LOCUS       NZ_CP030865            22607 bp    DNA     circular CON 14-AUG-2024
DEFINITION  Micromonospora sp. B006 chromosome, complete genome.
ACCESSION   NZ_CP030865
VERSION     NZ_CP030865.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sp. B006
  ORGANISM  Micromonospora sp. B006
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Complete Genome of Micromonospora sp. Strain B006 Reveals
            Biosynthetic Potential of a Lake Michigan Actinomycete
  JOURNAL   J Nat Prod 81 (9), 2057-2068 (2018)
   PUBMED   30110167
REFERENCE   2  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2018) Medicinal Chemistry and Pharmacognosy,
            University of Illinois at Chicago, 900 S Ashland Ave, Chicago, IL
            60607, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 77.6x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003408515.1-RS_2024_08_14
            Annotation Date                   :: 08/14/2024 03:31:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,342
            CDSs (total)                      :: 6,278
            Genes (coding)                    :: 6,199
            CDSs (with protein)               :: 6,199
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 20 of 79
            Pseudo Genes (incomplete)         :: 62 of 79
            Pseudo Genes (internal stop)      :: 6 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:07:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2336107
            Orig. end                         :: 2358714
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22607
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="6"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22607
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22607
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12607](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12607
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(645..770)
                     /locus_tag="MicB006_RS32600"
                     /old_locus_tag="MicB006_2242"
     CDS             complement(645..770)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MicB006_RS32600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MicB006_2242"
                     /product="hypothetical protein"
                     /protein_id="WP_255419521.1"
                     /transl_table=11
                     /translation="MNEHSGGGQLVRLVVSWLVVSALLGYGVVQTVITAAKLFTQ"
     gene            complement(767..2185)
                     /locus_tag="MicB006_RS11165"
                     /old_locus_tag="MicB006_2243"
     CDS             complement(767..2185)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1137: Major
                     facilitator superfamily MFS 1"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286346.1"
                     /locus_tag="MicB006_RS11165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2243"
                     /product="OFA family MFS transporter"
                     /protein_id="WP_116505773.1"
                     /transl_table=11
                     /translation="MLSALDRRHTVAPPGYSRWLIPPAALAIHLCIGQVYATSVYKNSL
                     IAHFDTSQTAIGVIFSIAIVMLGLSAAVAGTWVEANGPRKAMFVSACFWAAGFLVGALG
                     IATGQLWLLYLGYGVLGGIGLGIGYISPVSTLIKWFPDRPGLATGLAIMGFGGGAMVAS
                     PLSRQLLSFYDAGYDPSDSGSTASGSALVWLFVTLGIGYFVIMMFGVFNVRVPAPDWRP
                     AGFDPAQVAEKPLVTTANVSAANAVRTRSFWLLWVVLFCNVTAGIGILEQASPMIQDFF
                     REGGTSAVSVAAAGGFVGLLSLFNMAGRFVWSSTSDVIGRKPIYVVYLGVGMVLYLVLA
                     LVGQTSTALFVLLASVILSFYGGGFATIPAYLRDLFGTFEVGAIHGRLLTAWSAAGVAG
                     PLIVNGFLDAQGEPGTLTAAAYRPALFTMVGVLAVGLVANLLVRPVPERYHEPASGRGE
                     TEQGQPGSTERSGS"
     gene            2366..3217
                     /gene="pdxY"
                     /locus_tag="MicB006_RS11170"
                     /old_locus_tag="MicB006_2244"
     CDS             2366..3217
                     /EC_number="2.7.1.35"
                     /GO_function="GO:0008478 - pyridoxal kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009443 - pyridoxal 5'-phosphate salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pdxY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019872348.1"
                     /locus_tag="MicB006_RS11170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2244"
                     /product="pyridoxal kinase PdxY"
                     /protein_id="WP_116505775.1"
                     /transl_table=11
                     /translation="MKILSIQSSVAYGHVGNSAAVFPLQRLRHEVWPVLTVHFSNHTGY
                     GAWRGPLLAPTDVADVIAGIEDRGVLGTADAVLSGYQGDPAVGAVILDAVARVKAANPA
                     ALYCCDPVMGDVGRGMFVRPGIPEYLRDTVVPRADIVTPNQFELEFLAGRTTDTLDDLL
                     AAVDTVRAAGPRHVLVTSVLHGDLPAGHLEVVAVSDDGAWAVTTPLLPIAPNGGGDVTA
                     ALYLAHLVTTGSPQTALEHTTNSIYAVLEATLEAGTRELQIVAAQDAIAQPPTRFTARR
                     LR"
     misc_feature    2367..2381
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.46"
                     /tool="antismash"
     gene            3315..3779
                     /locus_tag="MicB006_RS11175"
                     /old_locus_tag="MicB006_2245"
     CDS             3315..3779
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286348.1"
                     /locus_tag="MicB006_RS11175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2245"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_116505777.1"
                     /transl_table=11
                     /translation="MSPHQGTDDPAFAQRLRDLTRLRRVRDRIDREYARPLDVEALARG
                     EHMSAGHLSRQFRLTYGESPYAYLMTRRIERAMALLRRGDLSVTDVCFAVGCQSLGTFS
                     TRFTELVGEPPSAYRARHAPDTAEPPPCLTKQATRPVRNREARTARPPLA"
     gene            3785..4195
                     /locus_tag="MicB006_RS11180"
                     /old_locus_tag="MicB006_2246"
     CDS             3785..4195
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574739.1"
                     /locus_tag="MicB006_RS11180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2246"
                     /product="VOC family protein"
                     /protein_id="WP_030503949.1"
                     /transl_table=11
                     /translation="MTITIHYTFLPHTDADAALAFYRDTLGFELRNDVGYQDMRWLTVG
                     PPNQPETGIVLHPPAADPGITDDERRTILELIAKGSYGALTLATDDLDGLFDRLQASGA
                     DVVQEPTEQPYGVRDCAFRDPTGNLIRINERR"
