDMREQVVSFPPQPVITSDNLVVSIDTVLYFKVVDSVRATYEI
                     SNFLQAIEQLTVTTLRNVIGSLDLERALTSREEINRHLSGVLDETTGRWGIKVTRVEIK
                     AIEPPPSIRDSMEKQMRAERDRRAAILNAEGHKQSQILTAEGEKQAAVLRADGDRQARI
                     LQAEGQAKAIRTVFDAIHTANPSQKVLAYQYLQALPQIANGTANKVWIVPTELTKALEG
                     MGGALGGLANMVGDQPSPEAAKSAGEVEREAAEAAQAAAIAAQEIHDEVRVAEAQATGG
                     NTPQGLPAPEPVSPASLVNDPADQRERG"
     gene            complement(16451..16924)
                     /locus_tag="MicB006_RS16045"
                     /old_locus_tag="MicB006_3227"
     CDS             complement(16451..16924)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018740695.1"
                     /locus_tag="MicB006_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3227"
                     /product="NfeD family protein"
                     /protein_id="WP_073831339.1"
                     /transl_table=11
                     /translation="MDAVFWIVLGVVLAVAEIFTTTLFLIMFGVGAFAAAGAAALGAPV
                     ALQAVIFAVVSALSVAVVRPVVRRHARPAIETGEQPFGVEALEGATAVVLEPVDAERGM
                     IKIDGELWTARSYDATRAYAEGERVQVIKVRGATALVWQDDISPPGELPEAKR"
     misc_feature    complement(16886..16888)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17023..18333
                     /locus_tag="MicB006_RS16050"
                     /old_locus_tag="MicB006_3228"
     CDS             17023..18333
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475945.1"
                     /locus_tag="MicB006_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3228"
                     /product="serine hydrolase"
                     /protein_id="WP_116507149.1"
                     /transl_table=11
                     /translation="MALLPETARQVDLLVARAQAEGRGPSLALGVIRDGRLAHLAVAGE
                     TPRPDADLQYRIGSITKTMTAVLVMQQRDAGRLALDDPLDAHLPGTPVGSVTVRRLLGH
                     VSGLQREPDGQWWERTEGADLPTLLAGLTPDKIAHPPHFVYHYSNLAYGLLGGVLERIT
                     GTPWAELLTERLLAPLGMRRTTYHPTEPYAPGYVVHPWHETLREEPLTDSGAMAPAGQL
                     WSTVEDLGRWASFLADPDPALLSPATLTEMCAPMVINDLDSWSGGHGLGIELYRVGDRV
                     YVGHGGSMPGYVAGLAVHRPTRTAVVNFANSYGLRGHHIGALGREALTLVLDAEPAAPA
                     PWRPADPPAADVAALTGRWWWMGGEYEFRVDAAGELVGGQVGRPQLRFTPEGPDRWRGR
                     SGSQDGEILTVIRDGSGTPVALDIATFVLTRTPDELP"
     gene            complement(18871..19683)
                     /locus_tag="MicB006_RS16060"
                     /old_locus_tag="MicB006_3229"
     CDS             complement(18871..19683)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018251506.1"
                     /locus_tag="MicB006_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3229"
                     /product="DUF3097 domain-containing protein"
                     /protein_id="WP_073831341.1"
                     /transl_table=11
                     /translation="MAGRYDGDVLAGDWRRRKVTPEVDAEPDLVVEDADSGFCGAVVGF
                     DAGAVVLEDRHGRRRNFPLLPAAFLLDGRPVTLRRPARAPVPAARRRTASGSIAVDGVR
                     AQVAKASRIWVEGVHDAALVERIWGDDLRIEGVVVEPLDGIDALAEEVRAFAPGPGRRL
                     GVLVDHLVPGSKESRIVARVTSPHVLVTGHPYVDVWQAVRPAALGIAAWPVVPPGQPWK
                     EGVCAALGVAEPADMWRRILSRVDSFADVETPLINAMERLIDFVTEPV"
     gene            19845..20639
                     /locus_tag="MicB006_RS16065"
                     /old_locus_tag="MicB006_3230"
     CDS             19845..20639
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018788362.1"
                     /locus_tag="MicB006_RS16065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_3230"
                     /product="hypothetical protein"
                     /protein_id="WP_073831342.1"
                     /transl_table=11
                     /translation="MSSPAAGAATLAPRRSSRFVAWVRAWRAGLVPFDEVADAVAGDEE
                     HLVADAPGTWTDVSLREALPSLAKHSPDDIRLVLPAPGDPRGLPGPGAFAGAALVAGEA
