LOCUS       NZ_CP031320            21074 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces armeniacus strain ATCC 15676 chromosome.
ACCESSION   NZ_CP031320
VERSION     NZ_CP031320.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces armeniacus
  ORGANISM  Streptomyces armeniacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Draft genome of the type strain Streptomyces armeniacus ATCC 15676
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2018) Department Of Chemistry and Biomolecular
            Sciences, University Of Ottawa, D'Iorio Hall, 10 Marie Curie,
            Ottawa, Ontario K1N 6N5, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUL-2018
            Assembly Method                   :: SPAdes v. JULY-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003355155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:13:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,031
            CDSs (total)                      :: 6,963
            Genes (coding)                    :: 6,742
            CDSs (with protein)               :: 6,742
            Genes (RNA)                       :: 68
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 36 of 221
            Pseudo Genes (incomplete)         :: 204 of 221
            Pseudo Genes (internal stop)      :: 5 of 221
            Pseudo Genes (multiple problems)  :: 22 of 221
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:36:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7974518
            Orig. end                         :: 7995592
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031320.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="40"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            113..937
                     /locus_tag="DVA86_RS34470"
                     /old_locus_tag="DVA86_34725"
     CDS             113..937
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007451041.1"
                     /locus_tag="DVA86_RS34470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34725"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_208884156.1"
                     /transl_table=11
                     /translation="MPPTGSVPARRPLGTVTRGTTSPNRLRRMDRWIAHTHGAALRRSD
                     EPPVAVDLGYGAAPWTAVELLLRLRRVRGDAEVAGLEIDPERVAAAKPYERSGLTFGRG
                     GFEIPLPRPPLLIRAANVLRQYAEDDVPAAWERLCGRLAPGGLLVEGTCDEIGRRHVWV
                     ALGPEGPRTVTFAARLGSLTRPSDLAERLPKALIHRNVPGEAVHAFLRDFDRAWAAAAP
                     YAPYGARQRWVRAAHALGTAWPLVDGPRRWRHGEVTIGWSALAPRPSGPSGA"
     gene            complement(1103..1528)
                     /locus_tag="DVA86_RS34475"
                     /old_locus_tag="DVA86_34730"
     CDS             complement(1103..1528)
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540130.1"
                     /locus_tag="DVA86_RS34475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34730"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_208884157.1"
                     /transl_table=11
                     /translation="MDQPVLAAGCVLWRRRSPEEDCDGIELAVVHRPKYDDWSHPKGKL
                     KRGEDPLDGALREVREETGMECEPGAPLPTARYESQYRPKEVRYWAAEATGGSFLPNHE
                     VDRMAWLPPGAARDRLSYERDRELVDALLVALRTPGD"
     gene            complement(1609..2805)
                     /locus_tag="DVA86_RS34480"
                     /old_locus_tag="DVA86_34735"
     CDS             complement(1609..2805)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019355222.1"
                     /locus_tag="DVA86_RS34480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34735"
                     /product="CHAD domain-containing protein"
                     /protein_id="WP_245997487.1"
                     /transl_table=11
                     /translation="MPAAAPAAGPAGSAASAAPGAGAGDVLGAYLHTEAAEFLRSLRVH
                     GESAGSPEAVADAAAAVRQLRRSARRMSGALHTYRTLVDTGWADQLRTELGWLSGTLAR
                     EYAYAARLDRLLSALHRLASDGSAIGGGAGGAVGGSTGIGSGGTGGAAVSGAPSAKGGA
                     LPVGAARAGALLERQLTLARTRAHSAALQALGSSRFHAVADAVAVLASEAPITPDTDGR
                     PAEEVLPPLAEAAHRRLNEAVDILPLARAEHPYNAEALSRSLAAEVQGDAAWHQVRLLL
                     RLHRYAQEVLLRGTGAAADPDADQRLGPASRALDRHRDAAEAAAAAASAARTPRIAPAT
                     AYALGVLHADQRHEVEAARFAFGRLWTARTTETRTTETRTAETRTAETTRRAERGGTR"
     gene            complement(2732..3043)
                     /locus_tag="DVA86_RS35840"
     CDS             complement(2732..3043)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVA86_RS35840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_245997488.1"
                     /transl_table=11
                     /translation="MNGDVLLDFDDLDRELGTPQVKFTAGGPHTVLAAGQLWVAGEKGK
                     VRARGRRRGVAGVRADLGGGERDGGTGRLGAAGVRARGCTGGGARGVRGVGRAGGRCG"
     gene            3139..4581
                     /locus_tag="DVA86_RS34490"
                     /old_locus_tag="DVA86_34745"
     CDS             3139..4581
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014057332.1"
                     /locus_tag="DVA86_RS34490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34745"
                     /product="APC family permease"
                     /protein_id="WP_208884160.1"
                     /transl_table=11
                     /translation="MLRDTSTEESAGTAATPANLTGRLGTGAIVFMVVAAAAPLTVVGG
                     NVPLAIASGPGAGAPVGFAIASVILLVFAVGFVTMTPHVPEAGAFYAYATRGLGDRVGV
                     GTAGVALVAYTAIQVGVYGYMGWAANDVLKTFGGPTGVPWWVWSLATVAVVAFLGYRHI
                     ELSSKVLGVALVLEIAVVAVLDAVIVARGGEHGVSVESFTPDAVFSGPLGVAVLFALTG
                     FIGFEATAVFRNEARDPDRTIPRATYLAVIVIGAFYTVSCWALVLAAGTDEASGVAQKT
                     LDGDANMLMDTAEAYVGTALRDIMQVLLLSSLFACVLSFHNVIARYTFTLSRKGLAPAR
                     LGSVHPRHHSPSFSSVAQTVTALLLVCVFALLGLDPLVGVFGSMAGVATVGMVLLMLTT
                     SVAVVTFFAREPALAAGRTWQTRIAPALAVLGLLSSLWLVFANFTLITGGSTGVSIALA
                     AIPFAAFAAGLALGPARGGTRQ"
     gene            complement(4627..7944)
                     /locus_tag="DVA86_RS34495"
                     /old_locus_tag="DVA86_34750"
     CDS             complement(4627..7944)
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (15-444). E-value:
                     3e-175. Score: 575.1. Matches aSDomain:
                     nrpspksdomains_DVA86_RS34495_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327677.1"
                     /locus_tag="DVA86_RS34495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34750"
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_342776423.1"
                     /sec_met_domain="mod_KS (E-value: 3.1e-215, bitscore:
                     713.6, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.4e-88, bitscore:
