LOCUS       NZ_CP031320            26022 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces armeniacus strain ATCC 15676 chromosome.
ACCESSION   NZ_CP031320
VERSION     NZ_CP031320.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces armeniacus
  ORGANISM  Streptomyces armeniacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Draft genome of the type strain Streptomyces armeniacus ATCC 15676
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2018) Department Of Chemistry and Biomolecular
            Sciences, University Of Ottawa, D'Iorio Hall, 10 Marie Curie,
            Ottawa, Ontario K1N 6N5, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUL-2018
            Assembly Method                   :: SPAdes v. JULY-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003355155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:13:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,031
            CDSs (total)                      :: 6,963
            Genes (coding)                    :: 6,742
            CDSs (with protein)               :: 6,742
            Genes (RNA)                       :: 68
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 36 of 221
            Pseudo Genes (incomplete)         :: 204 of 221
            Pseudo Genes (internal stop)      :: 5 of 221
            Pseudo Genes (multiple problems)  :: 22 of 221
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:36:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7573866
            Orig. end                         :: 7599888
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031320.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26022
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /region_number="36"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /tool="antismash"
     cand_cluster    1..26022
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /kind="single"
                     /product="azole-containing-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26022
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16022]"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16022
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            complement(44..1144)
                     /gene="galT"
                     /locus_tag="DVA86_RS32890"
                     /old_locus_tag="DVA86_33105"
     CDS             complement(44..1144)
                     /EC_number="2.7.7.12"
                     /GO_function="GO:0008108 - UDP-glucose:hexose-1-phosphate
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="galT"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014054418.1"
                     /locus_tag="DVA86_RS32890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33105"
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="WP_208883776.1"
                     /transl_table=11
                     /translation="MKKTSNRLADGREIVYYDASDDAVREAADQRPLEPTATASEIRYD
                     PLLAEWTAVTAHRQARTYHPPADECPLCPSRDGRLSEIPEPDYDVAVFENRFPSFTGGP
                     GPETAGGPHGLFASAPGAGRCEVVCFTSDHTASFADLTEPQARLVLDVWTDRTAELSQL
                     AGVEQVFCFENRGREIGVTLGHPHGQIYAYPFTTPRTERMLRTAAAHRDRTGGRNLFDD
                     VLDAELADGQRVVLEGEHWVAFVPHAAHWPYEVHLYPRRRVPDLLGLEEEQRAEFPRIY
                     LEVLRRFDRIFGPGEPPTPYIAAWHQVTGAVPERREFALHLELFTIRRTSGKLKFLAGS
                     ESGMNVFINDVPPEAAAERLREVASE"
     misc_feature    1129..1144
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.39"
                     /tool="antismash"
     misc_feature    1308..1322
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.76"
                     /tool="antismash"
     gene            1379..3049
                     /locus_tag="DVA86_RS32895"
                     /old_locus_tag="DVA86_33110"
     CDS             1379..3049
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950275.1"
                     /locus_tag="DVA86_RS32895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33110"
                     /product="sodium:solute symporter family protein"
                     /protein_id="WP_208883777.1"
                     /transl_table=11
                     /translation="MTNLAEGLRLHTNALDYTLLAIYFVVVLGIGFAARRSVKTSLDFF
                     LSGRSLPAWITGLAFVAANLGATEILGMAANGAQYGVYTVHWYWVGAIPAMVFLGLVMM
                     PFYYGSKVRSVPEFLLHRFGPSSHLLSSVIFAVSAVLIAGVNLYAMAIVLEALLGWPQW
                     VAIVVAGFFVLAYITLGGLSSAIYNEVLQFFVILAALIPLTVVGLKRVGGWGGLSDSLT
                     DSKSEAFMTAWDGTGIGSANPLGANWLTIVLGLGFVMSFGYWTTNFAEVQRALSAKNLS
                     AGKRTPLIAAFPKIMIPMVVVVPGLIALVMEPTIGTKEDGLQYNDAIPVLMRDLLPNGV
                     LGVAVTGLLAAFMAGMAANISSFNTVFTNDIWAPYVKKDQPDAHYVLTARVVTVIGVLI
                     GMGTAFIASTFSNIMNYLQTLFSFFNVPLFVVFIIGMFWKRTTPAAGFWGLLSGTVAAM
                     INYFWFYKEGVIDIPSDQGANFVSSIVAFVVGSVVMVVVTLVTKPKPVEQLAGLVYGTV
                     SPGMEEPPAEGDDAWYRKPALLGWGAIILAAACYVPFSF"
     gene            3185..3481
                     /locus_tag="DVA86_RS32900"
                     /old_locus_tag="DVA86_33115"
     CDS             3185..3481
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091079.1"
                     /locus_tag="DVA86_RS32900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33115"
                     /product="hypothetical protein"
                     /protein_id="WP_208885496.1"
                     /transl_table=11
                     /translation="MHEVEELERESSTAARLFDVRRIIGGLFVVYGVIVTIAGIFASEE
                     DLKKAQDININLWTGLGMLALGIFFLVWLRLSPAVPPPPPEEADTAGGDPLLK"
     gene            complement(3563..4246)
                     /locus_tag="DVA86_RS32905"
                     /old_locus_tag="DVA86_33120"
     CDS             complement(3563..4246)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326451.1"
                     /locus_tag="DVA86_RS32905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33120"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_208883778.1"
                     /transl_table=11
                     /translation="MSVRLMVVDDHRLLAEALASALKLRGHRVLAAAAPSAGAAELVLS
                     RAPEVCLLGTATPAAPGIFDPVLRIKREKPQIAVVVLGPVPSPRGIAAAFAAGASGYVR
                     NDERIEGVERAMMKARAGEVAVGPQLLRDAFTELLNPAAEPDDEGQRLLQMLTPREVEV
                     LVRVAEGEDTRLIAAGMRIAPSTARTHVQRVLMKLDVGSRLEAAALAARTGLLDRATGP
                     YARGE"
     gene            complement(4454..6187)
                     /locus_tag="DVA86_RS32910"
                     /old_locus_tag="DVA86_33125"
     CDS             complement(4454..6187)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019549643.1"
                     /locus_tag="DVA86_RS32910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33125"
                     /product="PQQ-binding-like beta-propeller repeat protein"
                     /protein_id="WP_208883780.1"
                     /transl_table=11
                     /translation="MSQPPPPPSQPPSGGFGAPQDPPPGPQGGQNGGYGYPQDPGQTPG
                     YGYPQQPPGPPPGGGFGAPTPPPPGGYGQPQGQPPYGQPQYGQDPGGYPTTPGGPGFPG
                     GPGGPGGPGGGNSKLAVIIAVAVAVVLIAGGAVFFLTKDDDGGKDDESKGDKKGSSEGA
                     TGGGGGGGGDKKPTNLNAKLLAKMEAPAVDDQVSVPGAWVTEKVFVKTSVESVVAHDGK
                     SGAKAWEIPLSGSVCAASPHQTEDNKTAIVTQETKSSKADCNQMVVIDMETGKKVWQET
                     MPGADTISVENVTISQGTVASAWIGGSVGFKITGGKPIWQAKPSGDCKDEGYAGGPKLL