     gene            4204..4653
                     /locus_tag="MicB006_RS11185"
                     /old_locus_tag="MicB006_2247"
     CDS             4204..4653
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286350.1"
                     /locus_tag="MicB006_RS11185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2247"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_116505779.1"
                     /transl_table=11
                     /translation="MADAPRTRAQRRHDTTHRLDHDVDCWVATAGPDGTPYLVPLSFDW
                     DGHTLLVATPADSPTGRNLAGGRARIGLGPTRDVTMIDGDVESLAIDALPTARADRFAT
                     RTGFDPRTLTTSYRWYRLTPRRVQAWREADELPGRTLMRDGRWLD"
     gene            4682..7057
                     /locus_tag="MicB006_RS11190"
                     /old_locus_tag="MicB006_2248"
     CDS             4682..7057
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012182622.1"
                     /locus_tag="MicB006_RS11190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2248"
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_116505781.1"
                     /transl_table=11
                     /translation="MSEATAGLHRADSHDVIRVLGARENNLRHVDVELPKRRLTVFTGV
                     SGSGKSSLVFGTIAAESQRLINETYSAFVQGFMPTLSRPEVDVLEGLTTAIIVDQERMG
                     ADPRSTVGTATDVNAMLRILFSRLGDPHIGPPNAYSFNVPSVRAAGAITVERGPGKTQT
                     KKGTFNRLGGMCPRCEGRGAVTDFDLTVLYDEKLSLNEGAITIPGYSMDGWYGRIFRSS
                     GLFDPDKPIRDYTKRELSDLLHKEPTKIKVDGINVTYTGLIPAIQKSMLAKDVDAMQPH
                     IRAFVERAITFTTCPDCDGTRLSPEARSSKINGISIADACAMQISDLATWVRDLREPSV
                     GPLLTALGDTLDSFVEIGLGYLSLDRPAGTLSGGEAQRTKMIRHLGSSLTDVTYVFDEP
                     TIGLHPHDIARMNNLLLQLRDKGNTVLVVEHKPETIAIADHVVDLGPGAGTAGGTICYE
                     GTVAGLRASDTTTGRHLDDRATCKDKLRTPTGALPIRGARTHNLRDVDVDIPLGVLVVV
                     TGVAGSGKSSLIHGSLAKREDVVSVDQTAIRGSRRSNPATYTGLLDPIRKAFAKANGVK
                     PALFSANSEGACPTCNGAGVIYTDLGMMAGVASTCEDCEGKRFQPAVLDYHLGGRDISE
                     VLAMSVDEAETFFSNGEARTPAAHTILDRLADVGLGYLTLGQPLTTLSGGERQRLKLAT
                     RMGDKGGVYVLDEPTTGLHLADVAQLLGLLDRLVDAGKSVIVIEHHQAVMAHADWIIDL
                     GPGAGHDGGRIVYEGTPADLVAARSTLTGEHLADYVGA"
     gene            complement(7073..7780)
                     /locus_tag="MicB006_RS11195"
                     /old_locus_tag="MicB006_2249"
     CDS             complement(7073..7780)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018784313.1"
                     /locus_tag="MicB006_RS11195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2249"
                     /product="response regulator transcription factor"
                     /protein_id="WP_073829980.1"
                     /transl_table=11
                     /translation="MIRVLLADDQPLVRAGLAMLLTNEPDIEVVAEADDGAQAVEVSRR
                     LRPDVVLMDVRMPGTDGLAATRLMADEQLIDDPQRPVRIIMLTTYHVDEAVHAALRAGA
                     SGFVLKDAAPAELVSAIRAVAAGEAWLDPAVARRLLDDLAARPDPGLPTPVQMRGLTPR
                     EREVLVLMAYGMSNREIAEHLVLGDATVKTHVSRVLTKLGMRDRTHAVVAAYQCGLVEP
                     GTAPPARMAGLSR"
     misc_feature    complement(7804..7816)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            complement(7879..9138)
                     /locus_tag="MicB006_RS11200"
                     /old_locus_tag="MicB006_2250"
     CDS             complement(7879..9138)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="MicB006_RS11200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2250"
                     /product="sensor histidine kinase"
                     /protein_id="WP_116505783.1"
                     /transl_table=11
                     /translation="MTSVTGAVAPSAPARAASWWRHDLLLLPVLGLLDLFTASSVVIQS
                     EPVGPARQWLQVLAAVLSVGALWWRARAPVAVFAFECVHGAAMWFLLHDYRPWVGLIVA
                     LYTVAALRPLVVSAAAYTAACARSLLSAFDSFRVEPSPGARAGEFVVTALMFALIYAAA
                     WTAGSVVRRHRRRVAQLERERRVARAEAVALERRRIAAELHDVVSHSVTVMVLQAAGAA
                     RISASDPERTREALLHIQQAGQQAMAELRRLLAVMRAESGPAVDGEPGPQPRLDDIEVL
                     LTSMRCAGLTVTMSVSGSARPLDPSIELAAYRTVQESLTNTLKHVGRRACATVHFGWQE
                     RVLLLRVDDDGTGRDPGAAAGLSTGNGLASLAERLERVGGRLVAGPRPEGGFRVSATLP
                     VAQRGDLVAASGDGGAPAVG"
     gene            complement(9146..9715)
                     /locus_tag="MicB006_RS11205"
                     /old_locus_tag="MicB006_2251"
     CDS             complement(9146..9715)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MicB006_RS11205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MicB006_2251"
                     /product="hypothetical protein"
                     /protein_id="WP_116505785.1"
                     /transl_table=11
                     /translation="MRTEVQSPPMVVFLQAQRPAGWVTVARGVPLDGRRCLLRTVGAGR
                     ARSGDAVRLVGVAGGDARSLTVAEVSVLHRDEADLLMVSLAGATVPGGYGTDASAVRRV
                     LAMLADDADGRWRVAADAAADVVATVVLAGAGRAGEPGRPAVPVTTHRVSAATPPPDGD
                     GGGDDDGSPLSWTCRLFGIGCPAEDS"
     gene            10001..12607
                     /gene="lanKC"
                     /locus_tag="MicB006_RS11210"
                     /old_locus_tag="MicB006_2252"
     CDS             10001..12607
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="MicB006_RS11210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2252"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_116505787.1"
                     /sec_met_domain="micKC (E-value: 3.3e-243, bitscore: 808.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 2.5e-12, bitscore: 45.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.9e-15, bitscore:
                     53.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTPGAFLIADPVHVDSPAYVADAASRFPLADQTPPDGWRVAEHG
                     GWVMWHPPHAQLPQQGWKVHVSVNLDDAADALDLVREHCVRHRIAFKFQRSRRLALVNN
                     EKYAHRAGSGKLAALYPADDTALRRILDDLGAQLAGYRGPYVLSDLRWHDGPLYLRYGG
                     FAELWCVDGDHPVPAVTRPDGTLVPDRREPVFTVPDWAPVPDFVAEHIAAVDAQTDDEP
                     PYRIEEALHHSNAGGVYRATDLRDGRTVVLREARPHAGLDGAGTDALTRLRREEDMLRR
                     LAGLDCVPQLLDRLTWWEHQFLVEEHIEGDTLQHHLAMRHPLIHPDPTHQDLTDYTTWA
                     LHVIDQVEAALAQVHARGVVFGDLHTANVMIRPDGRVVLVDFEQAYLTDEDFTPSLGDP
                     GFATPRIRRGPAVDTYALACLRLAVFVPLTPLAALCDEKFDDLLTVARRFPLPPGYLDR
                     IRDDLHTALNPPAPDRRRVTRYPWPADQRRLIESLAAGIRATATPHRTDRLFPGDPGQF