                     295.4, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKENQRLADATPEPVAIVAVNCRFPGGADSPEAFWQLLADGADA
                     LSEMPANRGWDLDTLSGASGARTGGSATTRGAFVHDADEFDPQFFGMSPREALATDPQQ
                     RLLLETAWELLERAGINPTTLRGSRTGVFAGCSNQEYGSGLDEVPEGIEGHILTGNAGS
                     IVSGRIAYTLGLEGPAVTVDTSCSSSLVALHLAAQALRSGECDLALAGGVTVMSTPAAF
                     VEFSRQGGMAADGQCKAFAEGADGTGWGEGAGILLLERLTDARANGHQVLAVLRGSAIN
                     QDGASNGLTAPNGPAQQRVIRAALANGGLTTGDVDAVEAHGTGTSLGDPIEAHALLATY
                     GRDRDPEQPLWLGSVKSNIGHTQSAAGAAGLIKIVLALQHGVLPRTLRAEQPTSHVDWS
                     AGGGGVRLLTEPVEWPVRDGHVRRAGISSFGISGTNAHAILEQAPDTDADPAEPAEGTA
                     LPAVPWVLSARSADALRAQARRLLAHVTRAPEAAPADIGLSLATTRAALEHRAVVVGAD
                     RDALLEQLRHLAEDESAAGVVTGAVRRGGRTAFVFAGQGAQRLGMGRELYEAFPVDLLG
                     RTVRWAHVSQLTDLTGLLRGGELVLTTADALRGGAVRPYAYLAGLAEAGAAGVVVELPA
                     ADGDFADAMREAAAGMAFPVVLLARSVRFVEVTEAVHSRIVNEQYEEVRFAQRAHEVFT
                     ALSLEHAPPEVIVARAAALTDTAVVFEDVAHRVLAAAPGPGETGTEVLDDWERRSRLAP
                     DDWLYTPVDVHGQPWGRLVMPSAGAATPAGAPSAAAGGPAPAGGPRLGMVLERAAQALT
                     LRLMAEQNQADVRRRAQSGLISELTEGRIGTEAEALVRARAVGLRAGALYVPVAVRYAG
                     APSGPVAPSAEEALRRDRQFVAAVARTVAAVGVSSLTSTVRLGEVALVLSCPRPYDEDA
                     LLERFADVLGGQLPAGVPGRPEGEPRLRVGVGPSQPSLIAAARRLTDAAHTAEVAAAMT
                     GPERPFYRGEHLRLRGLLSVLRDNRHLRAFAESELHRLLDHEARKGSGHLDLLRQYLAV
                     NGNKNELARRTSLSRPALYARLAAIERLLDVRLDDPETRVCLYLALLARDLDPRTPD"
     CDS_motif       complement(6244..6297)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVA86_RS34495_0005"
                     /evalue="1.50E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="DVA86_RS34495"
                     /protein_end="567"
                     /protein_start="549"
                     /score="20.4"
                     /tool="antismash"
                     /translation="FVFAGQGAQRLGMGRELY"
     aSDomain        complement(6613..7899)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVA86_RS34495_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.00E-175"
                     /label="DVA86_RS34495_PKS_KS.1"
                     /locus_tag="DVA86_RS34495"
                     /protein_end="444"
                     /protein_start="15"
                     /score="575.1"
                     /tool="antismash"
                     /translation="VAIVAVNCRFPGGADSPEAFWQLLADGADALSEMPANRGWDLDTL
                     SGASGARTGGSATTRGAFVHDADEFDPQFFGMSPREALATDPQQRLLLETAWELLERAG
                     INPTTLRGSRTGVFAGCSNQEYGSGLDEVPEGIEGHILTGNAGSIVSGRIAYTLGLEGP
                     AVTVDTSCSSSLVALHLAAQALRSGECDLALAGGVTVMSTPAAFVEFSRQGGMAADGQC
                     KAFAEGADGTGWGEGAGILLLERLTDARANGHQVLAVLRGSAINQDGASNGLTAPNGPA
                     QQRVIRAALANGGLTTGDVDAVEAHGTGTSLGDPIEAHALLATYGRDRDPEQPLWLGSV
                     KSNIGHTQSAAGAAGLIKIVLALQHGVLPRTLRAEQPTSHVDWSAGGGGVRLLTEPVEW
                     PVRDGHVRRAGISSFGISGTNAHAILEQAP"
     CDS_motif       complement(6844..6888)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVA86_RS34495_0004"
                     /evalue="5.20E-04"
                     /label="PKSI-KS_m6"
                     /locus_tag="DVA86_RS34495"
                     /protein_end="367"
                     /protein_start="352"
                     /score="12.4"
                     /tool="antismash"
                     /translation="GSVKSNIGHTQSAAG"
     CDS_motif       complement(6949..6993)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVA86_RS34495_0003"
                     /evalue="2.20E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="DVA86_RS34495"
                     /protein_end="332"
                     /protein_start="317"
                     /score="13.3"
                     /tool="antismash"
                     /translation="VEAHGTGTSLGDPIE"
     CDS_motif       complement(7369..7416)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVA86_RS34495_0002"
                     /evalue="3.40E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="DVA86_RS34495"
                     /protein_end="192"
                     /protein_start="176"
                     /score="19.0"
                     /tool="antismash"
                     /translation="GPAVTVDTSCSSSLVA"
     CDS_motif       complement(7618..7644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVA86_RS34495_0001"
                     /evalue="1.60E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="DVA86_RS34495"
                     /protein_end="109"
                     /protein_start="100"
                     /score="8.3"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     gene            complement(8045..9298)
                     /locus_tag="DVA86_RS34500"
                     /old_locus_tag="DVA86_34755"
     CDS             complement(8045..9298)
                     /NRPS_PKS="Domain: PKS_KR (14-132). E-value: 2.3e-46.
                     Score: 150.0. Matches aSDomain:
                     nrpspksdomains_DVA86_RS34500_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (225-311). E-value: 6.9e-30.
                     Score: 95.2. Matches aSDomain:
                     nrpspksdomains_DVA86_RS34500_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (335-417). E-value:
                     1.5e-07. Score: 24.1. Matches aSDomain:
                     nrpspksdomains_DVA86_RS34500_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF020243.4"
                     /locus_tag="DVA86_RS34500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34755"
                     /product="beta-ketoacyl reductase"
                     /protein_id="WP_208884163.1"
                     /sec_met_domain="adh_short (E-value: 3.8e-40, bitscore:
                     136.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.3e-13, bitscore:
                     48.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSDPAFTPIRIGGDAADRDALKGLLAGIPADRPLTGVVHTAGVL
                     DDGVIGSLTPERLDTVLRPKADAVTNLHELTRDADLAAFVVFSSSAGVLGSPGQGNYAA
                     ANAYLDTLAARRRSDGLPATSLAWGPWSQTTGMTSGLGDADLRRMARAGLPALRPEQGL
                     ALFDLALDQPGPAVLPMAVDTRALGGTGTVPPLLRGLVRTGTRRTAASGAAGADSADSL
                     SRRLAGLAPAERHRTVLDTVCTQVAGVLGYGSGGDVGPEQTFKELGFDSLTSVELRNRL
                     GGALGVPLPSTLVFDYPTPSALTTHVCAELFPDGGTGGATDGRTGAGAETSARADDEAA
                     IRTALATVPIDALRASGVLDTVLALAGSTGTATGTADGTGNDAAADGGADSDADGGTDA
                     YEELEVDDLVRLALGDDG"
     aSDomain        complement(8048..8293)
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVA86_RS34500_PKS_Docking_Cterm.