                     AVVKCGDLDKPDFTIQELDPKTGKSVSEFEVPKGTETVRIPSTAPLVLVVGAGDSTPTD
                     IMTVANNKLAAKISLGGDRYNNPCGLDVESCFGMTVGKDAVYLSTKEHDDSSSDYGQTN
                     EVMAFDFTTGKTKWKSDAGAKRTIMPIQMEGENVIGYKLPTYDSGGEIVAIEPKAGKQT
                     PYLKLPNDSVDEEQELGPNTYGQDTEVVYGNGKLLLPEKYVTDRAGTFTKERLLAVGFG
                     G"
     gene            complement(6505..8382)
                     /locus_tag="DVA86_RS32915"
                     /old_locus_tag="DVA86_33130"
     CDS             complement(6505..8382)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643767.1"
                     /locus_tag="DVA86_RS32915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33130"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_208883781.1"
                     /transl_table=11
                     /translation="MAVNLVNLEAVGKVYGTRALLDGLSLGVSEGDRIGVVGRNGDGKT
                     TLIRILAKRETADEGRVTHAGGLRLGVLTQHDSLDPEATVRHEVVGDMADHEWAGSAKV
                     RDVLTGLFGGLDLPGFPEGMDTVIGPLSGGERRRIALAKLLIAEQDLIVLDEPTNHLDV
                     EGIAWLAGHLRARRSALVCVTHDRWFLDQVCTRMWDVQGGTVHEYDGGYSDYVFARAER
                     ERIAATEEARRQNLMRKELAWLRRGAPARTSKPRFRIEAANELIADVPPPRDSAELMRF
                     AGSRLGKTVFDLEDVTVQAGRKVLLRQLTWQLGPGDRIGLVGVNGAGKTSLLRALEEAA
                     RSEGERQPAGGRIKVGRTVRLAYLSQEVAELDPSWRVLEAVEQVRSRVDLGKGREMTAS
                     QLCERFGFGKQRQWTPVGDLSGGERRRLQILRLLMDEPNVLFLDEPTNDLDIETLTQLE
                     DVLDGWPGSLVVISHDRFFLERTTDRVHALMGDGTLRMLPRGVEEYLERRARMRAADQP
                     AAPVAAPAAAAPQAGGSGGATGTSGTSGTAGGGERPKGAGLSRAAQKELQRIERQLDRI
                     GDKEKQLHADIADNATDFARVAELDARLRELTTERDNLETRWLELAEDG"
     gene            complement(8411..>8890)
                     /locus_tag="DVA86_RS32920"
                     /old_locus_tag="DVA86_33135"
                     /pseudo=""
     CDS             complement(8411..>8890)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="DVA86_RS32920"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33135"
                     /product="cytochrome P450"
                     /pseudo=""
                     /sec_met_domain="p450 (E-value: 2.9e-06, bitscore: 24.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="SDAEELDVTRSARQHVGFGFGIRQCLGQHLARATLRIGLSKLFDR
                     VPTLRLAVDPSEVPLRERAAHYGCFCRLHGHRRDLLLRLRRKHQMGIRDSPQPVRRLRT
                     ALGHAVAAPGTARCRSRPSARRATGGPRRPVNRRREGPAAGPPAAARPETPRPVP"
     misc_feature    complement(8923..8934)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(8927..8940)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     gene            complement(9112..9852)
                     /locus_tag="DVA86_RS32925"
                     /old_locus_tag="DVA86_33140"
     CDS             complement(9112..9852)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266076.1"
                     /locus_tag="DVA86_RS32925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33140"
                     /product="hypothetical protein"
                     /protein_id="WP_245997453.1"
                     /transl_table=11
                     /translation="MTSSAARPDCDRTPADRTAPAPSPAPGPAPAPAAERARVRARARV
                     VLLTGPSGSGKTRLAARAGLPVLRLDDFYKEGGDPTLPQLPGGATDWDAPGSWDADAAV
                     AAVRELCEHGRTTVPLYDIAASARTGEEALTLGGAPLFVAEGIFAADIAARCAELSLLA
                     DAICLRGRPLTTFRRRLLRDVREGRKSVPFLVRRGWGLMRSEGAIVARHTTLGAYPCAR
                     DEALGRIAGLHERERAEAGVRGGH"
     gene            complement(10001..10795)
                     /locus_tag="DVA86_RS32930"
                     /old_locus_tag="DVA86_33145"
     CDS             complement(10001..10795)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF00881"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013077.4"
                     /locus_tag="DVA86_RS32930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33145"
                     /product="SagB/ThcOx family dehydrogenase"
                     /protein_id="WP_208883783.1"
                     /sec_met_domain="PF00881 (E-value: 9.2e-20, bitscore: 70.0,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAQPDGSPVSDPRAYAPLAAELHENSKFSRDRQANFAEPVQRFE
                     TDLDRLRGGGDRFGKASAVVLDDEPLPLAPLGELAARRRSHHGTWGDTPLTRRSLATIL
                     RVGVGTTGMHRPAPSAGGRYPVECFVAVTDVDGLDPGIYYYAPHALELRRIDPDDPAAA
                     LRKSCMQPEDLEGAGAVVVLTGVFSRSTSKYAERGYRFTLLEAGHIGQGICLSAEGVSA
                     GSLCLSGFYDHELDGLLRLDERVESVVHSIVLGAAGERPAGS"
     gene            complement(10864..12207)
                     /locus_tag="DVA86_RS32935"
                     /old_locus_tag="DVA86_33150"
     CDS             complement(10864..12207)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="DVA86_RS32935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33150"
                     /product="YcaO-like family protein"
                     /protein_id="WP_208883785.1"
                     /sec_met_domain="YcaO (E-value: 3.1e-56, bitscore: 190.1,
                     seeds: 127, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR03604 (E-value: 6.4e-71, bitscore:
                     237.8, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDVTAAPPVPRARAGVDTAAVVSPRTGIIRQLVPFVSELLPRT
                     TVARLAPAARPEVLPGVPKDYGVTGFGIGTSLAEARSAAVGETVERYGSLVGAAHARVE
                     WGTFDEFEGDAVHGESFVLPHPKESSWTAFDEKAPRGWVVGHDLTEDRRVLVPAQLALP
                     SYKSRFEGEELAPWTTNGLAAHTDPSAAVLAGLREIEERDAFTIRHLNRWTPPEIPFAG
                     ICDDVDGFVASAPRWHAMTVRAWDLTLDLGQPVVLAGVLTRSDRVPPFCFGAACRGDYP
                     SALRKAVLEAFQISAVMSRRGYPDRAEPGPMEDLAEPEEHIRMSCLPGYRDTLDWLLDD
                     HADWNPPDTSNTSDTSDTSAGCTTLDAAVDAVARRGMRVITVDLTPPDLRGLGWHVCKV
                     LVPGAQPLDFGALQSRTGRRLYDLPVELGYRREPAREDELNPAPHFFA"
     gene            complement(12197..13063)
                     /locus_tag="DVA86_RS32940"
                     /old_locus_tag="DVA86_33155"
     CDS             complement(12197..13063)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR03882.1"
                     /locus_tag="DVA86_RS32940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33155"
                     /product="TOMM precursor leader peptide-binding protein"
                     /protein_id="WP_222623393.1"
                     /transl_table=11
                     /translation="MTGDVALRGRTAGLARRVLCAVERPSSVGAVAREVDAPAEKVARL
                     LARLESQGLVTTLAELDKGPGADREANAALRLFADEGLSDAVTADGARAEIVCLGDEEL
                     GARFAELTSASLGVRLSRRPVLDEADAPALSGEAPSFVVSLARDRDEEHLRRLDRWSRR
                     AGVPYLAGWFEGVTVVLTHVVVPRRTACYDCLCVRERAAAPGPGESGGTEASAGGPPLA
                     FAPAGRLAAGDGLLTSLASLRAVNVFAGHANEAPAPVLLQLSFTTLKLTRHPVLRVPMC
                     ESCGHAQ"
     misc_feature    13142..13152
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    13304..13321
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.62"
                     /tool="antismash"
     misc_feature    13319..13333
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.83"
                     /tool="antismash"
     misc_feature    13323..13332
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    complement(13331..13342)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 18.25"
                     /tool="antismash"
     gene            13366..13554
                     /locus_tag="DVA86_RS32945"
