LOCUS       NZ_CP031455            21074 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces olivoreticuli subsp. olivoreticuli strain ATCC 31159
            chromosome, complete genome.
ACCESSION   NZ_CP031455
VERSION     NZ_CP031455.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivoreticuli subsp. olivoreticuli
  ORGANISM  Streptomyces olivoreticuli subsp. olivoreticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Complete genome sequence of Streptomyces olivoreticuli ATCC 31159,
            producer of anticancer bestatin and diverse secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2018) Tianjin Key Laboratory of Food
            Biotechnology, College of Biotechnology and Food Science, Tianjin
            University of Commerce, NO.409 Guangrong Road, Tianjin, Tianjin
            300134, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-JUN-2018
            Assembly Method                   :: SMRT Link v. 5.1.0
            Assembly Name                     :: TJCU_BT_311
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: SMRT Link v5.1.0
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003391135.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 04:49:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,459
            Genes (coding)                    :: 7,276
            CDSs (with protein)               :: 7,276
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 183
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 183
            Pseudo Genes (frameshifted)       :: 61 of 183
            Pseudo Genes (incomplete)         :: 150 of 183
            Pseudo Genes (internal stop)      :: 18 of 183
            Pseudo Genes (multiple problems)  :: 41 of 183
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:12:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6629079
            Orig. end                         :: 6650153
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031455.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Hongyu Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="33"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            379..3282
                     /locus_tag="DXZ73_RS29490"
     CDS             379..3282
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025: diguanylate cyclase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014176153.1"
                     /locus_tag="DXZ73_RS29490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EAL domain-containing protein"
                     /protein_id="WP_162890374.1"
                     /transl_table=11
                     /translation="MSAPGAALSRRPAGGSGPASQLLLALVCGGYATGAAFGWGSSELA
                     SAMGDFGLGGAAALAAVSCFWYGRTHKTRFRLAWLLFAASSAMAGLGNIVWGWYEVVLD
                     ERVPTPSPADFCFLLFAPPAIIGLLVLARRPVTRAGWVCLALDAWLTGGSLLTLSWSLA
                     LAHTAHFQGETVAHAALSLAYPLLDIALVSMVLALHFRRSTANRSAINTAIAALALTVL
                     CDALFTSPLLRSHYRSGQILDAGWFAGYMLMAYAPWVAREEGDDTAVPARTVQHLHHPS
                     RPIAGSLAALTPYLAAAVCTLGILYNVLDGHHVDQVVLFTGCTVVLALVIRQGIMLLDN
                     ISLTQELAQKENHFRSLVQGSSDVIMIAAPTGILRYVSPAAAGVYGREAEELVGSELAS
                     LIHPEDLGRVVHEVRRFLAAPPAEEPTTRIECRFRSGTGDWLNVESTVNRHHGGLIFNS
                     RDVTERVRLQAQLQHTAEHDPLTDLPNRALFTKRVQQALAGRRATDAGTAVLFIDLDGF
                     KAVNDTVGHQAGDELLVQAARRLQDSVRSGDSTARFGGDEFAALIIGDGTRDPAAREYR
                     IHEIADRLRLTLSQPYRVEGGTEVRVAASIGVAFAEPGITPGSLMRNADLAMYRAKQAG
                     KGRVELYAPQMQADVVRRAELATRLRTALHDGEFALLHQPVVELQTGRVTAVAAQPRWR
                     SAQGILFTPAEYLRVAESERGDEAARSAELGRWTVEKAVEQAAHRCRAGHPVPVYVQLS
                     ATRLMDKSLPPKYLEGLLIHHGLPSGALVLELSGSDPRVPLDELERRLVTLRRLGVRIA
                     LDGFGSGYAAISALRRLPIDTLKLDRGLVDGVVESARLHKITAGLLRIATDLGMQSVAE
                     GVDVPEQALALRAMGCTHGLGKAFAGPLDEHRLRYALDLGSYPVPRSVDSANVLVGGAL
                     PAPAIMPSGARSGAAGGAGSLAHAPLRSNNETPVPPA"
     gene            3534..5396
                     /locus_tag="DXZ73_RS29495"
     CDS             3534..5396
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0003984 - acetolactate synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007457061.1"
                     /locus_tag="DXZ73_RS29495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetolactate synthase large subunit"
                     /protein_id="WP_116214046.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 7.6e-54, bitscore:
                     180.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 6.1e-49, bitscore:
                     164.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMTEQATGAHHPQPRARNGAAHQPATVEHVTGAQSLIRSLEEVG
                     AEIVFGIPGGAILPAYDPMMDSSKVRHVLVRHEQGAGHAATGYAQATGKVGVCMATSGP
                     GATNLVTPIADAHMDSVPLVAITGQVASKSIGTDAFQEADICGITMPITKHNWLVTDPA
                     EIPRTIAEAFHVASTGRPGPVLVDIAKDALQARTVFSWPPHTDLPGYRPVTKPHAKQIR
                     EAAKLITQAKRPVLYVGGGVMKSGATAELKVLAELTGAPVTTTLMALGSFPDSHPLHVG
                     MPGMHGAVAAVTALQKSDLIVALGARFDDRVTGRLDSFAPYAKIVHADIDPAEIGKNRA
                     ADVPIVGDAREVIADLIVAIQTEHAEGHAGDYSAWWADLNRWRDTYPLGYDQPEDGSLS
                     PQQVIQRIGQLAPPDTIYAAGVGQHQMWASHFIDYEQPRTWLNSGGAGTMGYAVPAAMG
                     AKAGAPDRTVWAIDGDGCFQMTNQELVTCALNDIPVKVAIINNGALGMVRQWQTLFYNQ
                     RYSNTVLHSGPESSGKEACAGTRVPDFVKLAEAMGCVGLRCEDPAQLDSVIEKANSIND
                     RPVVVDFIVHQDAMVWPMVAAGTSNDEILAARGVRPDFGDNEDD"
     gene            5419..5943
                     /gene="ilvN"
                     /locus_tag="DXZ73_RS29500"
     CDS             5419..5943
                     /EC_number="2.2.1.6"
                     /GO_function="GO:1990610 - acetolactate synthase regulator
                     activity [Evidence IEA]"
