LOCUS       NZ_CP031455            22673 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces olivoreticuli subsp. olivoreticuli strain ATCC 31159
            chromosome, complete genome.
ACCESSION   NZ_CP031455
VERSION     NZ_CP031455.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivoreticuli subsp. olivoreticuli
  ORGANISM  Streptomyces olivoreticuli subsp. olivoreticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Complete genome sequence of Streptomyces olivoreticuli ATCC 31159,
            producer of anticancer bestatin and diverse secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2018) Tianjin Key Laboratory of Food
            Biotechnology, College of Biotechnology and Food Science, Tianjin
            University of Commerce, NO.409 Guangrong Road, Tianjin, Tianjin
            300134, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-JUN-2018
            Assembly Method                   :: SMRT Link v. 5.1.0
            Assembly Name                     :: TJCU_BT_311
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: SMRT Link v5.1.0
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003391135.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 04:49:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,459
            Genes (coding)                    :: 7,276
            CDSs (with protein)               :: 7,276
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 183
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 183
            Pseudo Genes (frameshifted)       :: 61 of 183
            Pseudo Genes (incomplete)         :: 150 of 183
            Pseudo Genes (internal stop)      :: 18 of 183
            Pseudo Genes (multiple problems)  :: 41 of 183
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:12:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3432700
            Orig. end                         :: 3455373
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031455.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Hongyu Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22673
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="26"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22673
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22673
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12673](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12673)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(289..831)
                     /locus_tag="DXZ73_RS14570"
     CDS             complement(289..831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987261.1"
                     /locus_tag="DXZ73_RS14570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_116211421.1"
                     /transl_table=11
                     /translation="MNRRSVIAVPLVCGLLLVGTGCGGGGKKKEAESTGGPTPTSSAER
                     QKFAKTRFVTNAGLAAGAAYQWVIKPYRNGAFKKGADGRTVALVKAGLAGTFSYNRFKA
                     AVNNAKGDPTLSKAVAPLSAGIDSLKGLTTKFRKGDATDNDANDFDKVINNVKDAGKGA
                     GAPVTDQVPSYSDIQKG"
     gene            complement(945..2024)
                     /locus_tag="DXZ73_RS14575"
     CDS             complement(945..2024)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004953108.1"
                     /locus_tag="DXZ73_RS14575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase"
                     /protein_id="WP_116211422.1"
                     /transl_table=11
                     /translation="MTRAGRRPDRTERLVLPGVLTADQAARTVAGIAAVQREDGAIPWF
                     RGHHLDPWDHVEAAMALDAAGEHDRAEAAYRWLADHQNPDGSWYAAYADGDAAEPTDRS
                     RETNFVAYAAVGVWHHYLATGDDAFLDRMWPTVFAAVEFVLQLQQPGGQIGWKREEDGT
                     DVTDALLTGCSSMHQALRCALAIAEHREEPQPDWELATGLLAHAIRKHPERFLDKSRYS
                     MDWYYPVLGGALTGPAAKERIEEGWDDFVVPGLGVRCVLPNPWVTGGESCELALALWVM
                     GESDRAVEILQWIQHLRAEDGLYWTGYVFEDDAIWPQELTAWTAGSLLLAVAALGGDEA
                     TTAVFSGERLPVGLDPDCC"
     gene            complement(2021..2794)
                     /locus_tag="DXZ73_RS14580"
     CDS             complement(2021..2794)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004953106.1"
                     /locus_tag="DXZ73_RS14580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_116211423.1"
                     /transl_table=11
                     /translation="MLTVDFSRFPLAAGDRVLDLGCGAGRHAFECYRRGAQVVALDRNA
                     EEIREVAKWFAAMKEAGEAPAGATATAMEGDALALPFPDESFDVVIISEVMEHIPDDKG
                     VLAEMVRVLKPGGRIAVTVPRYGPEKVCWTLSDAYHEVEGGHIRIYRGDELLDKMREAG
                     LAPYGTHHAHGLHSPYWWLKCAFGVDNDKALPVRAYHKLLVWDIMKKPKATRVAEQLLN
                     PVIGKSFVAYATKPHAPAGTQDRDTAAAASAEERA"
     misc_feature    complement(2776..2790)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     gene            complement(2907..4280)
                     /locus_tag="DXZ73_RS14585"
     CDS             complement(2907..4280)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010637585.1"
                     /locus_tag="DXZ73_RS14585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_116211424.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.4e-30,
                     bitscore: 103.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEATEAALAHDDHPVDGGGDGPLRIALLTYKGNPFCGGQGVYV
                     RHLSRELARLGHHVEVIGSQPYPVLDGDGADGAVGSGRVSLTELPSLDLYRQPDPFRTP
                     GRDEYRDWIDALEVATMWTGGFPEPLTFSLRARRHLAAHRGRFDVVHDNQTLGYGLLGG
                     PTALGAPLVTTIHHPITVDRQLDLAAAADWKRRMSVRRWYGFTRMQKRVARRLPSVLTV
                     SGSSRQEIVTHLGVSPGRVHVVPIGADTDLFSPDPSVAEVPGRIVTTSSADVPLKGLVH
                     LVEALAAVRAQNPGAHLVVVGKRAEDGPVASAIRRHGLEGAVEFVKGITDAELVDLVRS
                     AQISCVPSLYEGFSLPAAEAMATGTPLVATTGGAIPEVAGPDGETCLAVPPGDPGALAA
                     ALNRLLGDEALRRRLGAAGRERVLSRFTWRQAAIGTAERYRAAIALSAGASVPTGRRG"
     misc_feature    4335..4348
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.98"
                     /tool="antismash"
     misc_feature    complement(4343..4357)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            4500..5147
                     /locus_tag="DXZ73_RS14590"
     CDS             4500..5147
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006605918.1"
