LOCUS       NZ_CP031455            22255 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces olivoreticuli subsp. olivoreticuli strain ATCC 31159
            chromosome, complete genome.
ACCESSION   NZ_CP031455
VERSION     NZ_CP031455.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivoreticuli subsp. olivoreticuli
  ORGANISM  Streptomyces olivoreticuli subsp. olivoreticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Complete genome sequence of Streptomyces olivoreticuli ATCC 31159,
            producer of anticancer bestatin and diverse secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2018) Tianjin Key Laboratory of Food
            Biotechnology, College of Biotechnology and Food Science, Tianjin
            University of Commerce, NO.409 Guangrong Road, Tianjin, Tianjin
            300134, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-JUN-2018
            Assembly Method                   :: SMRT Link v. 5.1.0
            Assembly Name                     :: TJCU_BT_311
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: SMRT Link v5.1.0
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003391135.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 04:49:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,459
            Genes (coding)                    :: 7,276
            CDSs (with protein)               :: 7,276
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 183
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 183
            Pseudo Genes (frameshifted)       :: 61 of 183
            Pseudo Genes (incomplete)         :: 150 of 183
            Pseudo Genes (internal stop)      :: 18 of 183
            Pseudo Genes (multiple problems)  :: 41 of 183
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:12:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5918674
            Orig. end                         :: 5940929
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031455.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Hongyu Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22255
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="31"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22255
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22255
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12255](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12255
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    562..577
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            799..2403
                     /locus_tag="DXZ73_RS26275"
     CDS             799..2403
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0031419 - cobalamin binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674553.1"
                     /locus_tag="DXZ73_RS26275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methylmalonyl-CoA mutase family protein"
                     /protein_id="WP_116213514.1"
                     /transl_table=11
                     /translation="MAREPDSSSTRSTESGLTVEPVYGPGALVGWDPAERLGAPGAYPF
                     TRGVYPTMYTGRPWTMRQYAGFGTAAESNARYRQLIAHGTMGLSVAFDLPTQMGHDSDT
                     PLASGEVGKVGVAIDSVEDMRVLFDGIPLGEVSTSMTINAPAAPLLLLYELVAEEQGVP
                     ADRLTGTVQNDILKEYIARGTYIFPPQPSLRLVADMFRYCGEVMPRWNTISISGYHMAE
                     AGASPAQEIAFTLADGIEYVRTAVAAGMDVDAFAPRLSFFFVARTTFLEEVAKFRAARR
                     IWARVMREEFGARDPKSLMLRFHTQTAGVQLTAQQPELNLVRVAVQGLAAVLGGTQSLH
                     TNAFDEAIALPTDKSARLALRTQQVLAHETDVTATVDPFAGSYAVESLTDAVEEAVLGL
                     MARVADRGGAVAAIEEGFQKAEIERNAYRIAQETDSGERVVVGVNRYRLDEEEPYEPLR
                     VDPAIEEQQVERLRRLRAARDAAAVEAALARLKKAAGGTDNVLPPMKTALRERATVGEV
                     CGALREVWGTYAPRESF"
     gene            2448..2660
                     /locus_tag="DXZ73_RS26280"
     CDS             2448..2660
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541718.1"
                     /locus_tag="DXZ73_RS26280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_116213515.1"
                     /transl_table=11
                     /translation="MSSPRRTCPVCSREIAVVGGRFARHDPPGRRASYDLISCPGSRRS
                     APLLSTEPRLFDPEEPDMKGQGQLF"
     gene            complement(2734..3075)
                     /locus_tag="DXZ73_RS26285"
     CDS             complement(2734..3075)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS26285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116213516.1"
                     /transl_table=11
                     /translation="MNPTPSPLPCPPRPAPEPDELWWLAPAICTPLALLLAYADFAGSG
                     FPLVWALGYALPLAFVAGAWGGAKVRYKRVQRIVLGITGCAFAFVYTKAVIAAFMPIAI
                     VLWLIHGDG"
     gene            3187..3432
                     /locus_tag="DXZ73_RS38840"
     CDS             3187..3432
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS38840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_205519407.1"
                     /transl_table=11
                     /translation="MCRRLSGRTGFPGRVVLAEDHFLLRDGLIRLLGAFGHEIVAAVDN
                     GSDLLTSLTGLRPKPGLHPDEGDNRRVLAVLAYLER"
     gene            3523..4782
                     /locus_tag="DXZ73_RS40130"
     CDS             3523..4782
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS40130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_116213517.1"
                     /transl_table=11
                     /translation="MRIPDRAAARHCLAVLGAAVAFAASAVPASATADDHGLRRGQLVS
                     AELVARIPQSTAAQQVHDRGYADDAAVPRYGVDHYRVLYRTIDPQGRPTTASGLVSLPE
                     NDRRELRVVVYEHGTFAARGDAPSGDPRVPAAPSVRADSVLFAGAGYATVAPDYLGLGS
                     GPGLHPYDDLASETTASVDLLRAARTVAHGQGRRLARGVQVTGFSQGGPAAMALGRALQ
                     RGAAPHFGLASLAPVSGPYDAQHAEAPAGLERGTLRGKDTNYLFAYWLIAMNRKYHLYD
                     DPSEVFRAPYAASVESLYDGTHGDAEIFTALPDTPRQLLTPKVIAWALHPTGNLLRAYE
                     ENDTSCTDWRPRVPVHLFAAHGDKDVAYENSLLCERALTAAGARVTLTDVGDVEYSPSR
                     RAALPRVLAWFEERFPADGR"
     gene            4855..5460
                     /locus_tag="DXZ73_RS26300"
     CDS             4855..5460
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104217.1"
                     /locus_tag="DXZ73_RS26300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Uma2 family endonuclease"
                     /protein_id="WP_240351497.1"
                     /transl_table=11
                     /translation="MADVVDPQTYARMRKIADELWPIVERLPGAWAVEIGAAGVVVMMS
                     PVKRHEAIATRIVRQINAQLVTTHPGQDVVAQSGAEVEHPVVGRMRRPDAVVVPLAVLD
