LOCUS       NZ_CP030865            22146 bp    DNA     circular CON 14-AUG-2024
DEFINITION  Micromonospora sp. B006 chromosome, complete genome.
ACCESSION   NZ_CP030865
VERSION     NZ_CP030865.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora sp. B006
  ORGANISM  Micromonospora sp. B006
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Complete Genome of Micromonospora sp. Strain B006 Reveals
            Biosynthetic Potential of a Lake Michigan Actinomycete
  JOURNAL   J Nat Prod 81 (9), 2057-2068 (2018)
   PUBMED   30110167
REFERENCE   2  (bases 1 to 7040153)
  AUTHORS   Braesel,J., Crnkovic,C.M., Kunstman,K.J., Green,S.J.,
            Maienschein-Cline,M., Orjala,J., Murphy,B.T. and Eustaquio,A.S.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-JUL-2018) Medicinal Chemistry and Pharmacognosy,
            University of Illinois at Chicago, 900 S Ashland Ave, Chicago, IL
            60607, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SPAdes v. 3.5.0
            Expected Final Version            :: yes
            Genome Coverage                   :: 77.6x
            Sequencing Technology :: Illumina; Oxford Nanopore MinION
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003408515.1-RS_2024_08_14
            Annotation Date                   :: 08/14/2024 03:31:08
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,342
            CDSs (total)                      :: 6,278
            Genes (coding)                    :: 6,199
            CDSs (with protein)               :: 6,199
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 79
            CDSs (without protein)            :: 79
            Pseudo Genes (ambiguous residues) :: 0 of 79
            Pseudo Genes (frameshifted)       :: 20 of 79
            Pseudo Genes (incomplete)         :: 62 of 79
            Pseudo Genes (internal stop)      :: 6 of 79
            Pseudo Genes (multiple problems)  :: 7 of 79
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:07:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 229068
            Orig. end                         :: 251214
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP030865.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22146
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22146
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22146
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12146]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12146
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(92..496)
                     /locus_tag="MicB006_RS01135"
                     /pseudo=""
     CDS             complement(92..496)
                     /GO_function="GO:0030612 - arsenate reductase (thioredoxin)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013476370.1"
                     /locus_tag="MicB006_RS01135"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="arsenate reductase ArsC"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSDKPSVLFVCVHNAGRSQMAAAWLRHLAGDAVEVRSAGSEPADR
                     INPVAAEAMREVGIDLTG"
     gene            complement(493..1230)
                     /locus_tag="MicB006_RS01140"
                     /old_locus_tag="MicB006_0231"
     CDS             complement(493..1230)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015267 - channel activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074323.1"
                     /locus_tag="MicB006_RS01140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0231"
                     /product="MIP/aquaporin family protein"
                     /protein_id="WP_116503256.1"
                     /transl_table=11
                     /translation="MTLALPRRASAEFAGTALLVTAVVGSGIAATRLSPSDVGLQLLEN
                     AIATALALGALILIFGPVSGAHLNPVVSAVDWWLGRRAGTGLTGPDLVAYAVAQVGGAI
                     TGAVLAHLMFGLPAATWSRTVRGGSHLLLAEVVATAGLVVLVFALARSGRTAAAPAAVG
                     AWIGAAYWFTSSTSFANPAVTVGRAVTDTFAGIAPGSVPGFLAAQLAGGVLAVAALALW
                     YPHAADTAGDVVVPHLTRETEAR"
     gene            complement(1227..1586)
                     /locus_tag="MicB006_RS01145"
                     /old_locus_tag="MicB006_0232"
     CDS             complement(1227..1586)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020513922.1"
                     /locus_tag="MicB006_RS01145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0232"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_116503258.1"
                     /transl_table=11
                     /translation="MSKQALPIVDLDAVACCPPMSVRPMEPDQAAVVAPMFKALGDPIR
                     LRLMSMIASVPEICVCDLTPAFDLSGPTISHHLKVLREAGLVDSERRGTWVWYRVRPDV
                     FRQLGALLQIPAHDS"
     gene            1663..2100
                     /locus_tag="MicB006_RS01150"
                     /old_locus_tag="MicB006_0233"
     CDS             1663..2100
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283444.1"
                     /locus_tag="MicB006_RS01150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0233"
                     /product="ArsI/CadI family heavy metal resistance
                     metalloenzyme"
                     /protein_id="WP_116503260.1"
                     /transl_table=11
                     /translation="MSRVQLALRVSDLEGSVAFYSKLFGVEPAKRRPGYANFAVENPPL
                     KLVLLEGEPGLPTVMDHLGVEVATTDEVNAATNRLTESGLITLEENDTECCYALQDKVW
                     VRGPGDEPWEVYTVKADSPQLEKVTESACCASDAAEQPAAV"
     gene            complement(2192..3151)
                     /locus_tag="MicB006_RS01155"
                     /old_locus_tag="MicB006_0234"
     CDS             complement(2192..3151)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473453.1"
                     /locus_tag="MicB006_RS01155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0234"
                     /product="hypothetical protein"
                     /protein_id="WP_225980600.1"
                     /transl_table=11
                     /translation="MLRTALAPVLVLAVILLGGCGRVSGLLDRVSLFHPVWAADGWVYY
                     LREVTSTSSSGVAEVWRQRPDGSAEEPVLTRAPAVSTCEAGLFSFLFAGPDGDLGVALE
                     CGWDGTELLSYSPADKTFEPLASTRFLVDAALVNGGRGGYVEAPRKCGPGGIQLLADGK
                     AYEFGSPVTVGGATFNPSGGDTDCGSTVLARSPAALGERLFFITAPDSLGRLPLPPEVS
                     PNDLTWHLTEWDVGSATARFLTELPGLANLAVSPDGRSVIAAVASDHVGGVWSVDVGSG
                     KKTRIANGARAYHPSFSPDGKRFVYVEAFARLKFAKAR"
     misc_feature    3207..3220
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            complement(3310..3720)
                     /locus_tag="MicB006_RS01160"
                     /old_locus_tag="MicB006_0235"
     CDS             complement(3310..3720)
                     /EC_number="3.5.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510277.1"
                     /locus_tag="MicB006_RS01160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0235"
                     /product="RidA family protein"
                     /protein_id="WP_116503264.1"
                     /transl_table=11