                     /locus_tag="DXZ73_RS14590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_116211425.1"
                     /transl_table=11
                     /translation="MTTDSRSAPTAPSSLPRPLLTERQEARRRRILQATTRLATRGGFD
                     AVQMREVAESSNVALGTLYRYFPSKIHLLVATMQDQLQQLHETLRKRPLTDEDPAARVA
                     QTLMRAFRAMQREPHLADAMVRALTFADRSVSSEVDTVSRLTTAIILDAMGPAGASGPP
                     TPEQLSAVRVIEHTWHSALITWLSGRASIAQVKIDIETVCRLIDLTNPNSPR"
     misc_feature    complement(5296..5308)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.62"
                     /tool="antismash"
     gene            5385..5996
                     /locus_tag="DXZ73_RS14595"
     CDS             5385..5996
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142169.1"
                     /locus_tag="DXZ73_RS14595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_116211426.1"
                     /transl_table=11
                     /translation="MIRVLLVHDTHLLRAALAALIAREPDLEVSASSWTHSVAKSRVLL
                     PHVCVVDMDSPEAGGPYGLRELSAWCDAGDGTSALLALATAERPGPLRRAYEERVLGYL
                     SKNASPGRLIEGIRHVAKGERYIDESLGYSFLQASDIPLTRRELTVLSLAAEGASIGEI
                     ARSLHLSNGTVRNYMAAITRKTGARNRVDAIRISRVAGWV"
     gene            complement(6043..7731)
                     /locus_tag="DXZ73_RS14600"
     CDS             complement(6043..7731)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018852154.1"
                     /locus_tag="DXZ73_RS14600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_116211427.1"
                     /transl_table=11
                     /translation="MTTDTPSLIRRGVTFLAAHRRAIARLTAWSAVEAAHTFAMGYALA
                     KALDGGFLAGKPGEGLAWLGLAALAVVVGAFGTGRTYRGVAALVEPLRDRLVGRVVTRA
                     LREADGAAVSRLTHQVEIARDTFAGLVMVSRSFVFTAAGALVGLCLLAPVLLVVVAPPL
                     VLGLGLFLATLRPLARRQETFLATDEAIAQSLGEVSGGLRDITAGGAEPYVREQTGALV
                     DAEFRASLALARWSVLRVVALAVAGRLPLVLLLVTTPWLLDRGVTPGALVGALAYLTQS
                     LLPALQALVHGLGASGSRLAVVIRRLTDGPPLPPPPAVEWAPPESSPAAVELRGVTFSY
                     GEHAEPVLRDLDLVVPVGGRLAVVGPSGVGKSTLAGLVAGLLEPGSGEVRVAGGRAGRV
                     LIPQEAYVFSGTLADNLGYLRPDGVPDHELHAAADVLAMTELVDRLGGFGAPVTPAELS
                     AGERQRIALARAYLAPARIAVLDEATCHLDAEAEARVESAFARRTDGTLIVIAHRMGSA
                     RRADRVLVMDGARTVLGTHEELLGESELYRDLTAVVRPDRLGSTP"
     gene            complement(7985..9649)
                     /locus_tag="DXZ73_RS14605"
     CDS             complement(7985..9649)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998778.1"
                     /locus_tag="DXZ73_RS14605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_240351735.1"
                     /transl_table=11
                     /translation="MLDTARHSAARALTLTLLGLASTAVALALPAALGHTLDLLLARRG
                     GASGWVLLCTALICAPAALDALDGLLAGTTTARATARLRHRLLCHVLAAGPRATARFAP
                     GDLVTRLVGNAADAGTAPGTLAGAASSVVAPLGGIVALGLIDPWLAVAFLAGAPLLALL
                     LRALARASSDCVAQYQRLQGDIAGRLVEAVGGARTIAAAGTADRERDRVLEPLPALSGQ
                     GHRMWRVQGRAAAQAVTVVPLLQIAVLAVAGLRLNQGLLSVGDLLAASRYAVLATGIGM
                     LVGHLNAAVRARTAAGRLADVLSVPLPPYGPDVRRLPPGDGTLELRGVGAVRGGRHILR
                     DLDLVVPGGTSLAVVGRSGTGKSVLAALAGRLADPDSGVVTLDGVPLPRLGHDELRRAV
                     GYAFERPALLGGTIGGTVAFGVSDPGPDAVAAAARAACADGFVRRLPRGYATPCAEAPL
                     SGGEAQRLGLARAFAHAGRVLILDDATSSLDTVTEHEVATALVRDVAARTRLVVAHRAS
                     TAARADAVAWLEGGRVRAVGTHESLWRCAAYRAVFGG"
     gene            complement(9836..9967)
                     /locus_tag="DXZ73_RS14610"
     CDS             complement(9836..9967)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="DXZ73_RS14610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_116211428.1"
                     /transl_table=11
                     /translation="MALLDLQNMESEELHGGGGGEGGGASTVSLLSCVSTASILLCL"
     CDS_motif       complement(9905..9967)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQNMESEELHGGGGGE"
                     /locus_tag="DXZ73_RS14610_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9836..9904)
                     /prepeptide="core"
                     /locus_tag="DXZ73_RS14610_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="13.30"
                     /molecular_weight="1926.3"
                     /monoisotopic_mass="1925.1"
                     /core_sequence="GGGASTVSLLSCVSTASILLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQNMESEELHGGGGGE"
                     /leader_location="[9904:9967](-)"
                     /alternative_weights="1944.3"
                     /alternative_weights="1962.3"
                     /alternative_weights="1980.3"
                     /alternative_weights="1998.4"
                     /alternative_weights="2016.4"
     gene            complement(10001..12673)
                     /gene="lanKC"
                     /locus_tag="DXZ73_RS14615"
     CDS             complement(10001..12673)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014142173.1"
                     /locus_tag="DXZ73_RS14615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_116211429.1"
                     /sec_met_domain="micKC (E-value: 4.1e-231, bitscore: 768.2,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 3.7e-09, bitscore: 35.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.4e-05, bitscore:
                     20.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYCLADRHFYETPDRLSAAGEGAEGTGPGALFETARRPV
                     PAGWDTARSGDWLHLLPLDDTGGPRPGQPLQGWKIHVSATADTADKTAADVWDYCVERG
                     IPFKFVPGPHLLHLRNTKYAGRDHSGKFITVYPADEEQLRTTLTELHGIVGGRPGPYVL
                     TDLRWHEGPLYVRYGAFARRFCVDERGTLVPAVENGEGQLVPDPRTPAFQVPAWVTLPA
                     FLEPHLAARNATTVGDIPYRIEKALHFSNGGGVYAGTDTRDGRKVVLKEGRPHAGLASD
                     GADAVARLEREKAALERLTGLGVAPEVRDWFTLGDHSFLVMDHIEGRTLNSFFSERHPL
                     LAAQPDPAATADYTAWALRIHRAVQEAVDAVHARGLVFNDLHMFNIMVAPDERSVALID
                     FEAAAPAAEHGRQVVAHPGFFAPPDRRGADVDRYALACLRLALFLPVTMLFVIDRGKAA
                     HLAEVIAEQFPVPREFLDEAVAEITRDAPVAEVPGKQAGMAPRAGRADDAPVLPEAGDW