                     VVASGMGLVPEVRTHTSGSGMTWETVLWRVHPLPADAPKASLSTPGAAEAEAELSAVLA
                     ETTATLTRLDVAQWRPELAGALAALRRPDGATDLPPGFDPRARRLFARAAVLDRVLALA
                     GESAPGGAVNTYEAQQRDAALRPLTTACRQALVAACNAPLRL"
     misc_feature    20660..20674
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
     misc_feature    20983..20996
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     misc_feature    20987..21003
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.53"
                     /tool="antismash"
ORIGIN
        1 tgagctgggc gtccacgatc aggccgtgga ccgcctcggt gatccggacg aacggggtgc
       61 cccggcgcaa ctcgaccagg ggcaggccgc ggcgttcggc ggcggcggcc atcacccggg
      121 gcacaccggt gaggtaccgg cggccgagct cgaccaccag tccggaggcg ccgacgtcgg
      181 ccagggtgcc gatgaactcg cgcagcccgg cgtcgtcggt cggcagcccg atcccggtgg
      241 tcaggaccag ctccccgccg cccagcaggg tggcgatgtc gggcacctcg gcgatgtgca
      301 cccaccgtac cggccggtcc agcccggcgt tcccggcgac caggcgcggc gcaccgtggc
      361 gcatgggcac caggtccagg acctcacgca cggtagggaa cacgggcgac acgctaccct
      421 gcgtcaccgt cgttgccgag ggccgcaccg gccggctcgc cggggaggac gagccggccg
      481 actgcgggat cagtcgacgc cgaactccat ggcggcccgg tcgagcgcct cgtcctcggc
      541 cgtgggcacg ccccgggacg cgatggcctc ggcgccgccc tgcggcatgg cgccgatcag
      601 cccggtcgag gcggcctggg cggcgcccac gacccgctgc gggttgccgc cgccgaccat
      661 gccgacggag gcgtactgct ccagcttggc gcgggagtcg gcgatgtcga ggttgcgcat
      721 ggtgagctgg ccgatccggt cggccgggcc gaacgccgag tcctgggtgc gctccatcga
      781 cagcttgtcc gggtggtagc tgaacgccgg gccggtggtg tcgaggatcg agtagtcctc
      841 gccccggcgc agccgcagcg tgacctcgcc ggtgaccgcc gtgccgaccc agcgctgcag
      901 cgactcgcgc agcatcagcg cctgcgggtc cagccagcgg ccctcgtaca tgaggcggcc
      961 gaggcgacgg ccctcgttgt ggtagttcgc cagcgtgtcc tcgttgtgga tggcgttcac
     1021 cagccgctcg tacgcggcgt gcagcagcgc catgccgggc gcctcgtaga tgccccggct
     1081 cttggcctcg atgatccggt tctcgatctg gtcggacatg cccaggccgt gccggccgcc
     1141 gatggcgttg gcctccagca ccaggtcgac ggcgctgccg aactccttgc cgttgatcgt
     1201 cacggggcgg ccctggtcga agccgatggt gacgtcctcg gtggggatct ccacggacgg
     1261 gtcccagaac ttcacgccca tgatcggctc gaccgtctcg atgccggtgt cgaggtgttc
     1321 gagcgtcttg gcctcgtggg tggcgcccca gatgttggcg tcggtggagt acgccttctc
     1381 ggtgctgtcc cgatacggca ggccgcgctc cagcagccac tccgacatct cggtgcggcc
     1441 gcccagttcg gtgacgaagt cggtgtccag ccacggcttg tagatccgca gctgcgggtt
     1501 ggccagcagg ccgtagcggt agaaccgctc gatgtcgttg cccttgaacg tcgagccgtc
     1561 gccccagatc tgcacgtcgt cggcgatcat cgcccgcacg agcagcgtgc cggtcacggc
     1621 ccggcccagc ggggtggtgt tgaagtaggc ccgcccgccg gagcggatgt ggaaggcgcc
     1681 gcaggtcagc gccgccagcc cttcctcgac cagggcagcg cggcagtcga cgagccgggc
     1741 gacctcggcg ccgtaggtgt gggcgcggcc gggcaccgag gcgatgtcgg gctcgtcgta
     1801 ctggccgatg tcggcggtgt aggcgcacgg gacggcgccc ttgtcgcgca tccacgcgac
     1861 cgcgaccgag gtgtcgaggc cgccggagaa ggcgatgccg acacgttcgc cgatgggcag
     1921 ggaggtgaga accttggaca caaggaagat tatgcaccct ctcgcatggt catgcaagcc
     1981 gtacgtcaga gcaggtcgtc gcgccccagc tcccagaacg ccaccgccgc ggcggcggcc
     2041 acgttcagcg agtccacgcc gcgccgcatc gggatcacca cccgcacgtc gctggccgcc
     2101 tgcgccgccg cggtcagccc cggcccctcc gccccgagca gcaacgccgc ccgcccccgc
     2161 tgcgccgggg tcagccgctg catcggtacg gcatcaggcg cgggcgtcat ggcgagcacc
     2221 gtgaacccgg ccgcccggac ctggtccagc cccgcgggcc agctgtcgag cttcgcgtac
     2281 gggaccgcga acacctcgcc catgctgacc cgtacgctgc gccggtagag cgggtcggcg
     2341 caggtcgggg acagcagcac cgcgtcgacg ccgagcgcgg cagcgccccg gaagatcgcg
     2401 cccaggttcg tgtggttgtt gacgtcctcc aggatcacca cccgccgggc ggcggccagc
     2461 acctcgtcgg ccgacggcag cggcctgcgg tggaacgacg cgagcacgcc ccggtgcacg
     2521 tggaagccgg tggcccgctg gagcacgtcc ggcgtggccg cgtacaccgg ggtgtcgccg
     2581 gtgtcgaggt cggcgagctg gtccacccgc ttggcgtcga ccaggtacga ccgggccggg