                     /translation="MRLTLDNPASVAAPFGDRFAHVARIDVGGGALLMLAGQVAVDDDG
                     KVVAPGEPGAQAERIFEIVDGVLAAHGACFDDVLHIRTFMTDLADLPAYAAVRRRVFTG
                     TPPPASTTVEISKLFLPGAVLEVEVTAVVRSR"
     gene            complement(3720..4544)
                     /locus_tag="MicB006_RS01165"
                     /old_locus_tag="MicB006_0236"
     CDS             complement(3720..4544)
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /locus_tag="MicB006_RS01165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0236"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_225980601.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.7e-06, bitscore:
                     26.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIIAVLGTGHMGTPIARRLLAGGNRVRVWNRSPERSEPLAAVGA
                     TVAASPSAAVDGADVVVVMLADAAAVETVLFGPDGAATALRPGTVVVQMSTIGPDEVRA
                     VAGRLPAGVSLLDAPVGGSVNAAHAGTLVIFAGGPADAVERAAPVLEQLGSVRHCGPIG
                     AGAAVKLVANTGLVTAVAALHDALAVAAALGVDRQTALDVLGRGALAGAVGRVTAPGAS
                     FAVAMAAKDARLALRRPVPAPVLEAALDLMQAAPDQDADLSSLVSADFLKGR"
     gene            4624..5520
                     /locus_tag="MicB006_RS01170"
                     /old_locus_tag="MicB006_0237"
     CDS             4624..5520
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020510278.1"
                     /locus_tag="MicB006_RS01170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0237"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_116503268.1"
                     /transl_table=11
                     /translation="METQLLAVFRTVARHGSITTAARALRFTQSAVSRQIAALEADIGA
                     RLFDRLPRGVALTEEGRELLPHAEAVLDRLAAVRRDLEDLRGLGRGRLRVGAFPTAVAA
                     LVPRAMASFRSAYPEISLSLVEGVTPRLLERLLAEEADVAVVSTSPTGELDRERFDLRH
                     LLDERLLVAVARDHRLARRRSVRLAELAQDAFVVGSATAENTLLRASLPSGFSPRIDIV
                     AAEWTGKLGCVAAGLGVALVPALAVRGTPPDIALLRLHPDDESVRQIFAATVRGRTPSP
                     AVMHFLEHLRAEAAHLG"
     tRNA            complement(5630..5703)
                     /anticodon=(pos:complement(234735..234737),aa:Phe,seq:gaa)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MicB006_RS01175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MicB006_0238"
                     /product="tRNA-Phe"
     gene            complement(5630..5703)
                     /locus_tag="MicB006_RS01175"
                     /old_locus_tag="MicB006_0238"
     tRNA            complement(5780..5853)
                     /anticodon=(pos:complement(234885..234887),aa:Asp,seq:gtc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MicB006_RS01180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MicB006_0239"
                     /product="tRNA-Asp"
     gene            complement(5780..5853)
                     /locus_tag="MicB006_RS01180"
                     /old_locus_tag="MicB006_0239"
     tRNA            complement(5887..5959)
                     /anticodon=(pos:complement(234991..234993),aa:Glu,seq:ttc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="MicB006_RS01185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="MicB006_0240"
                     /product="tRNA-Glu"
     gene            complement(5887..5959)
                     /locus_tag="MicB006_RS01185"
                     /old_locus_tag="MicB006_0240"
     gene            complement(6103..6888)
                     /locus_tag="MicB006_RS01190"
                     /old_locus_tag="MicB006_0241"
     CDS             complement(6103..6888)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013730889.1"
                     /locus_tag="MicB006_RS01190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0241"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_116503270.1"
                     /transl_table=11
                     /translation="MRPRALPALALGLVLLVTACGDAGKSPEQAAASPSVPASPSPATE
                     PSPTPTPTPRKPKLRPVPKKLPAGLHRASGSSGVALTFDDGPDPRYTPQILAQLRAARV
                     TATFCVVGQQAKRYPELVARIVREGHQLCNHSWHHDVNLGRRSAAEIRADLERTNDAIR
                     AAAPKAPITWFRQPGGRWTAEEIVVARQMGLRPLHWSVDPQDWDHPPAKTIIKRVTGAT
                     RHGSVVLMHDAGGDRAQTMAACRHLIPDLKRRYGIAHLR"
     gene            complement(6963..7910)
                     /locus_tag="MicB006_RS01195"
                     /old_locus_tag="MicB006_0242"
     CDS             complement(6963..7910)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018255064.1"
                     /locus_tag="MicB006_RS01195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0242"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_116503272.1"
                     /transl_table=11
                     /translation="MADEALSAGAVARRLGVAVTTLRTWHQRYGLGPSEHVPGHHRRYT
                     PADLARLEIMRRLTAEGVAPAEAARWARQAPAVLPPDRLALKARTSAVRDGGGTTIPVG
                     RAGPAARGLARAAMRLDSVTIARTIADALAADGVVATWEGLLRPVLTGIGERHAATAGL
                     IEVEHLMSRCVSVAFATVIRAHPNGGPPRILLSCADEEQHSLPLEALAAALAEAGVSCR
                     MLGARVPVPALVEAVNRTGPAAVVLWSHTRSTADPCQLTALLTVPRRPLLVLAAGPGWR
                     ADSLPAGVVRPVDLAEALSLAVAVRDSLDQSTTG"
     gene            complement(7900..8493)
                     /gene="idi"
                     /locus_tag="MicB006_RS01200"
                     /old_locus_tag="MicB006_0243"
     CDS             complement(7900..8493)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283449.1"
                     /locus_tag="MicB006_RS01200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0243"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_116503274.1"
                     /transl_table=11
                     /translation="MSEREEHLVELVGDDGQVLGETTVATAHQPPGRLHRAFSVLLVDP
                     QGWVLLQQRAAVKTRFPLRWANSCCGHPLPGQSLTEAANRRLAEELGLGPVALTEVGVY
                     IYYAEDPATGRVEFEYDHVLRADVPADLVTRPDPDEVADLRWADPGAVVADLDADPRAY
                     APWLGGVVNRLLPAAGPARPGVAASEAPERSGGR"
     gene            complement(8490..9971)
                     /gene="crtI"
                     /locus_tag="MicB006_RS01205"
                     /old_locus_tag="MicB006_0244"
     CDS             complement(8490..9971)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018222034.1"
                     /locus_tag="MicB006_RS01205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0244"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_192900248.1"
                     /sec_met_domain="DAO (E-value: 1.9e-17, bitscore: 62.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTVKGRTDRVVVVGAGLGGLACALHLAGSGRQVTVLEREPVPGG
                     RAGRLSVDGYEFDTGPTVLTMPDLIAEALGAVGEELTDWLDLSPLDPAYRAYYPDGSTL
                     DVITDTTRMAAEIARVCGPREADGYLRFVDYARNLWQWERADFIERNLDAPTDLLTGNL
                     LKLFANGAFRRLQTKINQFFRDPRTQRIFSFQAMYAGLSPHDALAIYTVIAYLDSVAGV
                     CFPRGGIHAVSRGMAGAAEKHGVQFRYGTTVTRVETANGRATGVITADGDFVPADTVVL
                     NPDLPVAYEDLLPPSRQRKLTYSPSCVVLHIGSTQGYGKIAHHNIHFGRSWKGTFDEVI
                     RRGELMTDPSLLVTNPSRTDPSVAPAGKHTYYVLAPVPNLERAPFDWTGDLTQRYAEQL