                     EPGATVDPADLLAVVEVVSEPNPDNDYVEKAADYPAMGIPLYLLVDPRKGLVHTYADPA
                     PGSNGPHYATVLPYVFGDQVPFGPWNIDTTDFKRYADA"
     gene            complement(5491..5802)
                     /locus_tag="DXZ73_RS26305"
     CDS             complement(5491..5802)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS26305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116213519.1"
                     /transl_table=11
                     /translation="MPSEQTEPMRPVFTCVVCGCVYMPPKTMTYPHLGLTASPLHCGEA
                     PCRQVVARLPRQLQGLYAKAAWSRAKAWMAKEPTAAPAHARRRARAATRPQGGRSKLR"
     gene            complement(5824..5991)
                     /locus_tag="DXZ73_RS38365"
     CDS             complement(5824..5991)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS38365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162890337.1"
                     /transl_table=11
                     /translation="MPAPQEQTCTACNGEGITTKVEYTVETDAHGHQNPVTHTSYSSCT
                     LCGGTGSTSG"
     gene            6208..6543
                     /locus_tag="DXZ73_RS38370"
     CDS             6208..6543
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS38370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162890338.1"
                     /transl_table=11
                     /translation="MADVVDPQTYARMRKIADELWPIIERMPGAWAVEIGAAGVVVMMS
                     PVKRHEAIATRIVRQINAQLVTTHPGQDVVAQSGAEVEPPAVGRMRRPVPPPVTDGGGN
                     PRTAQPR"
     gene            complement(6500..6889)
                     /locus_tag="DXZ73_RS26310"
     CDS             complement(6500..6889)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS26310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116213520.1"
                     /transl_table=11
                     /translation="MEWARREDERWAAAFKLHLVTTYDPPKGLAQQALSEIHETVTEAD
                     RPAEALFGDPRQYAAQLAGPHRARQARRRKTYAAVAFALTITVASTDALRGLCMTSFWF
                     WIGLLAVVFSVVNAVVLYGDFRRHR"
     gene            complement(7001..7450)
                     /locus_tag="DXZ73_RS26315"
     CDS             complement(7001..7450)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040372.3"
                     /locus_tag="DXZ73_RS26315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6294 family protein"
                     /protein_id="WP_116213521.1"
                     /transl_table=11
                     /translation="MKSPRRAIRTLLAAAVLVTAFAAPAAAVPADTDPAASGTVRQGIA
                     TDYKWWTWGDLSAGDCHQTGGELRLYSDGKLTFTAKTQTTFTLSGDIWHARFGLKNTSG
                     QELYRTTTYDSPTMWPSKWYDMNAQGTFEPSVYAATAQVTQYYSC"
     gene            complement(7501..7842)
                     /locus_tag="DXZ73_RS26320"
     CDS             complement(7501..7842)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS26320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116213522.1"
                     /transl_table=11
                     /translation="MRALRKIGRIGLTIGAAAALVTGLTANAQAADGPFSYIRADTGAP
                     DELDNPPNDVCLPIPGGAAHAENDTDATAFVYSDGSCRRLLAIVGVGGTWDETGPPPEP
                     AHSVGFGSG"
     gene            complement(7907..8122)
                     /locus_tag="DXZ73_RS26325"
     CDS             complement(7907..8122)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.4"
                     /locus_tag="DXZ73_RS26325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_116213523.1"
                     /transl_table=11
                     /translation="MSRFIKSSYSSVVENCVEISLSPDLISIRDSKNPNGPALHFTSLA
                     YRLFIHALMNCELCSPIRVAARQHSS"
     gene            complement(8119..8994)
                     /locus_tag="DXZ73_RS26330"
     CDS             complement(8119..8994)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.3"
                     /locus_tag="DXZ73_RS26330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_162890339.1"
                     /transl_table=11
                     /translation="MSDAKPTMLRRRLGAILKTMRVRTGLNLAEAAKLLGLAGPPALSK
                     IENGKQRPDLEKFFTVYGVKDAVRIAETMEIARLSDSARQRRIFTQFKDVIRPQFADFL
                     ELEEIATHTDTYAALAIPGLLQTAAYANAIIQGGSVWSTARDVRDFVELRMKRQDVLAL
                     TPGDEASRTPLALRCVLDEACLRRAVGGPDTLQGQLEHLLLMSKLPNIELRVLPFTTGA
                     HTGMDGSFTIFHLAAGEPVVAVEPLTHSLYLDEDARVARYTHAFEYLLDQALAPAASRD
                     FITRIAKETT"
     misc_feature    complement(8620..8622)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            9171..9515
                     /locus_tag="DXZ73_RS26335"
     CDS             9171..9515
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS26335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116213525.1"
                     /transl_table=11
                     /translation="MTYRNGAFVVDTREGWIGQVIDSAGSRVHVRAPGGGAEWEVPFSV
                     LRLATREERDEVGLWPRGTRSRKGCPECPALELAWRDAAEGGDKLKEATALVALRRHGR
                     VVHMLPGGRA"
     gene            9512..9748
                     /locus_tag="DXZ73_RS38375"
     CDS             9512..9748
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040038.3"
                     /locus_tag="DXZ73_RS38375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6255 family natural product biosynthesis
                     protein"
                     /protein_id="WP_162890340.1"
                     /transl_table=11
                     /translation="MSTAVATCAHRAGWVRGKGEARCGSCGVVRFTEYGALRPPGLAEA
                     VKPPHGGSADRAAALWVMRRTRRRTEWWGRAVN"
     misc_feature    9814..9831
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.16"
                     /tool="antismash"
     gene            9859..9993
                     /locus_tag="DXZ73_RS26340"
     CDS             9859..9993
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020123200.1"
                     /locus_tag="DXZ73_RS26340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_116213526.1"
                     /transl_table=11
                     /translation="MEQQEEVYEPPELMEVGDFAELTLGTGNGTYFEGGYAPWYVRPS"
     CDS_motif       9859..9930
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MEQQEEVYEPPELMEVGDFAELTL"
                     /locus_tag="DXZ73_RS26340_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9931..9993
                     /prepeptide="core"
                     /locus_tag="DXZ73_RS26340_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="6.40"
                     /molecular_weight="2161.3"
                     /monoisotopic_mass="2160.0"
                     /core_sequence="GTGNGTYFEGGYAPWYVRPS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MEQQEEVYEPPELMEVGDFAELTL"
