LOCUS       NZ_CP031455            22028 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces olivoreticuli subsp. olivoreticuli strain ATCC 31159
            chromosome, complete genome.
ACCESSION   NZ_CP031455
VERSION     NZ_CP031455.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces olivoreticuli subsp. olivoreticuli
  ORGANISM  Streptomyces olivoreticuli subsp. olivoreticuli
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Complete genome sequence of Streptomyces olivoreticuli ATCC 31159,
            producer of anticancer bestatin and diverse secondary metabolites
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8809793)
  AUTHORS   Zhang,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-AUG-2018) Tianjin Key Laboratory of Food
            Biotechnology, College of Biotechnology and Food Science, Tianjin
            University of Commerce, NO.409 Guangrong Road, Tianjin, Tianjin
            300134, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 29-JUN-2018
            Assembly Method                   :: SMRT Link v. 5.1.0
            Assembly Name                     :: TJCU_BT_311
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Reference-guided Assembly         :: SMRT Link v5.1.0
            Genome Coverage                   :: 145.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003391135.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 04:49:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,562
            CDSs (total)                      :: 7,459
            Genes (coding)                    :: 7,276
            CDSs (with protein)               :: 7,276
            Genes (RNA)                       :: 103
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 7, 7 (5S, 16S, 23S)
            tRNAs                             :: 79
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 183
            CDSs (without protein)            :: 183
            Pseudo Genes (ambiguous residues) :: 0 of 183
            Pseudo Genes (frameshifted)       :: 61 of 183
            Pseudo Genes (incomplete)         :: 150 of 183
            Pseudo Genes (internal stop)      :: 18 of 183
            Pseudo Genes (multiple problems)  :: 41 of 183
            CRISPR Arrays                     :: 5
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:12:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 541079
            Orig. end                         :: 563107
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031455.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Hongyu Zhang.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22028
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="4"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22028
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22028
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12028](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12028)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(156..3887)
                     /locus_tag="DXZ73_RS02485"
     CDS             complement(156..3887)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS02485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162889979.1"
                     /transl_table=11
                     /translation="MSLVALVTAALLGAAAPATLAAPPSAPRPVAGLPAAGQTIAGHEV
                     IKVRGMGGVELRAVRIPIPGSEVASSIAVAVDRHSLEGHAMPYEKEAGGAEKAEAFVRR
                     IEENLEKLAAFPKGKDLLKGISRMRPLDVATGKAGPATGRTDINTIFFRGLPGDRKAWP
                     DDIRKDFEKRSQKQQLEDGFAFVMDGPMAVPIDTETDRKSDGNGSESMIGMPDDPIVVI
                     GRQPDTSRFALDESLAVGHELIHAAHNLQGADATLPDAGKLPVEVPYKDPSGKSRTETA
                     YIDAEEVSTLGGKDRKRYLTSVTSESGKGRFGYKHMNNSWKLLKEAEEAAKKTSAADRK
                     ALLKEVRKGREKTFDITETDLAKERGVPARQHYALPYEFENDWGKQLGKIEDLFTVPPG
                     LAVTDKDLKNPDRLMERLQQAETAALHSCSPGRRSMICRPSGRPEDVSEETKQRIEEAG
                     RVLEEQPDTPVWLPWEEDAAAERQQARSEAEAAGKQLEKRLGERAKELCAASGEAACLG
                     KVDWEKARKELRADAEELVEKKLLAVENVKDIKLDKDFAAALGDASGFYLPYDKTREAV
                     SGHTGEGGDHTGINASKLADKAGKAMWLAGIAQAFVADSSNLDKAAAVTAMMPAVGNLM
                     QLSADAVKQDWTHLGFDAAFVLLEGAEFLGLEAAGPAGWAVMGIELIVDQFINFAKKEA
                     EKGAMLDTMAKQAHDGALRAVSDTSSKGWMAHGGSTTVLQMALAMMQTVEVQRASVKGV
                     ARAIGAADSSSTVPDGTDLRKETWAADKQFADADAKADALATQSLAEIRKAVARRLADQ
                     LNKLWDDEKTQKKFVEPYASRYAELEYGDGYTGEYSRGSKVLACAGRDSSWPNETLCGI
                     WNFKPKPVDAAEVEEILKAMGLPGTAAPQRDTVLAGLLTAQGASGQVDAVMPVPGADRE
                     YWAFSGGQYVRMRLDDKADGRKLAATLTGKGGPAPVKSNWRSLEALLAVSKTGRIDAAM
                     PVPGADRDLYVFSGDQYTRIRLDGDLKDTAVGGYDKPRSLPEKWSSLEDLFAKSGAQRV
                     DAVQAVPGNNTEYYVFSGSWYTTIRLDDNLKDWQMVGSRRISSGWPMLVGESGQDQVQG
                     LMPVPGTDRDFYVFTNGGYARANAKTLRLQTPNAAASAWVMSKQAQIFWSNGADLPADA
                     KLIAREQGSDEEHSYPARDGKSDYWTAPTVNLWESGKQRVIDVHYRYTHPDGTVEWSPS
                     STVKFECSPAVCKGIPQH"
     gene            4235..4435
                     /locus_tag="DXZ73_RS02490"
     CDS             4235..4435
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS02490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116209401.1"
                     /transl_table=11
                     /translation="MRRTSAGSHLQRADQLLSPAHDRLVADHRRYSADNGMWAMTALNG
                     FQELVVQARDDALVTYTDSPQ"
     gene            4432..4635
                     /locus_tag="DXZ73_RS02495"
     CDS             4432..4635
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS02495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_116209402.1"
                     /transl_table=11
                     /translation="MTNAPKPTTQARALDAYLAVTDLADGLDSTLAALQSVRAAPDTLA
                     RTCRALSRAVVFLAKKLKAPCK"
     gene            complement(4673..5368)
                     /locus_tag="DXZ73_RS02500"
     CDS             complement(4673..5368)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012275.4"
                     /locus_tag="DXZ73_RS02500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hemopexin repeat-containing protein"
                     /protein_id="WP_162889980.1"
                     /transl_table=11
                     /translation="MVKKVYTITRPLHVEAGTWHYVKWHWISEDVAHKEIDQGFADVFQ
                     GTPEQRRWFAAAVASGRSIPSLYVAKTGKVYFLHGDTYVRCTQETLTVDEGFPKSIGSY
