LOCUS       NZ_NMOM01000013        23317 bp    DNA     linear   CON 22-JUN-2024
DEFINITION  Bacillus subtilis strain PT26A contig_13, whole genome shotgun
            sequence.
ACCESSION   NZ_NMOM01000013
VERSION     NZ_NMOM01000013.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus subtilis
  ORGANISM  Bacillus subtilis
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 800124)
  AUTHORS   Li,J., Zhang,Y. and Wang,N.
  TITLE     Bacillus subtilis PT26A genome
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 800124)
  AUTHORS   Li,J., Zhang,Y. and Wang,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUN-2017) Microbiology and Cell Science, Citrus
            Research and Education Center, University of Florida, 700 Experiment
            Station Road, Lake Alfred, FL 33850, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2015
            Assembly Method                   :: CLC NGS Cell v. 6
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 170.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003399995.1-RS_2024_06_22
            Annotation Date                   :: 06/22/2024 02:15:45
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,652
            CDSs (total)                      :: 4,563
            Genes (coding)                    :: 4,421
            CDSs (with protein)               :: 4,421
            Genes (RNA)                       :: 89
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 81
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 142
            CDSs (without protein)            :: 142
            Pseudo Genes (ambiguous residues) :: 0 of 142
            Pseudo Genes (frameshifted)       :: 77 of 142
            Pseudo Genes (incomplete)         :: 71 of 142
            Pseudo Genes (internal stop)      :: 30 of 142
            Pseudo Genes (multiple problems)  :: 33 of 142
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:54:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 776807
            Orig. end                         :: 800124
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            NMOM01000013.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23317
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="4"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..23317
                     /SMILES="NC(CCC(=O)O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23317
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[20000:>23317](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..>23317
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            221..1114
                     /gene="proC"
                     /locus_tag="CFI07_RS22015"
     CDS             221..1114
                     /EC_number="1.5.1.2"
                     /GO_function="GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /function="16.11: Scavenge (Catabolism)"
                     /function="16.2: Construct biomass (Anabolism)"
                     /gene="proC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389730.2"
                     /locus_tag="CFI07_RS22015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="WP_010886524.1"
                     /transl_table=11
                     /translation="MRTKKRTKEMLPIFDQKKVAFIGAGSMAEGMISGIVRANKIPKQN
                     ICVTNRSNTERLTELELQYGIKGALPNQLCIEDMDVLILAMKPKDAENALSSLKSRIQP
                     HQLILSVLAGITTSFIEQSLLNEQPVVRVMPNTSSMIGASATAIALGKYVSEDLKKLAE
                     ALLGCMGEVYTIQENQMDIFTGIAGSGPAYFYYLMEFIEKTGEEAGLDKQLSRSIGAQT
                     LLGAAKMLMETGEHPEILRDNITSPNGTTAAGLQALKKSGGGEAISQAIKHAAKRSKEI
                     SEDIEKTAAPLSGVIK"
     gene            1111..2226
                     /gene="proB"
                     /locus_tag="CFI07_RS22020"
     CDS             1111..2226
                     /EC_number="2.7.2.11"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004349 - glutamate 5-kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389729.1"
                     /locus_tag="CFI07_RS22020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamate 5-kinase"
                     /protein_id="WP_015714042.1"
                     /transl_table=11
                     /translation="MTPDTSMKRVVVKIGSSSLTSLHGEISIRKLEALVDQVVKLKDAG
                     YEVILVSSGAVAAGYRKLGFIQRPEKLPEKQASASIGQGLLMEAYSKLFLAHGYVASQI
                     LITRSDFSDEYRYNNVRNTMNVLLERGIIPIINENDTVTVNRLKFGDNDTLAAKVAGLI
                     DADMLVILSDIDGLYDGNPRTNPEAKRIQRVSEITPDIEACAGDTGSIVGTGGMRSKLD
                     AFKIVMASGIKGFLGQADVGDILYHAVHEQAEGTYFEAEGTLPLNQKEQWIAFNSGPEG
                     EMILSDDCSRKITNGQSSLYLDGVQKIKGKFKSGSVVRLMDSKGTEIGLGIVNYSSVQL
                     QEPEKNKELTNRALIDQEAFVCHVDFSLPVN"
     gene            complement(2278..3180)
                     /gene="gltC"
                     /locus_tag="CFI07_RS22025"
     CDS             complement(2278..3180)
                     /codon_start=1
                     /gene="gltC"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389728.2"
                     /locus_tag="CFI07_RS22025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamate biosynthesis transcriptional regulator
                     GltC"
                     /protein_id="WP_004399246.1"
                     /transl_table=11
                     /translation="MELRQLRYFMEVAEREHVSEAADHLHVAQSAISRQIANLEEELNV
                     TLFEREGRNIKLTPIGKEFLIHVKTAMKAIDYAKEQIDEYLDPHRGTVKIGFPTSLASQ
                     LLPTVISAFKEEYPHVEFLLRQGSYKFLIEAVRNRDIDLALLGPVPTNFSDITGKILFT
                     EKIYALVPLNHPLAKQKTVHLIDLRNDQFVLFPEGFVLREMAIDTCKQAGFAPLVSTEG
                     EDLDAIKGLVSAGMGVTLLPESTFAETTPRFTVKIPIEFPQVKRTVGIIKPKNRELAPS
                     ANDFYEFVIQFFSKLEQYQ"
     misc_feature    3200..3214
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: medium, score: 22.93"
                     /tool="antismash"
     gene            3327..7889
                     /gene="gltB"
                     /locus_tag="CFI07_RS22030"
     CDS             3327..7889
                     /EC_number="1.4.1.13"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0015930 - glutamate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="gltB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389727.2"
                     /locus_tag="CFI07_RS22030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamate synthase large subunit"
                     /protein_id="WP_116316679.1"
                     /transl_table=11
                     /translation="MTYNQMPKAQGLYRPEFEHDACGIGLYAHLKGKQTHAIVKQGLKM
                     LCQLDHRGGQGSDPDTGDGAGLLVQIPDAFFRKECKDINLPEKERYGVGMVFFSQKEDE
                     RKKIEKQINALIEQEGQVVLGWRTVPVNVGKIGTVAQKSCPFVRQVFIGANSDLKDNLS
                     FERKLYVIRKQAENWGVTEGLDFYFASLSSQTIVYKGLLTPEQVDAFYSDLQDEAFVSA
                     FALVHSRFSTNTFPTWERAHPNRYLVHNGEINTLRGNINWMRAREQQFVSESFGEDLNK
                     ILPILNADGSDSSILDNAFEFFVMAGRKPAHTAMMLIPEPWTENTHMSKEKRAFYEYHS
                     SLMEPWDGPTAISFTDGKQIGAILDRNGLRPARYYVTKDDYIIFSSEVGVIEVEQENVL
                     YKNRLEPGKMLLIDLEEGRIISDEEVKTQIATEYPYQKWLEEELVQVNPDPESREEEQF
                     SDLLTRQKAFGYTYEDIQKYLIPVIKEGKDPLGSMGNDAPLAVLSDRAQSLFNYFKQLF
                     AQVTNPPIDAIREQLVTSTMTWLGAEGDLLHPSERNVRRIKLYTPVLSNEQFYALKTIV
                     HPDLKSQKIDVLFSEDLERGLKDMFTQAEKAISQGVSLLILSDKKMNERLTPIPPLLAV
                     SALHQHLIRKGLRTKVSIIVESGEAREVHHFAALIGYGADAINPYLAYATYKQEIDEGR
                     LDISYEEAVSKYGKSITEGVVKVMSKMGISTVQSYRGAQIFEAVGISRDVIDRYFTGTA
                     SQLGGIDLQTIAEEAQRRHREAYQDDYSKTLEPGSDFQWRNGGEHHAFNPKTIHTLQWA
                     CRRNDYNLFKQYTKAADEERIGFLRNLFAFDGNRKPLKLEEVESAQSIVKRFKTGAMSF
                     GSLSKEAHEALAIAMNRLGGKSNSGEGGEDPKRFVPDENGDDRRSAIKQIASGRFGVKS
                     HYLVNADELQIKMAQGAKPGEGGQLPGNKVYPWVADVRGSTPGVGLISPPPHHDIYSIE
                     DLAQLIHDLKNANRDARISVKLVSKAGVGTIAAGVAKATADVIVISGYDGGTGASPKTS
                     IKHTGLPWELGLAEAHQTLMLNGLRDRVVLETDGKLMTGRDVVMAALLGAEEFGFATAP
                     LVVLGCVMMRACHLDTCPVGVATQNPELRKKFMGDPDHIVNYMLFIAEEVREYMAALGF
                     KTFDEMIGRTDVLHVSERAKGHWKASQLDLSTLLYQPEGVRTFRSPQNHKIDQSLDITT
                     ILPAVQEAIESGKEADISIEINNTNRVAGTITGSEISKRYGEEGLPEDTIKLHFTGSAG
                     QSFGAFVPKGMTLYLDGDSNDYVGKGLSGGKIIVKSPEGFNSASDDNVIIGNVAFYGAT
                     SGEAYINGRAGERFAVRNSGVNVVVEGIGDHGCEYMTGGSVVVLGDVGKNFAAGMSGGI
                     AYVLAEDVKAFKRKCNLEMILFESLEDEKEIQQIKAMLERHTAYTNSQKAEDLLDQWED
                     SVKKFVKVIPKNYKQMLASIEEQKAAGLSDEEAIMFAFEANTKPKQNTAASGQKQAVVQ
                     "
     gene            7906..9387
                     /gene="gltD"
                     /locus_tag="CFI07_RS22035"
     CDS             7906..9387
                     /EC_number="1.4.1.-"
                     /GO_component="GO:0009342 - glutamate synthase complex
                     (NADPH) [Evidence IEA]"
                     /GO_function="GO:0045181 - glutamate synthase activity,
                     NAD(P)H as acceptor [Evidence IEA]"
                     /GO_process="GO:0006537 - glutamate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="gltD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389726.2"
                     /locus_tag="CFI07_RS22035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glutamate synthase small subunit"
                     /protein_id="WP_116316680.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 2e-27, bitscore:
                     91.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKPTGFMEIKREKPAERDPLTRLKDWKEYSAPFSEEASKRQGAR
                     CMDCGTPFCQIGADINGFTSGCPIYNLIPEWNDLVYRGRWKEALERLLKTNNFPEFTGR
                     VCPAPCEGSCTLAISDPAVSIKNIERTIIDKGFENGWIQPRIPKKRTGKKVAIVGSGPA
                     GLASADQLNQAGHSVTVFERADRAGGLLTYGIPNMKLEKGIVERRIKLLTQEGIDFVTN
                     TEIGVDITADELKEQFDAVVLCTGAQKQRDLLIEGRDSKGVHYAMDYLTLATKSYLDSN
                     FKDKQFIDAKGKDVIVIGGGDTGADCVATALRQKAKSVHQFGKHPKLPPARTNDNMWPE
                     QPHVFTLEYAYEEAEAKFGRDPREYSIQTTKMVADKNGKLKELHTIQMEKVKNEHGKYE
                     FRELPGTEKVWPAQLVFIAIGFEGTEQPLLKQFGVDSVNNKISAAYGDYQTNIDGVFAA
                     GDARRGQSLIVWAINEGREVAREVDRYLMGSSVLP"
     misc_feature    7924..7937
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            complement(9444..10433)
                     /gene="yogA"
                     /locus_tag="CFI07_RS22040"
     CDS             complement(9444..10433)
                     /NRPS_PKS="Domain: PKS_ER (15-324). E-value: 1.5e-39.