                     PRSRDSMVRAILASATPDRDDRLFPGDVAQFTDGGGLGLAHGAAGVLHAFAETGAERYE
                     EGERWLLDHTDPLPPGTPLGLYDGIAGVALTLDRLGHTGRALDLTTTVLGEKWQRLTSD
                     LKSGLAGIGLALDHLARTTGERQLHDRALEAAQLLADRLAADAAAPGDRTRRRAGLTRG
                     GAGQALLFLRLYERTRAPALLDLAGTALRADLDRCVRRENGALEVDEGWRTMPYLGDGS
                     VGIGMVLDDYLALCPDPDPSFAEAREGILTAARSRFYAQPGLFQGRAGMILHLSRTTTP
                     GADPEHLAAQVRALSWYSMAYEGELAFPGSQMMRLSMDLTTGTAGCLLALGAAHGDARL
                     PFLAPPRAPRSRLHAVVEP"
     gene            complement(12836..13060)
                     /locus_tag="DXZ73_RS14620"
     CDS             complement(12836..13060)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS14620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116211430.1"
                     /transl_table=11
                     /translation="MVELPPFHGLVDAPPVPHTGGPPSWPTREECGLCSRYQATVEQAD
                     ELGYPAHAASYRTAWDRHCAEIAHKEMAV"
     gene            complement(13126..13281)
                     /locus_tag="DXZ73_RS38110"
     CDS             complement(13126..13281)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS38110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162890170.1"
                     /transl_table=11
                     /translation="MPCFPGTAVAPPLSRPTLQQRLKSQHPLVEEPPEARTEEEGDASP
                     AETDAP"
     misc_feature    13438..13453
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.09"
                     /tool="antismash"
     misc_feature    complement(13439..13452)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.88"
                     /tool="antismash"
     gene            13603..14472
                     /locus_tag="DXZ73_RS14625"
     CDS             13603..14472
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138945.1"
                     /locus_tag="DXZ73_RS14625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_116211431.1"
                     /transl_table=11
                     /translation="MPTVPLVPTLRRRRLGEALRRFRNEAGLTIEQAAALMGWDNSKLS
                     RIENAKVHIRPVEAAKLLGTYGVDAPDILMAIEILAKDAGKKGWWTTYGSVVDAHIKDY
                     LSLESDAESTRICSMGLIPGLLQTGGYAREIIAASSFWRPQEEVTALAEVRKARQSVLT
                     TRDGRPPLNFWAVIHESVLHQRFASRPTIMRDQLRHLLDMAELPNITIQLLPMAMAPHP
                     GMVGLFEVVRFPAPWPTVILTENLVGGQFVEGTEHVGLFEKAFERIVAAALPVDDSREI
                     IKNIMEKG"
     gene            14475..14693
                     /locus_tag="DXZ73_RS14630"
     CDS             14475..14693
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014138944.1"
                     /locus_tag="DXZ73_RS14630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_116211432.1"
                     /transl_table=11
                     /translation="MDHKEDLYGLDLCGATWRKSPDSNGGQSCVEITDLPDGGMAVRDS
                     KNPERPDLRYTADEWAAFRSGIINGTL"
     gene            14782..15591
                     /locus_tag="DXZ73_RS14635"
     CDS             14782..15591
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS14635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162890171.1"
                     /transl_table=11
                     /translation="MRRSIILAGAVVLLCSACSGSGAASKETKRPAAGAAGVHDAAVQA
                     AVGATTKSSARIDEQVEWTDGTRGYTVIVKGGFDLASGKGRLTAKIPGQSTIGPYDEIF
                     TRDTVYLRMPLEINDDPAWWSVSRDKVETHNVLRAPVNDPEHVLRQVARMRETSKVGEE
                     QVDGAPTVRYRGKLDNETLTLRLTEDRREEISIARKGLGSDLPASADVWIDRSGRVARI
                     RFELIMGTGSVTTTMYLTDHGKPVEAPVAPGGAKPLPLAALGGPLTG"
     misc_feature    14818..14820
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15817..16347)
                     /locus_tag="DXZ73_RS14640"
     CDS             complement(15817..16347)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS14640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116211434.1"
                     /transl_table=11
                     /translation="MRLRFGVLAVAAALGVGLVTGATPDAVAAQGEFIYTEPSEPRVLP
                     DPEATCYPYLGADGLARNETDQVVELFDENNCSGIPQHMAPRDHREVAFKSLRFHHRAR
                     GDFEYTVPGKQKSKYDPSDNHCYDIAGQGYTANLTNRDVLLYPRAGCVGSSYALRRHET
                     TRGADFQSMEFVN"
     gene            complement(16344..16652)
                     /locus_tag="DXZ73_RS14645"
     CDS             complement(16344..16652)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS14645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116211435.1"
                     /transl_table=11
                     /translation="MKRLVMAAAAVGAAAVLAVGLAGSAQAAEGTFVYTTPKGDTDSLS
                     NPRNDHCFNIVGDGHTVNSTDKLALLYDRADCHGEAKHHLDRDKQGWMKFKSVEFVS"
     gene            complement(16845..17480)
                     /locus_tag="DXZ73_RS14650"
     CDS             complement(16845..17480)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS14650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116211436.1"
                     /transl_table=11
                     /translation="MFKSKDEFVKAAKAAEKIYKEAGLGKSWDGHDAFSAERVGVAWCV
                     YSAVLKARKDLGPQFLGLVIGGLRTEEDPEQQGAGIDPKVKKNFGTMDETTKQFAQMGC
                     VLDSKRWSVLVNDSWLLAGVHDAQEFFLASPRTEANVFDFAEGRLRVFGRELAGLRAFG
                     YKFMDSPWPRLGEVEASGGGGLTADFIEYQKKAAEYQKNDKWRELLKK"
     misc_feature    complement(17298..17300)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17436..17445)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    17653..17668
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.95"
                     /tool="antismash"
     gene            complement(18213..18449)
                     /locus_tag="DXZ73_RS14660"
     CDS             complement(18213..18449)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018539159.1"
                     /locus_tag="DXZ73_RS14660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ferredoxin"
                     /protein_id="WP_116211437.1"
                     /transl_table=11
                     /translation="MPADAERWRVTVDRAVCVGSGLCAATAPGAFHLDEARRSHPVEEE
                     TPASEAVLEAAESCPVEAITIRSAEGVVFPPEE"
     gene            complement(18449..19906)
                     /locus_tag="DXZ73_RS14665"
     CDS             complement(18449..19906)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381665.1"