                     /GO_process="GO:0009082 - branched-chain amino acid
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ilvN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925060.1"
                     /locus_tag="DXZ73_RS29500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acetolactate synthase small subunit"
                     /protein_id="WP_116214047.1"
                     /transl_table=11
                     /translation="MTKHTLSVLVENTPGILTRIAALFARRGFNIDSLAVGVTEHPDIS
                     RITIVVNVESLPLEQVTKQLNKLVNVLKIVELEDSNAIQRELVLVKVRADNETRSQIVE
                     IVQLFRAKTVDVSPEAVTIEATGGSDKLGAMLKMLEPFGIKELVQSGTIAIGRGARSIT
                     DRSLRALDRTA"
     gene            6046..7044
                     /gene="ilvC"
                     /locus_tag="DXZ73_RS29505"
     CDS             6046..7044
                     /EC_number="1.1.1.86"
                     /codon_start=1
                     /gene="ilvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004948463.1"
                     /locus_tag="DXZ73_RS29505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ketol-acid reductoisomerase"
                     /protein_id="WP_116214048.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 9.5e-07, bitscore:
                     27.1, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAELFYDNDADLSIIQGRKVAVLGYGSQGHAHALSLRDSGVDVR
                     VGLHEGSKSKAKAEEQGLRVVTPAEAAAEADVIMILVPDPIQAKVYEESVKEHLKDGDA
                     LFFGHGFNIRFGFIKPPAGVDVCMVAPKGPGHLVRRQYEEGRGVPCIAAVEQDATGKAF
                     ALALSYAKAIGGTRAGVIRTTFTEETETDLFGEQAVLCGGASALVKAGFETLVEAGYQP
                     EIAYFECLHELKLIVDLMYEGGLEKMRWSVSETAEWGDYITGPRIVTEQTKAEMKKVLG
                     EIQDGTFATNWMKEYEAGLPKYNEYKKADEDHLLETTGKKLRKLMSWVDDK"
     gene            7262..8866
                     /gene="serA"
                     /locus_tag="DXZ73_RS29510"
     CDS             7262..8866
                     /EC_number="1.1.1.95"
                     /GO_function="GO:0004617 - phosphoglycerate dehydrogenase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006564 - L-serine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="serA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014176149.1"
                     /locus_tag="DXZ73_RS29510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="WP_116214049.1"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 4.6e-61, bitscore:
                     204.0, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTASSRKPVVLIAEELSPATVDALGPDFEIRHCNGADRAALLPA
                     IVDVDAVLVRSATKIDAEAIAAAKRLRVVARAGVGLDNVDVAAATKAGVMVVNAPTSNI
                     VTAAELACGLLIATARNIPQANSALKNGEWKRSKYTGVELSEKTLGVVGLGRIGVLVAQ
                     RMSAFGMKIVAYDPYVQPARAAQMGVKLLTLDELLEAADFITVHLPKTPETLGLIGDEA
                     LHKVKPSVRIVNAARGGIVDEAALATALKEGRVAAAGLDVYTQEPCTDSPLFEFDSVVA
                     TPHLGASTGEAQEKAGIAVAKSVRLALAGELVPDAVNVQGGVIAEDVKPGLPLAEKLGR
                     IFTALAGEVAVRLDVEVYGELTQHDVKVLELSALKGVFEDVVDETVSYVNAPLFAQERG
                     VEVRLTTSSESAEHRNVVTVRGTLSGGDEVSISGTLAGPKHLQKIVAVGEHDVDLALAD
                     HMAFLRYGDRPGVVGTVGRILGEAGINIAGMQVSRAREGGEALVALTVDESIPAPVLAE
                     IAEEIGAASARAVNLTD"
     gene            complement(8916..9995)
                     /locus_tag="DXZ73_RS29515"
     CDS             complement(8916..9995)
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039286.3"
                     /locus_tag="DXZ73_RS29515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_116214050.1"
                     /transl_table=11
                     /translation="MRKNSTARVHRFPDEARPGYRSGPPALPYPNGWFCAGFSDMWAPG
                     SVHTVPFMGEDLVVFRTARGTLKATRPYCPHLGAHLGVGGTVRDEELQCPFHHLRYSTN
                     GDCVHSPYGPAPDISLSMLPLREEWGIVWVWHHGENTGPTWELSAGLTGLEHARDPVYQ
                     ITDLGGYPQDVSENVVDYTHLTYLHGLIDLEVVVPPRYDGPFGRVTMRAGRRIGPVTAK
                     SEFLNQFPGLAGANINVEMREYGLYSVNWLLATPIGPGRMRYSLASSLEFLDHSDAPGP
                     VGALLSRKVLRLLQYPIFWQTRKDAARDLGVFHHKRFTAPPRLAGGDGPIGAHRKWSRQ
                     FYPTPDGQDPDAYFARAKL"
     gene            complement(10001..11074)
                     /locus_tag="DXZ73_RS29520"
     CDS             complement(10001..11074)
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="DXZ73_RS29520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="terpene synthase family protein"
                     /protein_id="WP_116214051.1"
                     /sec_met_domain="T1TS (E-value: 1.3e-58, bitscore: 198.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKPRLFDDTHGQDMAAMTRYEVPDYHMPWPVTLNPDHERAERAA
                     RKWATDFGLLDDDAARQRMIDMQCGLFSGWWCPRTDTHGAVLMAKWVAWLFLWDDIFDD
                     GPLGRDPEVFKDGKARLDLLLSQDPPPSPNAPGLAFPLARALADLWGDFYDYFPEHPRG
                     RFALHVKQYLSAMEKEVGNRSAEELPDTDAYLRLRVVNGATRPSIDVLEGLQGANIPDH
                     LHRGLFYELRDMAAELWLWSNDTFTVRKDLHYRNPHNLVLVLRQDRDLSLQSAAHHVAY
                     MTQQRLRDFRRIADRLRGLTDIADDPHARHKEDILRGVRVLEDALSGYYRWQETCLRYK
                     RKEGFLTPATTGPAQGR"
     misc_feature    complement(10490..10492)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11102..11809)
                     /gene="uppS"
                     /locus_tag="DXZ73_RS29525"
     CDS             complement(11102..11809)
                     /EC_number="2.5.1.-"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_process="GO:0009252 - peptidoglycan biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="uppS"
                     /inference="COORDINATES: protein motif:HMM:TIGR00055.1"
                     /locus_tag="DXZ73_RS29525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl diphosphate synthase"
                     /protein_id="WP_162890376.1"
                     /transl_table=11