                     1"
                     /evalue="1.50E-07"
                     /label="DVA86_RS34500_PKS_Docking_Cterm.1"
                     /locus_tag="DVA86_RS34500"
                     /protein_end="417"
                     /protein_start="335"
                     /score="24.1"
                     /tool="antismash"
                     /translation="DDEAAIRTALATVPIDALRASGVLDTVLALAGSTGTATGTADGTG
                     NDAAADGGADSDADGGTDAYEELEVDDLVRLALGDDG"
     aSDomain        complement(8366..8623)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVA86_RS34500_PKS_PP.1"
                     /evalue="6.90E-30"
                     /label="DVA86_RS34500_PKS_PP.1"
                     /locus_tag="DVA86_RS34500"
                     /protein_end="311"
                     /protein_start="225"
                     /score="95.2"
                     /tool="antismash"
                     /translation="LAGLAPAERHRTVLDTVCTQVAGVLGYGSGGDVGPEQTFKELGFD
                     SLTSVELRNRLGGALGVPLPSTLVFDYPTPSALTTHVCAEL"
     aSModule        complement(8366..9256)
                     /domains="nrpspksdomains_DVA86_RS34500_PKS_KR.1"
                     /domains="nrpspksdomains_DVA86_RS34500_PKS_PP.1"
                     /incomplete
                     /locus_tags="DVA86_RS34500"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(8903..9256)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVA86_RS34500_PKS_KR.1"
                     /evalue="2.30E-46"
                     /label="DVA86_RS34500_PKS_KR.1"
                     /locus_tag="DVA86_RS34500"
                     /protein_end="132"
                     /protein_start="14"
                     /score="150.0"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="DAADRDALKGLLAGIPADRPLTGVVHTAGVLDDGVIGSLTPERLD
                     TVLRPKADAVTNLHELTRDADLAAFVVFSSSAGVLGSPGQGNYAAANAYLDTLAARRRS
                     DGLPATSLAWGPWS"
     CDS_motif       complement(8948..9055)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVA86_RS34500_0001"
                     /evalue="7.20E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="DVA86_RS34500"
                     /protein_end="117"
                     /protein_start="81"
                     /score="63.6"
                     /tool="antismash"
                     /translation="AAFVVFSSSAGVLGSPGQGNYAAANAYLDTLAARRR"
     gene            <9246..10004
                     /gene="ispG"
                     /locus_tag="DVA86_RS34505"
                     /old_locus_tag="DVA86_34760"
                     /pseudo=""
     CDS             <9246..10004
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020553108.1"
                     /locus_tag="DVA86_RS34505"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34760"
                     /product="(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate
                     synthase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SAASPPIRIGVNAGSLDKRLLRKYGKATPEALVESALWECSLFEE
                     HGFRDIKISVKHNDPVTMIAAYRQLASRCDYPLHLGVTEAGPAFQGTIKSAVAFGVLLS
                     EGIGDTIRVSLSAPPVEECKAGEQILQSLGLRPRHLEIVSCPSCGRAQVDVYTLTEQVN
                     AAFEGFPHPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVET
                     LVEEALRLTEGLPEDSVQDLPEDTAVEVAS"
     gene            10001..11074
                     /locus_tag="DVA86_RS34510"
                     /old_locus_tag="DVA86_34765"
     CDS             10001..11074
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003957287.1"
                     /locus_tag="DVA86_RS34510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34765"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_208884165.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.5e-47, bitscore:
                     158.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLTTTADGPDLDGVPAAVDVLLDGFFDRKAGRGRAPHLPHLVEL
                     LRAFTKGGKRLRPVLCARGWQAAGGGDPAAVLPAAASLELFHTFALIHDDVMDRSDTRR
                     GRPTVHRLLAARARRHPHLLDAERFGDSGAILVGDLAMVWSDELFHDCGLPPERLAAAR
                     PFLDAMRGEVMHGQYLDVLSCTDFDSGLDAALNVIRYKTARYTVERPLQLGVALAGGGP
                     PLLDACSAYGLPVGEAFQLRDDVIGVFGDPAVTGKSCLDDLREGKHTALLALALECADA
                     AQARTLRALVGDPELDEEGAARIRSVLLSSGALDTVEHMITERRRRALRALEQAPFPAA
                     TRSALQQLAVDATERTS"
     gene            11071..12036
                     /locus_tag="DVA86_RS34515"
                     /old_locus_tag="DVA86_34770"
     CDS             11071..12036
                     /EC_number="1.17.7.4"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051745 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate reductase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948231.1"
                     /locus_tag="DVA86_RS34515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_34770"
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="WP_208884166.1"
                     /transl_table=11
                     /translation="MTAHTPPVPAPSGRVLLAAPRGYCAGVERAVAAVERALEKYGPPV
                     YVRKQIVHNTHVIRTLERKGAVFVEETDDVPEGGTVLFSAHGVAPEVHEQAAARRLTAI
                     DATCPLVTKVHREALRFAEEGYDILLIGHEGHEEVIGTMGEAPDRVQLVDGPDAVDGVC
                     VRDERRVVWLSQTTLSVDETMETVERLRERFPALVSPPSDDICYATQNRQLAVRQLAAD
                     CELVIVVGSRNSSNSARLAEVALQAGAAASYLVDSAQEAREEWLRGVSTVGVTSGASVP
                     DVLVDELLVWLAGRGYADVGIVTATEERQRFALPRELARS"
     gene            complement(<12188..>12466)
                     /locus_tag="DVA86_RS35850"
                     /pseudo=""
     CDS             complement(<12188..12466)
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009715706.1"