     2641 tagccggccc gcagcgcccg ccgcagcacc agttccccct cggcgatgaa cagcccgtgc
     2701 ggcggttccc agcgcgtacg cagctccacg tcggtgagcg cgcggtagtc ggcgatccgg
     2761 tcgtcgtcgg ggtcggtgat ctcgtggacg ggcaccaggc gattctgccc ggcccgcccg
     2821 gtcgccccgg cacgggccgg gtttccaccg ccccgggcgg ggaacggagc cgaaggccga
     2881 cgcgacggag ggaccacgat gggcgcggat cacgacggca acctcccccg cgacgccaca
     2941 gttgccgact acctggtggc ccggctcgcc gaatggggtg tgcaccgcta ctacggctac
     3001 ccgggcgacg ggatcaacgg catgacctcg gcgctgcaac gcgccgaggg gcgtgcccgg
     3061 ttcatccagg tccggcacga ggagaccgcc ggtttcgcgg ccggcgcgca cgtcaagtac
     3121 ggcggcggcc cgctcggctg cgtggtggtg accagcggcc cgggcgcgat ccacgccctc
     3181 aacggcctct acgacgccaa gctggaccac cagccggtgg tcgcgctgct cgggcacacc
     3241 gcgctgcccg ccgagggcgg cggctactac caggaagtgg acctgctctc gctctacaag
     3301 gacgtggcct cggccttcct ggcccagctc gacgacccgt cccaggcccg gcacctggtg
     3361 gaccgggcct gccgcaccgc gctggcccgg cgtaccgtga ccgccctggt cctcccctcc
     3421 gacgtgcagg acctgccggc ggtgccgcac ccgccgcacg cccacggcta ctaccacacc
     3481 agcgcggtgc cgagcagcac gccgacagtg ccgccggagg ccgacgtgcg ccgtgccgcc
     3541 gaggtgctgc gcggcggcga gcgggtggcg atgctggtcg ggcagggcgc gctgggcgcg
     3601 gaggacgagg tacgccggat cgccgaccgg ctcggcgccg gggtcgccac cgcgctgctc
     3661 ggcttcgccg ccgtcgacca ccgccagccc tgggtgaccg gcgcgatcgg cctgctcggc
     3721 agccgcccga gctggcagct catgcgcgag tgcgaccggc tgctaatcgt cggcagccag
     3781 atgccgtact cggagttcta cccgcctgag ggccaggccc gggcggtgca gatcgacatc
     3841 gacggcaccc ggatggggct gcgctacccg accgaggtga acctgaccgg tgacgccggg
     3901 ccgacgctgc gcgccctgct cagggagctg ggtccggggc cgggcccgac cgcctggcgg
     3961 gccacgatcg ccgacgccac cggcaagtgg cgggcctccc aacgcgaggt cgccgcccag
     4021 ccggccgacc cggtcaaccc gcagtcgctg ttcgccacgc tcgacgacgc gctgccaggc
     4081 gacgccatgc tcgctgtgga ctgcggcacc gccaccgcct ggtacgcccg ccacgtgcgg
     4141 gtccgccccg gcatgctggc cagcctctcc ggcacgctgc tctccatggg cggcgggatg
     4201 ccgtacgcgc tggcggcgaa gttcgcccac ccggaccgcc cggtgatcgc gctgctcggc
     4261 gacggggcga tgcagatgaa cggcgtcaac gagctgatca cggtggcgaa gtactggcgg
     4321 gagtggtccg acccccggtt cgtggtgctg gtgctcaaca accgggacct ggcgttcgtc
     4381 agctgggagc agcggtccgg cgagggcacg ccgatgttcc cggacagcca ggacctgccc
     4441 gacgtggcgt accacaggtg ggcggaggtg ctggggctcg gcggcgagct tgtcgactcc
     4501 gccggccggg tgggcggctt gtggcagcgg gtgctcgacg cggaccgccc ggtggtggtg
     4561 aacgcggtgg tggacccggc cgagctgatg ctgccgccgc acttcaccgc cgagcaggcc
     4621 cgcaagaccg ccgcggcggc cgggcgcggg gacagcgacc gggccggcat cgtgcgccgc
     4681 ggcgtaccgg cggtgctcgc cacgtaccgg ccccgccgcc gggggcgctg acccgtcagg
     4741 cccgcgcgta gcgcagcagc accgaccgcc cgtcgaaggt gcgcgtcccg accaaccgca
     4801 ggctctgccg ggccaggccg ggcagcacct gccgcccgcc gccgagcacc accgggtgca
     4861 cgatcacctg gaactcgtcg acgagcccga gcgcggccag cgccgtcgcc gcgccggtgc
     4921 cgccggtgag cagcaggtca ccggggaacc gctcgcggac ctcggcgaac tccttcgcca
     4981 ggtcgccgcc gccgaccacc acggcgccgt ggccggcctc ggcgagcgtg cgggagacca
     5041 cgaccttcgg ggtacgccgc cagatcggcg cgaacgccag gtcgtgtgga tggtcggaga
     5101 tcgactcgac ctgcggccag taggcggcca tcatctccca cacccgccgc ccgtagacga
     5161 aggcggcggc ccgctcggac aggtccatcg agtacgcgga cagctcctcc cccatctccg
     5221 gccagtcgaa ctcgccgttc ggcccctcga tgaagccgtc gaccgacgtg tgcacccagt
     5281 agatgacagt gcccatgatg tgttcctccg cgttgcggcg cgtcccggtc gggcgcgctc
     5341 gccggtgggt cggagccgtc cggccggatc cgacaacccg gccccgacga ctcccggccg
     5401 ggctgaccgc tcccggccgg ctggtccctc caggccaggc tacggtccgg ccagccgccg
     5461 ctcgatctcg tccgccgtgg cagtggcccc gatccgggca gccaccgcgt gggcgcgccg
     5521 ccagacgtcc cgggccgcct cggccccggt cagccgttcc accgcccggg ccaggtccat
     5581 cagggcctcc acctgcagcg gcgggctggc cgtcaggtcg tcggccgcct gttcgagcag
     5641 gacccgcgcc cgcgccggct cgcccgacat caggctgatc cgtccctggg cgtaccgggc
     5701 gtaggccagg tacgccgcga cccgcgtctt gcgggcctgc tccagggcgg tgtcggcgta