                     /leader_location="[9858:9930](+)"
     gene            10001..11842
                     /locus_tag="DXZ73_RS26345"
     CDS             10001..11842
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="DXZ73_RS26345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_116213527.1"
                     /sec_met_domain="Asn_synthase (E-value: 3.2e-41, bitscore:
                     140.9, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSEAWFAVLPDGESGGTAARALRRGTTEVIDHHSGRPWLVGSWP
                     AGQVVVAAVGGARLAVIGRCPVTTDALASRLRRVRDVADVEGALAGLEGSFHAVASVGG
                     RVRVRGSASAVRRVFRARVDGVTVAASRADVLARAVGAGVDERRVALHLLSSPPPYPLD
                     AGPGLWRGVEALPAGSFLLLEADGRAEVHRWWNPPEPQLSLAEGAVEVGRALTAAVDSC
                     TADAKTVSSDLSGGMDSTSLCFLAARGQARLVTFRWESVDAANDDAAWAGLAAARLPGS
                     AEHVVPERSRAPLWFSGLADLEAAADEPGSWVRDGARLATLVGLMTEHGSQLHLSGGGG
                     DELFCAFPSYVHDSLRSHPLPTLGLVRRQRLLQRWSLWPLLRGLADRSTFSQWLAAWAD
                     GLTGTRRPSPARTSTAWGADLRMPPWASPDAVRSVQSLLRAAAADLPEPLAAQRGQHAA
                     LSCVQMCGRGFRQVDQVTSAQGLPYAAPYLDDRVIEAALSVRVAERSARDRYKPVLATA
                     MSGIVPDTVLARSTKGEYSADFHLGLRRNKAALAEIVAESRLARAGLLDAAALRASLRR
                     PELSPDLMRSLDNTLACEMWLRSALGAGGPGPEAVVG"
     gene            11839..12255
                     /locus_tag="DXZ73_RS26350"
     CDS             11839..12255
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175265.1"
                     /locus_tag="DXZ73_RS26350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_116213528.1"
                     /sec_met_domain="PF13471 (E-value: 5.5e-25, bitscore: 86.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIHQVPYSRGFFARAGRPAAFMAAATARLLVLLPPRRIRRILSF
                     LRRGAAPATMAQALAARQAVVATSARCAGEGCLQRSVATALLCRLRGVWPDWCTGVRTA
                     PFRAHAWVEAEGEPVGEPFPAGYYRPLMRVAAGR"
     gene            12445..13392
                     /locus_tag="DXZ73_RS26360"
     CDS             12445..13392
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS26360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162890341.1"
                     /transl_table=11
                     /translation="MGSRPARRFWSLVLAAAVGLIFSSQFTASATVAAPRSVGGSPLYT
                     AHDASGRVTVTVFKNVSSDYREIWDNQEVTVGDDAMVAIGGGATAVEYPAGALLTASYP
                     NDSRTGWIVSAKDHAIAQSYQLTTYVIGLKIAGMTRDELKNYLVYNSDGQAYGSTPSAS
                     SHLNSDTDVLLGGGFRTYWNGWGQLATGSYPSGPVEWTAGSKDHLHASPGTIQTWAIGI
                     KRNLPVGWIDTYPSYPVPSGVSNHPSASARVQPGYVMTGGGGQVKCAGWGCALWSLEPS
                     IDNSGYQSFTARAKDHAEAATGTTWAWTIGIRLV"
     misc_feature    13395..13410
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            13496..14110
                     /locus_tag="DXZ73_RS26365"
     CDS             13496..14110
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015696.4"
                     /locus_tag="DXZ73_RS26365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ALF repeat-containing protein"
                     /protein_id="WP_116213531.1"
                     /transl_table=11
                     /translation="MKLARVSAVVVAAAIAPAVLLSSPSFAAGGAAKSPAAVSTAKQGE
                     TTKVSDMSDDDLRVAVLTIMGKGGRAVKDAGNAAMNGTVADLRHFLEVGQFRAREEDDR
                     VEALTIMGKGGRAVKDAGSQALDGTPADVRRFIEVGQFRAREEDDRVEALTIMAKGGKA
                     VKAAGDKALKGTAADVRHFIEVGQYEARKLDEQKKPTAKKR"
     gene            complement(14130..14810)
                     /locus_tag="DXZ73_RS26370"
     CDS             complement(14130..14810)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014626749.1"
                     /locus_tag="DXZ73_RS26370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="rhomboid-like protein"
                     /protein_id="WP_240351498.1"
                     /transl_table=11
                     /translation="MVGNNMVRAVRRLPATTAYVALLVTTAAWMSSQSLREQARFVRHN
                     SSNVHHLEVGKWWTLFTSGLVVDGVPVLLGIAAVAAVLGLAEWRWGSLRGFGVFLLGHL
                     VATLLTEGAMWLMHLAHLPGVLARARDVGISYGLVATAACLLALGGHRARRYGLPALTA
                     ALTVAWIVNHELADAGHLVALGLGVLGARTRWLRTPRRAPREAPQEALQARAATEAPPV
                     AAVR"
     gene            complement(14868..15383)
                     /locus_tag="DXZ73_RS26375"
     CDS             complement(14868..15383)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014150661.1"
                     /locus_tag="DXZ73_RS26375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_116213532.1"
                     /transl_table=11
                     /translation="MSRTTATAATAARVRVFAMMDADGDRVVTRHDYLSRIDRTVLATE
                     RMEDDPLVVAARAAGLKAWDEMDADGDGKLTFDEYNAWVGADKFDNICRFALGALFDLV
                     DADGDGALDKAEFTTLRTALNNPPGNAAAAFDALDADGDGRVGRAAYLASIRAYIVGDS
                     SPMGEALY"
     gene            15636..16145
                     /locus_tag="DXZ73_RS26380"
     CDS             15636..16145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS26380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162890342.1"
                     /transl_table=11
                     /translation="MMLGSLALVVSSLVWAPAGRAGTGEYEAVTCVGNAHGRYDPPLTL
                     RPQETRIHADVRYTCTTAPGHTVPATGSFDAVAPTASCLSLSGAGGTETIRYEGGGRSV
                     IVIDGVTARAVGLLDAQQSGRVTEGRGEGHFVRRTVTSTPRQSPTDCLASGLQGTWSAV
                     QLEILP"
     gene            16250..16855
                     /locus_tag="DXZ73_RS26385"
     CDS             16250..16855
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574977.1"
                     /locus_tag="DXZ73_RS26385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="disulfide bond formation protein DsbA"
                     /protein_id="WP_116215865.1"
                     /transl_table=11
                     /translation="MTHKADFYFDPICPFAWITSRWILEVERHRDLDLRFRVMSLSVLN
                     EGRADLPERYQRLFDVGWGPVRVCIAAAREHGEHVLRDLYTALGTRIHDADREVSDALI
                     REALAEAGLPEALADAAHTTEYDEELRKSHHEGMDPVGEDVGTPTLHVDGVAFFGPVLN
                     AIPRGEEAARIFDGVRLLAGNPHFFELKRTRTGGLDFS"
     gene            complement(16912..18411)
                     /locus_tag="DXZ73_RS26390"
     CDS             complement(16912..18411)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (85-468). E-value:
                     1.5e-18. Score: 59.3. Matches aSDomain:
                     nrpspksdomains_DXZ73_RS26390_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007447970.1"
                     /locus_tag="DXZ73_RS26390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_116213534.1"