                     /locus_tag="DVA86_RS35850"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="ADP-ribosylglycohydrolase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGGTAGEALSRAVACALVAGDVQHGLLLGVTHGGDSGATGSICGN
                     LLGTINGETALPPGWVAELEGRATILELADDFAMEMTQGPALHSPASS"
     gene            12615..13868
                     /locus_tag="DVA86_RS34525"
                     /old_locus_tag="DVA86_34780"
     CDS             12615..13868
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVA86_RS34525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DVA86_34780"
                     /product="hypothetical protein"
                     /protein_id="WP_208884169.1"
                     /transl_table=11
                     /translation="MLAETVARLDADRTATAAAGPATSAGASDGREYGPGEHTVRAVRC
                     AFSELALSFTLFGHHRFEQALRALPAHTALNDLPPDCPEPDRALPGHTESCPHCREFLR
                     LNPAYACLPQRRARLLQDTVDLAVRARLALARAALTGGDGGLERAYEEWAEAIAVSGRA
                     AMTVRTKMAVLRMVLGRADALSDEDSVRRGSCLDEAISIVERALPLLGPPGRQPLSAKL
                     SELLAVRGVWGGYGCAEYDIRPDMVRAEADLRRALELNPESVYARDNLVRVLVFGLDPR
                     PGTGSRVHKLTVLLEAFRLLHGGLERLPTHARYWETLGDALEDLESLLLGGLSSQRLLD
                     HLVQVPDEVERAQGDAAARARELLEEARRLRDAQGDTAGALHLLARATRAHPSNADVRL
                     ELLRTTEQRLNELCEPGA"
     gene            13950..14417
                     /locus_tag="DVA86_RS34530"
                     /old_locus_tag="DVA86_34785"
     CDS             13950..14417
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVA86_RS34530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DVA86_34785"
                     /product="hypothetical protein"
                     /protein_id="WP_208884170.1"
                     /transl_table=11
                     /translation="MFKDPLTAWHGPFPYDVLAPVGVTPATTHSEMQDVSFDLMVQRLM
                     TPETQTAWNELRTLQKRLLVDAVLWDVDPEAEIATARQELDEALSDPGEPPEVAACLAP
                     PGADALDWLVEELDGVELNAPEPALPDEADDALSGAPVPPGLLDELIRFDR"
     misc_feature    complement(14962..16396)
                     /note="23S ribosomal RNA rRNA prediction is too short"
     misc_feature    15118..15128
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     assembly_gap    16397..18230
                     /estimated_length=1834
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     misc_feature    complement(18259..18268)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     rRNA            complement(18537..19987)
                     /db_xref="RFAM:RF00177"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="DVA86_RS34540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="DVA86_34810"
                     /product="16S ribosomal RNA"
     gene            complement(18537..19987)
                     /locus_tag="DVA86_RS34540"
                     /old_locus_tag="DVA86_34810"
     misc_feature    complement(19632..19648)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.97"
                     /tool="antismash"
ORIGIN
        1 acaacaccga aagggttgac tcgcatttcg gctttgccaa atcgtgacgt ggggcacttc
       61 ggcggcgggc gggacgtacg ggttgtccgc gtcggcgccc taagctctgc gcatgccccc
      121 gaccggttcc gtgcccgcgc gccgccctct cgggaccgtg acccgcggaa cgaccagccc
      181 gaaccggctg cgccgcatgg accgctggat cgcccacacc cacggcgcgg ccctccgccg
      241 ttccgacgag ccacccgtcg cggtcgacct cggctacggc gcggccccgt ggaccgccgt
      301 cgaactgctg ctgcgcctcc gccgcgtacg cggcgacgcg gaggtcgccg ggctcgagat
      361 cgaccccgag cgcgttgcgg cagcgaagcc gtacgaacgc tccggcctca ccttcggccg
      421 cggcggcttc gagatcccgc tgccacgccc gccactgctc atacgggcgg cgaacgtact
      481 gaggcagtac gcggaggacg acgttcctgc ggcgtgggag cggctgtgcg ggcggctggc
      541 gcccgggggc ctgctggtgg agggcacctg cgacgagatc ggccgcaggc acgtgtgggt
      601 ggcactcggg ccggaggggc cgcgcacggt cacgttcgcg gcgcggctgg gttcgctgac
      661 gcgaccgtcc gacctcgccg aacggctgcc gaaggcactg atccaccgga acgtgccggg
      721 ggaggcggtg cacgcgttcc tccgcgactt cgaccgcgcg tgggcggcgg ccgcgccgta
      781 cgccccgtac ggcgcgcgcc agcggtgggt ccgcgcggcg cacgccctgg gtacggcgtg
      841 gccgctggtg gacgggccgc ggaggtggcg gcacggcgag gtgacgatcg gctggtccgc
      901 cctcgccccc cgaccttccg gcccgtccgg cgcttgagga cagccaccag ccacaacggg
      961 cccgcgcccg gcacgcttcg gttccccatc ggaccccgca ccgcgacgcg gccgcccccg
     1021 tccgtcctcg aacgccggac ggactggata tggcaagcgc cttgcgccca agtgcaggcc
     1081 cgcacagggc tggcgagcgt cctcagtcgc cgggcgtcct cagagccacc agcagcgcgt
     1141 ccaccagttc gcggtcccgc tcgtacgaca ggcggtcgcg cgccgcaccc ggcggcagcc
     1201 aggccatgcg gtcgacctcg tggttcggga ggaaggagcc gccggtggcc tcggccgccc
     1261 agtagcggac ctccttcggc cggtactggg actcgtaccg cgccgtcggc agcggcgcac
     1321 ccggctcgca ctccatgccg gtctcctcgc gcacctcgcg cagcgcgccg tccagcgggt
     1381 cctcgccgcg cttgagcttg cccttcgggt gcgaccagtc gtcgtacttc ggccggtgga
     1441 cgaccgccag ctcgatgccg tcgcagtcct cctcgggcga gcggcgccgc cacaggacgc
     1501 acccggcggc cagcaccggc tggtccatga cgtcgcagtc cgcaggccgc gccgccggcc
     1561 gcgccgccgc gtctcgcgga cccgaatcgg ggccggggcc ggaggccgtc atcgcgtgcc
     1621 gcccctctcc gccctgcgcg tcgtctcggc cgtacgcgtc tcggccgtac gcgtctccgt
     1681 cgtacgcgtc tccgtcgtac gcgccgtcca cagccgcccg aacgcgaacc gcgccgcctc
     1741 cacctcgtgc cgctggtccg cgtgcagcac gcccagggcg tacgcggtgg ccggtgcgat
     1801 gcgcggcgta cgggccgccg acgcggccgc ggcggcggcc tccgccgcgt cgcggtgccg
     1861 gtcgagcgcc cggctggccg ggcccagccg ctggtcggcg tccgggtcgg ccgccgcgcc
     1921 cgtgccccgc agcagcacct cctgtgcgta gcggtgcagc cgcagcagca gccgtacctg
     1981 gtgccaggcc gcgtccccct gcacctccgc ggccagcgaa cgggagagcg cctccgcgtt
     2041 gtacgggtgc tccgcgcgtg ccagcgggag gatgtcgacc gcttcgttca ggcggcggtg
     2101 cgccgcctcc gccagcggcg gaagcacctc ctccgccggg cggccgtccg tgtcgggggt
     2161 gataggcgcc tccgaggcga gtacggcgac ggcatccgcg acggcgtgga agcgcgacga