     5761 cccggccgcc tcgcccagcc ggccgtgccc cgcgagcatc gcggcgacct cgctgagcag
     5821 cgccacctca ccgagccggt caccgtgccg ccggaccaga tccagggctt ccaggtacgc
     5881 cgcccgggcc tcgtccaccg cgccgcggtg gtcgtgccag cggcccgacg cgcgcaggcc
     5941 gaacgcgagc ggccggggcg tgccggcggc ccgcagcagc gcgacggccc gggcgagcgt
     6001 gtccccggcg gccggatcgc cttcctgcaa ctggagtacg cccagccgga cgagtttcgg
     6061 tccggcggcg acctcgtcac cggcttcctg gtacagctcg atggagcgga ccaggctggc
     6121 gcgtgccgac gcccggtcac ccagtccctc gtacacctgg ttctcgaccc cggcgatgtc
     6181 ggcccgcagc cagggttggg cgagcggctc ggccgccgcg gcggcggcct gcgcgtagcc
     6241 gagcgcggcc tccaggtcac tgcgcagcag ggccgcgaac gccacgcaga gccggagccg
     6301 ggcgatcccc tcggggtgcc gccggcgctc ggcggccgcc agcccggtct cggtgacccg
     6361 ggtcagctcg tccagccggg cgtcgacgaa caggtagtag tcgcagtgcc aggccagcgc
     6421 ccaggagtag tcctccaggc cgggcgtcgc ggcggcctgc tcgacgctgt ccagcagggc
     6481 ggcccgttcg gcgctgaacc agcgcttcgg gtcgctcagg tgctcgccgg tgggcgccgg
     6541 tgacctcggc aggtcggcga cgatggcggc gccgccctcg tgactcagcg ccacccgggc
     6601 ctgctcgacc agcgtcagcc aggtgccgaa gacacgccgc agcacctccg gccgttcccg
     6661 cggcccctcc tcccgcgcgg cgcgctcccg ggcgaaggcg cggaccagat cgtggaggtg
     6721 atagcggacc tggcccagct cgtccggccc ggtcacctcg accaggttgg cctcgaccag
     6781 gccggtgacc gcgtccgccg cgcccgcctc gtcgtcgagc aggacgccgg gcagccacgg
     6841 cggggcccgg tcgaggtcca gcaccgcgaa ccggcgcagc agccgccggg ccggctcgtc
     6901 cagcgccacg tacgccgagt ggaacgccgc ccgtacgctg cggtcggcgc gggtgaggtg
     6961 gtccagccgg tgcgagagtt cggcgagctg cgccgccgcc tgccgcagcg acggcacgcc
     7021 gggtatcgcc agccgggcgc ccgcgatccg caccgccagc ggcagcagtc cgcagtggtg
     7081 gacgacgtcc gacgcggagc cgggttcggc agcgacgcgg tccgcgccga tgatgccggc
     7141 gagcagccgc agtgcgtccg cctcgggcag cgggtccagc cgcagctggt aggcgccgtc
     7201 gacgtcgacg agcgcgcgcc ggctcgtgac cagcacgacg gtgtccgtcc cgggcagcag
     7261 ggggcgcacc tgcgccgcgt cggccgcgtt gtccagcagc accagaccgg gccgctcggc
     7321 catcgcgccc cggaacagcg cggcgcgttc ctccaggtcc gcggggatct ccgcgccggg
     7381 tacgccgagc gcccgcagga accgcccgag cacctccacc ggaggcgacg gatggtcgtg
     7441 cccgttcagg tcgacgtaca ggtgcggacc ggggtacgcc gcgccgagct ggtgggcgat
     7501 ccggaccgcc agcgtggtct tgccgacgcc gggcaggccg ctgatcgccg tcaccgcgac
     7561 cgccggccga tccggaagcc actccaggac cgccgcgatc tgctcctccc ggccgacgaa
     7621 gtcggtgagg cccgccggaa gcatccggac cggcgggcgt gcggccccgt ccggtccggc
     7681 ggctccgtgt tgagcggcgg cggccgggcg cgttccggag gcggccgggc ggtccggcgg
     7741 cgcgacgacc ggcccggcgt cgggtgccgc ccgcaggctg gggtcgttgc gcaggatcag
     7801 gtcgcgtagc cgggtcagct gcgccgtcgg gtcgacgccg agctcctcgg ccaggcgacg
     7861 gcgcaactgg tcgaaccggt ccagcgcctc gccctgccgg tccgccaggt agagggcccg
     7921 catgagctgg cccacgagcg actcccgcca cgggtacgcc tcgaccagtt cggtgagccg
     7981 gccgatgacg ctgtcgtacc ggccgaggcc cagctccagg ccgaggcagc gctcgaccac
     8041 tgtcatccgc cgctcgtcga gacgctgcgc cgcggcggtg agcgccggcg tacgcaggcc
     8101 gtcgagcgcc ggaccgcgcc acatcgccag cgcctcgcgc agcccggaca acgcctcctc
     8161 cggggcgccg ccctggtcga gtcgcccctc ggcccggcgt acccgttcct cgaagacgtc
     8221 caggtcgagc tgaccgtcgg cgacggtgag caggtatccg gagccgtggg tgccgatcac
     8281 gtcgccgggc agaccggcgg cgcgcagcgc ccgtcgcgcc gccgcgaccc ggttgcggac
     8341 ctggacgtcc gcgctcgccg gcggatggct gccccacgcg gcgtccatga ggcgggacac
     8401 cgggacgatc cggttggctt ccagcagcaa cgcggcgagc attgcctgac tgcgcgggcc
     8461 accgacgcgg accgtccggt cgtcgaagca cacctcgacc gggccgagca gccgaaacat
     8521 gaccgccggc accattcgct ccccccgaag cgcgcggacc cgggcgacca cttcatgatc
     8581 gccctccggc cccaccctag acgagttcgc gcgaggtcag ggggtgacgc gtaccagcgg
     8641 tggccggggg gacgcaccac tgtggccggt cgtcgccgcc ggtcagccga tcggctccgg
     8701 cgcggtgtgc ggcgccgggc cggaggcggc ccacgcccgg cgtcgtcgcg aatgacgccg
     8761 gtagaacgtg accaggaaca tcgcctggag cgtgccctcg acgagcagga cgagcgcgcc