                     Score: 127.9. Matches aSDomain:
                     nrpspksdomains_CFI07_RS22040_PKS_ER.1"
                     /codon_start=1
                     /gene="yogA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389725.1"
                     /locus_tag="CFI07_RS22040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_014479971.1"
                     /sec_met_domain="ADH_N (E-value: 9e-13, bitscore: 43.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.1e-28, bitscore:
                     94.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVIHNGKAGLLGLSVQDVPSTKPGYGEVKVKLKSAGLNHRDLF
                     LMKNKSEQDPHMILGSDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEIL
                     GGPSDGTLAEYVIIPSQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLI
                     PGIGSGVATYALFMAKAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKA
                     DVVLDSIGPALFSEYFRHVKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGE
                     EFQAMLAFIDKHKLRPVIDRIYPLEKACEAYKRMQEGRQFGNIGIVME"
     aSDomain        complement(9462..10388)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CFI07_RS22040_PKS_ER.1"
                     /evalue="1.50E-39"
                     /label="CFI07_RS22040_PKS_ER.1"
                     /locus_tag="CFI07_RS22040"
                     /protein_end="324"
                     /protein_start="15"
                     /score="127.9"
                     /tool="antismash"
                     /translation="SVQDVPSTKPGYGEVKVKLKSAGLNHRDLFLMKNKSEQDPHMILG
                     SDGAGIIEEIGEGVKNVTVQTEVVIFPTLNWDLTENVPPVPEILGGPSDGTLAEYVIIP
                     SQNAIKKPAYLSWEEAGVLPLSALTAYRALFTKGQLKKGEHLLIPGIGSGVATYALFMA
                     KAIGATVSVTSRSEEKRKKALKLGADYAFDSYSNWDEQLQGKKADVVLDSIGPALFSEY
                     FRHVKPNGRIVSFGASSGDNLSFPVRSLFFPQVNVLGTSMGSGEEFQAMLAFIDKHKLR
                     PVIDRIYPLEKACEAYKRMQEGRQFGNI"
     gene            10561..11418
                     /gene="yofA"
                     /locus_tag="CFI07_RS22045"
     CDS             10561..11418
                     /codon_start=1
                     /gene="yofA"
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389724.1"
                     /locus_tag="CFI07_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator YofA"
                     /protein_id="WP_003231468.1"
                     /transl_table=11
                     /translation="MESGDLKIFQAVAREGSITKAAQMLNYVQSNVTARVHNLEEDLNI
                     RLFHRTNRGMKLTAAGENLLQYADQVLSLLDQAEKSTRMSRQPKGPLRIGSLETMAVTH
                     LPEHAASFLRRFPEVDLSVNTADTHHLIQQVLDHKVDGAFVYGPVEHAAVRQLHVSHDE
                     LVLISSREGTAEDMLQQPMLFFGAGCSHRDRVKRLLEEAGIHNQKIIEFGTLEAIIKGV
                     SAGMGTALLPKSAVDGSEHRTNVWIHQLPPSYQDLEIVFIYRKDFFITSAFQTFLDEIN
                     EMKR"
     gene            complement(11519..13282)
                     /gene="ggt"
                     /locus_tag="CFI07_RS22050"
     CDS             complement(11519..13282)
                     /EC_number="2.3.2.2"
                     /GO_function="GO:0036374 - glutathione hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006750 - glutathione biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0006751 - glutathione catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ggt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1274: gamma-glutamyltranspeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389723.1"
                     /locus_tag="CFI07_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gamma-glutamyltransferase"
                     /protein_id="WP_014476980.1"
                     /transl_table=11
                     /translation="MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGK
                     DGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKT
                     KDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGT
                     RSMKQLITPSIKLAEKGFPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQ
                     KDLAKTFKLIRSKGTDAFYKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQ
                     GYQIATTPPPSSGGIFLLQMLKILDDFNLSQYDVRSWEKYQLLAETMHLSYADRASYAG
                     DPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKV
                     EGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQP
                     NKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIY
                     TNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISIDHENGTFKGVADSSRN
                     GAAIGINLKRK"
     misc_feature    complement(13322..13338)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.85"
                     /tool="antismash"
     gene            13467..13697
                     /gene="yoeD"
                     /locus_tag="CFI07_RS22055"
     CDS             13467..13697
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene="yoeD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389722.1"
                     /locus_tag="CFI07_RS22055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="excisionase family DNA-binding protein"
                     /protein_id="WP_003231472.1"
                     /transl_table=11
                     /translation="MYLTIEETAEYTNLSEDYIKSLVLEGKIRAVHDGEQFLIYKEQFK
                     THLEQLENYKALVQEILNEPIPEDIDVKDED"
     gene            14013..14558
                     /gene="yoeC"
                     /locus_tag="CFI07_RS22060"
     CDS             14013..14558
                     /codon_start=1
                     /gene="yoeC"
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389721.2"
                     /locus_tag="CFI07_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_003231473.1"
                     /transl_table=11
                     /translation="MHIVQPIRSLEKIQEVKQYLLNKNKRDYFLFIFGINSALRISDIL
                     PLQVKDVQNKDHLWATESKTKKKRKILILESLKQEIYEYTKDMKENEYLFKSVRTRKPI
                     SRIQAYRILREAAAACGLEEIGTHTLRKTFGYHFYQRTKDIAELQRILNHSSPSITMRY
                     IGIDEDTTRAAYKVFGGL"
     tRNA            14611..14683
                     /anticodon=(pos:791451..791453,aa:Arg,seq:cct)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="CFI07_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Arg"
     gene            14611..14683
                     /locus_tag="CFI07_RS22065"
     gene            complement(14777..15322)
                     /gene="iseA"
                     /locus_tag="CFI07_RS22070"
     CDS             complement(14777..15322)
                     /codon_start=1
                     /gene="iseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389720.2"
                     /locus_tag="CFI07_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DL-endopeptidase inhibitor IseA"
                     /protein_id="WP_004399558.1"
                     /transl_table=11
                     /translation="MKKCLLFLTTIALILSLSTNAFAKNTSGDLSQKQALQLALSAREH
                     FWNTMSGHNPKVKKAVCPSGTFEYQNLQYVYMCSDLGTKAKAVNYLTPIFTKTAIEKGF
                     KDYHFTVSKGKLAVPIGDGDNLLNWKKSTAKLISKKGSTITYEFTVPTLDGSPSAKRKV
                     TFVKENKKWKVNQFDAVI"
     misc_feature    complement(15550..15563)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.34"