     2221 gccgagcgcc tgcagcgccg cggagtgtgc gcgcgtacgg gccagggtga gctgccgttc
     2281 cagcagcgcg cccgcgcgcg cggcgcccac cggcagggca ccgcccttcg ccgacggggc
     2341 gccggaaacg gcagcaccgc cggtgccgcc ggagccgatg ccggtggaac cgccgacggc
     2401 accgcccgcg ccacccccta tggcgctgcc gtcgctcgcc agccggtgca gcgcggacag
     2461 cagccggtcc agccgggcgg cgtacgcgta ctcgcgcgcc agcgtgcccg acagccagcc
     2521 gagttcggtg cgcagctggt cggcccagcc ggtgtcgacc agcgtgcggt acgtgtgcag
     2581 cgcgccgctc atccggcggg cggaccggcg gagttggcgt acggctgccg ccgcgtccgc
     2641 caccgcctcg gggctgccgg cgctctcgcc gtggacgcgc aggctgcgca ggaactcggc
     2701 ggcctccgtg tgcaggtacg cgccgagcac gtcacccgca ccggcccccg gcgcggccga
     2761 cgccgcggac cccgcgggcc ccgccgccgg tgcagccgcg ggcacggacg ccggcggcac
     2821 cgaggcggcc ggtgccgccg tcgcgctctc cgccgccgag gtccgcgcgg acgcccgcga
     2881 cgccacgcct ccgcccccgc gcccgcacct tccccttctc acccgccacc cacagctggc
     2941 ctgccgccag cacggtatgc ggtccgcccg ccgtgaactt cacctgcggc gtgcccaact
     3001 cccggtccag gtcgtcgaag tcgagcagca cgtccccgtt catccggccc agcacggcgc
     3061 cgtcgacgga gccgggcgca tcgcatgttc accgaccgca accgcccccg cccccgcaac
     3121 cgccacagag gacagctcat gctgagagac acctccacgg aagaatccgc cgggaccgcc
     3181 gcgacccccg cgaacctcac ggggcggctc ggcaccggcg cgatcgtgtt catggtggtc
     3241 gccgccgccg caccgctcac cgtcgtcggc ggcaacgtcc cgctcgccat cgccagcggc
     3301 cccggcgcgg gagcgcccgt cggcttcgcc atcgcctccg tcatcctgct ggtcttcgcc
     3361 gtcggcttcg tcacgatgac gccgcacgtg cccgaggccg gtgccttcta cgcgtacgcc
     3421 acccgcggcc tcggcgaccg ggtcggcgtc ggcacggcgg gcgtcgcgct cgtcgcctac
     3481 acggcgatcc aggtcggcgt ctacggctac atgggctggg ccgcgaacga cgtgctcaag
     3541 accttcggcg gccccaccgg cgtgccctgg tgggtgtggt cgctcgcgac cgtcgccgtc
     3601 gtggccttcc tcggctaccg ccacatcgaa ctcagctcca aggtcctcgg cgtcgccctc
     3661 gtcctggaga tcgccgtcgt ggccgtcctg gacgcggtca tcgtggcgcg cggcggcgaa
     3721 cacggcgtca gcgtcgagtc gttcacaccc gacgcggtgt tctccgggcc gctgggcgtc
     3781 gcggtgctgt tcgccctcac cgggttcatc ggcttcgagg ccacggccgt cttccggaac
     3841 gaggcccgcg acccggaccg tacgatcccc cgcgccacgt acctcgccgt catcgtcatc
     3901 ggcgccttct acacggtgtc ctgctgggcc ctggtgctcg ccgcgggcac cgacgaggcc
     3961 tccggcgtgg cgcagaagac cctcgacggc gacgccaaca tgctgatgga caccgccgag
     4021 gcgtacgtcg gcacggccct ccgcgacatc atgcaggtgc tgctgctgag cagcctgttc
     4081 gcctgcgtgc tgtcgttcca caacgtcatc gcgcgctaca ccttcaccct ctcccgcaag
     4141 ggcctcgccc ccgcccgcct cggctccgta cacccgcggc accactcgcc gtcgttctcc
     4201 tccgtggccc agacggtgac cgcgctgctc ctggtctgcg tcttcgcgct gctcggactc
     4261 gacccgctgg tcggcgtgtt cggctccatg gccggagtcg cgaccgtcgg catggtcctg
     4321 ctgatgctca ccacgtcggt ggccgtggtc acgttcttcg cccgcgaacc cgcactcgcc
     4381 gcgggccgca cctggcagac ccggatcgcc ccggcgctcg ccgtgctggg cctgctgtcg
     4441 agcctgtggc tggtcttcgc caacttcacg ctgatcacgg gcggcagcac gggcgtgagc
     4501 atcgccctgg cggcgatccc cttcgcggcc ttcgccgcgg gcctggccct cggccctgcc
     4561 cgcggcggca cgcggcagta gacgtctccg ttcccgccgc ggccgccgca cgtcgagggc
     4621 ggtgggtcag tccggtgtgc gcgggtccag gtcgcgggcg agcagggcga ggtagaggca
     4681 gacgcgggtc tcggggtcgt ccaggcgtac gtccagcagc cgttcgatcg cggcgaggcg
     4741 cgcgtacagc gccgggcggc tcaggctcgt acggcgggcc agctcgttct tgttgccgtt
     4801 gacggcgagg tactgccgga gcaggtcgag atggccggag cccttgcggg cctcgtggtc
     4861 gaggaggcgg tgcagttcgg actcggcgaa cgcccgcagg tgccggttgt cgcgcaggac
     4921 ggacaggagg ccgcgcagcc gcaggtgttc gccgcggtag aagggccgtt ccgggccggt
     4981 catggcggcg gcgacctcgg cggtgtgggc ggcgtcggtg agccgccggg cggcggcgat
     5041 cagcgacggc tgggacgggc cgacaccgac acgcaggcgc ggctctccct caggacggcc
     5101 ggggacgccc gcgggcagct ggccaccgag gacgtcggcg aagcgctcca gcagcgcgtc
     5161 ctcgtcgtac ggccgcgggc aggacagcac cagtgcgacc tcccccagcc gtacggtgct
     5221 ggtcagggac gacaccccga ccgccgccac cgtacgggcg acggccgcca cgaactgccg
     5281 gtcccggcgc agcgcctcct ccgcggacgg cgcgacgggc ccggagggcg cgcccgcgta
     5341 ccgtacggcg accggtacgt acagcgcgcc ggcgcgcagc ccgaccgcgc gggcccgtac
     5401 gagcgcctcc gcctcggtgc cgatacggcc ctccgtcagc tcgctgatca gcccgctctg
     5461 ggcgcggcgc cgtacgtcgg cctggttctg ctcggccatg agccgcaggg tcagcgcctg
     5521 cgcggcgcgc tccaggacca tgccgagccg gggcccgccg gccggagcgg gcccgccggc
     5581 ggcggcagag ggagcaccgg cgggagtagc agcgccggcg gacggcatga cgaggcgccc
     5641 ccagggctgt ccgtgcacgt cgacgggggt gtacagccag tcgtcggggg ccagccggga
     5701 gcggcgctcc cagtcgtcca ggacctcggt gccggtctcg ccggggccgg gcgccgcggc
     5761 cagcacgcgg tgggcgacgt cctcgaagac cacggcggtg tccgtgaggg cggcggcgcg
     5821 ggcgacgatc acctcgggcg gcgcgtgctc caggctgagc gcggtgaaca cctcgtgggc
     5881 gcgctgggcg aaccggacct cctcgtactg ctcgttgacg atgcggctgt gcaccgcctc
     5941 cgtgacctcc acgaagcgga cgctgcgcgc gagcagcacc accgggaacg ccatcccggc
     6001 cgcggcctcg cgcatggcgt cggcgaagtc gccgtcggcg gcggggagtt cgacgacgac
     6061 gccggccgcg cccgcctccg cgagcccggc caggtaggcg tacgggcgga ccgcgccgcc
     6121 gcgcagcgcg tccgcggtgg tgaggacgag ttcgccaccg cgcagcagcc cggtgaggtc
     6181 cgtcagctgg ctgacgtggg cccagcggac ggtgcgtccg agcaggtcca ccgggaacgc
     6241 ctcatacagc tcacgcccca tccccaaccg ctgcgcaccc tgacccgcaa aaacaaacgc
     6301 cgtacgccca ccccgacgca ccgcacccgt caccacaccc gccgccgact cgtcctccgc
     6361 gaggtggcgc agttgctcca gcagggcgtc gcggtcggcg cccacgacca ccgcacggtg
     6421 ttccagtgcc gcgcgggtgg tggccaggga gaggccgatg tcggccggtg ccgcttccgg
     6481 ggcgcgcgtc acgtgggcga gcagccgccg tgcctgtgcg cgcagcgcgt ccgcgctccg
     6541 cgcggacagc acccacggca cggccggaag cgccgtcccc tccgccggtt cggcgggatc
     6601 ggcatccgtg tccggggcct gttccaggat ggcgtgtgcg ttcgttccgc tgatgccgaa
     6661 cgaggagatg cccgcacgcc gtacgtgccc gtcccgtacg ggccactcca ccggctccgt
     6721 cagcagccgt acgccaccgc cgcccgccga ccagtcgacg tgtgaggtgg gctgctcggc
