LOCUS       NZ_CP031320            22316 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces armeniacus strain ATCC 15676 chromosome.
ACCESSION   NZ_CP031320
VERSION     NZ_CP031320.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces armeniacus
  ORGANISM  Streptomyces armeniacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Draft genome of the type strain Streptomyces armeniacus ATCC 15676
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2018) Department Of Chemistry and Biomolecular
            Sciences, University Of Ottawa, D'Iorio Hall, 10 Marie Curie,
            Ottawa, Ontario K1N 6N5, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUL-2018
            Assembly Method                   :: SPAdes v. JULY-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003355155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:13:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,031
            CDSs (total)                      :: 6,963
            Genes (coding)                    :: 6,742
            CDSs (with protein)               :: 6,742
            Genes (RNA)                       :: 68
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 36 of 221
            Pseudo Genes (incomplete)         :: 204 of 221
            Pseudo Genes (internal stop)      :: 5 of 221
            Pseudo Genes (multiple problems)  :: 22 of 221
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:36:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6846061
            Orig. end                         :: 6868377
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031320.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22316
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22316
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22316
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12316](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12316
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(601..1269)
                     /locus_tag="DVA86_RS29875"
                     /old_locus_tag="DVA86_30090"
     CDS             complement(601..1269)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015038135.1"
                     /locus_tag="DVA86_RS29875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30090"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_208883005.1"
                     /transl_table=11
                     /translation="MFDFLDQYDVWEAFWVTIKLTLYSAIGSLIWGTLLAAMRVSPVPV
                     MRAFGTLYINTVRNTPLTVIIVATSLGLYQTLGIELGGGTSKDINFKLAVLGLIVYHAS
                     FVCESLRSGINTVPVGQAEAARALGLNFIQVLTLIVLPQAFRSVVAPLANVLIALTKNT
                     TVAAAIGVAEAALLMKEMVENESDVIFLVFAVFAFGFIVLTLPVGLLLGWVSKRVAVKR
                     "
     gene            complement(1349..2176)
                     /locus_tag="DVA86_RS29880"
                     /old_locus_tag="DVA86_30095"
     CDS             complement(1349..2176)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007266962.1"
                     /locus_tag="DVA86_RS29880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30095"
                     /product="glutamate ABC transporter substrate-binding
                     protein"
                     /protein_id="WP_208883007.1"
                     /transl_table=11
                     /translation="MNLRKASMAAAAALTLALTATACGGGGSGDDDGLTIGIKFDQPGL
                     GLKTPDGKYEGFDVDVAKYIAKEMGVKEADITWKEAPSAERENLISNGDVDFIAATYSI
                     TPERKEKVDFAGPYLMAHQDLLVRKDDNSIKSEKDLNTSDLKLCSVTGSTSAQNVKKEF
                     APKADLQEYGGYSECLTGLENKAADALTTDDSILAGFASQKEHQGKFRLAGLNLSDEPY
                     GVGLKKGDTKLQKQINDAITKMVKDGSWEKAAEKHFGPADYQYDKAPKITETS"
     gene            complement(2226..3011)
                     /locus_tag="DVA86_RS29885"
                     /old_locus_tag="DVA86_30100"
     CDS             complement(2226..3011)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359928.1"