                     WPGLKAVGFDSGIDSILSWDEKTVYLFKGLQYVRYNLETNKVDDGYPKTIAVYWPGFKE
                     AGFDSGIDAFVRWDTDRAYAFKDDQYIRFHIPTNRTDQAPRKTISYWNPLASLGPSRLM
                     AMYLTGEVG"
     misc_feature    complement(5345..5360)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.0"
                     /tool="antismash"
     misc_feature    5602..5615
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.8"
                     /tool="antismash"
     gene            5642..6097
                     /locus_tag="DXZ73_RS02505"
     CDS             5642..6097
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DXZ73_RS02505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_162889981.1"
                     /transl_table=11
                     /translation="MNKEFAKEPRDTAVATGTPMLGREHYEITVSNQSTHALVLTSKAV
                     SGAFDEAPDEGHVLRPRESDTFRVTSVHFLGESGFPWESSTAVVRYQMADTPVTFTATG
                     GPPGSHVSSGTLEGPGCEHYDCTIGSSCNGNTLVMLETATDPYMMGM"
     gene            complement(6229..7062)
                     /locus_tag="DXZ73_RS02510"
     CDS             complement(6229..7062)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016574917.1"
                     /locus_tag="DXZ73_RS02510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PIG-L family deacetylase"
                     /protein_id="WP_116209405.1"
                     /sec_met_domain="PIG-L (E-value: 2.3e-27, bitscore: 95.0,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDRPLTLMAVHAHPDDEATGTGGILARYAAEGIRTVLVTCTDGG
                     CGDGPGGVKPGDPGHDPAAVALMRRQELKASCDVLKVGDLEMLDYADSGMTGWPSNDTP
                     GSFWRTPVEEGAARLAQLMRHYRPDVVVTYDENGFYGHPDHIQAHRITMAALEMTALTP
                     KVYWTTMPRSMMQRFGEAMREFHEDMPEPDPAEAAAMAEIGLPDDEITTWVDTTAFSGQ
                     KFDALAAHASQGESIFFLKMGKERFGELMGTETFLRVQDTTGAAVPENDLFAGLR"
     misc_feature    complement(7217..7231)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.36"
                     /tool="antismash"
     gene            complement(7307..>7499)
                     /locus_tag="DXZ73_RS02515"
                     /pseudo=""
     CDS             complement(7307..>7499)
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009189552.1"
                     /locus_tag="DXZ73_RS02515"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="DnaB-like helicase C-terminal domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="SEQQCGGSAGRDAMGLLHREDAYEKGSPRAGEADLLVTKHRNGPT
                     SHHDRRFSKPLQPFRGHGI"
     misc_feature    7516..7531
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.3"
                     /tool="antismash"
     misc_feature    7574..7592
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.37"
                     /tool="antismash"
     gene            8297..8881
                     /locus_tag="DXZ73_RS39110"
     CDS             8297..8881
                     /GO_function="GO:0004144 - diacylglycerol O-acyltransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018657.4"
                     /locus_tag="DXZ73_RS39110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WS/DGAT domain-containing protein"
                     /protein_id="WP_240351098.1"
                     /transl_table=11
                     /translation="MAAAAGALRSCFGDPAGRSLRHTRSRGQVFTYIPVSLRTADTMDE
                     LGNITSTVRVPLPLHTDTPAARLMACRGLVDAFGPRALAVPELLARLVSLLGPRAMDAV
                     LARAGGPPFVAVGCTALPWGRAQLTLGGHPLSRVVAFPVVQPAGGCAFVLSGYADTSAI
                     AVTTHRLPGDARDLADAFAHEIDLLAALGAA"
     gene            8881..9984
                     /locus_tag="DXZ73_RS02525"
     CDS             8881..9984
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025072.4"
                     /locus_tag="DXZ73_RS02525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_116209407.1"
                     /transl_table=11
                     /translation="MATDAAEGPPRVLVISGSMGAGHDGAARGLIHQLRERAVGADFRD
                     FLDALPRSYRQLLRAEHAFTIRHTPRVFDWMARSEERDSVVRRLTLRICRVARREVARW
                     AAGGYGVVVTTFPLASQTLGMLRRDGALGVRAVCCLSDPAPTRLWLHPGIDLYLTVTQA
                     TVVEAAERYGVAMAVGGPLVAAAFREPVDKAAREALRTELGVPPGRRMVLLTGGALGIG
                     NVMAGIAAVRQVPGTVAVVLCGRNDRLRRRAAAQRGVIALGWRDDVPRLMATADVLVHN
                     AGGLSMTEALVAGLPAVSYEMLGGHGRENAATLARAGLAPWPRTPAELAEALERQASRG
                     RVFLPPVPAGQETASVVEALARQGCTG"
     misc_feature    9475..9477
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10001..12028)
                     /locus_tag="DXZ73_RS02530"
     CDS             complement(10001..12028)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01787.1"
                     /locus_tag="DXZ73_RS02530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_162889983.1"
                     /sec_met_domain="T2TS (E-value: 2.1e-96, bitscore: 322.3,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPATHTPDETPAPHPVVSPALAHRKALDRLLSLQHEAGCWEGEMV
                     WNTMILSQYVIVCRIVGRTLPEPTRAAMTRHYGSTVTPEGGWGLHAESGPSPYCTVLAH
                     IALRLLGNRADDPLCADSAAWLRSQPGGARAVPTWGKLWLAVAGLHDYRAINPLPPELF
                     LLPRRLPVHPDRLYCHTRSIYQAMAYLYGIRFSGDLGHPLTDELRRDLLGESRPGARPP
                     CRSDRRLLGADAQVPPGRALRAAFDVLAVYERHPLRRTRARALARCLARVTHEQEVTRE
                     FGLSPVSSLLNVLVLHASGAAPTAVDRALTAVDHWRWTDQERGIRYAGARSQTWDTAFA
                     VEALLAHGPTDTGDPTDAAVLTALRRGCGFLRDAQVTDEVPHPEVTARAPAAGGWCFSD
                     GAHRWPVSDCTAEAAATLLHARHLLPETTVPDEGRLRQATAFLLHRQNRDGGFGSYEPR
                     RGSRLLEAANPSEMFSDCMVEGSYTECTGSALVAFTALARPEDPEHREEMDRAIRHGAH
                     FLLRRQCKDGSWPAAWGVNRIYGTLFAVRGLRATGMPPTHPRLARAARWLESVQRADGG
                     WGEHHQGCTENRYVEHPDSQPVMTAWALLALLDITGPGSASVRDGVRWLCERQADDGSW
                     HQKAVTGVFFGTAMLDYRFYAEYFPLWALGAHLAALGRAG"
     gene            complement(11946..13088)
                     /locus_tag="DXZ73_RS02535"
     CDS             complement(11946..13088)
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039236.3"
                     /locus_tag="DXZ73_RS02535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="WP_116209409.1"
                     /transl_table=11
                     /translation="MTGPPGFGQARGRRQKVLATGMDPDYWYPVEYDRGLHPGKALATS
                     FWGHPIVVWRGRDGLLRALEDRCAHRQLRLSAGVVNGCHLTCEYHGWTYGGDGRVVHYA