                     /sec_met_domain="PF00561 (E-value: 6e-24, bitscore: 83.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPLTRKALLTTLSAAACAATLTAPTHAATPTAKAPRLTWQPCAE
                     KDGRECAVLPMPLDYSRPGGPTVDIAVSRLRSDHPEARRGTLLLIPGGPGGSGREEVAR
                     RGAQLRKETGGAYDIVGLDPRGVGGSTQADCGISDDDRRPVNLRPWPGPDGDISANVAR
                     ARRVADACARNGGALVRSLSTANEVRDLDRFRQALGEEKLSALGVSYGTYVGAVYAQKF
                     PQHTDRWVLDSSGDPDPERVERGWLANMSGAADDRFPDFAEWAADPARGDQRLAAKAAD
                     VRPMFLALAAGLDREPREFADTGHELTGNLLRQVMQNSLYSDADFPRLADLIRAARTGT
                     GPLTVADPAPQPLSQSDAAVFAGVVCNDVGTWPRSIPSYARAVATDRARHPLTAGMPAG
                     ILPCAFWKTPSADKPTRITPNGPSNVLMIQNLRDPSTPYRGALKMRAAFGERARMVTVD
                     AGGHGVYLDNGNACGDRAVTKFLVRGERPGADAFCSAEPRH"
     aSDomain        complement(17008..18156)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXZ73_RS26390_Abhydrolase_1.1"
                     /evalue="1.50E-18"
                     /label="DXZ73_RS26390_Abhydrolase_1.1"
                     /locus_tag="DXZ73_RS26390"
                     /protein_end="468"
                     /protein_start="85"
                     /score="59.3"
                     /tool="antismash"
                     /translation="TLLLIPGGPGGSGREEVARRGAQLRKETGGAYDIVGLDPRGVGGS
                     TQADCGISDDDRRPVNLRPWPGPDGDISANVARARRVADACARNGGALVRSLSTANEVR
                     DLDRFRQALGEEKLSALGVSYGTYVGAVYAQKFPQHTDRWVLDSSGDPDPERVERGWLA
                     NMSGAADDRFPDFAEWAADPARGDQRLAAKAADVRPMFLALAAGLDREPREFADTGHEL
                     TGNLLRQVMQNSLYSDADFPRLADLIRAARTGTGPLTVADPAPQPLSQSDAAVFAGVVC
                     NDVGTWPRSIPSYARAVATDRARHPLTAGMPAGILPCAFWKTPSADKPTRITPNGPSNV
                     LMIQNLRDPSTPYRGALKMRAAFGERARMVTVDAGGHGVYLDN"
     gene            complement(18491..19918)
                     /locus_tag="DXZ73_RS26395"
     CDS             complement(18491..19918)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019545467.1"
                     /locus_tag="DXZ73_RS26395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amidase"
                     /protein_id="WP_116213535.1"
                     /transl_table=11
                     /translation="MDRTAAGLGEQARALAAGDVTSRTLVEEALRRIEETQPVLNAFRR
                     VRAEAALAEADAADRRLAAGHRAPLLGVPLAVKDDMDVAGEPTAFGCAGDFPPRPADSE
                     AVRRLRAAGAVIVGKTNTPELGQFPVTEGPAFGATRNPWSHEHTPGGSSGGAAAAVAAG
                     LVPAALGSDGAGSLRIPAAWSHLVGIKPQRGRVSTWPEPESFHGITCHGPLARTVADAA
                     LLLHVVSGSHRGDLHRPPAVDLLAAAGREPRRLRIALSFRPAYAVARQWLDPAVRSATL
                     RIAERLAALGHEVVEAEPRYGPIGLTFVPRSMAGIRDWAERAPDRTLLDPRTNANARNG
                     RLLGGPLLRAARAAEGPLRRRVGELFGRFDVLLTPTTAVPPLRIGALDGLSTRHTDEAM
                     IGACPYAWPWNVLGWPGISVPAGLTDEGLPMGAQLLGPESSEPLLISLAAQLEADQRWF
                     ERWPAGTAPGLREAGQA"
     gene            complement(20009..20710)
                     /locus_tag="DXZ73_RS26400"
     CDS             complement(20009..20710)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187771.1"
                     /locus_tag="DXZ73_RS26400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FCD domain-containing protein"
                     /protein_id="WP_116213536.1"
                     /transl_table=11
                     /translation="MENQGQGLHARVLESLGPAITAGEYAPGTVLRTDELEERFAVSRT
                     VVREAVRVLESMRLVTSRRRVGVTVLPTEEWNVYDPRVIRWRLAGADRPRQLRSLTVLR
                     SAVEPVAAGLAARLATPAQCAELTEHALGMVATSRGQQLAGYLVHDIAFHRVILRASGN
                     EMFARLGDVVAEVLTGRTQHEVMFTDPDPAAVTLHVRVAEAVREHDSVRAEALTREITA
                     GAMAELDILAP"
     gene            20862..21374
                     /locus_tag="DXZ73_RS26405"
     CDS             20862..21374
                     /EC_number="2.7.1.12"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046316 - gluconokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0046177 - D-gluconate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988030.1"
                     /locus_tag="DXZ73_RS26405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gluconokinase"
                     /protein_id="WP_116213537.1"
                     /transl_table=11
                     /translation="MQAPHAPHVVAVMGVSGTGKTTIGPLVADALGVPYAEGDDFHPPA
                     NIAKMSSGTPLDDADRAPWLDAVGAWAHSRAGLGGVVSCSALKRAYRDRLRAAAPGIVF
                     LHLTGDRALIAERMAARKGHFMTGRLLDSQFATLEPLEADEAGVAVDVAPGPEAVAERA
                     TAALRKL"
     misc_feature    complement(21662..21677)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
ORIGIN
        1 acgcccggtc cctcgccctc gcccggcaag gacggcaact cccgcccgag cggcagcccg
       61 tacacccccg caccgaaggg cggcggtgcc accaccgggc acggcggcaa ggaggacgga
      121 cccgggggcg gcccctcggc gaccccccgc cgcgacggcg gtggccacgg cgacgacgac
      181 ggggacacgg ccaagcgcgg ctccgactgg gccgcccgca tgtgccgtga cttcctcgcc
      241 gcgcagcagc accccggcca gggtgtcgac gagcacgacc tccgcgactt ggaacacgtc
      301 gtgggcgcgg cgggcgcgga cgccctgcgc gcgtactgcg agcgccatgc gtcggacggc
      361 ggcagcaaga gcgccccggg caagggcggc gacgacggca aggccaaggg cggtgacgac
      421 ggcgacggcg gccaccgcgg ccggcccacc gggctgttgc cgcccgtcct cggcggcccc
      481 ggcctccagc tcccgaaggt gcttccggtc ccgctcaccc ccttggtgtg acgttttccg
      541 tgccgccggc gctgtaagaa gtgtgccgac tggtcatcgg ccgcgtacga gccggagttc
      601 cccccatacc gtcggctcgg cgcaccggcg cgggcggggc tcttcccccg gctctgcccg
      661 cgcccccctc agccgtcacc tctcagccgt cgcgccggtg cttcccttcg ccacccggcg
      721 gagcatcctg tacgtacgga agacgtaccg aaggacgaca ccgcacggcg tgacgagcag
      781 cagcgggagg cggcacccat ggcgcgcgag ccggacagca gcagcacgcg gtcgaccgag
      841 tccgggctga ccgtcgaacc cgtctacgga cccggggcgc tcgtcggctg ggatcccgcc
      901 gagcggctcg gcgcccccgg cgcgtacccc ttcacccgcg gcgtctaccc gacgatgtac
      961 accggccgcc cctggaccat gcggcagtac gcgggcttcg gcaccgccgc cgagtccaac
     1021 gcgcgctacc ggcagctcat cgcgcacggc accatgggcc tctcggtcgc cttcgacctg
     1081 cccacccaga tgggccacga ctcggacacg ccactggcga gcggcgaggt cggcaaggtc
     1141 ggcgtcgcga tcgattccgt cgaggacatg cgggtgctct tcgacggcat cccgctcggc
     1201 gaggtctcca cgtcgatgac catcaacgcg cccgccgcgc cgctcctgct gctgtacgag
     1261 ctggtcgccg aggagcaggg cgtgccggcc gaccgcctca ccggcacggt gcagaacgac
     1321 atcctcaagg agtacatcgc ccgcggcacg tacatcttcc cgccgcagcc gtcgctgcgg
     1381 ctcgtcgcgg acatgttccg gtactgcggt gaggtgatgc cgcggtggaa cacgatctcg
     1441 atctccggct accacatggc cgaggcgggt gcctcgcccg cgcaggagat cgcgttcacc