                     /locus_tag="DXZ73_RS14665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aldehyde dehydrogenase"
                     /protein_id="WP_116211438.1"
                     /sec_met_domain="Aldedh (E-value: 4.3e-154, bitscore:
                     512.2, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQFIEHGKLFIGGTWADPAGTDTIDVVSPHTETVIGRVPHASRE
                     DVDRAVAAARTSFDSGVWAQTPLAERLDVVTRIKDGIAARHEEIARVISAQNGSPCSWS
                     VLAQALGAMMVWDCAIGVARDIPYEERRAGVLGPLLVRREPVGVVAAVAPWNVPQFVAA
                     AKLAPALLTGCSAVLKPAPETPLDAYILAEIAAEAGLPEGVLSVLPAGREVGEYLVGHP
                     GVDKVSFTGSVASGKRVMEVAARNLTRVTLELGGKSAAIILPDADLEAAVAGIVPSAWM
                     NNGQACVAQTRILVPRVHYDELAGRFAAAADALVVGDPLDPATQVGPLVAERQRRRSLD
                     YIALGQREGAKVLAGGGRPAAPGHGWYVEPTLFGEVTNTMRIAREEIFGPVICLLPYED
                     EEEAVRIADDSDYGLSGSVWTSDVERGIAVARRVRTGTYSVNTFSLDMLGPFGGYKNSG
                     LGREFGPEGFAAYQEHKMIHLPAGYEG"
     gene            20026..21063
                     /locus_tag="DXZ73_RS14670"
     CDS             20026..21063
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170: metallo-beta-lactamase family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019885944.1"
                     /locus_tag="DXZ73_RS14670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_116211439.1"
                     /transl_table=11
                     /translation="MPQVTDHGGGVVSIPVPIPDNPLGHTLVHLLDTDRGPVLVDTGWD
                     DPASWDTLVAGLGACGTSVTELHGVLVTHHHPDHHGLSARVREVSGAWIAMHPADADLV
                     RRLRAAPPGQWLDQLVAKLVAAGAPEEHLAPVEAARARGRARPLPGSRAALPDREIAPG
                     ELLDLPGRRLRAIWTPGHTPGHVCLHLEEAHPLGRAGRGRLFSGDHLLPGVTPHIGLYE
                     FPGGPTATDPLGDYLASLERVALLGPAEVLPAHQYAFTDAPGRVATLLAHHRARLASLR
                     ALLATPRTLWQLTESMEWNRPWSRIPYGSRNIAVAEAEAHLRHLVALGHAEAVPGGPPV
                     TYVAV"
     misc_feature    complement(21115..21127)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.54"
                     /tool="antismash"
     regulatory      21138..21225
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(22041..22052)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    22197..22216
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: medium, score: 23.97"
                     /tool="antismash"
ORIGIN
        1 actcgacggt gaggcccccg gcgggcgcct cgaactcggt ggccctcgtc cgcacgagcg
       61 tctccgcgaa ccggtgcgcc cggcccacgt gcagcaccag ctgggccagc gtccagtccg
      121 ggcaggtggg cacggtggcg gagagatcgg cgccacgcag cgcgtcgcgc agcagcgcgg
      181 tctgggcgag gacctcggaa cagtaatggt cgtgggtgaa agtcgtcatg ccgtcactgt
      241 aaagagggcc actgacaacg cccttgccca gggaagccgt tcgcgccgtc agcccttctg
      301 gatgtcggag taggacggca cctggtcggt gaccggggcg cccgcgccct tgcccgcgtc
      361 cttcacgttg ttgatgacct tgtcgaagtc gttggcgtcg ttgtcggtcg cgtcgccctt
      421 gcggaacttc gtggtcagcc ccttgagcga gtcgatgccc gcgctgagcg gcgccacggc
      481 cttggagagc gtcgggtcgc ccttcgcgtt gttcacggcg gccttgaagc ggttgtacga
      541 gaacgtgccc gcgagccccg ccttcaccag ggcgacggtg cggccgtcgg cccccttctt
      601 gaaggcgccg ttccggtagg gcttgatgac ccactggtac gccgcgcccg cggcgagccc
      661 ggcgttggtc acgaagcgcg tcttggcgaa cttctgccgc tccgcggagc tggtgggggt
      721 gggcccgccg gtgctctcgg cctccttctt cttcccgccg ccgccgcatc ccgtaccgac
      781 gagaagaaga ccgcagacga ggggcacggc gatgacggag cggcgattca cggtgacctc
      841 cggtgggtgc ggtatccctc cggaaagggt cccgcccgcg ccgcacgctc cgccaccggg
      901 aagacccgtt cgagtggcaa cgggcccgtg ccctcagaac ggacctagca gcaatccggg
      961 tccaggccga caggcagacg ctcgccgctg aagaccgccg tcgtcgcctc gtcgccgccc
     1021 agtgccgcca ccgccagcag cagggagccc gccgtccacg ccgtcagttc ctgcggccag
     1081 atcgcgtcgt cctcgaagac gtagccggtc cagtagaggc cgtcctcggc ccgcaggtgc
     1141 tggatccact ggaggatctc caccgcgcgg tcggactcgc ccatcaccca gagcgcgagg
     1201 gcgagttcac agctctcgcc gccggtcacc caggggttgg gcaggacgca gcgcacgccg
     1261 aggcccggca ccacgaagtc gtcccagccc tcctcgatgc gctccttggc cgcggggccg
     1321 gtgagcgcgc cgccgagcac cgggtagtac cagtccatgg agtagcggct cttgtcgagg
     1381 aaccgctcag ggtgcttgcg gatcgcgtgc gccagcaggc cggtcgccag ctcccagtcc
     1441 ggttgcggct cctcgcggtg ctcggcgatg gcgagggcgc agcgcagcgc ctggtgcatg
     1501 gaggagcagc cggtgaggag cgcgtcggtg acgtccgtgc cgtcctcctc gcgcttccag
     1561 ccgatctggc cgcccggctg ctggagttgg aggacgaatt cgacggcggc gaagacggtc
     1621 ggccacatgc ggtcgaggaa ggcgtcgtcg cctgtggcga ggtagtggtg ccagacgccg
     1681 accgcggcgt aggcgacgaa gttggtctcc cggctgcggt cggtgggttc ggcggcgtcg
     1741 ccgtcggcgt aggcggcgta ccacgagccg tcggggttct ggtggtcggc gagccagcgg
     1801 taggcggcct cggcgcggtc gtgctctcct gcggcgtcca gggccatggc ggcctcgacg
     1861 tggtcccagg ggtcgaggtg gtgcccccgg aaccagggta tggcgccgtc ctcgcgctgc
     1921 acggcggcga tgccggccac cgtgcgggcg gcctggtcgg cggtcaggac gccgggcagt
     1981 acgaggcgct cggtgcggtc cggcctgcgg ccggccctgg tcacgcgcgc tcctcggcgg
     2041 acgcggcggc ggccgtgtcc cggtcctgcg tgcccgcggg cgcgtgcggc ttggtcgcgt
     2101 acgccacgaa gctcttgccg atgacggggt tgaggagctg ctcggcgacc cgggtggcct
     2161 tgggtttctt catgatgtcc cagaccagca gcttgtggta cgcgcggacg ggcagcgcct
     2221 tgtcgttgtc gacgccgaag gcgcacttga gccaccagta ggggctgtgc aggccgtgtg
     2281 cgtggtgggt gccgtacggt gccaggcccg cctcgcgcat cttgtcgagg agttcgtcgc
     2341 cgcggtagat gcggatgtgg ccgccctcga cctcgtggta ggcgtcggag agcgtccagc
     2401 agaccttctc ggggccgtag cggggcacgg tgacggcgat ccggccgccg ggcttgagga
     2461 cccggaccat ctcggcgagc acgcccttgt cgtcggggat gtgctccatg acctcggaga
     2521 tgatgacgac gtcgaagctc tcgtcgggga agggcagggc gagggcgtcg ccctccatgg
     2581 cggtggcggt ggcgcccgcg ggggcctcac cggcctcctt catggccgcg aaccacttgg
     2641 cgacctcgcg tatctcctcg gcgttgcggt cgagggcgac gacctgcgcg ccgcgccggt
     2701 agcactcgaa ggcgtgccgg cccgcgccgc agcccaggtc gaggacgcgg tcgcctgcgg
     2761 cgagcggaaa gcgggagaaa tcgacggtca gcacgaatat ttgctttcgt ccggcggggc
     2821 aggtcgatgg ggcgtggagt gttggcgtga tcaggcccgc cgggggcgga agccccggtg
     2881 cgggaagggc cggggcaggg gggacatcac ccacgccgcc ccgtcggcac ggacgcgccg
     2941 gccgagaggg cgatcgccgc gcggtaccgc tcggccgtcc cgatcgccgc ctgccgccag