     CDS             13366..13554
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVA86_RS32945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_208883787.1"
                     /transl_table=11
                     /translation="MTPEQQTPGIAPDSSVDTDPMDTIDLTIEKLGPRLALDNTEGGSS
                     ATTGSCTLSGTMCGGRG"
     gene            13608..16022
                     /locus_tag="DVA86_RS32950"
                     /old_locus_tag="DVA86_33165"
     CDS             13608..16022
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: TIGR03604"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03604.1"
                     /locus_tag="DVA86_RS32950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33165"
                     /product="YcaO-like family protein"
                     /protein_id="WP_208883790.1"
                     /sec_met_domain="TIGR03604 (E-value: 4e-66, bitscore:
                     222.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="YcaO (E-value: 3.4e-55, bitscore: 186.7,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQATPDAVESAEGTQLLPRSDNRILVRGWNHGAELAGGHASLAG
                     RLLAAARGGCTPGELAALTGVPFVRVQALVERLLEQGLLEPSPLRRGPAAPLPAARALG
                     AATEPGSVLDAVVTDDPALAEHLTAELRHRPGTPDFVVTGNAAELARRADGRAVNAVLP
                     RHLVERDDDPAVRGVLTTGGRWACYWREHGRTVVTSDLSCSGPGYGLCLACLRLRERAG
                     ARSPRRGGDDGHRTVYAPGNVYAPPTAALLAHVLAGLRAGPPAAAGGAVLYELHHDRVR
                     LSRVRGLPVCPACTPLAGGPYGDLLLTSPPRSLSPPETPAVHAARPDGAVRPPAAAPED
                     ALSLEQITDRCRRSSDLPAPELAALLRDLGELYGRRGTVLRAIRPEVPAVAADCFHAVA
                     ADLADLRRISASNGQPQAYDAFGGAWTAAGAVQRCLGEAVERYCALVHGAARRVVWGAA
                     DELPDAVPVERFATLSPAELRDSGRDLRPASSRSRLGWVEGHSLTRARPVLVPAQLSFL
                     AYTAAASEDAVQPGSNKGLAAGRSADRCVVHGLCELVEADALLIHFLNRSPVPEIGLGD
                     TGIPRVDRVHRAVRAAGGRLRAWDFATDLAVPTVLVMLERHDGTGPVATFGMATRPDPA
                     NALEKAVLEALHATCWLTGEMAEAARAFPGVPTPEWVTAREQAKSLGASSAYLASLGWL
                     LDREVRRPFREYAAGYPEVAHDPAAQRHGLVGALAAAGLEPVAVDLSTPDVRDATGLEV
                     WRSIVPGLQPFSIGTLQARAGDRLFSVPVRMGYRSAPAAESDLNPLPHPCP"
     gene            16118..17281
                     /locus_tag="DVA86_RS32955"
                     /old_locus_tag="DVA86_33170"
     CDS             16118..17281
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVA86_RS32955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DVA86_33170"
                     /product="hypothetical protein"
                     /protein_id="WP_208883791.1"
                     /transl_table=11
                     /translation="MLSREFAPERPKLAEPVEATVDGDQAYVRIGTPPSYIRLGAPAWS
                     ITRLLDGSRSVREVAHEAGCTEEQVRRLADQLGGGGLLEGSEAQQERHDSDVHRQSVFF
                     LKFTWHDPRALGTVYDVVRRWIPPRWFAALAATLCVAGAAACLLSWTSMISQAQEAVSW
                     SQVWQVWPAILLRAVVHELGHAFFCLSFGRSVAALGFGLYYFQPVAFTDVSDIWLLRRR
                     WQRVLVHLGGPIVDVALLVASGVTVLAASDGLVETFAAYLLLSTLVGAAAGFNPLLRSD
                     GYFVLTELLREDDLRDRALVLMATTAPWRLSVRDRTSAVLVTYGAVSFVYTLVIVGIGA
                     NVASRFVLHTVLGFDALPQAVMWSLGAGIALVLWTVMLRRARNATLA"
     misc_feature    complement(16155..16169)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(17294..18103)
                     /locus_tag="DVA86_RS32960"
                     /old_locus_tag="DVA86_33175"
     CDS             complement(17294..18103)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018562409.1"
                     /locus_tag="DVA86_RS32960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33175"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_208883792.1"
                     /transl_table=11
                     /translation="MDAVFKALGDASRRRLLDRLNVRNGQSLRELCEGLDMTRQAVSKH
                     LAVLEAARLVVVVRQGREKLHYLNPVPIHELADRWIGQYERGRLDALSALKRSLEGSTP
                     MSSAKFVYVTYIQTTPEKLYEALTKPEFTKVYFSDTGPQSTWEVGSPVRWKSDPAGEFE
                     ELGQRVLAAEPGKRLSYTWHTLQPMHQEMLGMSDEEFEEARKERSQVTFEIEPAEEASL
                     GVKLTIIHDGFDSADSKMLASVSGGWVMILSALKTMLEGGKTVAEQE"
     misc_feature    complement(18088..18102)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     gene            18314..18751
                     /locus_tag="DVA86_RS32965"
                     /old_locus_tag="DVA86_33180"
     CDS             18314..18751
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550432.1"
                     /locus_tag="DVA86_RS32965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33180"
                     /product="hypothetical protein"
                     /protein_id="WP_208883794.1"
                     /transl_table=11
                     /translation="MSSRPRHARTKQPRRSRALLRAGLTVTAAGAAVMAGSGMASADTR
                     ITGEETGLPIGSIETDALEDPSGVLKRQLEGGLSGSLGPAKDLPLYPLAGTAVDPLANS
                     VGAQVADFQTVSTEAVTGPLASGSTLRELPVLGQVATALPG"
     gene            complement(18801..>19310)
                     /locus_tag="DVA86_RS32970"
                     /old_locus_tag="DVA86_33185"
                     /pseudo=""
     CDS             complement(18801..>19310)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005486356.1"
                     /locus_tag="DVA86_RS32970"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="DVA86_33185"
                     /product="NUDIX domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRTPRRAARIAVLDPQGAIFLFRYDNEEVGVHWAMPGGGLEPGET
                     P"
     assembly_gap    19470..19516
                     /estimated_length=47
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(19631..19867)
                     /locus_tag="DVA86_RS32975"
                     /old_locus_tag="DVA86_33190"
     CDS             complement(19631..19867)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058107.1"
                     /locus_tag="DVA86_RS32975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33190"
                     /product="hypothetical protein"
                     /protein_id="WP_208883795.1"
                     /transl_table=11
                     /translation="MSTEPAEEPDGRGARIPRDPPDQQAGAAGETPDEELVPGGEEEDA
                     ELPDTDETGSGPRGTPQTEYEHPDRPEPYESTD"
     misc_feature    complement(19928..19946)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.86"
                     /tool="antismash"
     gene            20238..>21275
                     /locus_tag="DVA86_RS32980"
                     /old_locus_tag="DVA86_33195"
                     /pseudo=""
     CDS             20238..>21275
                     /GO_function="GO:0042834 - peptidoglycan binding [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384512.1"
                     /locus_tag="DVA86_RS32980"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33195"
                     /product="peptidoglycan recognition family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAVLCGTAAAAAITLTVQPATATNAPEGDSMADAFTDAAEEYDVP
                     RDLLVAVGYGETHLDGHNGEPSQDNGFGVMHLVSNPDRDSLGRASKITGESETDLKRET
                     RANILGGAAVLRAHADALGLDAAERDELGKWYPAVARYGGAENKQLAKFYADSAYEILA
                     DGVRGGTDGGDRVRTRARDVAPDRGGYADVPDLGTRSPDYPPALWVPAHEANYAAGRSA
                     AISQVVVHVTQGSYAGSISWFQNPEAEVSAHYVIRSADGEITQMVRDGDTAWHARDANS
                     SALGIEHEGFIDDPSWFTDAMYRSSAALTKHLCDTHGIPKDREHIVGHSEVPGNDHTDP
                     GPNWNW"