                     /tool="antismash"
     gene            15608..16999
                     /gene="yoeA"
                     /locus_tag="CFI07_RS22075"
     CDS             15608..16999
                     /codon_start=1
                     /gene="yoeA"
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389719.2"
                     /locus_tag="CFI07_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MATE family efflux transporter"
                     /protein_id="WP_004399508.1"
                     /transl_table=11
                     /translation="METSQEPLVTQKKSKPSVWRSMSLFLVPLLLSNVLQSVGQLVGMM
                     AVGRWLGVDAVAAVSSFFPLFFLLISFTIGIGSGSSILIGQAYGAKNEERLKAVVGTTL
                     TFTFLLGVVLAVIGSIFTLDILRLMGTPENVIHVSANYARILFYAMPFMFLYFAYTTFL
                     RGTGDSKTPFYTLIVSTVINIALLPVLILGMFGFPKLGIYGSAYATVISTIATFLVLMV
                     YLRKRKHPLQFDKTVRRYLKMDKELLVLLLRLGVPASINMILVSLSEIAVISFVNHYGS
                     NATAAYGVVNQVASYVQMPAVSLGIAVSIFAAQSIGANEFDRLKQVIRVGIWLNYIIGG
                     VLIILIYVFSHQILSLFLTEQETLYIAHRLLMITLWSYLLFGNAQIISATMRASGTVLW
                     PTVISIFAIWGVEVPVAFVLSHYTKLEILGVWVGYPAAFAVSLLLIYGYYQFVWKKKQI
                     TRLIQ"
     misc_feature    17033..17042
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            17133..18110
                     /gene="galM"
                     /locus_tag="CFI07_RS22080"
     CDS             17133..18110
                     /EC_number="5.1.3.3"
                     /codon_start=1
                     /gene="galM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389718.1"
                     /locus_tag="CFI07_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldose 1-epimerase"
                     /protein_id="WP_046160453.1"
                     /transl_table=11
                     /translation="MANFIEKITYLGTPAIKAGNEHLEMIVVPEWGSNVISLVDKTTNV
                     QLLREPETAESFHDTPTLYGIPILFPPNRISDGTFSFRGRTYHFDINEKDKHNHLHGFL
                     YHEKWNVVTTKQTDEGVIVETEIDLSELPHVQNQFPHHAVVRMTYTIKGNTLFKHATVM
                     NKGKEAFPWGIGYHTTFVFPAESSLFSLTADQQWELDERLLPTGKLMDVPNKEALHEGM
                     DLRHKQLDDVFLSSYQKRGGENQAVIYHQHAHISIIYKADEHFNHWVVYNADGKQGYLC
                     PEPYTWVTNAVNLDLPSSLTGLQVLEPGEETTAKSSITIELNHQ"
     gene            18144..19619
                     /gene="dacB"
                     /locus_tag="CFI07_RS22085"
     CDS             18144..19619
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0004175 - endopeptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0009002 - serine-type D-Ala-D-Ala
                     carboxypeptidase activity [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="dacB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389717.1"
                     /locus_tag="CFI07_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="D-alanyl-D-alanine
                     carboxypeptidase/D-alanyl-D-alanine-endopeptidase"
                     /protein_id="WP_029318096.1"
                     /transl_table=11
                     /translation="MKKSIKLYVAVLLLFVVASVPYMHQAALAAEKQDALSGQIDKILA
                     DHPALEGAMAGITVRSAETGAVLYEHSGDTRMRPASSLKLLTAAAALSVLGENYSFTTE
                     VRTDGTLKGKKLNGNLYLKGKGDPTLLPSDFDKMAEKLKHSGVKVIKGNLIGDDTWHDD
                     MRLSPDMPWSDEYTYYGAPISALTASPNEDYDAGTVIVEVTPNQKEGEEPAVSVSPKTD
                     YITIKNDAKTTAAGSEKDLTIEREHGTNTITIEGSVPVDANKTKEWISVWEPAGYALDL
                     FKQSLKKQGITVKGDIKTGEAPSSSDVLLSHRSMPLSKLFVPFMKLSNNGHAEVLVKEM
                     GKVKKGEGSWEKGLEVLNSTLPEFGVDSKSLVLRDGSGISHIDAVSSDQLSQLLYDIQD
                     QSWFSAYLNSLPVAGNPDRMVGGTLRNRMKDTPAQGKVRAKTGSLSTVSSLSGYAETKS
                     GKKLVFSILLNGLIDEEDGKDIEDQIAVILANQ"
     misc_feature    19791..19804
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.64"
                     /tool="antismash"
     gene            20001..>23317
                     /gene="ppsA"
                     /locus_tag="CFI07_RS22090"
                     /pseudo=""
     CDS             20001..>23317
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Condensation_Starter (3-300). E-value:
                     8.9e-92. Score: 299.5. Matches aSDomain:
                     nrpspksdomains_CFI07_RS22090_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (463-864). E-value:
                     7.1e-113. Score: 369.2. Matches aSDomain:
                     nrpspksdomains_CFI07_RS22090_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (966-1035). E-value: 7.3e-26. Score:
                     82.2. Matches aSDomain: nrpspksdomains_CFI07_RS22090_PCP.1"
                     /codon_start=1
                     /gene="ppsA"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_389716.2"
                     /locus_tag="CFI07_RS22090"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="plipastatin non-ribosomal peptide synthetase
                     PpsA"
                     /pseudo=""
                     /sec_met_domain="Condensation (E-value: 9.7e-76, bitscore:
                     250.4, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-120, bitscore:
                     398.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 9.8e-15, bitscore:
                     50.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEHTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTL
                     EGALNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQA
                     SIPFKLFNSPLYQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDP
                     LPDQPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSAS
                     RDTIILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKA
                     EKEMLGMFVSSLPIRITVDPDTDFLSFVRTIGREQLSVMRHQRFPYNLLVNELRNEQKD
                     LHNLIGISMQYQPLQWHNADDFDYETALYFSGYTANELSVQIQERIDNGTIQLNFDYQN
                     TLFSLEDIKRIQSHLLTILENALQHPHSFIRELDMTNTREKQKLLYEFNRTVSVSPKAF
                     TLHGLFEQQAASTPERPAIRFSGGSLTYAELDMYASRLAAHLAARGVTNESIVGVLSER
                     SPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSAPNFSGETLE
                     VDMTSLECEEVKRHVSASVSDGSLAYVIYTSGSTGQPKGVAVEHRQAVSFLTGMQYQFP
                     LSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWEKDSALIVQAIHQENVTTAH
                     FIPAMLNSFLYQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVSLIHGYGPTE
                     ATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGELYIAGAGVAR
                     GYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVKIRGYRIEPG
                     EIEAALRSIEGVREAAVTVRTDSGEPELCAYVEGLQRNEVRAQLERLLPGYMVPAYMIE
                     MEQWPVTPSGKLDRNALPAPGGAADAETYTAPRNVTEMKLSQLWEDVLKNGPVGIHDNF
                     FDRGGHSLKATALVSRITKEFDVQVPLKDVFAHPTVEGLATVIREGTDSPYEAIKPAEK
                     QETYPVSSAQKRIYVLQQLEDGGTGYNMPAVLELEGKLNPERMDRAFQELIKRHESL"
     aSDomain        20010..20900
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CFI07_RS22090_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="8.90E-92"
                     /label="CFI07_RS22090_Condensation_Starter.1"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="300"
                     /protein_start="3"