     8821 gtccacggcc gcgagcaggc ttccgccggt cgcgccggcc agcacggccg agcccgcctg
     8881 gatcgcgccg tgcgcgacga tcggaattcc gaacaggacg aagctggaca gcgcgacagc
     8941 gctgcccgcc accaccgcca gcgcgtagat ccgcaccgcg cgccgctcgt gcggcggcag
     9001 gacgccggtg gggtccccgg cggacgccgc cacccggccg ggaaacgccg cgtgcagacc
     9061 ccggcgcaac aggtgccggg cgtacgcgaa gccgtcctgg aacaggttgc ggcaccgcag
     9121 caggtccagc aggacgaagt agcagtcggt gcgcatgtag acgtgcagtt gcagcgccat
     9181 cgacatgacg atcaccagga cgacggcgga cagcagcccg tcgacgagcg gatgcggccg
     9241 ggcgtacgcc atcaccagca gcgcggcgca cacgacggcg aaatcccaca gcaggccgct
     9301 gagatagacg cggtaccggt ggcggcgcgg caccgaccag atcgctgtca cgtcggtctc
     9361 caggaccagg tggtgcagcc gggtggcgaa gcggatccgg gccggcgcgt ccagcgaacg
     9421 ggccgcgacc aggtgactga actcgtgcag aacggccgtc acggagaaca gcgcggtgtt
     9481 cacgagcacg gcgagaccga cgtagccggt ccagaagaag tcccggtacg agggcagcag
     9541 ctcgggacgg cgtaccacgg tggccagcgt cgccgcgacc agcgcgacgt aggccacctt
     9601 cgccgcgggg ccgaacagcc agcgcacgtg ccgggcccgc agccagggca gatgcggccg
     9661 gtcctcgcgg cgggcgccgc cggtgggccg gccgtcgacc tcggccacca ggcccgcctc
     9721 ccgcagcgcg agcaccaggt ccacgaggtc gaggtccacg tcgtgctcgg cggcgatccg
     9781 ttcctcggcc acgccgatcg gcgctccgcc gtcgagcagc tcgacggcgc gggcgccgat
     9841 cgcgggcagc tccacgaact cgccgacctc cggccggccc accaccaccg agtccgggtc
     9901 gtcgtcggac ggccggatcc gcagcgggtg gaaccgtacc cgcgtcgcgg cgctcaggtc
     9961 cggcgcggcc tcggtcccgg tggtcgtcat cgcccggtcc tcacgcgccg cgcggaccgc
    10021 acgaggggca gtccgggtct cgcggcacgt cgatgaagta gtggtggtcc cagcgcgcgg
    10081 cgttctggtg gaagacccgc ccggcgacct gctggggcag cccgccgagg taatagagca
    10141 cctccagcgc gcagaggtga cctgtcacgt tcgcggtggc ggcgatcacc gcgttcggtc
    10201 gttcccctcc gcgcagtggc gtgccgtcgg tctggatctc gtgcttgtcc ggccgtcgcc
    10261 gcaggcacgt gtagcacccg gtacggcccg gaaggaacga gccgaccact gtcatcgggc
    10321 cggtgtagag cgccatgaac cacggagtgc cggtacgcag ggccgcctcg ttcgtccagt
    10381 cctggatctg gtcgacgggc cggtccgcgc agaggacgaa ggcgtcccgc ccgttcatca
    10441 gcggcaccag gtcgtcggcg gagcggacgc ggcactcctc cccggtgacc tcgacgtgcg
    10501 agttcatcgc ccgcagccgg tccacggcga ccttcacctt cggctggccg aggtcgctct
    10561 cggtgtagag cagctggcgg gtcaggttcg gctggtcgat cacgtcgaag tcggcgcagt
    10621 gcaggccgcc gacgccgctg gcgacgagtc cggccgcgac cgccgtaccg gtgccgccga
    10681 gaccgagtac ggagacccgg gcccgcccga tgcgcgcctg aacctcgaag ggcgaacggc
    10741 gcggctgggt gtcgatccag gcgtagaagt gccgggcccg gtcgtagcgc tgcgcggcct
    10801 ccactgtgaa cccgtcgggc agcggggccg ccgcgtcctc gacgaagccc tgcgcgatga
    10861 gctggtccac cacctcgcgg acgctgtcct cgtcgatgcc cgggtgcgtc tcggcgaggt
    10921 ccgcgcagac ctcccacacg taccgggtgc cgtcgagcaa cgtcaggatg cgggcgatcg
    10981 taccgtcctc gtcgtcctgg atctccgacg cgacgccgta ctgcatcaga ccgatgatca
    11041 gccggttccc cggcagggtg tagggctcgt ggacactctt gatgcgcggc ttgagcatgg
    11101 gtaccgcaac ctcacaatgc tcggcggaag gcgggaaagc ggcaccccgg ccgccgccgg
    11161 tacgtggcgg cgaccggggt gccgacgcgg atcaggcgcc gttgctctcg cggatgacgg
    11221 tggtctccag ccgctccagc ttgcggacct tcagcgagag cttcttcttg ccggcctgct
    11281 cgatcgtggc cttctccatg gacgcctcct cgattcgggt acgccctccg cagtaccgcg
    11341 gaaggcgagc ccaagcctgt cgccaagcgt caccggtcga tcacaagtcg atcatcaacg
    11401 gccgttggcg ggcgccgcta gcatccgggt gcgtggcccg acctgtgatg atcgcgttga
    11461 tcggtgtcga cggctccggc aagaccaccc aggcgaaggc gctggccgaa cggctgcgcc
    11521 ggcggggtgt ccgggcgcgg tacttcgaga acgccggtgg gcggccgctg tggaaccggc
    11581 tggcccgggc gctcggccgg acggacgggg tggcgctgtt cggtcgtacc gtctatccgg
    11641 cgctggaggc gacggtgcgc gcggcggcga tggcccggac cgtggcggtg gcccgcctga
    11701 ccggccgggt ggccgtgctg gaccggtgga cctggtgcca ggacgtgatc atggcggccc
    11761 ggggcgaccg gggacggcgc gtggtgcgcg ccgcgtacgc ggtcttcccg cgcccggcgg
    11821 tggtgtgctt cctggccacc tcccccgagg tggcccggca gcgggtggcc gcgcgcggca