     1501 ctggccgacg gcatcgagta cgtgcgcacc gccgtcgccg ccggcatgga cgtcgacgcc
     1561 ttcgcgcccc ggctgtcgtt cttcttcgtc gcgcggacca cgttcctgga ggaggtcgcg
     1621 aagttccgcg cggcgcggcg gatctgggcg cgggtgatgc gcgaggagtt cggcgcgcgc
     1681 gaccccaagt cgctgatgct gcgcttccac acgcagacgg cgggtgtgca gctgaccgcg
     1741 cagcagccgg agctcaatct cgtacgggtc gcagtgcagg gcctggcggc ggtgctcggc
     1801 ggcacccagt cgctgcacac caacgccttc gacgaggcca tcgccctgcc caccgacaag
     1861 tcggcccggc tggccctgcg cacgcagcag gtgctggccc acgagacgga cgtgacggcc
     1921 acggtcgacc ccttcgccgg gtcgtacgcg gtggagtcgc tgaccgacgc cgtcgaggag
     1981 gcggtgctcg gcctcatggc ccgggtggcg gaccgcggcg gggcggtcgc cgccatcgag
     2041 gagggcttcc agaaggccga gatcgaacgc aacgcgtacc gcatcgccca ggagaccgac
     2101 agcggcgagc gcgtcgtcgt cggcgtcaac cgctaccggc tggacgagga ggagccctac
     2161 gaaccgctcc gcgtcgaccc cgcgatcgag gagcagcagg tggagcgcct gcggcggctg
     2221 cgcgccgccc gcgacgcggc ggcggtggag gccgcgctgg cccgtctgaa gaaggcggcc
     2281 gggggaacgg acaacgtcct gccccccatg aagaccgcgc tcagggagcg ggcgacggtg
     2341 ggggaggtgt gcggggcgct gcgcgaggtg tggggcacct atgcgccgag ggagtcgttc
     2401 tgaccggacc ggggacccgc gcccgccggg tgagggaaaa tggcgggatg tcctctccgc
     2461 gccgcacgtg ccccgtctgc tcccgagaga tcgccgtggt cggcggtcgc ttcgcccgcc
     2521 acgacccccc gggccgccgc gcgtcctacg acctcatctc ctgccccggc tcccgccgct
     2581 cggcccccct cctctcgacg gaaccccgcc tcttcgaccc ggaggaaccg gacatgaagg
     2641 ggcaggggca gctgttctga ggccttcgca tagcctcgac cggatatcgg acggtcgatg
     2701 tgggggcggc gcgaacccac ggcctgagcg cgctcacccg tcgccgtgga tgagccacag
     2761 cacgatggct atcggcatga acgccgctat cacggccttg gtgtacacga acgcgaaagc
     2821 gcagcccgtg atgccgagga cgatgcgctg cacccgcttg taccgcacct tcgcgccgcc
     2881 ccacgcgccc gccacgaagg cgagcggcag cgcgtagccg agggcccaga cgagcgggaa
     2941 gccggagccc gcgaagtccg cgtacgcgag cagcagggcg aggggtgtgc agatcgcggg
     3001 cgccagccac cacagctcgt ccggctcggg cgcggggcgg ggtgggcagg gcagtgggga
     3061 cggcgtcggg ttcatgaacc cagtccaccg cggcgggtcg tcgtaccggc agcgcgcgcg
     3121 tactcattcg tacgtgcgct cgtactcagc gcagttcgga gcggctgtgg cccttgtacg
     3181 gtcgaggtgt gccgacgcct gagcggacgg acgggcttcc cgggccgcgt tgtcctcgca
     3241 gaagaccact tcctgctcag ggacggtctg atacggctgc tcggggcgtt cggccacgag
     3301 atcgtcgcgg ccgtcgacaa cggctccgac ctgctgacct ccctcaccgg actgcgtccg
     3361 aagccgggcc tgcacccgga cgagggcgac aaccggcggg tgctggcggt tctggcgtat
     3421 ctggagcggt gagagcgcgc ctccccgatc agggtgaact cggggtattc gcaggggagt
     3481 tcccggaggc gtggtgcgtg ccgcggtgcg cacgatgagc gcatgagaat ccccgatcgc
     3541 gccgccgcgc gccactgtct cgccgtgctc ggcgccgccg tggccttcgc cgcctcggcc
     3601 gtccccgctt cggccaccgc cgacgatcac ggcctgcggc gcggccagtt ggtctccgcg
     3661 gagctcgtcg ccagaatccc gcagtccacc gccgcccagc aggtgcacga ccgcggctac
     3721 gccgacgacg ccgcggtgcc gcgctacgga gtggaccact accgggtgct ctaccgcacg
     3781 atcgacccgc agggccgccc caccaccgcg agcggcctgg tcagcctgcc ggagaacgac
     3841 cggcgggagc tgcgcgtggt ggtctacgag cacggtacgt tcgccgcgcg gggcgacgcg
     3901 ccgtccggcg acccgcgcgt gccagcggct ccgtcggtgc gggccgactc ggtgctcttc
     3961 gcgggtgccg gctacgccac agtggccccc gactacctgg gcctgggcag cggcccgggc
     4021 ctccacccct acgacgacct ggcctccgag accaccgcct cggtcgacct gttgcgcgcc
     4081 gcccgcacgg tggcccacgg ccaagggcgc cgcctcgccc ggggcgtcca ggtcaccggg
     4141 ttctcacagg gcggtcccgc cgcgatggcc ctgggccggg ccctgcagcg cggcgccgcc
     4201 ccgcacttcg gcctggcgtc gctcgccccg gtcagcggcc cctacgacgc ccagcacgcc
     4261 gaggcaccgg cgggcctgga gcgcggcacg ctgcggggca aggacaccaa ctacctcttc
     4321 gcctattggc tcatcgccat gaaccgcaaa taccacctgt acgacgaccc gtccgaggtg
     4381 ttccgggcgc cgtacgcggc ctccgtcgaa tccctctacg acggcacgca cggcgacgcc
     4441 gagatcttca ccgccctccc cgacaccccg cggcaactcc tcaccccgaa ggtcatcgcc
     4501 tgggccctgc accccacggg caacctgctg cgcgcctacg aggagaacga caccagctgc
     4561 accgactggc gcccccgcgt ccccgtccac ctcttcgcgg cccacggcga caaggacgtg
     4621 gcctacgaga actccctgct ctgcgaacga gcactgaccg ccgccggtgc cagggtgaca
     4681 ctcacggacg tcggcgacgt ggagtattcg ccctcgcgtc gggcggcact tcccagggtg
     4741 ctcgcgtggt tcgaggagcg ctttccggcg gacggcaggt agggggcgcc gcgcgccgga
     4801 ccttgtacgg tcgaggtgtc cggcgtgatg ggcgccgagc gaccaggaga caacgtggcc
     4861 gatgtcgtag atccacaaac ctacgcgcgc atgcggaaga tcgccgacga gctctggccg
     4921 atcgtcgaac gcttgccagg cgcatgggca gttgagatcg gggcggcggg tgtcgtcgtc
     4981 atgatgagcc cggtcaagcg ccacgaggcc atcgccaccc gcatcgtgcg gcagatcaat
     5041 gcccagctcg tgaccacgca ccccggtcag gacgtcgtcg cccagtccgg tgccgaggtg
     5101 gagcacccgg tggttgggcg gatgcgccgc ccggacgccg tggtcgtccc gctcgctgtt
     5161 ctggacgagc cgggagcgac ggttgatccc gccgaccttc tcgccgtggt cgaggtggtg
     5221 tccgagccca acccggacaa cgactacgtc gagaaggccg ccgactaccc ggccatgggc
     5281 atcccgttgt acctgctggt cgaccctcgc aagggcctcg tccacaccta cgccgacccc
     5341 gcccccggct ccaacgggcc gcactacgcg acggtgttgc cctacgtctt cggcgaccag
     5401 gtgcctttcg gcccgtggaa catcgatacg accgacttca agcgctacgc cgacgcctga
     5461 gcggacgggc ttccagggcc gcgctcgtac tcagcgcagt ttggagcggc cgccctgcgg
     5521 ccgggtggcc gcgcgggcgc ggcggcgtgc gtgtgcgggg gcggccgtgg gttccttggc
     5581 catccatgcc ttcgcccggg accaggcggc cttggcgtag aggccctgga gctgtcgggg
     5641 cagccgtgcg acgacctgtc ggcagggggc ttcgccgcag tggagagggg atgcggtcag
     5701 gcccaggtgc gggtaggtca tggtcttggg cggcatgtag acgcacccgc agaccacgca
     5761 ggtgaacaca ggacgcatcg gctcggtctg ctcggatggc acgagaacct cttccctgta
     5821 cggctagccc gacgtgctgc ccgtgccgcc gcagagagtg caggacgaat agctggtgtg
     5881 ggtaacggga ttctggtgcc cgtgggcatc ggtctcgacg gtgtactcga ccttggtggt
     5941 gatgccctcg ccgttgcagg ccgtgcacgt ctgctcctgc ggtgcgggca tcggcggctc
     6001 ccctcgacac cccgaggata gcgagcggcc acctcctgcc gcagcccgct gtatctccct
     6061 gaagctgggc gtgcacccga acgagggcgg caaccggcgg gtgccggcgg ttctggcgta
     6121 tctggaacgg tgagagcggg cggcgcgccg cgccttgtac ggtcgaggtg tccggcgtgg
     6181 tgggagctga gcgaccgggg aggcgccgtg gccgatgtcg tagatccaca aacctacgcg
     6241 cgcatgcgga agatcgccga cgagctctgg ccgatcatcg aacgcatgcc aggcgcatgg
     6301 gcagttgaga tcggggcggc gggtgtcgtc gtcatgatga gcccggtcaa gcgccacgag
     6361 gccatcgcca cccgcatcgt gcggcagatc aatgcccagc tcgtgaccac gcaccccggt
     6421 caggacgtcg tcgcccagtc cggtgccgag gtggagcccc cggcggtcgg gcggatgcgt
     6481 cgtcccgtgc cgccgcccgt caccgatggc ggcggaaatc cccgtacagc acaaccgcgt
     6541 tgaccaccga gaagaccacc gccagcaagc cgatccagaa ccagaacgag gtcatgcaca
     6601 ggccgcgtag ggcgtcggtg ctcgccacgg tgatggtcag tgcgaatgcc acggccgcgt
     6661 acgtctttcg acgccgcgcc tgtcgcgcgc ggtgtgggcc ggccagttgg gccgcgtact