                     HDLFGRAEPEVKVRDYPVASRHGIIWVFPGDPARATERDVPGIPELTGPRPWPRMDISY
                     VWHAHHSMIMDNTNDFTHAYLHRRYRPFWDARLTHHGMTEDGEGVEISYDAFIGGGRFV
                     RHLVDRSRADTTSIDLAYRYPYQCSDTGGFIKHWLFLLPMDRRTTRVFFIFYFNAGGIR
                     IPGINRTAPYRLTGPLMRAVSALTARPTLSQDGAAVEEEQRGYERHFATTTVELNPAVR
                     LCQDLTVRKWEEHLARDAHARRDPGSPPGRQPGTGAPQGP"
     gene            complement(13085..14137)
                     /locus_tag="DXZ73_RS02540"
     CDS             complement(13085..14137)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (3-169). E-value: 3.3e-14.
                     Score: 44.5. Matches aSDomain:
                     nrpspksdomains_DXZ73_RS02540_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF027681.4"
                     /locus_tag="DXZ73_RS02540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_162889984.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.7e-08,
                     bitscore: 30.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.2e-08, bitscore:
                     30.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.1e-12, bitscore:
                     44.5, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILVTGATGHLGANLVRGLLAEGREVRVLVRGEAGPALDGLAVHR
                     VPGDLRDPEAVGRAVTGCEEVYHCAAQVSTANGGKREIYEVNVLGSHHVLAAAWRADVR
                     RVVVTGSLSATGWRRGVPSTEEDLFYPFGQHTPYTVSKVLMEHECAKAAARGLDVVVAT
                     STAIIGPHDYLPSRMGRLLLDFANGRLLAYVPGGFEFVSATDVVAGHLLAMRHGSAGRK
                     YLLSTQYHTVDEMLDLYGEVCDRPRPRLRVPPAVMSGVARAVAPALSLLVPHHEPRLTP
                     AAVGFLRSQRRADCSRAVSELGYRPTSVARAVEQAYACFARRGLIGRRRAVVPPPLRAR
                     LPRRRPTGPS"
     aSDomain        complement(13631..14128)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXZ73_RS02540_NAD_binding_4.1"
                     /evalue="3.30E-14"
                     /label="DXZ73_RS02540_NAD_binding_4.1"
                     /locus_tag="DXZ73_RS02540"
                     /protein_end="169"
                     /protein_start="3"
                     /score="44.5"
                     /tool="antismash"
                     /translation="VTGATGHLGANLVRGLLAEGREVRVLVRGEAGPALDGLAVHRVPG
                     DLRDPEAVGRAVTGCEEVYHCAAQVSTANGGKREIYEVNVLGSHHVLAAAWRADVRRVV
                     VTGSLSATGWRRGVPSTEEDLFYPFGQHTPYTVSKVLMEHECAKAAARGLDVVVATSTA
                     IIG"
     CDS_motif       complement(14069..14131)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DXZ73_RS02540_0001"
                     /evalue="5.30E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="DXZ73_RS02540"
                     /protein_end="23"
                     /protein_start="2"
                     /score="9.5"
                     /tool="antismash"
                     /translation="LVTGATGHLGANLVRGLLAEG"
     gene            14272..15594
                     /locus_tag="DXZ73_RS02545"
     CDS             14272..15594
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1161: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="DXZ73_RS02545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_116209411.1"
                     /transl_table=11
                     /translation="MQTVDVLVAGAGPAGCMTALAFARQGATVLVVEPGTEPTRRLAGE
                     WLHPAGVTALRRMGITPADREFTTNHGFQLHTGDGNPPLHCPYPDGVALSMYHHVLSTL
                     LLRTVRADPGITLRQGDRVTAVATAGRAHTTCEEIRAGLIVGADGRASTVRRLLRPGEP
                     APAPLSHTAGLLLHGVRLPRGGYGHVFLGGPGPVLAYQVAPDTVRLCLDVPVPRPTPSE
                     IRGYLLHGYTTALPAELRPAFADVLTGGKIQWAAARFRRRSFYGRGRCALVGDAVGHGH
                     PLAALGMSLALLDSECLARRSPDIHAYATERTARSWAAERLGAALHRTLTGADPASLLL
                     RRAALDLWRRDPGQRGLVLGLLGMRDERRSAFCDVVAHVTANALTDLARAEPTLPGTTA
                     SVRHLVGLADWLLWLAGPAVGTPRPPRALRGRLRGLTVMGP"
     gene            complement(<15609..>15704)
                     /locus_tag="DXZ73_RS40000"
                     /pseudo=""
     CDS             complement(<15609..15704)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268836.1"
                     /locus_tag="DXZ73_RS40000"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MVRECEGRNAKPSPCVLDSQIIKISANVPLSG"
     gene            16084..16416
                     /locus_tag="DXZ73_RS02555"
     CDS             16084..16416
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942575.1"
                     /locus_tag="DXZ73_RS02555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_240351100.1"
                     /transl_table=11
                     /translation="MADFYGAYIDAVSDGTDDLAEHLRAHYLTEDLRQRLAAWEETNHA
                     DGVLRAQDVPTGWEVRYHDSGAGHLFTTVTLTWGTGPGAGHSQLAVQSDLATKLISDIE
                     NNPSES"
     gene            16660..17118
                     /locus_tag="DXZ73_RS02560"
     CDS             16660..17118
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /GO_process="GO:0008150 - biological_process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328266.1"
                     /locus_tag="DXZ73_RS02560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR03618 family F420-dependent PPOX class
                     oxidoreductase"
                     /protein_id="WP_116209413.1"
                     /transl_table=11
                     /translation="MTQGPAPRPLSDEALSGLLGKQQFGTLATVKRSGHPHLTTMLYNW
                     DPEARILRFSTTADRIKVGHLRRDPRATLHVQGGDVWSFAVAEGEAEVSEITTVPGDGV
                     GRELLEMIPQAAKPDDERAFLEQLVAERRVVIRLKVSRLYGTALDIDG"
     misc_feature    complement(17149..17160)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            17172..18050
                     /locus_tag="DXZ73_RS02565"
                     /pseudo=""
     CDS             17172..18050
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946701.1"
                     /locus_tag="DXZ73_RS02565"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGQGGAGDLSDREWARLEPYLPRKVGRGGRWKSHRGVINGILFRQ
                     RTGVPWRGPPARFGIWKAVHDRHRRWSADGAWERVLRAVQADADAEGRIDWSMGPRAVP
                     ISTPRAPAPARRVPLDNAASLFSIVRTRPRAAPVAGSPARSTSPVRAADVRPRPSSHQA
                     SGATPRN"
     gene            18219..19355
                     /locus_tag="DXZ73_RS02570"
     CDS             18219..19355
                     /NRPS_PKS="Domain: Aminotran_1_2 (25-364). E-value:
                     7.4e-52. Score: 168.6. Matches aSDomain:
                     nrpspksdomains_DXZ73_RS02570_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="DXZ73_RS02570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_116209414.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1e-49, bitscore:
                     168.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERISQAAARLGRLPVRISGGVPTQDVVSLDRGDPDFSTPAPIVD
                     AMDRALRDGYTHYGDLNGDPELRAYIAERASAYTGDRYDDSQVLITPGSTAGLATAIYA
                     IAGPGDRIVLFDPTYPAYAEQAALAGATVVRVPFREDGGLHLEALQESVVGARLLVLCH
                     PSNPTGAVFSEADLRGLAAVLEGSDTIVLADEAHADIVYDHRPYISTMGIPELRPRLVN
                     CRSFSKTYAMAGWRLGYLIAPPELAKVIRRIHLIYNCGVNSAVQRAGLFALRTGTSLVM
                     PMLQEYQHRRDLVVDWMRQTGLLRGRVPEGTFYAYPHYPHPIGSVEMVRHLLRYGVCVR
                     AGAFDGPGGEHHLRISFSTNTTDLIEGLSRLEKGLRAL"
     aSDomain        18294..19310
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DXZ73_RS02570_Aminotran_1_2.1"
                     /evalue="7.40E-52"
                     /label="DXZ73_RS02570_Aminotran_1_2.1"
                     /locus_tag="DXZ73_RS02570"
                     /protein_end="364"
                     /protein_start="25"
                     /score="168.6"
                     /tool="antismash"
                     /translation="DVVSLDRGDPDFSTPAPIVDAMDRALRDGYTHYGDLNGDPELRAY
                     IAERASAYTGDRYDDSQVLITPGSTAGLATAIYAIAGPGDRIVLFDPTYPAYAEQAALA
                     GATVVRVPFREDGGLHLEALQESVVGARLLVLCHPSNPTGAVFSEADLRGLAAVLEGSD
                     TIVLADEAHADIVYDHRPYISTMGIPELRPRLVNCRSFSKTYAMAGWRLGYLIAPPELA
                     KVIRRIHLIYNCGVNSAVQRAGLFALRTGTSLVMPMLQEYQHRRDLVVDWMRQTGLLRG
                     RVPEGTFYAYPHYPHPIGSVEMVRHLLRYGVCVRAGAFDGPGGEHHLRISFSTNTTDL"
     gene            19352..20380
                     /locus_tag="DXZ73_RS02575"
     CDS             19352..20380
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012885.4"
                     /locus_tag="DXZ73_RS02575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_116209415.1"
                     /sec_met_domain="HMGL-like (E-value: 7e-35, bitscore:
                     119.6, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPKWTSRVPTLLDCTLREGPYECRFGSEEMAIIAKQLQQSGITH
                     IEVGAETGLGTNPQVDDIDQIRTVAAAAPGTRVGVIAGASSTTVDDLRRVVDAGAGFIR
                     VAAAVTDSTTALPLIEAVADWNVPVTFNAIKCYAVEQQQLLSIAKDVTAAGAHVFYLVD
                     SAGSMLPRTVHRRTAALHDLGIQVGFHGHDNLALAVANSLAALDAGAIAADGTLRGIGR
                     SAGNAQLEVLVKAAQQHGSLTEVDGDALCRLSEELIAERRLRDRGVSFLDIAMGEGRFH
                     SERLDLAREVAHAYQVPLESLVRATGQSDPVAPDRNLLEQTAALLRADPPAEAAHSWPG
                     HW"
     gene            20392..21243
                     /locus_tag="DXZ73_RS02580"
     CDS             20392..21243
                     /GO_process="GO:0018193 - peptidyl-amino acid modification
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354931.1"
                     /locus_tag="DXZ73_RS02580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartyl/asparaginyl beta-hydroxylase
                     domain-containing protein"
                     /protein_id="WP_116209416.1"
                     /transl_table=11
                     /translation="MGKTSNRVKAIEGQVARIGRLGAQPTEAVAQEVMTLPQPQDWVLD
                     SGEHQSGGWWTCSLLNASGDPRDVTLQDCDPAPTTLLERMPATRTLLESLGLHYMWARL
                     ARLEAKSFLWEHRDYGNLSEAERHRLHIPLHTNPSAYLVTRGAKVHMYAGHMWRLTPTH
                     QHGVCNLDGPDRIHLLLDCYADDAYRSRAATAELLDGDVEQLPDITADQLAEAKITARR
                     LAEGGDISGAENRLLRLFYLYALPEGRIYDLVMDLHRTLGREQDVRRWREHKRLALKQD
                     AA"
     misc_feature    complement(21508..21522)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
ORIGIN
        1 cgccagccgg aacggtggcg ggccggcccg gagcaacgaa ggtcctgtcc cggtccgtcg
       61 ggaccgggac aggaccttgt tcaccactgc cgggttcact cagggatggc cgggctcagg
      121 acagggcaag cgcggtacac ccggccgggt ggggatcagt gttgggggat gcccttgcac
      181 acggcgggcg agcactcgaa tttgaccgtc gagctggggg accactcaac ggttccgtcc
      241 gggtgcgtgt accggtagtg gacgtcaatg acccgttgct tgccggactc ccagagattc
      301 accgtcggcg ccgtccagta gtcgctcttg ccatcccgcg ccgggtagga gtgttcctcg
      361 tcgctgcctt gttcccgggc tatcagtttc gcgtccgcgg ggaggtctgc gccgttgctc
      421 cagaagatct gagcctgctt cgacatcacc catgcgctgg ccgcggcgtt gggagtctgc
      481 agtctgaggg tcttggcgtt ggccctggcg tagccgccat tggtgaacac gtagaagtcc
      541 cggtcggtgc cggggaccgg catcaggccc tggacctggt cctgtccgga ttcgccgacg
      601 agcatgggcc atccgctgga gatccgccgg gagcccacca tctgccagtc cttgaggttg
      661 tcgtcgaggc ggatcgtcgt gtaccaggag ccggagaaca cgtaatactc ggtgttgttg
      721 cccggaacag cctgcacggc atccacccgc tgggctccgg acttggcgaa caggtcctcc
      781 agcgaagacc atttctccgg caggctccgc ggcttgtcgt acccgcccac cgcggtgtcc
      841 ttgaggtcgc cgtcgaggcg aatacgggtg tactggtcgc cggagaagac gtataggtcc
      901 cggtcggcac cgggaacggg catggccgca tcgatcctgc cggtcttcga cacggcaagc
      961 agcgcctcca gtgaccgcca gttgctcttg accggagcgg gtccgccctt gccggtgagt
     1021 gtcgcggcga gcttcctgcc gtcggccttg tcgtccaggc gcattctcac gtactgcccg
     1081 ccggagaacg cccagtactc ccggtccgct ccggggacgg gcatgacggc gtccacctgt
     1141 cccgaggctc cctgtgcggt gagaaggccg gcgagtacgg tgtcccgctg cggtgccgcg
     1201 gtgccgggca ggcccattgc cttgaggatt tcctcgacct cggcggcgtc gaccggcttc
     1261 ggcttgaagt tccagatgcc gcagagcgtc tcgttgggcc aggaagagtc gcgacccgcg
     1321 caggcgagga ccttgctgcc gcggctgtat tcgccggtgt acccgtctcc gtactcgagc
     1381 tcggcgtacc tcgacgcgta aggctccacg aatttcttct gggtcttctc atcgtcccag
     1441 agcttgttca gctggtccgc aagacggcgg gccaccgcct tgcggatctc ggcgagagac
     1501 tgcgtggcaa gagcgtcggc cttggcatcg gcatcggcga actgcttgtc cgcggcccag
     1561 gtctccttgc ggaggtccgt gccgtcgggg acggtcgagg aagagtcggc ggcgccgatg
     1621 gcacgggcca cgcccttgac gctggcccgc tggacctcga ccgtctgcat catggcgagg
     1681 gccatctgga ggaccgtcgt ggaaccgccg tgggccatcc atcccttact gctggtgtcc
     1741 gagacggcgc gcagggcgcc gtcatgcgcc tgcttggcca tggtgtccag catcgcgccc
     1801 ttctcggcct ccttcttggc gaagttgatg aactggtcca cgatgagctc gatccccatc
     1861 acggcccatc cggcggggcc ggccgcttcc aggcccagga actcggcacc ttccagcagc
     1921 acgaaggccg cgtcgaagcc gaggtgggtc cagtcctgct tgaccgcatc ggcggacagc
     1981 tgcatcaggt tgcccaccgc gggcatcatc gcggtgacgg cagcagcctt gtccaggttg