                     VGTLEERGYVGFGDGIEVMEAVTPADWAAQGMAAGTPFAAAHSLFQTGPFRPSNLHRKL
                     DNVVFVGSGTQPGVGVPMVLISGKLAAARITGATA"
     gene            complement(10001..11155)
                     /locus_tag="MicB006_RS01210"
                     /old_locus_tag="MicB006_0245"
     CDS             complement(10001..11155)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019901498.1"
                     /locus_tag="MicB006_RS01210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0245"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_073826693.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-48, bitscore:
                     163.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDAVAGNALRVAPAQPGATDDPVRGVLAAFTKDLIKGVDETLV
                     AFLAAEVDSLTEIDAAMGAFAATARDCVLAGGKRVRPTFAYWGWRGAVGGEEPMCSVLP
                     ALSALELLHTFALVHDDVMDASDTRRGLPTAHRAAAARHRAAGHSGDPDRYGEAVAVLI
                     GDLCMVWADRLMSHAAVPAERLLDVRRCYDQMRVETVAGQFLDVLGENDAGNWTVDRAL
                     RVARYKTASYTVQRPLLFGACLAGTDADDPLIAAYTRYGLAVGEAFQLRDDLLGVYGDP
                     ETTGKPAGDDLRTGKPTALLMLARQLADPAQRRVLDRAGSVTTAREVDRLADVVRDTGA
                     TARVERMIADRVTEALAALGTAPIDETARTALTGLATAATARRA"
     misc_feature    complement(11156..11174)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.7"
                     /tool="antismash"
     gene            11220..12146
                     /locus_tag="MicB006_RS01215"
                     /old_locus_tag="MicB006_0246"
     CDS             11220..12146
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785446.1"
                     /locus_tag="MicB006_RS01215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0246"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_116503277.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.5e-113,
                     bitscore: 375.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.5e-64,
                     bitscore: 216.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDVDLAAAYDRCRELHRRHGRTYYLATRLLPAWKRRHVHALYGFT
                     RYADEIVDRTEDLPPAERAARLREWSDRFVAGLHGASVDDPLLPAVLHTIAVFDLDRDD
                     FASFLRSMAMDLTVMSYPTYDDLLDYMEGSAAVIGTMMLPILGSSDPAAAREPARQLGF
                     AFQLTNFIRDVAEDLDRGRTYLPDEDLAKFDVTRADLVAAKDAGRTTPRIRELIEYEVT
                     RAQAHYLAAAPGIPLLNPASQACMRTAYALYGGILDEVAAQDYDVFVRRALVPQRRRMA
                     VAARALLTPAGTPVRVPGPALEPALAG"
     gene            12143..13465
                     /locus_tag="MicB006_RS01220"
                     /old_locus_tag="MicB006_0247"
     CDS             12143..13465
                     /EC_number="4.1.99.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003904 - deoxyribodipyrimidine
                     photo-lyase activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283453.1"
                     /locus_tag="MicB006_RS01220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0247"
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="WP_116503279.1"
                     /transl_table=11
                     /translation="MTGRTAVVLFTRDLRVHDHPALAAACSAFERVVPLYVLDPALQKL
                     SANRTRFLHQSLADLREALRALGGDLVVRRGDPVTETVELARKVGAEGVGLSADVSRYA
                     RRRERRLRAECDRHRMFLRLFPGLTIVEPGALRPSGGDHYRVFSPYFRAWQGVRPRDEL
                     AAPKRVRLPDGVDPGRLPDPPKGDSPAAAAGGESVARRRLTAWLPTLDRYDDIHDDMAG
                     DETSRLSPYLRFGCVSPLTVANRAGDRDGPFVRQLCWRDFYHQVVAGFPDLSTTAYRRG
                     AREDWRYDEHALDAWTEGRTGMPIVDAGMRQMRAEGWMHNRARLITAGYLTKHLGLDWR
                     PGLEVFFRWLLDGDRVNNSGNWQWVAGTGNDTRPYRGFNPVRQAERYDPDGAYVRRWVP
                     ELESVAGKAVHQPWRLPDGVRRTLDYPPPLEVPGTDPVWLR"
     gene            complement(13818..14918)
                     /locus_tag="MicB006_RS01225"
                     /old_locus_tag="MicB006_0248"
     CDS             complement(13818..14918)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473461.1"
                     /locus_tag="MicB006_RS01225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0248"
                     /product="serine hydrolase"
                     /protein_id="WP_116511057.1"
                     /transl_table=11
                     /translation="MHTRFTPVRDCFHDLFATGRETGASLAVWRDGVPVIDLVGGTAAT
                     VPPGAVVPASGADRAWRPDTLVDVYSTGKPVVALCLLLLVDRGRVDLDAPVSTYWPGFR
                     TPATVRQVLAHTAGLPAFPVPRPAAAIADWDLLCADLAAADPEWTPGTVAGEHAWTYGH
                     LVGELVRRVDVRPVGRFLAEEIAGPWRLDLVFGLDAADRRRCADLSYADPAWPDRMRDE
                     PGSLRARALGNPPGGTDVAMVNSDLWRAAEIPAVNLHATAAGLARLYAGLLAGGTLDGV
                     RLFSPELVAEATRVQYSGPDLLLDRPVDWTLGMQWEPDGSWGMGGIGGSSAWADPERGY
                     TFAYATARLADHDRVEELVEALHSCL"
     gene            15012..16496
                     /locus_tag="MicB006_RS01230"
                     /old_locus_tag="MicB006_0249"
     CDS             15012..16496
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283455.1"
                     /locus_tag="MicB006_RS01230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0249"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_116503281.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2.5e-46, bitscore:
                     156.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEPEQVDVVVVGLGVGGEEVAGRLAEAGLTVVGIERDLVGGECP
                     YWGCVPSKMMIRAANALAEAHRVNELAGFAQVRPDWAPVAKRIRTEATDTWDDKVAVER
                     FTGKGGRFVRGSGRLDGPNRVRVGDQVFQARYGVVLGTGTRPSVPPIDGLADTPYWTNH
                     QAIEVEELPGSLLVLGGGAIGLELAQVFARFGVRVTVIEAADRVLAVEEPEASALAADA
                     LRADGVQIHTGVRAGRVSHDGGAFTVHADGAEFTGEKLLVVTGRRAHLEELGLDTVGVD
                     AGQRYLPVNDRMHVTDGIWAVGDLTGEGAFTHIAMYQAGIVVADVLDHMRRTKGGPDAS
                     GTASVVGGAAGVVSSVGGAMSAGGSTAAPGSVPVADYRALPRVTFTDPEVGAVGLTEQQ
                     ARERGVNVQVGYADLTSSTRGWIHKTGNAGFIKLIADADQGVLVGATSAGPAGGEVLSA
                     LVVAVHAAVPISQLRHMIYAYPTFHRAIEDALRALK"
     gene            complement(16501..17265)
                     /locus_tag="MicB006_RS01235"
                     /old_locus_tag="MicB006_0250"
     CDS             complement(16501..17265)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (5-208). E-value: 2.4e-42. Score:
                     136.8. Matches aSDomain:
                     nrpspksdomains_MicB006_RS01235_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785442.1"
                     /locus_tag="MicB006_RS01235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0250"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_116503282.1"
                     /transl_table=11
                     /translation="MGVRVEHAGAVTTVILDRPEARNAVDGPTARALADAFRAFDADPD
                     AAVAVLWGAGGTFCSGADLKAVGTPRGNRVEPEGDGPMGPTRMRLSKPVIAAISGYAVA
                     GGLELALWCDLRVAESDATLGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLILTGRPVP
                     ADEAYAMGLVNRLVAPGAARAAAEELAATIARSPRTCLRNDRAAVLDGAGRPEPEAMAT
                     ELAYGTESLAIDGVRGAGRFAAGAGRHGAPTG"