    11881 tcgacaccga ggaactggcg cacctgtgcg cgctggacgc cgcgtaccgg gcgttgccgg
    11941 agttcggctc gttcgtcacg ctcgacggcg acggcacgcc ggacgaggtg gccgcagccc
    12001 tcgacgcggc cgtggccgcg atcgtggttc cggcgcggca ttgagtcgtg cgtgcggggc
    12061 ggcgttaaga aggggcccct ttactaccgg aggcgttaag aaggggccct tccttacccg
    12121 cggtcgcgca gccagcggag cacgtcggag ggcagctcgc ggtcctcgcg ctgctcgcgg
    12181 cggtccggct cggtccgccg gggcggctgc ggacgctgcg ggtcgccgac gagcttccgg
    12241 ctgggggcgg tgaaatcgcg ctccggctcg ccggtgaccg ccgtcctgat ggtccgcgcc
    12301 accgcgtcga tcaccttcgc ctgcacggcg gagccgacca ggtcggtgac gtcgtccggg
    12361 ttggcggcga tgccggccac ggcgacctgc ggggtgtacc cgacgaacgt ctccgtggcg
    12421 ttccgctccg agctgccggt cttgccggcg accgggcggc cgacgatccg gtcgacggcg
    12481 gtggcggtgc cgccgttgca ctgctcgaac gcggactgct ggccgaccgg gcagcgggcc
    12541 gcgtcggtgg cggcccgggc cacgtccggt tcgaggaccc gcttgcactc cggctgcccc
    12601 acgtcgacgg tcccgccgtc gggcgtggtc accgagacca ccggcagcgg cgcgcagtac
    12661 gtgccctcgg cggccaccgt cgcgtacgcg ttcgccaggt cgagcggggt ggtggcggcc
    12721 acgcccagcg tgaacgcgcc ccagtcggcg gcgtggtcgc gggcgaacgc ggcgtcggag
    12781 ccggcccgga aggtgatgcc gaggcgctgc gccatctcca ccaccttgtc ctcgccgacc
    12841 tgctcggcga gccagacgaa gtacgtgttg acggagcggc cgaagccgtc ccacatcatc
    12901 cggtagccgt ccatccactg cgggttggcg ttcgccgggc accaggtgcc gtcgcagttg
    12961 ccctcgtcgt ccgaggcgta ccgggtgggc aggcggctcg gcgcgtcgaa gccggtggac
    13021 agcggcttgc cggcctccag cgcggccagc atggtgaaca tcttgaacgt cgagccggcc
    13081 tggtagccgt cgacgctggc gccgccggag atcagcgggt tgacagtgtt cgggtagttg
    13141 gcctgcccgg cggggttgtc gtcgaggctg tagtgccggt tcaccgccat ggcgagcacc
    13201 cggccggtgc cgggctcgac cgccgcgatc ggcagcgcgc gcttgttgcc gtacccgtag
    13261 accttggtgg cctgctcctg cgcggtctcc tggatcgccg ggtcgagcgt ggtgacgacc
    13321 cggtagccgc cccggcgcag cgcctgctcg cgctcctcgg gggtgctgcc gaaggcgggc
    13381 tgggtgagcc accagcggcg caggtagtcg cagaagaagc cccagtcgtc gtggccctgg
    13441 gcggtggcgg tgcagccgtt gggctgggcg gtcgggcgca gcgtgggcgc ctgcgccttc
    13501 gccgccgcgg cttgctgggc ggtgatcgct ccggtctcgg ccatcgcgtc cagcacgtac
    13561 gcccggcggg ccagcgcctg gtcgaggtcg ccgtcgatcg ggctgtacgc ctccggcgac
    13621 tggaccagac cggccagcag cgcagcctcg cccagcgtca ggtcggccgg ggccttgccg
    13681 aagtagcgct ggctcgcggc ggcgacgccg tacgcgccgg aaccgaagta cgcgatgttc
    13741 aggtagcggt tgaggatctc gtccttggac agcgactgct ccagcgcgtt cgcgtaccgg
    13801 atctcctgga gcttgcgccc gacggtctgc tcggtggcgg cctgccgctc ctccgctgtg
    13861 cggttcgggt cggtcttgag cacgttgcgg acgtactgca tggtcagcgt ggagccgccc
    13921 tgctcggtgc cgccgccctt gacgttcgcc accagcgccc gggcgatgcc gcgcaggtcc
    13981 gcgccgccgt gcgagtagaa ccgccggtcc tcggccgcga tgatcgcctg ccgcatcacc
    14041 ggggcgatct cgtccagcga cacgtcggtg cggttcacgt cgtagaacgt ggtgatcagc
    14101 gtcttgccgt cgttggcgta gaggtaggag cgctgcggct gggccggcgt gcgcagcgcg
    14161 tcgggcaggt ccgcgtacgc gccgagcgcc gcccgggcgg cgaacccgcc gagcagtccg
    14221 gcgggaagcg cggcgaccgc gaggacgagc ccggcgagca ggccggccag cagcacggtg
    14281 aacagccgcg acagcggcga cctgggagac ggcatggtcg caaggattgc cacgaaagcc
    14341 gcctaccggc cacctcgcca ggcaactgtc agttacttca cggcgaccgc ccagctgaag
    14401 aaacggtcag cccgccccga gtgggccctt cggtgacgcg ggcggcaccg gtgcggcggc
    14461 gacgctggcc gctgcggcgt cccgggcgat ggtctcgggc accaggcggc cgctgcggta
    14521 gccgatgccg atgccggcga ccagcacgaa gatcgcgccg aacgtctgga gcgagccgat
    14581 cagcgcgccg cccaggccga gcagcggggc ggcgatcatc agcatggtcc cgtcgccgta
    14641 ggagaacatc ccggaccggg cgacggacca gccggtcagg aaccagccca cgctgtagag
    14701 ggtggcgccg aacagcacga tgccccgcgc ggtcacgccg aacacgggcg tctgctcggc
    14761 caggccggcg aacgggagca tcagcaccat cccgccgatg ctgcacagca gcccggccag
    14821 cgcgatccgg cggcagcggg tggcggcgag caggccggtg agcgcgagca gggcgagcag
    14881 cccgagccac accgaggcga cccagccgac caggtagagc ggccggccgt cggccgggta