     gene            21398..21811
                     /locus_tag="DVA86_RS32985"
                     /old_locus_tag="DVA86_33200"
     CDS             21398..21811
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018844316.1"
                     /locus_tag="DVA86_RS32985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33200"
                     /product="HIT domain-containing protein"
                     /protein_id="WP_222623394.1"
                     /transl_table=11
                     /translation="MNCTFCAIVAGETPSHRVYEDERAVAFLDTRPLFPGHVLVVPRRH
                     AETLTDLPDSDVGPFFGRVQRITGAVERAMEAAGSFVAANNRVSQSVPHFHVHVVPRNR
                     KDGLRGFFWPRGRYTDDAHAEDVAARLRAALED"
     gene            21855..23591
                     /gene="polX"
                     /locus_tag="DVA86_RS32990"
                     /old_locus_tag="DVA86_33205"
     CDS             21855..23591
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003887 - DNA-directed DNA polymerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /codon_start=1
                     /gene="polX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018546331.1"
                     /locus_tag="DVA86_RS32990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33205"
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="WP_208883798.1"
                     /transl_table=11
                     /translation="MARPNEDVRALLQEYAELLLITGKDAYKARAYEKAARAIGGCHAD
                     VSTLDAKGLREIPGVGKSIADKVVEYLRTGSMPAVEEERARIPAGVRRLMEIPALGPKK
                     ALTLYEELGVSSVGELREAVEQERLRDLKGFGPRSEENILHGIGLLEASGERIPVHAAT
                     ELAEEIVAALSAVPGCVDCAWAGSLRRMRETVGDVDVLVAARRSEPFMEAFTALPFVAE
                     VIARGEKKTSVRTAKGTQVDLRVVPPDSWGAALLYFTGSKAHNIRIREMAVRGKLKLSE
                     YGLFHTESGRKIVSRTEEKVYSRLGLPWIPPPLREDRGEIAAGLRDELPQLITERDIRG
                     DLHTHTDLTDGLAPLEDMVAAAAERGLRYYAVTDHAPDLHMQRMTRDKMLAQRERVRAL
                     DRTHRGLRLLHGTELNIGPDGEVDWPPEFLADFDVCVASVHSHFGLDRDAQTRRLLAAC
                     EHPYVHVIGHPTTRILGKRQSMDADWDAVFAACARTGTALEVNAHPNRLDLTDELVLRA
                     RDHGVKFAVDTDAHSVPDLGYLRYGVGVAQRGWLTPEDVITTWPLTRLRHFLRKRAGTR
                     AR"
     gene            complement(23688..23831)
                     /locus_tag="DVA86_RS32995"
     CDS             complement(23688..23831)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240744.1"
                     /locus_tag="DVA86_RS32995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_208883800.1"
                     /transl_table=11
                     /translation="MPGLIARIKEFTRSPQGQKAINSARQAARDPKKQAQARKLLGKLR
                     KR"
     gene            complement(23970..25349)
                     /locus_tag="DVA86_RS33000"
                     /old_locus_tag="DVA86_33210"
     CDS             complement(23970..25349)
                     /GO_function="GO:0000166 - nucleotide binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359095.1"
                     /locus_tag="DVA86_RS33000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_33210"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_208883801.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 2e-15, bitscore:
                     56.2, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDQGISRRSVLHTTGAAGAALGIGALGTTSAEAAAATGTDAPPR
                     SAPTMVGVPFEPRSAVRVALVGLGNRGAGMLELFLTLKGVRVVALCDSVRDKAAAAAEK
                     VTKAGQPAPALYTKGERDYENLCRRGDIDLVYIATPWEWHHPMAKSALSNGKHTGVECP
                     LAMTLEQLWELVDLSERSRRHCMQLENCAYGRNEMRVLRMAHAGLFGDLLHGAGAYLHD
                     LRELMFDPEYYEGPWRRKWHTRLKGDLYPNHGFGPVANYMDLNRGDRAVRISSVGSPAL
                     GLAAYRKEHMPPGDESWKESYVSADLSVSLVQTAKGRVIRLEHDVSNPRPYSRINTLGG
                     TRGVFEDYPPRIYLEPDRDDHEWGDFEDYASWDHWLWKEHPDPPGGHDGMDYLMLYRLV
                     QCMRLGLTPDFDVYDAATWTAPVPLSHASIRAHGAPQDFPDFTRGHWRTPRPGTDSPRP
                     D"
ORIGIN
        1 cgtacggcgg ccggtcccgt gctggtcccg ttcccggttg tactcactcg ctcgctacct
       61 ctcgcagtcg ctcggccgcg gcttccggcg gcacgtcgtt gatgaacacg ttcatgccgg
      121 actcggaacc cgcgaggaac ttcagcttgc cggaagtgcg gcgaatggtg aaaagctcaa
      181 ggtggagcgc gaactcgcgg cgctccggca cggcgcccgt gacctggtgc caggcggcga
      241 tgtacggcgt cgggggctca cccggtccga agatccggtc gaagcggcgc agcacctcga
      301 ggtagatgcg ggggaactcc gcccgctgct cctcctccag cccgagcagg tccggcacgc
      361 ggcggcgcgg gtagaggtgc acctcgtacg gccagtgcgc ggcgtgcggc acgaacgcca
      421 cccagtgctc gccctcgagc acgacgcgct gcccgtctgc cagttcggcg tcgaggacgt
      481 cgtcgaagag gttgcggccg cccgtacggt cccggtgcgc ggcggccgta cgcagcatgc
      541 gctcggtgcg cggggtggtg aacggatagg cgtagatctg gccgtgcggg tgcccgaggg
      601 tgacgccgat ctcgcggcct ctgttctcga agcagaacac ctgctccaca ccggccagtt
      661 gggacagctc ggccgtgcgg tcggtccaca cgtcgaggac gaggcgggcc tgcggctcgg
      721 tgaggtccgc gaacgaggcg gtgtggtcgg aggtgaagca gacgacctcg cagcggcccg
      781 cgccgggcgc ggaggcgaac agtccgtggg gcccgccggc ggtctcgggg ccggggccgc
      841 cggtgaagga ggggaagcgg ttctcgaaca cggcgacgtc gtagtcgggt tcggggatct
      901 cgctgaggcg cccgtcccga gaggggcaca gggggcactc gtcggcgggc gggtggtacg
      961 tgcgggcctg gcggtgcgcg gtgacggcgg tccactcggc gagcagcggg tcgtagcgga
     1021 tctccgaggc cgtcgccgtg ggctcgagcg ggcgctggtc ggcggcctcg cgtacggcgt
     1081 cgtcactcgc gtcgtagtag acgatctcgc ggccgtcggc gagccggttc gaggtcttct
     1141 tcacggacgc tcctcaccca accaccaaac agaagtcaac ataatgaagc acaactcaac
     1201 agggaggtca agcgcgcgtt gacttagcca gcaaaagcga catcgcgcac aatcgctcca
     1261 ccgtaacgcc cgatctccct cacaaccaaa caaaacccag caacttctct cttcagaaag
     1321 tgatggcaaa cgagtacctt cacgtccgtt ccctctgaac tatgaagcga gtgaccgtat
     1381 gaccaacctc gccgaagggc ttcggctcca caccaacgca cttgattaca cacttctggc
     1441 catctacttc gtcgtcgtcc tcgggatcgg cttcgcggcg cgccgcagcg tgaagacgag
     1501 tctcgacttc tttctctccg gccggtcgct ccccgcgtgg atcaccggcc tcgcgttcgt
     1561 cgccgccaac ctcggggcca ccgagatcct cggcatggcg gccaacggcg cacagtacgg
     1621 cgtctacacc gtccactggt actgggtggg cgcgatcccg gccatggtct tcctcggcct
     1681 ggtgatgatg ccgttctact acggctcgaa ggtccgctcc gtaccggagt tcctgctgca
     1741 ccgcttcggg ccgtcgtcgc acctgctgag ctccgtgatc ttcgcggtct ccgcggtcct
     1801 gatcgccggc gtgaacctgt acgccatggc gatcgtcctg gaggccctgc tgggctggcc
     1861 gcagtgggtc gcgatcgtcg tcgcgggctt cttcgtgctc gcgtacatca cgctcggcgg
     1921 cctctcctcg gcgatctaca acgaggtgct ccagttcttc gtcatcctcg ccgcgctgat
     1981 cccgctgacc gtcgtcgggc tcaagcgcgt cggcggctgg ggcggcctca gcgactcgct
     2041 cacggactcc aagagcgagg cgttcatgac cgcctgggac ggcacgggca tcggctcggc
     2101 caacccgctg ggcgccaact ggctgaccat cgtgctcggt ctcggcttcg tgatgagctt
     2161 cggctactgg acgaccaact tcgcggaggt gcagcgcgcg ctgtccgcga agaacctgtc
     2221 ggcgggcaag cggacaccgc tgatcgccgc gttcccgaag atcatgattc cgatggtggt
     2281 cgtcgtcccc gggctgatcg cgctcgtgat ggagccgacg atcggcacca aggaggacgg
     2341 actccagtac aacgacgcca tcccggtgct gatgcgggac ctgctgccga acggtgtgct
     2401 gggcgtcgcc gtcaccggtc tgctggcggc gttcatggcg ggcatggcgg cgaacatctc
     2461 gtcgttcaac accgtgttca cgaacgacat ctgggcgccg tacgtgaaga aggaccagcc
     2521 cgacgcgcac tacgtgctga cggcccgcgt ggtcaccgtg atcggcgtgc tgatcgggat
     2581 ggggaccgcg ttcatcgcgt ccacgttcag caacatcatg aactacctcc agaccctgtt
     2641 ctccttcttc aacgtgccgc tgttcgtggt cttcatcatc gggatgttct ggaagcggac