     aSDomain        complement(16642..17250)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_MicB006_RS01235_ECH.1"
                     /evalue="2.40E-42"
                     /label="MicB006_RS01235_ECH.1"
                     /locus_tag="MicB006_RS01235"
                     /protein_end="208"
                     /protein_start="5"
                     /score="136.8"
                     /tool="antismash"
                     /translation="EHAGAVTTVILDRPEARNAVDGPTARALADAFRAFDADPDAAVAV
                     LWGAGGTFCSGADLKAVGTPRGNRVEPEGDGPMGPTRMRLSKPVIAAISGYAVAGGLEL
                     ALWCDLRVAESDATLGVFCRRWGVPLIDGGTVRLPRLIGESRAMDLILTGRPVPADEAY
                     AMGLVNRLVAPGAARAAAEELAATIARSPRTCLRNDRAAV"
     gene            complement(17306..17731)
                     /locus_tag="MicB006_RS01240"
                     /old_locus_tag="MicB006_0251"
     CDS             complement(17306..17731)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013970.4"
                     /locus_tag="MicB006_RS01240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0251"
                     /product="PIN domain nuclease"
                     /protein_id="WP_116503284.1"
                     /transl_table=11
                     /translation="MKLADYLIDTSALVRLLRDPDVLARWEQQVTAGLLAVCPLVELEF
                     LYTARSVADRTRLTEQLRAAFGWVVMPDRIYERAAEIQGELTARGTHRSAGAVDLLIAA
                     TAEYHGLSLLHYDRDFDQVGAVTGQPMHWLTRPDTIK"
     gene            complement(17728..17937)
                     /locus_tag="MicB006_RS01245"
                     /old_locus_tag="MicB006_0252"
     CDS             complement(17728..17937)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015619667.1"
                     /locus_tag="MicB006_RS01245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0252"
                     /product="type II toxin-antitoxin system VapB family
                     antitoxin"
                     /protein_id="WP_030500628.1"
                     /transl_table=11
                     /translation="MTKILVDVDDEALADAAEAFGTKTKKDTVNVALREGAARLRRARA
                     LAELAERGQAGDFDELLDKGAYRS"
     gene            18048..18899
                     /locus_tag="MicB006_RS01250"
                     /old_locus_tag="MicB006_0253"
     CDS             18048..18899
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785440.1"
                     /locus_tag="MicB006_RS01250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0253"
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_116503285.1"
                     /transl_table=11
                     /translation="MRELLTKIEQASGLDRVGDRLQRAVQGTLRSQRVRDALHGVWLGH
                     PLHPAMVQVPVGAWISAAVVDLLPGQRRAATALVGLGTVSAVPAAVAGLNDWASLSRDQ
                     RRIGLVHAAANTVGLALYAGSLAARLNGRHGLGRALSYLGLSAASGGAYLGGHLAYKQG
                     AQASQSVSELHLISDGWHRVGDLSSLPRHELVTKKIDEVSVILYRDGDDVTVMLERCPH
                     QSGPLGEGKVEQIDGHACVVCPWHGSAFRLNGGEVVHGPAANDQVVLPTRVVAGQVEAR
                     LP"
     gene            complement(18901..19917)
                     /locus_tag="MicB006_RS01255"
                     /old_locus_tag="MicB006_0254"
     CDS             complement(18901..19917)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473464.1"
                     /locus_tag="MicB006_RS01255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0254"
                     /product="LysM domain-containing protein"
                     /protein_id="WP_116503287.1"
                     /transl_table=11
                     /translation="MGAPRRSPVRRTGQVLTGLGALVVLVGVLAGGPVALLAFAGNPLP
                     DHLPTFAEIGTTLTSRDDGQLFLRALAVVGWFGWATFAFSVVVELLAAAVRRPAPKLPG
                     MHRQQKAAAALVGSVALILAASPAAASAAALTAPHPAVAAVTSPAVATSQVVPPAPVAA
                     ETSDPAVYRVAKGDYLGEVADRYLDDFDRYRELARLNRLADPDRIRPGQLITLPDGATD
                     SGARRHATGRLVVTKPAQTAPVKPGGGGASSTAPKAKPKPTPRDATPTVEAPVGQPPAM
                     SAGASRPTAEEGINRPLAISAVLAVASIVGAQIGALLGLRKRPVPARAGSSGRHRRD"
     gene            complement(19932..20363)
                     /locus_tag="MicB006_RS01260"
                     /old_locus_tag="MicB006_0255"
     CDS             complement(19932..20363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785438.1"
                     /locus_tag="MicB006_RS01260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0255"
                     /product="pilus assembly protein TadG-related protein"
                     /protein_id="WP_073826667.1"
                     /transl_table=11
                     /translation="MTGRREAENGRVSLFLAVAMTGVLAIIGLAYDGAGQLRTLQRADN
                     LAAEAARAGGQMIDRARAIEGGPKQIDQVAARAAVAAYLDAAGGVTDHEVDFPVVGAET
                     QIRVSVQITYSRDLLGLFGMQNTAIVSGEATARALTGPP"
     gene            complement(20360..20833)
                     /locus_tag="MicB006_RS01265"
                     /old_locus_tag="MicB006_0256"
     CDS             complement(20360..20833)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283460.1"
                     /locus_tag="MicB006_RS01265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0256"
                     /product="TadE/TadG family type IV pilus assembly protein"
                     /protein_id="WP_073826664.1"
                     /transl_table=11
                     /translation="MSAGPRRERGSVSIEVAVLAPAFIGLMVLAGVAGRTAVADEAVES
                     AAHDAARAASLARNADDGAEAAEDAARDQLGWAGLNCTGPPQIDLAGSVAGTTTSFAAA
                     YQSAAGVPATVTVTVTCTVSFDDLSAPGLPGVPGGKTVSARFTSPLDTYRSRG"
     gene            complement(20830..21312)
                     /locus_tag="MicB006_RS01270"
                     /old_locus_tag="MicB006_0257"
     CDS             complement(20830..21312)
                     /GO_process="GO:0009297 - pilus assembly [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013473467.1"
                     /locus_tag="MicB006_RS01270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0257"
                     /product="TadE family protein"
                     /protein_id="WP_073827074.1"
                     /transl_table=11
                     /translation="MPRPARTVRSRPAHAGRPAGPPGPGRIAAALRARLAEGERGANPV
                     ELAVVMPVILVMLFGSIQVAVWFVARSTALNAAQTAVNAQRTIDAGPDAGRERATSFLQ
                     QSGDWLVDWEQTGPTCVETATAVTCTVQGRSLSVIPGVSFEVTQTAHGPAERWTTG"
     gene            complement(21312..21521)
                     /locus_tag="MicB006_RS01275"
                     /old_locus_tag="MicB006_0258"
     CDS             complement(21312..21521)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013283462.1"
                     /locus_tag="MicB006_RS01275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="MicB006_0258"
                     /product="hypothetical protein"
                     /protein_id="WP_013283462.1"
                     /transl_table=11
                     /translation="MHLYAYLYVAVSTRLAELRRDSERGDSPVPTAVIIFGLVAVAMAV
                     TGLALAKANNWMNAIPNNTAPQAP"
     misc_feature    21774..21788
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.92"