     3001 gtgaagcggg acagcacgcg ctcgcggccc gccgctccga gcctgcgccg cagcgcctcg
     3061 tcgccgagca gccggttcag cgcggcggcc agtgcccctg ggtcgcccgg cggcaccgcc
     3121 aggcacgtct cgccgtcggg cccggcgacc tcggggatcg ccccgcccgt cgtggccacc
     3181 agcggcgtgc ccgtggccat cgcctcggcg gccggcaggg agaagccctc gtacagcgag
     3241 gggacgcagg agatctgcgc cgagcgcacc aggtcgacca gttccgcgtc ggtgatgccc
     3301 ttgacgaact cgaccgcgcc ttcgagcccg tgccgcctga tggcgctcgc gaccgggccg
     3361 tcctccgcgc gcttgccgac cacgacgagg tgtgcgccgg ggttctgcgc gcgcacggcg
     3421 gccagcgcct cgacgaggtg gacgaggccc ttgagcggca cgtccgcgct ggaggtggtg
     3481 acgatccggc cggggacctc ggcgacggac gggtccggcg agaagaggtc ggtgtcggcg
     3541 ccgatgggga cgacgtggac ccggcccggg gacaccccga ggtgtgtgac gatctcctgc
     3601 cgcgaggagc cggagacggt cagcacggac ggcagccgcc gcgcgacccg cttctgcata
     3661 cgggtgaagc cgtaccagcg gcgcacggac atgcgccgct tccagtcggc cgcggcggcg
     3721 aggtcgagct gccggtcgac ggtgatgggg tggtggatgg tggtcaccag gggcgccccg
     3781 agcgcggtgg ggccgccgag cagtccgtag ccgagcgtct ggttgtcgtg cacgacgtcg
     3841 aaccgcccgc ggtgcgcggc gaggtgacgg cgggcccgca ggctgaaggt gagcggttcc
     3901 gggaagccgc cggtccacat ggtggcgacc tccagcgcgt cgatccagtc gcggtactcg
     3961 tcgcggccgg gcgtgcggaa ggggtcgggc tggcggtaga ggtcgaggct gggcagctcg
     4021 gtgaggctca cccggccgct gccgacggca ccgtccgcgc cgtcgccgtc gaggacgggg
     4081 tagggctgcg agccgatgac ttcgacgtgg tgaccgaggc gggcgagctc tcgcgagagg
     4141 tggcgtacgt agacgccctg gccgccgcag aacgggttcc ccttataggt gagcagggcg
     4201 atccgcagcg ggccgtcgcc gcccccgtcc acggggtggt cgtcgtgcgc gagcgctgcc
     4261 tccgtggcct cagcggtcac tccgggcctc cttctcgctg ctgtcccgcc ggagcgtaac
     4321 cggtcgcgct aatctagaac aagtttcaga ctgagtcgtc cggaagcctc gaatctaccg
     4381 gccggacggc cagtcgggcg taccggatcg ggtgattcgc gccacggctc gccccctgcc
     4441 atgctgtgcc gtccgagccc cacggacacc gctggatgga ttgccacgga atgggacata
     4501 tgactacgga ctccaggtcg gcaccgaccg ccccttcctc gctgcccaga cccctgctga
     4561 ccgagcgtca ggaggcccgg cggcggcgca tcctccaggc caccacccgg ctggcgaccc
     4621 ggggcggctt cgacgccgtg cagatgcggg aggtcgccga gtcgtccaac gtcgcgctcg
     4681 gcacgctcta ccgctacttc ccctcgaaga tccatctgct ggtcgccacc atgcaggacc
     4741 agctgcaaca gctccacgag acgctgcgca agcgcccctt gaccgacgag gacccggcgg
     4801 cgcgcgtggc ccagacgctg atgcgtgcct tccgcgcgat gcagcgcgag ccgcacctcg
     4861 ccgacgcgat ggtgcgcgcc ctgaccttcg ccgaccggtc ggtgagctcc gaggtcgaca
     4921 ccgtctcccg gctgaccacg gcgatcatcc tggacgcgat gggccccgcg ggcgcgtcgg
     4981 gaccgcccac ccccgagcag ctctcggccg tgcgcgtcat cgagcacacc tggcactcgg
     5041 cgctgatcac ctggctgtcc gggcgggcgt ccatcgccca ggtgaagatc gacatcgaga
     5101 cggtttgccg tctcatcgac ctcaccaacc ccaactctcc ccgctgaccg cccgccctgc
     5161 cccacttcgg cccggatcgc ccgtccccga ctcccggtaa caagaggttc cggggggcgc
     5221 gttcgagtga acttggggcg cgcatggctc gaagtgtgcg cccttgcgcc ccccgcaggt
     5281 cagttatccg cgcccgtgac cgtggcacac gccggtatga atttgacgaa gtacccggcg
     5341 cggcgttcgc cgcccggggt agtgggaggg cggggactga caccgtgatc cgggtcttgc
     5401 tggtgcacga cacccatctg ctgcgcgcgg ccctggcggc gctgatcgcg agagaacccg
     5461 acctggaggt ctcggcgtcc tcctggaccc actcggtggc caagtcgcgc gtgctgctcc
     5521 cccatgtgtg cgtggtggac atggacagcc ccgaagcagg cggaccgtac ggcctgcggg
     5581 agctgtcggc ctggtgtgac gccggggacg gcacatcggc cctgttggcc ctggcgacgg
     5641 cggaacggcc ggggcccctg cgccgggcgt acgaggagcg ggtcttgggg tacttgagca
     5701 aaaacgcttc acctggtcgg ctgatcgagg gaataaggca tgtggcgaag ggcgagcgct
     5761 atatcgacga gtccctcggc tacagcttcc tccaggcctc cgacatcccc ttgaccagac
     5821 gggagttgac cgtgctctcg ctggccgcgg aaggcgcgtc catcggggag atagcccgca
     5881 gcctgcacct gtcgaacggg acggtgcgca actacatggc ggcgatcacc cgcaagaccg
     5941 gcgcccgcaa ccgggtggac gcgatacgca tctcgcgcgt ggcggggtgg gtctgaggag
     6001 ctgcccgggg gccgtctgtc cgtgccgtcc cccgggcccg cttcagggcg tcgaacccag
     6061 cctgtccggc cgcaccaccg ccgtcaggtc gcggtagagc tccgactccc ccagcagttc
     6121 ctcgtgcgtg ccgaggaccg tgcgcgcccc gtccatcacc agcacacggt ccgcgcggcg
     6181 cgccgagccc atgcggtggg cgatgacgat cagcgtgccg tcggtgcggc gcgcgaaggc
     6241 gctctccacc cgggcctccg cctccgcgtc gaggtggcac gtcgcctcgt ccagcaccgc
     6301 gatccgcgcg ggggccagat aggcgcgggc cagggcgatg cgctggcgtt cgcccgcgga
     6361 gagctccgcg ggggtgacgg gggcgccgaa accgcccagc cggtcgacga gttcggtcat
     6421 ggcgaggacg tcggcggcgg cgtggagctc gtggtcgggg acgccgtccg gtcggaggta
     6481 gccgaggttg tcggcgagcg tgccggagaa cacgtacgcc tcctgcggga tcaggacccg
     6541 ccccgcgcgc cccccggcca cgcgcacctc gccgctcccc ggctccagca gccccgcgac
     6601 gagcccggcc agcgtcgact tgccgacccc cgacggcccc acgacggcga gccggccgcc
     6661 gacgggcacg acgaggtcga ggtcgcggag cacgggctcg gcgtgctcgc cgtaggagaa
     6721 ggtgacaccc cgcagctcga cggccgcggg cgaggactcg ggcggtgccc actcgacggc
     6781 gggcggcggc ggcaggggcg gcccgtccgt caggcggcgt atcaccaccg ccagccgcga
     6841 accgctcgcc cccaggccgt ggacgagggc ctgcagggcg ggcaggagcg actgcgtgag
     6901 ataggcgagc gcgccgacga gcgcgcccgg ggtgacaccg cggtccagca gccacggggt
     6961 ggtgaccagc agcaggacga gcgggagccg gcccgcgacg gccagcgcga cgacccgcag
     7021 gacggaccag cgggccaggg cgagggaggc gcggaactcc gcgtcgacga gggcgccggt
     7081 ctgctcccgg acgtacggct ccgccccgcc cgccgtgatg tcccgcaggc cgccggacac
     7141 ctcgcccagg gactgcgcga tggcctcgtc cgtggcgagg aacgtctcct ggcggcgggc
     7201 gagcggccgc agcgtcgcca ggaacagccc gagcccgagc acgaggggcg gcgccacgac
     7261 cacgagcagg acgggcgcca gcaggcacag acccacgagc gcgccggccg ccgtgaagac
     7321 gaaggacctc gacaccatca ccagcccggc gaacgtgtcc cgggcgatct ccacctggtg
     7381 cgtgagccgg gagacggccg cgccgtccgc ctcccgcagg gcgcgcgtca cgacgcggcc
     7441 cacgagccgg tcgcgcagcg gctcgacgag ggcggccacg ccgcggtacg tacggccggt
     7501 gccgaacgcg ccgacgacga cggcgagcgc ggcgagtccc agccaggcga ggccctcgcc
     7561 gggcttgccg gcgaggaagc cgccgtccag ggccttggcg agggcgtatc ccatggcgaa
     7621 ggtgtgcgcg gcttctacgg cggaccaggc ggtgaggcgg gcgattgctc ggcggtgcgc
     7681 ggcgaggaag gtcacgcctc gccggatgag agagggggtg tctgtggtca tccggggctc
     7741 ccttcggggt ggcggctcgg gcaacggcgg cgttctttcc ccagccccgc cccttcccga
     7801 aactgggggc tccgcccccg gacccccggg ggtgcgcaat ccagcccgtc cggcgtttga
     7861 gggcgcggcc gcaggccgct cccgccgcag gcggcaacgg cgggacagcc gggggcctgg