     2701 gactccggca gccggtttct gggggctgct gtcgggcacc gtggccgcga tgatcaacta
     2761 cttctggttc tacaaggaag gcgtcatcga catccccagc gaccagggcg ccaacttcgt
     2821 gtcctccatc gtcgccttcg tcgtgggctc cgtggtgatg gtcgtcgtca ccctggtgac
     2881 caagccgaaa ccggtggaac agctggcggg actggtctac ggcaccgtct cccccggcat
     2941 ggaggaaccg ccggccgagg gcgacgacgc ctggtaccgc aagcccgcac tgctgggctg
     3001 gggcgcgatc atcctcgccg ccgcctgcta tgtccccttc tccttctgat ccgcgaaggg
     3061 ctgaacgacc atgaacgaca agcgagacga ccagaacaac cccggcggca cggacggcac
     3121 gggcggccca ggcggtacgg gcggcacccg cggcccggac aacccggacg acccgacggc
     3181 gtacatgcac gaagtggagg agctggaacg cgagtccagc accgccgccc gcctcttcga
     3241 cgtgcgccgc atcatcggcg gcctcttcgt ggtctacggc gtgatcgtga ccatcgccgg
     3301 gatcttcgcc tcggaggagg acctgaagaa ggcccaggac atcaacatca acctgtggac
     3361 gggactcggg atgctcgcgc tcggcatctt ctttctggtc tggctgcggc tgagcccggc
     3421 cgtcccgccg ccgccaccgg aggaggcgga caccgcgggc ggtgacccgc tgctgaagta
     3481 gcgccgggca ggcggccgta cggaccgggg gtgtacggcg cgtacggcgt gtgcgcacgg
     3541 ggcgggtggc ggccgggccg cgtcactcgc cccgcgcgta cgggcccgtc gcccggtcca
     3601 gcaggcccgt acgggcggcc agcgccgccg cctccagccg cgagccgacg tccagcttca
     3661 tcagcacccg ctgcacgtgc gtacgggcgg tgctcggcgc gatccgcatg cccgccgcga
     3721 tcagccgggt gtcctcgccc tccgccaccc gtacgagcac ctcgacctcg cgcggcgtga
     3781 gcatctggag gaggcgctgg ccctcgtcgt caggctcggc ggccgggttc agcagttcgg
     3841 tgaaggcgtc gcggagcagc tgcggcccga cggccacctc accggcgcgt gccttcatca
     3901 tggcgcgctc gacgccctcg atgcgctcgt cgttccgtac gtagccggag gcgcccgcgg
     3961 cgaaggccgc ggcgatgccg cgcgggctcg gcaccgggcc cagcaccacg accgctatct
     4021 gcggcttctc ccgctttatc cgcagcaccg ggtcgaagat gcccggcgcc gcgggcgtcg
     4081 cggtgcccag caggcacacc tcgggcgcgc ggctgagcac cagttcggcg gccccggcgc
     4141 tcggcgcggc ggccgcgagc acgcggtgtc cgcgcagctt cagtgccgag gccagcgcct
     4201 cggcgagcag acggtggtcg tccaccacca tgagccgcac actcatagag ccccccaact
     4261 cccgctcccg ccgggccgcc ccgcggctgg agcccgcccg ggcacgggcg ctcgcccacg
     4321 gaagctacac gctcccccgc cgttctgcgc ccaaacgtcg ggaagccgcc cggaatacgg
     4381 cgatccccgc ctcgccaccg cggtgcggcg gcgaggcggg gacagcatgc ccgtacgcct
     4441 acggccgtgt ccgctagccg ccgaagccga cggccagcag ccgctccttg gtgaacgtgc
     4501 ccgcgcggtc cgtcacgtac ttctccggca gcagcagctt gccgttcccg tacacgacct
     4561 cggtgtcctg gccgtacgtg ttcgggccga gctcctgctc ctcgtccacc gagtcgttcg
     4621 gcagcttgag atacggcgtc tgcttgccgg ccttcggctc gatggcgacg atctcaccac
     4681 cggagtcgta cgtcggcagc ttgtacccga tcacgttctc gccctccatc tggatgggca
     4741 tgatcgtgcg cttggcgccc gcgtccgact tccacttggt cttgccggtg gtgaagtcga
     4801 aggccatgac ctcgttcgtc tgaccgtagt ccgacgagct gtcgtcgtgc tccttcgtcg
     4861 acaggtacac cgcgtccttg ccgaccgtca tgccgaagca ggactcgacg tccagcccgc
     4921 acgggttgtt gtagcggtcg ccgccgaggg agatcttcgc ggccagcttg ttgttggcga
     4981 cggtcatgat gtccgtcggc gtcgagtcgc ccgcgccgac caccaggacc agcggcgccg
     5041 tggacgggat ccgcacggtc tccgtgccct tcggcacctc gaactccgag acggacttgc
     5101 cggtcttcgg gtccagctcc tggatcgtga agtccggctt gtccaggtca ccgcacttga
     5161 cgacggccag cagcttcggg ccgcccgcgt acccctcgtc cttgcagtcg ccgctcggct
     5221 tggcctgcca gatcggcttg ccaccggtga tcttgaagcc gacggagccg ccgatccacg
     5281 ccgaggcgac cgtgccctgg ctgatcgtga cgttctcgac gctgatggtg tcggcgcccg
     5341 gcatcgtctc ctgccagacc ttcttgccgg tctccatgtc gatcacgacc atctggttgc
     5401 aatcggcctt gctggacttc gtctcctgcg tgacgatcgc cgtcttgttg tcctccgtct
     5461 ggtgcggcga ggcggcacag accgagccgg acagcgggat ctcccacgcc ttggcgccgg
     5521 acttgccgtc gtgcgcgacg acgctctcga ccgacgtctt cacgaagacc ttttcggtga
     5581 cccacgcgcc ggggacgctg acctggtcgt cgaccgcggg ggcctccatc ttggcgagca
     5641 gcttggcgtt gaggttcgtc ggcttcttgt cgccgccgcc tccgccgccg ccaccggtgg
     5701 cgccctcgga gctgcccttc ttgtcgccct tggactcgtc gtccttgccg ccgtcgtcgt
     5761 ccttcgtcag gaagaagacg gcgccgcccg cgatgagcac gacggccacg gccaccgcga
     5821 tgatcacggc gagcttggag ttgccaccgc cgggtccgcc ggggccaccc gggccgccgg
     5881 ggaatccggg gccgccgggc gtcgtcggat agccgcccgg gtcctgcccg tactgcggct
     5941 gtccgtaggg cggttggccc tgcggctgcc cgtaaccgcc ggggggcggc ggggtcggcg
     6001 cgccgaagcc gccgccgggc ggcgggccgg gtggctgctg cgggtagccg taaccgggcg
     6061 tctgaccggg gtcctgcggg tatccgtacc cgccgttctg cccgccctgg ggaccggggg
     6121 gcgggtcctg cggcgcgccg aagccgcccg acggcggctg actgggcggc ggaggcggct
     6181 gcgacatgac attccctcgt tcatgaggca gaccggacgc ccggcgcctc aaacccccgt
     6241 agggccgagc gaatcggaca tttggcccgc cattgctgac tggtgagcgg aagttctttg
     6301 tatcaccgga caccgacaga ccggacttcg gttcccggag gggagccgac gtcgttacca
     6361 gaatgcagcc cgcgacgtga accctccgcg ccgcggagcg ggaaacgggg cggaacggcg
     6421 cctgtgttcc gcctgtgccc cacccccagc cctcgcctcg cctgcgccct cgcccgagtc
     6481 ctcgccggcg ccccgccgga acgctcagcc gtcctcggcc agttccagcc agcgcgtctc
     6541 gaggttgtcg cgctccgtgg tcagctcccg caggcgcgcg tccagttcgg cgacgcgggc
     6601 gaagtccgtc gcgttgtccg cgatgtccgc gtgcagctgc ttctccttgt cgccgatgcg
     6661 gtccagctgc cgctcgatgc gctggagttc cttctgcgcc gcacgggaca ggcccgcgcc
     6721 cttgggccgc tcgccgccac ccgccgtacc ggacgtcccg gacgtgcccg tggcgccgcc
     6781 cgacccgccc gcctgcggcg ccgccgccgc gggtgccgcc acgggcgcgg caggctggtc
     6841 ggcggcgcgc atcctggccc gccgctccag gtactcctcc acgccccgcg gcagcatccg
     6901 cagcgtgccg tcgcccatca gcgcgtgcac gcggtccgtg gtccgctcca ggaagaaccg
     6961 gtcgtgggag atcaccacca gcgaacccgg ccagccgtcc agcacgtcct cgagctgcgt
     7021 cagcgtctcg atgtccaggt cgttcgtcgg ctcgtccagg aacagcacgt tcggctcgtc
     7081 catcagcagc cgcaggatct gcagccgccg ccgctcaccg ccggacaggt cccccacggg
     7141 cgtccactgc cgctgcttgc cgaaaccgaa gcgctcgcac agctgcgagg cggtcatctc
     7201 gcggcccttg cccaggtcga cccgggaacg tacctgctcg acggcctcca gcacccgcca
     7261 ggacgggtcg agttcggcga cctcctgcga gaggtacgcc agccgcaccg tgcgcccgac
     7321 cttgatacgg ccgcccgccg gctgccgttc gccctcgctg cgcgccgcct cctccagcgc
     7381 ccgcagcagc gacgtcttgc ccgcgccgtt cacgccgacc aggccgatcc ggtcgccggg
     7441 cccgagctgc cacgtcagct gccgcagcag caccttgcgg cccgcctgga ccgtcacgtc
     7501 ctccaggtcg aacacggtct tgccgagccg tgagcccgcg aagcgcatca gctccgcgct
     7561 gtcacggggc ggcggcacgt ccgcgatcag ctcgttcgcc gcctcgatac ggaaccgggg
     7621 cttgctcgta cgggccgggg cgcccctgcg cagccacgcg agctccttgc gcatcaggtt
     7681 ctgccgcctg gcctcctcgg tcgccgcgat ccgctcgcgc tcggcccgcg cgaagacgta
     7741 gtcgctgtac ccgccgtcgt actcgtgcac cgtgccgccc tgcacgtccc acatccgggt
     7801 gcacacctgg tccaggaacc agcggtcgtg ggtcacgcag accagcgccg aacgccgcgc
     7861 ccgcagatgc cccgccagcc aggcgatgcc ctccacgtcg aggtggttcg tcggctcgtc
     7921 caggacgatc aggtcctgct cggcgatcag cagcttcgca agcgcgatac ggcgccgctc
     7981 gccgccggac agcggcccga tcaccgtgtc catgccctcc gggaaaccgg gcaggtccag
     8041 cccgccgaac agccccgtca gcacgtcccg caccttggcg ctgcctgccc actcgtggtc
     8101 cgccatgtcg ccgacgacct cgtgccgtac ggtcgcctcc gggtcgagcg agtcgtgctg
     8161 cgtcagcacc ccgagccgca gcccgcccgc gtgggtgacg cggccctcgt cggcggtctc
     8221 ccgcttggcg aggatgcgga tcagggtggt cttcccgtca ccgttccgcc cgacgacacc
     8281 gatccggtcg ccctcgctga cgccgaggga gagaccgtcg agcagcgcac gggttccgta
     8341 caccttgccg acggcttcca gattgacgag attgacagcc atctcactcc tgtatcgcgg
     8401 gatcagcctt tcagggtacc ggccgcgggg tctccggccg cgcggccgct ggcgggcccg
     8461 cggcggggcc ctcgcggcgg cggttcacgg gccgccgcgg gccgcccgtc gcacgccggg
     8521 ccgacgggcg ggatcggcac cgtgccgtgc cgggtgccgc cacggcgtgg ccgagggcgg