    14941 cgggtcgttg cccaccccgc cgtcgctggc catcgccacc aggccgtaga gcaccgcgta
    15001 cgccggcagc agccagaccg ccgcgcgggc gaaccggcgg accgaccagg cccaggtcgc
    15061 gtcggtggcc ggcgcgccgc ggccggactc ggagacgaac ggcaggaccc cgaaaccccc
    15121 tccggtacgc cgggagccga tcggcccggc ggggtcgtgc gcaccgggga ccggggtacg
    15181 ggagaacagc cggttcgccg ggtccttcat gcctcacctc gttcgcgccg cgggcggccc
    15241 gggacacgca acggcgctcc ggccctgctc accacccgtc ctgaaaccga tggtggcagc
    15301 cgccggagcg ccgcatgagg gattctcgga tttgccggtc agccccgctc gcgctggtcc
    15361 gccgggtcgt tcaccaggct ggccggtgac accggctccg gcgcgggcag accctgcggg
    15421 gtgttgccgc cggtggcctg cgcctccgcc acacgtacct cgtcgtggat ctcctgggcc
    15481 gcgatggccg cggcctgggc cgcctcggcg gcctcccgct cgacctcgcc ggcgctcttg
    15541 gcagcctccg gcgagggctg gtcgccgacc atgttggcca gcccgcccag cgcgccgccc
    15601 atgccctcca gggccttggt cagctcggtc gggacgatcc agaccttgtt ggccgtgccg
    15661 ttggcgatct gcggcagcgc ctggaggtac tggtaggcca gcaccttctg gctcgggttg
    15721 gcggtgtgga tcgcgtcgaa gacggtacgg atcgccttcg cctggccctc cgcctgcagg
    15781 atccgggcct gccggtcacc gtcggcgcgc agcaccgcgg cctgcttctc accctcggca
    15841 gtgaggatct gcgactgctt gtggccctcg gcgttgagga tcgcggcacg gcggtcccgc
    15901 tcggcgcgca tctgcttctc catggagtcg cggatgctcg gcggcggctc gatcgccttg
    15961 atctcgaccc gggtcacctt gatgccccag cggccggtgg tctcgtccag cacgccggac
    16021 aggtgccggt tgatctcctc gcggctggtc agcgcgcgct ccaggtccag cgagccgatc
    16081 acgttacgca gcgtggtgac ggtgagctgc tcgatcgcct ggaggaagtt ggagatctcg
    16141 taggtggcgc gaaccgagtc gaccaccttg aagtagagca ccgtgtcgat cgagacgacc
    16201 aggttgtcgg aggtgatcac cggctggggc gggaagctga ccacctgctc gcgcatgtcg
    16261 accttggtgc gcaccgcgtc cacgaacggc accagcaggt tgaggcccgg gttcagggtg
    16321 cgcttgtacc ggcccagccg ctccaccacg ccctgccgct gctgcggcac gatccgtacc
    16381 gccttgaaca gcgtcaccac accgatcaac gccaccgcga tcatcaggat cgccagaaac
    16441 tccataccgt tcaccttttc gcttcgggca gctcgcccgg gggagaaatg tcgtcctgcc
    16501 ataccagggc ggtagcgccc cggaccttga tcacctgcac ccgctcaccc tcggcgtacg
    16561 cgcgcgtcgc gtcgtacgag cgggccgtcc acagctcacc gtcaatcttg atcatgccgc
    16621 gctcggcatc gaccggctcc aggaccacag cggtggcccc ctccagcgcc tcgaccccga
    16681 acggctgctc cccggtctcg atcgccggcc gcgcgtgccg ccggaccacc ggccggacca
    16741 ccgccaccga caacgccgac accacggcga agatcaccgc ctgcagcgcc accggcgcac
    16801 cgagcgccgc ggcgccggca gcggcgaacg ctccgacccc gaacatgatc aggaagagcg
    16861 tcgtcgtgaa gatctcggcg accgctaata ccacacccag aacgatccag aacacggcgt
    16921 ccacgagaac aatcctgaca cgtcaacgca cgtgtcatcg aactgtcatg atcgctaggc
    16981 tcggctcggc gtaccgcgcc gcccgccgac gaggaggacg acatggccct gctgcccgaa
    17041 accgcgcgtc aggtggacct cctggtcgcc cgggcccagg ccgaagggcg gggcccgtcg
    17101 ctcgctctcg gcgtaatccg cgacgggcgc ctggcgcacc tggccgtcgc cggtgagacg
    17161 ccccgccccg acgccgacct ccagtaccgg atcggctcga tcaccaagac catgaccgcg
    17221 gtgctggtga tgcagcagcg cgacgccggc cggctggcgc tggacgaccc gctggacgcg
    17281 cacctgcccg gcaccccggt cgggtccgtg accgtgcgcc ggctcctcgg ccacgtcagc
    17341 gggctgcaac gcgagccgga cggccagtgg tgggagcgga ccgagggcgc ggacctgccg
    17401 acgctgctcg ccgggctgac accggacaag atcgcccacc cgccgcactt cgtctaccac
    17461 tactcgaacc tcgcgtacgg gctgctcggc ggcgtgctgg aacggatcac cggcaccccg
    17521 tgggcggagc tgctgaccga gcggctgttg gcgccgctgg gcatgcgccg caccacgtac
    17581 caccccaccg agccgtacgc ccccggctac gtcgtgcacc cctggcacga gacgctgcgg
    17641 gaggagccgc tcaccgacag cggggcgatg gcgcccgccg ggcagctctg gtcgacggtc
    17701 gaggacctgg gccgttgggc gtcgttcctg gccgacccgg acccggcgct gctctcgccc
    17761 gccacgctca ccgagatgtg cgcccccatg gtcatcaacg acctggactc gtggagcggc
    17821 ggccacggac tcggcattga gctctaccgg gtcggcgacc gggtgtacgt ggggcacggc
    17881 ggctcgatgc ccgggtacgt cgccggcctg gccgtccacc ggcccacccg caccgccgtg
    17941 gtgaacttcg ccaactcgta cggcctgcgc ggccaccaca tcggcgcgct cggccgggag