     7921 ggcacgtgcc ccagtttcgg gaaggggcgg ggcggggaac aaaacccgcc gcacccgcag
     7981 ccgctcaccc accgaacacc gcccgatacg ccgcacagcg ccacagcgac tcatgcgtgc
     8041 ccaccgcccg cacgcgaccc ccctccagcc acgcgacagc atccgcgcgg gccgccgtcg
     8101 acgcgcggtg ggcgacgacg agccgggtgc gtgcggcgac gtcgcggacg agggccgtcg
     8161 cgacctcgtg ctccgtgacc gtgtcgaggc tggaggtggc gtcgtccagg atcaggacgc
     8221 gcccggcgtg ggcgaacgcg cgggccaggc ccaggcgttg ggcctcgccg ccggagaggg
     8281 gggcctcggc gcagggggtg gcgtagccgc gcgggagcct gcggacgaag ccgtccgcgc
     8341 acgccgcgcg ggccgcggcc gccaccgcgt cgggcccggg gtcgctcacg ccgaaggcca
     8401 ccgtcccgcc gatcgtgccg cccagcagcg cgggccgttc gaaggcgtag ccgaccgcgc
     8461 gccgcagctc gtcgtggccg agccgcggca gggggacccc gtcgagggtg accacgccgg
     8521 agtccgggtc ggccagccgc ccggcgagcg cggcgaggac ggacttcccg gtgcccgagc
     8581 ggccgacgac ggccagtgac gtaccgcccg gcacgaccag gtccaggtcg cgcaggatgt
     8641 gcctgccgcc gcgcacggcg ccgacccccc gcagctccaa ggtgccgtcc ccgggcggca
     8701 gtcggcggac gtcaggaccg tacggcggga ggggtacgga gaggacgtcg gcgaggcggc
     8761 cggcggcggt gcgggcgcgg accgcggcgt tgaggtggcc cacgagcatg ccgatgcccg
     8821 tggcgagcac ggcgtagcgg gaggcggcca acaggtcgcc gacgctcaac aggccctggt
     8881 tcaggcgcag tccggcgacg gcgaggacgg ctatctgcag gagcggtacg acggtgacgg
     8941 cctgggcggc ggccctgccc tggacccgcc acatgcggtg gccctggccg gagagggcgg
     9001 ggaggggttc caggacgcgg tcccgctcgc ggtcggcggt cccggcggcg gcgatcgtac
     9061 gggccccgcc gacggcttcc accaggcgcc cggcgatgtc cccctggagc cgctggtact
     9121 gggcgacgca gtcggaggag gcgcgggcga gggcccgcag cagcagggcc agcaagggcg
     9181 ccccggcgag gaacgcgacg gcgagccagg ggtcgatcag gccgagggcg acgatgccgc
     9241 cgaggggggc cacgacggag gaggcggccc cggcgagggt gccgggggcg gtgcccgcgt
     9301 cggcggcgtt gccgacgagc cgggtgacga ggtcgccggg cgcgaagcgg gcggtggctc
     9361 ggggcccggc ggcgaggacg tggcacagca ggcggtggcg gagccgggcg gtggcgcggg
     9421 cggtggtggt gccggcgagc agtccgtcga gggcgtcgag ggcggcgggc gcgcagatga
     9481 gggcggtgca caggaggacc cagccgctcg cgccgccgcg ccgggcgagg aggaggtcga
     9541 gggtgtggcc cagggcggcg ggcagggcga gggccacggc ggtggaggcg aggccgagga
     9601 gggtgagggt gagcgcccgt gcggcgctgt ggcgggcggt gtcgagcagc agttggtccc
     9661 cggcggcgcg gggggacgtg cgcgcgtgct tccctcgtgc ctggccgggg cgccgctccc
     9721 gaccccggcc gtcgaggcgc gggccgcgcg cgctctccgt ccacaccacc cgcagtcacc
     9781 tccgcagtac gcccgggcgg gccctccccg tggggagggc ccgcccgagg tctcgtcaca
     9841 gacagagcag gatgctcgcg gtgctgacgc aggagagcag gctgacggtg ctcgcgccgc
     9901 cgccctcgcc gccaccgccg ccgtgcagct cttcggattc catgttctgc aggtcgagaa
     9961 gtgccatggt cgttcctttc atggggacgg gttcttcctg tcacggctcc acaacggcat
    10021 ggagccggct cctgggcgcc cgcgggggcg cgaggaacgg caggcgggcg tcgccgtggg
    10081 ccgcgcccag ggcgagcaga cagcccgctg ttccggtggt gaggtccatg gacaggcgca
    10141 tcatctggct gccggggaag gcgagttcgc cctcgtaggc catggagtac caggacagcg
    10201 cccgcacctg tgcggccagg tgctccgggt cggcgcccgg tgtcgtggtg cggctgaggt
    10261 gcaggatcat cccggcgcgg ccctggaaga ggccgggctg cgcgtagaag cgggaccggg
    10321 cggcggtgag gatgccctcg cgcgcctcgg cgaaggaggg gtcggggtcc gggcacaggg
    10381 cgaggtagtc gtcgagcacc atgccgatgc ccacgctgcc gtcgccgagg tagggcatgg
    10441 tccgccagcc ctcgtcgact tcgagggcgc cgttctcgcg ccgtacgcat cggtcgaggt
    10501 ccgcgcgcag ggccgttcct gcgaggtcga ggagggcggg ggcgcgcgtg cgctcgtaca
    10561 gccgcaggaa gagcagcgcc tggcccgcgc cgccgcgggt gagcccggcg cgccggcggg
    10621 tgcggtcccc gggcgcggcg gcgtcggcag ccagccggtc ggcgaggagc tgtgccgcct
    10681 ccaacgcccg gtcgtggagc tgccgttcgc ccgtggtgcg ggcgaggtgg tcgagggcga
    10741 ggccgatccc ggccaggccg ctcttgaggt cggaggtgag gcgctgccac ttctcgccga
    10801 gcacggtcgt ggtcaggtcg agggcgcggc cggtgtggcc gaggcggtcg agggtgaggg
    10861 cgaccccggc gatgccgtcg tagaggccga gcggggtgcc gggcggcagc gggtcggtgt
    10921 ggtcgagcag ccaccgctcg ccctcttcgt agcgctcggc gcccgtctcg gcgaaggcgt
    10981 gcagcacccc ggcggcgccg tgcgccagcc cgaggccgcc gccgtcggtg aactgggcga
    11041 cgtcgccggg gaagagccgg tcgtcgcggt cgggcgtagc ggaggcgagg atcgcgcgga
    11101 ccatcgagtc ccggctgcgc ggccagtcgc ccgcctcggg cagcacgggc gcgtcgtcgg
    11161 cccggcccgc gcggggcgcc atgccggcct gcttgccggg cacttcggca acaggcgcgt
    11221 cgcgggtgat ctcggcgacc gcctcgtcga ggaactcccg cggcacgggg aactgttccg
    11281 cgatcacctc ggccaggtgc gcggccttcc cccggtcgat gacgaacagc atcgtgacgg
    11341 gcaggaacag cgcgagccgc aggcaggcca gggcgtagcg gtccacgtcg gcgcccctgc
    11401 ggtccggcgg cgcgaagaag ccggggtggg cgacgacctg ccggccgtgc tcggcggcgg
    11461 gggcggcggc ctcgaagtcg atgagggcga cggagcgttc gtcgggcgcg accatgatgt
    11521 tgaacatgtg caggtcgttg aagaccaggc ccctcgcgtg caccgcgtcg accgcttcct
    11581 ggaccgcgcg gtggatgcgc agcgcccagg ccgtgtagtc ggccgtggcg gcggggtcgg
    11641 gctgcgcggc gagcagcggg tgccgttcgg agaagaagga gttgagggtg cggccctcga
    11701 tgtggtccat gacgaggaag ctgtggtccc cgagcgtgaa ccagtcgcgc acctcggggg
    11761 cgacgccgag gccggtcagc cgctccagcg ccgccttctc gcgctccagc cgggccacgg
    11821 cgtcggcacc gtcggaggcg agcccggcgt gcggacggcc ctccttgagg acgaccttgc
    11881 ggccgtcgcg ggtgtcggtg cccgcgtaga cgccgccgcc gttggagaag tgcagggcct
    11941 tctcgatgcg gtacgggatg tcgccgacgg tggtggcgtt gcgggccgcg aggtggggtt
    12001 cgaggaaggc ggggagggtg acccacgcgg gcacctggaa cgcgggcgtc cgcgggtcgg
    12061 gcacgagctg cccctcgccg ttctcgacgg cgggcacgag cgtgccgcgc tcgtcgacgc
    12121 agaagcgccg ggcgaaggcg ccgtagcgga cgtagagcgg gccctcgtgc cagcgcaggt
    12181 cggtgaggac gtacgggccg ggcctgccgc cgacgatccc gtgcagctcg gtgagcgtgg
    12241 tgcgcagctg ctcctcgtcg gcggggtaga cggtgatgaa cttcccgctg tggtcgcgcc
    12301 cggcgtattt ggtgttgcgc aggtgcagca ggtgcgggcc cggcacgaac ttgaagggga
    12361 tgccgcgttc gacgcagtag tcccagacgt cggcggcggt cttgtccgcg gtgtccgcgg
    12421 tggcggacac atggatcttc cagccctgga gcggctgtcc ggggcggggc ccgccggtgt
    12481 cgtcgagcgg caggaggtgg agccagtcgc cgctgcgggc ggtgtcccag ccggccggga
    12541 ccgggcgccg cgcggtctcg aacagcgcgc ccggacccgt cccctcggcg ccctccccgg
    12601 ctgcggacag gcggtccggg gtctcgtaga agtgcctgtc ggccaggcag tagacctcgt
    12661 accgcttgtc catcgattcc ccctcggctg cgatgcgtcg agatttccac ggcccgaggg
    12721 gacggaacag tcacagctgt catgaacagg cagtgcgata cgcacgcgta accgggggcg
    12781 gacggtccgt ccgagagcgc acggggtcta cccgggcgct cctacgggcg caggctcata