                     PHGGATLAHGAAGVIWALVNTGVDYPERDEHLDWLTRAARRLPTAHLGLYDGLAGIAAL
                     LDRTGRHDDAGELLDRCRTGLHHRYGPGLHSGLAGIGLALLRPGRPAPDDALHIGDRLA
                     RTLAGDTKQPVPEPARPGLLHGWSGPAIFLTRLHEATGDPAWLRAARTALRRDLQHTVR
                     DDNGNLHVRDGARRLFYLDEGSAGIAVAAHTLLRHGERQWLRDVVTTVRRTIDVEFVLL
                     PGLFHGRAGLLATAALLTDDPPRGTTPHGPVGLVRDDAPHHVPAHLARLAWHAYALDGR
                     LAFPGDTLLRISTDLAAGGAGILSAIHAALHRTAVTLPFLDAPTHVAPTGHLLAAS"
     gene            12943..14214
                     /locus_tag="MicB006_RS11215"
                     /old_locus_tag="MicB006_2254"
     CDS             12943..14214
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF017760.4"
                     /locus_tag="MicB006_RS11215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2254"
                     /product="MFS transporter"
                     /protein_id="WP_116505789.1"
                     /transl_table=11
                     /translation="MPPTGLRHNRDFLLITVARTASKLGTQVTAVATPLLVLLTTGSAT
                     DAGLVAFAEGIALVLVLLPAGLLADRRDRRILMLCCDGGALLAVAGVTVLALVGHAPVL
                     LIAVLAAATAGLGAALQPAAAAATRAVVPARDLRTATVFNETRNGVVHLAGPPLGGFLF
                     GLAPALPFLVDAISYAVSLVAVALLRGPLGRSLTTPGESLPQQAVAGVRFLWRQPSLRF
                     TLLCGAVLNFAFAGVLLAIIVVPVRNGASGLSAGTVMACVGLGAVAGSLVASWLTARVP
                     TRWLILAVVWACAVLTAAMATTDNGLILGALAGACVLVVPAANISMLTLQTLLTPGDLQ
                     GRANAATSFIALIVAPFGPALSGLLIDRVPAPVVFGSFAAVMLTLAVGAAVAPAVRAMP
                     DLRAVEDVAEPEPGEAERRDPQPV"
     gene            14350..15090
                     /locus_tag="MicB006_RS11220"
                     /old_locus_tag="MicB006_2255"
     CDS             14350..15090
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="MicB006_RS11220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="MicB006_2255"
                     /product="hypothetical protein"
                     /protein_id="WP_116505790.1"
                     /transl_table=11
                     /translation="MDLRRSRQTLWKGLTVFGVGVFPLLYLTSASTGRWIVLGLWLVSA
                     GVFVAYQLRPFRFRIGADGLDLRVAGLNRLVAWAEIDAVVLDQPLPSGGRKQRAASVLL
                     VPATASTIDRRLTGRSPVDGRPALVLLDLDQVQQPADEVAAALARFGASRFADVRQRAP
                     ERSDDPGAPDMEALTLLADLTPRVQKALDSGQASQRQAVKAEVDAALARLREAPAGSDQ
                     PRLAALLKVMSETLGEEGEGVKAS"
     misc_feature    complement(15122..15138)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.49"
                     /tool="antismash"
     misc_feature    complement(15653..15668)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.89"
                     /tool="antismash"
     gene            15676..16674
                     /locus_tag="MicB006_RS11225"
                     /old_locus_tag="MicB006_2256"
     CDS             15676..16674
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476777.1"
                     /locus_tag="MicB006_RS11225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2256"
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_116505792.1"
                     /transl_table=11
                     /translation="MHDKPDETVGVLIEEFLTARATRKPSPHTLAAYRRDLTTVAELVA
                     ADGDTTPLPLDRLAVGSLSPRVMRAAFARFAAPRAAASVHRAWSTWNSFFTFLVAEGVV
                     PGNPMPAVGRPRTPLPRPKPLRGEDTPEELLAAVARAEGRQRDPWPERDLAVLALALCA
                     GLRLSELLALRVSSVAGRDGERRVDVAGKGGRPRTVPIEDAVDRVLAGYLDSRRYRFGS
                     RSVRPDAPFLVDRQGEALRRGGLQYLVESCYRRAGIGDRVPRGARLHALRHTFATRLAE
                     DGASASEIMRLLGHASLASSQTYIEVTAGQQRAAVAANRTNRALSGLTPRR"
     gene            16715..17734
                     /locus_tag="MicB006_RS11230"
                     /old_locus_tag="MicB006_2257"
     CDS             16715..17734
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013286355.1"
                     /locus_tag="MicB006_RS11230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2257"
                     /product="hypothetical protein"
                     /protein_id="WP_116505794.1"
                     /transl_table=11
                     /translation="MRVGAARAVAVGWVRERMRVDPSIEGAFFSGSTVGLPDDAVLPPW
                     SDVDVLLVRWNPGVKVGKFVHRGVLLEVSTVTWEELGGPEDVLGSWVFAPMFRTDGVIA
                     DPSGRLAAVRERVAAGFADPVWVRARCAGVRRRIEAGLRAVGGSAPVAEQVLAWVFPTS
                     LLAVWPAVAGLADPTVRRRYVRAERVLSRFGFADRYPELLDTFDGGGVGVDAARVRAHL
                     AGLAVVFDEVSRLPREGFAFGADLGAAGRPVVFDGAAELIAAGRHREAMFWVLVTYARC
                     HVVLGAVAPERERAFGAVLADLGVASAADRRRRADALLAALPGWQSVVDAVAAEAVAG"
     gene            17828..18694
                     /locus_tag="MicB006_RS11235"
                     /old_locus_tag="MicB006_2258"
     CDS             17828..18694
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476775.1"
                     /locus_tag="MicB006_RS11235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2258"
                     /product="bifunctional 5,10-methylenetetrahydrofolate
                     dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="WP_116505796.1"
                     /transl_table=11
                     /translation="MSSARLLPGAPVAERVLSEVAASVAELRAAGVTPALATVLVGDDD
                     ASAGYIRIKQRQAAELGFVSPHVHLPASASQADLHAVLADFNADKTVHGVLVQYPIPGR
                     LDYDRALAELDPDKDVDGMHPVNMGRLALGLPGPLPCTPAGIEALLAFHGVPVAGREVV
                     ILGRGATLGRPLAMLLAQKRPTANAAVTVVHTGVADWPRYTRRAEILVAAAGVPGIVRP
                     EHVRPGAVVVGGGVRYEGRRLLPDVDESCAEVAGAITPRVGGVGPTTVAMLFRNAVEAA
                     RRQSGLG"
     gene            complement(18698..19477)
                     /locus_tag="MicB006_RS11240"
                     /old_locus_tag="MicB006_2259"
     CDS             complement(18698..19477)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018813262.1"
                     /locus_tag="MicB006_RS11240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2259"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_116505798.1"
                     /transl_table=11
                     /translation="MRLATFNLLHGRSLTDGLVDPDRLTAAVTALDADVLALQEVDCDQ
                     SRSGKLDLTALAARALHADHHRFAAAVVGTPGEQFRPLTHDDDGHGEPLYGIGLISRHP
                     VRSWQVTRLRAAPVRSPIYAPGPGGGLILLRDEPRVVLAAVLDTPHGPLTVAATHLSFV
                     PGWNVWQLRRVVRALRTLPAPRILLGDLNLPAGPAAALTRWRPLARRPTYPAGQPRVQL
                     DHILADRHALDRLPPVTAVHTPLATISDHRPLVVDLG"
     gene            19652..20422