     2041 ctgctgtcgg ccacgaacgc ctgggcgatg ccggcgagcc acatcgcctt gcccgccttg
     2101 tccgccagct tcgaggcgtt gatgcccgtg tggtcgccgc cttctccggt gtgcccggag
     2161 accgcctcgc gtgttttgtc atacggcaga tagaagccgg acgcatcccc cagcgccgcc
     2221 gcgaagtcct tgtcgagctt gatgtccttg acgttctcca ccgccaggag cttcttctcc
     2281 accagctcct cggcgtccgc acgcagctcc ttgcgggcct tctcccagtc caccttcccc
     2341 aggcacgccg cctcaccgga cgccgcgcac agctccttcg cccgctcccc gagacgcttc
     2401 tccagctgct tgcccgcagc ctccgcctcg gaacgcgcct gctgccgctc cgcggcggcg
     2461 tcctcctccc agggcagcca gaccggtgtg tccggctgct cctccagcac ccggccggcc
     2521 tcctcgatcc gttgcttcgt ctcctccgac acatcctcag gccgaccgct ggggcggcat
     2581 atcatcgagc gcctgcccgg cgagcaggag tgcagggcgg ccgtttccgc ctgctggagc
     2641 ctttccatga gacggtctgg attcttgaga tccttgtcgg tgacagccag gcccggcgga
     2701 actgtgaaca ggtcctcaat cttccccagc tgcttgcccc agtcgttctc gaactcatag
     2761 gggagcgcat agtgttgtcg ggccggcaca ccacgctcct tggccaggtc ggtttcggtg
     2821 atgtcgaatg tcttctcgcg ccccttccgc acttccttca gcagggcctt ccgatccgct
     2881 gctgaagtct tcttagctgc ctcctcggcc tccttgagga gcttccatga gttgttcatg
     2941 tgcttgtatc cgaaccggcc cttgccggat tcggatgtca cgctggtgag atagcgtttg
     3001 cggtctttcc cgcccagtgt cgatacctct tcggcgtcga tataggcggt ttcggtcctg
     3061 gacttgccgc tgggatcctt gtacggcacc tccaccggga gttttccagc gtccggcaag
     3121 gtggcatccg cgccctgcag gttgtgggcg gcgtggatca gctcgtgccc gaccgcgaga
     3181 gattcatcaa gagcgaatcg gcttgtgtcc ggctggcggc caatcaccac aatggggtcg
     3241 tccggcatcc cgatcatgct ctcggagccg ttcccgtcgc ttttgcggtc cgtttccgta
     3301 tcgataggta ccgccatagg gccgtccatg acaaacgcga agccgtcttc aagctgctgc
     3361 ttctgggagc gcttctcgaa atccttcctg atgtcatccg gccaggcctt ccggtcccca
     3421 ggaaggcctc ggaagaatat agtgttgata tccgtgcgtc ccgttgccgg gcccgctttt
     3481 ccggtcgcta cgtccagtgg gcgcatccgg ctgatgccct tcagcaaatc ctttcccttg
     3541 gggaaggcgg cgagcttttc gaggttttcc tcgatccgcc tgacgaacgc ctcggccttc
     3601 tccgccccgc cggcttcctt ctcgtagggc atcgcatgcc cctcgaggct gtgccggtcc
     3661 acggcgaccg cgatactgga cgccacctcc gagccgggaa tcggtatgcg gaccgctctg
     3721 agctccaccc ctcccatccc tctgaccttg atgacttcat ggcccgcaat ggtctggcct
     3781 gcagccggca ggccggctac gggccggggc gcggaaggtg gtgcggccag cgttgcgggg
     3841 gcggcggctc ccagaagggc ggctgtgacg agcgccacca gtgacactcg cgtcgatctc
     3901 ttaaaaaccg ttctcatcta tttctctcgg atccgtcaca ccgacagcca atgccacctg
     3961 cctctccaga acaggaggcg gcatcacccg cgtgacggga atactcatga ggggatgcga
     4021 gaccgcgaaa agggcggaaa ggctgccagg gaagcccggg cagcaacccg cacacgggga
     4081 caccaacgcg caggtgccgg ccgcaccggc cggcacctgc actgcactcc cgcgtccatt
     4141 atcgctaggt caagcgttag taaaggtgac tttaacatcg aaaggcatgg tttagccgac
     4201 aacaatttcg cccgcgaatt cctgaaatgg gtccttgcgg agaacgtcgg ccggctccca
     4261 cctacagcgc gccgaccagc tgctcagccc tgcccatgac cgcctggtag ccgaccaccg
     4321 ccgatacagc gcggacaacg gcatgtgggc gatgaccgcc ctcaacggct tccaggagct
     4381 tgtcgtgcag gcccgcgacg acgcgctggt cacctacacg gactcgccgc aatgaccaac
     4441 gcaccgaaac ccacgacgca agcccgcgcc ctcgacgcct acctggccgt caccgacctg
     4501 gcggacgggc tcgacagcac gctcgccgcg ctccagagcg tccgagccgc cccggacact
     4561 ctcgcccgta catgccgggc gctgagccgg gccgttgtct tcctcgccaa gaaactcaaa
     4621 gcgccgtgca agtgaatgga cgggcgcgca caccaggggg cgcgggaccg tctcacccaa
     4681 cctcgcccgt caggtacatg gccatgagac ggctcggacc caggctggcg agcgggttcc
     4741 agtagctgat cgtcttcctg ggtgcctggt cggtcctgtt ggtggggatg tggaagcgga
     4801 tgtactggtc gtccttgaag gcgtaggccc ggtcggtgtc ccagcggacg aaggcgtcga
     4861 tgccgctgtc gaagcccgct tccttgaacc ccggccagta gacggcgatc gttttggggt
     4921 agccgtcgtc gaccttgttg gtttcgaggt tgtagcgcac gtactggagg cccttgaaga
     4981 ggtagaccgt cttctcgtcc cacgacagga tcgagtcgat cccgctgtcg aagcccacgg
     5041 ccttcagccc cggccagtac gaaccgatcg acttcgggaa gccctcatcg acggtcagcg
     5101 tctcctgcgt gcaccgcaca tacgtgtcgc cgtgcaggaa gtagaccttc cccgtcttcg
     5161 ccacgtagag cgaaggaatg ctccgccccg aggccacagc cgccgcaaac cagcgccgct
     5221 gctccggcgt gccctggaaa acatctgcga agccctgatc gatctccttg tgggcgacgt
     5281 cttccgaaat ccagtgccac ttcacgtagt gccaggtgcc tgcctccacg tggagtggtc
     5341 gggtgatggt gtagaccttc ttcaccatgg cggacctcct gccgctgtcg aaggcattgc
     5401 gtggccagcc tcgcgatccc gggactgctg tcgcgcaggc catgcctccg acagcgtcac
     5461 gtacccccag gccggcggca ccccggatac agagcagtac gcccatacgg atgaccttcg
     5521 acccggagtt ccccaggccg gaagcgggca ctcacccact gatcagggga ccggtgctcc
     5581 cccgctcatc ccgacggtcg ggtgaccctg cgtgcacgct cccgcgcgca cgctggaggt
     5641 catgaacaag gaattcgcca aggagcccag ggatacagcc gtcgcgaccg gaactcccat
     5701 gctggggcgt gagcactatg agatcaccgt gagcaaccag tcgacgcatg cgctggtact
     5761 gacgtcaaag gccgtgtccg gggcgttcga cgaagccccg gacgaaggac acgtcctccg
     5821 tccccgggaa tcggacacct tccgggtcac ctcggtccac ttcctcgggg agtccggctt
     5881 cccctgggag tccagcacag ccgtagtccg ctaccagatg gccgacaccc ccgtcacctt
     5941 caccgcgacg ggcggcccgc cgggcagcca tgtgtccagc ggcacgctgg aagggccggg
     6001 ctgcgagcac tacgactgca ccatcggcag cagctgcaac ggaaataccc tcgtcatgct
     6061 ggaaacagct acggatccct acatgatggg catgtgaacg acttgtgttc cgccgccatc
     6121 aatcggcggc ggaattgcag ggtctcgcgg ctactgtcga agaccgtcct cgtggcctgc
     6181 ggcttctccc ccagcctcac ggcgtcgggc cccaggcgga cgggcgggtc agcgcagtcc
     6241 ggcgaagagg tcgttctcgg gtacggccgc gccggtggtg tcctggacac gtaggaaggt
     6301 ctccgtgccc atcagctcgc cgaacctctc cttgcccatc ttgaggaaga agatgctctc
     6361 gccctggctg gcgtgcgcgg ccagcgcgtc gaacttctga ccgctgaatg cggtggtgtc
     6421 cacccacgtg gtgatctcgt cgtcggggag gccgatctcg gccatcgcgg cggcctcggc
     6481 aggatccggc tccggcatgt cctcatgaaa ctcgcgcatg gcctcaccga accgctgcat
     6541 catcgagcgg ggcatcgtcg tccagtacac cttcggtgtc agcgcggtca tctccagcgc
     6601 cgccatcgtg atgcggtggg cctggatgtg gtcggggtgg ccgtagaaac cattctcgtc
     6661 gtaagtgacg accacatcgg gccggtagtg ccgcatgagt tgcgcgagtc gggcggcgcc
     6721 ttcctccacg ggggtccgcc agaaggatcc gggggtgtcg ttgctcggcc agcccgtcat
     6781 cccggagtcg gcatagtcca gcatctccag atcgccgacc ttcaggacgt cacagctcgc
     6841 cttgagttct tgacggcgca tcaaggcgac ggccgccgga tcgtgcccgg gatcgcccgg
     6901 cttgacaccc cccggtccgt caccgcaacc gccgtcggta cacgtcacga gaaccgtgcg
     6961 gatgccttcc gccgcgtacc gcgcgaggat ccctccggta ccggtggcct cgtcgtcggg