     6721 gtcgcgggtc gccgaatagc gcctccgctg gtctgtcggc ctcggtcacc gtctcgtgga
     6781 tctcggacag cgcctgctgt gccagcccct tgggcgggtc gtacgtcgtg accaggtgga
     6841 gtttgaaggc ggctgcccac ctttcgtcct ccctgcgtgc ccactccact gtttcctcct
     6901 ccgccgggta gatcaaggga accgcatcgg ccggacgcac ggcaaacgcc gcactccgag
     6961 ccgctcgcgc ggcctggagc acggcgtggc ggccgggccg tcagcaggag tagtactgcg
     7021 tgacctgggc cgtggccgcg tacacgctgg gttcgaacgt gccctgtgcg ttcatgtcgt
     7081 accacttgct cggccacatc gtcgggctgt cgtaggtcgt ggtcctgtag agctcctggc
     7141 cgctcgtgtt cttcaggccg aagcgcgcgt gccagatgtc gccgctcagc gtgaaagtcg
     7201 tctgcgtctt tgcggtgaag gtgagtttgc cgtcggagta gagccgcagc tctccgccgg
     7261 tctggtggca gtcgcccgcg ctcaggtcgc cccaggtcca ccatttgtag tccgtggcga
     7321 tgccctgcct gaccgtgccc gaggctgcgg ggtccgtgtc ggccggaact gccgccgccg
     7381 gggcggcgaa tgccgtgacg aggacggccg cggccagcag agtcctgatg gcccgccggg
     7441 gggatttcat gggggttctc cgttcgggag gagggcagcc ccttcaattg ccgtgcgctc
     7501 ttatccggag ccgaatccca cggagtgggc cggctcgggc ggcgggcccg tctcgtccca
     7561 ggtgcccccg actcccacga tcgccagaag ccggcggcac gagccgtcgg agtagacgaa
     7621 agccgtggcg tccgtgtcgt tttcggcgtg ggccgcgccg ccggggatgg ggaggcacac
     7681 gtcgttcggc gggttgtcga gctcgtcggg ggctcccgtg tcggccctga tgtacgagaa
     7741 cggtccgtcg gcggcctggg cgttggcggt cagtcccgtc accagcgcgg cggccgcgcc
     7801 aatggtgagg ccgatcctgc cgatttttcg gagtgcgcgc atgaggacgc tctcccttcc
     7861 ctcttggcag gggatggaat gggagcgtcc caactttttg gggagtttag gaagagtgtt
     7921 gacgtgcggc cactcgaatg ggtgagcaga gttcgcagtt cataagagcg tgaataaata
     7981 ggcggtacgc gagtgaagtg aagtgcagtg cggggccgtt ggggttcttg gagtcgcgta
     8041 tggatatgag gtcgggggag agggatatct ccacgcagtt ctcgaccacg gagctgtagc
     8101 tgctctttat gaatcggctc atgtcgtttc cttggcgatc cgcgtgatga agtcccgtga
     8161 tgcggcgggg gccagtgcct ggtccagcag gtactcgaat gcatgggtgt atcgagcgac
     8221 ccgggcgtcc tcgtccaggt agagcgagtg cgtcagcggc tccacggcaa ccacgggctc
     8281 acctgcggcc aggtggaaga tcgtgaagct gccgtccatc ccagtgtgcg cgcctgtcgt
     8341 gaacgggaga acccgcagtt cgatgttcgg cagtttcgac atgaggagca ggtgctcaag
     8401 ctgcccttgc agggtgtcgg gcccgccgac cgcgcgcctc aagcatgcct cgtcgaggac
     8461 gcaccggagc gcgagcgggg ttctggaggc ttcgtcgccg ggtgtgagcg ccaggacgtc
     8521 ttggcgcttc atgcgcagct ccacgaagtc gcgcacgtca cgtgccgtgc tccatacgct
     8581 gcctccttgg atgatcgcgt tggcatacgc cgcggtctgt aacagaccgg ggatggcgag
     8641 cgccgcgtag gtatccgtgt gggtggcgat ttcctccaac tccaggaagt cggcgaactg
     8701 cgggcggatc acatctttga actgcgtgaa gatcctccgc tggcgggcac tgtcggagag
     8761 cctcgcgatc tccatcgtct ccgcgatgcg caccgcgtcc ttcaccccgt acacggtgaa
     8821 gaacttctcc agatcggggc gctgtttacc attctcgatc ttgctcaagg cgggcgggcc
     8881 ggccaggccc aacagtttgg cggcttccgc gagattgagc cccgtccgca ctcgcatcgt
     8941 tttcaggatc gctccgagcc tccggcgcag catggtcggt ttggcgtcag acatgtgatc
     9001 acccccttct gcgagcgact ctaccgacat caactggctt ggcatatgcc aatgttcacc
     9061 ctatcgagtt ggtttgcccg gcgtaagttg ctcgcgcgat tcgcgcccgc ctcagaatga
     9121 ggtcgctgtc gagtgcggca gcgtggagcg aacccgggag gcccacggca atgacgtaca
     9181 gaaacggcgc gttcgtagtc gacacgcgcg agggatggat cgggcaagtg atcgacagcg
     9241 cgggcagccg cgtacacgta cgagcccccg gcggcggcgc cgaatgggaa gtgccgttct
     9301 ccgtcctgcg gttggcgacg cgcgaggagc gggacgaggt cgggctctgg ccgagaggca
     9361 cgcggtcgcg gaaggggtgc ccggaatgcc cggcgctgga gctcgcgtgg cgggacgccg
     9421 ccgaaggggg cgacaagctg aaggaggcga ccgcgctcgt cgcgctgcgg cgccacggcc
     9481 gggtggtgca catgctgccg ggaggcaggg cgtgagtacg gcggtggcga cgtgcgcgca
     9541 ccgcgcgggg tgggtgcggg gcaagggtga ggcgcggtgc gggagttgtg gggtggtgcg
     9601 cttcacggag tacggcgcgc tgcgcccgcc gggcctggcc gaggcggtga aaccgcccca
     9661 cggcgggagc gcggaccgtg cggccgcgct gtgggtgatg aggcggacgc ggcgccgtac
     9721 ggagtggtgg ggacgggccg tcaactgaca gtaatcctca cccatttggg tggatgaagt
     9781 gttgatcagg agtaattagg gggcgatatc gggaagttac ccggctgttg gggctgatca
     9841 cgttgggagg ggaatgtcgt ggagcagcag gaagaggtct acgagccgcc cgagttgatg
     9901 gaggtcggtg acttcgccga gctgacgctg ggcacgggca acggcacgta tttcgaaggc
     9961 ggctacgccc cgtggtacgt ccgaccgagc tgacgggacg ttgaccagtg aggcgtggtt
    10021 cgcggtcctt cccgacggcg aatccggggg caccgcggcg cgggcgctgc gtcgcggtac
    10081 cactgaggtg atcgaccacc actccggccg tccatggctg gtgggcagct ggccggccgg
    10141 gcaggtggtg gtcgccgcgg tgggtggtgc gcggctggcg gtgatcgggc ggtgtcccgt
    10201 caccaccgat gcgctggcgt cgaggctgag acgggtgcgg gatgtcgccg acgtcgaggg
    10261 ggcgctcgcg gggctggagg gcagcttcca cgcggtcgcg tcggtgggcg gccgggtcag
    10321 ggtgcgcggg agtgcctcgg ccgtgcggcg cgtcttccgg gcgcgggtgg acggggtgac
    10381 ggtggcggcg agccgtgccg atgtgctggc gcgggccgtc ggcgcggggg tcgacgagcg
    10441 ccgggtggct ctccacctgc tgtcctcccc gccgccgtat ccgctcgacg cgggtccagg
    10501 cctgtggcgg ggcgtcgagg cgctgcccgc ggggagcttc ctgctgctcg aagctgacgg
    10561 gcgcgccgag gtgcaccggt ggtggaatcc ccccgaaccc caactgtccc tggcggaggg
    10621 tgccgtcgag gtgggccggg cgctcaccgc cgccgtggat tcctgcaccg ccgacgccaa
    10681 gaccgtgagc tcggacctct ccggcgggat ggactccacc agcctgtgct tcctcgccgc
    10741 ccgtggccag gcccgcctgg tcaccttccg ctgggagagc gtcgacgcgg cgaacgacga
    10801 cgcggcctgg gccgggctgg cggccgcccg gctgccgggc agcgccgagc acgtggttcc
    10861 cgaacggtcg cgcgcgcccc tgtggttcag cggactggcc gacctggagg cggcggccga
    10921 cgaaccgggc agctgggtgc gcgacggcgc ccggctcgcc acgctcgtag ggctgatgac
    10981 cgagcacggc tcgcagctgc acctgtcggg cggcggtggt gacgagctct tctgtgcttt
    11041 cccttcgtat gtgcacgaca gcctccgcag tcacccgctg cccacgctcg gcctggtgcg
    11101 cagacagcga ctgcttcaga ggtggtcgct gtggcccctg ctccgggggc tggcggaccg
    11161 cagcacgttc agtcagtggc tggccgcctg ggccgacggc ctcaccggga cgcgtaggcc
    11221 gtcccccgcc cgtacctcca ccgcctgggg agcggacctg cggatgccgc cctgggcctc
    11281 tccggacgcg gtccgttccg tgcagagtct gctgcgcgcg gcggccgccg accttccgga
    11341 gccgctcgcg gcccagcgcg gccagcacgc cgccctgtcc tgtgtgcaga tgtgcggccg
    11401 tggcttccgg caggtcgatc aggtgacttc cgcccagggg ctgccgtacg ccgccccgta
    11461 tctcgacgac cgggtgatcg aggcggccct ctccgtacgc gtcgccgagc gcagtgcgcg
    11521 tgaccgctat aaaccggtgc tcgcgacggc gatgagcggg atcgttccgg acaccgtgct
    11581 ggcgcgctcc accaaggggg agtacagcgc cgacttccac ctcggcctgc ggcggaacaa
    11641 ggccgcgctc gcggagatcg tcgccgagtc ccgtctcgcc cgcgcggggc tcctggacgc
    11701 ggcggccctc cgcgcgagcc tgcggcgccc cgagctgtcg cccgacctga tgcgctcgct
    11761 cgacaacacc ctggcctgcg agatgtggct gcgctcggcg ctcggcgcgg gcggcccggg
    11821 tccggaggcg gtggtcggat gagcatccac caagttccgt actcccgtgg cttcttcgcc