                     /locus_tag="MicB006_RS11245"
                     /old_locus_tag="MicB006_2260"
     CDS             19652..20422
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460321.1"
                     /locus_tag="MicB006_RS11245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2260"
                     /product="TSUP family transporter"
                     /protein_id="WP_073829466.1"
                     /transl_table=11
                     /translation="MDALSLTTLLTAALVAGWVDAVVGGGGLLLLPALLVAAPGVPVAT
                     ALGTNKLAAIFGTSTAAVTYARRTKLDWAVAGPAAGLAVVTAGLGAALAGAVPGSAYRP
                     VVLVVLVAVAVFVLARPSLGVVSSPRRTPRRVVVAVAVAGLGIALYDGLIGPGTGTFLV
                     LAFTAILGSDFVHASAMAKVVNAGTNLGALVVFGLTGHVWWALGAAMAVCNVVGAAVGA
                     RMALRRGAGFVRVVLLVVVLALVVRLGYDQWVAG"
     gene            20407..21210
                     /locus_tag="MicB006_RS11250"
                     /old_locus_tag="MicB006_2261"
     CDS             20407..21210
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476772.1"
                     /locus_tag="MicB006_RS11250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2261"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_116505800.1"
                     /transl_table=11
                     /translation="MGGGLIAVAVRAEHDRAVLAGLLGRDPVLHAYQLGDLDDFFWPYT
                     SWFRRGDQVVLLYHGVELPTLLAFAAPDRVAELAGLLAEAAPVLPARMWAHLSPGLEAT
                     LGRWFVVSEAAAHHRMALTDPGRLAAVPAVGEPLGPADAAELAGLYAVAYPGNWFDARM
                     LETGQYVGVRERGRLVAVAGVHVFSPRWRVAALGNVTTHPDVRGRGLGAGVVAALCARL
                     LTSVDHVTLNVQADNAAAVRLYERLGFSRVAGFTECALTSAAAAG"
     gene            complement(21190..21699)
                     /gene="def"
                     /locus_tag="MicB006_RS11255"
                     /old_locus_tag="MicB006_2262"
     CDS             complement(21190..21699)
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018805352.1"
                     /locus_tag="MicB006_RS11255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2262"
                     /product="peptide deformylase"
                     /protein_id="WP_116505802.1"
                     /transl_table=11
                     /translation="MTMRPIRIIGDPVLRTPSEPVTSFDAELRALVEDLMDTLLGAPGR
                     AGVAAPQIGVNAQVFVYDADGHRGHMVNPTLDVSDELQDDDEGCLSIPGLYFPTPRALH
                     ATAHGYDQHGEPLTITGSGFLARALQHETDHLRGRLYVDTLRGDTRRRALREIRAGRFD
                     SPSRGR"
     gene            complement(21721..22218)
                     /locus_tag="MicB006_RS11260"
                     /old_locus_tag="MicB006_2263"
     CDS             complement(21721..22218)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024212.4"
                     /locus_tag="MicB006_RS11260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_2263"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_116511358.1"
                     /transl_table=11
                     /translation="MTAPDRDALGTLLRHVLDVLDGDVAAVHHRLGLTDYRPRYSPVVR
                     ALVADGPLPIRDLATRVGVTHSAASQTIAQMRRAGLVDLRPGADARHRIVTLTDRARAL
                     LPAVEAEWAATTTAMRHLDTELPVPLADELYAVLDALRRRPLRDRIADTGVLDTPPDTA
                     DR"
     misc_feature    22227..22244
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.19"
                     /tool="antismash"
     misc_feature    complement(22505..22520)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.62"
                     /tool="antismash"
ORIGIN
        1 cgacgtgcgc gccgccggcc gccgcgcggt caccgtcgcc gccgacacca ccgaccccga
       61 ccaggtacgc cggatcttcg acgccgccga ccagctcggc ccgctcaccg gcctggtcaa
      121 caacgccggc gtcaccagcc cgatcggccc gttcaccgac ctgcgcgtcg acgacctgcg
      181 cgaggtcgtc gacgtcaacc tcatcgggta cgtgctctgc gcccagcagg cggcccgtcg
      241 gctcacccac ggcggcgcca tcgtcaacgt ctcctccgtg gcagccacgc tcggctcacc
      301 cggcgagtac gtccactacg ccgccgtcaa ggccgccacc gacaccctca ccgtcgggct
      361 ggcgaaggaa ctcgcgccgc gcggcatccg ggtcaacgcc gtcgctccgg gcatcatccg
      421 caccaccatc cacgcccgct ccggcgcgcc cgaccggccc gacaccgccg ccggacggat
      481 cccgctgggc cgcgccgggg aacccgagga ggtcgccggc gcgatcgccc acctgctcgg
      541 cccggacgcc tcgtacacca ccggcgcggt cctgcgcgtc ggcggcgggc tctgacacga
      601 cggcggcccg ggggtcccgc ccccgggccg ccgcgtcgcg tctcctactg ggtgaacagc
      661 ttcgccgccg tgatcaccgt ctgcaccacg ccgtagccca gcagcgccga caccaccagc
      721 cacgacacca ccaggcgaac cagctgcccg ccaccgctgt gctcgttcac gatccgctcc
      781 tctccgtcga ccccggctgt ccctgctccg tctcgccccg cccggacgcg ggctcgtggt
      841 agcgctccgg caccggccgc accagcaggt tcgccaccag gcccaccgcc agcacgccga
      901 ccatcgtgaa cagcgccggc cggtacgccg ccgcggtcaa cgtgcccggc tcgccctgcg
      961 cgtcgaggaa cccgttgacg atcagcggcc cggccacgcc cgccgccgac cacgcggtca
     1021 gcagccggcc gtggatcgcg cccacctcga acgtgccgaa caggtcccgc aggtacgccg
     1081 gaatggtcgc gaacccgccg ccgtagaacg acaggatcac ggacgccagc agcacgaaca
     1141 acgccgtcga ggtctgcccc accagcgcca gcaccaggta cagcaccatg cccacaccca
     1201 ggtacaccac gtagatcggc ttacggccga tcacatccga cgtggacgac cacacgaacc
     1261 ggcccgccat gttgaacagc gacagcagcc ccacgaatcc gccggccgcc gccaccgaca
     1321 ccgccgacgt gccgccctcg cggaagaagt cctggatcat cggactggcc tgctccagga
     1381 tgccgatgcc cgccgtcacg ttgcagaaca gcaccaccca cagcagccag aacgaccgcg
     1441 tcctgaccgc gttggccgcc gacacgttgg cggtggtcac cagcggcttc tcggccacct
     1501 gggccggatc gaacccggcc gggcgccagt ccggcgcggg cacccgcacg ttgaacaccc
     1561 cgaacatcat gatcacgaag tagccgatgc cgagcgtcac gaacagccac accagcgccg
     1621 acccggacgc cgtggaaccg ctgtccgacg ggtcgtatcc ggcgtcgtag aacgacagca
     1681 gctgtcggga caggggagag gccaccatcg ccccgccacc gaaccccatg atcgccagcc
     1741 cggtcgccag acccggccgg tccgggaacc acttgatcaa cgtggagacg ggggagatgt
     1801 agccgattcc cagaccgatg ccgcccagca cgccgtaccc cagatacagc agccacagct
     1861 gcccggtcgc gatgcccagc gcaccgacga ggaaacccgc cgcccagaaa cacgccgaga
     1921 cgaacatcgc cttacgcggc ccgttcgcct ccacccacgt accggccacc gcggccgaca
     1981 gccccagcat cacgatcgcg atgctgaaga tcaccccgat cgccgtctga ctcgtgtcga
     2041 aatgcgcgat cagggagttc ttgtacacgc tcgtcgcgta cacctgcccg atgcacagat
     2101 ggatcgccag cgccgccgga gggatcagcc agcggctgta ccccggcggc gcgacggtgt
     2161 gccgacgatc gagtgcggaa agcatcgttg cttcctccgt ccagatggcg agaacacagg
     2221 cggttcatgc ccccaccgca cgctgcgccc aaacccgctc cgcgccgggc ggtcgaaacg
     2281 ctgagccgaa cggtcaccgc cgcagccacc cgtcatcacg ccaccaccgc ccgtcacacc