     7021 gtgggcgtgc actgccatga gcgtcaaggg ccggtcagtc atgaaacagt cctcctgcag
     7081 aaatcgtctc ggtccgggag cgcggcgggc gtaccgcgat ccccgggccc ggatcctgcc
     7141 agggcggacg accttacggt ctccgtgtcc cccgcccgtg cggcgccggt cccttcgtcg
     7201 atgcaacagc tgcggccgga ccggctgttc ccgccacggc cgcccgacct tccagacgtc
     7261 ggcgtttcca tccgaacgag gtacacaggt acgacctgca cgtcgtctat gccatgtcca
     7321 cgaaacggct gtagtggctt tgaaaagcga cggtcatggt ggctggtggg gccgttgcgg
     7381 tgtttggtca cgaggaggtc cgcctcgccc gcgcgagggg agcccttctc gtaggcgtcc
     7441 tcgcggtgca gaaggcccat cgcatctcta ccagcagaac cgccacactg ctgctcagaa
     7501 caatcaggat gttgcaacta caaaggtaag cggcatctgt tgcacgatcc agcaggaacc
     7561 taacagtttc ggcttattgt atccggtagt cgacgtttcg cgggcccgcc gcttaggcag
     7621 tatcaggtcg atgagcagtt ccttccccct ctcggtgaca gatgagttcg tggcccggcg
     7681 gacccgtgtg ccacccgtcg ggtgcgtgac tctcctcctc tctggcagcc cgcccgtctt
     7741 ggacgacctt cggcaccgtg tgtcggcgag gtggggccat ctggcgcgcc ttcggtgggt
     7801 gctcataccg ccccctgcgg cgtcccgtgg aggccggcac cactgggcgg tgcagaccgc
     7861 cttctccgcg gaacatcatg tcgtccagga tccgccccaa cccaccctcg aggcctgggc
     7921 gtccgacctt ttgctgcgcc cgctgccatc ggaccggcca ccgtggcagc tccacctcat
     7981 gccctctccg gcggaggggg gatactggct cctgctgcgc ttgcatcacg cccttctcga
     8041 tggggaatca gcggtcgcac tgatacgtct gctcctcgac ggaccgtcgc ccgcggtcgc
     8101 gaagtcccgc cgacgcccca accgcagtaa cccgcgccgc gttctggaga gccacctggg
     8161 gtccgggctg gccattccgc tgcctaccgg ccaccgtgcc cagccgggcc atgcctggtc
     8221 accgatcgac gccgacaggt tccgggcggc acgccaggcc ctgcccgggc acacggcgac
     8281 caccacggaa acggtgatgg cggccgcagc cggcgcactg cgctcctgct tcggcgaccc
     8341 ggccggacgg tccttgaggc atacccggag ccggggccag gtcttcacct atatcccggt
     8401 gagcctccgc accgccgaca ccatggatga actgggcaac atcacgagta ccgtccgcgt
     8461 acccctccct ctccataccg acacacccgc ggcacgcctc atggcgtgcc gcggtctcgt
     8521 ggacgccttc ggcccccgcg cgctggcggt gcccgagctg ctcgcccggc tcgtgtcact
     8581 tctggggcca cgagccatgg acgccgtcct cgcccgtgcc gggggacccc cattcgtggc
     8641 cgtcggctgc acggccttgc cctgggggcg tgctcagctc actctcggcg ggcatcccct
     8701 gtcccgggtc gtcgcgttcc ccgtcgtaca gcccgccgga ggctgcgcct tcgtcctcag
     8761 cggctatgcc gacacttccg ccatcgccgt cactacccac cgtctccccg gtgacgcccg
     8821 cgacctggcg gacgccttcg cccacgaaat cgacctcctc gccgcactcg gcgccgcctg
     8881 atggcgacgg acgcagccga agggccgccg cgcgtgctgg tgatctcggg cagtatggga
     8941 gcgggtcacg acggtgccgc gagagggctc atccaccagc tgcgggaacg cgcagtggga
     9001 gccgacttcc gtgattttct cgacgcgttg ccgcgctcgt accggcaact gctgagagcc
     9061 gagcatgcgt tcaccatccg ccacaccccc agggtgttcg actggatggc ccgcagtgag
     9121 gagcgcgact cggtcgtccg caggctgacg cttcgcatat gccgagtggc tcgtcgcgag
     9181 gtggcacggt gggcggcggg gggatacggc gtcgtcgtca ccacctttcc cctcgcgtcg
     9241 cagaccctgg gcatgctccg gcgggacggt gctctgggcg tgcgcgcggt ctgctgtctg
     9301 agcgacccgg cgccgacccg gctgtggttg caccccggca tcgatctgta cctgacggtt
     9361 actcaggcca ctgtggtgga ggccgcagag cgttacgggg tcgcgatggc ggtcggcggg
     9421 ccactggtgg ccgccgcgtt ccgtgaaccg gtggacaagg ccgcccgcga agcgttacgc
     9481 accgaactgg gtgtgccgcc gggtcgacgg atggtgctgc tgacgggcgg tgcgctgggg
     9541 atcggcaacg tgatggcggg catcgcggca gtacggcagg tgcccggcac cgtcgcggtc
     9601 gtcctgtgcg gtcgcaacga ccgtctgcgg cggagggccg cggcccagcg gggcgtgatc
     9661 gcgctcggct ggcgcgacga cgtgccgcgc ctgatggcca cggccgatgt cctggtccac
     9721 aacgcggggg gcctgtcgat gaccgaggca ctggtcgcag ggctgcctgc ggtcagttac
     9781 gagatgctgg ggggccatgg cagggagaac gccgccaccc tcgcccgcgc cgggctcgcc
     9841 ccttggcccc gcacccccgc ggagctggcc gaggccctcg aacgccaggc gtcgcggggc
     9901 cgggtcttcc tgccgccggt gcccgcgggg caggagacgg cgagtgtggt cgaggcactg
     9961 gcgcgacagg ggtgtacggg gtgaaggggc cgcatcgccg tcagccggcc cggccgaggg
    10021 ctgcgaggtg ggcaccgagc gcccagaggg ggaagtactc ggcgtagaag cggtagtcga
    10081 gcatggcggt gccgaagaac acgccggtca ccgccttctg gtgccaggag ccgtcgtcgg
    10141 cctggcgctc gcacagccag cggacgccgt cgcgcacgga cgccgatccg ggaccggtga
    10201 tgtccagcag cgcgagcagc gcccaggcgg tcatcacggg ctggctgtcc ggatgttcga
    10261 cgtagcgatt ctcggtgcag ccctggtggt gttcgcccca gccgccgtcg gcgcgctgca
    10321 cggactccag ccagcgtgcg gcccgggcca gccggggatg cgtcggtggc attccggtgg
    10381 cgcgcagtcc ccggacggcg aagagggttc cgtagatacg gttcactccc catgcggcgg
    10441 gccaggagcc gtccttgcac tgcctccgaa gcaggaagtg ggcgccgtgc cgaatggccc
    10501 ggtccatctc ctcgcggtgc tccgggtctt ccggtcgcgc gagcgcggtg aaggcgacga
    10561 gtgcggagcc ggtgcattcg gtgtaggagc cctccaccat gcagtcggag aacatctcgg
    10621 aggggttcgc cgcctccagc aagcggctgc cccggcgtgg ttcgtacgat ccgaatccgc
    10681 cgtcccggtt ctgccggtgc agcaggaacg ccgtcgcctg ccgcagccgc ccctcgtcgg
    10741 ggacggttgt ttccggcagg aggtgacggg cgtgcaggag cgtggctgcc gcctcggccg
    10801 tgcagtcgct gaccggccag cggtgggcgc cgtccgagaa gcaccagcct ccggcggccg
    10861 gggcgcgggc ggtgacctcg gggtgcggga cctcgtcggt gacttgggcg tcgcgcagaa
    10921 atccgcagcc tcggcggaga gcggtgagta cggccgcgtc ggtggggtca ccggtgtcgg
    10981 tgggcccgtg ggcgagcagg gcttcgacgg cgaacgcggt gtcccaggtc tgcgaccggg
    11041 cacccgcgta gcggatgccg cgctcctggt ctgtccagcg ccagtggtcg acggccgtca
    11101 gggcccggtc cacggcggtc ggggccgccc cggaggcgtg cagcaccagg acgttcaaca
    11161 gcgaacttac cggggagagg ccgaactcgc gcgtcacctc ctgctcatgg gtaacgcgtg
    11221 caaggcatcg ggcgagcgcg cgggcgcgcg tccggcgcag ggggtgacgc tcgtacaccg
    11281 ccagcacgtc gaacgcggca cgcagcgcac ggcccggtgg cacctgggcg tcggcgccga
    11341 gcagccgacg gtccgagcgg cacggcgggc gcgctcccgg ccggctctcc cccagcaggt
    11401 cccggcgcaa ttcgtcggtg agcgggtggc cgaggtcccc ggagaagcgg atcccgtaga
    11461 ggtaggccat ggcctggtag atggagcggg tgtggcagta gagccggtcg gggtggacag
    11521 ggagacggcg aggcagcagg aagagttccg gggggagcgg attgatggcc cggtagtcgt
    11581 ggagccctgc gacggccagc cagagcttgc cccaggtggg caccgcccgc gctccgcccg
    11641 gctgcgagcg caaccaggcc gccgagtcgg cgcacagcgg atcgtcggcg cggttgccga
    11701 gcagccggag cgcgatgtgg gcgaggaccg tgcaatacgg ggacgggccg gactccgcgt
    11761 gcaggcccca gccgccctcg ggggtgaccg tggagccgta gtgccgcgtc atcgccgcac
    11821 gggtcggctc cggcagggtc cgcccgacga tgcggcacac gatgacgtac tgggaaagga
    11881 tcatggtgtt ccacaccatc tcgccctccc agcaacccgc ctcgtgctgg agtgacagca
    11941 gccggtcaag ggccttgcgg tgcgccagtg ccgggctgac gaccgggtgg ggagccgggg