     8581 tcctcagacg ccggacgggc tgggggctgt ctcttatccc catctgatgc ttccgacgaa
     8641 ggcgtaggag tagatctcgt cggtgtccgt gcaatctaca aaaacaaccg tagtgcgccg
     8701 cccgttcccg cagggggact tcggacgggt cgaccgcgag tcgcagggtc gggacgcggt
     8761 cgaagagctt cgacaggccg atgcggaggg tggcgcgcgc gaggtgctgg ccgaggcact
     8821 ggcggatgcc gaagccgaac cccacgtgct ggcgcgcgga gcgtgtgacg tcgagttcct
     8881 cggcgtcgct gaaggagtcg gggccgcggt tggcggcagg ccgcgttcac gtagagtcgc
     8941 cgcgtgacga caggagcggg tccggccggc cggggggttc ggcagggccc gctttctcgt
     9001 gcgcgcgcac gttccgtacg gcggccggaa ccgtcccgta cgtcgacctg tccgtaaggc
     9061 agcgcccgtc ccgtacggcg ctgtccgccg cgtgcggcag cctcccgtac gtcagtggcc
     9121 gccgcgtacg ccggcctccg cgcgctcccg ttcgtgcagg cccgcgatcc gccccaacgc
     9181 ctcgtcccgc gcgcacggat acgcgcccag cgtcgtgtgc cgcgccacga tcgcgccctc
     9241 cgaccgcatc agcccccagc cgcggcgtac gaggaacggc acggacttgc gcccctcgcg
     9301 cacgtcacgc agcagccgcc ggcggaacgt ggtgagcggc cgcccgcgca ggcatatcgc
     9361 gtcggccagc aggctcagtt cggcgcagcg cgcggcgatg tccgcggcga agatcccctc
     9421 cgcgacgaac aggggcgcgc cgcccagggt gagcgcctcc tcgcccgtac gcgcgctggc
     9481 cgcgatgtcg tagagcggga ccgttgtccg cccgtgctcg cacagctccc gaacggccgc
     9541 caccgccgcg tccgcgtccc acgagcccgg cgcgtcccag tcggtggcgc cgcccgggag
     9601 ctgcgggagg gtcgggtcgc caccctcctt gtagaagtcg tcgagccgca gcaccggcag
     9661 cccggcacgg gcggcgagcc gcgtcttgcc ggagccggac ggcccggtga gcagaacgac
     9721 gcgggcgcgg gcgcgtacgc gagcgcgctc ggcggcgggc gcgggcgcgg gtccgggcgc
     9781 ggggctgggt gcgggggccg tacggtcggc cggggtgcgg tcgcagtcag ggcgggcggc
     9841 gctggaggtc acgagagacc attgtcgggc atacgtacgg cctctggcac gggcccgtac
     9901 ccggaccatc cggtcggcga acgcggcgcg cccgatgcgc cggcgaactc cttccgtgca
     9961 cggcgggccc gaccgggacg aggggcggac cgccgcgctc tcagctgccg gccgggcgct
    10021 ccccggccgc gcccaggacg atggagtgca cgacgctctc cacccgttcg tcgagccgca
    10081 gcagcccgtc cagttcgtgg tcgtagaagc ccgacaggca cagggacccc gccgacacgc
    10141 cctcggcgga caggcagatc ccctgcccga tgtggcctgc ttccaggagc gtgaagcggt
    10201 agccgcgttc ggcgtacttc gacgtggagc gggagaagac gccggtgagg acgaccaccg
    10261 cgccggcgcc ctcgaggtcc tcgggctgca tgcacgactt ccgcagcgcc gccgccgggt
    10321 cgtcggggtc gatgcggcgg agttcaaggg cgtgcggcgc gtagtagtag atgccggggt
    10381 cgaggccgtc gacgtccgtc acggcgacga agcactcgac ggggtaccgg ccgccggccg
    10441 agggggcggg ccggtgcatc ccggtcgtac cgacgcccac acgcaggatc gtcgccaacg
    10501 accgccgcgt cagcggtgtg tcgccccacg taccgtggtg gctgcggcgc cgtgcggcca
    10561 gttcgccgag cggggcgagg gggagcggtt cgtcgtcgag tacgacggcg gacgccttcc
    10621 cgaagcggtc accgcctccc cgcagccggt ccagatcggt ttcgaagcgc tgtacgggct
    10681 cggcgaagtt ggcctgccgg tcgcggctga acttcgagtt ctcgtgcagc tccgccgcca
    10741 gcggcgcgta cgcgcgaggg tcggagaccg gcgagccgtc cggttgtgcc agcatcgttt
    10801 ccgtgatcct tccagtccgg gccgggattg gcgccggcgg tgggggctcc ggcgcttccc
    10861 cgcctacgcg aagaagtgcg gcgcggggtt gagttcgtcc tcgcgggccg gctcccgccg
    10921 gtacccgagt tcgaccggga ggtcgtagag gcgccgtccc gtgcgggact gcaacgctcc
    10981 gaagtccagt ggctgcgcgc cggggaccag caccttgcag acgtgccagc cgagtccacg
    11041 caggtccggc ggagtgaggt cgacggtgat gacccgcatc ccccggcggg cgaccgcgtc
    11101 cacggccgcg tcgagcgtcg tgcatccggc cgacgtgtcc gacgtatccg atgtattcga
    11161 tgtgtccggc gggttccagt cggcgtggtc gtcgagcagc cagtccagcg tgtcccggta
    11221 gccgggcagg cagctcatcc ggatgtgctc ctcgggctcc gccaggtcct ccatcggccc
    11281 cggctccgcc ctgtccgggt atccgcggcg gctcatcacc gcggatatct ggaatgcctc
    11341 gagtacggct ttccgcagcg ccgacgggta gtccccccgg cacgccgccc cgaagcagaa
    11401 cggcggcacc cggtcgctcc gcgtcagcac cccggccagc accaccggtt gcccgagatc
    11461 cagtgtgaga tcccacgccc gtacggtcat cgcgtgccag cgcggcgcgg aagccacgaa
    11521 gccgtcgacg tcgtcgcaga tccccgcgaa cgggatctcc ggcggggtcc agcggttcag
    11581 gtgcctgatg gtgaacgcgt cccgctcctc gatctcccgg agcccggcca ggacggccgc
    11641 tgacggatcc gtgtgcgcgg cgaggccgtt ggtcgtccag ggcgcgagtt cctccccttc
    11701 gaagcgcgac ttgtaggacg gcagcgccag ctgggccggc accagcaccc gccggtcctc
    11761 cgtcaggtcg tggcccacca cccagccgcg cggcgccttc tcgtcgaagg cggtccagga
    11821 ggactccttc gggtgtggca gcacgaacga ctcgccgtgc acagcgtcgc cctcgaactc
    11881 gtcgaacgtg ccccactcca cccgcgcgtg cgcggctccg accagggagc cgtagcgttc
    11941 gaccgtctcg ccgacggcgg cggaccgcgc ctcggccagc gaggtgccga tcccgaagcc
    12001 ggtgaccccg tagtccttcg gtacgccggg cagcacctcg gggcgtgcgg ccggggcgag
    12061 ccgggccacc gtcgtacggg gcagcagctc cgagacgaag ggcacgagct gccggatgat
    12121 cccggttcgt ggcgatacga cggccgccgt gtcgaccccg gcacgcgcac gggggacggg
    12181 cggggccgcc gtcacgtcac tgcgcatgac cacagctttc gcacatgggc acccgcagga
    12241 ccgggtgccg ggtgagtttc agggtcgtga agctgagctg gagaagtacg ggggcgggcg
    12301 cctcgttggc gtgcccggcg aagacgttga ccgcccgcag ggacgccagg ctggtcagca
    12361 gcccgtcgcc ggcggccagt ctccccgccg gagcgaatgc cagcggcggg cccccggcgg
    12421 acgcttccgt gcccccggac tcaccgggcc cgggggccgc ggcgcgctcc cgtacgcaca
    12481 ggcagtcgta gcacgcggtg cgccggggga cgacgacgtg cgtgagaacg accgtgacgc
    12541 cttcgaacca cccggccagg tacgggactc cggcgcggcg cgaccagcgg tcgaggcgcc
    12601 tgaggtgctc ctcgtcccgg tcccgcgcca gcgagacgac gaacgacggc gcctccccgc
    12661 tcagcgcggg cgcgtccgct tcgtcgagga ccgggcgccg cgacagccgt acgccgaggc
    12721 tggcgctcgt caactccgcg aaccgcgcgc cgagttcctc gtcgccgagg cacacgatct
    12781 cggcccgcgc gccgtcggcg gtgacggcgt cggacagtcc ttcgtcggcg aagaggcgca
    12841 gcgccgcgtt cgcctcgcgg tcggctccgg gccccttgtc gagctcggcg agggtcgtga
    12901 ccagcccctg ggactccagc cgcgccagga gccgggcgac cttctcggca ggcgcgtcga
    12961 cctcccgcgc gaccgcgccg acggagcttg gccgctcgac ggcgcagagg acccggcggg
    13021 ccaggcccgc ggtccttccg cgcagggcga cgtctccggt cacgagccgg acggtgatgg
    13081 ttgaatcgat ttcttcgacg gaggccccgg ggctcaggag gtaggtcaca tccacggtgg
    13141 ctgccacgtc acgggctcgg tctccatgta cgacatggcg atgattcgta catggttggc
    13201 gggaacgccg tcaatccttt acgggctggt gggaggggat tcccagaccg gtcaggctgc
    13261 tgcgtcggca ccggggccag cccttgaccg gctttcgggg tgaacgttag cgtcccgtga
    13321 atcgatttgt gaaatcgatt tctcaaacta ctcaggaggc aagacatgac accggagcag
    13381 cagacccccg gcatcgcacc cgacagcagc gtcgacacgg accccatgga caccatcgac
    13441 ctgacgatcg agaagctcgg cccccgcctc gccctcgaca acaccgaggg cggcagcagc
    13501 gccaccaccg gcagctgcac cctcagcggc accatgtgcg gcggccgtgg ctgagagcgc
    13561 ggcgcggctc ggcccctcgc tcgtgagtgc gtgagtgcgt gagtcacatg ccccaagcca
    13621 ccccggacgc agtcgagtcg gctgagggaa cgcagctgct cccacgctcg gacaaccgca
    13681 tccttgtccg cgggtggaac cacggggccg agctggccgg cgggcacgct tcgctcgccg
    13741 gccggctcct cgccgctgcc cgcggcggct gtaccccggg ggagctggcg gcgttgacgg
    13801 gcgtgccctt cgtacgcgtc caggctctgg tcgaacggct cttggagcag gggctgctgg
    13861 aaccgagccc cctgcggcgc gggcccgccg ccccgctccc cgccgcgcgg gcactcggtg
    13921 cggccaccga gcccggatcc gtcctggacg ccgtcgtcac cgacgacccg gccctcgccg
    13981 aacacctcac ggccgaactc cggcaccgcc cgggtacccc ggacttcgtg gtcaccggga
    14041 acgcggccga gctcgcgcgg cgcgcggacg gccgcgccgt caacgccgtt ctgcccagac
    14101 acctcgtcga gcgcgacgac gaccccgcgg tccgcggcgt actgaccacc gggggccgct
    14161 gggcctgcta ctggcgcgag cacgggcgta ccgtcgtcac ctcggacctc tcctgttccg
    14221 ggcccggcta cggcctgtgc ctcgcatgcc tccggctgcg cgaacgcgcg ggcgcgcggt
    14281 caccccggcg cgggggcgac gacggccacc gcaccgtgta cgcgcctggc aacgtgtacg
    14341 cgcctcccac cgcggcgctc ctggcgcacg tcctcgcggg cctgcgcgcc ggtccccccg