     6781 gcggagggtg cgcggcagca cgccgtgttg cagcgccagc acgatcttga tgagtccggc
     6841 ggcgcccgcg gcggactggg tgtggccgat gttggacttc accgagccga gccacaacgg
     6901 ctgttcgggg tcacggtccc gcccgtacgt ggccagcagg gcgtgggcct cgatggggtc
     6961 gcccagcgac gtgccggtgc cgtgcgcctc caccgcgtcc acgtcgcctg tggtgagtcc
     7021 gccgttggcg agggccgcgc ggatgacgcg ctgctgtgcg ggcccgttgg gcgcggtgag
     7081 gccgttcgac gcgccgtcct ggttgatggc ggagccgcgg aggacggcga gcacctggtg
     7141 cccgttggcg cgggcgtccg tgaggcgttc gaggagcagg atgcccgcgc cctcgcccca
     7201 gcctgtgccg tcggcgccct cggcgaacgc cttgcactgg ccgtcggccg ccatgccgcc
     7261 ctggcggctg aactcgacga acgccgccgg tgtcgacatc accgtcacgc cgcccgccag
     7321 cgccaggtcg cattcgccgc tgcgcagggc ctgtgcggcc aggtgcaggg cgacgagcga
     7381 cgacgagcag gacgtgtcga cggtcaccgc ggggccctcc aggcccagcg tgtacgcgat
     7441 gcgcccggag acgatgctgc ccgcgttgcc ggtcaggatg tggccctcga tgccctcggg
     7501 cacctcgtcg agcccggagc cgtactcctg gttgctgcat ccggcgaaga cgcccgtacg
     7561 gctgccgcgc agcgtcgtgg ggttgatgcc ggcgcgttcc agcagttccc aggcggtctc
     7621 cagcagcagc cgctgctgcg ggtcggtggc cagcgcctcg cgcggtgaca tgccgaagaa
     7681 ctgggggtcg aactcgtccg cgtcgtgcac gaacgcgccc cgcgtcgtgg cgctgccgcc
     7741 cgtacgggcg ccgctggcgc cgctcagcgt gtcgaggtcc cagccgcggt tggcgggcat
     7801 ctcggagagc gcgtcggcgc cgtcggcgag cagctgccag aacgcctcgg ggctgtcggc
     7861 gccgccgggg aagcggcagt tgacggcgac gatcgccact ggttccgggg tggcgtcggc
     7921 cagccgctgg ttctccttct tcagctggtc gttctcgcgc agcgatgccc tgagggctgc
     7981 gactactcgg tcctcggacg tggccatctt cagctccgct ggtggtgcgt catgggtcgt
     8041 gtggtcagcc gtcgtcgccg agggcgagcc gtacgaggtc gtcgacctcc agctcctcgt
     8101 acgcgtcggt gccgccgtcg gcgtcggagt ccgcgccgcc gtcggcagcg gcgtcgttgc
     8161 cggtgccgtc ggccgtgccg gtggcggtgc ccgtgctgcc ggcgagggcc aggacggtgt
     8221 ccaggacgcc ggaggcgcgg agggcgtcga tcgggaccgt ggcgagcgcc gtacggatcg
     8281 ccgcttcgtc gtccgcgcgc gcggaggtct ccgcgcccgc gcccgtacgg ccgtcggtgg
     8341 cgccgccggt gccaccgtcg gggaacagtt ccgcgcacac gtgcgtggtc agtgcggacg
     8401 gggtggggta gtcgaagacg agtgtggacg gcagcggtac gccgagcgcg ccgccgagcc
     8461 ggttgcgcag ttcgacggag gtgagcgagt cgaagcccag ctccttgaag gtctgctcgg
     8521 ggccgacgtc gccgcccgac ccgtagccga ggacgccggc gacctgggtg cagacggtgt
     8581 cgagcaccgt acggtgccgt tcggcgggcg ccaggcccgc cagccggcgg ctgagcgagt
     8641 cggcgctgtc cgctccggcg gcgccggacg cggccgtacg gcgggtgccc gtgcggacga
     8701 ggccgcgcag cagcggcggc acggtgccgg tgccgcccag ggcgcgggtg tccacggcca
     8761 tgggcaggac ggcggggccg ggctggtcga gcgccaggtc gaagagggcg aggccctgtt
     8821 cggggcgcag ggcgggcagc ccggcgcgtg ccatgcggcg gaggtcggcg tcgccgagtc
     8881 cgctggtcat gccggtggtc tgggaccagg ggccccaggc gagcgacgtc gcgggcaggc
     8941 cgtcggagcg gcggcgggcc gcgagggtgt ccaggtaggc gttggcggcg gcgtagttgc
     9001 cctggcccgg tgagccgagc acgccggcgg aggacgagaa gacgacgaac gcggcgaggt
     9061 cggcgtcccg ggtcagctcg tgcaggttgg tcaccgcgtc cgccttgggg cgcagcaccg
     9121 tgtcgagccg ttcgggggtc agcgagccga tcacgccgtc gtccagaacg cccgccgtgt
     9181 gcacgacgcc cgtcagcgga cggtcggcgg gaatgcccgc gagcagaccc ttcagcgcgt
     9241 cacggtcagc ggcgtcgccg ccgatccgga tcggggtgaa cgcggggtcg ctggacaagc
     9301 ggctgctgcg gaagtacggg aaggcgactc cggaggcgct ggtggagtcg gcgttgtggg
     9361 agtgctcgct gttcgaggag cacggtttcc gcgacatcaa gatctccgtc aagcacaacg
     9421 acccggtgac gatgatcgcg gcgtaccggc agttggcgtc ccgctgcgac tacccgctgc
     9481 acctgggggt gaccgaggcc ggtcccgcgt tccagggcac catcaagtcg gccgtcgcct
     9541 tcggcgtact gctgtcggag ggcatcggcg acaccatccg ggtctcgctg tccgcgccgc
     9601 ccgtggagga gtgcaaggcg ggggagcaga ttctgcagtc gctggggctg cgcccgcgcc
     9661 atctcgagat cgtctcgtgc ccctcctgcg gccgcgcaca ggtcgacgtc tacacgctca
     9721 ccgagcaggt caacgccgcg ttcgagggct tcccgcaccc gctgcgcgtg gccgtcatgg
     9781 gctgcgtcgt gaacggcccc ggcgaggccc gcgaggcgga cctcggggtc gcgtcgggca
     9841 acggcaaggg gcagatcttc gtgaagggcg aggtcatcaa gaccgtgccc gagtcgaaga
     9901 tcgtcgagac gctcgtggag gaggcactcc gcctcaccga gggccttccg gaggactccg
     9961 ttcaggacct tcccgaggac accgccgtgg aggtggcgtc atgaccctca ccacgaccgc
    10021 cgacggaccg gacctcgacg gcgtgcccgc cgccgtggac gtactgctcg acgggttctt
    10081 cgaccgcaag gccggccgcg gccgggcccc gcacctgccc catctcgtcg agctgctgcg
    10141 cgcgttcacg aagggcggca agcgcctgcg gcccgtgctg tgcgcccgcg gctggcaggc
    10201 ggcgggcggc ggcgacccgg ccgccgtact ccccgccgcg gcctccctgg agctgttcca
    10261 caccttcgcg ctgatccacg acgacgtgat ggaccgcagc gacacccggc gcggacggcc
    10321 caccgtgcac cggctgctgg ccgcgcgcgc ccgccgccac ccgcacctgc tggacgccga
    10381 acgcttcggc gacagcggcg cgatcctggt cggcgacctg gccatggtct ggtccgacga
    10441 gctgttccac gactgcggcc tgccgccgga acggctcgcc gccgcccggc cgttcctcga
    10501 cgcgatgcgc ggcgaggtca tgcacggcca gtacctcgac gtgctcagct gcaccgactt
    10561 cgacagcggt ctggacgccg ccctgaacgt catccgctac aagacggccc gctacaccgt
    10621 cgaacgcccc ctgcagctgg gcgtcgccct cgccggcggc ggcccgccgc tgctcgacgc
    10681 gtgctccgcg tacgggctgc ccgtaggcga ggcgttccag ctgcgggacg acgtgatcgg
    10741 cgtcttcggc gaccccgccg tcaccggcaa gtcctgtctg gacgacctgc gcgagggcaa
    10801 gcacacggcg ctgctcgccc tggcactcga atgcgccgac gccgcccagg cccgcaccct
    10861 gcgcgcgctg gtcggcgacc cggagctgga cgaggagggc gcggcgcgca tccgttccgt
    10921 actgctgtcc tccggcgccc tcgacaccgt cgagcacatg atcacggaac gccgccggcg
    10981 cgccctgcgc gccctggagc aggcgccgtt ccccgccgcc acgcgctccg ccctgcagca
    11041 actcgccgtc gacgcgaccg agaggacctc atgaccgccc acaccccgcc cgtgcccgcg
    11101 ccgtccggac gcgtcctgct ggccgcgccc cgcggctact gcgccggcgt cgaacgcgcc
    11161 gtggccgccg tggaacgcgc gctggagaag tacggcccgc ccgtctacgt acgcaagcag
    11221 atcgtccaca acacccacgt gatccggacg ctggaacgga agggcgccgt cttcgtcgag
    11281 gagacggacg acgtgcccga gggcggcacc gtgctgttct ccgcgcacgg cgtcgccccc