                     /locus_tag="DVA86_RS29885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30100"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_208883009.1"
                     /transl_table=11
                     /translation="MSKVSVTKDAGGPESAPSGLVVLDNVNKHFGALHVLQDIDLTIAR
                     GEVVVVIGPSGSGKSTLCRTINRLETIDSGYIAVDDKPLPAEGKELARLRADVGMVFQA
                     FNLFAHKTVLDNVMLGQLKVRKTDKEEAEKKARALLDRVGVANQADKYPAQLSGGQQQR
                     VAIARALAMDPKVMLFDEPTSALDPEMINEVLEVMQQLARDGMTMVVVTHEMGFARSAA
                     NRVVFMADGRIVEEATPDQFFSNPRSDRAKDFLSKILHH"
     misc_feature    3090..3105
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.54"
                     /tool="antismash"
     gene            3312..4034
                     /locus_tag="DVA86_RS29890"
                     /old_locus_tag="DVA86_30105"
     CDS             3312..4034
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005311114.1"
                     /locus_tag="DVA86_RS29890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30105"
                     /product="response regulator transcription factor"
                     /protein_id="WP_208883011.1"
                     /transl_table=11
                     /translation="MRLLLVEDDERVAAALSAVLERHGFTVVHARDGEDALRELLPGDD
                     AAPFGVVLLDLGLPGQDGFEVCGRIRKLTSVPVIMVTARADVRSRIHGLNLGADDYVVK
                     PYDTGELLARIHAVSRRTVPADEAGAEEQGTGGAAGGAVLRLGKLTIELPTRQVSVGGR
                     AVSLTRKEFDLLALLAQRPGVVFRREQIISEVWRTSWEGTGRTLEVHVASLRSKLGLPA
                     LIETVRGVGYRLVAPPAA"
     gene            4058..5479
                     /locus_tag="DVA86_RS29895"
                     /old_locus_tag="DVA86_30110"
     CDS             4058..5479
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016470229.1"
                     /locus_tag="DVA86_RS29895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30110"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_208883013.1"
                     /transl_table=11
                     /translation="MRARLLPLLILLFAGVPLALGLPLAVSLASAEQQNVVVDRIDDTA
                     RFASLAQFVTARSEQGERLATLRRELRRYHDLYGIRAGVFYRDGQTMAAAPDGWRVPRT
                     GAGQEAFMEALAGRRSHDPKQVWPWQRGRIAVASPVIRDGDVAAVVYTDSPTGQLRSRI
                     LHGWLPIAAGEAAALLLAVAAAFLLTRWVLRPVRTLDWAAHEIATGEFKSRVAASGGPP
                     ELRRLARSFNEMADHVEDVLEQQRAFVADASHQLRNPLSALLLRIELLGLELPEGNEEV
                     ASVRAEGKRLAQVLDDLLDLALAEHSAADLRLTDVAALAAERVAAWQPVAEQDGVELRY
                     EGAPAVTGWADPVALSSALDAVVDNAVKFTPAGQRVTVTAAAGGDEATVEVADGGPGLD
                     EEELARVGDRFWRSSRHQNVSGSGLGLSITRALLSAGGARVGFAPNEPHGLRVTLTLPR
                     DEPPAPAGDAESPAR"
     gene            complement(5513..8560)
                     /locus_tag="DVA86_RS29900"
                     /old_locus_tag="DVA86_30115"
     CDS             complement(5513..8560)
                     /GO_function="GO:0004559 - alpha-mannosidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006013 - mannose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547264.1"
                     /locus_tag="DVA86_RS29900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30115"
                     /product="glycoside hydrolase family 38 C-terminal
                     domain-containing protein"
                     /protein_id="WP_208883015.1"
                     /transl_table=11
                     /translation="MHDDHSIVEDRLRRVLDERVRPAVYTSPLPLTVERWDAPDEPVPV
                     SEGLGAPYGPGAAGEEWGPAWGTTWFRVTGQVPAEWAGKTVEAVLDLGFDRRMPGFQCE
                     GLVYRADGEAVKALNPFNDWVRIGQPAAGGEAVELYVEAAANPILNTPQTPTYEGDRLT
                     AGDHPLYRLGRMDLAVFETEVWELVQDLEVTGGLMRELPLDDARRWELLRALERALDAL
                     DLTDVPGTAERARACLTGVLAAPARASAHRISAVGHAHIDSAWLWPLRETVRKVARTAS
                     NMVSLMDDHPEFVFAMSQAQQLAWIKEHRPEVYARVKKKVADGQFVPVGGMWVESDTNM