                     /translation="MPALTAREPKLRHVAVILDGNRRWAQGRHVPLEQAYRQGALRVHD
                     LVTWCEQAQVCAVTVWALSQDNLQRRPQEVAQILNSVTHGLDRIVTATRWHIRLIGALD
                     RIPSHHAVRLRTLALRSAGANSAGTLTIAVAYDGRADIVTAIRSLLHERTPEERTAPID
                     ETAISRHLSTAGQPDIDLVIRTSGEQRLSGFMPWQTAHAELYFTDTLWPDFTRGDFDEA
                     RRWFAGRQRRHGS"
     misc_feature    complement(11983..11997)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    11984..11998
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 23.2"
                     /tool="antismash"
     gene            12160..12792
                     /locus_tag="DXZ73_RS29530"
     CDS             12160..12792
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602921.1"
                     /locus_tag="DXZ73_RS29530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_116214053.1"
                     /transl_table=11
                     /translation="MGHREDLLDGAKACMLEKGWVRTTARDIVAASGANLASIGYHYGS
                     KDALMMAAFVRMTEEWGAEMGRALEAGVPADASRAELLAARLDTLTAGFGNNRQFWELQ
                     LEVIGQLGSNPELKKWFAGVFPEGRQGMVSIFEGVDGCSASDEVVRTVGAFYHSLFVGM
                     WVQWAIDAESAPTGADVVEGMRRVLAGRLSGSPGSTGDTAADGGEGV"
     gene            complement(12873..13472)
                     /locus_tag="DXZ73_RS29535"
     CDS             complement(12873..13472)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941194.1"
                     /locus_tag="DXZ73_RS29535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_116214054.1"
                     /transl_table=11
                     /translation="MKTTTQAGTGAALGTRERIVRATSRLMQRQGYEGTGIKQISREAE
                     ATLGSVYHFFPGGKQELAAEAIRHGDREFAGILRSVLGAEEDPAQAVTDVARVVAEELR
                     ASDWVDGCPVTATSLGTAGRAPDIQRAAAEAFERWRGLVADKLRGCGIAEQDAYELAHT
                     VINTLEGAELAAQVARSEEPLLIAGRHLARLITSYR"
     misc_feature    complement(13531..13544)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.22"
                     /tool="antismash"
     gene            13562..14452
                     /locus_tag="DXZ73_RS29540"
     CDS             13562..14452
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941197.1"
                     /locus_tag="DXZ73_RS29540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_116214055.1"
                     /transl_table=11
                     /translation="MSFQASQDKQAVTVIGLGPMGTAMTEAFLAAGHRVTVWNRTAAKA
                     DALVAKGAERAATVEEALAANELVVLSLTDYDAMYAILGPATAALSGRVLVNLSSDTPA
                     RAREAAAWAESHGARHLTGGVQVPPSGIGSPGSSTFYSGPRDVFEAHRHTLQVLTGTDF
                     RGTDPGLAALYYQLMMDVFWTTMTGYLHAVTVADAHGITAEEFLPYASSIVASVPNFLT
                     FYTPRIDAGRHDGDVDNLAMGAASVDHVVHTTEDAGVDSSLPTAVLEIFHRGLDRGHAG
                     DSFTSLIGTFRKPVA"
     gene            14665..15879
                     /locus_tag="DXZ73_RS29545"
     CDS             14665..15879
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004978785.1"
                     /locus_tag="DXZ73_RS29545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_116214056.1"
                     /sec_met_domain="p450 (E-value: 4.7e-27, bitscore: 93.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDSGIRTLPPAAPVFPQDRTCPYRPPADYDRLIADGPLTRATLY
                     DGRQVWLVTGHAEARALLVDPRLSTDRQNPAFPVIAPSSERQGEIRLPVLGVDDPEHGR
                     QRRMLIPHFGLKRVTAMRPRIQQVVDGLLDTMLAEGPGADLVRAFALPVPSMVICDLLG
                     IPYADHAFFEDSSRAMLIAGTSDESMAAFDELRDYLEDLVDRRRAEPGEGLLDELVADR
                     LAAGELDRNEVALTALLLLVAGHETTSNMISLGTYSLLEHPDQLAALRADPALMPGAVE
                     ELLRFLSIADGLIRVATEDFEIGGRTVRAGDGVMIGTSLVNRDAAAYADPDALDVHRSA
                     RHHVAFGFGVHQCLGQNLARAEMEIALTTLFQRIPTLSPAVAPDEVPLKPGHSLQGLFA
                     FPVTW"
     gene            15915..16109
                     /locus_tag="DXZ73_RS29550"
     CDS             15915..16109
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573271.1"
                     /locus_tag="DXZ73_RS29550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin"
                     /protein_id="WP_116215945.1"
                     /transl_table=11
                     /translation="MRISIDSDLCVGSGQCALTAPGVFTQDDDGYGAVLPGREDGGGDP
                     LAREAARACPVGAVTVEED"
     gene            complement(16121..17368)
                     /locus_tag="DXZ73_RS29555"
     CDS             complement(16121..17368)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018838940.1"
                     /locus_tag="DXZ73_RS29555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_116214057.1"
                     /transl_table=11
                     /translation="MRGDYQQLVDEISAALGAPATLEDRDFGLIAFGAHDGDDDVELTM
                     DPVRTRSILQRRSTAAVRAWFEAFGIARAQAPLRIPPDPAAGVFKGRICLPVRHRGVVL
                     GYVWLLDDEHLAGLDLSVPFADPRLAQAMETAARIGALLAAEARAGAELGELLRELLTG
                     RPAGRDAARAALREALGPAGDGPLAVVAVAPWRAAGDADGETGEAGDTEGTAAGSALAG
                     QSGVAALCAVPDALPDGSAALAALIRLRATTSPAPAHTAADRLLRSPRAGGAPGRPVRA
                     TAGLGTPRRGLAELPAAWREALAAARAAGAEARLGPVAEWSGIGPYRVLSALPAEAAAD
                     PSIRPLLAPAHTELARTAEVFLDCAGQAGRTAAALGIHRQTLYYRLSRVEQLTGLDLDD
                     GEGRLLLHMALKADRL"
     misc_feature    complement(17539..17552)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.02"
                     /tool="antismash"
     gene            17601..18527
                     /locus_tag="DXZ73_RS29560"
     CDS             17601..18527
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960086.1"
                     /locus_tag="DXZ73_RS29560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="proline dehydrogenase family protein"
                     /protein_id="WP_116214058.1"
                     /transl_table=11
                     /translation="MLGPVLLAASRSDAIRRLVSAAPGTKQVVARFIAGETLDQVIPIV