    11341 gaggtacacg aacaggccgc cgcgcgccgc ctgacggcga tcgacgccac ctgcccgctg
    11401 gtgacgaagg tgcaccggga ggcactgcgc ttcgccgagg agggctacga catcctcctc
    11461 atcgggcacg agggccacga ggaggtcatc ggcacgatgg gcgaggcgcc cgaccgcgtc
    11521 cagctcgtgg acggcccgga cgcggtggac ggcgtatgcg tacgggacga gcggcgcgtc
    11581 gtctggctgt cgcagacgac gctgtccgtg gacgagacca tggagaccgt cgaacgcctc
    11641 agggagcgct tcccggcgct cgtcagcccg cccagcgacg acatctgcta cgcgacgcag
    11701 aaccgccagc tcgccgtcag gcaactggcc gccgactgcg agctggtgat cgtcgtcggc
    11761 tcgcggaact cgtccaactc ggcccggctc gcggaggtcg cgctccaggc cggcgcggcc
    11821 gcctcgtacc tcgtggacag cgcacaggaa gcgcgggagg agtggctgcg cggggtgtcc
    11881 acggtcggtg tgacgagcgg cgcctccgtg ccggacgtcc tggtcgacga gctgctggtc
    11941 tggctcgccg gccgcggcta cgcggacgtc gggatcgtca cggcgacgga ggagcggcag
    12001 cggttcgcgc tgccgcgcga actggcccgc tcatgaccgt acttcgcccg ctcagcaccc
    12061 tgcccgtgac cgtacgcgca gccaggaggc gccgtggaaa ccgtgggcgt tgaccccgtg
    12121 gaactcgcag atccagtaga ccccgtacag cccgcgcagc ccccagactg tctcttatcc
    12181 accactgaga cgaggcgggc gagtgcagcg ccggcccctg cgtcatctcc atcgcgaagt
    12241 cgtccgccag ctccaggatc gtcgcgcgcc cctccagctc cgcgacccag cccggcggca
    12301 gcgccgtctc gccgttgatg gtgccgagca ggttgccgca gatcgagccg gtggcgccgc
    12361 tgtccccgcc gtgggtgacc ccgagcagca gcccgtgctg cacgtccccg gccaccagcg
    12421 cgcacgcgac cgctctcgac agggcctccc ccgccgtccc gccctgcggc cggtccctca
    12481 tgcccccccc ccgctgccac cgccctctcc cgccgccgcc tccaccccgt ccctctcccc
    12541 tatacactcc atctcccgcc cccgccaccc tcgccgccgg tcccgcctac ctccgcctcg
    12601 tccgcctcga agccgtgctc gccgagaccg tcgcccgcct ggacgccgac cgcaccgcga
    12661 ccgccgccgc cgggcccgcc acttccgccg gtgcgtccga cgggcgcgag tacggcccgg
    12721 gtgagcacac cgtgcgcgcc gtacggtgcg cgttctccga actcgccctg tccttcaccc
    12781 tcttcgggca ccaccggttc gagcaggccc tgcgcgccct gcccgcgcac accgcgctga
    12841 acgacctgcc gcccgactgc cccgagccgg accgcgccct ccccgggcac accgagtcgt
    12901 gcccgcactg ccgggagttc ctgcggctca accccgccta cgcgtgcctc ccgcagcgcc
    12961 gcgcacggct gctccaggac accgtggacc tcgccgtacg ggcccggctg gccctcgcgc
    13021 gcgcggcgct caccggaggg gacggcggcc tggaacgggc gtacgaggag tgggcggagg
    13081 cgatcgccgt ctccggccgg gcggcgatga ccgtacgcac caagatggcc gtcctgcgca
    13141 tggtcctcgg ccgtgccgac gcgctctccg acgaggacag cgtgcggcgc ggcagctgcc
    13201 tggacgaggc catcagcatc gtggaacgcg cgctcccgct gctcggcccg cccggacggc
    13261 agccgctgtc ggcgaagctg tccgaactgc tcgccgtacg gggcgtgtgg ggcggatacg
    13321 gctgcgccga gtacgacatc cgcccggaca tggtgcgggc ggaggcggat ctgcgccggg
    13381 cgctcgaact caacccggag tccgtgtacg cgcgcgacaa cctcgtacgg gtgctcgtct
    13441 tcggcctcga tccgcggccg ggcaccggca gcagggtgca caagctgacg gtgctgctgg
    13501 aggcgttccg gctgctgcac ggagggctgg aacggctgcc cacgcacgcc cgttactggg
    13561 agacgctggg cgacgccctc gaagacctcg agtcgctgct gctcggcggc ctctcctcgc
    13621 agcggctcct tgaccacctg gtgcaggtgc cggacgaggt ggagcgtgca cagggcgacg
    13681 cggcggcacg cgcccgcgaa ctcctggagg aggcgcggcg gctgcgcgac gcgcagggcg
    13741 acaccgccgg ggcgctgcac ctgctggcac gcgccacccg cgcgcacccc tcgaacgcgg
    13801 acgtgcgcct ggagctgctg cgcaccacgg agcagcggct gaacgaactg tgcgagccgg
    13861 gggcgtgatc ggtgcatgcg gtgtacgggg tgcgagcggc gcaggccgta cgcgagcgag
    13921 ctgggtgaga agacgaaggg tgagggactg tgttcaagga tccgctgacc gcgtggcacg
    13981 ggccgttccc gtacgacgtg ctggctccgg tgggggtgac acccgcgacg acgcactcgg
    14041 agatgcagga cgtgtcgttc gacctgatgg tgcagcgcct gatgaccccg gagacgcaga
    14101 ccgcgtggaa cgaactgcgc accctccaga agcggttgct ggtcgacgcc gtgctgtggg
    14161 acgtcgatcc ggaggcggag atcgccaccg cacggcagga gctggacgag gccctgagcg
    14221 acccggggga gccgcccgag gtggccgcgt gcctggcgcc gccgggagcg gacgcgctcg
    14281 actggctggt ggaggagctg gacggggtgg agctgaacgc ccccgaaccg gccctcccgg
    14341 acgaggcgga cgacgcgctg tccggtgcgc ccgtaccgcc gggcctgctc gacgagttga
    14401 tccggttcga ccgctgagcc ggtcgccgtg cacgggaagg gagggggtcc gcgctgatga
    14461 gtgagccgaa gacaccgcag ggcggcgggg ccgaactgga ccggctgcgc tgggagttcg
    14521 ccgccgcgct ggacgaacgc gaggcggcgc accgcgagca gacaggccgc ctgctgacgg
    14581 cgctcctcgg cgcgctcgac tcgttcgacc ggctgcttgc cgacggcccg ccgcccgcgg
    14641 acggcgaggg cgtgcaggcg taccaccaga gcgtagggct ggtagcccgg cagctggacg
    14701 aggccgtccg tacgggtggg ctggagccga tcgggctgcg cggtgagacg gcggacccgg
    14761 ccacccacca ggtgatcgac gtacgggagc cggggccgcc cggtacggcg gaggacgagg
    14821 tgctggaggt cgcacggcgc ggataccggt accacgggcg ggtgttgcgc gcggcgcagg
    14881 tggtggtcgc gggccccgcg cccgtacccg tacccgaatc cctgcccgca ccggaagcgg
    14941 accgcgaacc ggaacccgcg ccggaccgcg aaccggaacc cgaaccggag cccgcgccgg
    15001 accccggacc ggaaccggcc ccgtatacca atctgaccca gcgcacgaca gcctaggtgt
    15061 agaccgcgga gggggcggat cgattaagca aacacgtaaa cacacaacaa gaaatgctgc
    15121 aatgacacga cttcggcggt gtgcttgagc cccgctacat tatcggcgcg gaatcacttg
    15181 accagtgagc tattacgcac tctttcaagg atggctgctt ctaagccaac ctcctggttg
    15241 tctctgcgac tccacatcct ttcccactta gcacacgctt aggggcctta gtcgatgctc
    15301 tgggctgttt ccctctcgac catggagctt atcccccaca gtctcactgc cgcgctctca
    15361 cttaccggca ttcggagttt ggctaaggtc agtaacccgg taaggcccat cgcctatcca
    15421 gtgctctacc tccggcaaga aacacacgac gctgcaccta aatgcatttc ggggagaacc
    15481 agctatcacg gagtttgatt ggcctttcac ccctaaccac aggtcatccc ccaggttttc
    15541 aaccctggtg ggttcgggcc tccacgacct cttacagccg cttcaccctg cccatggcta
    15601 gatcactccg cttcgggtct tgaacacgct actaggccgc cctcttcgga ctcgctttcg
    15661 ctacggctcc cccacaacgg gttaacctcg caacatgccg caaactcgca ggctcattct
    15721 tcaaaaggca cgcagtcacg acacagaaag cacaaggctc cctgtgcgac gctcccacgg
    15781 cttgtaggca cacggtttca ggtactcttt cactcccctc ccggggtact tttcaccatt
    15841 ccctcacggt actatccgct atcggtcatc agggaatatt taggcttaac gggtggtccc