    14401 ccgccgcggg cggggccgtg ctgtacgagc tccaccacga ccgcgtgcgg ctctcccgcg
    14461 tccgcggcct gcccgtgtgc ccggcctgca caccactcgc cgggggcccg tacggcgacc
    14521 tcctgctgac gtctccaccg cggtccctct ctccgccgga aacgcccgcg gtccacgccg
    14581 cccggccgga cggcgcggtc cggccaccgg ccgcggcacc ggaggacgca ctctccctcg
    14641 agcagatcac cgaccggtgc cggcgctcgt cggacctgcc cgcgccggaa ctggccgcac
    14701 tgctccggga cctcggtgag ctgtacggcc gccggggaac ggtgctgcgt gccatacggc
    14761 ccgaagtccc cgccgtcgcc gcggactgct tccacgccgt cgcggcggac ctggcggacc
    14821 tccggcggat cagtgcgtcg aacgggcagc cgcaggcgta cgacgcgttc ggcggcgcgt
    14881 ggacggcggc cggcgcggtg caacgctgcc tcggggaggc cgtcgaacgg tactgcgctc
    14941 tggtccacgg tgccgcgcgc cgggtcgtgt ggggagccgc ggacgaactc cccgacgccg
    15001 tcccggtcga acggttcgcc acgctctccc cggcggaact gcgcgactcc ggacgggacc
    15061 tccgccccgc ctcgtcccgc tcccgcctcg gctgggtgga aggccacagc ctcacccgcg
    15121 cgcgtccggt gctcgtcccc gcccagctga gctttctcgc gtacacggcg gcggcgtccg
    15181 aggacgcggt gcagcccggc tcgaacaagg gcctcgccgc gggccgcagc gccgaccggt
    15241 gcgtggtcca cgggctctgc gaactcgtcg aggccgacgc gctgctcatc cacttcctca
    15301 accggagccc cgtgcccgag atcggcctcg gcgacaccgg catcccgcgg gtcgaccgtg
    15361 ttcaccgggc cgtccgcgcc gcgggcggac ggctgcgcgc ctgggacttc gccaccgacc
    15421 tcgccgtgcc gacggtgctc gtgatgctcg aacggcacga cgggacgggc ccggtggcga
    15481 cgttcggcat ggcgacccgg ccggacccgg ccaacgcact ggagaaggcg gtactcgagg
    15541 cgctgcacgc cacatgctgg ctgaccggcg agatggccga ggcggcccgc gcgttccccg
    15601 gtgtccccac gccggagtgg gtgaccgcgc gggagcaggc caagagcctc ggagcgtcga
    15661 gcgcgtatct cgcctctctc ggctggctgc tggacaggga ggtccgccgg ccgttccggg
    15721 agtacgccgc cggatacccg gaggtcgcgc atgatccggc ggcgcagcgc cacgggctgg
    15781 tgggcgccct ggcggcggcc ggtctcgaac ccgttgccgt cgacctcagc acacccgacg
    15841 tacgcgacgc cacgggactc gaggtgtggc gctcgatcgt gcccggcctc cagcccttct
    15901 cgatcgggac gctccaggcg cgggccggcg accggctgtt ctccgtcccc gtacgcatgg
    15961 ggtaccggtc cgcgcccgcc gcggagtccg acctcaaccc gttgccgcac ccgtgtccgt
    16021 gaaggacgcc gccgcccacg tcccacccgt ccacccgtcc cgacgtcccc cgtcccccgg
    16081 ccctcgtacg gagagccccg actgagagag agccccggtg ctgagccgcg aattcgcccc
    16141 cgagcgcccg aaactggccg agcccgtcga ggcgacggtc gacggcgacc aggcgtacgt
    16201 acgcatcggc acgcccccgt cgtacatccg gctcggtgcc ccggcctggt ccatcacccg
    16261 cctcctcgac ggctcacgct cggtgcgcga ggtcgcgcac gaggccggct gtacggagga
    16321 acaggtgcgg cggctggccg accagctcgg cggcggcggg ctgctcgagg gctcggaggc
    16381 acagcaggag cggcacgaca gcgacgtgca ccgccagtcc gtgttcttcc tcaagttcac
    16441 ctggcacgac ccgcgcgccc tcggcacggt gtacgacgtc gtgcgtcgct ggattccgcc
    16501 ccggtggttc gccgcactgg cggcgacgct gtgcgtggcc ggcgccgccg cctgcctcct
    16561 gtcgtggacc agcatgatct cgcaggccca ggaagccgtc agctggtcgc aggtgtggca
    16621 ggtctggccc gccatcctgc tccgcgccgt cgtccacgaa ctcgggcacg ccttcttctg
    16681 cctgtccttc gggcggagcg tcgccgcact cggcttcggc ctgtactact tccagccggt
    16741 cgccttcacc gacgtgagcg acatctggct gctgcgcaga cgatggcagc gcgtgctcgt
    16801 gcatctcggc ggcccgatcg tcgacgtcgc cctgctggtc gcctcgggcg tcaccgtcct
    16861 cgccgcgtcc gacggcctgg tggagacgtt cgccgcgtat ctgctcctct cgactctcgt
    16921 gggcgccgcg gcgggcttca accccctgct ccgcagcgac ggttacttcg tgctgacgga
    16981 actcctgcgt gaggacgacc tccgtgatcg cgccctggtc ctgatggcca ccaccgcccc
    17041 gtggcgcctc tcggtacgtg accggaccag cgccgtgctc gtgacgtacg gcgcggtgtc
    17101 gttcgtctac acgctcgtca tcgtcggcat cggcgcgaac gtggcctcac gtttcgtgct
    17161 ccacaccgtc ctcggcttcg acgcgttgcc gcaggcggtc atgtggagcc tcggcgcggg
    17221 gatcgccctc gtgctgtgga ccgtcatgct ccggcgcgcc cgtaacgcca ctctggcctg
    17281 agcccggggg acgctactcc tgctcggcca ccgtcttgcc gccttccagc atcgtcttca
    17341 gtgccgaaag gatcatgacc cagccgccgc tgacgctggc cagcatcttg ctgtcggcgc
    17401 tgtcgaagcc gtcgtggatg atcgtcagtt tgacgccgag cgacgcctcc tcggccggct
    17461 cgatctcgaa cgtcacctgc gaacgctcct tgcgggcctc ctcgaactcc tcgtcggaca
    17521 tgcccagcat ctcctggtgc atgggctgga gcgtgtgcca ggtgtacgac agccgcttgc
    17581 cgggctcggc cgccagcacc cgctgcccca actcctcgaa ctccccggcc ggatcggact
    17641 tccaccgcac cggcgacccg acctcccagg tggactgcgg gccggtgtca ctgaagtaga
    17701 ccttcgtgaa ctccggcttg gtcagcgcct cgtacagctt ctccggcgtg gtctggatgt
    17761 aggtgacgta gacgaacttc gcactgctca tgggggtgct tccttccagg gatcgcttca
    17821 gggcggagag cgcgtcgagc cgcccgcgct cgtactggcc gatccagcgg tcggccagct
    17881 cgtggatggg cacggggttg aggtagtgca gcttctcccg gccctgccgt acgacgacga
    17941 ccagccgcgc cgcctccagc accgccaggt gcttgctgac ggcctgccgg gtcatgtcca
    18001 gcccctcgca cagctcgcgc aggctctgcc cgttccgcac gttgagccgg tcgagcagcc
    18061 gccgccggct ggcatcaccg agcgccttga atacggcgtc catgcctcac ctctgcctct
    18121 gcctttcgcc tccagattgg caaccaaatg gttgcctgtc aatccgggag ggtggccaag
    18181 gcggtcacgg ggcgggcagc ggctatcggc cagggagccg tcggccgggt ggggcggctc
    18241 cgtgcggcgc cgggcactcg atgcactacg ctgtgtgtct gatccgtcac ccataggtta
    18301 ggcaggtgga acgatgagct cccgtccgcg tcacgcgagg acgaaacagc cccgccgctc
    18361 gcgtgcgttg ctgcgcgccg ggctgaccgt tacggcggcg ggggcggcgg tgatggccgg
    18421 gagcgggatg gcctccgccg acacgaggat caccggggag gagacggggc tgccgatcgg
    18481 ttcgatcgag acggacgccc tggaggatcc ctcgggtgtc ttgaagcggc agctggaggg
    18541 gggcctttcg gggtcgctcg ggcccgcgaa ggaccttccg ctctaccccc tcgccggcac
    18601 cgccgtcgac ccgctcgcga actccgtcgg cgcccaggtc gccgacttcc agacggtcag
    18661 caccgaggcc gtcaccggcc ccctggcctc cggctccacg ctgcgggagc tgcccgtgct
    18721 ggggcaggtg gccaccgcgc tgccgggctg aacggcctga acggcctgaa cggtccgaaa
    18781 cgggcctcgg tcgtacgggt tcagtccgcg gccggggcgt tgggcacgta gcccaggtcc
    18841 accgggaccg gcggcgcccc ggcccgcccc tcgcgcaacg gcgtcagcag tgcgggcagt
    18901 tgcggcggcc acagcggctc cggacaccgc gccagctccg gcggcgtcca ccagcgccag
    18961 cgcagaatgc cgtcctccgc gtgcgcggcc cgcaggtctc ccacgggttc cggccggggt
    19021 cccggcggca ggtgggagag atagatgtgc tcccactgcc gtacgggcac gccctcccgc
    19081 gtgtagtcgt gctcccaggt gcacagcagg gggcccggct cgacgtccgt ccaacccgtc
    19141 tcctcgcgca gctcccgccg cgcgccctcc tagggtgtct cgcccggctc caggccgccg
    19201 cccggcatgg cccagtggac gccgacctct tcgttgtcgt agcggaacag gaagatcgcg
    19261 ccctgggggt cgaggacggc aatccgggcc gcccgcctgg gagttcgcat gcggccagcc
    19321 tagtcttctg agtcgggaat tctgttcaga tgtgtagggt tgcctggtgg cgcgtattgg
    19381 gcggccgaag gccgagttga ttctgtcgga ggaggagcgg gcggcactgg aggggtgggt
    19441 gcggcgccgt tccacgccgc aggcatgggn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    19501 nnnnnnnnnn nnnnnnagat gtgtataaag ggcagccgtt acggccgcgc ccgcccgcgc
    19561 ccgtaggacc gcacacacgc gccgcccgta cgaccgcgcc cgcacgcgcc gcgcccgtac
    19621 ggacccccgg tcagtccgtc gactcgtacg gctcgggcct gtccgggtgc tcgtactccg
    19681 tctgcggggt gccgcgcggg cccgaccccg tctcgtcggt gtccggcagc tccgcgtcct
    19741 cctcctcgcc gcccgggacg agttcctcgt ccggcgtctc gccggcggct cccgcctgct
    19801 ggtccggcgg gtcacgcggg attcgggccc cgcggccgtc cggttcctcc gctggttcag
    19861 tgctcatccc tccatcctgg cccctgcggc ccgcccgtgc cgtgtcggtc ccggtcccga
    19921 ccgcgtcact gggaaattgt cctgttgtca ggtaccagat cttgtcgcgt acatggctcg
    19981 gctgctttcc ttgccgggct tgacgcggac ggaggaccag ccgccggccc ccaccgaagg
    20041 agtacggatg tcccgcaccc cggccggccc cccgtatccg ccgccgcgct gaaccacccc
    20101 tggcggcagg cccgttccgg cgcaccggcc gacgccaggg gtggagcggc ggcccgcacg
    20161 actcccccca cacgcgccgg acaccagaag ggaaagcgat gaagtcagga gccaggaagc