                     KDAAAEGLEVTLDVVGEDITTVEQSYAARDAYLELIGRLEELGLGARAEMSVKLSMFGQ
                     ALEGGHELALANVRPVVEAAAAIGTTVTLDAEDHTTLDSMFAIHEELRRDFPQTGCVIQ
                     AYLFRTEDDARRLAAAGSRVRIVKGAYKEPASVAYQDKAEIDKAFVRIVKILMAGEGYP
                     MIGSHDPRLIAISQELARQAGRKLDEYEFQMLYGIRSEEHVRLAAEGHRMRVYTAYGTD
                     WYGYFMRRLAEKPANLLFFARSILTKG"
     gene            18573..20204
                     /gene="pruA"
                     /locus_tag="DXZ73_RS29565"
     CDS             18573..20204
                     /EC_number="1.2.1.88"
                     /GO_function="GO:0003842 - 1-pyrroline-5-carboxylate
                     dehydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006562 - proline catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pruA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005311510.1"
                     /locus_tag="DXZ73_RS29565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="L-glutamate gamma-semialdehyde dehydrogenase"
                     /protein_id="WP_116214059.1"
                     /sec_met_domain="Aldedh (E-value: 9.2e-101, bitscore:
                     336.4, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDAVTQVPAPVNEPVHSYAPGSPERARLEAKLKELAGNPIDLPMT
                     INGEKRMGGGEPFKVVQPHNHAAVLGTFNNATRQDAQDAVDTALAAAPAWRAMSFDDRA
                     AIILRAAELLAGPWRETLAASTMLGQSKTAQQAEIDTPCELVDFWRFNVHFARQILAEQ
                     PVANSTGVWNRSDHRPLEGFVYAITPFNFTAIAGNLPTAPALMGNVVVWKPSPTQTHSA
                     VLLMQLLEEAGLPKGVINLVTGDGIAVSEVALNHPELAGIHFTGSTKTFQYLWKTVGNN
                     IENYRSYPRLVGETGGKDFVVAHPSADRAILKTALTRGSFEFQGQKCSASSRAYIPRSI
                     WEDGFKEEFAAEVDGITMGDVTDLSNFIGAVIDDRSFAKNKAAIDRAKADPSCTVVAGG
                     TYDDSVGYFVRPTVIECTDPANEVFTTEYFGPILAVHVYEDGDFDAMLAQMESVSAYAL
                     TGAVIAQDRAAAADAMEKLRFAAGNFYINDKSTGAVVGQQPFGGGRASGTNDKAGAASN
                     LMRWTSTRSIKETLVPPTDYRYPHMG"
     gene            20520..20663
                     /locus_tag="DXZ73_RS38440"
     CDS             20520..20663
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960091.1"
                     /locus_tag="DXZ73_RS38440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_162890377.1"
                     /transl_table=11
                     /translation="MPETAVRRIRRAPRPAESADRRTDRMNAAAALQRALDRRDNGGET
                     GH"
ORIGIN
        1 ccacgtagag gtaccgttcg gctgcactca gtgttcataa ccccgttgct gattacgcta
       61 tgtatatgag ctatgtccct gagtgacgag tctggtgtat cgtccggacc gggggctgcg
      121 ccgggcaccg tacggcgcag cgaagtaccg gcactgaggg gggcgacggg cgatgcacgg
      181 ccactggacg atcaacccga cgcggctcac gcaccgacca cgacagcgcg gcgcggcggt
      241 tccgccgacg cggctggccc gacttccctg gctgttccgc ctccggccca ggccgggcag
      301 tccggggcgg cgtccccatc tctccgtcct ccgggcccac ttcgcctggc tcggggtctc
      361 gcccgggacg gcggcgcggt gagcgccccc ggagcggcgc tgtcccgtcg gccggccggc
      421 ggttccgggc cggcgtccca gctcctcctc gccctcgtct gcggcggcta cgcgacgggc
      481 gcggccttcg gctggggatc gagcgagctg gcctccgcca tgggcgactt cggcctcggc
      541 ggcgccgctg ccctcgcggc cgtctcctgc ttctggtacg ggcggacgca caagacgcgc
      601 ttccggctcg cctggctgct cttcgcggcc tcctcggcga tggccggcct cggcaacatc
      661 gtctgggggt ggtacgaggt cgtcctcgac gagcgcgtac ccaccccgtc accggccgac
      721 ttctgcttcc tgctcttcgc gccgccggcc atcatcggcc tgctcgtcct cgccaggcgc
      781 cccgtcaccc gcgccggctg ggtctgcctg gccctcgacg cgtggctgac cggcggctcc
      841 ctgctgaccc tgtcctggag cctggcgctc gcgcacaccg cgcacttcca gggcgagacc
      901 gtggcgcacg ccgccctctc gctcgcctat ccgctgctgg acatcgccct ggtgtcgatg
      961 gtcctcgcgc tgcacttccg gcgctccacc gccaaccgct ccgccatcaa caccgccatc
     1021 gcggccctcg cgctgaccgt cctgtgcgac gcgctgttca cctcgccgct gctgcgctcg
     1081 cactaccgct ccggccagat cctcgacgcc ggctggttcg cgggctacat gctcatggcg
     1141 tacgccccct gggtggcccg ggaggagggt gacgacaccg cggtgcccgc ccgcaccgtc
     1201 cagcacctgc accaccccag ccggcccatc gccggctcgc tcgccgccct caccccttat
     1261 ctcgcggccg ccgtctgcac cctggggatc ctctacaacg tcctggacgg ccaccacgtc
     1321 gaccaggtcg tgctcttcac cggctgcacg gtggtcctcg cgctcgtcat ccgtcagggc
     1381 atcatgctgc tcgacaacat ctcgctcacc caggaactgg cccagaagga gaaccacttc
     1441 aggtccctgg tccagggctc cagcgacgtc atcatgatcg ccgcacccac cgggatactg
     1501 cgctacgtca gccccgccgc cgcgggcgtc tacggccgcg aggccgagga gctcgtgggg
     1561 tccgaactgg cctcgctgat ccacccggag gacctcggca gagtcgtcca cgaagtgcgc
     1621 cgcttcctcg cggcaccacc cgccgaggag cccaccaccc ggatcgagtg ccgcttccgc
     1681 tccggcaccg gcgactggct caatgtcgag tccaccgtca accgccacca cggcggcctc
     1741 atcttcaaca gccgtgatgt caccgagcgg gtccggctgc aggcccagct ccagcacacc
     1801 gccgagcacg acccgctcac cgacctgccc aaccgcgccc tgttcaccaa gcgggtccag
     1861 caggccctcg ccggccgcag agcgaccgac gccgggaccg cggtgctctt catcgacctc
     1921 gacggcttca aggcggtgaa cgacaccgtc ggccaccaag ccggcgacga gctgctggtc
     1981 caggcggccc gtcgcctcca ggactcggtg cggtccggcg acagcaccgc ccggttcgga
     2041 ggcgacgagt tcgccgcgct catcatcggc gacggcaccc gcgacccagc ggcgcgcgaa
     2101 taccgcatcc acgagatcgc cgaccggctc cggctcaccc tctcccagcc gtacagggtg
     2161 gaaggaggca ccgaggtccg cgtggccgca agcatcggcg tggccttcgc ggagcccggc
     2221 atcacccccg gctccctgat gcgcaacgcc gacctcgcga tgtaccgcgc gaagcaggcg
     2281 ggcaagggcc gcgtcgagct ctacgcaccg cagatgcagg ccgacgtggt gcgccgcgcc
     2341 gagctggcca cccggctgcg caccgcgctg cacgacggcg agttcgcgct gctccatcag
     2401 ccggtggtgg agctccagac cggccgggtc accgccgtcg ccgcgcagcc gcgctggcgc
     2461 tcggcccagg ggatactgtt cacccccgcc gagtacctcc gcgtggccga gagcgagcgc
     2521 ggcgacgagg ccgcgcgctc ggccgaactc ggccgctgga cggtcgagaa ggccgtcgag
     2581 caggccgccc accgctgccg cgccggccac cccgtgccgg tgtacgtcca gctgtcggcc
     2641 acccgtctga tggacaagtc gctgcccccg aagtacctcg aagggctgct catccaccac