    15901 gccagattca cacaggattt ctcgggcccc atgctacttg ggtggctgtc caatgagtcg
    15961 agaatgtttc ggctacgggg gtcttaccct ctacgccagg cctttcgcat gcccttcgcc
    16021 tacacccacg atttatcact caccgaccgt ccggcagaac gatcaaaaca actcccacaa
    16081 ccccgcacgc gcaacccctg ccgggtatca cacacatacg gtttagcctc ctccggtttc
    16141 gctcgccact actcccggaa tcactattgt tttctcttcc tgcgggtact gagatgtttc
    16201 acttccccgc gttccctcca cacaccctat acattcaggt gcgggtgaca gcccatgacg
    16261 actgccgggt ttccccattc ggacaccccc ggatcacagc tcggttgaca gctccccggg
    16321 gcctatcgcg gcctcccacg tccttcatcg gttcctgatg ccaaggcatc caccgtgcgc
    16381 ccttaaaaac ttggccnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16441 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16501 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16561 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16621 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16681 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16741 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16801 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16861 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16921 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    16981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17101 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17161 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17221 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17281 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17341 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17521 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17581 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17641 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17701 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17761 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17821 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17881 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    17941 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18001 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn acagatgctc
    18241 gcgtccactg tgcagttctc aaacaacaac cagccacccg ccacccccaa cccacaagct
    18301 ggagtacacc gggaccggca cccaaagaaa ccaccgcaac aacggcccgt tccttcagac
    18361 acccaacagc gtgcccacca acacccaaac ccgacccccc accgctccac accccacaaa
    18421 agcagggccg tactaggcaa gagagccgac accaggtgcc ggtgaatagt caacgttcca
    18481 cccatgagca gaccaccgcc ggacatgcgc cgacgaaatg gtgctgtgct ccttagaaag
    18541 gaggtgatcc agccgcacct tccggtacgg ctaccttgtt acgacttcgt cccaatcgcc
    18601 agtcccacct tcgacgattc cctccccaag gggttgggcc accggcttcg ggtgttaccg
    18661 actttcgtga cgtgacgggc ggtgtgtaca aggcccggga acgtattcac cgcagcaatg
    18721 ctgatctgcg attactagcg actccgactt catggggtcg agttgcagac cccaatccga
    18781 actgagaccg gctttttgag attcgctccg ccttacggcc tcgcagctca ttgtaccggc
    18841 cattgtagca cgtgtgcagc ccaagacata aggggcatga tgacttgacg tcgtccccac
    18901 cttcctccga gttgaccccg gcagtctccc gtgagtcccc accaccccga agggcgtgct
    18961 ggcaacacag gataagggtt gcgctcgttg cgggacttaa cccaacatct cacgacacga
    19021 gctgacgaca gccatgcacc acctgtacac cggcccaaag ggagcccctg tctccaggag
    19081 tgtccggcat atgtcaagcc ttggtaaggt tcttcgcgtt gcgtcgaatt aagccacatg
    19141 ctccgccgct tgtgcgggcc cccgtcaatt cctttgagtt ttagccttgc ggccgtactc
    19201 cccaggcggg gaacttaatg cgttagctgc ggcacggacg acgtggaatg tcgcccacac
    19261 ctagttccca acgtttacgg cgtggactac cagggtatct aatcctgttc gctccccacg
    19321 ctttcgctcc tcagcgtcag tatcggccca gagatccgcc ttcgccaccg gtgttcctcc
    19381 tgatatctgc gcatttcacc gctacaccag gaattccgat ctcccctacc gaactctagc
    19441 gagcccgtat cgaatgcaga cccggggtta agccccgggc tttcacatcc gacgtgacac
    19501 gccgcctacg agctctttac gcccaataat tccggacaac gctcgcaccc tacgtattac
    19561 cgcggctgct ggcacgtagt tagccggtgc ttcttctgca ggtaccgtca ccgataaaag
    19621 cttcttccct gctgaaagag gtttacaacc cgaaggccgt catccctcac gcggcgtcgc
    19681 tgcatcaggc ttccgcccat tgtgcaatat tccccactgc tgcctcccgt aggagtctgg
    19741 gccgtgtctc agtcccagtg tggccggtcg ccctctcagg ccggctaccc gtcgtcgcct
    19801 tggtaggcca tcaccccacc aacaagctga taggccgcgg gctcatcctg caccactaac
    19861 gctttccacg ggccggggtc gcgccaggcg gcgcggcagg cggctcagcc ggaggcggcg
    19921 gggctaccgg cacgggagcc tcgggcgccc ctggcgccgg gaccgcccca ggcggcggcg
    19981 gtggtggtgc ctgcgtcccc gcgcgtgcct gttcttcacg cgcccgttcc gcacgtgcct
    20041 gctctccacg cgcctcctcc gcacgtgcca gctccgaagg tgacgtcccg gtcggcgccg
    20101 gaggcggggc cgggaggtcg gccagaggct ggttcggcag caggccgttg ttcaccggcc
    20161 cggggacata cgggggcggg ccgttctctt ggccgggtgg tttggcgaca cccgcggaga
    20221 cctcgccccg agtgggctgg aacgcggggt tgagcgggtc ctgcgagggg tccggcggaa
    20281 ttccgccgtc catctcgcgt atggccctct tgtactccgg ggaggcgtgc tcgtcggtgt
    20341 acgcactcgc gttccacagg gcgcccagga gagcggtggc gggcggaacc gctttgagca
    20401 tccctttcga cgccttcttc gcagcgtctt ctacttcgcc ctctggtttg ggaatcggcc
    20461 gggcgttttc cgggtccctg agaccctcag cagcggtcac cagctgatca ggcgtgacga
    20521 agccggtgta ggcaccgtcg aacgtgcgcc ccatgaagtc gccccagttc cactcgggag
    20581 tgggagcggg ctcgttcgcg cgggaccgag tgtcctcctc aggtgccggg gcctgcgccg
    20641 ggggaggcgc aggatccgga gcaccctcag gtggcggcgc ggcctcggcc gggggcgcgt
    20701 tctggcccgc accgggttcc ggggcagcgg ccggcggcgc ctcctcggag gcatcgggag
    20761 catcgggagc atcggagtcc gcagagtcct cggccgcgtc ctcggcctgc tgctgttcct
    20821 gctccggctg cggctgctcc gtctgttcct gccgcaccgt ctcggtctgc gcctgcgcct
    20881 gcgcctgccc cggcacaacg gccgccggca gcagccacgc accgaccccc agcgctcccg
    20941 ccaccgcagc cgtacggacc aactgccggt tccacagcgg cttctcctgc caccccggcc
    21001 tcggcgtgga gaacgccgac tctgccgcct ccgacggccg agagccgtcc ccggcaccga
    21061 ccgtgtccgc cacg
//