                     /score="299.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHIIMDG"
                     /tool="antismash"
                     /translation="HTYSLTHAQRRVWFTELLEPDTSICNLTACVKFKGNIELDTLEGA
                     LNHSISRNDAIRFQLLEGEELEPRLHLTEYKYYPLRIIDFSNVEMIEIEQWIQDQASIP
                     FKLFNSPLYQFYLLRIDSHEVWLFAKFHHIIMDGISLNVMGNQIIDLYQKMKKKDPLPD
                     QPEPSYLSYIEKESQYLQSPRFAKDRLFWTQTFEHPLEYHSLADQTSLQKQSTSASRDT
                     IILSPDLEQTIRIFCEEHKINIISLFMASFYICISRITSKKDLAIGTYYGNRGSKAEKE
                     MLGMFVSSLPIRITVD"
     aSModule        20010..23105
                     /complete
                     /domains="nrpspksdomains_CFI07_RS22090_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_CFI07_RS22090_AMP-binding.1"
                     /domains="nrpspksdomains_CFI07_RS22090_PCP.1"
                     /locus_tags="CFI07_RS22090"
                     /monomer_pairings="Glu -> Glu"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20016..20054
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0001"
                     /evalue="6.90E-03"
                     /label="C1_starter_004-017"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="18"
                     /protein_start="5"
                     /score="9.4"
                     /tool="antismash"
                     /translation="YSLTHAQRRVWFT"
     CDS_motif       20079..20195
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0002"
                     /evalue="3.00E-08"
                     /label="C2_starter_024-063"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="65"
                     /protein_start="26"
                     /score="26.3"
                     /tool="antismash"
                     /translation="ICNLTACVKFKGNIELDTLEGALNHSISRNDAIRFQLLE"
     CDS_motif       20400..20465
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0003"
                     /evalue="1.20E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="155"
                     /protein_start="133"
                     /score="24.6"
                     /tool="antismash"
                     /translation="FHHIIMDGISLNVMGNQIIDLY"
     CDS_motif       20799..20888
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0004"
                     /evalue="1.50E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="296"
                     /protein_start="266"
                     /score="27.1"
                     /tool="antismash"
                     /translation="DLAIGTYYGNRGSKAEKEMLGMFVSSLPIR"
     CDS_motif       20940..21053
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0005"
                     /evalue="5.60E-09"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="351"
                     /protein_start="313"
                     /score="28.6"
                     /tool="antismash"
                     /translation="REQLSVMRHQRFPYNLLVNELRNEQKDLHNLIGISMQY"
     aSDomain        21390..22592
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CFI07_RS22090_AMP-binding.1"
                     /evalue="7.10E-113"
                     /label="CFI07_RS22090_AMP-binding.1"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="864"
                     /protein_start="463"
                     /score="369.2"
                     /specificity="substrate consensus: Glu"
                     /tool="antismash"
                     /translation="FEQQAASTPERPAIRFSGGSLTYAELDMYASRLAAHLAARGVTNE
                     SIVGVLSERSPDMLIAVLAVLKAGGAYLPLDPAYPKERLSYMLKDSGASLLLTQPGCSA
                     PNFSGETLEVDMTSLECEEVKRHVSASVSDGSLAYVIYTSGSTGQPKGVAVEHRQAVSF
                     LTGMQYQFPLSEDDIVMVKTSFSFDASVWQLFWWALSGASAYLLPPGWEKDSALIVQAI
                     HQENVTTAHFIPAMLNSFLYQAEIERLSDRTSLKRVFAGGEPLAPRTAARFASVLPQVS
                     LIHGYGPTEATVDAAFYVLDPERDRDRLRIPIGKPVPGARLYVLDPHLAVQPSGVAGEL
                     YIAGAGVARGYLNRPALTEERFLEDPFYPGERMYKTGDVARWLPDGNVEFLGRTDDQVK
                     IR"
     CDS_motif       21576..21617
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0006"
                     /evalue="6.90E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="539"
                     /protein_start="525"
                     /score="19.1"
                     /tool="antismash"
                     /translation="LAVLKAGGAYLPLD"
     CDS_motif       21801..21860
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0007"
                     /evalue="4.70E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="620"
                     /protein_start="600"
                     /score="34.4"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGQPKGVAVEH"
     CDS_motif       22386..22475
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0008"
                     /evalue="6.70E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="825"
                     /protein_start="795"
                     /score="56.7"
                     /tool="antismash"
                     /translation="PSGVAGELYIAGAGVARGYLNRPALTEERF"
     CDS_motif       22557..22622
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0009"
                     /evalue="6.10E-13"
                     /label="NRPS-A_a8"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="874"
                     /protein_start="852"
                     /score="40.5"
                     /tool="antismash"
                     /translation="FLGRTDDQVKIRGYRIEPGEIE"
     aSDomain        22899..23105
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CFI07_RS22090_PCP.1"
                     /evalue="7.30E-26"
                     /label="CFI07_RS22090_PCP.1"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="1035"
                     /protein_start="966"
                     /score="82.2"
                     /tool="antismash"
                     /translation="EMKLSQLWEDVLKNGPVGIHDNFFDRGGHSLKATALVSRITKEFD
                     VQVPLKDVFAHPTVEGLATVIREG"
     CDS_motif       23154..23189
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0010"
                     /evalue="3.40E+00"
                     /label="C1_starter_004-017"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="1063"
                     /protein_start="1051"
                     /score="1.6"
                     /tool="antismash"
                     /translation="YPVSSAQKRIYV"
     CDS_motif       23220..23315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CFI07_RS22090_0011"
                     /evalue="7.30E-14"
                     /label="C2_LCL_024-062"
                     /locus_tag="CFI07_RS22090"
                     /protein_end="1105"
                     /protein_start="1073"
                     /score="44.1"
                     /tool="antismash"
                     /translation="YNMPAVLELEGKLNPERMDRAFQELIKRHESL"
ORIGIN
        1 taaaaaacag ctgaaggtag agctggatcg ctgtaaaaaa ctgattgaaa aagctctctc
       61 agataatttt taatagaaac aaacacccgg cgcagcagtg tgaaccgggt gttttctgct
      121 tttcattata catatttgtc gaaaagaaac aatacaaatc aatgatgacc ttcaaacttg
      181 acatcatttc ctcacgtggt aacattttaa acgtgtgaaa atgcgaacaa aaaagcgaac
      241 aaaggagatg ttaccgatct ttgatcaaaa gaaagtagcc tttataggag caggatctat
      301 ggcggaagga atgatatcag gtatcgttcg tgccaacaaa atcccgaaac aaaacatctg