    12841 cggccatctc tttgtgggcg atctccgcgc agtgccggtc ccacgccgtg cggtacgagg
    12901 cggcgtgggc ggggtagccg agttcgtcgg cctgctcgac ggtggcctgg taccgggagc
    12961 acagaccgca ctcctcccgg gtcggccagg agggcgggcc gccggtgtgg ggcacgggcg
    13021 gtgcgtccac caggccgtgg aagggcggga gttcaaccat gggggcactc tctccctgga
    13081 ccctcgcgag gcgcagcagg cggcgcccca gccggatgag cgccctcacg gcgcgtcggt
    13141 ctcggccggg ctggcgtcgc cctcttcttc ggtacgagcc tccggcggct cctcgacgag
    13201 ggggtgctgg gacttgagcc gctgctgaag cgtcgggcgg gacagcggtg gggctacggc
    13261 ggtgccgggg aaacagggca tggggcggct ccgtatctga gcggggcggg tgggcgcggc
    13321 ggtcgccgca cacggaaacg gccgggcgag cgcttacgcg aagcgcccca cctcgactca
    13381 ggcagcatgc cggtaagcgc gaggggcgcg caatattggg gtgccaatag acaaagaaag
    13441 aaagcctgtt ctatcgactt gcaaacccac ttcgcggcac actgcacccg gatgacgcgt
    13501 tgcagccccc aactctcctg cgagtgcacc cagttgcccc accatgagac cccatgaggg
    13561 ctgccaagca cccagcagtc aaccggaagg cgaaacagaa gaatgccgac agtgccgctg
    13621 gtccccaccc ttcgtcgccg gcgtctcggt gaggccctcc gccgcttccg caacgaagcc
    13681 ggtctcacca tcgaacaagc tgccgccctc atggggtggg acaacagcaa gctctccaga
    13741 atcgagaacg ccaaggtcca catccgcccg gtcgaggccg cgaagctcct cggcacctac
    13801 ggcgtggacg cgccggacat cctcatggcg atcgagatac tggccaaaga cgcgggaaag
    13861 aagggctggt ggacgaccta cggcagcgtg gttgacgcgc acatcaagga ctacctgtca
    13921 ctggaatcgg atgccgagag cacccgcatc tgttccatgg gcctgatccc tggcctgctg
    13981 cagacaggcg gctatgcacg agagatcatc gccgcctcat cattctggcg gccccaggaa
    14041 gaagtaactg ccctcgctga agtccgcaaa gcgcgtcagt ccgtactcac cacccgcgac
    14101 ggcaggccac cgctgaattt ctgggctgtc atccatgagt cggtactgca ccaacggttc
    14161 gcgtcccggc cgaccatcat gcgtgatcag ttgcgacacc tgctggacat ggccgaactg
    14221 ccgaacatca ccatccagct cctgcccatg gccatggcac cgcaccccgg gatggtcggc
    14281 ctgttcgagg tcgtccgctt ccctgctccg tggccaacag tcatcctcac ggaaaatttg
    14341 gtgggcgggc agttcgtgga gggcaccgaa cacgtgggcc tcttcgagaa ggcgtttgag
    14401 cgcatcgttg ccgccgcact tcccgtggat gattcgcgcg agatcatcaa gaacatcatg
    14461 gagaagggtt aggaatggac cacaaggaag acctctacgg actcgacctg tgcggagcca
    14521 cttggcgcaa gtcgcccgac agcaacggtg gccagtcatg cgtcgagatc accgatctcc
    14581 ccgacggcgg catggccgta cgcgactcga agaaccccga acgccccgac ctgcgctaca
    14641 ccgcagacga gtgggccgcc ttccgctcag gaataatcaa cggcactttg tagtcgtcga
    14701 tctgagcaat gatctgactg aggggcctcc ccggacgcat cggggaggcc cctcgccatg
    14761 aacttcccag gggggggaca agtgcgacgt tccatcattc ttgccggtgc cgtggtctta
    14821 ctgtgctcgg cgtgttccgg ttccggtgcc gcgtcgaagg agacgaagcg gcccgcagcc
    14881 ggcgcggcgg gtgttcacga cgccgcagtg caggccgcag tgggtgcgac gacgaagagc
    14941 agcgcccgga tcgacgagca ggtcgaatgg accgacggca cccgcggcta cacagtgatc
    15001 gtcaagggcg gcttcgacct tgcgagcggc aaagggcgtc tgacagcgaa aattccgggc
    15061 cagtcgacca tcgggcctta cgacgagatc ttcaccaggg acaccgttta tctcagaatg
    15121 cctctggaga tcaacgacga tcccgcttgg tggtcggtct cccgggacaa ggtcgagacc
    15181 cacaacgtcc ttcgcgcgcc agtgaacgac cccgagcacg tcctgcgcca ggtggcacgg
    15241 atgcgcgaga cttcgaaggt cggcgaggag caggtggacg gcgcgccgac cgtgcgctac
    15301 cgcggcaagc tggacaacga gacgctcaca ctccggctga ccgaggacag acgcgaggag
    15361 atctctatcg cccggaaggg gctgggcagc gaccttcccg cctccgcgga tgtctggatc
    15421 gaccggagcg ggcgcgtcgc ccgcatccgt ttcgagctca tcatggggac aggcagtgtc
    15481 acgaccacga tgtacctgac ggaccacggg aagcccgtgg aggcaccggt cgccccggga
    15541 ggtgccaagc ctctgcccct ggccgcgctc ggcggccctc tcacaggctg aacctcacat
    15601 atcgccatgc tcctccagcg ggaacaccgc ttgccccacg accgggcatc atcccttcct
    15661 gacgagaacg ccttccatgg agctcgtaac acgatcttgt tgatcgtgtt acgagctcat
    15721 agctgcgttt cgaggctccg acgaacaacc cgatcgccac ggaggttttg ccctgtctcc
    15781 ctacgtcggt ccatcggacg gcagcacagg gcgggctcag ttgacgaact ccatgctctg
    15841 gaagtcggct ccacgagtcg tctcatggcg cctgagcgca tacgaggagc ccacacagcc
    15901 tgcacgcggg tacagcagga cgtccctatt cgtgaggttg gccgtgtacc cctggcctgc
    15961 tatgtcgtag cagtggttgt cactcggatc gtacttgctt ttctgtttgc cgggaacggt
    16021 gtactcgaag tcgcccctgg cccggtggtg gaaccgcagg cttttgaaag ccacttcccg
    16081 gtgatcccgt ggcgccatgt gctgcggtat gccggagcag ttgttctcgt cgaacagctc
    16141 cactacctgg tcggtctcgt tcctcgccag gccgtcggcc cccaggtagg gatagcaggt
    16201 tgcctccggg tccggcagca cccgcggctc ggacggctcg gtgtagatga attcaccttg
    16261 cgcggccacg gcgtcgggtg tagcccctgt tacgagcccc acccccaggg cagcggcaac
    16321 tgcgaggacg ccgaaccgta gcctcaactg acgaattcca cgctcttgaa cttcatccac
    16381 ccctgcttgt ccctgtcgag gtggtgcttt gcctccccat ggcaatccgc acggtcatac
    16441 agcagagcca atttgtcggt gctgttcacc gtgtgaccgt ccccgacgat gttgaaacag
    16501 tggtcgttcc tggggttcga caagctgtcc gtgtcgcctt taggggtggt atatacgaac
    16561 gttccctcgg ccgcttgcgc gcttccggct agcccaacag ccagcacggc ggcggcgccg
    16621 accgcagcgg cagccatgac caagcgcttc atactgtccc tctcccaagc tgaagtccca
    16681 tgtatggcac gagagttcac ctctcctcgc gccgccccag acactgccag gacagccagc
    16741 cgccccggaa gcagaagttc ggccatcccc ccggcaggcc gagaacgcaa ccttggccac
    16801 agacgggccc tcgtcgcggc ttccgggtgg gccagtgaca ggctctactt cttgagcagt
    16861 tcgcgccatt tatcgttctt ttgatactcc gcagcctttt tctggtactc aataaaatcg
    16921 gcagtgagac cacccccgcc actcgcctcg acttcgccga ggcgaggcca aggactgtcc
    16981 atgaatttat aaccaaacgc cctgaggcca gccagctcgc gtccgaaaac cctgagcctc
    17041 ccctcggcga agtcgaaaac gttggcctcc gtccgcggcg aagccaggaa gaactcctgt
    17101 gcgtcatgca cacctgcgag cagccaggaa tcgttcacca acaccgacca tcgcttcgaa
    17161 tcgagcacac agcccatttg cgcgaactgc tttgtcgttt catccatcgt tccaaagttc
    17221 ttcttcactt tcggatcaat gccagccccc tgctgctctg ggtcttcctc ggtgcgcaag
    17281 ccccctatga ccagccctaa aaattgcggg ccgagatcct ttcgcgcctt caataccgcg
    17341 ctgtagacgc accaggcgac gccgaccctt tctgcgctga aggcgtcgtg cccgtcccag
    17401 gatttaccga gccccgcttc cttgtagatc ttctcggccg ccttcgccgc ctttacgaac
    17461 tcatccttgc tcttgaacat tttccgctcc tctgcgcaga caatggactc aattccacgg
    17521 aagcagctct tcgttacgct tagaaggcag catccagaca tcgcacacaa ggccggaaag
    17581 cccatcttgc gtcccggagt gtcggggccc ccttcccagc ggacggccag gcgcttgaac
    17641 tggtgcagca gcgcgaaggt ctgctcgaca tcgaaccgga gctttcccag gcccccgatg
    17701 ttcgggggcc tttgcgggag atgaccggca ggatgcgccg cttgcacagt tcccagcggt