                     VGGEAMARQFLYGKKFFLDEFGVDTKEVWLPDTFGYTAAMPQIVSLAGAKWFLTQKISW
                     SQTNEFPHHTFWWEGIDGTRVFTHFPPVDTYNSELSGAEMAHAARNYREKGAGSRSLAP
                     FGHGDGGGGTTREMLARAERLRDLEGSPRVTVEKPAAFFEKAHEEYQDAPVWAGELYLE
                     LHRGTYTSQAKTKQGNRHSESLLREAELWAATAALRVPGQAYPYEQLEQLWKTVLLHQF
                     HDILPGSSIAWVHREARETYARVRAELEGIIERAQRALAGEGSAPMVFNGAPHARGGVP
                     GGGAAARTRTAEGETVTVAERDGGGWVLANGLLRVEIDDRGLVVSAYDAVGDRESVAPG
                     HAANLLQVHPDFPNHWDAWDVDEFYRHNVTDLTGADEVAVTSDGPDAVTVRAARSFGSS
                     SVVQQLTLRAGARSLDIDTEVDWQETEKFLKAAFPLDVKAERSASETQFGHVFRATHTN
                     TSWEAAKFEICAHRWLQVEEPDWGVALVNDSTYGHDVTRDVRPDGGQTTTVRLSLLRAP
                     RYPDPETDQGRHRLRYALVPGATVGDAVREGHWINLPERTVEGGGDPVAPLIAVAGDQV
                     VAEAVKLAEDRSGDVIVRLYESRGSRARTTVTAGFTLASAAVVDLLERPLTDAYALAEP
                     EAAADGAVEVSLRPFQILTLRLTPAG"
     gene            complement(8674..9705)
                     /locus_tag="DVA86_RS29905"
                     /old_locus_tag="DVA86_30120"
     CDS             complement(8674..9705)
                     /GO_function="GO:0005215 - transporter activity [Evidence
                     IEA]"
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602701.1"
                     /locus_tag="DVA86_RS29905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30120"
                     /product="TAXI family TRAP transporter solute-binding
                     subunit"
                     /protein_id="WP_208883016.1"
                     /transl_table=11
                     /translation="MVRPGVPYGLRDGARAVRALTRRRVVRGACAALVVLGLLAWWLLP
                     GGSPAPSGNVTFATGVPTGVYARYGTLLQQRLGRDAPDLDMGLKASEGSVENIEMVVSG
                     EADFTIAQSDAVADYVDGGGEGADRLSACARLYDDYVQLIVPADSPVRSARDLKGLRVG
                     MGEERSGVSLVAGRLLQAAGLNRKKDLHEVPIGIDRMPALLADGKLDAFLWTGGLPTTA
                     IEQLAEKTRIRLVQLGDLVPRLQRMEPETRHYRPAVMPADAYPAVQQGEPVNTVAVSNL
                     LVTTDRTDAEVAEALTRSLINSRDQIGNEVHAAQKVDLRTAIYTDPLPLHEGAERYYRA
                     VKP"
     gene            10001..12316
                     /locus_tag="DVA86_RS29910"
                     /old_locus_tag="DVA86_30125"
     CDS             10001..12316
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383771.1"
                     /locus_tag="DVA86_RS29910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30125"
                     /product="terpene synthase family protein"
                     /protein_id="WP_208883018.1"
                     /sec_met_domain="T1TS (E-value: 2.1e-84, bitscore: 283.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQPFELPDFYTPYPARLNPHTAEARTHSRDWAREMGMLEGSGVW
                     EQSDLDAHDYALLCAYTHPDASGPDLSLVTDWYVWVFFFDDHFLEVFKKPQDREGARTY
                     LDRLPAFMPMDLDDGIPEPANPVEAGLADLWARTVPEMSAAWRARFAESTRNLLNESLW
                     ELANIHARRVPNPVEYIEMRRKVGGAPWSAGLVEYAARAEVPAAVAGSRPLRVLRDSFS
                     DAVHLRNDLFSYQRETEEEGELANGVLVLETFLGCTTQQAADAVNDLLTSRLQQFEHTV
                     FTELGPLFAETGLDAPSSASVMAYVKGLQDWQSGGHEWHMRSSRYMNSRSAHGGTDSGT
                     DAGAPFAAPLGLSGLTARGLGTAAAGLAATRLTTARAEAARARTFRYMPYQRVGPSQLP
                     PIDMPFTARLSPHLGAARRNVVDWSRRMGFLEPQPGVPHSHVWDEELLRDHDLPLCAAG
                     IHPDATPDELDLSSDWLAWGTYGDDYYPVVFGRQRDLAGARVCTERLRAFMPLESEPVP
                     PPANALERGLADLWTRTAGPMAAAARRALRKAVEDMTDSWLWELGNQAQNRVPDPVDYI
                     EMRRLTFGSDLTMSLCRLAHGERLPPEIHGSRPMRSLENAASDYACLVNDVFSYQKEIE
                     FEGEVHNGVLVVQHFFDCDRPTAVAVIGDLMSSRMRQFQHVVAHELPVLHDEFSLDAVA
                     VAALDDYVRDLENWLSGILTWHQGCRRYTEDDLRRHAAAPPAAGGGGGPSAYALPTGLG
                     TSAARLARTAASARGGAG"
     misc_feature    complement(10002..10017)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.81"
                     /tool="antismash"