     2701 ggcctgccct ccggcgcgct cgtcctggag ctgtccggca gcgaccccag ggtcccgctg
     2761 gacgagctgg agcggcggct ggtgaccctg cgccggctcg gcgtccggat cgccctcgac
     2821 ggcttcggca gcggctacgc ggcgatcagc gcgctgcgca ggctccccat cgacacgctc
     2881 aagctcgacc gcgggctggt cgacggcgtg gtggagtccg cccggctgca caagatcacc
     2941 gcggggctgc tgaggatcgc caccgacctc gggatgcagt ccgtggccga gggggtggac
     3001 gtgcccgagc aggccctcgc cctgcgcgcc atgggctgca cccacggcct gggcaaggcc
     3061 ttcgcgggcc cgctcgacga gcaccggctg cgctacgctc tcgatctcgg cagctatccg
     3121 gtgccccgct ccgtcgacag cgcgaatgtg ctcgtcggag gcgcgctgcc ggccccggcg
     3181 atcatgccgt cgggcgcccg ttcgggggcc gcgggcggcg cgggatccct cgcgcatgct
     3241 ccattgcgct caaataatga gacgcccgtc ccacccgctt gacacctcgt gggcggcggg
     3301 tggagggtcg gagccatgcg cacccgaatt ctcgtacttg gaaagcgcgt cggctgaagc
     3361 aggccaccca gtaagtcctg ctgaccactc cggcgcgctc ccctcgcttg cctcacggca
     3421 cgaggggttt tttgttgcac cggatgcacg cagacccgcc caaacctccc gtcctccgaa
     3481 gctgtcgaag tcgaaaccgt cgaatcctta ccgtcgaatc cttcgagaag agaatgtcga
     3541 tgaccgagca ggccaccggg gcccaccatc cgcagccgcg ggcccgaaac ggcgcggcgc
     3601 accagcccgc caccgtcgag cacgtcacgg gggcgcagtc cctcatccgc tcgctggagg
     3661 aggtaggggc ggagatcgtc ttcggcatcc cgggcggtgc gatcctcccc gcgtacgacc
     3721 cgatgatgga ctcctcgaag gtccgccacg tgctcgtccg gcacgagcag ggcgccgggc
     3781 acgcggccac cgggtacgcg caggccaccg gcaaggtcgg ggtgtgcatg gcgacctccg
     3841 ggccgggggc gaccaacctc gtcaccccca tcgccgacgc ccacatggac tccgtcccgc
     3901 tggtggccat caccggccag gtcgcctcca agtcgatcgg cacggacgcc ttccaggagg
     3961 cggacatctg cggcatcacc atgccgatca ccaagcacaa ctggctggtc accgaccccg
     4021 cggagatccc gcggaccatc gcggaggcct tccacgtcgc ctccaccggc cgccccggcc
     4081 cggtcctcgt cgacatcgcc aaggacgccc tccaggcgcg gaccgtcttc agctggcccc
     4141 cgcacaccga cctgcccggc taccgcccgg tcaccaagcc gcacgccaag cagatccgcg
     4201 aggccgccaa gctgatcacc caggccaagc ggccggtgct ctacgtcggc ggcggggtga
     4261 tgaagtccgg tgccaccgcc gagctcaagg tgctcgccga gctcaccggc gcccccgtca
     4321 ccaccaccct gatggcgctg ggctccttcc ccgacagcca cccgctccac gtcggcatgc
     4381 ccggcatgca cggcgcggtc gccgccgtca ccgccctgca gaagtccgac ctgatcgtgg
     4441 ccctcggcgc ccgcttcgac gaccgggtca ccggcaggct cgactccttc gccccgtacg
     4501 ccaagatcgt ccacgcggac atcgaccccg ccgagatcgg caagaaccgc gccgccgacg
     4561 tgccgatcgt cggggacgcc cgcgaggtca tcgccgacct gatcgtcgcc atccagaccg
     4621 agcacgccga gggccacgcc ggtgactaca gcgcctggtg ggccgacctc aaccgctggc
     4681 gcgacaccta ccccctcggc tacgaccagc ccgaggacgg cagcctctcc ccgcagcagg
     4741 tcatccagcg catcgggcag ctcgccccgc cggacacgat ctacgcggcg ggcgtcggcc
     4801 agcaccagat gtgggcctcg cacttcatcg actacgaaca gccccgcacc tggctcaact
     4861 ccggtggcgc gggcaccatg ggctacgccg tgcccgccgc gatgggtgcc aaggccggcg
     4921 cccccgaccg cacggtctgg gccatcgacg gcgacggctg cttccagatg accaatcagg
     4981 aactggtcac ctgcgcgctg aacgacatcc ccgtcaaggt cgccatcatc aacaacggcg
     5041 ccctcggcat ggtccgccag tggcagacgc tcttctacaa ccagcgctac tccaacaccg
     5101 tcctgcactc cggaccggag tcgagcggca aggaggcctg cgccggcacc agggtcccgg
     5161 acttcgtcaa gctcgccgag gccatgggct gtgtgggcct gcgctgcgag gacccggccc
     5221 agctcgactc cgtcatcgag aaggccaact ccatcaacga ccgcccggtc gtggtggact
     5281 tcatcgtcca ccaggacgcc atggtctggc cgatggtcgc cgccggaacc tccaacgacg
     5341 agatcctcgc ggcgcgcggt gtccgcccgg acttcggcga caacgaagac gactgaagcc
     5401 aggagaggca aagaaaccat gaccaagcac acgctctccg tcctcgtgga gaacaccccc
     5461 ggcatcctga cccggatcgc cgccctgttc gcccgccgcg gcttcaacat cgactcgctc
     5521 gccgtcggcg tcaccgaaca ccccgacatc tcccgcatca ccatcgtcgt caacgtcgag
     5581 tcgctgccgc tggagcaggt caccaagcag ctcaacaagc tcgtcaacgt gctgaagatc
     5641 gtggagctgg aggacagcaa cgcgatccag cgcgagctgg tcctggtgaa ggtccgcgcc
     5701 gacaacgaga cccgctccca gatcgtcgag atcgtccagc tcttccgcgc caagaccgtc
     5761 gacgtctccc cggaggccgt caccatcgag gccaccggcg gcagcgacaa gctgggcgcg
     5821 atgctcaaga tgctggagcc gttcggcatc aaggagctgg tgcagtccgg gacgatcgcc
     5881 atagggcgcg gcgcccgctc catcaccgac cgcagcctgc gcgccctgga ccgcacggcc
     5941 tgacggcccg accttccgca taacgagacc cgacgacatt tccccgcccg cccgtcatac
     6001 ggtgggacgc acaaccggaa acccggaaaa caaggagata cctcagtggc tgccgagctg
     6061 ttctacgaca acgacgccga cctgtccatc atccagggcc gcaaggtcgc ggtcctgggc
     6121 tacggcagcc agggccacgc ccacgcgctg tcgctgcgcg actccggcgt cgatgtccgg
     6181 gtgggcctgc acgagggctc caagtccaag gcgaaggccg aggagcaggg cctgcgcgtg
     6241 gtcacgcccg ccgaggccgc ggccgaggcc gacgtcatca tgatcctggt gccggacccg
     6301 atccaggcca aggtctacga ggagtccgtc aaggagcacc tgaaggacgg cgacgcgctg
     6361 ttcttcggcc acggcttcaa catccgcttc ggcttcatca agcccccggc cggcgtggac
     6421 gtctgcatgg tcgcccccaa gggcccgggc cacctggtgc gccgtcagta cgaggagggc
     6481 cgcggcgtgc cgtgcatcgc ggccgtcgag caggacgcca ccggcaaggc cttcgcgctg
     6541 gcgctctcct acgccaaggc gatcggcggc acccgcgccg gcgtcatcag gaccaccttc
     6601 accgaggaga ccgagaccga cctcttcggc gagcaggccg tgctctgcgg cggtgcgtcg
     6661 gcgctggtca aggccggttt cgagaccctg gtcgaggcgg gttaccagcc ggagatcgcg
     6721 tacttcgagt gcctccacga gctcaagctg atcgtggacc tgatgtacga gggcggcctg
     6781 gagaagatgc gctggtcggt ctccgagacc gccgagtggg gcgactacat caccggcccc
     6841 cgcatcgtca ccgagcagac gaaggccgag atgaagaagg tcctgggcga gatccaggac
     6901 ggcaccttcg ccaccaactg gatgaaggag tacgaggcgg gcctgccgaa gtacaacgag
     6961 tacaagaagg ccgacgagga ccacctgctg gagaccaccg gcaagaagct ccgcaagctg
     7021 atgagctggg tcgacgacaa gtaggccgtt tccggcgcgg ggacccgggg gcgcgttccc
     7081 cgggtccccg cgccgtactc cggggtgacg ttcacccgta cgcacccgac ccggggtcca
     7141 acccccgata cactgccaac cacaaacgcg tcaggctcac agcgtcgtgc gtcacacgcg
     7201 gctgcccttc accgccttcg gccgtcggga cggccgtccg caaaggacta gtgaggacca
     7261 cgtgagcaca gcttcgtccc gtaaacccgt cgtactgatc gcggaggagc tctcgcccgc