    11881 cgcgccgggc ggcccgccgc gttcatggcc gcggccaccg cccggctgct cgtcctcctg
    11941 ccgccccggc ggatccgccg gatcctgtcg ttcctccgcc ggggcgccgc ccccgccacg
    12001 atggcgcagg ccctcgcggc ccggcaggcg gtcgtcgcga ccagcgcgcg ctgcgcgggc
    12061 gagggctgcc tgcagcgttc cgtggcgacc gcactgctgt gccgcctgcg cggcgtctgg
    12121 ccggactggt gcacgggcgt gcggacggcg ccgttccggg cccatgcctg ggtcgaagcg
    12181 gaaggcgagc cggtcggcga gccgttcccg gccggttact accgaccgct gatgagggtg
    12241 gcggccgggc gctgagcgcg agtgtttcag ccgattgtgg aaccgccgtc gccgatccgg
    12301 cgcaggtcgg tgatccgtcc cggtcggcga cgtggccggg ttgtgcgcac ccgcatccgt
    12361 acgggcgtcc gccgagcggg ccgtgggcac tatccggtgg cgtaccgcac atcgacggac
    12421 gcagagatga ggatgaacac aagcatggga tcgagacctg cgcgaagatt ctggtcgctg
    12481 gtgctggccg cggccgtcgg gctcatattc agttcccagt tcacggcgtc ggcgaccgtg
    12541 gcggcgccga ggagcgtcgg cggatcgccg ctgtacaccg cgcacgacgc gtccggccgg
    12601 gtgacggtca cggtgttcaa gaacgtcagc tccgactacc gggagatctg ggacaaccag
    12661 gaggtgaccg tcggcgacga cgccatggtc gccatcggcg gcggtgccac cgcggtcgag
    12721 taccccgcgg gcgccctgct gaccgcgtcc tatccgaacg attcgcgtac ggggtggatc
    12781 gtcagcgcga aggaccacgc gatcgcgcag tcctaccagc tcacgaccta cgtcatcggg
    12841 ctgaagatcg ccggcatgac ccgggacgag ctgaagaact acctggtcta caacagcgac
    12901 ggacaggcgt acggttcgac cccttcggcc tcgtcgcacc tgaactccga caccgacgtg
    12961 ctgctcggcg gcgggttccg gacctactgg aacgggtggg gtcaactggc caccggttcc
    13021 tacccgtcgg gcccggtgga gtggacggcc ggctcgaagg accatttgca cgcgtccccg
    13081 ggaaccatcc agacctgggc catcggcatc aagcggaatc ttccggtcgg ctggatcgac
    13141 acctacccgt cgtacccggt gccttcgggg gtgtcgaacc acccgtcggc gtcggcccgc
    13201 gtccagccgg ggtatgtgat gaccggcggc ggtggccagg tcaaatgcgc cggctggggc
    13261 tgcgcgctgt ggagtctgga gccatcgatc gacaactccg ggtatcagtc cttcaccgcg
    13321 cgcgccaagg accatgccga ggccgccacg ggtaccacct gggcgtggac catcgggatc
    13381 aggctcgtct gaccttgacg cttctctgac gccgacccgc cgtggccgga gcctggaggg
    13441 ggcgtagcct gtggagcaat ttaacgatct tgaaagctaa gagtgggtgt accgcatgaa
    13501 gttggcacgt gtgtccgccg tcgtcgtggc cgccgcgatc gctccggcgg tcctgctgtc
    13561 ctcgccgtcc ttcgccgccg gtggtgccgc caagtcgccc gccgccgtgt cgacggcgaa
    13621 gcagggcgag accaccaagg tctccgacat gtcggacgac gacctgcggg tcgcggtgct
    13681 gacgatcatg ggcaagggcg gccgggccgt gaaggacgcg ggcaacgcgg cgatgaacgg
    13741 cactgtcgcg gacctgcgtc acttccttga ggtgggtcag ttccgggctc gtgaggagga
    13801 tgaccgcgtc gaggctttga cgatcatggg caagggtggt cgggctgtga aggacgcggg
    13861 cagccaggcg ctggacggca cccccgccga cgtacgccgc ttcatcgagg tgggtcagtt
    13921 ccgggctcgt gaggaggacg accgcgtcga ggccctgacc atcatggcca agggcggcaa
    13981 ggccgtgaag gcggcgggcg acaaggcgct gaagggcacc gccgccgacg tacgtcactt
    14041 catcgaggtc ggccagtacg aggcccgcaa gctcgacgag cagaagaagc ccaccgccaa
    14101 gaagcgctag ccaggggccc ggtccggcgc tagcgcacgg cggcgaccgg gggcgcctcg
    14161 gtcgccgcac gtgcctgaag ggcttcctgg ggggcttctc ggggagccct tctcggcgtg
    14221 cgcagccagc gggtgcgcgc cccgaggacg ccgaggccga gggccaccag gtgcccggcg
    14281 tcggccagtt cgtggttgac gatccaggcg acggtgagcg ccgcggtgag ggccgggagc
    14341 ccgtagcggc gggcccggtg gccgccgagg gcgagcaggc aggcggcggt ggccaccagg
    14401 ccgtaactga tcccgacgtc acgggccctg gccaggacgc ccggcaggtg cgcgaggtgc
    14461 atcagccaca tggcgccctc ggtcagcagg gtcgccacga ggtggcccag caggaacaca
    14521 ccgaacccgc gcagcgaccc ccaccgccac tccgccagcc cgagcaccgc ggccacggcg
    14581 gcgatcccga gcagcacggg cacaccgtcg accaccagcc cgctggtgaa cagcgtccac
    14641 cacttcccga cctccaggtg gtggacgttg ctgctgttgt gccgcacgaa ccgcgcctgc
    14701 tcgcgcagtg actggctgga catccacgcg gcggtggtga ccagcagcgc gacgtacgcc
    14761 gtcgtcgcgg gcagccgccg gacggcgcgc accatgttgt tcccgaccat cagggaactg
    14821 taggcgagac gcgtgtcatg ccgcggtaag ggccgtcggc agtgccgcta gtacagggcc
    14881 tcgcccatcg gggagctgtc gccgacgatg taggcgcgga tcgacgcgag gtacgcggcg
    14941 cggcccaccc ggccgtcgcc gtcggcgtcc agcgcgtcga acgcggcggc ggcgttcccg
    15001 ggcgggttgt tcagcgcggt gcgcagcgtg gtgaactcgg ccttgtccag ggcgccgtcg
    15061 ccgtccgcgt cgacgaggtc gaagagcgcg ccgagcgcga agcggcagat gttgtcgaac
    15121 ttgtcggcgc ccacccacgc gttgtactcg tcgaaggtca gcttcccgtc gccgtccgcg
    15181 tccatctcgt cccaggcctt gaggcctgcc gcgcgggcgg cgacgacaag ggggtcatct
    15241 tccatgcgct ccgtggccag gacggtccgg tcgatgcggg agaggtagtc gtgccgtgtg
    15301 acgacccggt ccccgtcggc gtccatcatg gcgaacacgc gcactctcgc ggcagtggcg
    15361 gctgtggcag tcgtacggct cactcgggtc tcctcctggt cggttcgtga tcccgctcga
    15421 cgaggggtcg tccgacgcct cctacccggc gcgtcccggg tgccaagcgg gtcgccggga
    15481 gggggtgggc gtgcgcgaca gtgcgccgag gcggacacgc gccggtggcg cgcttcgaga
    15541 cactggatca gccgatgcgg ccccggggta ggcaagtgcc cataaaagag cacaacttgc
    15601 tggaggggaa tgtgtttcga ggccgcggta cgacggtgat gctgggatcc ctggccctgg
    15661 tggtctcgtc gctggtgtgg gcgccggccg gtcgggccgg gacgggcgag tacgaggccg
    15721 tcacctgtgt gggcaatgcc cacggacgct acgacccgcc gctcaccctc cggccccagg
    15781 agacccgcat ccacgccgac gtgcgctaca cctgcaccac tgcccccggc cacaccgtcc
    15841 cggcgacagg ctccttcgac gccgtcgcgc ccacggcgtc ctgcctctcg ctgtccggcg
    15901 ccggcggtac cgagaccatc cgctacgaag gcggcggccg gtcggtgatc gtcatcgacg
    15961 gtgtcaccgc ccgcgccgtg ggcttgctgg acgcccaaca gtcgggccgg gtcaccgagg
    16021 gccgcggtga aggccacttc gtacgccgga ccgtgacctc gacaccccgg caatcgccca
    16081 cggactgcct cgcctccggc ctccagggca cttggagcgc ggttcagctg gagatcctgc
    16141 cgtagcgccg acccggccac tcggcgatcc gccgcctctg attggcccat gatcttcgat
    16201 gggaaatgga cctgcccgat gggccgttcc gcgccatagc ctcatgggca tgacacacaa
    16261 agccgacttc tacttcgacc ccatctgccc cttcgcctgg atcacctccc gctggatcct
    16321 cgaggtggag cgccaccgcg atctcgatct gcggttccgc gtcatgagcc tgtccgtcct
    16381 caacgagggc cgcgccgacc ttcccgagcg gtaccagcgg ctgttcgacg tgggctgggg
    16441 gccggtgcgg gtgtgcatcg ccgcggcgcg cgagcacggg gagcacgtac tgcgcgatct
    16501 gtacaccgcc ctcggcacgc gcatccacga cgccgaccgc gaggtctccg acgccctcat
    16561 ccgggaggcg ctggccgagg ccggccttcc ggaggcgctg gccgacgcgg cgcacaccac
    16621 ggagtacgac gaggaactgc gcaagagcca ccacgagggc atggacccgg tcggcgagga
    16681 cgtcggcacc cccaccttgc acgtcgacgg tgtcgcgttc ttcggcccgg tcctgaacgc
    16741 gataccgcgc ggagaggaag ccgcccggat cttcgacggc gtacgactgc tggccggcaa
    16801 cccgcacttc ttcgagctca agcgcactcg cacgggcggt ctggacttca gctgacgcac
    16861 tcacggtccc accgcgaagg gggcgtcttg ggggccggag cgcacctctg ctcagtggcg
    16921 cggctccgct gaacagaacg cgtccgcacc cggccgctca ccccgtacca ggaacttcgt
    16981 caccgcccgg tccccgcacg cgttcccgtt gtccagatac accccgtgtc cacccgcgtc
    17041 caccgtcacc atccgagccc gctccccgaa cgcggcgcgc atcttgagtg cccccctgta