                     /tool="antismash"
ORIGIN
        1 ggtggcggcc cgctggtggc ggcggagcag ctcctggagg gcggcgatct cggagtgcag
       61 ggcctgacgg gagaccggga ccggtgtgcc ttcagtcgcg gtcgaggtcg gcgagcaggg
      121 cctcgacctg ggcccggatc tcgtcgcgta cgcctcgcac cacgtccaag ggctggccgg
      181 cggggtcggt gagcttccag tcctcgtacc gtttcccggg gaagaccggg caggcgtcgc
      241 cgcagcccat ggtgacgatg acgtcgctgg cctgcgcggc gtcccaggtg aggcgggcgg
      301 gggtctaacc ggtgaggtcg atgccgacct cgcgcatggc ctcggccgcg accgggttga
      361 tccggtcggc gggctcgctt ccggcggagc ggacctcgac ggcgtcaccg gcgaggtggc
      421 gcagccaggc ggcggccatc tgggagcggc cggcgttgtg cacgcagacg aacaggacgc
      481 ttggcttgtc gctcatcgag cttcggtctc ccgggtgagg tgcggtacga ccacgtcgcc
      541 cgcggtgtcg gcggcgtgcg ggtaccagag ggcgagggcg gcgacggcga gcacgccgcc
      601 ggccagttgg gcggcgagga agccgggcac cgagccgggc gcgatgccgg cgaacgtgtc
      661 ggtgacggcc cggccgacgg tgacggcggg gttcgcgaac gaggtcgacg aggtgaacca
      721 gtaggccgcg ccgatccagg cgccgacggc ggccggcgcg gcggcggtac ggccggaccg
      781 ggcgagcgcg aagacgagga ccaccagacc ggcggtggcg accacctcgg ccagcaggag
      841 gtggcttccg ccgcgtacgg tgcgggacca ggtcgcggcc ggcaggccga acatcaggtg
      901 ggcgaggacg gctccggtga tcgcgccacc gacctgcgcc acggcgtacg cgacgaggtc
      961 cggcccggtg aggccggtgc cggcgcggcg gccgagccac cagtcgacgg cggagaccac
     1021 cgggttgagg tgtgcgccgg acaccggacc gaagatcagg atgagcgcgc ccagcgccag
     1081 cgcggtggcg atcgcgttct ccagcagttg cagcccgacg tcggacgggg agagccgggt
     1141 ggccgcgatg ccggagccga ccacggcggt aaccagcagc gccgtgccgg cgaactccgc
     1201 cgaggcgcgc cggggcaggg cgagcgtcac gagtcgtggg cggggatctg gagtagcgcg
     1261 ccgagttggc ggaacacgtc ggggcgtacc cggtaccaga cccaggtgcc gcgccgctcg
     1321 gagtcgacca gcccggcctc gcgcagcacc ttgaggtggt gcgagatggt cggtccggac
     1381 aggtcgaagg ctggggtcag gtcgcagacg cagatctccg gcaccgaggc gatcatcgac
     1441 atcaggcgca gccggatggg gtcgccgagc gccttgaaca tcggcgccac cactgccgcc
     1501 tggtccggct ccatggggcg tacggacatc ggcgggcagc aggcgaccgc gtcgaggtcc
     1561 acgatcggca gcgcttgttt cgacattcct ctaggttgac agacttcaaa acaggaggca
     1621 aggttggccc tgcttcgaca ttcatctagg cagggagttc acatgtcccg cgtccagctc
     1681 gccctgcgcg tgtccgacct cgaaggctcc gtcgccttct acagcaagct gttcggcgtc
     1741 gagccggcca agcgccgccc cggctacgcc aacttcgcgg tggagaaccc gccgctgaag
     1801 ctcgtactcc tcgaaggtga gcccggcctg ccgacggtga tggaccacct cggggtcgag
     1861 gtggccacca ccgacgaggt gaacgccgcg accaaccggc tcaccgagtc cggcctgatc
     1921 acgctggagg agaacgacac cgagtgctgc tacgcgctcc aggacaaggt ctgggtacgc
     1981 ggccccggcg acgagccgtg ggaggtctac acggtcaagg ccgactcacc gcagctggag
     2041 aaggtgaccg agagcgcctg ctgcgcctcg gacgccgccg agcagcccgc cgccgtctga
     2101 gccggacacc gcgagatcct caccggcgga cgcgccggtg aggatctctg tcgtcgttga
     2161 gccacctcag catgcccacc gcgcacgtcg actatcgcgc tttggcgaac ttcagccgtg
     2221 cgaacgcctc gacgtagacg aaccgcttgc cgtccggaga gaagctcggg tggtacgcgc
     2281 gggcgccgtt ggcgatcctc gtcttcttcc cgctgccgac gtcgaccgac cacaccccgc
     2341 ccacgtgatc cgacgcgaca gcggcgatca ccgaccggcc gtccggcgac accgccaggt
     2401 tggcgaggcc aggcagctcc gtgaggaacc tggctgtggc cgatccgacg tcccactcgg
     2461 tcaggtgcca ggtgaggtcg ttcggactca cctcgggcgg cagcggcaac ctgccgaggg
     2521 agtcgggtgc ggtgatgaag aacagccgct cacccagcgc cgcgggcgac cgcgccagca
     2581 ccgtcgaccc gcaatccgtg tcaccgccgc tggggttgaa ggtcgccccg cccaccgtca
     2641 ccggagagcc gaactcgtac gccttcccgt cggcgagtag ctggattcct cccggaccgc
     2701 acttccgggg cgcctcgaca tatccgccgc ggccaccgtt cacgagtgcg gcgtcgacga
     2761 ggaagcgcgt cgacgccaga ggctcgaacg tcttgtcggc gggcgagtag ctgagcagct
     2821 cggttccgtc ccagccgcat tcgagggcca ccccgaggtc gccgtcgggg cccgcgaaca
     2881 ggaagctgaa caggcccgct tcgcaggtgg acaccgctgg cgcgcgcgtg agaacgggtt
     2941 cctcggcgct cccatcgggt cgctgccgcc acacctcagc cactcccgaa ctcgaggtcg
     3001 aggtcacctc ccgcaggtag tagacccagc cgtcggcggc ccagaccgga tggaacaggg
     3061 agacccggtc caggagtccc gagacccggc cacacccgcc gagcaggatc accgccagta
     3121 cgaggaccgg cgccagagcc gtacgcagca cccgcacacg cgacccttcc gcctcatccc
     3181 gtccgtcact cagcgggctc accgtaggca ccgccgttgc cggggtgcgt accgtacacc
     3241 cgccaggtac tccggcgtgg cggcctgtgc cggccgtggc tcctgcccgt cggccaggaa
     3301 gcgcaacccc tagcgggacc ggaccacggc cgtgacctcg acctcgagca cagcgcccgg
     3361 caggaacagc ttgctgatct cgacagtcgt gctcgccggc ggcggtgtac ccgtgaagac
     3421 ccggcgccgg actgccgcgt acgccggcag gtcagccagg tccgtcatga acgtgcggat
     3481 gtgcagcacg tcgtcgaagc acgcgccgtg cgccgcgagc acgccgtcca cgatctcgaa
     3541 gatccgttcg gcctgggcgc cgggttctcc gggggctacc accttgccgt cgtcgtcgac
     3601 ggcgacctgt ccggcgagca tcagcagcgc gccgccgccg acatcgatcc gggcgacgtg
     3661 cgcgaagcgg tcgccgaacg gggccgcgac ggatgcgggg ttgtccaggg tgaggcgcat
     3721 cagcgtccct tcaggaagtc ggctgagacg agggaggaga gatccgcgtc ctggtccggc
     3781 gcggcctgca tcaggtcgag ggcggcctcc agcacgggag ccggcaccgg gcggcgcagc
     3841 gccagccgcg catccttcgc cgccatcgcg actgcgaacg aggcgcccgg cgctgtgacc
     3901 cgtccgaccg cgccggcaag ggccccacgg ccgaggacgt cgagggcggt ctgcctgtcg
     3961 acaccgagcg ccgcggcgac agccagcgcg tcgtgcagtg cggcgacagc cgtcaccagg
     4021 cccgtgttcg cgacgagctt gacggcggcg cctgcgccga tcggaccgca gtgacggacc
     4081 gagccgagtt gttccagcac cggagccgcc ctctccacgg cgtcggcagg gccgcccgcg
     4141 aagatcacca gcgtgccggc gtgggcggcg ttgacgctgc cgccgacggg ggcgtcgagg
     4201 agtgagacgc ccgccggcag ccggccggcc actgctcgga cttcgtccgg cccgatcgtc
     4261 gacatctgca ccacgaccgt cccgggtcgg agcgctgtgg cagcgccgtc cggcccgaac
     4321 agcaccgtct cgaccgcggc ggcgtcggcg agcatcacga cgacgacgtc ggctccgtcg
     4381 accgcggcgg acgggctcgc ggccaccgtc gcgccgaccg cggcgagcgg ctccgaacgc
     4441 tccgggctgc ggttccacac tctgacccgg ttgccaccgg ccaggaggcg gcgcgcgatc
     4501 ggcgtaccca tgtgtcctgt cccgaggacc gcgatgatct tcacgccgta acgctaggcc
     4561 ggtgaaagca atgcggccaa cgaatgtctc gcatgtctgc catgcgcgaa taccatgcct
     4621 gccatggaga ctcagctgct ggcggtgttc cgcaccgtcg cgcggcacgg ctcgatcacc
     4681 accgctgccc gcgccctccg cttcacccag tcggctgtct cccggcagat cgccgcgctc
     4741 gaggccgaca tcggcgctcg gctcttcgac cggctgcccc gtggcgtagc cctcaccgag
     4801 gagggacgag agctgctccc acacgccgag gcggtcctcg accggctcgc cgcggtccgg
     4861 cgtgaccttg aggacctgcg cgggctcggc cgagggcggc tgcgtgtggg cgccttcccg
     4921 accgctgtcg cggccctcgt accccgagcg atggcgtcgt tccgctcggc ctacccggag
     4981 atctcgctgt cgctggtcga gggtgtgacg ccgcggctgc tggagcgcct gctcgcggag
     5041 gaggcggatg tggcagtggt cagcacctct cccacgggtg agttggaccg cgaacgattc
     5101 gacctgcgac atctgctcga cgagcggctc ctggtcgcgg tcgcgcgtga ccaccggctc
     5161 gcgcgccgcc gctcggtgcg cctggcggag ctcgcccagg acgcgttcgt cgtgggctcg
     5221 gccaccgcgg agaacaccct gctccgcgca agcctgccca gcggtttctc gccacgtatc
     5281 gacatcgtcg cggccgagtg gaccggcaag ctgggatgcg ttgccgccgg cctgggggtg
     5341 gctctggttc cggccctggc ggtacgcgga accccgccgg acatcgccct gctacgcctg
     5401 catccggacg acgagtcggt acggcagata ttcgcggcga ccgtgcgggg caggacgccg
     5461 tcgccggcag tcatgcattt tcttgagcat ctgcgggcgg aggcggccca cctgggctga