     2341 cgccccggga tgcgaccatg agcaggtgaa gatcctgtcc atccagtcgt cggtcgccta
     2401 cggccacgtc ggcaactccg ccgccgtgtt cccattgcaa cgcctccgac acgaggtctg
     2461 gccggttttg accgtgcact tctccaacca caccggctac ggcgcctggc gcggcccgct
     2521 gctcgccccc accgacgtcg ccgacgtcat cgccgggatc gaggaccgcg gcgtgctcgg
     2581 caccgccgac gcggtcctct ccggctacca gggcgacccg gccgtcggcg cggtcatcct
     2641 cgacgcggtc gcccgggtca aggccgccaa cccggccgcg ctctactgct gcgacccggt
     2701 catgggcgac gtcggccgcg gcatgttcgt ccgccccggc atccccgaat acctgcgcga
     2761 caccgtcgtg ccccgcgccg acatcgtcac ccccaaccag ttcgagctgg agttcctcgc
     2821 cggccgcacc accgacaccc tcgacgacct gctcgccgcc gtcgacaccg tccgcgccgc
     2881 cggcccacgg cacgtcctgg tcaccagcgt cctgcacggc gacctgcccg ccgggcacct
     2941 ggaagtcgtc gccgtctccg acgacggcgc ctgggccgtc accaccccgc tgctgccgat
     3001 cgcccccaac ggcggcggcg acgtcaccgc cgccctgtac ctggcgcacc tcgtcaccac
     3061 cggctcgccg cagaccgcgc tggaacacac caccaactcg atctacgcgg tactcgaggc
     3121 gaccctcgaa gccggcaccc gggagctgca gatcgtcgcc gcccaggacg ccatcgcgca
     3181 gccgccgacc cggttcaccg cccgccggct gcgctgaccg tcgcccgggt gcacctgccg
     3241 cgcgggtgca cccggcgacg actcgccgcc cgaactggtg gacgacacca ccgcccagca
     3301 ggcaggatgc ggacgtgtca ccgcaccagg gcaccgacga ccccgcgttc gcccagcgcc
     3361 tgcgcgacct gacccggctc cgccgcgtcc gcgaccgcat cgaccgcgag tacgccagac
     3421 ccctcgacgt cgaagccctc gcccgcggcg agcacatgtc cgccggccac ctcagccgcc
     3481 agttccgcct gacctacggc gaatccccgt acgcgtacct catgacccgc cgcatcgaac
     3541 gcgcgatggc cctgctgcgc cgcggcgacc tcagcgtcac cgatgtctgt ttcgccgtcg
     3601 gctgtcagtc cctgggcacc ttcagcaccc ggttcaccga actcgtcggc gagccgccca
     3661 gcgcctaccg tgcccgccac gcccccgaca ccgccgagcc gcctccgtgc ctgaccaaac
     3721 aggcgacccg accggtcagg aatcgagaag cccgcaccgc ccggccacca ctagcgtgac
     3781 caccatgacg atcaccattc actacacgtt cctgccgcac accgacgccg acgccgctct
     3841 cgccttctac cgcgacaccc tcggcttcga actgcgcaac gacgtcggct accaggacat
     3901 gcgctggctc accgtcggcc caccgaacca gcccgagacc ggcatcgtcc tgcacccgcc
     3961 ggccgccgac cccggcatca ccgacgacga acgccgcacc atcctcgaac tcatcgccaa
     4021 gggcagctac ggcgcgctca ccctcgccac cgacgacctc gacggcctgt tcgaccgcct
     4081 ccaggccagc ggcgccgacg tcgtccagga gcccaccgaa cagccctacg gcgtacgcga
     4141 ctgcgccttc cgcgacccca ccggcaacct catccgcatc aacgagcggc gctgaccccg
     4201 cccatggccg acgcgccccg cacccgcgcc cagcgccgcc acgacaccac ccaccgcctc
     4261 gaccacgacg tcgactgctg ggtcgccacc gccggccccg acggcacccc gtacctcgtg
     4321 ccgctgtcct tcgactggga cggccacacg ctgctcgtcg ccacgccggc cgacagcccc
     4381 accggccgca acctcgccgg cggccgcgcc cgcatcggcc tcggccccac ccgcgacgtc
     4441 accatgatcg atggcgacgt ggaaagcctc gccatcgacg ccctgccgac cgcccgagcc
     4501 gaccgcttcg ccacccgcac cggcttcgac ccccgtacgc tgaccacttc ctaccgctgg
     4561 taccgcctca cgccacgccg cgtccaggcc tggcgggagg ccgacgagct gcccggccgc
     4621 acgctgatgc gcgacggacg ctggctcgac tagagcacca cccgacccgg acggagagac
     4681 catgagcgag gccaccgccg gcctgcaccg cgccgacagc cacgacgtca tccgcgtcct
     4741 cggcgcccgc gagaacaacc tgcgccacgt cgacgtcgaa ctgcccaaac gccgcctcac
     4801 cgtcttcaca ggcgtctccg gctccggcaa gagctcactg gtcttcggca ccatcgccgc
     4861 cgagtcgcag cgcctgatca acgagaccta cagcgccttc gtccagggct tcatgcccac
     4921 cctgtcccgg cccgaggtcg acgtcctgga gggcctcacc accgccatca tcgtcgacca
     4981 ggaacgcatg ggcgccgacc cgcgctccac agtcggcacc gccaccgacg tcaacgcgat
     5041 gctgcgcatc ctgttcagcc gtctcggcga cccccacatc ggcccgccca acgcgtactc
     5101 gttcaacgtc ccctccgtac gcgcggccgg cgccatcacc gtcgagcgcg gccccggcaa
     5161 gacccagacc aagaagggta ccttcaaccg cctcggcggc atgtgccccc gctgcgaggg
     5221 acgcggcgcg gtcaccgact tcgacctgac cgtcctctac gacgagaagc tgtccctcaa
     5281 cgagggcgcc atcaccatcc ccggctacag catggacggc tggtacggcc gcatcttccg
     5341 ctccagcgga ctgttcgacc cggacaagcc gatccgcgac tacaccaagc gcgagctgag
     5401 cgacctgctc cacaaggaac ccaccaagat caaggtcgac ggcatcaacg tcacctacac
     5461 cggcctcatc ccggccatcc agaagtcgat gctcgccaag gacgtcgacg ccatgcagcc
     5521 gcacatccgc gccttcgtcg aacgcgccat cacgttcacc acctgccccg actgcgacgg
     5581 cacccgcctg agccccgagg cccgctcctc gaagatcaac ggcatcagca tcgccgacgc
     5641 ctgcgccatg cagatcagcg acctcgccac ctgggtacgc gacctgcgcg aaccctccgt
     5701 cggcccgctg ctcaccgcgc tgggggacac cctcgactcg ttcgtcgaga tcggcctggg
     5761 ctacctgagc ctcgaccggc ccgccggcac cctctccggc ggcgaggccc agcgcaccaa
     5821 gatgatccgc cacctcggct cgtccctcac cgacgtcacc tacgtcttcg acgaacccac
     5881 catcggcctg cacccgcacg acatcgcccg catgaacaac ctcctgctgc aactgcgcga
     5941 caagggcaac accgtcctcg tcgtcgaaca caaacccgag accatcgcca tcgccgacca
     6001 cgtcgtcgac ctcggccccg gcgccggcac cgccggcggc accatctgtt acgagggcac
     6061 cgtcgccggc ctgcgcgcca gcgacaccac caccggccgc cacctcgacg accgcgccac
     6121 ctgcaaggac aagctgcgta cgcccaccgg cgcgctgccg atccgcggcg cccgcaccca
     6181 caacctgcgc gacgtcgacg tggacatccc cctcggtgtc ctggtcgtgg tcaccggcgt
     6241 cgccggctcc ggcaagagca gcctcatcca cggctcactg gccaaacgcg aggacgtcgt
     6301 cagcgtcgac cagaccgcca tccgtggctc ccgccgcagc aacccggcca cctacaccgg
     6361 cctgctcgac cccatccgca aggcgttcgc caaggccaac ggcgtcaaac ccgccctgtt
     6421 cagcgccaac tccgaaggcg cctgcccgac ctgcaacggc gccggcgtca tctacaccga
     6481 cctgggcatg atggccggcg tcgccagcac ctgcgaggac tgcgaaggca agcggttcca
     6541 gcccgccgtg ctcgactacc acctcggcgg acgcgacatc agcgaggtcc tcgccatgtc
     6601 cgtcgacgag gccgagacgt tcttcagcaa cggtgaggcc cgcaccccgg ccgcccacac
     6661 catcctcgac cggctcgccg acgtcggcct cggctacctc acgctcggtc agccgctgac
     6721 cacgctgtcc ggcggggaac ggcagcggct caagctcgcc acccggatgg gggacaaggg
     6781 cggcgtgtac gtcctcgacg agcccaccac cggcctgcac ctggccgacg tcgcccaact
     6841 gctcggcctg ctcgaccggc tcgtcgacgc gggcaagtcc gtcatcgtga tcgagcacca
     6901 ccaggcggtc atggcacacg ccgactggat catcgacctc gggccgggcg ccggtcacga
     6961 cggcggacga atcgtctacg aaggcacccc ggccgacctg gtggccgccc ggtccacgct
     7021 caccggcgaa cacctcgccg actacgtcgg cgcgtgagcg ccacaccgga cctcagcggg
     7081 acaggccggc catccgggcc ggcggcgccg tgccgggctc caccaggccg cactggtacg
     7141 cggccaccac cgcgtgcgtc cggtcccgca tccccagctt cgtcaggacc cggctgacgt
     7201 gggtcttgac cgtcgcgtcg ccgagcacga gatgctcggc gatctcccgg ttcgacatcc
     7261 cgtacgccat cagcaccagc acctcccgtt cccgcggagt gagcccgcgc atctgcaccg
     7321 gagtgggcag tcccgggtcg ggccgggcgg cgaggtcgtc gagcagccgc cgggccaccg