     gene            12430..13941
                     /gene="miaB"
                     /locus_tag="DVA86_RS29915"
                     /old_locus_tag="DVA86_30130"
     CDS             12430..13941
                     /EC_number="2.8.4.3"
                     /GO_function="GO:0016782 - transferase activity,
                     transferring sulphur-containing groups [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="miaB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277: Radical SAM
                     domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005311108.1"
                     /locus_tag="DVA86_RS29915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30130"
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="WP_208883019.1"
                     /sec_met_domain="PF04055 (E-value: 4.6e-33, bitscore:
                     113.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAQDTFTRSYEIRTFGCQMNVHDSERMAGLLEDAGYVRAPADGD
                     GADVVVFNTCAVRENADNRLYGNLGQLAPKKAAHPGMQIAVGGCLAQKDRDTIVRKAPW
                     VDVVFGTHNVGKLPVLLERARVQEEAQVEIAESLEAFPSTLPTRRESAYAAWVSVSVGC
                     NNTCTFCIVPQLRGKEKDRRPGDILAEVEALVDEGVSEITLLGQNVNAYGSDIGDREAF
                     GKLLRACGRIEGLERVRFTSPHPRDFTDDVIAAMAETPNVMPQLHMPLQSGSSRVLKAM
                     RRSYRQERYLEIIEKVRAAMPDAAISTDIIVGFPGETEEDFQETLHVVREARFAQAFTF
                     QYSKRPGTPAAEMDGQLPKAVVQERYERLVELQEEISWAENKKQLGRTVEVMAAEGEGR
                     KDGATRRLSGRATDNRLVHFTPGEDAVRPGDLATVEITYAAPHHLLAEGPARSVRRTRA
                     GDAWERRNSAPQEPGSGSGVLLGLPTVGAPEPQPAATGTGSCGSC"
     gene            14014..14727
                     /locus_tag="DVA86_RS29920"
                     /old_locus_tag="DVA86_30135"
     CDS             14014..14727
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520784.1"
                     /locus_tag="DVA86_RS29920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30135"
                     /product="class III extradiol dioxygenase subunit B-like
                     domain-containing protein"
                     /protein_id="WP_208883021.1"
                     /transl_table=11
                     /translation="MLVAAAVCPCPPLLVPEVAGAAAPEMDGARAACYDAIGVLAAARP
                     DRLVVVGPAEQPGRGPHPQGAPGSFRGFGADIEVTLGKGDPAPGARDLPPSLAVGAWLL
                     DRTDWSSAPLEGLGVGEPLTRDRCTAAGRELAASARRVALLVMGDGSACRTLKAPGYFD
                     ERAAAFDAEAARALGEADLDGLLALDEELAYELKAAGRACWQVLAGAGEGAGLSGRLLY
                     DEAPYGVGYLVAGWS"
     gene            complement(14859..15071)
                     /locus_tag="DVA86_RS29925"
                     /old_locus_tag="DVA86_30140"
     CDS             complement(14859..15071)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359936.1"
                     /locus_tag="DVA86_RS29925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30140"
                     /product="antitoxin"
                     /protein_id="WP_208883022.1"
                     /transl_table=11
                     /translation="MGFMDKVKGMLGQHSDKAGQGMDKGADTLNEKTGGKHSDKIQSGT
                     DKAKDSMDRMGDDTRGGERGGSDAA"
     misc_feature    15164..15177
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.23"
                     /tool="antismash"
     gene            15323..16273
                     /gene="miaA"
                     /locus_tag="DVA86_RS29930"
                     /old_locus_tag="DVA86_30145"
     CDS             15323..16273
                     /EC_number="2.5.1.75"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0052381 - tRNA dimethylallyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006400 - tRNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="miaA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IPPT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072889.1"
                     /locus_tag="DVA86_RS29930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30145"