      361 cgttacaaac cgcagcaata cagagcgatt aactgaactt gaacttcaat atggaatcaa
      421 aggcgccttg ccgaaccaac tatgtattga agacatggat gtactcattt tggcaatgaa
      481 gccaaaagac gccgaaaacg ctctgtcatc actaaaatca cgtattcaac cccatcaatt
      541 aatattgtcg gtccttgccg gcataaccac ctcttttatt gaacaatcat tgcttaatga
      601 acagccggtt gtcagagtga tgcccaacac ttccagtatg attggcgctt ctgcaacagc
      661 tattgccctt ggcaaatatg tgtcggaaga cctgaagaag ctggccgaag cattgctcgg
      721 atgcatgggc gaagtctata caatccaaga aaatcaaatg gatatattca ccggaattgc
      781 aggcagcggc cccgcgtatt tttattattt aatggaattc attgaaaaga caggcgagga
      841 agcgggcctc gataaacagt tatctcgaag catcggcgca cagacacttt taggtgccgc
      901 aaaaatgctc atggaaacag gagaacatcc tgagatctta agagataata tcacgtcacc
      961 taacggaacg acagcagcgg ggctgcaagc cttgaaaaaa agcggcggcg gagaagcgat
     1021 ttctcaagcg ataaagcatg cggctaagcg ttcaaaggaa atcagcgaag atatcgaaaa
     1081 aactgcagcg ccgctatcag gagtgataaa gtgacgcctg atacaagcat gaaaagagtc
     1141 gttgtgaaga ttggaagcag ttcattaaca agccttcatg gagaaatcag cattcgtaaa
     1201 ttagaagcgc tggtcgacca ggtcgtcaaa ctcaaagacg ccggttatga agtgattttg
     1261 gtttcctcag gcgcagtggc ggcgggatat cggaagctcg gatttatcca aaggcccgag
     1321 aagcttccag aaaaacaagc atcagcttca atcggccagg gattgctgat ggaggcttat
     1381 tcaaagctgt ttttggcaca cggctatgtc gcatcccaaa ttttaattac gagaagcgat
     1441 ttttctgatg aatatcgata caacaatgtc aggaatacaa tgaatgtact gctcgagcgc
     1501 ggcatcatcc cgatcataaa cgaaaatgac acagttaccg tcaatcggct caagtttggc
     1561 gacaatgata cgctcgcagc aaaagtcgca ggattgattg atgcagatat gcttgtgatt
     1621 ttatcagata tcgacggatt atatgacggc aatccgcgca caaatccaga agcgaaaaga
     1681 atacagcggg tgagtgaaat aacacctgac atcgaagcat gcgcaggtga cactggaagc
     1741 atcgttggca ccggcggcat gcgctctaag cttgatgcgt ttaaaatcgt aatggcgtct
     1801 ggcattaaag gtttcctagg tcaggcagat gtcggcgata ttttatatca cgccgttcat
     1861 gaacaggcgg aaggcaccta ttttgaagca gaaggaacgc ttccgttgaa tcaaaaggag
     1921 caatggatcg cttttaattc cggtccggaa ggtgaaatga ttttatcaga tgattgttca
     1981 cgaaaaataa caaacggcca atcgagttta tacctagacg gtgtacagaa gattaaaggg
     2041 aaatttaaaa gcggttcagt tgttcggcta atggattcaa aagggacgga aatcggcctt
     2101 ggaatcgtca attactcttc tgtacagctt caagaaccgg aaaagaacaa ggaactgaca
     2161 aacagagctc taattgatca agaagcattt gtttgccatg tggatttttc tttacctgta
     2221 aattaatttg cagaaaaaaa cccgaagctt ctatatagaa gctcgggttc atttttttta
     2281 ttgatactgc tccagcttag agaaaaattg aatgacaaac tcataaaaat cattcgcgga
     2341 aggcgcaagc tctctatttt tcggtttaat gattccgaca gtccgtttta cttgagggaa
     2401 ctcaattgga attttcacag taaaacgagg tgttgtttca gcaaaagtac tttcaggcag
     2461 aagggtaacg cccattcctg cggacactaa ccctttgata gcatccaaat cctcaccctc
     2521 cgtggaaacg agaggagcaa agcctgcttg tttgcaagta tcgattgcca tctctctaag
     2581 tacaaatcct tccgggaaca atacaaattg gtcgttgcgc aaatcgatta aatgaaccgt
     2641 tttttgttta gcaagcggat gatttaatgg aacaagcgcg taaatttttt cagtaaataa
     2701 tatttttccc gttatgtcag agaaattcgt cggcaccggt cctaataagg ccagatcaat
     2761 atcgcggttt ctgacagctt caatcagaaa cttataggag ccttggcgca gcaaaaattc
     2821 gacgtgcgga tattcttctt taaacgctga aatgacagtc ggcaaaagct ggctggcgag
     2881 gcttgtagga aagccgatct ttaccgttcc gcgatgcggg tcaagatact catcaatttg
     2941 ctctttcgca taatcaatgg ctttcatcgc cgttttcaca tgaatcaaaa attcttttcc
     3001 gattggcgtg agtttgatat ttctcccttc acgctcaaat aaggtcacat ttaattcttc
     3061 ttcaagattg gcaatttgtc tgctgattgc tgattgggcc acatgcaaat gatcagcggc
     3121 ttctgaaacg tgttctcttt cagccacctc catgaaataa cgcagttggc gcagctccat
     3181 gtttgtctca catccatcta tctcattttg agattctttt gatctaaatt atatattgtt
     3241 tatatcgttt tgaaaaccta caatgattat agagttgtta gattttatga ccggtattat
     3301 cggaaattga tcgggggaga gaaattatga cgtacaatca aatgccaaaa gctcaaggtc
     3361 tctaccgtcc tgaatttgaa catgatgcat gcggaatcgg cctatatgca cacttaaagg
     3421 gcaagcagac tcacgccatt gtcaaacaag gacttaagat gctttgccag ctagaccata
     3481 gaggagggca aggcagtgat ccggatacag gagacggagc cggcttactg gttcaaatcc
     3541 ctgatgcttt ctttagaaaa gagtgcaaag acatcaatct gccagaaaaa gaacgttacg
     3601 gggtaggaat ggtctttttc tcacagaaag aagatgaaag aaaaaaaatt gaaaagcaaa
     3661 tcaatgcact gattgaacaa gaaggccaag tcgttcttgg atggagaact gtacctgtaa
     3721 atgtcggaaa aatcggaaca gtggcgcaaa aaagctgtcc gtttgtccgt caggtattta
     3781 tcggcgcaaa ttctgatcta aaggacaatt tatcttttga acgaaaattg tatgtcattc
     3841 gtaaacaggc tgaaaattgg ggagtaacgg aaggtcttga tttttatttt gccagtcttt
     3901 caagccagac cattgtttac aaaggccttt taacacctga acaggttgat gcattttatt
     3961 ctgatctgca agacgaagca ttcgtttctg cttttgcgct tgttcattca cgcttcagta
     4021 ccaatacatt ccctacatgg gaaagagcgc atcctaaccg ctatttggtt cacaacggtg
     4081 aaattaacac ccttcgcgga aatatcaact ggatgagagc acgtgagcag caatttgttt
     4141 ctgaaagctt cggtgaggac ttaaacaaga ttttgccgat tctcaatgct gatggcagtg
     4201 actcttccat tttggataac gcatttgagt tttttgtgat ggctggacgc aaaccggcac
     4261 atacggcaat gatgctcatt ccagagcctt ggacggaaaa tacgcatatg tccaaggaaa
     4321 aaagggcgtt ctacgagtac catagctccc tgatggagcc ttgggacgga ccaacagcca
     4381 tttcatttac tgacggtaaa caaatcgggg cgatccttga tcggaatggt ctccgtccgg
     4441 cccgttatta tgtcacaaaa gatgattata ttattttctc atctgaagta ggcgttattg
     4501 aagttgaaca ggagaacgtt ttatataaaa accgccttga gcctgggaaa atgcttttaa
     4561 tcgacctgga agaaggccgt attatctccg atgaagaagt caaaacacaa attgcaactg
     4621 agtatccgta tcaaaaatgg cttgaagaag agcttgtaca agtaaatcct gatccggagt
     4681 caagagaaga agaacaattt agtgatcttc ttactcgcca gaaggcattc ggatacacat
     4741 atgaagatat ccaaaaatat ctaattcctg ttattaaaga aggcaaagat ccccttggtt
     4801 caatggggaa tgatgctccg cttgctgtac tttctgaccg agcgcaatca ctgtttaact
     4861 actttaaaca gctgtttgca caagtaacga acccgccaat cgacgcgatt cgtgagcagc
     4921 ttgtcacttc aacgatgact tggctcggtg cggaaggcga tcttcttcat ccgagtgaac
     4981 gaaatgttcg ccggattaaa ctgtatacac ctgttttatc caatgaacag ttttacgcat
     5041 tgaaaacgat tgttcatcct gatttaaaaa gccaaaaaat tgatgtgctg ttttcagagg
     5101 atcttgaacg cggattaaag gacatgttca cacaagcaga gaaagccatc agccaaggcg
     5161 taagtttgtt aattttatca gacaaaaaga tgaacgaacg actgacacca attccgccgc
     5221 ttctggcagt aagcgcactg caccagcact taatccgcaa agggctgcgt acgaaggtca
     5281 gcattattgt ggaatcggga gaagcacgtg aagtgcatca ctttgcagcg ttaatcggtt
     5341 atggcgcaga tgcgattaac ccttatctcg cttatgcgac ctacaagcag gaaattgatg
     5401 aaggccgttt ggatatcagc tatgaagaag cggttagcaa atatggaaaa agcattactg
     5461 agggcgtcgt aaaagtgatg tccaagatgg gaatttcaac tgtgcaaagc tacagaggcg
     5521 cacaaatctt tgaggcggta ggaatcagcc gcgatgtgat cgaccgctat ttcacaggta
     5581 ctgcatcaca gctaggcggc atcgatttac aaacaattgc agaagaggca cagcgccgcc
     5641 accgggaagc gtatcaggat gattacagca aaacgcttga accgggaagt gacttccaat
     5701 ggagaaatgg cggagagcat catgcgttta atccgaaaac gattcatact ttgcaatggg
     5761 cgtgccgcag aaatgattac aatctgttta aacagtatac aaaagcggct gatgaagaac
     5821 gcatcggatt tttgcggaac ttgttcgcat ttgacggaaa ccgcaagcct ttgaagttgg
     5881 aggaggttga atccgctcaa tcgattgtca aacgttttaa aacgggtgcg atgtcattcg
     5941 ggtccttgag taaggaagcg cacgaagctt tagcaatcgc aatgaaccgt cttggaggaa
     6001 aaagcaacag cggtgaaggc ggagaagatc ccaaacgctt tgttccagat gagaacggcg
     6061 atgatagaag aagtgcgatc aaacaaattg catccggacg gtttggtgtc aaaagccatt