     5521 ccaccttacg tcacccatgc ccggacgaca gacggcctgc cgggggaaag cagaacgccg
     5581 acctgcgtat ccgctggtcg gcgttcctgt agcccggcga aaggctatgt ggccaggggc
     5641 ggggtcgaac cgccgacctt ccgattttca gtcggacgct cgtaccaact gagctacctg
     5701 gccgtggtgc tcggcacatg ctaccgcacg agccgatacg cagaacgccg cgcattgagc
     5761 tgcgcggcgt cagcgcttgc ggtcctgacg ggacttgaac ccgcgacctc cgccttgaca
     5821 gggcggcgag cactccaact gctccacagg acctggctgg tgttgcatcc ggcgcgagcc
     5881 ggaccgtgcc cccaacggga ttcgaacccg tgctaccgcc ttgaaagggc ggcgtcctgg
     5941 gccgctagac gatgagggcg gccccgccat cattgcacac tcgcaacttc aagcggactt
     6001 gctcccatcc ggccccgccg gaggcaggag aagcatatgt catgcctgca cggacggcca
     6061 aaccggtatg ggcacggctg cggagccggg taaaaccgca ggtcaacgga ggtgtgcgat
     6121 cccgtaccgc cgtttcaggt ccgggatcag gtgccggcac gcggccatcg tctgggcccg
     6181 gtcaccgccc gcgtcgtgca tcagcacgac cgagccgtgc cgggtggcgc ctgtcacacg
     6241 cttgatgatc gtcttcgccg gtgggtggtc ccagtcctgc gggtccacgc tccagtgcag
     6301 cgggcgcagg cccatctgcc gggccaccac gatctcctcg gcggtccacc ggccgccggg
     6361 ctggcggaac caggtgatcg gcgccttggg cgcggcagcg cggatggcgt cgttggtccg
     6421 ctccaggtcg gcccggatct cggcggccga ccgccggccg aggttcacgt cgtggtgcca
     6481 gctgtggttg cagagctggt gaccctcgcg gacgatccgg gccaccagct ccgggtagcg
     6541 cttggcctgc tggccgacca cgcagaacgt ggcggtgacc cgggccgccc ggagctgggc
     6601 caggatctgc ggggtgtagc gggggtccgg cccgtcgtcg aaggtgagcg ccactccgct
     6661 gctcccgctg gcccgatgca ggcccgccgg gagcttcttg ggcaccgggc gcagcttcgg
     6721 cttcctgggg gtgggggtgg gggtcggtga aggctccgtc gcgggcgacg gcgacgccgg
     6781 gaccgacggc gaggccgccg cctgttcggg tgacttgccg gcgtcgccgc aggcggtgac
     6841 gaggagcacc aggcccaggg cgagcgccgg cagggcgcgt ggacgcattc gtcgctcccg
     6901 gaggggtcgg ggtcagacgg actttccgac cgtagtggac gcgccccgga gcggaaaggc
     6961 cgtcagcccg tggtcgactg gtccagcgag tcccgaaccg ccacggcgag tgagagcgcc
     7021 tcggccagat ccaccggccg gaccaccccg gccggcagcg agtcggcccg ccagccgggc
     7081 ccggcggcga gcaccagcag cggcctgcgc gggaccgtca gcagcgcggt gagctggcac
     7141 gggtcggcgg tcgagcgggt gtgcgaccag aggaccacgg cggccggccc ggtccggttg
     7201 accgcctcca cgagggcggg caccggcacc cgggcgccga gcatgcgaca gctcaccccg
     7261 gcctccgcga gcgcggcggc gagcgcctcc aacggcagcg agtgctgttc ctcgtcggcg
     7321 caggagagca ggatccgggg cgggccgccg ttcgggtggg cccggatcac cgtggcgaac
     7381 gccaccgaga cgcaccggga catcaggtgt tccacctcga tcaggccggc ggtggcggcg
     7441 tgccgttccc cgatgccggt gagcaccggc cggagcagcc cctcccaggt cgccaccacc
     7501 ccgtcggcgg cgagcgcgtc ggcgatggtc cgcgcgatgg tcaccgagtc caggcgcatc
     7561 gcggcgcggg ccagccctcg tgcggcgggc ccggcccggc cgaccgggat ggtcgtgccg
     7621 ccgccgtcgc gtaccgccga ggttcgtgcc ttgagcgcga gccggtccgg aggcagcacg
     7681 gccggggcct gccgggccca gcgggccgcc tcggcgggcg ccaccccctc cgcggtcagc
     7741 cggcgcatga tctccaggcg ggcgaggtcg gcgggcgtgt agcgccggtg gtggcccggc
     7801 acatgctcgc tgggaccgag gccgtagcgc tggtgccagg tgcgcagcgt ggtgaccgcc
     7861 acaccgagtc ggcgtgccac ggcccccgcg ctcagcgcct catcggccac ccgaccgctc
     7921 cggtgcctcg gaggctgcga cgcccggccg ggccgggccc gccgcaggca gcagccggtt
     7981 gaccacgccg cccagccacg gggcgtacgc ccgggggtcg gcgtccaggt cggccaccac
     8041 cgcgccgggg tcggcccacc gcaggtcggc cacctcgtcc ggatcgggcc gcgtcaccag
     8101 gtccgcgggt acgtcggcgc gcagcacgtg gtcgtactcg aactcgacgc ggccggtggc
     8161 cgggtcctcg gcgtagtaga tgtagacgcc cacctcggtg agcgcgaccg ggccgaggcc
     8221 cagttcctcg gcgagccgcc ggttggcggc ctcggtcagc gactggcccg gcagcgggtg
     8281 cccgcagcag gagttcgccc agcgcagcgg gaagcgcgtc ttcaccgcgg cccgctgctg
     8341 caacagcacc cacccctgcg ggtcgaccag gagcaccgag aaggcccggt gcagccggcc
     8401 gggtggctgg tgggcggtcg ccacggtggt ctcgccgagc acctgcccgt cgtcgccgac
     8461 cagctcgacg aggtgttcct cccgctcgct catgccgtcg ccccggtgat ccgggcggcg
     8521 gcgagcttgc cgctgatcag caccatcggt acccccacgc ccggctgcgt gccggagccg
     8581 acgaagacca cgttgtccag cttccggtgc aggttggagg ggcggaacgg gccggtctgg
     8641 aagaggctgt gcgcggcggc gaacggcgtc ccggcggcca tgccctgtgc cgcccagtcg
     8701 gcgggggtga cggcctccat cacctcgatg ccgtcgccga aaccgacgta gccgcgctcc
     8761 tcgagcgtgc ccaccagctg ttcggcgtac cgctgcgtga ggtcgcccgt ccagtcgaac
     8821 ggcgcccgct ccaggttcgg caccggcgcc agcacgtagt aggtgtgctt cccggccggc
     8881 gccaccgacg ggtcggtgcg gctcgggttc gtcaccagca gtgacgggtc ggtcatcagc
     8941 tcgcctcggc ggatcacctc gtcgaacgtg cccttccagg accgcccgaa gtgaatgttg
     9001 tggtgggcga tcttgccata gccctgcgtc gaaccgatgt gcagcaccac gcaggacggc
     9061 gagtaggtga gcttgcgctg ccggctgggc ggcagcaggt cctcgtaggc gaccggcagg
     9121 tccgggttga gcaccaccgt gtcggcgggg acgaagtcgc cgtccgcggt gatcacgccg
     9181 gtggcgcggc cgttggcggt ctccacccgg gtcaccgtgg tgccgtaccg gaactgcacg
     9241 ccgtgcttct ccgccgcgcc ggccatgccg cgcgagaccg cgtggatgcc gccgcgcggg
     9301 aagcacaccc cggccaccga gtcgaggtac gcgatgaccg tgtagatcgc cagcgcgtcg
     9361 tgcggcgaca ggcccgcgta catggcctgg aaggagaaga tccgctgggt acgcgggtcg
     9421 cggaagaact ggttgatctt cgtctggagt cgccggaagg cgccgttggc gaacagcttc
     9481 aacaggttgc cggtgagcag gtcggtcggc gcgtcgaggt tgcgctcgat gaagtcggcc
     9541 cgttcccact gccacaggtt gcgggcgtag tcgacgaaac gcaggtagcc gtcggcctcc
     9601 cgggggccgc agacgcgggc gatctcggcg gccatccggg tggtgtcggt gatgacgtcg
     9661 agcgtcgacc cgtccgggta gtaggcgcgg tacgccgggt cgagcgggct caggtcgagc
     9721 cagtcggtca gctcctcgcc caccgcgccg agcgcctcgg cgatcaggtc gggcatggtg
     9781 aggacggtcg ggccggtgtc gaactcgtac ccgtcgacgc tgagccgccc ggcgcgcccg
     9841 ccgggcaccg gctcgcgttc cagcaccgtc acctgccggc cactgccggc caggtgcagc
     9901 gcgcaggcca acccacccaa cccggccccg accactacca cccggtcggt ccgtcccttg
     9961 acggtacgca ttccggcccc cttgctcacg aagttgctca tcatgcccgc cgcgcggtgg
    10021 cggcggtggc gagacccgtc agcgcggtgc gcgcggtctc atcgatcggt gcggtgccga
    10081 gcgcggcgag cgcctcggtg acccggtcgg cgatcatccg ctccacccgg gccgtggccc
    10141 cggtgtcgcg gaccacgtcg gccagccggt ccacctcgcg tgccgtggtg accgagccgg
    10201 cccggtccag cacccggcgc tgcgccgggt cggcgagctg ccgagccagc atgagcagcg
    10261 cggtcggctt gccggtacgc aggtcgtccc cggccggttt gccggtggtc tccgggtcgc
    10321 cgtagacgcc gaggaggtcg tcgcggagct ggaacgcctc gccgacggcc agcccgtacc
    10381 gggtgtacgc ggcgatgagc gggtcgtccg cgtcggtgcc ggccaggcag gcgccgaaga
    10441 gcagcggccg ctggacggtg tagctggcgg tcttgtaccg ggccacccgc agcgcccggt
    10501 cgacagtcca gttccccgcg tcgttctcgc cgagcacgtc caggaactgc ccggcgaccg
    10561 tctccacgcg catctggtcg tagcagcggc gcacgtcgag cagccgctcg gcggggaccg
    10621 ccgcgtggct catgagccgg tcggcccaca ccatgcagag gtcgccgatg aggacggcga
    10681 ctgcttcgcc gtaccggtcg gggtcgcccg agtgcccggc ggcccggtgc cgggcagcgg
    10741 cggcccggtg cgcggtcggc agtccgcgcc gggtgtcgga ggcgtccatc acgtcgtcgt
    10801 gcacgagcgc gaacgtgtgc agcagttcga gggcggacag ggccgggagc accgaacaca
    10861 tcggttcctc cccgccgacc gcaccccgcc atccccagta cgcgaacgtg gggcggaccc
    10921 gcttgccgcc ggccagcacg cagtcgcgcg cggtcgcggc gaaagcaccc atcgctgcgt
    10981 cgatctcggt gagcgagtcg acttccgcgg ccaggaacgc caccagcgtc tcatcgaccc