    17761 tggggttgct gtcgtacccc ttgtctccca gcagggcagc ggggcgtctg cacgggcgtc
    17821 cgggccgtcc ggcgacagcc gggatgccat caacgagggc gagggtccgt gtgacgtcgt
    17881 tgacgttggc cgcggtggtg atgaccttga gcggggcgcc cttcccgtcg cagatcagat
    17941 ggtgcttact gcccgtcttc cggcggtcga cgggctgggg cggaatgatg tcgaccgcgg
    18001 tgacggagtc ccgctgctgg ttgacgacga tggccaggga cctctggtgc cgacgtgtcc
    18061 tgaccatgta gccctgccct ccgacgaccg aacaccggct gactaccacc acactcccga
    18121 cctgccgggt cactgagcaa ctgtcagcac ctgccgggac cgtaggtcgg cagcggtgcg
    18181 cgcgcagcgc gagcggctcc aaaaggggga actcactcct ccggcgggaa gaccactccc
    18241 tccgcgctcc ggatcgtgat cgcctccacc gggcacgact ccgccgcctc cagcaccgct
    18301 tcggacgcgg gcgtctcctc ctccaccggg tgggagcggc gcgcctcgtc caggtggaag
    18361 gcgcccggcg ccgtcgccgc gcacaggccc gagccgacgc atacggcgcg gtccaccgtc
    18421 acccgccagc gctcggcgtc ggcgggcatc agccctcgta ccccgcgggc aggtggatca
    18481 tcttgtgttc ctggtaggcg gcgaagccct cggggccgaa ctcgcggccc aggccggagt
    18541 tcttgtagcc gccgaagggg ccgagcatgt cgaggctgaa ggtgttcacg gagtaggtgc
    18601 cggtccgcac gcgccgggcg acggcgatgc cgcgttcgac gtcggaggtc cagacgctgc
    18661 cggagaggcc gtagtcggag tcgtcggcga tgcgcacggc ctcctcctcg tcctcgtagg
    18721 gcagcaggca gatgaccggg ccgaagatct cctcgcgggc gatccgcatg gtgttggtga
    18781 cctcgccgaa gagggtgggc tcgacgtacc agccgtggcc gggcgcggcc gggcggccgc
    18841 cgccggcgag gaccttggcg ccctcgcgct gtccgagcgc gatgtagtcc agggagcggc
    18901 gtcgctgccg ctcggcgacc agggggccga cctgggtggc ggggtcgagg gggtcgccga
    18961 cgacgagggc gtcggccgcc gcggcgaagc gcccggccag ctcgtcgtag tggacgcggg
    19021 ggacgaggat gcgggtctgg gcgacgcacg cctgcccgtt gttcatccag gcgctgggca
    19081 cgatgcccgc gacggcggcc tccagatcgg cgtcggggag gatgatcgcg gcggatttgc
    19141 cgccgagttc gagggtgacg cgggtgaggt tgcgggcggc gacctccatg acgcgcttgc
    19201 cggaggcgac cgagccggtg aaggacacct tgtcgacgcc ggggtgcccg acgaggtact
    19261 cgccgacctc gcgcccggcg ggcaggacgg acaggacgcc ctccggcagc ccggcctccg
    19321 cggcgatctc ggccaggatg taggcgtcca ggggggtttc gggcgccggc ttgagcaccg
    19381 cggaacagcc cgtgagcagc gcgggcgcga gcttggcggc ggccacgaac tgcgggacgt
    19441 tccacggggc gacggccgcg accacgccga cgggctcgcg ccgtacgagc agcggcccga
    19501 ggaccccggc gcgccgctcc tcgtacggga tgtccctcgc gacgccgatc gcgcagtccc
    19561 acaccatcat cgcgccgagg gcctgcgcga ggacgctcca ggagcagggg gagccgttct
    19621 gcgcggagat gacccgggcg atctcctcgt ggcgggcggc gatgccgtcc ttgatgcggg
    19681 tgacgacgtc gagccgctcg gccagcggtg tctgtgccca gacgccggag tcgaaggagg
    19741 tgcgggcggc ggcgaccgcc cggtcgacgt cctcgcggga ggcgtggggc acgcgtccga
    19801 tgacggtctc ggtgtgcggc gagacgacgt cgatggtgtc cgtccctgcc gggtcggccc
    19861 aggtgccgcc gatgaagagc tttccgtgct cgatgaattg cgccatgtcc ggtcgcctcc
    19921 cgcgtggccg ccgagcccgg cggctcttct gacgctacgt cagaactgtt accagttctc
    19981 gttatagtgg gcaatggccg acgcccgtcg gcgacggggg gagccatgcc tcaggtgacc
    20041 gaccacggcg gcggggtggt gtccatcccc gtccccatcc cggacaaccc cctcggccac
    20101 accctcgtcc acctcctgga caccgaccgc ggcccggtcc tggtcgacac gggctgggac
    20161 gaccccgcct cctgggacac cctcgtcgcg gggctcggcg cgtgcggcac gtccgtcacc
    20221 gagctgcacg gcgtcctcgt cacccaccac caccccgacc accacggcct gtccgcccgg
    20281 gtccgcgagg tctccggcgc ctggatcgcg atgcaccccg ccgacgcgga cctggtccgc
    20341 cgcctgcgcg cggccccgcc cgggcagtgg ctcgaccagc tcgtggcgaa gctcgtcgcc
    20401 gccggggcgc ccgaggagca cctggccccc gtcgaggcgg cccgcgcccg gggccgcgcc
    20461 cgcccgctgc cgggcagccg ggccgcgctg cccgaccgcg agatcgcgcc cggcgagctc
    20521 ctcgacctgc ccggccgcag gctgcgcgcc atctggaccc ccggccacac ccccggccac
    20581 gtctgcctcc acctggagga ggcccacccg ctcggccgcg cgggccgcgg ccggctcttc
    20641 tccggcgacc atctgctgcc gggcgtcacc ccgcacatcg ggctgtacga gttccccggc
    20701 ggccccaccg ccaccgaccc gctcggcgac tacctcgcct ccctcgaacg tgtcgccctc
    20761 ctcggcccgg ccgaggtgct ccccgcccac cagtacgcct tcaccgacgc ccccgggcgc
    20821 gtcgccacgc tcctcgccca ccaccgggcc cggctcgcgt cgctgcgcgc gctcctcgcc
    20881 accccgcgca cgctctggca gctcaccgag tcgatggagt ggaaccgccc ctggtcgcgc
    20941 atcccctacg gctcccgcaa catcgccgtc gccgaggccg aggcccacct gcgccacctg
    21001 gtggccctcg gccacgcgga ggccgtgccg ggcggcccgc cggtgaccta cgtcgccgtg
    21061 tgaccggggc gtgcgggggt acgggccgcg gccggaccgg cggctaaagt gtccgtgaca
    21121 acttcatccc gcctcggaac ggggaaagcc ggtgcgaatc cggcgctgac ccgcaaccgt
    21181 gaagtacggc cccgccccgg cgcggccgta cgagccggac cacccgggcc caggcggcag
    21241 gctcccggat ccggtcgcgc cgaccacggc acggcccggt ccaccggcac cgtcgaggta
    21301 tacggagccg agcccggtgc caccgcgcgg tgacaggcgc ggaggggctg ccgtgcgcgg
    21361 ctgtgaccgc ccgtaccacc ccgtatcccg gcgtcgccgg accaccgcag tgacacccac
    21421 cgagaggcac cgaccccatg gccccctcct tcgccgtcca cgcgcgccgc ggcgccgcgg
    21481 ccctggccac cgccgccgta ctcggcgcgg gcctggcacc ggcagcgtcc gccgcctccc
    21541 cgtccccggc ggcccccggc ctgttcggcg cctcggaccc gaagttcgac ggtgtcttcc
    21601 ggcagtccct ggccctcctc gcccagcaca cggcgggcgt cgcgtcgccc gagccggccg
    21661 tcggctggct ggccgggcag cagtgcgcgg acggcggctt caccgcctac cgcgccgaca
    21721 ccggcaaggc gtgcgacgcg aagaccccgc tcgacagcaa cgcgacggcc gccgccgtcc
    21781 aggcgctcgc cgcgctcggc gggcacggcc ccgccgtgac caaggccgtg gggtggctga
    21841 agtccacgca gaacgaggac ggcggctggg gctacagccc cggcggcccg agcgacgcca
    21901 actccacgtc gatcgtgatc ggcgcgctgg cggccgcggg cgaggacccc gcgaaggtca
    21961 cctccaagag gggcacgtcg gcctacgacg gtctcgtcgc cttccagctg ggctgcgacg
    22021 tcgacgaggc ggaccggggc gcgttcgcct accagcccga caagtccggc aagctcgccg
    22081 ccaacgccga cgccacggcc gcggtcgccc tcgccgggct cggcaagggc tacgcggcac
    22141 agcccgcggg caaggacaac gtggacgcga agccgctgcc ctgcaagggc gacgaggccg
    22201 ggacgtccga cccgaaggcc gccgcgggtg ccgcgtccgc gtacctcgcg cggatcatgg
    22261 acaaggagaa ggacggcccg cacctggccg ccgtccagcc cggcgccgac aagcccgccc
    22321 ccgacttcgg caacaccgcc gagaccgtca tcgccctcgc cgcgggcggt caccgcgacg
    22381 ccgccgcgaa gccgctgaag tggctgcagc agaactccgc cgcctgggcc aagcaggcgg
    22441 gccccgccgc gtacgcccag ctcgtactcg ccgcccacgc ggcgggcgcg gacccgcgcg
    22501 acttcggcgg cgcggacctg gtgtcccagc tcggcgcgac gggcccgaag gcggaggccg
    22561 cggcttcccc gtcggagaag aaggacgaga agcaggaaga gaagaaggcg aaggacaaca
    22621 aggggctggg cgtctggtgg gtcgtcggcg tcttcttcgt cgcgagcgtc ggc
//