     7381 ccggatccag ccacgcctcc ccggcggcca ccgcccggat cgccgacacc agctcggcgg
     7441 gcgcggcgtc cttgagcacg aaaccggaag cgcccgcccg caacgcggcg tgcaccgcct
     7501 cgtccacgtg gtacgtggtc agcatgatga tccgtaccgg ccgctgcgga tcgtcgatga
     7561 gctgctcgtc ggccatcagc ctcgtcgcgg ccagcccgtc ggtgccgggc atccgcacgt
     7621 ccatcagcac cacgtccggg cgcagccggc gactgacctc gacggcctgc gccccgtcgt
     7681 cggcctcggc gacgacctcg atgtcaggct cgttggtgag cagcatcgcg agtcccgccc
     7741 gtacgagcgg ctggtcgtcg gcgagcagca cccggatcat gaaggctccc gtcgtcggcg
     7801 gccgtgacag cggccccacc acatgatcat cgacgtcgcc gccgtcggcc agcccgatgt
     7861 cgcacagcgg acacgcgttc acccgacagc cggcgccccg ccgtcacccg atgccgccac
     7921 gaggtcgccg cgctgcgcta ccggcagcgt cgcgctcacc cggaacccgc cctcgggacg
     7981 cggcccggcg accaggcgac cgccgacgcg ctccagccgc tcggcgaggc tggccagccc
     8041 gttgccggtg gacagtcccg ccgccgcgcc cgggtcgcgg cccgtgccgt cgtcgtcgac
     8101 gcgcagcaac agcacccgct cctgccaccc gaaatgaaca gtcgcgcagg cccgccggcc
     8161 gacgtgcttg agcgtgttcg tcaggctctc ctgcaccgtc cggtacgccg ccagctcgat
     8221 actcggatcc agcggccggg cactgccgga caccgacatc gtcacggtga gccccgcgca
     8281 ccgcatcgac gtcagcagta cctcgatgtc gtccagccgc ggctgcgggc cgggctcacc
     8341 gtcgaccgcc gggcccgact cggcgcgcat gaccgccagc agccggcgca actccgccat
     8401 cgcctgctgc ccggcctgct ggatgtgcaa cagcgcctcc cgggtccgct ccggatccga
     8461 cgcgctgatc cgcgccgccc cggcggcctg cagcaccatc accgtgaccg agtgcgacac
     8521 cacgtcgtgc agttccgcgg cgatgcggcg acgctccaac gcgaccgcct ccgcccgcgc
     8581 cacacgccgc tcccgttcca gctgggccac ccgccgccgg tgccgccgca ccaccgaccc
     8641 ggcggtccac gcggccgcgt agatgagcgc gaacatcaac gcggtcacca cgaactcccc
     8701 ggcccgcgcg cccgggctcg gctccacccg gaacgagtcg aacgcgctga gcaggctccg
     8761 cgcgcacgcc gccgtgtacg ccgccgccga caccaccagc ggccgcagcg ccgccaccgt
     8821 gtacaacgcc acgatcaggc ccacccacgg ccggtagtcg tgcagcagga accacatcgc
     8881 cgcgccgtgc acgcactcga acgcgaacac cgcgaccggc gcccgggccc gccaccacag
     8941 ggcgccgacc gacagcaccg cggcgagcac ctgcagccac tgccgggccg gaccgaccgg
     9001 ctcgctctgg atcaccacgg acgacgccgt gaacaggtcg agcaggccca gcaccggcag
     9061 cagcagaaga tcgtgacgcc accaactcgc cgcccgcgcc ggagcggacg gcgccaccgc
     9121 accggtcacc gaggtcatcg gcgggctagg agtcttcggc ggggcagccg atcccgaaca
     9181 accggcacgt ccaggacagc ggcgaaccgt cgtcgtcacc gccgccgtca ccgtcgggcg
     9241 gcggcgtggc cgcgctcacc cggtgcgtgg tcaccggcac cgccggccgc cccggctcac
     9301 ccgcgcggcc cgccccggcc agcaccaccg tcgccacgac gtcggccgcg gcgtccgcgg
     9361 ccacccgcca ccgcccgtcc gcgtcgtcgg cgagcatcgc cagcacccgc cgcaccgccg
     9421 aggcgtccgt gccgtagcca cccggaaccg tcgcgccggc gagggaaacc atcagcaggt
     9481 ccgcctcgtc acggtgcagc accgacacct ccgcgacagt cagcgaccgc gcatccccgc
     9541 cggccacacc caccaggcgc accgcgtcgc cggaccgggc ccggcccgca ccgacagtcc
     9601 tcagcagaca acgccgaccg tccaacggca ccccacgcgc gactgtcacc cacccggccg
     9661 gccgctgcgc ctgcaggaac accaccatcg gcggcgactg gacctcggtt ctcatcacgg
     9721 acctccacag aaggaattgc gggcgaacag cccgcgtacg cgagaaattc tggcccacac
     9781 cggcccgccg gacgtccccg taccgggtga catccggtgt caccttccag acggaccccc
     9841 gacgcccacc accgggccgg gacggacacc gaacctcgcc ccacggccgg acgccaggac
     9901 cggccggtga ccaccacgat ggaaccagtc cggacgacag cggcaacaca ccgaacaccc
     9961 cggacaccct tcccaacccg tcacggccgc gaggtttgcc atgcccacgc ccggtgcgtt
    10021 cctgatcgcc gacccggtcc acgtcgactc accggcgtac gtcgccgacg cggcgagccg
    10081 gttcccgctg gccgaccaga ccccgcccga cggctggcgc gtcgccgagc acggcggctg
    10141 ggtcatgtgg cacccgccgc acgcgcagct gccgcagcag ggctggaagg tgcacgtctc
    10201 ggtgaacctc gacgacgccg ccgacgccct cgacctggta cgcgagcact gcgtccgcca
    10261 ccggatcgcc ttcaagttcc agcgcagccg acgcctcgcc ctggtcaaca acgagaagta
    10321 cgcccaccgc gccggcagcg gcaaactcgc cgccctctac ccggccgacg acaccgccct
    10381 gcgccgcatc ctcgacgacc tcggcgccca gctcgccggc taccgcggcc cgtacgtcct
    10441 cagtgacctg cgctggcacg acggccccct ctacctgcgc tacggcggat tcgccgaact
    10501 ctggtgcgtc gacggcgacc atcccgtccc cgccgtcaca cgccccgacg gaaccctcgt
    10561 ccccgaccgc cgcgaacccg tcttcacagt gcccgactgg gcccccgtac ccgacttcgt
    10621 cgccgaacac atcgccgccg tcgacgcgca gaccgacgac gaaccgccct accgcatcga
    10681 ggaagccctg caccactcca acgccggcgg cgtctaccgc gccaccgacc tgcgcgacgg
    10741 ccgcaccgtc gtcctgcgcg aagcccgccc gcacgccggc ctcgacggcg ccggcaccga
    10801 cgcgctcacc cgcctacgcc gcgaggagga catgctgcgt cggctcgccg gcctcgactg
    10861 cgtcccacaa ctgctcgacc gcctcacctg gtgggaacac cagttcctgg tcgaggagca
    10921 catcgagggc gacaccctcc agcaccacct cgccatgcgg cacccgctga tccaccccga
    10981 ccccacccac caggacctga ccgactacac cacctgggca ctccacgtca tcgaccaggt
    11041 cgaagccgcc cttgcccagg tacacgccag gggagtggtc ttcggcgacc tgcacaccgc
    11101 caacgtcatg atccgccccg acggccgcgt cgtgctcgtc gacttcgaac aggcgtacct
    11161 gaccgacgag gacttcaccc cgtcactggg cgaccccggc ttcgccacac cccggatccg
    11221 ccgcggcccc gccgtcgaca cctacgcgct cgcctgcctg cgcctcgccg tcttcgtacc
    11281 gctgacacca ctcgccgcgc tgtgcgacga gaagttcgac gacctcctca cagtcgcccg
    11341 acgcttcccg ctaccgcccg gctacctcga ccgcatccgc gacgacctgc acaccgcact
    11401 gaacccaccc gcgcccgacc gccgccgcgt cacccgctac ccctggcccg ccgaccagcg
    11461 ccgcctgatc gaatcactgg ccgccggcat ccgcgccacc gccacacccc accgcaccga
    11521 ccggctcttc cccggcgacc ccggccagtt cccgcacggc ggcgccaccc tcgcgcacgg
    11581 cgccgccggc gtcatctggg cactcgtcaa caccggcgtc gactaccccg aacgcgacga
    11641 acacctcgac tggctcaccc gcgccgcccg ccgcctgccc accgcccacc tcggcctcta
    11701 cgacggcctg gccggcatcg ccgcgctcct cgaccgcacc ggacgccacg acgacgccgg
    11761 tgaactgctc gaccgatgtc gcaccggcct ccaccaccgc tacggccccg gcctgcacag
    11821 cggcctcgcc ggcatcggac tcgccctgct ccgccccggc agacccgccc ccgacgacgc
    11881 cctgcacatc ggcgaccgac tcgcccgcac cctcgccggc gacacaaagc aacccgtgcc
    11941 cgaacccgca cgccccggcc tgctccacgg ctggtccggc cccgcgatct tcctcacccg
    12001 cctccacgaa gccaccggcg accccgcctg gctacgcgcc gcccgcaccg ccctgcgccg
    12061 cgacctgcaa cacaccgtcc gcgacgacaa cggcaacctc cacgtacgcg acggcgcacg
    12121 acggctgttc tacctcgacg aaggcagcgc cggcatcgcc gtcgccgcac acacactgct
    12181 ccgccacggc gaacgccagt ggctgcgcga cgtcgtcacc accgtccgcc gcaccatcga
    12241 cgtcgaattc gtcctgctgc ccggcctctt ccacggccgc gccggactac tcgccaccgc
    12301 cgcactgctc accgacgacc caccgcgcgg caccaccccg cacggtcccg tcggactcgt
    12361 ccgcgacgac gcgccccacc acgtccccgc gcacctggcc cgcctcgcct ggcacgccta
    12421 cgccctcgac ggccggctcg cgttccccgg cgacaccctg ctgcgcatct ccaccgacct