    18001 gcgctcacgc tggtgctgga cgccgaaccg gccgcgcccg ccccctggcg cccggccgac
    18061 ccgcccgccg ccgacgtggc cgcgctgacc ggccgctggt ggtggatggg cggcgagtac
    18121 gagttccgcg tcgacgccgc cggtgagctg gtcggcggtc aggtgggcag gccgcagctg
    18181 cgcttcaccc ccgagggccc ggaccggtgg cggggccgct ccggctccca ggacggcgag
    18241 atcctcaccg tgatccgcga cggttccggc accccggtag ccctcgacat agccaccttc
    18301 gtcctgaccc gaacccccga cgaactcccc taacccccgc cctcgccccc accctcgccc
    18361 ttcgcccccg cccccgcccc cgcctccgcc cccgccccgg cccgccccgg cccgccccgg
    18421 cgatcttgca cttacggccc ccatttcgcc ctgctatgcc cgacccgcgg gggccacaac
    18481 tccatgatcg acgcacaccc gcaccgccca cccccgtgat caaggagttt gcgtcggtgt
    18541 tgatctccaa tacacccaca aactccttga tcaacctggc gaggggcgcc aggaggggac
    18601 ccgaaaggaa gcccgagacg gggccggggc gggggacagg aggtccgagg gcgggcggag
    18661 ctgacgccac ggcgggtccg gcggcgggcg gagctggcgc ggcgggtcca ggggcgggcg
    18721 aagctgacgc ggcgggtcca ggggcgggcg gagctgacgc acggcggggc cgggggcgac
    18781 cgtgaccggc gcagggatca agcctgaccg cccggagccg ggcacgatcg cccccggccc
    18841 ccaaccgcaa ccacccagga ccgaaacaag tcagacaggc tcggtcacga agtcgatcaa
    18901 ccgctccatg gcgttgatca gcggcgtctc cacgtccgcg aaactgtcca cacgggacag
    18961 aatgcgccgc cacatgtcgg ccggctcggc caccccgagc gccgcgcaga cgccctcctt
    19021 ccagggctgt cccggcggca ccacaggcca cgccgcgatg cccagcgccg ccggacgtac
    19081 cgcctgccac acgtcgacgt aggggtggcc ggtgaccagc acgtgcggcg aggtgacccg
    19141 ggccacgatc cggctctcct tcgagccggg caccaggtgg tcgacgagca ccccgaggcg
    19201 gcggccgggg ccgggcgcga acgcgcgtac ctcctcggcg agcgcgtcaa tgccgtccaa
    19261 cggctccacc accacgccct cgatgcgcag gtcgtcgccc cagatccgct cgaccagcgc
    19321 ggcgtcgtgc acgccctcga cccagatccg gctggccttg gcgacctgcg cccgtacgcc
    19381 gtccaccgcg atcgacccgg acgcggtacg gcggcgcgcg gcgggcaccg gggcacgggc
    19441 cggccgccgt agcgtgaccg gccggccgtc gagcaggaac gcggcgggca gcagcgggaa
    19501 gttgcgccgc cgcccgtgcc ggtcctccag caccaccgcg ccggcgtcga agccgaccac
    19561 cgcgccgcag aacccggagt cggcgtcctc gaccaccagg tcgggttcgg cgtcgacttc
    19621 gggggtcacc ttccgtcgcc gccagtcgcc ggccagcacg tcgccgtcgt atcgccccgc
    19681 catgccggag acgctaacca cgacctcggc gtgtcgctcg ccgacgcgcc gaccgggccg
    19741 tcatccgtcg gcacgaaacg gtgcgaaggg gttagttggg ggcaggtcgc gccaccggag
    19801 cggcagccga gacagcagcg gcgcggagca cgtacccttt cggcatgtcc tcccccgcag
    19861 cgggcgcggc cacactggct ccgcgccggt cgagccggtt cgtcgcctgg gtgcgtgcct
    19921 ggcgagccgg cctggtgccg ttcgacgagg tggccgacgc ggttgccggc gacgaggagc
    19981 acctggtcgc cgacgcaccc ggcacctgga ccgacgtgtc cctgcgggag gcgctgccca
    20041 gcctggccaa gcactccccg gacgacatcc gcctggtgct gcccgcgccc ggcgacccgc
    20101 gcggcctgcc cggcccgggc gcgttcgccg gggcggcgct ggtggccggc gaggcggtgg
    20161 tggccagcgg gatggggttg gtgccggagg tccgcacgca cacctccggc tcggggatga
    20221 cctgggagac agtgctctgg cgggtccacc cgctgccggc ggacgcgccg aaggcgtccc
    20281 tgtccacgcc cggcgcggcg gaggccgagg cggaactctc cgctgtgctc gccgagacga
    20341 ccgccacgct gacccggctg gacgtcgcgc agtggcggcc cgagctggcc ggcgcgctcg
    20401 ccgcgctgcg ccgcccggac ggcgccaccg acctgccgcc gggcttcgac ccgcgggccc
    20461 gccggttgtt cgcgcgcgcc gccgtactcg atcgggtgct cgcgcttgcc ggggagagcg
    20521 cgcccggcgg cgcggtgaac acctacgagg cgcagcaacg ggacgcggcg ctgcggccgc
    20581 tgaccaccgc ctgccggcag gccctggtgg ccgcctgcaa cgcgccgctg cggctgtaga
    20641 acgccggctc agacctcgtc gatcaggtcg gccaccgagt cgacgatccg cgagggacgg
    20701 tacgggtacc gctcggcctc ggcccggctg ctgatgccgg tgagcaccag gatcgtctcc
    20761 aggccggcct ccagcccgca caggatgtcg gtgtccatcc ggtcgccgat catcgcggtc
    20821 gactcggagt gggcgtcgat ggtgttcagc gccgagcgca tcatcatcgg gttgggcttg
    20881 ccgacgaagt acgggtcgac gccggtcgcc ttggagatca tcgccgccac cgagccggcc
    20941 gccggcagcg cgccctccat cgacgggccc gtggcgtccg ggttggtgca gatgaaccgg
    21001 gcgccgtcgt tgatcagccg gatcgccttg gttatcgcct cgaagctgta ggtgcgcgtc
    21061 tcccccagca ccacgtagtc cggggcgaag tcgctgag
//