    12001 tctcgtcggg cgtgtgcgtc gcgggcaagg tgctcctccc acttgcggac ggtgagatcc
    12061 tggcagagcc ggacggccgg gttgagttcc acggtggtgg tcgcgaagtg ccgctcgtac
    12121 ccccgctgtt cttcctccac ggccgcgccg tcctgggaca gcgtcgggcg ggcggtgagt
    12181 gcgctgaccg cgcgcatgag ggggcccgtc agccggtaag gggcggtccg gttgatgccg
    12241 gggatccgga tcccgccggc gttgaagtag aagatgaaga agacccgtgt ggtgcggcgg
    12301 tccatgggca gcaggaaaag ccagtgcttg atgaagccgc cggtgtccga gcattggtag
    12361 gggtagcggt aggcgaggtc gatggaggtg gtgtcggccc ggctgcggtc cacgaggtgc
    12421 cggacgaagc ggccgcctcc gatgaaggcg tcgtaggaga tttccacgcc ctccccgtcc
    12481 tccgtcatac cgtggtgggt cagcctggcg tcccagaagg gacggtaacg gcgatgcagg
    12541 taggcgtggg tgaagtcgtt cgtgttgtcc atgatcatgg aatggtgggc gtgccagacg
    12601 taggagatgt ccatccgggg ccagggccgg ggacccgtca gttcggggat gccggggacg
    12661 tcccgctcgg tcgcccgggc aggatcgccc gggaagaccc agatgatgcc gtggcgggac
    12721 gccaccgggt agtcgcgcac cttcacttcg ggttcggcgc ggccgaagag atcgtgggcg
    12781 tagtgcacca cgcggccgtc cccgccatag gtccagccgt ggtactcgca ggtgaggtgg
    12841 cagccgttga ccacgcccgc ggacagtcgc agctggcggt gcgcgcagcg gtcctccagc
    12901 gcgcgcagca agccgtcgcg accacgccag accacgatcg ggtggcccca gaaggatgtg
    12961 gcgagggcct tcccggggtg caggcccctg tcgtactcga cggggtacca gtaatcgggg
    13021 tccatgcccg tcgccaggac cttctggcgc ctgcctcgcg cctgtccgaa gccgggcggg
    13081 ccggtcatga cggccccgtc gggcgccgtc ggggcagccg ggcgcggagc ggtggcggaa
    13141 cgacggcccg gcggcggccg atcagccccc gccgggcgaa gcaggcgtag gcctgctcga
    13201 cggcgcgggc gacactcgtc ggccggtagc ccagctcgct gacggcccgg gaacagtccg
    13261 cgcgccgctg ggagcggagg aaaccgaccg ccgcaggggt caaccggggc tcatgatgcg
    13321 ggaccagcag ggacaatgcg ggggcgacgg cccgggcgac gcccgacatc accgcgggcg
    13381 gcacccgcag ccgtggccgg gggcggtcgc agacctcgcc gtagaggtcg agcatctcgt
    13441 ccaccgtgtg gtactgagtg gacagcagat acttccgccc ggcggatcca tgccgcatgg
    13501 ccagcaggtg gcccgcgacg acatccgtgg cggagacgaa ctcgaaacca cccgggacgt
    13561 aggccagcag ccgtccgttc gcgaagtcca gcaacagccg gcccatccgg gacggcagat
    13621 agtcgtgcgg cccgatgatc gcggtggacg tcgcgacgac gacgtcgagt ccccgggcag
    13681 cagccttggc gcactcgtgc tccatcagca ccttgctgac ggtgtacggg gtgtgctgcc
    13741 cgaacgggta gaagaggtcc tcctccgtgc tcggaacacc gcgccgccaa ccggtcgcgc
    13801 tcaacgaccc ggtgaccacg acccgccgga cgtccgcccg ccatgcggcg gccagcacat
    13861 gatgactgcc cagcacattg acctcgtaga tctcacgctt cccaccgttc gccgtcgaga
    13921 cctgtgcggc gcagtggtag acctcctcac agccggtgac ggcgcgcccc accgcttccg
    13981 ggtccctcag atcgcccggc acccggtgca ccgccaggcc gtcgagcgcg gggccggcct
    14041 ctcctctgac cagcacacgc acctctcggc cttcggccag cagcccgcgt acgagattgg
    14101 ctcccagatg cccggtggcg cccgtgacaa ggatcatctc cgcccccttc atgagccctc
    14161 ccacgggcgt catgaatatg cgatcacatg cacatatagt agtttagcgg ctccgcaacg
    14221 tgagcagtag atgcccaggg acgcaacgac ggggacctcg agggggattc cgtgcagacc
    14281 gtggacgtgc tggtggcggg agcgggaccg gcgggctgca tgaccgcgct ggccttcgcc
    14341 cggcagggcg ccacggtcct ggtcgtggaa ccgggcacgg aacccacgcg acggctcgcc
    14401 ggcgagtggc tccatccggc cggggtgacg gcactgcgcc gcatgggaat caccccggcc
    14461 gaccgggagt tcacgacgaa ccacggcttc caactgcaca ccggcgacgg aaacccgccg
    14521 ctgcactgcc cgtaccccga cggcgtggcc ctgagcatgt accaccacgt cctcagcacc
    14581 ctgctgctcc gcacggtccg cgccgatccc ggcatcacac tccgccaagg cgaccgggtg
    14641 accgctgtcg ccacagccgg acgagcccac accacctgcg aagagatacg cgccggcctg
    14701 atcgtcggcg cggacggccg cgcctccaca gtgcgccgcc tgctccgccc cggcgaaccg
    14761 gcacccgcac cgctgtccca caccgccggg ctgctgctgc acggcgtccg gctgccccgg
    14821 ggcggatacg gccatgtctt cctcggcggc ccgggcccgg tactcgccta tcaagtggca
    14881 ccggacaccg tccgcctctg cctcgacgtc cccgtccccc gccccacgcc ctccgaaatc
    14941 cggggctact tgctgcacgg ctacacaacc gccctacccg ccgagctgcg cccggccttc
    15001 gccgacgtgc tgaccggcgg caagatccag tgggcggccg cccggttccg caggcggtcc
    15061 ttctacggcc gaggacgctg cgccctggtc ggtgacgcgg tcggacacgg gcacccactg
    15121 gccgcgctgg gcatgagcct cgcgctgctg gacagcgagt gcctggcccg ccggagcccg
    15181 gacatccacg cctacgccac cgaacggacc gcccgttcct gggccgccga acgcctcggc
    15241 gcggcactcc accgcaccct gaccggggcc gaccccgcat ccctgctcct gcgccgggcg
    15301 gccctcgatc tctggcggcg cgaccccggc caacggggcc tcgtcctggg gctgctgggc
    15361 atgcgggacg agcgccggag cgccttctgt gatgtcgtcg cacacgtgac ggccaatgcg
    15421 ctgacggatc tcgcccgcgc ggaacccacc cttcccggca caaccgcttc ggtacgccac
    15481 ctggtcggcc tcgccgactg gctgctctgg ctggccggcc ccgccgtcgg caccccccgc
    15541 ccaccccgcg cactgcgcgg gagattgcgt ggactcacgg tcatggggcc atgaccgcac
    15601 catcacgggc cggacaacgg cacgttggcg gagatcttga tgatctggga gtccaggacg
    15661 cagggggaag gtttcgcgtt gcggccctcg cactcgcgga ccaggcacca actgttgctc
    15721 gtgaaacgca caccacatgc gtcccgcact ccaccaacac ggccagttca gctgcggata
    15781 cacactccgg ccctgccccg ccccggcccg ggacgcccca aagacgcacc gccggcctcc
    15841 gtgtccggca cgtcagatcg gcgcggcggg acccggacct ggcgacgccc tcggcgccgc
    15901 cttgtcccgg atggtggcga gagtcgggat ccaggactgt cttcagcagg acagggcaga
    15961 ttggaactaa ggacgtgaac tgaacgatat tcacctcagg ggggattcat gtcgaacaac
    16021 cagccgaact cggtatatga cggagttgtt cgcagcggga gcccggattc cgcagtcgac
    16081 cgcgtggccg acttctacgg ggcctacatc gatgccgtct ccgacggcac cgatgacctg
    16141 gccgagcatc tccgcgccca ttacctcaca gaagacctcc ggcagcgttt ggccgcctgg
    16201 gaggagacca accacgccga cggcgtcctg cgcgcccagg acgtgcccac tggctgggaa
    16261 gtccgctacc acgattccgg tgccgggcac cttttcacca cggtcacgct cacctggggc
    16321 accggcccag gcgccgggca cagccaactg gcggtgcaga gcgacctggc caccaagctc
    16381 atctccgaca tcgagaacaa cccctccgag tcctgacagc gcacgtcacc tgctcggatg
    16441 ctgctccttg tcccagctgt cggagcgggg ccgacccagc ggctgcgatg gtcgacgccg
    16501 acgcctcgcg agactggctc cggcggcccc tcccccggca gcacctacgc gcgcaggagg
    16561 cttcgggaag gacgcggttg ggccagggtc cgctgcgaga gtgggggttg gactcggtat
    16621 ccatgaaatt attgggcggc caagggcgtt gatcacgcca tgacccaagg accagcgcct
    16681 cgcccactgt ccgacgaagc cctctccggg ctgctcggga agcagcagtt cggcacgctc
    16741 gccaccgtca agcgcagtgg ccacccccac ctgacgacca tgctgtacaa ctgggacccc
    16801 gaggcccgca ttttgcggtt ctcgacgacg gccgatcgca tcaaggtcgg gcacctgcgg
    16861 cgcgacccac gtgcgacgct gcatgtgcag ggcggcgacg tatggtcgtt cgctgtcgcc
    16921 gaaggcgagg ccgaagtctc agagatcacg acggttccag gcgacggggt tggccgggaa
    16981 ctgctggaga tgatcccgca ggccgcgaaa cctgacgatg aacgtgcgtt tctggagcag