    12481 cgccgccggc ggcgccggaa tcctgtccgc gatacacgcc gcgctgcacc gcaccgcagt
    12541 gacgctgccc ttcctcgacg cacccaccca cgtcgcgccc accggccacc tcctcgccgc
    12601 gagctgagac ccgcccggcg cccacagacc ccgtcggaac caccgacggc caaccccacc
    12661 acacccgaga aggaggtgaa cccccatgac gaagctcctc aacctgcagg ccatggccac
    12721 gcagaacggc acccgccacg cggtcccgcc gcagtccagc agcatcagca tcgcctgctg
    12781 caacggctga gacggcagtg gcgaacgggc cgccggcccc agccacacct gatccgcctg
    12841 gcgacccggg cgggcggcca ccgcccgccc gggtccgtcg tcaacccgcc ccacagccgg
    12901 tggagccgac ctcccgcccg ccaccacgcc cacggagccc tcatgccgcc caccggcctg
    12961 cgacacaacc gcgacttcct cctcatcacc gtcgcccgca ccgcgtcgaa actcggcacc
    13021 caggtcaccg ccgtcgccac gccgctcctc gtgctgctga ccaccggctc cgccaccgac
    13081 gccggcctcg tcgccttcgc cgaaggaatc gccctggtcc tcgtactcct gcccgccggc
    13141 ctgctcgccg accgccgcga ccggcgcatc ctcatgctct gctgcgacgg cggcgcgctg
    13201 ctcgccgtcg ccggcgtcac agtgctcgcc ctcgtcggac acgcgcccgt cctgctgatc
    13261 gccgtcctcg ccgccgccac cgccggcctc ggcgccgccc tgcaacccgc cgccgcggcg
    13321 gccacccgcg ccgtcgtccc ggcccgggac ctgcgtacgg ccaccgtgtt caacgaaacc
    13381 cgcaacggag tcgtacacct ggccggccca ccgctcggcg gcttcctgtt cggcctcgcc
    13441 ccggcactgc cgttcctcgt cgacgcgatc tcgtacgccg tctccctggt cgctgtggcc
    13501 ctgctacgcg gcccgctcgg ccgctccctg accacgccgg gggagtccct gccccagcag
    13561 gccgtcgccg gggtccggtt cctgtggcgg caaccgtcgc tgcggttcac gctgctctgc
    13621 ggcgccgtcc tgaacttcgc gttcgcaggc gtcctgctgg cgatcatcgt cgtgccggtc
    13681 cgcaacggcg cctccggact gtccgccgga accgtcatgg catgcgtcgg gctcggcgcc
    13741 gtcgccggat cactcgtcgc gtcctggctg accgcgcggg tacccacccg ctggctgatc
    13801 ctcgctgtcg tctgggcctg cgccgtgctg accgccgcga tggccaccac cgacaacgga
    13861 ctgatcctgg gcgcgctggc cggcgcctgc gtcctggtcg tacccgccgc caacatcagc
    13921 atgctgaccc tccagaccct gctgaccccc ggcgacctgc aggggagagc gaacgccgcg
    13981 accagcttca tcgcgctgat cgtggcgccg ttcggcccgg ccctgtccgg cctgctgatc
    14041 gaccgcgtac cggcgccggt ggtgttcggc agcttcgcgg ccgtcatgct gacgctcgcc
    14101 gtgggcgcgg ccgtcgcacc cgccgtgcgc gccatgcccg atctgcgcgc cgtcgaggac
    14161 gtcgcggagc ccgagcccgg cgaggccgag cggcgcgacc cgcagccggt ctgagtcgat
    14221 ctccgtaccg gcaggcaggg gagaggcgtc ggtcttttcc ggggacgttc ggatgatcac
    14281 gacagcgcac cgcccgtgcc accatgtagg gcccctccca ggacaggcca caagggacga
    14341 ggtgccggca tggatctgcg taggagccga cagacgctgt ggaagggcct cacggtcttc
    14401 ggagtcggcg tgtttccact gctgtacctc acgtccgcgt cgaccggacg atggatcgtt
    14461 ctcggcctgt ggctggtgtc ggccggcgtg ttcgtcgcct accagctcag gccgttccgg
    14521 ttccgcatcg gagccgacgg actggacctg cgggtcgccg ggctcaaccg gctggtggcg
    14581 tgggccgaga tcgacgccgt cgtcctggac cagccactac cgtccggtgg ccggaagcag
    14641 cgagccgcgt cggtgctgct ggtgccggcc accgcctcga ccatcgatcg tcggctcacc
    14701 gggcggagcc cggtcgacgg ccgcccggcc ctggtgctgc tcgacctcga tcaggtgcag
    14761 cagccggcgg acgaggtggc ggccgccctg gcccggttcg gagcaagccg cttcgcggac
    14821 gtccggcagc gagccccgga acggtccgac gacccgggtg cgccggacat ggaggccctg
    14881 acgttgttgg ccgacctgac accgcgagtc cagaaggcgc tcgactcggg gcaggcgtcg
    14941 cagcggcagg cggtcaaggc agaggtggac gcggcactcg cgaggctgcg cgaggcaccg
    15001 gcgggtagtg accagccacg gttggccgcg cttctgaagg tcatgtccga aactctcggc
    15061 gaagagggcg aaggcgtgaa ggcgtcctga gcactgccac gcgctgagtc gccgattcga
    15121 taatgtacat tatgtcaagc tgggctcagg aggggtcccc gggcgccacg ctaggccact
    15181 gaccgacctt ccgggcttgg aggtccaacc ggtcgccccg tcgcaccgcc gaactcggca
    15241 tcagctcgtc gtccaccgcg cggtccggcc agttggtacg cacccaggcc gcgatgccgc
    15301 tggcgcttga ccgcgagcac cgatcgcccg ggtgcccccc gagcacgaat ctcgccgaca
    15361 ccggcctcca cgccgcccac tcacccccat cccacccatc cggcgatcat gaggttggcg
    15421 ggggcaaatt ggacagcgtc cgcggtcaac ctcatgatcg ccggagcaga gagggtgccg
    15481 gcccttccgc ctgccctccg gtgcccgacc gagtgcccga cgggtgtgac tgccgccagt
    15541 tcgccgatgt ggctgcatcg gagcgcccgg gttgccgcaa cctcggcgag gtggagttga
    15601 tcatcgcttg agcgactgcg ctccccctgg accggccccc tggcgggaac gcgagaatca
    15661 tgcataatat cccttatgca tgacaaaccg gacgaaacgg taggggtcct gatcgaggag
    15721 ttcctgaccg cccgggccac ccgcaagccc tccccccaca ccctggccgc gtaccggcgg
    15781 gacctgacca cagtggccga gctcgtcgcc gccgacggtg acaccactcc cctccccctg
    15841 gaccggctgg cggtcgggag cctgtccccc agggtgatgc gcgcggcgtt cgcgaggttc
    15901 gccgctcccc gcgccgccgc gtcggtccat cgtgcctggt cgacgtggaa cagcttcttc
    15961 actttcctgg tggcggaggg cgtcgtaccg ggcaacccga tgccggcggt ggggcgaccg
    16021 cgtacgccgc tcccccggcc caagccgcta cggggcgagg acactccgga ggaactgctg
    16081 gcggcggtgg cgcgcgcgga gggcaggcag cgtgatccgt ggccggagcg cgacctggcg
    16141 gtgctggcgc tggcgttgtg cgcggggttg cggctgtcgg agctgctggc gctgcgggtg
    16201 tcgtcggtgg cggggcgcga cggcgagcgg cgggtggacg tggcaggtaa gggtgggcgt
    16261 ccgcgtacgg tcccgatcga ggatgccgtg gaccgggtgc ttgcgggtta cctggacagc
    16321 cggcggtacc ggttcgggtc gcgaagtgtg cggccggacg cgccgtttct ggtggaccgt
    16381 cagggtgagg cgttgcggcg gggtgggctg cagtacctgg tggagtcgtg ttaccggcgg
    16441 gcgggcatcg gtgaccgggt gccgcggggc gcccggttgc acgcgttgcg gcacacgttc
    16501 gcgacgcggt tggcggagga cggggcgagc gcgtcggaga tcatgcggtt gctggggcat
    16561 gcgtcgttgg cgtcgtcgca gacgtacatc gaggtgacgg cgggtcagca gcgggcggcg
    16621 gtggcggcga accgtaccaa ccgggctttg tcggggttga cgccgcggcg gtgagggccg
    16681 cgcggcggtc tgccgtgctg gcaggatcgg gcggatgcgg gtgggtgcgg cacgggcggt
    16741 ggcggtcggt tgggtacggg agcggatgcg cgtcgatccg tcgatcgagg gggcgttctt
    16801 cagcggttcg actgtggggt tgccggacga tgcggtgctg ccgccgtggt cggacgtgga
    16861 cgtgttgctg gtgcgctgga accccggcgt gaaggtgggc aagttcgtgc accggggggt
    16921 gctgctggag gtcagcactg tcacctggga ggagttgggc ggcccggagg atgtgctggg
    16981 gtcgtgggtg ttcgcgccga tgttccgtac cgatggggtg atcgcggatc cgtcgggccg
    17041 gctggccgcg gtgcgggagc gggtggcggc ggggttcgcg gatccggtgt gggtgcgggc
    17101 gcggtgcgcg ggcgtgcggc ggcggatcga ggccgggttg cgggcggtcg gcggttcggc
    17161 gccggtggcg gagcaggtgc tggcgtgggt gtttccgacg tcgttgctgg cggtgtggcc
    17221 ggcggtggcg gggctggcgg atccgacggt gcggcggcgg tacgtgcggg cggagcgggt
    17281 gttgtcgcgg ttcgggttcg ccgatcggta tccggagctg ctggacacgt ttgacggcgg
    17341 tggggtgggt gtggacgcgg cgcgggtgcg ggcgcatctg gccgggttgg cggtggtgtt
    17401 cgacgaggtg tcgcggttgc cgcgggaggg gttcgcgttc ggggcggatc tgggcgctgc
    17461 ggggcgtccg gtggtgttcg acggtgcggc tgagctgatc gcggcgggcc ggcatcggga