    20221 gcacatggcg acgcggcatg gcggtgctct gcggcaccgc ggccgccgca gcgatcaccc
    20281 tcaccgtcca gcccgcgacc gccacgaacg cccccgaagg ggactcgatg gccgacgcgt
    20341 tcacggacgc cgccgaggag tacgacgtcc cgcgcgatct cctcgtcgcc gtcggatacg
    20401 gcgagaccca cctcgacggc cacaacggcg agccgagcca ggacaacggc ttcggcgtca
    20461 tgcacctggt gagcaacccc gaccgggact ccctcggacg cgcctcgaag atcaccggtg
    20521 agtcggagac cgacctgaag cgcgagacac gcgcgaacat cctcggcggc gccgccgtcc
    20581 tccgcgcaca cgccgacgcc ctgggcctcg acgccgccga acgggacgaa ctcggcaagt
    20641 ggtacccggc cgtggcccgc tacggcggcg ccgagaacaa gcagctcgcc aagttctacg
    20701 cggatagcgc gtacgagatc ctcgccgacg gcgtacgcgg tggcacggac ggcggcgacc
    20761 gcgtacgcac ccgggcccgc gacgtcgcac cggaccgcgg cggctacgcc gacgtgcccg
    20821 acctcggcac gcggagcccc gactacccgc ccgcgctgtg ggtgcccgcc cacgaggcca
    20881 actacgcggc gggccgctcc gccgccatca gccaggtcgt cgtccacgtc acacaggggt
    20941 cgtacgccgg cagcatcagc tggttccaga accccgaggc cgaggtcagc gcccactacg
    21001 tgatccgttc cgccgacggc gagatcaccc agatggtccg cgacggcgac accgcctggc
    21061 acgcgcggga cgcgaactcc tccgcgctgg gcatcgagca cgagggcttc atcgacgacc
    21121 cgtcgtggtt cacggacgcc atgtaccgct cgtccgcggc cctgaccaag cacctgtgcg
    21181 acacccacgg catccccaag gaccgcgagc acatcgtcgg ccacagcgag gtgcccggaa
    21241 acgaccacac cgaccccggc ccgaactgga actgggacac gtacatgggc tacgtcaacg
    21301 gctgaggcac acccccgagg caccgccccg ggcccagcgg ccgccgccgg aggaaccgtc
    21361 cggcggcggc cgccacccct ccccgtaccg tggagtggtg aactgcacct tctgcgccat
    21421 cgtggccggt gagacgccca gccaccgcgt gtacgaggac gagcgggccg tcgccttcct
    21481 cgacacccgg ccgctgttcc ccggccacgt gctcgtggtc ccgcggcggc acgccgagac
    21541 cctcaccgac ctgcccgaca gcgacgtggg ccccttcttc gggcgcgtcc agcggatcac
    21601 gggcgccgtg gagcgggcca tggaggcggc gggctcgttc gtggcggcca acaaccgggt
    21661 cagccagtcc gtgccgcact tccacgtgca cgtcgtcccg cgcaaccgca aggacggcct
    21721 ccgcggcttc ttctggcccc gcggccgcta caccgacgac gcccacgccg aggacgtcgc
    21781 agcccgcctg cgcgccgccc tcgaggactg accacggcag gccggacagc gcccggcgca
    21841 ctaaaatggg cagcgtggcc cggcccaacg aggacgtgcg ggcgctcctc caggagtacg
    21901 ccgagctcct cctcatcacc ggcaaggacg cgtacaaggc ccgcgcatac gaaaaggccg
    21961 cacgcgccat cggcggctgc cacgccgacg tctccaccct cgacgccaag ggcctgcgcg
    22021 agatccccgg cgtcgggaag tccatcgccg acaaggtcgt cgagtacctg cgcaccggca
    22081 gcatgcccgc cgtcgaggag gagcgcgccc gcatcccggc cggcgtacgc cgcctcatgg
    22141 agatccccgc cctcggcccc aagaaggccc tcaccctcta cgaggagctc ggcgtctcct
    22201 ccgtcggcga actccgcgaa gccgtcgaac aggagcggct ccgcgacctc aagggcttcg
    22261 ggccgcgcag cgaggagaac atcctccacg gcatcggact cctcgaagcc tccggcgaac
    22321 gcatccccgt acacgccgcg acggagctgg ccgaggagat cgtggcggcg ctctcggccg
    22381 tccccggctg cgtggactgc gcctgggccg gctcgctgcg gcgcatgcgg gagaccgtcg
    22441 gggacgtcga cgtactggtg gcggcgcgcc gttccgaacc cttcatggag gcgttcacgg
    22501 cgctgccgtt cgtcgccgag gtgatcgcgc ggggcgagaa gaagacctcc gtacgcaccg
    22561 ccaagggaac gcaggtcgac ctgcgggtcg tgccgcccga ctcgtggggc gccgccctgc
    22621 tgtacttcac cggctcgaag gcgcacaaca tccggatccg cgagatggcc gtacgcggca
    22681 aactgaagct gtccgagtac ggcctcttcc acaccgagag cggccgcaag atcgtctccc
    22741 gcaccgagga gaaggtgtac tcccggctcg gcctgccctg gatcccgccg ccgctgcgcg
    22801 aggaccgcgg cgagatcgcc gccggcctgc gcgacgaact gccgcagctg atcaccgagc
    22861 gcgacatccg cggcgacctg cacacccaca ccgacctcac cgacgggctg gcacccctgg
    22921 aggacatggt cgcggccgcc gccgaacgcg gcctgcgcta ctacgcggtc accgaccacg
    22981 ccccggatct gcacatgcag cgcatgacgc gggacaagat gctcgcgcag cgcgaacgcg
    23041 tgcgggcgct cgaccgcacc caccgcgggc tgcgactgct gcacggcacg gaactgaaca
    23101 tcggccccga cggcgaggtg gactggccgc cggagttcct cgcggacttc gacgtctgcg
    23161 tcgcctcggt ccactcacac ttcgggctgg accgggacgc gcagacgcgg cggctgctcg
    23221 ctgcctgcga gcacccgtac gtccacgtca tcggccaccc caccacccgt atcctcggca
    23281 aacggcagag catggacgcg gactgggacg ccgtgttcgc cgcgtgcgcc cgtacgggca
    23341 ccgccctgga ggtgaacgcc cacccgaacc ggctcgacct caccgacgaa ctcgtcctgc
    23401 gcgcccggga ccatggagtg aagttcgcgg tcgacacgga cgcccactcg gtgcccgacc
    23461 tcggatacct gcgctacggc gtgggcgtcg cgcagcgcgg ctggctgacc ccggaggacg
    23521 tcatcaccac ctggccgctg acgcggctgc ggcacttcct gcggaagagg gcggggacga
    23581 gggcccgtta ggcgtcaccc gcgcgggtga cgcgccggcg cgcggctccc accgccgcgc
    23641 cggccgtacg tcccgtaccg gcgtccccgc gcggggaccc cgacggctca gcgcttgcgg
    23701 agcttgccga ggagcttccg cgcctgggcc tgcttcttgg ggtcgcgggc tgcctgccgt
    23761 gccgagttga tcgccttctg cccctgcggg ctgcgggtga actccttgat ccgtgcgatc
    23821 agtccgggca tgtcttctcc ttcggggacc tgcggtgcct cgggacgcct cgttccggcg
    23881 tcggccgtgc tgccatcgtg acacgcccac cgccccaggc gcccgcggct gcggccgccg
    23941 ggggcaccgc cgcgcgccgg gtcacgcggt cagtccggcc ggggcgagtc cgtgccgggg
    24001 cgcggggtgc gccagtggcc gcgggtgaag tcggggaagt cctgcggggc accgtgggcc
    24061 cggatcgacg cgtggctcag cgggaccggc gcggtccacg tggcggcgtc gtacacgtcg
    24121 aagtcggggg tgagaccgag acgcatgcac tgcacgagcc ggtagagcat gaggtagtcc
    24181 atgccgtcgt ggccgcccgg cgggtcgggg tgctccttcc acagccagtg gtcccaggac
    24241 gcgtagtcct cgaagtcgcc ccactcgtgg tcgtcccggt ccggctcgag gtagatgcgc
    24301 gggggatagt cctcgaacac cccgcgcgtg ccgcccagcg tgttgatccg gctgtacggg
    24361 cgcgggttgg acacgtcgtg ttccaggcgt atgacgcggc ccttcgcggt ctggacgaga
    24421 ctgacggaca ggtccgccga gacgtagctc tccttccagc tctcgtctcc cggcggcatg
    24481 tgctccttcc ggtacgccgc cagcccgagc gcgggtgaac cgacgctgct gatgcgtacg
    24541 gcacggtcgc cccggttgag gtccatgtag ttcgccaccg gtccgaaacc gtggttcggg
    24601 tacaggtccc ccttcagccg ggtgtgccac ttccgccgcc aggggccctc gtagtactcg
    24661 gggtcgaaca tcagctcccg gagatcgtgc agatacgccc cggcgccatg caggagatca
    24721 ccgaacaggc ccgcgtgggc catgcgcagg acgcgcatct cgttccgccc gtaggcgcag
    24781 ttctccagct gcatgcagtg ccgccggctg cgctcgctca gatcgaccag ctcccacagc
    24841 tgctccagcg tcatcgccag agggcactcc acccccgtgt gcttgccgtt ggagagcgcg
    24901 gacttggcca tgggatggtg ccactcccag ggggtggcga tgtagacgag gtcgatgtcg
    24961 ccgcggcggc agaggttctc gtaatcgcgt tcgcccttgg tgtacagggc gggagcgggc
    25021 tgccccgcct tcgtgacctt ctccgccgcg gcggcggcct tgtcccgtac ggaatcgcac
    25081 agggcgacca cccgtacgcc cttcagcgtg aggaacagct ccagcatgcc ggcgccgcgg
    25141 ttgcccagcc cgaccagtgc gacgcgtacg gccgagcgcg gctcgaaggg cacgccgacc
    25201 atggtgggcg cgctgcgcgg gggcgcgtcc gtgccggtcg cggcggcggc ctcggcggac
    25261 gtggtgccca gtgcgccgat gccgagcgcg gcgcctgcgg cgccggtggt gtgcaggacg
    25321 gaacggcggc tgattccctg atcgttcatc aactctcccg gtgtcgcggg gtggtgccgg
    25381 gtgcgccggt acgatcagga cccttccgcc gcggcggccg cggcgcaaga aggcgggcat
    25441 ggactctcgg cgcgggcctc ttggactttt ccgcccgccg cggactcacg gccggggcgt
    25501 tccggccgcc tgcaggatcc gtgccgtgta cgggttgagc tcgacgggtt cgtcctcgcc
    25561 gacgatgacc gtgccgccga ggtaggcgag gtggcgcccg cagacgaagt tgggttcgag
    25621 ggcgaaggtc atcccgggcg cgagttccat gtcgccgcag agggtggggt ggcgggcctc
    25681 gggcggatag gccccggcac cgggcagatg ctcggcggcg tacgagggga agccgctcag
    25741 cgcgatcatc gggttgaggg cgtgtatcgc cgggccgaac tcccagccgt cggcggcctc
    25801 caggggctcg cgcatggcgt cgacggcctc gccgaacgta cggccgggac gcagcgcccg
    25861 caggcacgcg tcgtagaccg cgcgggcgac gccggcggcg cgccgcaggt ccgggtgcgg
    25921 ctcgccgatg ctgatggtga cctggtgctg ggtgtggcgt ccggcgacgt tgctgaagac
    25981 ctcggcggag atgacatcgc cgtcccgcag ggtacgaggg gc
//