     6121 acctcgtcaa tgctgatgag ctgcagatta aaatggctca aggtgctaag ccgggtgaag
     6181 gcgggcagct tcctggcaac aaggtatatc catgggttgc cgatgtccgc gggtcgacgc
     6241 caggtgtcgg attaatctca cctccgccac accatgacat ttattcgatt gaggatttag
     6301 cccagctgat ccacgatttg aaaaatgcca accgtgacgc aagaatcagc gtaaagctgg
     6361 tgtcaaaagc aggtgtagga acaatcgctg caggtgttgc caaagcgact gcagatgtca
     6421 ttgtgatcag cggctatgac ggaggtacag gcgcttctcc gaaaaccagt attaaacata
     6481 cagggcttcc gtgggagctt ggccttgcag aagcacatca aacactaatg ctgaacggac
     6541 ttcgtgaccg tgttgtatta gaaacagacg gaaagctcat gacgggccgc gacgttgtga
     6601 tggctgcctt gctcggcgcc gaagaatttg gtttcgcaac ggctccgtta gttgtactcg
     6661 gctgtgtcat gatgcgtgcc tgccatttgg atacatgccc tgtcggtgta gcgacacaaa
     6721 acccagagct tcgcaaaaag ttcatggggg atcctgacca tattgtgaac tatatgctgt
     6781 tcattgctga agaagttcga gagtacatgg ctgcgttagg cttcaagaca tttgatgaaa
     6841 tgatcggccg cactgatgta cttcatgtaa gtgaacgggc gaaggggcac tggaaagcaa
     6901 gccagcttga tttgtctaca cttctttatc agcctgaagg ggtgcggacg ttccgatcgc
     6961 cgcaaaatca taaaattgat caatcgcttg atatcacaac aattctcccg gctgtacaag
     7021 aagccatcga atctggaaaa gaagctgata tttcgattga aatcaataat acaaatcgtg
     7081 tagccggaac gataaccggc agtgaaatct caaagcgtta cggagaagaa ggtcttcctg
     7141 aagatacaat caagctgcac tttaccggat cagccggcca aagctttgga gctttcgttc
     7201 ctaaagggat gacgctttat ttggacggag actcaaatga ttacgtcgga aaagggcttt
     7261 ctggcggaaa aatcatcgtc aagtcaccag aaggattcaa ctctgcttcg gatgacaatg
     7321 tcattatcgg caacgtggct ttttacggtg cgacaagcgg agaagcatat attaacggac
     7381 gtgctggtga acgctttgcc gttcgaaaca gcggtgtgaa cgtagttgta gaaggtattg
     7441 gcgaccacgg ctgtgaatac atgactggcg gcagcgttgt cgttctcggt gatgtaggca
     7501 aaaactttgc ggcaggtatg tccggcggaa tcgcttatgt actggccgaa gatgtcaaag
     7561 cgtttaaacg caaatgcaac cttgagatga ttttatttga atcattagag gacgagaaag
     7621 aaatccagca aatcaaagca atgcttgaaa gacatactgc atatacaaac agccaaaaag
     7681 cagaagattt gcttgatcaa tgggaagaca gtgtgaaaaa attcgtcaaa gtcattccga
     7741 aaaactataa acaaatgctc gcaagcatcg aagagcaaaa agctgcaggt ttatcagatg
     7801 aagaagccat catgttcgct tttgaggcca acacgaagcc aaagcagaat acagcagcat
     7861 cgggacaaaa acaagcggta gtacagtaag gaaggggaga ggaacatggg gaaaccaact
     7921 ggatttatgg agatcaaacg agaaaaacct gcggagcggg accctctcac tcgcttaaag
     7981 gattggaaag aatattctgc tcctttttca gaagaagcat cgaaacggca gggggcgcgg
     8041 tgcatggatt gcggtacacc gttttgccag atcggtgcgg acattaacgg atttacatcc
     8101 ggctgtccga tttacaactt aattcctgaa tggaatgatc ttgtctaccg gggcagatgg
     8161 aaggaagcat tggaacgcct gttgaaaaca aacaactttc ctgaattcac agggcgggta
     8221 tgtcccgctc cttgtgaagg atcatgcact ttagcgattt cagacccggc cgtttcaatt
     8281 aaaaatatcg agcgaaccat tatcgacaaa ggatttgaga acggctggat tcaacctaga
     8341 attcctaaaa aacgaacagg caaaaaagtg gccatcgtcg ggtcaggccc agccggactg
     8401 gcgagtgctg accagctgaa tcaagcggga cattccgtca ctgtttttga acgagcagac
     8461 agagcgggcg gccttttaac atacggcatt ccaaacatga agcttgagaa gggcattgta
     8521 gaacgccgaa ttaaattgct gacgcaagag ggaattgatt ttgtcacgaa cacagaaatc
     8581 ggtgttgaca ttacagctga tgagctaaag gagcaatttg atgctgtggt cttatgcaca
     8641 ggcgctcaaa aacagcggga cctcttaatt gaaggacgcg actcaaaagg agtccattac
     8701 gcaatggact acctcacact tgcaacaaaa agctatttag attctaattt taaagacaag
     8761 caattcattg atgccaaagg gaaagatgtc atcgtaatcg gaggcggaga tacaggagct
     8821 gactgtgtgg ctaccgctct gcgtcaaaaa gccaaaagcg tgcaccaatt cggcaaacac
     8881 ccgaaacttc cgccagcccg cacgaatgac aatatgtggc ctgaacagcc acacgtcttt
     8941 acgcttgaat atgcatacga ggaagcagaa gcaaaattcg gaagagatcc gagagaatac
     9001 tccattcaaa cgacaaaaat ggtcgcggat aaaaacggaa agctgaaaga gcttcatacc
     9061 atccaaatgg aaaaagtgaa aaatgagcat ggaaaatacg agttccgcga gctgcctgga
     9121 acggaaaaag tatggcctgc tcagcttgtc tttatcgcta tcggctttga aggcacagaa
     9181 cagccgctgt tgaaacagtt cggtgttgat tcagtaaata acaaaatcag tgcagcatat
     9241 ggggattatc aaacaaatat cgatggtgta ttcgccgcag gggatgcaag aagagggcaa
     9301 agcttaatcg tatgggcgat taatgaaggc cgtgaagtgg cgcgtgaagt ggatcgatat
     9361 ttgatgggga gttcagttct tccgtaaata aaggggatta tcatataaga gaaaccggtc
     9421 tggctgccag ccggtttctt tttttattcc attacgatcc cgatgtttcc aaactgtctg
     9481 ccttcctgca ttcttttata tgcttcacat gctttttcta aaggatatat ccggtcaatt
     9541 acaggccgca gcttatgttt gtcaatgaaa gcgagcatag cttgaaattc ctcaccgctt
     9601 cccatcgagg ttcccaaaac attgacctga ggaaagaata gagaacgcac cggaaaactg
     9661 agattatccc ctgagcttgc cccaaagctg acaatacggc catttggttt tacatggcgg
     9721 aagtattccg aaaagagggc aggtcctatg ctgtcaagaa caacatccgc cttttttccc
     9781 tgcaactgct catcccaatt gctgtagctg tcaaatgcgt aatcagcacc taatttcagc
     9841 gccttttttc ttttctcctc actgcgggag gtcacgctta ctgttgcccc aatcgcctta
     9901 gccataaata aagcgtaggt tgctacaccg ctgccgatgc cgggtatcaa tagatgctcg
     9961 ccttttttta attgcccctt tgtaaacaga gcccgatatg cagttaaagc ggataaaggt
    10021 aaaacgcccg cttcttccca agataaataa gcaggttttt tgattgcatt ttgtgaagga
    10081 atgatcacat attcagcaag tgttccgtcc gaaggacctc ccagaatctc aggtacaggt
    10141 ggaacatttt ctgtcaaatc ccagttcaat gtcgggaaaa tgactacttc tgtctgaaca
    10201 gtaacatttt tcacgccttc accaatctct tcgatgatac ccgcgccgtc agaacccagt
    10261 atcatgtgag gatcttgttc agatttgttt ttcataagaa acaagtcacg atgattcagg
    10321 cctgcagatt ttaatttaac ctttacctct ccgtatccag gctttgttga tggaacgtcc
    10381 tgaactgata accccagaag accggctttt ccgttgtgaa ttacagcttt catgctgtct
    10441 gcctcctcat taattgtatt ttcatatctt tacatatttt acatagcggt tttcttcgag
    10501 taaaatgaac aaatatgata gccaatatca cttttcatca tagcaagcag gtgagagcgc
    10561 gtggaaagcg gagatttaaa gatttttcag gctgttgctc gcgaaggaag cataacgaaa
    10621 gcagcccaaa tgctgaatta tgttcagtcg aatgtgacag ccagagtgca taaccttgag
    10681 gaagatttga atatcaggct ttttcatcga acgaatcggg gaatgaagct gactgctgca
    10741 ggagaaaatc ttttacaata tgcagatcaa gtattatcgc tgttagacca agctgaaaaa
    10801 tcgacccgaa tgagcaggca accaaaaggg cctttgcgga tcggatcact ggaaacaatg
    10861 gcggtaacgc atctgcctga gcatgcagca tccttcctca ggcgttttcc tgaagtggat
    10921 ttatcagtga acacagctga tacgcatcat ttgattcaac aggttcttga tcataaagtt
    10981 gatggcgctt ttgtatatgg gccggttgaa cacgctgcag ttagacaact ccatgtctcc
    11041 catgatgaat tagttttgat ttcatcacga gaagggacgg cagaagacat gcttcagcag
    11101 ccgatgctct tttttggggc tggctgttct catcgtgaca gggtcaaaag attactagag
    11161 gaagcaggca tacacaatca aaaaatcata gagtttggca cattggaggc tattataaaa
    11221 ggtgtttccg ccgggatggg tacggcgctg ctcccaaagt ccgctgttga cggctccgag
    11281 catcgtacaa atgtatggat tcatcagctg ccaccatcat atcaagactt agagatcgtc
    11341 tttatataca ggaaagactt ttttattacg agtgcgtttc agacatttct tgatgagata
    11401 aacgaaatga aaagatgaag atagacgtgc attagcagaa taaagacgtt tgtcagtttt
    11461 tattttaaag atctgcatga aaaaactgta ctcatttgaa gcgagtacag ttttttattt
    11521 atttacgttt taaattaatg ccgatcgccg cgccgtttct gcttgaatca gctacacctt
    11581 taaaggtgcc gttttcatgg tcgatcgata tactttgcac gtttccgata tccaccggac
    11641 ttgtgccgaa tttgtggccc atgccgttta gcttgctgag gacatcttta ggaactccgt
    11701 cttcgtaacg gtaagagctc atgctgtttg tgtaaattct cggctcttca acagctgctt
    11761 ttaattccat accatattca atgtggtaga gaatggtttg caaaactgat gaaataattg