    17521 ggcgatgttc tgggtgctgg tgacgtacgc gcggtgtcat gtggtgttgg gcgcggtggc
    17581 gccggagcgg gagcgggcgt tcggggcggt gctggcggat ctgggtgtgg cgtcggcggc
    17641 ggatcggcgg cggcgggcgg acgcgttgct ggcggcgttg ccggggtggc agtcggtggt
    17701 ggatgcggtg gcggcggagg ctgtggcagg ctgagggaga acgcgactgg cggcacgggg
    17761 atgggtgaac catcggggag ctcgtcgtgg gggtcgaccg cctgggcctc cgcgggcgag
    17821 gtgtcgtatg tcttctgcac ggttgttgcc gggtgccccg gtggcggagc gggtgttgtc
    17881 ggaggtcgcc gcgtcggtgg cggagctgcg cgcggcgggt gtgacgccgg cgctggcgac
    17941 ggtgctggtg ggtgacgacg acgcgagcgc gggctacatc cggatcaagc aacggcaggc
    18001 ggcggagctg ggtttcgtgt cgccgcacgt gcatctgccg gcgtcggcgt cgcaggcgga
    18061 tctgcacgcg gtgctggcgg atttcaacgc ggacaagacg gtgcacgggg tgctggtgca
    18121 gtatccgatc ccggggcgtc tggactacga ccgggcgttg gcggagctgg atccggacaa
    18181 ggacgtggac gggatgcatc cggtgaacat gggccggctg gcgttggggt tgccgggtcc
    18241 gttgccgtgt acgccggcgg ggatcgaggc gttgctggcg tttcacggtg tgccggtggc
    18301 gggccgggag gtggtgattc tgggccgggg tgcgacgttg ggtcggccgt tggcgatgtt
    18361 gctggcgcag aagcggccga cggcgaacgc tgcggtgacg gtggtgcaca cgggggtggc
    18421 ggactggccg cggtacacgc ggcgggcgga gatcctggtg gcggcggcgg gggtgccggg
    18481 gatcgtgcgg ccggagcatg tgcgtccggg tgcggtggtg gtcggtggtg gggtgcggta
    18541 cgaggggcgg cggttgctgc cggacgtgga cgagtcgtgt gccgaggtgg cgggcgcgat
    18601 cacgccgcgt gtgggcgggg tgggtccgac gactgtggcg atgttgttcc gtaacgcggt
    18661 ggaggcggct cggcggcaga gcggtctggg ttgagcgtca gccgaggtcg acgacgaggg
    18721 gccggtggtc ggagatggtg gccagcgggg tgtgcacggc ggtgaccggt gggaggcggt
    18781 cgagggcgtg ccggtcggcg aggatgtggt cgagttggac gcggggttgc ccggccgggt
    18841 aggtggggcg gcgggccagg ggtcgccagc gggtgagcgc ggcggcgggt ccggcgggca
    18901 ggttgaggtc gccgagcagg atgcggggcg cgggcagggt gcgcagggcg cggacgacgc
    18961 ggcgtagctg ccagacgttc cagccgggga cgaaggacag gtgggtggcg gcgacggtga
    19021 gggggccgtg gggggtgtcg aggacggcgg cgagtacgac gcggggttcg tcgcggagca
    19081 ggatgaggcc gccgccgggg ccgggcgcgt agatgggtga gcggacgggg gcggcgcgta
    19141 gccgggtgac ctgccaggag cggacggggt ggcggctgat caggccgatg ccgtagaggg
    19201 gttcgccgtg gccgtcgtcg tcgtgggtga gggggcggaa ctgttcgccg ggggtgccga
    19261 cgacggcggc ggcgaagcgg tggtggtcgg cgtgcagggc gcgggcggcc agggcggtga
    19321 ggtcgagttt gccgctgcgg ctctggtcgc agtcgacttc ctgcagggcg aggacgtcgg
    19381 cgtcgagggc ggtgacggcg gcggtgagcc ggtcggggtc gacgagtccg tcggtgagtg
    19441 atcggccgtg cagcaggttg aaggtggcca ggcgcacctg gacaccctac gtcgtcgtgg
    19501 cagtcttgcc gggtgctgag actgttgtgc tgttcgatgc tggtgttcgt ggcggtgggt
    19561 tcggtggggg tgtggttgcg gcgtcgccgg ggccggtgag gctggccaca ggtggccttg
    19621 tcgctggtgg cggggtaggc agaatgcggc ggtggatgcc ctgtcgttga cgacgttgct
    19681 gaccgctgcc cttgtcgccg ggtgggtgga cgcggtggtg ggtggtggtg gcctgttgtt
    19741 gttgccggcg ttgctggtgg cggcgccggg ggtgccggtg gcgacggcgt tggggacgaa
    19801 caagctggcg gcgatcttcg gcacgtcgac ggcggcggtg acgtatgcgc ggcgtacgaa
    19861 gctggactgg gcggtggcgg gtccggcggc ggggttggcg gtggtgacgg cggggttggg
    19921 tgcggcgttg gcgggtgcgg tgccgggcag cgcgtaccgg ccggtggtgc tcgtggtgct
    19981 ggtggcggtg gcggtgttcg tgctggcgcg gccgtcgttg ggtgtggtgt cgtcgccgcg
    20041 gcggacgccg aggcgggtgg tggtggcggt ggcggtggcc gggttgggca tcgctctgta
    20101 cgacgggttg atcgggccgg gtacggggac gtttctggtg ttggcgttca cggcgattct
    20161 gggttcggat ttcgtgcacg cgtcggcgat ggcgaaggtc gtcaacgcgg gcacgaatct
    20221 gggtgcgctt gtggtgttcg ggttgaccgg gcatgtgtgg tgggcgctgg gcgcggcgat
    20281 ggcggtgtgc aacgtggtgg gggcggcggt gggcgcgcgg atggcgttgc ggcggggtgc
    20341 cgggttcgta cgggtggtgc tgctggtggt ggtgctggcg ttggtggttc ggttgggtta
    20401 cgaccagtgg gtggcgggct gatcgcggtg gcggtgcggg cggagcacga tcgggcggtg
    20461 ctggcgggtc tgctgggccg ggatccggtg ttgcacgcgt accagttggg tgatctggac
    20521 gatttcttct ggccgtacac gtcgtggttc cggcgtggcg accaggtggt gttgctgtat
    20581 cacggggtgg agttgccgac gttgctggcg ttcgcggcgc cggatcgggt ggcggagctg
    20641 gcggggttgc tggcggaggc ggcgccggtg ttgccggcgc ggatgtgggc gcacctgtcc
    20701 cccggtctgg aggcgacgct gggccgctgg ttcgtggtgt cggaggcggc ggcgcatcac
    20761 cggatggcgt tgacggatcc gggccggttg gcggcggtgc cggcggtggg tgaaccgttg
    20821 gggccggcgg acgcggcgga gctggccggg ttgtacgcgg tggcgtatcc ggggaactgg
    20881 ttcgacgcgc ggatgctgga gacgggccag tacgtggggg tgcgcgagcg tggccggctg
    20941 gtggcggtgg cgggggtgca cgtgttctcg ccgcggtggc gggtggcggc gctggggaac
    21001 gtgacgacgc atccggatgt gcggggtcgt ggtctgggcg cgggggtggt ggcggcgttg
    21061 tgtgcccggc tgctcacgtc ggtggatcat gtgacgttga acgtgcaggc ggacaacgcg
    21121 gcggcggtgc gtctgtacga gcggttgggg ttctcccggg tggccgggtt caccgagtgc
    21181 gcgttgacgt cagcggccgc ggctgggtga gtcgaagcgg ccggcgcgga tctcgcgcag
    21241 ggcccgtcgg cgggtgtcgc cgcgcagggt gtcgacgtag aggcggccgc gcaggtggtc
    21301 ggtctcgtgt tgcagggcgc gggcgaggaa gccgctgccg gtgatggtga gcggttcgcc
    21361 gtgctggtcg tagccgtggg cggtggcgtg cagcgcgcgg ggggtcggga agtacaggcc
    21421 ggggatggac aggcagccct cgtcgtcgtc ctggagttcg tcggacacgt ccagggtggg
    21481 gttgaccatg tggccgcggt ggccgtcggc gtcgtagacg aacacctggg cgttgacgcc
    21541 gatctggggt gcggcgacgc cggcgcggcc gggcgcgccg agcagcgtgt ccatcaggtc
    21601 ttcgacgagg gcgcgtagtt cggcgtcgaa gctggtgacg ggttcgctgg gggtgcgcag
    21661 gacggggtcg ccgatgatcc ggatcgggcg catagtcatg tccggaaggc tatccgttgc
    21721 ttaccggtct gcggtgtccg gtggggtgtc gagcacgccg gtgtcggcga tgcggtcgcg
    21781 cagggggcgg cggcgtagcg cgtcgaggac ggcgtacagc tcgtcggcga gtggcaccgg
    21841 tagttcggtg tcgaggtggc gcatggcggt ggtggtggcg gcccattcgg cttcgacggc
    21901 gggcagcagg gcgcgggcgc ggtcggtgag ggtgacgatg cggtggcggg cgtcggcacc
    21961 ggggcgcagg tcgacgaggc cggcgcggcg catctgggcg atggtctggc tggcggcgga
    22021 gtgggtgacg ccgacgcggg tggcgaggtc gcggatgggc agcgggccgt cggcgacgag
    22081 cgcgcgcacg actggtgagt agcggggccg gtagtcggtg aggccgaggc ggtggtggac
    22141 ggcggcgacg tcgccgtcga ggacgtccag gacgtggcgt agcagggtgc cgagggcgtc
    22201 gcggtcgggg gcggtcacgt ccactaatgt aacagcgctg ttgtatctgt ctgaggaggc
    22261 cgcctgatgt atccgccgat cgagccgtac gcgcagggca tgttggacgt cggggacggg
    22321 cagagcgtgc actgggagac gtgcggcaat ccggccggcc gtccggcgct ggtggtgcac
    22381 ggcggcccgg gttcgggggc gggcgcgtcg tggcggcggc tgttcgaccc ggccgcgtac
    22441 cggatcgtgc tgttcgacca gcgcggctgc gggcgcagca ctcccccggc gtcggatccg
    22501 gccaccgacc tgtcggtgaa caccacggcg catctgctcg ccgacatgga gctgctgcgc
    22561 gtgcacctgg ggatcgacag gtggctgctg tgcggcgcgt cgtgggg
//