     7321 gaccgtcgac gccctgggtc cggacttcga gatccggcac tgcaacggcg cggaccgcgc
     7381 cgccctgctg cccgccatcg tcgatgtgga cgccgtcctc gtccgcagcg ccacgaagat
     7441 cgacgccgag gcgatcgcgg ccgccaagcg gctgcgggtc gtcgcgcgcg ccggtgtcgg
     7501 tctggacaac gtcgacgtcg ccgccgcgac caaggccggc gtgatggtcg tgaacgcccc
     7561 gacctccaac atcgtcaccg ccgccgagct cgcgtgcggc ctgctgatcg ccaccgcccg
     7621 caacatcccg caggccaact cggcgctgaa gaacggcgag tggaagcgtt cgaagtacac
     7681 cggcgtcgag ctgtccgaga agaccctcgg cgtcgtcggt ctcggccgca tcggggtgct
     7741 cgtcgcccag cgcatgtccg cgttcggcat gaagatcgtc gcctacgacc cctatgtgca
     7801 gcccgcgcgg gccgcgcaga tgggggtgaa gctgctgacg ctggacgagc tgctggaggc
     7861 cgcggacttc atcaccgtcc acctgcccaa gacccccgag acgctcggcc tcatcggcga
     7921 cgaggcgctg cacaaggtca agccgtcggt gcggatcgtc aacgccgcgc gcggcgggat
     7981 cgtggacgag gcggcgctgg ccacggcgct gaaggagggc cgggtcgcgg ccgcgggcct
     8041 ggacgtctac acccaggagc cgtgcacgga ctccccgctg ttcgagttcg acagcgtggt
     8101 cgccaccccg cacctgggcg cctccacggg cgaggcgcag gagaaggcgg gcatcgcggt
     8161 cgcgaagtcg gtccggctcg cgctggccgg cgagctggtg ccggacgcgg tcaacgtcca
     8221 gggcggtgtc atcgccgagg acgtcaagcc gggtctgccg ctcgccgaga agctcggccg
     8281 catcttcacc gcgctcgcgg gcgaggtcgc ggtgcggctc gacgtcgagg tgtacggcga
     8341 gctcacccag cacgacgtca aggtgctcga actgtccgcg ctcaagggcg tgttcgagga
     8401 tgtcgtcgac gagaccgtgt cgtacgtcaa cgccccgctg ttcgcgcagg agcggggtgt
     8461 cgaggtccgc ctgaccacca gctcggagtc ggccgaacac cgcaacgtgg tcaccgtgcg
     8521 cggcaccctg tcgggcggcg acgaggtctc gatctccggc acgctcgcgg gccccaagca
     8581 cctccagaag atcgtcgcgg tcggtgagca cgacgtggac ctggcgctcg ccgaccacat
     8641 ggcgttcctg cgctacggcg accgccccgg tgtcgtcggc acggtcggcc ggatcctggg
     8701 cgaggcgggc atcaacatcg ccggcatgca ggtctcccgg gcgcgggagg gcggcgaggc
     8761 cctggtcgcc ctgaccgtcg acgaatccat cccggcaccg gtcctcgccg agatcgccga
     8821 ggagatcggc gcggcgtcgg cgcgcgcggt gaatctgacc gactgagtca gggcaccgga
     8881 cgggccggac ccgcgggtcc ggcccgtccc gcatttcaga gcttggcccg tgcgaaatag
     8941 gcgtcaggat cctggccgtc aggggtgggg tagaactgac gggaccactt gcggtgggct
     9001 ccgatggggc cgtcgccgcc ggcgagcctg ggcggcgcgg tgaatcgttt gtggtgaaac
     9061 actccgaggt cgcgggccgc gtccttcctg gtctgccaga agatggggta ctggagcagc
     9121 cgcagcacct tccgggagag cagcgcgccg accggtccgg gcgcgtcgga gtgatcgagg
     9181 aattccaggc tggacgcgag gctgtagcgc atgcggccgg ggcctatggg cgtggcgagc
     9241 agccaattga cggagtagag gccgtattcg cgcatttcca cgttgatgtt ggcgccggcg
     9301 agtcctggga actggttgag gaactcggac ttcgcggtga ccgggccgat cctgcgacct
     9361 gccctcatcg tcacccggcc gaaggggccg tcgtaccgcg ggggcaccac gacttccagg
     9421 tcgatcagcc cgtgcaggta cgtgaggtgg gtgtagtcga cgacgttctc cgagacgtcc
     9481 tggggatatc cgccgagatc ggtgatctga tagacggggt cgcgggcgtg ttcgagcccg
     9541 gtgaggccgg cggacagctc ccaggtcggg cccgtgttct cgccatggtg ccagacccag
     9601 acgatccccc attcctcccg cagcgggagc atggacaggg agatgtccgg agcgggcccg
     9661 taggggctgt ggacacaatc cccgttcgtc gaatagcgga gatggtggaa ggggcactgc
     9721 agttcctcgt cccgcactgt gccgccgact ccgaggtgtg cgccgaggtg ggggcagtac
     9781 gggcgggtgg ctttgagggt gccccgcgcg gtgcggaaca cgacgaggtc ctcgcccatg
     9841 aaggggacgg tgtggacgct cccgggtgcc cacatgtcgg agaatcccgc gcagaaccat
     9901 ccgttgggat aaggcagggc gggagggccg ctccggtacc cgggtcgggc ctcatcgggg
     9961 aatcgatgga ctcgcgcagt cgaattcttg cgcattcttg tcaccttcct tgggccgggc
    10021 cggtggtggc gggagtgaga aacccttcct tgcgcttgta ccgcaggcac gtctcctgcc
    10081 agcggtagta gccggacagc gcgtcctcga gaacccggac gccacgcagg atgtcctcct
    10141 tgtgcctggc gtgcgggtca tcggcgatat cggtgaggcc gcgcaacctg tcggcgatcc
    10201 tgcggaagtc acgcagacgc tgctgggtca tgtacgcgac gtgatgtgct gccgactgaa
    10261 ggctgaggtc ccggtcctgg cgcaggacga gaacgaggtt gtgggggttg cggtaatgca
    10321 ggtccttgcg gacggtgaac gtgtcattgg accagagcca cagttcggct gccatgtcgc
    10381 ggagttcgta gaagaggccc cggtggaggt ggtcgggaat gttggcgccc tggagccctt
    10441 ccaggacgtc gatgctgggc cgggtggctc cgttgaccac gcgcagacgt aagtaggcgt
    10501 ccgtgtccgg gagttcctcc gcggaccggt tgccgacctc tttttccatg gcgctcagat
    10561 actgcttgac gtgcagcgcg aagcggccgc gcgggtgttc ggggaaatag tcgtagaagt
    10621 cgccccacag atcggccagg gcgcgggcca gcgggaaggc gagtccgggg gcgttcggtg
    10681 acgggggcgg atcctggctc aggagcaggt cgagccgggc tttgccgtcc ttgaacacct
    10741 cggggtccct gccgagcggc ccgtcgtcga agatgtcgtc ccacaggaac agccaggcga
    10801 cccacttggc catgagaacg gcgccgtggg tgtcggtacg cgggcaccac cagccggaga
    10861 acaggccgca ctgcatgtcg atcatgcgct gccgggccgc gtcgtcgtcc agcaggccga
    10921 agtccgtcgc ccacttccgg gccgcccgct cggcccgttc gtgatccgga ttgagggtga
    10981 cgggccacgg catgtggtag tcggggacct cgtaccgggt catggctgcc atgtcctggc
    11041 cgtgggtgtc atcgaacagc ctgggcttgg gcacgtctct tctcctggtg ggatgcgggt
    11101 gctagctccc gtggcggcgc tgtcggccgg cgaaccaccg tctggcctcg tcgaagtcgc
    11161 cgcgggtgaa gtcgggccag agggtgtcgg tgaagtacaa ctcggcgtgg gcggtctgcc
    11221 agggcatgaa cccggagagg cgctgttcgc cggaggtgcg gatgacgagg tcgatgtcgg
    11281 gctggccggc ggtggagagg tgccgggaga tggctgtttc gtcgatcggg gcggtgcgct
    11341 cttccggggt gcgctcgtgg agcagggacc ggatcgcggt gacgatgtcg gcgcgtccgt
    11401 cgtaggcgac ggcgatggtg agggtgcccg cgctgttcgc tccggcggac cgcagagcga
    11461 gggtgcgcag ccggacggcg tggtgggagg ggatccggtc gagggccccg atgaggcgga
    11521 tgtgccaccg ggtggcggtg acgatcctgt cgagcccgtg ggtgacgctg ttcaggatct
    11581 gcgcgacctc ctgtgggcgg cgctgaaggt tgtcctggga cagggcccag accgtgaccg
    11641 cgcagacctg ggcctgttcg caccaggtca ccaagtcgtg gacgcgcagg gccccttggc
    11701 gataagcctg ctccagcggc acgtggcggc cctgggccca ccggcggttc ccgtccagga
    11761 tcacggcgac atggcgcagt ttcggctctc gagcggtcag tgccggcatg gttctcccgg
    11821 ctcgggcgca tccaggtccg ggatgacatg gcccacagtt caacctcccc cgactccctg