    11821 tggccccgcc aggagatcca accgtgagga caggcttgtc atccttaaat aaaatcgtcg
    11881 gggtcatgct gcttaaaggc cgtttgtttg gctgtacttc gttagctccg cctggtatcg
    11941 catcaaaatc cgttaattca ttgtttagga tgacaccgta atcagggacc ataatacccg
    12001 ttccaaacaa ctgttcgatt gttgttgtat aagaaacaac atttccccat cgatcagcaa
    12061 ctgtaaagtg ggttgtttgg ccttctactt tgtctttcgg ctgttcaact tgtttatagt
    12121 ttgctgatcc ttcttggtat ttccaagggt caccggcttt cggtttttta ttcacttgat
    12181 ctaggttgat taattgctgg cgttctttaa tataatcggg gtgaagcagg cctttgagag
    12241 gaacatttac aaattcggga tcacctgcat aagacgcacg gtcggcatat gacaaatgca
    12301 tcgtttcagc aagcagctga tatttttccc atgagcggac atcgtattgt gaaaggttaa
    12361 aatcatcaag gatttttagc atttgcaata agaaaatacc gccggagctt ggaggaggag
    12421 tagtagcgat ttgatagcct tgatagtctc cccaaatcgg ttcatcaatt gtaatgtcgt
    12481 aattttctaa atctttttct gtcattgatc cgccgaaatc ctggacagtg tcagaaagcg
    12541 tcttggcgaa ttttccttta taaaaagcgt cagtgccttt ggagcgaata agcttaaatg
    12601 ttttagccaa atccttttga ataagggtat ctccttcttt aagcggttcg ccatttggta
    12661 aaaatacatc ttttgcggca gtccgtgaaa gcttttcctg ataatcagaa atggcctctg
    12721 ccaacaccga atcaatcgga aagccttttt cagcgagttt aatagaaggg gtaattaatt
    12781 gcttcatcga acgggttccc catttatcca aggcttcttc cagccctttc agagtgcctg
    12841 gaacaccaac ggcagtacct tttgttacac gttcagagaa aggaattgct ttgccgtttt
    12901 cgtccagaaa catatcagga gttgcgcctg ctggagcacg ctcacggctg tcgattatcg
    12961 ttgtatcctt cgtttttccg tcatacacca tcataaaacc gccgccgcca atacctgaca
    13021 tcatcggctc tgttacattg agtgcaaatt gaatggcaac cgctgcgtca atagcatttc
    13081 ctcctttttt cagcacatca gcaccgattt cagaagcaag aggatgtgcg gtcgcaacca
    13141 tgccgtcttt tccaacatct acttgtttgt actcatcgta gcttttgggc ggttttttag
    13201 cttccgcgtg aaaagggaca cttccagcga ctaacagaac actaagcaga gctgttaaac
    13261 agacgttcca cgttcttttc atgttctccc tcctatatga agctgtattg ttacaatctt
    13321 agcgtaaaaa aattacagcg ttttcacaag tgacaaatgg tatattatat agtgcataat
    13381 gccgtttttc tgtgcaaaat tgattatatt gatatgagcc atgtgctata ttagaatcag
    13441 catacggatt aagaagggac tgctatatgt atttaacgat tgaagaaaca gcagaatata
    13501 caaatctttc agaggattat attaaaagct tggtgctcga agggaaaatc agagccgttc
    13561 atgacggaga gcaatttttg atttataaag agcagttcaa aacgcatctc gaacagctgg
    13621 agaattacaa agcacttgtg caggaaatat taaatgaacc aatcccggaa gatattgatg
    13681 taaaggatga ggattaggac acaatttgaa attgtgtctt tttttgtata tttttgcgga
    13741 agctctagaa aattaggagt gtcagatttc gttttaagag gttttttgat gattagtagg
    13801 gggataagta tccaagaggt taaaagcttt ataagaggct ttaaagctta ttttataggg
    13861 tgaaggttgg aagaagcttt tttaaaagct tatgtaacac tatgtatatt atgttacata
    13921 aacgccgccg cactttgaca ttcaacgttt ttcagctata atagtaacat agacctcaaa
    13981 acgttacata acggttttta aggagttttt tgatgcatat tgtacagccg attcgcagtc
    14041 tagagaaaat ccaagaagtc aaacagtatt tgcttaacaa aaacaagcgg gattattttc
    14101 tgtttatttt cggcatcaac agcgcgctcc gcatttctga tattctgccg ctgcaagtga
    14161 aggacgttca aaataaagat catttatggg cgactgaaag caaaacgaaa aagaaaagaa
    14221 agattcttat tttagaatcg ctgaaacagg aaatatacga gtatacgaaa gacatgaagg
    14281 aaaacgaata tctttttaaa tcagtgcgga ccaggaagcc gatttcccgc attcaggcct
    14341 acagaatttt aagagaggcc gctgcggcgt gcggacttga ggagataggg acgcatacac
    14401 tccggaaaac gtttggctat catttttatc agcgaacgaa agacatcgcc gagctgcaga
    14461 gaatactgaa tcattcatca ccatcaatta caatgcggta tatcggtatt gatgaagata
    14521 caactagagc cgcatataag gtttttggag ggctttaata caaatcgctt gaaaatattg
    14581 atcatcagag ctactatata aataccaaaa gctctagtag cacagcggat agtgcagcag
    14641 tttcctaaac tgcaggtcgg gagttcgaat ctctcctaga gcgttatatt cacaaaaaga
    14701 caacaggcac ttttcgcctg ttgtctttct ttatgcagac caaataaaaa acgcccgctt
    14761 atcccgggcg tttttcttat ataactgcgt caaattgatt gactttccat tttttatttt
    14821 ctttcacaaa tgtcactttc cgttttgcag aaggggatcc gtctaatgta gggacggtaa
    14881 attcgtatgt gattgtgctg ccttttttag agatcagttt agcagttgat tttttccaat
    14941 tcaaaagatt gtctccgtca ccgattggaa cagcaagttt tccttttgaa acagtaaaat
    15001 gataatcttt aaagcctttt tcgattgctg tttttgtaaa aataggagtt aaataattca
    15061 ccgcttttgc tttagtgcct agatcactgc acatgtatac atattgaaga ttttgatact
    15121 cgaatgtgcc tgatgggcaa actgcttttt tcaccttcgg attgtggccg ctcatggtgt
    15181 tccaaaaatg ttctctagcg gataatgcca actgtaatgc ttgtttttgt gataaatcgc
    15241 ctgatgtatt tttcgcaaat gcatttgtgc ttaatgacag aataagtgca atggttgtta
    15301 gaaatagaag acattttttc attatcgctc tctccttcaa aatctctttc tcttatgtta
    15361 caaatgttac aataattacg gatagattac aatacttttg cataaattat tttttattct
    15421 tttactcaca aaaaatacgc cattacttgc tagtttattc ttcataagct aaaaagatgt
    15481 gtaaaattag aagaatcggg aagggtttca tatgtgcagt gatgaataat aacatgttgc
    15541 atatcctgtt tttgtcaaaa aatgagggca tgtttaaaaa cgatttcaaa taaaggagtc
    15601 ctttaatatg gaaacatcac aagaacctct tgtaactcaa aagaaaagca aaccatcagt
    15661 ttggcggtcg atgtcactct ttttagtgcc gcttctgctg agcaatgtgc tgcaatcagt
    15721 cggccagcta gtcgggatga tggctgtagg cagatggctc ggtgttgatg cagtggcagc
    15781 tgtatcatcc tttttcccgt tattttttct tttaatctca tttacgattg ggatcggttc
    15841 aggtagttcg attctgatcg gacaagctta cggagcgaaa aatgaggaac ggctaaaggc
    15901 tgttgtcggg acgacgctca cgtttacatt tttattaggc gttgtgttag ccgtcatcgg
    15961 cagtattttc accctggata tccttcgttt aatgggcacg cctgaaaatg tcattcatgt
    16021 cagcgctaac tatgcacgta ttttatttta tgctatgccg tttatgtttt tatattttgc
    16081 atatactacc tttttgcgcg gaacagggga ttctaagaca ccgttttata cgctgattgt
    16141 gagcacggtc atcaacatcg cgcttttgcc tgttttaatc cttggcatgt ttggttttcc
    16201 gaaactgggc atatacggct cggcatatgc aactgtcatt tccacgattg cgacttttct
    16261 cgtgttaatg gtgtatttac gaaagcgaaa acacccgctg caatttgata aaacagtgcg
    16321 tcgttatttg aaaatggata aggaactgct ggttctcctg ctgcgtcttg gggtcccagc
    16381 aagcatcaat atgattcttg tctcattatc agagatagcg gttatttcat tcgtcaatca
    16441 ttacggctct aatgcaacag ctgcatacgg agtggtcaac caggtggcca gctatgtaca
    16501 gatgccggcc gtcagccttg gtattgcggt ttctattttc gctgcgcaat cgattggggc
    16561 aaacgagttt gaccgcttaa agcaggtcat tcgcgtgggg atttggctga attatatcat
    16621 tggcggcgta ctgatcattc tgatctatgt tttttcacat cagattttgt cgttattttt
    16681 aaccgagcaa gagacgcttt acattgcaca ccgtcttttg atgattacat tgtggagtta
    16741 tttgctgttt ggaaatgccc aaattatttc tgcaacgatg cgggcaagcg gaacagtttt
    16801 atggccgacc gtcatcagta tttttgcaat ctggggagta gaggtgcctg tcgctttcgt
    16861 cctttctcac tatacaaagc ttgaaatact cggcgtctgg gttggttatc cagctgcgtt
    16921 tgccgtcagc ttgctgttga tttatgggta ttatcaattc gtctggaaaa agaaacaaat
    16981 cacacgtctc atccaatagc ctccgaatca caccgttcat aagtttgaac ggtgtttttt
    17041 tatttgatag gggaaaatat aaaatggagg aaatatggta cagtacattg aattcttata
    17101 ctagcaatga atcaaggaga ggttgagtaa acatggcaaa ctttattgag aaaatcacgt
    17161 atttgggaac gccggccatc aaagcgggca acgaacatct agaaatgatt gttgtccctg
    17221 agtgggggag caacgtcatt tctctcgtgg acaaaacaac aaatgtccag cttttgcgtg
    17281 aaccggaaac agcagaaagt tttcacgaca caccaacatt gtatggcatt ccaatcctgt
    17341 tcccgcctaa ccgcataagt gacggtacat tcagtttccg gggcagaacg tatcattttg
    17401 atatcaacga gaaggataaa cacaaccatc ttcatgggtt tctttaccat gaaaagtgga
    17461 atgtcgtgac cacgaagcaa actgatgaag gagtgattgt tgaaacagaa attgatcttt
    17521 ctgagcttcc ccatgtgcag aatcaatttc ctcatcatgc cgtcgttcgg atgacataca