    11041 ctttgatcag gtccttcgtg aacgcggcca gtacgccgcg gaccggatcg tccgtcgccc
    11101 cgggctgagc cggcgcgacg cggagcgcat tacccgcaac tgcgtcgttg gccatgtggg
    11161 cgagcgtacc ctagggttac gagttgcgtc gattgatgcg tcgaaactga ggagggccga
    11221 tggacgtgga tctggccgcc gcctatgacc gttgccgcga gctgcaccgg cgtcacggcc
    11281 gtacctacta tctcgccacc cggctgctcc ccgcctggaa acggcggcat gtgcacgcct
    11341 tgtacgggtt cactcgctac gcggacgaga tcgtcgaccg caccgaggac ctgccgcccg
    11401 ccgagcgcgc ggcccggctg cgcgagtggt cggatcgatt cgtggccggg ctgcacggcg
    11461 cgtcggtcga cgacccgctg ctccccgccg tgctgcacac catcgccgtg ttcgacctcg
    11521 accgggacga cttcgcgtcg ttcctgcgca gcatggcgat ggacctgacg gtcatgtcgt
    11581 acccgaccta cgacgacctg ctcgactaca tggagggctc ggcggccgtc atcggcacca
    11641 tgatgctgcc gatcctgggc agctccgatc cggccgccgc ccgggagccc gcccgccagc
    11701 tcggcttcgc gttccagctc accaacttca tccgggacgt cgccgaggac ctcgaccggg
    11761 gccggaccta cctgcccgac gaggatctgg ccaagttcga cgtcacccgc gccgacctgg
    11821 tcgcggccaa ggacgccggt cgcaccacgc cgcgcatccg tgagctgatc gagtacgagg
    11881 tgacccgcgc gcaggcccac tacctcgccg ccgcgccggg catcccgctg ctcaaccccg
    11941 cctcgcaggc gtgcatgcgc accgcgtacg cgctctacgg cggcatcctg gacgaggtcg
    12001 ccgcgcagga ctacgacgtc ttcgtccgcc gggccctggt gccgcagcgg cgccggatgg
    12061 cggtggccgc gcgggcgctg ctcaccccgg ccggcacgcc ggtgcgggtg cccggcccgg
    12121 cgctggaacc ggccctggcc ggatgaccgg ccggacggcg gtcgtgctgt tcacccgcga
    12181 cctgcgggtg cacgaccacc cggcactggc cgccgcctgc tccgcgttcg agcgggtggt
    12241 gccgctctac gtgctagacc cggcgttgca gaagctctcg gcgaaccgca cccggttcct
    12301 gcaccagagc ctggccgacc tgcgcgaggc gctgcgcgcg ctcggcggcg acctggtggt
    12361 gcggcgcggc gacccggtga ccgagacggt cgagctggcc cggaaggtgg gtgccgaggg
    12421 cgtcgggctc tccgccgacg tcagccgcta cgcccgccgc cgggaacgtc gcctgcgcgc
    12481 cgagtgcgac cggcaccgca tgttcctgcg gctgttcccc ggcctgacga tcgtcgagcc
    12541 gggagcgctg cgacccagcg gcggcgatca ctatcgcgtg ttcagcccct acttccgcgc
    12601 gtggcagggc gtgcgcccgc gggacgaact cgccgcgccg aagcgggtcc ggctgcccga
    12661 cggcgtcgac ccgggtcgtc tgcccgaccc gccgaagggc gacagcccgg ccgccgccgc
    12721 gggcggggag agcgtcgccc gccgccggct caccgcctgg ctgcccaccc tcgaccggta
    12781 cgacgacatc cacgacgaca tggccggtga cgagacctcc cggctcagcc cgtacctgcg
    12841 cttcggctgc gtatcgccgc tgaccgtggc gaaccgggcc ggtgaccggg acgggccgtt
    12901 cgtccggcag ctctgctggc gcgacttcta ccaccaggtc gtcgccggtt tccccgacct
    12961 gtccactact gcctaccggc gcggcgcccg ggaggactgg cggtacgacg agcacgcgct
    13021 cgacgcctgg accgagggac ggaccggcat gccgatcgtc gacgccggca tgcgtcagat
    13081 gcgcgccgag ggctggatgc acaaccgggc ccgcctgatc accgccggct acctgaccaa
    13141 gcacctcggg ctggactggc ggcccggcct ggaggtgttc ttccggtggc tgctcgacgg
    13201 cgaccgggtc aacaactcgg gcaactggca gtgggtggcc ggcaccggca acgacacccg
    13261 gccgtaccgc ggcttcaacc cggtacggca ggccgagcgt tacgaccccg acggcgcgta
    13321 cgtgcggcgg tgggttccgg agttggagtc ggtggcgggc aaggcggtgc accagccgtg
    13381 gcggctgccc gacggggtgc gccgcacgct cgactacccg ccgccgctgg aggtgccggg
    13441 caccgacccg gtctggctcc gctgacgccc ttcgtcgccc gtcgcccgtc gcccgagcgt
    13501 cctcacgagc atcaacgtcg ctggcgcaga gcccacgcgg atcgcgaggc cactgctctc
    13561 atagttactg caagtgactg cggctctcgc ccgtagcatc cacctccggt cgactttgct
    13621 ctgcagccat atccgcaccc gttgcggaaa gtgaccgcgc gcgcccctcg cggttttcgg
    13681 acctattgtg aatgccctgc tcaacgcggt gctgcgccat tggctgcaga gcaaagtcga
    13741 aaacggaaga ccaagtggtc ccgccggccg aatgcgctgc gtgacgaggc actggaatca
    13801 cagaaagtga ctcacggtca gaggcaggag tgcagcgcct cgaccagctc ctccacccga
    13861 tcgtggtcgg ccagccgggc ggtcgcgtac gcgaaggtgt agccccgctc cgggtcggcc
    13921 caggcgctgc tgccgccgat tccgcccatg ccccagctgc cgtccggctc ccactgcatg
    13981 ccgagcgtcc agtccaccgg ccggtccagc agcaggtccg gtccgctgta ctgcacccgc
    14041 gtcgcctcgg cgaccagctc cgggctgaac aggcgtaccc cgtccagcgt gccgccggcg
    14101 agcaggcccg cgtacaggcg ggcgagcccg gcggcggtgg cgtgcaggtt caccgccggg
    14161 atctcggcgg cccgccacag gtcgctgttc accatcgcga catcagtccc gccgggcggg
    14221 ttgcccagcg cccgcgcccg cagcgagccc ggctcgtcgc gcatccggtc cggccaggcc
    14281 ggatcggcgt acgacaggtc ggcgcaccgc cgccggtccg ccgcgtccag cccgaagacc
    14341 aggtccaggc gccacggacc ggcgatctcc tcggccagga accggcccac cggccgcacg
    14401 tccacccggc ggaccaactc gcccaccaga tgcccgtacg tccaggcgtg ctcgcccgcg
    14461 acggtgcccg gcgtccactc cgggtcggcc gccgccaggt cggcgcagag caggtcccag
    14521 tcggcgatcg ccgcggcggg ccggggcacc gggaaggcgg gcagcccggc cgtgtgggcg
    14581 agcacctgcc gcacggtggc cggggtgcgg aaccccggcc agtacgtcga caccggcgcg
    14641 tcaaggtcga cgcggcccct gtcgacgagc agcagcaggc agagcgccac caccggcttg
    14701 ccggtcgagt agacgtccac gagcgtgtcc ggccgccacg cgcggtctgc cccggaagcc
    14761 ggtacgaccg cgccgggcgg gaccgtcgcc gccgtgccgc ccaccaggtc gatcaccggt
    14821 acgccgtcgc gccacaccgc cagcgacgcg cccgtctccc ggccggtggc gaacaggtcg
    14881 tggaagcagt cccggaccgg ggtgaagcgc gtgtgcatgc gggccacggt aggcggtcgc
    14941 gtcggttacc ggcgcgggaa ttcaggcccg gcgcggtggc cggtgtcccg aaggtgcgga
    15001 atgcttgcgg aatggcggag ccggaacagg tggacgtagt agtggtcggg ctcggcgtcg
    15061 gcggcgagga ggtggccggg cggctcgccg aggccggcct cacagtggtc ggcatcgaac
    15121 gggacctggt cgggggcgag tgcccgtact gggggtgcgt gccgagcaag atgatgatcc
    15181 gggcggcgaa cgcgctggcc gaggcgcacc gcgtcaacga gcttgccggt ttcgcccagg
    15241 tgcggcccga ctgggcgccg gtggcgaagc ggatccggac cgaggccacc gacacctggg
    15301 acgacaaggt ggcggtggag cggttcaccg gcaagggcgg ccggttcgtc cggggcagcg
    15361 ggcggctcga cggcccgaac cgggtacgcg tcggcgacca ggtgttccag gcccggtacg
    15421 gcgtggtcct cggcaccggc acccggccct cggtcccgcc gatcgacggg ctggccgaca
    15481 cgccgtactg gacgaatcac caggccatcg aggtcgagga gctgcccggg tcgctgctgg
    15541 tgctcggcgg cggcgcgatt gggctggaac tggcccaggt cttcgcccgg ttcggcgtcc
    15601 gggtgacggt catcgaggcg gccgaccggg tgctggccgt cgaggagccg gaggcgtccg
    15661 cgctcgccgc cgacgcgctg cgcgccgacg gcgtgcagat ccacaccggg gtccgggccg
    15721 gccgggtcag ccacgacggc ggcgcgttca cagtgcacgc cgacggcgcc gagttcaccg
    15781 gcgagaagct gctcgtggtg accggccgca gggcgcacct ggaggagctg ggcctggaca
    15841 ccgtcggggt ggacgccggg cagcgttacc tgccggtgaa cgaccggatg cacgtcaccg
    15901 acggaatctg ggcggtcggc gacctcaccg gcgagggcgc gttcacccac atcgccatgt
    15961 accaggccgg catcgtggtg gcggacgtgc tcgaccacat gcggcgtacc aagggcggcc
    16021 cggacgccag cggcaccgcg agcgtggtcg gcggcgcggc cggtgtggtc agctcggtcg
    16081 gcggcgcgat gagcgcgggc gggtcgacgg ccgcgcccgg cagcgtcccg gtcgccgact
    16141 accgggcgct gccccgcgtc acgttcaccg accccgaggt cggcgcggtc ggcctcaccg
    16201 agcagcaggc ccgcgaacgc ggtgtcaacg tccaggtcgg atacgccgac ctcacctcgt
    16261 cgacccgcgg ctggatccac aagaccggca acgccgggtt catcaagctg atcgccgacg
    16321 ccgaccaggg cgtgctcgtc ggcgccacct cggccggacc ggccggcggc gaggtgcttt
    16381 ccgcgctggt cgtggcggtg cacgcggcag tgccgatcag ccagctccgg cacatgatct
    16441 acgcgtaccc cacgttccac agggccatcg aggacgcgtt gcgcgccctg aagtgacgcc
    16501 tcagccggtc ggcgccccgt gccggccggc cccggcggcg aaccggccgg caccgcgtac
    16561 cccgtcgatt gccagcgact ccgtgccgta ggccagctcg gtcgccatcg cctccggctc