    11881 atgtattccg cagggaccga ggcgtatacc gcgtcagggg ggcgcgtgga tcgaaccgag
    11941 gcacttgact gttgtgcgca cgcagacatg gacacgccat ccctgggcgc gctccgatgc
    12001 gcccgtgccg ggggtggtcg gggtgctcac aggccacggt cgtgtcgctc atgcgaatcc
    12061 cacgtcggac gtcgccgcgg tggctccgaa cgatggtctg gaactttgta taagacgagc
    12121 gtctagtaca cgcgtatggc ccggcactag gctgctgaca tgggacatcg cgaagacctg
    12181 ctcgacggtg cgaaggcctg catgctcgaa aagggctggg tgcgcaccac cgcgcgcgac
    12241 atcgtggccg cctccggcgc caacctcgcc tcgatcggct accactacgg ctccaaggac
    12301 gcgctgatga tggcggcgtt cgtgaggatg accgaggagt ggggtgccga gatgggccgc
    12361 gccctggagg ccggtgtgcc ggcggacgcc tcgcgtgcgg agctcctcgc ggcgaggctg
    12421 gacacgctga ccgcggggtt cgggaacaac cggcagttct gggagctcca gctggaggtg
    12481 atcggccagt tggggagcaa cccggagctc aagaagtggt tcgccggggt cttcccggaa
    12541 ggccggcaag gcatggtgtc gatcttcgag ggtgtcgacg gctgttccgc gagcgacgag
    12601 gtggtgcgca ccgtgggtgc cttctaccac tccctcttcg tcgggatgtg ggtccagtgg
    12661 gccatagacg ccgaatccgc gccgaccggc gcggatgtgg tcgaggggat gcgccgggtg
    12721 ctggcgggcc ggctctccgg gtcgcccggg tccaccggcg atacggcggc ggacggcggc
    12781 gagggtgtct gacgggtccg gcgccccgcg ggcgtcggac ccctccgctc atcgatagct
    12841 catcgacagc ccatcgaagg ctcatcggca gctcaccgat aggaagtgat cagccgggcc
    12901 agatgccgcc cggcgatcag cagcggctcc tcgctccgcg cgacctgggc cgccagctcc
    12961 gcgccctcca gcgtgttgat caccgtgtgc gcgagctcgt aggcgtcctg ctcggcgatc
    13021 ccgcagccac ggagcttgtc ggccaccagc ccccgccagc gctcgaacgc ctccgccgcc
    13081 gcccgctgga tatcgggcgc gcgcccggcc gtccccaggc tcgtcgccgt gaccgggcag
    13141 ccgtcgaccc agtcggaggc gcgcagctcc tcggcgacga cgcgggccac gtcggtcacc
    13201 gcctgtgccg gatcctcctc ggcgcccagc accgaccgca ggatgccggc gaactcccgg
    13261 tcgccgtggc ggatcgcctc cgccgccagc tcctgcttgc cacccgggaa gaagtggtag
    13321 accgagccga gcgtggcctc ggcctcccgg gagatctgct tgatcccggt cccctcgtag
    13381 ccctgacgct gcatcagccg tgatgtcgcc cggacgatcc gttcgcgcgt gccgagggcg
    13441 gcgcccgtgc ctgcctgcgt agtggtcttc accccgcaag gataccgaat agagcgttcg
    13501 ttccagaggc gtgctaggtt cctcctggat ggagcgttcg ttctagcgag ggggatctcc
    13561 catgtctttt caggcttccc aggacaagca ggccgtcacc gtcatcggtc tcggccccat
    13621 gggcacggcg atgaccgagg cgttcctggc cgccggccac cgggtgaccg tgtggaaccg
    13681 cacggccgcc aaggccgacg ccctcgtcgc caagggcgcc gagcgggcgg ccacggtcga
    13741 ggaggcgctg gccgccaacg agttggtggt cctcagcctg accgactacg acgcgatgta
    13801 cgcgatcctc ggtcccgcca ccgcggcgct gtccggccgg gtcctcgtca acctcagctc
    13861 cgacaccccg gcgcgcgccc gcgaggccgc cgcgtgggcc gagagccacg gcgcgcgcca
    13921 cctcaccggc ggggtgcagg tgccgccctc gggcatcggc tcgccggggt cgtccacctt
    13981 ctacagcggc ccccgggacg tcttcgaggc ccaccggcac accctccagg tgctcaccgg
    14041 caccgacttc cgcggcaccg acccgggcct ggccgcgctg tactaccagc tcatgatgga
    14101 cgtcttctgg accacgatga ccggctacct gcacgccgtc accgtcgccg acgcccacgg
    14161 catcaccgcc gaggagttcc tgccgtacgc gagctcgatc gtggcgtcgg tcccgaactt
    14221 cctcacgttc tacaccccgc gcatcgacgc cgggcggcac gacggcgacg tcgacaacct
    14281 cgccatgggc gccgccagtg tcgaccacgt cgtgcacacc accgaggacg cgggcgtcga
    14341 cagctcgctg cccacggccg tcctggagat cttccaccgc ggactcgacc gggggcacgc
    14401 gggcgacagc ttcaccagcc tgatcgggac gttcaggaag cctgtggcgt aaggaaacgc
    14461 gtacgcggat gcggccgtga cacctcgggg gatgtcacgg ccgcacccgt gtgtgcggac
    14521 ctgtccggga aggcgtagcg gtgtgccgta tttcgtcgtt gtacgggaag tggccggatt
    14581 acgcgtagcc gaccgcgctg gagcagcttg cactggacgt actggatgta gaggacattc
    14641 gtccgaacgc ctggaaggtt ggccatgacc gactccggaa tccgtaccct cccgcccgcc
    14701 gcgcccgtgt tcccccagga ccgcacctgt ccgtaccggc cgcccgcgga ctacgaccgg
    14761 ctgatcgcgg acgggccgct gacgcgcgcc acgctgtacg acgggcgcca ggtgtggctg
    14821 gtgaccgggc acgccgaggc cagggccctg ctcgtcgatc cccggctgtc caccgaccgg
    14881 cagaatccgg ccttccccgt catcgccccg agcagcgagc ggcagggcga gatccgcctg
    14941 ccggtcctcg gcgtcgacga ccccgagcac ggccggcagc gccgcatgct catcccccac
    15001 ttcggcctga agcgcgtcac cgccatgcgg ccgcggatcc agcaggtcgt cgacggcctg
    15061 ctcgacacca tgctggccga ggggccgggg gcggatctcg tccgcgcctt cgccctgccc
    15121 gtgccgtcga tggtcatctg cgacctgctc ggcatcccct acgccgacca cgccttcttc
    15181 gaggacagtt cgcgggcgat gctcatcgcc gggacgtcgg acgagtcgat ggccgccttc
    15241 gacgagctgc gggactatct ggaggacctg gtcgaccgca ggcgggcgga gcccggcgag
    15301 ggcctcctcg acgaactcgt ggccgaccgg ctcgccgccg gggagctcga ccggaacgaa
    15361 gtcgcgctga ccgccctgct gttgctcgtc gccgggcacg agaccacctc gaacatgatc
    15421 tccctgggaa cgtactccct gctcgaacac cccgaccagc tcgccgcgtt gcgcgccgac
    15481 ccggcgctga tgcccggggc ggtcgaggag ctgctgcggt tcctgtccat cgccgacggg
    15541 ctcatacgcg tggccaccga ggacttcgag atcggcggcc ggaccgtacg cgccggggac
    15601 ggcgtcatga tcggcacctc gctggtcaac cgggacgcgg ccgcctacgc cgacccggac
    15661 gccctcgacg tccaccggtc ggcccgccac cacgtcgcct tcggcttcgg cgtccatcag
    15721 tgcctcggcc agaacctggc ccgggccgag atggagatcg ccctcaccac gctcttccag
    15781 cgcatcccga ccctgagccc ggccgtcgcc cccgacgagg tccccctcaa gcccgggcac
    15841 agcctgcagg gtctcttcgc cttccccgtc acctggtgac ggcctcacgg aaacggaaaa
    15901 ccaccatgag caccatccgt atctccatcg actccgacct ctgcgtcggc tcgggccagt
    15961 gcgcgctgac cgcgcccggt gtcttcaccc aggacgacga cggctacggc gcggtgctgc
    16021 ccggccgcga ggacggcggg ggcgacccgc tggcccgcga ggcggcgcgg gcgtgccccg
    16081 tcggcgcggt cacggtggag gaggactaga cctcccggcg ctagaggcgg tccgccttca
    16141 gggccatgtg cagcagcagg cggccctcgc cgtcgtccag gtccaggccc gtgagctgct
    16201 ccacccggga gagccggtag tagagcgtct gccggtggat gccgagcgcc gcggccgtcc
    16261 gccccgcctg ccccgcgcag tcgaggaaga cctccgccgt gcgggccagc tccgtgtggg
    16321 ccggtgccag cagcggccgg atggacggat cggccgcggc ttccgcgggc agcgcggaca
    16381 gcacgcggta cgggccgatg cccgaccact ccgccaccgg ccccagccgc gcctccgccc
    16441 cggccgcccg cgccgccgcc agcgcctcgc gccaggcggc gggcagctcc gcgagccccc