    17041 ctggtcgccg agcgccgggt ggtcatccgg ttgaaggtga gccggctgta cggaacggcg
    17101 ctcgacatcg acggctaggc actgtccgat aggtcgtgtg accggctggc gttcatgtcg
    17161 ttccgctcgg tgtggggcag ggtggggcgg gcgatctgtc ggatcgggag tgggctcggc
    17221 tggagccgta cttgccgagg aaggtggggc ggggcggtcg ttggaagagt catcgcgggg
    17281 tgatcaatgg cattctcttc cggcagcgga ccggtgtccc gtggcgtggt ccgccggcac
    17341 ggttcgggat atggaaggcc gtgcacgaca ggcatcgcag gtggtcggcg gacggcgcgt
    17401 gggagagggt cctgcgggct gtccaggccg atgccgatgc ggaaggccgg atcgactgga
    17461 gcatggggcc tcgggccgtg cccatcagca cgccgcgggc gcccgcaccg gcgcgccgcg
    17521 tacccctgga caacgcggcc agcctgttca gcatcgtccg gacgaggccc cgggccgctc
    17581 ccgtggcggg ctcacccgca agatccacct cgccggtgag ggcggccgac gtccgcccgc
    17641 gtccgtcatc acaccaggcc agtggggcga cgccccgcaa ctgatcccgg tcctcgaacg
    17701 catccgcgtc ccacggcccg gcggcggtca tccgcgcacc cgccccgatc acctgggcgg
    17761 cgacaaagcg tacccgtccc gacagaaccg ccggtaccta cggcgccgac agatcaagca
    17821 caccatcccc gaacgcaagg accagcgggc caaccgcccg gcgccgcggc agcgcgggcg
    17881 gccgtcccac cggcttcgac aagacgatct acaaacgccg caacgaagcc aggcgaacga
    17941 tcaacgccct caagggcttc cgcgccatag ccacccgctt cgacaaaagg gcgtatatct
    18001 tccacagcac cgtcatcgtt gctgcccttc gcctatggct tcgctcatga ctttccaaac
    18061 agttcccagg cagggttcat acggacctcg ccgggttgcc cgtttcggcg atagcggttt
    18121 ggcttagtag atccgatttg agagtaccgg tcgatcgtta ccccagtcag gcccggccgc
    18181 cgtagggcgc ttgggtttgc cgggaaggtg ggactgaggt ggagcgaata tcccaggcgg
    18241 cagctcggct cggtcggctt ccagtgcgca tcagtggtgg cgtcccaacc caggacgtgg
    18301 tttcactgga tcgcggggac ccggactttt ccacccctgc ccccatcgtc gatgccatgg
    18361 accgggctct gcgagacggc tacacgcatt acggagacct caacggagat cccgaactcc
    18421 gcgcatacat agcagagcga gccagcgcgt atacgggtga cagatacgac gactcgcagg
    18481 tcctcatcac acctggttcg acggccggtc tggccactgc catctacgcc attgccgggc
    18541 caggcgaccg gatagtactg ttcgacccga cttaccccgc gtacgccgag caggccgcgc
    18601 tggccggtgc cactgtggtg cgcgtgccgt tccgagagga cggcggcctg cacctggagg
    18661 cactgcagga atccgtcgtg ggcgcccgcc tcctcgtgct gtgccatccg tccaacccca
    18721 ccggcgcagt gttttccgaa gcggatctgc gcgggctcgc cgctgtgctc gaaggaagcg
    18781 acaccatcgt cctcgccgac gaggcccacg cggacatcgt ctacgaccac cggccctaca
    18841 tctccaccat gggtatcccc gaactgcgcc cgcgcctggt gaactgccgt agtttctcca
    18901 agacctatgc catggccggc tggcggctgg gatacctgat cgcgccgccc gaactggcga
    18961 aggtgattcg gcggatccac ctcatctaca actgcggtgt gaactcggcg gttcagcggg
    19021 ccgggctgtt cgctttgcgg actgggacat cgctggtgat gcccatgctc caggagtacc
    19081 agcaccgtcg tgacctggtc gtggactgga tgcggcagac cgggttgctc cgcgggcgag
    19141 tcccggaagg cacgttctac gcctaccccc attatccgca ccccatcgga tccgtggaaa
    19201 tggtccggca tttgctgcgg tacggcgtat gcgtgcgagc cggtgccttt gacggcccag
    19261 gcggagagca ccatctgcgg atctcgttct ccacgaacac tacggacctg atcgaaggtc
    19321 tgtcccgatt ggagaaagga ttgcgtgcgc tatgagcccg aagtggacca gccgcgtgcc
    19381 caccctgctc gactgcactt tgcgcgaagg cccttatgaa tgccgattcg gctccgagga
    19441 gatggccatc atcgccaagc agctccagca gtccggtatc acccatatcg aggtgggtgc
    19501 cgagaccgga ctgggcacca acccgcaagt tgacgacatc gaccagatcc gtacggtcgc
    19561 cgccgcggcc ccgggcaccc gagtgggcgt catagccggc gcctcctcga cgacggtcga
    19621 cgacctgcgc cgggtggtgg acgcgggggc gggcttcatc agagttgccg cggcggtcac
    19681 cgactcgacc acggcgctgc cgctcatcga ggcggtcgcc gactggaacg tcccggtgac
    19741 gttcaatgcc atcaagtgct acgcagtcga gcagcaacag ttgctgtcca tcgccaaaga
    19801 tgtcacagcc gcaggcgccc acgtcttcta cctggtggac tccgcaggct ccatgctgcc
    19861 tcgtactgtg caccgacgca cggccgcact ccacgacctc ggcatccagg tcggtttcca
    19921 cggacacgac aacctggccc tcgcggtggc gaattccctg gcggccctcg acgccggcgc
    19981 gatcgctgcg gacggaacgc tcaggggcat cggccgcagc gcaggcaatg cccagctgga
    20041 agtgctggtc aaagctgctc agcagcacgg ctccctgacc gaagtggacg gcgacgcgct
    20101 gtgccgcctc tcggaggaac tcatcgccga gcgcaggctc cgtgaccgtg gcgtctcgtt
    20161 cctggacatc gccatggggg aaggccggtt ccactccgag cgccttgacc tcgcacgcga
    20221 ggtggcacat gcctaccagg tgcccctcga atccctggtc cgtgccacag gacagagcga
    20281 ccccgtcgct cccgaccgga acctgttgga acaaacggcg gccctgctac gcgcggaccc
    20341 gcctgccgaa gccgcccact cctggcccgg tcactggtga ggtgaagatc catgggcaag
    20401 acaagcaatc gcgtcaaggc catcgagggc caggtcgccc gaatcggccg actgggcgca
    20461 cagcccactg aggccgtggc ccaagaggtc atgaccctgc cccagccgca ggactgggtg
    20521 ctggactccg gcgaacacca gtcgggaggc tggtggacct gctcgctgct caacgcctcc
    20581 ggagacccgc gcgatgtgac gcttcaggac tgcgacccgg cccccacgac cttgctcgaa
    20641 cgcatgcctg ccacccggac gttgcttgaa tcgctgggac tgcactatat gtgggcacgg
    20701 ctcgcgcgac tggaggccaa gtccttcctg tgggagcacc gggactacgg caatctcagc
    20761 gaggccgaac gccaccggct gcatatcccg ctccatacga atccgtccgc ctatctggtg
    20821 acacgcggag cgaaggtgca catgtacgcg ggtcacatgt ggcggcttac cccgacccac
    20881 cagcacgggg tgtgcaacct cgacggcccg gaccgcatcc acctgctcct ggactgctac
    20941 gccgacgacg cctaccgaag ccgcgccgcg actgccgagc tcctcgacgg cgacgttgag
    21001 cagcttccgg acatcaccgc tgatcaactt gccgaggcga agatcaccgc ccgaaggctc
    21061 gccgagggcg gggacatctc cggcgccgag aatcgccttc tacggctgtt ctacctctac
    21121 gcgttgcccg aaggccggat ctacgacctc gtcatggacc tgcaccggac gctgggccgc
    21181 gaacaagatg tacggcgctg gcgcgagcac aagcgtttgg ccctcaaaca ggatgctgca
    21241 tagcgccgcc gttccttccc ttccggtcgg atctcggccg acccggagct gacggtcggc
    21301 cagtcgcccg acctgtcgga cacgccttag gacgtatcgg atccgtgctg gtcagagcca
    21361 ctcgctgagg actgcgacca gcacggtcgc ctcgtagcgg acggcaggct tgtcgtatct
    21421 cgtggccacg gcccggtggc acttgaggcg attgatcccg cactcgacgg catggcgctc
    21481 gcggtgttcg ttcttgccgg acttcggtgg ccgaccgcct cgggagccga gcttctggcg
    21541 gttgcggact cggtcctcgg ggaccgggat ggttgccctg atcccccgtc tgcggaagta
    21601 ggcccggttg cggcgagagt catacgcctt gtcggcccgg acccggtccg ggcgcctgcg
    21661 gggccgcccg cgccccagcc gggggaccgg aatcgcctcc aggaccggct cgaactgcgg
    21721 gtaatcaccc cgccgcccgg ctgtgatcag caccgacagc ggcttctgcc cctgctcgac
    21781 agcgaggtgg atcttggtgg tcagcccacc ccgggaacgt ccgggaccgt gatcggtcgg
    21841 ctctaccgca atgccgccgg gcggctcctt ttgcagatcc ccttctttcg gcgcaccagc
    21901 ggcgtgctgg tgggcccggc ctacgcaccg atggaaggta cgccccctgc tgcctgtggg
    21961 gccttcgtca tggggtgccg ccgcccgtac ccccgaggat ggccaggctg gcgggtttga
    22021 cggctgtc
//