    17581 cgatcaaggg gaatacccta tttaaacatg cgacggtcat gaacaaagga aaggaagcgt
    17641 ttccttgggg aattgggtat catactacat ttgtgtttcc ggcagaaagc tcgttattct
    17701 ccctgacagc agatcagcaa tgggagttgg atgaacgcct gctgccgacc gggaaactga
    17761 tggatgtacc gaataaagaa gctttgcatg aaggaatgga tttgcgccac aagcagctgg
    17821 atgatgtctt tttatcttcc tatcagaaga ggggcggaga aaaccaggca gtcatttatc
    17881 atcagcatgc acatatcagc attatttata aggcagatga acattttaac cattgggttg
    17941 tatacaatgc ggacggaaaa caagggtatt tatgccctga accttacaca tgggtgacaa
    18001 acgctgtgaa tcttgattta ccttcgtcac tcactggttt acaagtgctg gagccgggag
    18061 aagaaacgac agctaaaagc agtatcacca ttgaactgaa tcatcaatag ccaatgatga
    18121 agcgcagaga ggcggggaaa ttaatgaaaa aaagcataaa gctttatgtt gctgttttac
    18181 tgcttttcgt cgttgcttcg gtgccttata tgcatcaggc tgcgcttgcc gctgaaaaac
    18241 aagatgcact ttccgggcag atcgataaga ttttagctga tcatcctgcc ctcgaaggcg
    18301 caatggccgg catcaccgtt cgctctgcgg aaacaggtgc tgttctatat gaacattcag
    18361 gagacacccg aatgaggcct gcctcttctc taaagctttt gacagcggcc gcggcacttt
    18421 ctgtccttgg cgagaactat tcttttacaa ccgaggtccg gacggatgga acactgaaag
    18481 ggaaaaagct gaatggtaac ctttatttga aagggaaagg cgatccgaca cttttaccat
    18541 ctgattttga caaaatggct gagaaattga aacattccgg cgtaaaagta attaaaggca
    18601 atctgatcgg tgatgatacg tggcatgatg acatgcgatt atcacctgat atgccttgga
    18661 gcgatgaata cacatattat ggcgcgccaa tctccgctct aacagcgtct ccgaatgaag
    18721 actatgatgc aggcactgtg attgttgagg tcaccccaaa tcaaaaagaa ggggaagagc
    18781 ctgccgtgtc tgtctctccg aaaaccgatt atataacgat aaagaacgat gctaaaacga
    18841 ctgctgccgg ttcagagaaa gacctcacaa tcgaaagaga gcatggaaca aacacgatta
    18901 caattgaagg gagcgtaccg gttgacgcaa acaagacaaa ggaatggatt tctgtctggg
    18961 agcctgccgg atatgcctta gatttattta agcagtcact aaaaaaacaa ggaattactg
    19021 tgaaagggga catcaagacg ggtgaagcac ctagttcttc agatgtgctg ctctctcatc
    19081 gctcaatgcc tttatcgaaa ctttttgtgc cgttcatgaa attaagtaat aacggacatg
    19141 ccgaagtgct cgtaaaagag atggggaaag tgaaaaaagg agaagggagc tgggaaaagg
    19201 ggctcgaagt gttaaacagt acacttccag aatttggtgt tgattctaaa tcactcgtct
    19261 taagggacgg atcaggaatc tcacatattg atgctgtatc ctcagatcaa ctttcacagc
    19321 tgttatatga cattcaggat cagagttggt tctcggctta tctaaattca ttacctgttg
    19381 cgggcaaccc tgacagaatg gtgggcggaa cgctgagaaa ccgcatgaaa gacactcctg
    19441 cacaaggaaa agtaagagca aaaaccggat cgctcagtac ggtaagctct ctatcggggt
    19501 acgcagaaac aaagagcgga aaaaaacttg ttttctctat tcttctaaat ggattgattg
    19561 atgaagagga tggaaaagat attgaggatc aaatcgctgt cattttggca aatcaataat
    19621 agcggcagac ctgttttcca agagaaaaca ggttttttta tgtctgtaat aacgctttgt
    19681 cgaaccttcc aacaattaga agaatgatgc acaaaagaaa attagtccga ttaaaaagta
    19741 gtgtataaga ccttatgtaa aacaatactt ttatcacttt atatccggaa atttgataaa
    19801 aaaagaaacg aaaaataaag aaataatact atattcaaaa aaatgttata aaaatttaat
    19861 gttttttatt gtactttaaa aaatatccgt taatatagtg catatatgga ttatatagtc
    19921 atataatttc ttttattgtc atttttctgc ttttttctac attttcttat cctcttatta
    19981 tgagaactgg agggaatccg ttgagcgaac atacttattc tttaacccat gcccaaagga
    20041 gagtgtggtt taccgaactg ctggagccag ataccagcat ttgcaatctt acagcttgtg
    20101 tgaaattcaa aggcaatatt gagcttgata ctctagaggg agcgctgaat cattccatct
    20161 cccgcaacga cgccattaga tttcagctgt tagaaggaga agagcttgag ccgcgattgc
    20221 accttactga atataaatat tatccactta gaataattga tttttcaaat gttgaaatga
    20281 tagaaataga gcaatggatt caggatcaag cgagcattcc atttaaactg ttcaactcgc
    20341 ctctttatca attttacctc cttagaattg actctcatga agtttggcta tttgcgaaat
    20401 tccatcatat cataatggat ggaatctctt taaatgtgat gggaaatcaa attatagatc
    20461 tttatcaaaa aatgaaaaag aaagatcctt tacctgatca gccggaacct tcttacttga
    20521 gctacatcga aaaagagagt caatatctac aatctccgcg gtttgcaaag gaccgtttat
    20581 tttggacgca aacctttgag cacccgttgg aataccactc gttagccgac cagacgtcct
    20641 tacaaaaaca gagcacatct gcatccagag acaccatcat tctttcacct gatctagagc
    20701 aaacgattcg aatcttctgc gaagaacaca agatcaatat catttcctta tttatggctt
    20761 cattttacat atgcatcagc cgaatcactt ctaaaaaaga tcttgccatt ggcacctact
    20821 atggcaacag aggttcaaag gctgaaaaag aaatgctcgg catgttcgtt agttcccttc
    20881 caatcagaat aacggttgat cctgacacag attttctttc ctttgtccgc acaataggca
    20941 gggaacagct ttctgttatg cgtcatcaac ggtttcctta taatttgctt gtaaatgaat
    21001 taagaaatga acagaaggat ttacacaacc ttatcggtat atctatgcag tatcagccac
    21061 ttcagtggca taatgcagat gattttgact atgaaacagc gctttatttc agcggataca
    21121 ccgcgaacga gctttcagtt caaatacaag aacggataga caatggaacc attcaattaa
    21181 atttcgacta tcaaaatacc ttgttttctc ttgaggatat taaacgaata caatctcatt
    21241 tgcttaccat actggaaaac gcccttcaac atccgcacag ctttataaga gaattagata
    21301 tgacgaatac aagagaaaag caaaaattgt tgtatgagtt taacaggaca gtatctgttt
    21361 cacctaaagc tttcacccta catgggctgt ttgagcaaca ggcagcttcc acaccggagc
    21421 ggccagccat tcgcttttca ggcggttcgc tgacatacgc tgagcttgac atgtacgcca
    21481 gccggctggc tgcgcacctt gcggcacgcg gcgtcacaaa cgaaagtatc gtcggtgtcc
    21541 tgtctgaacg ctcacctgac atgctgatcg ctgtccttgc tgtattgaag gccggagggg
    21601 cgtatttgcc gcttgatcct gcgtatccaa aggagcggct gagctacatg ctgaaagaca
    21661 gcggggcatc gctcttgctg acacagccgg gatgctccgc accaaacttt tctggcgaaa
    21721 cgcttgaagt ggacatgaca tctcttgagt gtgaagaagt aaaacgtcat gtgtctgctt
    21781 ctgttagcga cggatctctc gcctatgtca tctatacatc gggctctacc gggcagccga
    21841 aaggagtggc cgttgagcac cgccaggctg tttcttttct gaccggcatg cagtaccagt
    21901 ttccgctttc ggaagatgac attgtcatgg tgaaaacctc tttttccttt gatgcgtctg
    21961 tgtggcagct gttttggtgg gctctttccg gtgcttcggc gtatctgctt ccgcccggct
    22021 gggaaaaaga ctccgcattg atcgtacaag ccattcatca ggaaaacgtg acaacggctc
    22081 attttattcc ggctatgctg aacagctttc tctatcaagc ggaaatcgaa aggctgagtg
    22141 acaggacaag cctaaagcgt gtattcgccg gaggtgaacc gcttgcgccg cgtacggcag
    22201 cccgttttgc ttctgtattg ccgcaggtat cattaatcca tggctacggg ccgacagaag
    22261 ccacggtaga cgcggcattt tacgtgttag atccagaacg ggacagagac cgtttgcgga
    22321 ttccgattgg gaagcccgta cctggtgcgc gtttgtatgt tttagatccg catttagccg
    22381 tacagccttc cggtgtcgcc ggcgaactat acattgccgg agcgggtgtt gccagaggtt
    22441 atttgaatcg gccggcatta acggaggagc gttttcttga agacccgttt tacccgggtg
    22501 aacgcatgta caaaaccggg gatgtggcgc gctggctccc tgacgggaat gttgaattcc
    22561 tcgggcgcac ggatgatcag gtgaaaatcc gcggctaccg gattgagccg ggagaaattg
    22621 aagcggcact aagaagtata gaaggtgtaa gagaggcggc cgttaccgta cggacagaca
    22681 gcggggagcc ggaattatgc gcttatgtag aagggctcca aagaaacgaa gtccgagcgc
    22741 agcttgagag actgttgccg ggctacatgg tcccagccta tatgatagag atggaacagt
    22801 ggccggttac gccaagcgga aagctcgacc gaaacgccct gccagctcct ggcggagcgg
    22861 cagatgcgga gacctacaca gcgccgagaa acgtgactga gatgaagctt tctcagctgt
    22921 gggaggacgt gctgaaaaat ggccctgtcg ggattcacga caactttttt gaccgcgggg
    22981 gacattcctt aaaagcaacg gcgcttgtct cacggatcac caaagaattc gatgtacagg
    23041 tgccgctaaa agatgtgttt gcccatccga cagtagaagg actggctacc gttatccgtg
    23101 aaggaacgga cagtccatat gaagcgatta agcccgctga aaaacaggaa acctatccgg
    23161 tttcctctgc ccaaaagcgg atttatgtcc ttcagcagct ggaggacgga gggacaggct
    23221 acaatatgcc ggctgtgtta gagctcgaag ggaagctcaa ccctgaaagg atggacagag
    23281 ctttccaaga gctgatcaag cgccacgagt cgcttcg
//