    16501 ggcgcggggt gccgagcccg gccgtggccc gtacgggacg gccgggcgca ccgcccgcgc
    16561 ggggtgagcg cagcagccgg tccgccgccg tgtgcgcggg cgccggggac gtcgtcgccc
    16621 gcaggcggat cagcgcggcc agcgcggccg acccgtcggg cagggcgtcc ggcaccgcgc
    16681 acagcgccgc cacccccgac tgcccggcca gtgccgaccc cgccgccgtc ccttccgtat
    16741 cgcccgcctc gcccgtctcg ccgtcggcgt cgcccgccgc ccgccagggc gccaccgcga
    16801 ccaccgccag cggcccgtcg cccgccgggc ccagcgcctc gcgcagcgcg gcccgcgccg
    16861 cgtcccggcc cgcgggcctg ccggtcagca gctcccgcag cagctcgccc agctcggcgc
    16921 ccgcccgggc ctcggcggcc agcagcgccc cgatccgggc ggccgtctcc atcgcctgcg
    16981 cgagccgcgg gtccgcgaac ggcacggaga ggtccagccc cgccaggtgc tcgtcgtcca
    17041 gcagccacac atagcccagc accacacccc gatggcgtac gggcaggcag atgcggccct
    17101 tgaacacccc ggccgccgga tccggcggga tccgcagcgg cgcctgcgcc cgcgcgatgc
    17161 cgaacgcctc gaaccacgcc cggacggccg ccgtcgaccg ccgctggagg atcgaccggg
    17221 tccgcaccgg gtccatcgtc agctcgacgt cgtcgtcacc gtcgtgggcg ccgaaggcga
    17281 tcagcccgaa atcccggtcc tccagggtcg cgggcgcgcc gagcgcggcc gatatctcgt
    17341 ccacgagctg ctgatagtcg ccgcgcatcg ccccgccgcg ctccttccgg ccctggggcc
    17401 cctccactgg accccttatg gcccgaattc gccccccggt ttcatgtgcc gctcactatt
    17461 gtcatacacg tgtctgagat ccgggccacg gatgcgtgac agctgtcgat ggccgaggat
    17521 cgctgtgatc tctaggtttc acgatgagtt acttatgccg ttcccctccg tggggccggc
    17581 cgtcatcgtg gaggtgccca gtgctgggtc ctgtgctgct cgccgcgtcc cgcagcgacg
    17641 ccatccgccg tcttgtctcg gccgcgccgg gcaccaagca ggtcgtcgcc cgcttcatcg
    17701 ccggcgagac cctcgaccag gtcatcccga tcgtcaagga cgccgcggcc gagggcctcg
    17761 aggtcaccct cgacgtggtg ggcgaggaca tcaccacggt cgagcagtcg tacgcggcgc
    17821 gtgacgccta cctggagctg atcggccgcc tcgaggagct cggcctgggc gccagggccg
    17881 agatgtcggt caagctctcc atgttcggcc aggcgctgga gggcggccac gagctcgcgc
    17941 tcgccaacgt ccgcccggtc gtcgaggccg ccgccgccat cggcaccacg gtcacgctcg
    18001 acgccgagga ccacaccacc ctcgactcga tgttcgccat ccacgaggag ctgcggaggg
    18061 acttcccgca gaccggctgc gtcatccagg cgtacctctt ccgcaccgag gacgacgccc
    18121 gccgcctggc cgcggccggc agccgtgtgc gtatcgtgaa gggtgcgtac aaggagccgg
    18181 cctccgtcgc gtaccaggac aaggccgaga tcgacaaggc gttcgtccgc atcgtcaaga
    18241 tcctgatggc gggcgagggc taccccatga tcggttcgca cgacccgcgg ctgatcgcca
    18301 tctcgcagga gctggcccgg caggcggggc gcaaactgga cgaatacgag ttccagatgc
    18361 tgtacggcat ccgcagcgag gagcacgtcc ggctggccgc cgagggccac cggatgcggg
    18421 tctacacggc ctacggcacc gactggtacg gctacttcat gcgccgtctc gccgagaagc
    18481 ccgcgaacct gctgttcttc gcccgctcca tcctcaccaa gggctgagcc gcccgacccc
    18541 cctgacgagc cccgaaggag aaacggaaaa tcatggacgc cgttacccag gtccccgccc
    18601 cggtcaatga gccggtgcac agctacgccc ccggttcccc cgagcgcgcc cgcctcgagg
    18661 cgaagctcaa ggagctggcc gggaacccca tcgacctgcc gatgacgatc aacggcgaga
    18721 agcggatggg cggcggcgag ccgttcaagg tcgtacagcc gcacaaccac gccgccgtgc
    18781 tcggcacgtt caacaacgcc acgcggcagg acgcccagga cgccgtcgac acggccctcg
    18841 ccgccgcccc ggcctggcgc gcgatgtcct tcgacgaccg cgccgcgatc atcctgcgcg
    18901 ccgccgagct gctggccggc ccctggcgcg agacgctggc cgcctccacc atgctgggcc
    18961 agtcgaagac cgcccagcag gccgagatcg acaccccgtg cgagctcgtc gacttctggc
    19021 gcttcaacgt gcacttcgcg cgccagatac tcgccgagca gccggtcgcc aactccaccg
    19081 gcgtgtggaa ccgcagcgac caccggccgc tggagggctt cgtctacgcg atcacgccct
    19141 tcaacttcac cgccatcgcc ggcaacctgc cgaccgcccc ggccctgatg ggcaacgtgg
    19201 tcgtctggaa gccgtccccg acccagaccc actccgccgt gctgctgatg cagctcctgg
    19261 aggaggcggg cctgcccaag ggcgtcatca acctggtgac cggcgacggc atcgccgtct
    19321 ccgaggtggc cctgaaccac cccgagctgg ccggcatcca cttcaccggt tcgaccaaga
    19381 ccttccagta cctctggaag acggtcggca acaacatcga gaactaccgg tcctacccgc
    19441 gcctggtcgg cgagaccggc ggcaaggact tcgtcgtcgc ccacccgagc gccgaccgcg
    19501 ccatcctgaa gaccgcgctg acccgcggct ccttcgagtt ccagggccag aagtgctcgg
    19561 cctcctcccg tgcctacatc ccgcgctcca tctgggagga cggcttcaag gaggagttcg
    19621 cggccgaggt cgacggcatc accatgggtg acgtcaccga cctgtcgaac ttcatcggcg
    19681 ccgtcatcga cgaccgctcc ttcgccaaga acaaggccgc gatcgaccgc gccaaggccg
    19741 acccgagctg cacggtcgtc gccggtggca cgtacgacga ctccgtcggc tacttcgtcc
    19801 gcccgacggt catcgagtgc accgacccgg cgaacgaggt cttcacgacc gagtacttcg
    19861 gcccgatcct cgccgtgcac gtctacgagg acggcgactt cgacgcgatg ctggcgcaga
    19921 tggagtccgt ctcggcgtac gccctgaccg gcgcggtcat cgcgcaggac cgtgccgcgg
    19981 ccgccgacgc gatggagaag ctccgcttcg ccgcgggcaa cttctacatc aacgacaagt
    20041 cgacgggtgc cgtcgtcggc cagcagccgt tcggtggcgg ccgtgcgtcg ggcacgaacg
    20101 acaaggccgg tgccgcgtcg aacctgatgc gctggacgtc gacccgctcc atcaaggaga
    20161 ccctggtccc gccgaccgac taccgttacc cgcacatggg ctgacctgcc ctcttgttga
    20221 ccccttctgt tgacgcgccc ccgtcggccc cccagccggc gggggcggtg tcgttccccg
    20281 cgccctgctc gccgtctcag atagtaggaa gaccgagtaa ttgggcagac accgccgccg
    20341 ccctgtccta gcgtgtaagg agccgaaacc ttccgctcca tcgagcgaca gcggccccgg
    20401 ccggcgcgcc ccgcgcaggt gacccctgcg gcaccccgcc ccgcgccctc ctcccggctc
    20461 cgtccgaccc ctctcggggg atcagccaag acgactcagt aagaggagac gtgacgtcca
    20521 tgcccgaaac cgccgtccgc aggatccgcc gcgccccccg tccggccgag agcgccgacc
    20581 gcaggaccga ccggatgaac gccgccgccg ccctccagcg cgcgctggac cgcagggaca
    20641 acggcggcga gaccggtcac tgacccggac gggtcacatc gaagtggtcg atgcgcgcgc
    20701 cgctctccgc cagcgccgtc acccgcagcc gcggccgcgg gccgggctcg gactcgaccg
    20761 cgaggaacga gtagccggtg taacgcacgc gggaccactc caccgtctcc ttgtgctcct
    20821 tgccgccctt ctcccagtgg taggtggcca cgctctccag gtccttgacg tggccctcgt
    20881 agctgtccgg caccgggaag tcgtacagcg acctccccgc cccgcccgcg gtgacgtaga
    20941 cgatgccgtc gcgggtggag tcggtgctcc cgccgatggg gagcttcttg ccgaccccgg
    21001 tgccccggat cgcgtcggtc cgctcgtaga cgtggttgtg gccgttgatg acgaggtcga
    21061 ccttgtgctt ctcg
//