    16621 cggccggccc gcgccgtcca gcaccgccgc ccggtcgttg cgcaggcacg tccgcggaga
    16681 ccgggcgatc gtggcggcca gttcctcggc cgccgcgcgg gccgcacccg gcgcgaccag
    16741 ccggttgacc agacccatcg cgtacgcctc gtcggccggc accggacggc cggtgaggat
    16801 caggtccatc gcccggctct cgccgatcag ccggggcagc cggaccgtcc cgccgtcgat
    16861 cagcggtacg ccccaccggc ggcagaacac gccgagcgtc gcgtccgact cggcgacccg
    16921 cagatcgcac cagagcgcca gctccaggcc gccggccacc gcgtacccgg agatcgcggc
    16981 gatcaccggc ttggacagcc gcatccgggt ggggcccatc ggcccgtccc cctcgggctc
    17041 gacccggttg ccgcgtggcg tgccgacggc cttcaggtcg gcgccggagc agaacgtgcc
    17101 gcccgcgccc cagagcacgg cgaccgccgc gtccgggtcg gcgtcgaacg cgcggaacgc
    17161 gtcggcgagc gcccgggcgg tcggcccgtc cacggcgtta cgggcctcgg gccggtccag
    17221 gatcacagtg gtcacggcac cggcgtgctc gacgcgtacc cccatgggcc cagcatgccc
    17281 gcgacggcgc tgccgcggct acggcctatt tgatcgtgtc gggtcgggtc agccagtgca
    17341 tcggctggcc ggtgacggcg ccgacctggt cgaagtcccg gtcgtagtgc agcagcgaga
    17401 ggccgtggta ttcggcggtg gcggcgatga gcaggtcgac ggcgcccgcc gagcggtgcg
    17461 tgccccgcgc ggtcagctcg ccctggatct cggcggcgcg ctcgtagatc cggtccggca
    17521 tgaccaccca gccgaaggcg gcccggagct gctcggtcag gcgcgtccgg tcggcgaccg
    17581 accgggcggt gtagaggaat tccagctcga caagcgggca cacggcgagc aggcccgctg
    17641 tcacctgttg ttcccagcga gccagcacgt cgggatcacg caggagccgg acgagggcgc
    17701 tggtgtcgat caggtagtcg gccagtttca cgagcggtag gcgcccttgt cgagcagttc
    17761 gtcgaagtca ccggcctgcc cgcgttcggc cagctccgcc agcgcccggg cgcggcgcag
    17821 tctcgccgcg ccctcgcgga gagcgacgtt caccgtgtcc ttcttggtct tcgtgccgaa
    17881 cgcctcggcg gcatccgcca gcgcctcgtc gtcgacgtcc accaggatct tggtcatcgc
    17941 ggctccctat atacgactag ccgtccgagt atatccagcg gggaggccgt gcgagggaat
    18001 tccggggcgt ccggtttggg cgctctcctg ccgggaagtc ggaacgggtg cgcgaactac
    18061 tgacgaagat cgaacaggcc agcggcctcg accgggtggg tgaccggttg cagcgcgccg
    18121 tccagggcac gctgcgttcc cagcgggtac gcgacgcgct gcacggcgtg tggctcggcc
    18181 atccgctgca ccccgcgatg gtgcaggtgc cggtcggcgc gtggatctcc gccgccgtgg
    18241 tggacctgct gccgggccag cgccgggccg ccaccgcgct ggtgggcctc ggcacggtca
    18301 gcgcggtgcc cgcggcggtc gccgggctca acgactgggc ctcgctctcc cgcgaccagc
    18361 gccggatcgg gctggtgcac gccgccgcca acacggtcgg cctggcgctg tacgccggct
    18421 cgctggcggc ccgcctcaac gggcggcacg ggctcggtcg ggcgctgtcc tacctgggtc
    18481 tgtccgccgc gagcggcggc gcgtacctgg gcgggcacct cgcgtacaag cagggcgccc
    18541 aggccagcca gagcgtctcc gagctgcacc tgatcagcga cgggtggcac cgggtcggcg
    18601 acctgagcag cctgccccgg cacgagctgg tcaccaagaa gatcgacgag gtctcggtga
    18661 tcctctaccg ggacggcgac gacgtcacgg tgatgctgga gcgctgcccg caccagagcg
    18721 gcccgctcgg cgagggcaag gtggagcaga tcgacggtca cgcctgcgtg gtctgcccct
    18781 ggcacggcag cgcgttccgg ctcaacggcg gcgaggtcgt gcacggcccg gccgcgaacg
    18841 accaggtcgt gctccccacc cgtgtggtgg ccggccaggt cgaggcccgg ctgccctgac
    18901 tcagtcccgc cggtgccgcc cgctggaccc cgcgcgggcg ggcaccggcc gcttgcgcaa
    18961 cccgagcagc gcgccgatct gcgcgcccac gatgctcgcg accgccagca ccgccgagat
    19021 ggcgagcgga cggttgatgc cctcctcggc ggtgggccgg gacgcgcccg ccgacatggc
    19081 cggcggctga ccgaccggcg cctccacggt gggcgtcgcg tcccgcgggg tgggcttcgg
    19141 cttcgccttc ggcgcggtcg aggacgcgcc gccgccaccc ggcttgaccg gcgcggtctg
    19201 ggccggcttg gtgaccacca gccgcccggt ggcgtgccgc cgggcgccgg agtccgtcgc
    19261 gccgtccggc agtgtgatga gctgacccgg gcggatccgg tccgggtcgg cgagccggtt
    19321 cagccgggcc agctcccggt atctgtcgaa gtcgtccagg tagcggtcgg ccacctcgcc
    19381 caggtagtcg cccttggcga cccggtacac cgccgggtcg ctggtctccg ccgcgacagg
    19441 ggccggtggc acgacctggc tcgtggccac ggccggtgag gtgacggcgg cgaccgccgg
    19501 gtgcggcgcg gtgagcgcgg cggcgctcgc cgcggccggg ctcgcggcca ggatcagcgc
    19561 gaccgaaccg acgagcgcgg cggccgcctt ctgctggcgg tgcatgccgg gcagcttcgg
    19621 cgccggccgg cgtaccgccg ccgcgagcag ttccaccacg acggagaacg cgaacgtggc
    19681 ccagccgaac cagcccacca ccgccagcgc ccgcaggaag agctgaccgt cgtcgcggct
    19741 ggtcaacgtc gtaccgatct cggcgaacgt gggtaggtga tccggcagcg ggttgccggc
    19801 gaacgccagc aacgcgaccg gcccgccggc cagcacgccg acgagcacga cgagtgcgcc
    19861 gagcccggtg aggacctggc cggtgcggcg gacgggggag cgtcggggtg cgcccatggc
    19921 ggccttcctt cctacggtgg tccggtgagc gcccgagcgg tggcctcacc ggagacgatg
    19981 gcggtgttct gcatgccgaa cagacccagc aggtcccggc tgtaggtgat ctgcacgctc
    20041 acccggatct gggtctcggc gccgaccacg gggaagtcga cctcgtggtc ggtgaccccg
    20101 cccgcggcgt cgaggtaggc ggcgaccgcg gcgcgggcgg cgacctggtc gatctgcttc
    20161 gggccgccct cgatggcccg cgcgcggtcg atcatctggc cgcccgcgcg cgccgcctcg
    20221 gcggccaggt tgtccgcgcg ctggagcgtg cgtagttgac cggcgccgtc gtaggcaagg
    20281 ccgatgatcg ccagcacgcc tgtcatcgcc acggccagga agaggctcac ccggccgttc
    20341 tccgcctccc gccgcccggt catccgcgac tccggtaggt gtccagcggc gaggtgaagc
    20401 gcgccgagac ggtcttgccg cccggcaccc cgggcaggcc gggcgcgctc aggtcgtcga
    20461 aggagacggt gcaggtgaca gtgaccgtca ccgtcgcggg aacgcctgcg gcgctctggt
    20521 aggcggcggc gaagctcgtc gtcgtaccgg ccaccgagcc cgcgagatcg atctggggtg
    20581 ggccggtgca gttcagtccc gcccagccga gctgatcccg ggccgcgtcc tcggcggcct
    20641 ccgcgccgtc gtcggcgttg cgggcgagcg aggcggcccg ggcggcgtcg tgagcggccg
    20701 actccaccgc ctcgtccgcg acagcggtcc gcccggcgac cccggccagc accatcagcc
    20761 cgatgaaggc gggcgcgagc accgccacct cgatcgagac ggaaccccgc tcccgccgcg
    20821 gcccggcgct catccggtgg tccagcgttc ggccgggccg tgcgcggtct gcgtgacctc
    20881 gaacgagacg cccgggatga ccgacaggga gcgtccctgc accgtgcagg tgactgcggt
    20941 ggcggtctcg acgcaggtcg gtccggtctg ctcccagtcg accagccagt cgccggactg
    21001 ttgcaggaag ctggtcgccc gctcccggcc ggcgtccggc ccggcgtcga tcgtgcgctg
    21061 ggcgttcaca gcggtctgcg cggcgttgag cgctgtggac cgggccacga accagacggc
    21121 gacctggatc gagccgaaca gcatcaccag gatcaccggc atcaccacgg ccagctcgac
    21181 cgggttggcg ccccgctcgc cctcggccag gcgggcgcgc agggcggcgg cgatccgccc
    21241 cggaccgggc gggccggcgg gccggccggc gtgcgccggc cggctccgga ccgtacgggc
    21301 ggggcgcggc atcacggggc ctgcggcgcc gtgttgttcg ggatggcgtt catccagttg
    21361 ttcgccttgg ccagggcgag gccggtgacc gccatggcca ccgcgaccag gccgaagatg
    21421 atcaccgcgg tcggcaccgg gctgtcgccg cgctcggagt cccggcgcaa ctcggcgagg
    21481 cgggtgctca ccgccacgta caggtaggcg tagaggtgca tggtcgtctc cttctcgaag
    21541 gtgggttcac agacgggcga ggaacggata gacggcgaag ccgagcagga cgaacaccag
    21601 cagcgagccg gggatgtcca acttgctggt gaccccctcg gcccgggcca ggttgtcggt
    21661 acggatctgg tcgcgcagcg agtcggcacg ggaccgcaac gtctcgtgca cctgggcgcc
    21721 ctcactgccg gaggagcgca tgatggcgcc cacgtcgccc agctccggga tgccgatccg
    21781 gtcggccagc tcctgcaact cgtcccaggg cgagtgcatc tggagctggg cgagccgcag
    21841 cgcctcccgg atccggtcga agacccagcc gtcgcagacc gccgccgcgc gttccagcga
    21901 ctgcaccggg ccgtgcgcgg cggacagctg caacgccacc aggtcgaggt aggtgcagac
    21961 cgcctgccgg aactcgtccc gggcggcgtc ggccttggcc aggaccgcgc ggtgcgcgag
    22021 cagaccggcg cccagcgcca ggcccaggct ggtcagcacc ggtacggcca ccggcagcgc
    22081 caccccgccg acgaagagca ctgccgaggc gaccgccggg gtggcgaacc cgacgagcgc
    22141 ggagag
//