    17101 cggcgtcgac gggtcgcgca ggttctggat catgaggacg ttggacgggc cgttcggtgt
    17161 gatgcgggtc ggcttgtcgg ccgagggcgt cttccagaag gcgcagggga ggatgcccgc
    17221 cggcatgccc gccgtgaggg ggtggcgggc gcggtcggtg gcgacggcgc gggcgtacga
    17281 ggggatcgag cgcggccagg tgccgacgtc gttgcacacg acaccggcga agacggccgc
    17341 gtcggactgc gacaggggct ggggcgccgg gtctgcgacg gtcagcgggc cggtccccgt
    17401 gcgggcggcg cggatcaggt cggcgaggcg ggggaaatcc gcgtcggagt agaggctgtt
    17461 ctgcatgacc tgccgcagga ggttgccggt cagctcgtgc ccggtgtcgg cgaactcgcg
    17521 cggctcgcgg tccagcccgg ccgccagcgc gaggaacatc ggccgcacgt ccgccgcctt
    17581 cgcggccagc cgctgatcgc cgcgcgccgg gtcggccgcc cactcggcga agtcggggaa
    17641 gcggtcgtcg gcggcgcccg acatgttcgc gagccagccg cgctccaccc gctccgggtc
    17701 ggggtcgccg ctgctgtcga gcacccaacg gtcggtgtgc tgcgggaact tctgcgcgta
    17761 cacggcaccc acgtacgtac cgtacgaaac gcccaaggcc gacagcttct cctcgcccag
    17821 cgcctgccgg aagcggtcga ggtcgcggac ctcgttggcc gtggagaggc tgcgtacgag
    17881 cgcgccgccg ttgcgggcgc acgcgtcggc gacccggcgc gcgcgggcga cgttggcgct
    17941 gatgtcgccg tcgggcccgg gccaggggcg gaggttgacc ggccgccggt cgtcgtcgga
    18001 gatgccgcag tcggcctggg tgctgccgcc gacgccgcgc gggtcgagcc cgacgatgtc
    18061 gtacgcgccg ccggtctcct tgcgcagctg cgcacccctg cgggccacct cctcccgccc
    18121 ggagccgccc ggtccgccgg gtatcagcag cagcgtgccg cgccgggcct ccgggtggtc
    18181 gctgcgcagc cgggacacgg cgatgtcgac agtcggcccg ccgggacggc tgtagtccaa
    18241 cggcatggga aggacggcgc actcgcgccc gtccttctcc gcgcagggct gccaggtgag
    18301 ccgcggcgcc ttcgcggtgg gcgtggcggc gtgggtggga gcggtcagag tggcggcgca
    18361 ggcggcggcg gagagggtgg tcaggagggc tttacgtgtc aacggtcgca tggggtaagg
    18421 gtgatgcggg cggggcccgc ctgcccatcc ggccagccgt tccttgaagg gtggggataa
    18481 ccccctcctt tcaggcctgc ccggcttcgc ggagccccgg ggctgtgccc gcgggccacc
    18541 tctcgaacca tcgctgatcc gcttcgagtt gcgccgccag tgagatcagc agcggctcgc
    18601 tcgactccgg tccgagcagc tgcgcgccca tcggcaggcc ctcgtccgtg aggcccgccg
    18661 gtacgctgat ccccggccac cccagcacgt tccacggcca cgcgtacggg cacgcgccga
    18721 tcatcgcctc gtccgtgtgc cgggtggaga ggccgtccag tgcgccgatc cgcaggggcg
    18781 gtacggccgt tgtcggcgtc aggagcacgt cgaagcgccc gaagagctcg ccgacccggc
    18841 ggcgcagcgg gccctccgcc gcccgcgcgg cccgcaggag ggggccgccg agcagccgcc
    18901 cgttccgcgc gttcgcgttc gtacgggggt cgaggagcgt ccggtcgggg gcccgctccg
    18961 cccagtcgcg gatcccggcc atcgagcgcg gtacgaaggt gagcccgatc ggtccgtagc
    19021 gcggctccgc ctcgaccacc tcgtggccca gcgccgccag ccgctcggcg atccgcaggg
    19081 tcgcggaccg tacggccggg tccagccact gccgggccac ggcgtacgcg ggccggaagg
    19141 acagcgcgat ccgcagccgc cgcggttccc ggcccgccgc cgcgagcagg tcgacggcgg
    19201 gcggccggtg caggtcgccg cggtgcgaac cgctcaccac gtgcagcagc agcgccgcgt
    19261 ccgcgaccgt acgggccagc gggccgtgac aggtgatgcc gtggaaggac tccggctccg
    19321 gccaggtcga gacgcgcccg cgctgcggtt tgatgccgac gaggtgcgac caggccgcgg
    19381 ggatgcgcag cgaaccggcg ccgtccgagc cgagcgcggc cggcaccagg cccgcggcga
    19441 ccgccgccgc tgccccgccc gacgacccgc cgggtgtgtg ctcgtggctc cacgggttgc
    19501 gggtggcgcc gaaggcgggg ccctccgtga cggggaactg tcccagttcc ggggtgttcg
    19561 tcttgcccac gatcaccgcg cccgcggccc gcagcctgcg gacggcctcg ctgtccgcgg
    19621 gccgtggcgg gaagtcgccc gcgcagccga acgcggtcgg ctccccggcc acgtccatgt
    19681 cgtccttcac cgccagcggc acgccgagga ggggcgcccg gtgccccgcc gcgagcctcc
    19741 ggtccgcggc gtcggcctcg gccagtgcgg cctcggcccg cacccgccgg aaggcgttca
    19801 gtacgggctg cgtctcctcg atgcgtcgca gtgcttcttc cacgagcgtc cgcgaggtca
    19861 cgtcccccgc tgcgagcgcc cgcgcctgtt cgccgagtcc ggcggctgtg cggtccatcg
    19921 tgtgttcccc ttcccccgtt cgaacacacg ctagtagtgc gcgagttgtc cggaacagtc
    19981 acccgaaggc cagaggcggg gaggccggct acggcgccag aatgtccagt tccgccatcg
    20041 cgcccgccgt gatctcgcgg gtgagggcct ccgcgcggac ggagtcgtgt tcgcgtacgg
    20101 cctccgccac gcgtacgtgc agggtgaccg ccgccgggtc ggggtcggtg aacatgacct
    20161 cgtgctgcgt gcggcccgtg aggacctcgg cgacgacgtc gcccaggcgg gcgaacatct
    20221 cgttgcccga ggcgcgcagg atcacgcggt ggaaggcgat gtcgtgcacc agatagccgg
    20281 ccagctgctg gccgcgcgag gtggcgacca tgccgagggc gtgctcggtg agctcggcgc
    20341 actgcgcggg ggtggcgagg cgggcggcga gcccggcggc tacgggttcc acggcggagc
    20401 ggagcacggt gagcgagcgg agctggcgcg gccggtcggc gccggcgagg cgccagcgga
    20461 tgacccgcgg gtcgtagacg ttccactcct cggtggggag cacggtcacg ccgacgcggc
    20521 gccgcgaggt gaccagccgc atggactcca ggacgcggac ggcctcgcgg acgaccgtgc
    20581 gcgagacggc gaaccgctcc tccagctcgt cggtgcgcag caccgtgccc ggtgcgtact
    20641 cgcctgccgt gatcgcgggc ccgagggatt ccagcacgcg cgcgtgcagc ccctgcccct
    20701 ggttttccat ggggtcagcc tacggtttcc ggggaccggc aattaagtat gacttttagg
    20761 tcacaggggc ttgaatacgt cgtaccaatg agcttgagtg agccgcatcg ccgacgacgt
    20821 cgaggtcgga cgtcgaggtc aatggagaca gcgaggtagc gatgcaggcc ccccacgccc
    20881 cccacgtcgt ggccgtcatg ggagtgtccg gtacgggcaa gaccacgatc ggccccctgg
    20941 tggcggacgc cctcggtgtc ccctacgccg agggggacga cttccacccg ccggccaaca
    21001 tcgccaagat gtcgtccggc accccgctgg acgacgccga ccgcgccccc tggctggacg
    21061 ccgtcggcgc ctgggcgcac agccgcgccg ggctgggcgg ggtcgtcagc tgctccgccc
    21121 tcaagcgcgc ctaccgcgac cggctgcgcg cggccgcccc cggcatcgtc ttcctccacc
    21181 tcaccggcga ccgcgcgctg atcgccgagc ggatggccgc ccgcaagggc cacttcatga
    21241 cgggccggct cctggactcg cagttcgcga ccctcgaacc gctcgaagcg gacgaggcgg
    21301 gcgtcgccgt ggacgtcgcg cccggccccg aggccgtcgc cgagcgcgcg accgccgcac
    21361 tgcggaagct ctgacccttt ccctcccccc ttaggaagcc ccgtgagcac tctcagcgtc
    21421 gagatgctgg ccgcggcccc cgccggaccg atcacttcgg cgggtcacgc acagctcggg
    21481 atcgccgtcc tcgtcggcat cgccgtcatc gtcctcctca tcacccgcct gaagctgcac
    21541 gcctttctgg ccctgaccat cggctcgctg gtgctcggcg ccgtcgcggg cgccccgatg
    21601 gacaaggtca tcaccagctt caccaccgga ctcggcgcga ccgtcgcggg cgtcggcgtc
    21661 ctgatcgcgc tcggcgcgat actgggcaag ctgctcgccg actcgggcgg cgccgaccag
    21721 atcgtggaca cgatcctcgc ccgcgcgagc aaccggacca tgccctgggc gatggtgctg
    21781 atcgcgggca tcatcgggct gccgctcttc ttcgaggtcg ggatcgtgct gctgatcccg
    21841 gtggtgctgc tggtcgccaa gcgcggcaac ttctccctca tgcgcatcgg catccccgcg
    21901 ctggccgggc tctccgtgat gcacggcctg gtgccgccgc accccggccc gctcgccgcc
    21961 atcgacgcca tcggcgccaa cctgggcgtg accctggcgc tcggcgtgct cgtcgccgtg
    22021 ccgaccgccg tgatcgcggg gccgctcttc tcccgtatcg ccgcccgctg ggtggacatc
    22081 gccccgcccg agaagctcat cccgcagcgc ccctcggagg agctggagcg ccgccccggc
    22141 ttcgccgcca cggtgggaac ggtgctgctg cccgtcgtgc tgatgctcgc caaggcgctc
    22201 gtcgacatcg tcgtcgacga ccccaaggac cacgtccagc gcgtcaccga cgtca
//