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="WP_208883023.1"
                     /sec_met_domain="IPPT (E-value: 2.8e-83, bitscore: 278.0,
                     seeds: 863, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVPVSAFRPAPQVIAVVGPTAAGKSDLAVSLARQLGGEVVNADS
                     MQLYQGMDIGTAKLTAEERQGVPHHLLDIWHVTVAASVAEYQRLARAEIDRLLAAGRVP
                     VLVGGSGLYVRGVIDVMEFPGTDPAVRARLEAELAEHGTRALHARLAAADPDAARAILP
                     SNGRRVVRALEVIEITGRPFTANLPGHEAAYDTLQIGVDVARPELDERIADRVDRMWRA
                     GLVDEVRALEEVGLRQGRTASRALGYQQVLAALAGECTEDEARAETVRATKRFARRQDS
                     WFRRDPRVHWLSGAASDRGELTASALTLLERAVTA"
     gene            16381..16848
                     /locus_tag="DVA86_RS29935"
                     /old_locus_tag="DVA86_30150"
     CDS             16381..16848
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385150.1"
                     /locus_tag="DVA86_RS29935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30150"
                     /product="hypothetical protein"
                     /protein_id="WP_245997778.1"
                     /transl_table=11
                     /translation="MEASPRDNEESRVDYVSDGDVGRPGVDDDLAAVAGVDGPVGPPVE
                     PHELRPQRRLRLWQLAPIVVLGALGSLMFAFPLAFEPGSRSGAVVSMLGLLICCCAAGW
                     GVMAARRVGHTWPGLPSPGSGKRADWRVVLLYAVVVGTVAVLAVWRVARLS"
     gene            16951..17820
                     /gene="dapF"
                     /locus_tag="DVA86_RS29940"
                     /old_locus_tag="DVA86_30155"
     CDS             16951..17820
                     /EC_number="5.1.1.7"
                     /GO_function="GO:0008837 - diaminopimelate epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019547271.1"
                     /locus_tag="DVA86_RS29940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30155"
                     /product="diaminopimelate epimerase"
                     /protein_id="WP_208883026.1"
                     /transl_table=11
                     /translation="MSSARPVPFLKGHGTENDFVIIPDPDGEFELSKEAVARLCDRRAG
                     IGGDGLLRAVRSARHPEARGMAGEAEWFMDYRNSDGSIAEMCGNGVRVFARHLVRAGLA
                     PAGELAVATRAGIRRVRLAADGGGVTVGMGRAALPAGDVRVTVGDRTWPARHVNVGNPH
                     AVAFVDDLAAAGPLREAPGVAPAAAYPQGVNVEFVVDRGPRHVALRVYERGSGETRSCG
                     TGACAVMVAAARRDGADPSADGNPVTYTVDVPGGRLVISEGTDGGIEMTGPAVIVAEGM
                     LDPDLLAV"
     misc_feature    complement(17847..17860)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.76"
                     /tool="antismash"
     gene            18009..19817
                     /locus_tag="DVA86_RS29945"
                     /old_locus_tag="DVA86_30160"
     CDS             18009..19817
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018538241.1"
                     /locus_tag="DVA86_RS29945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30160"
                     /product="HD domain-containing protein"
                     /protein_id="WP_208883028.1"
                     /transl_table=11
                     /translation="MGAVRNLRKLSRAALLRPAPRGALPDAIEHVAQAHRAHHPGADLD
                     ALRRAYLLAESSHRGQTRKSGEPYITHPLAVTLILAQLGAEHTTLTASLLHDTVEDTDV
                     TLDQVRAEFGDEVCHLVDGVTKLEKVDYGAAAEPETFRKMLVATGSDVRVMSIKLADRL
                     HNMRTLGVMRPEKQARIAKVTSDVLIPLAERLGVQALKRELEDLVFAILLPEEHARTQE
                     LIREHTARPDPLTQVAATVRAVLREAEIDAQVLIRPRHLVSLHRLRLKRGELGPCDFGR
                     LMILVAEDADCYAALGELHTCFVPVMSEFKDFIAVPKFNLYQSLHTAFADKDGRVAEVL
                     VRTRQMHQVAEAGVIALGDPHSAPAEAEAEAGGDGERADPTRPGWLSRLLEWQSHTTDP
                     DTFWSELRDELAEDREITVYCAEPGTGGSSGALPLPAGASCVDAAYALHGEAAHRCIGA
                     RVNGRLTALSTVLRDADTVQLFLAPTTGTAAYAPAPEWLDHARTPAARIAIRKWLAAHP
                     PVPAADTVTAPAEHGTDARPAPRRDARPEPVAESRTHAPATSPSSAPASPKHAVLALAR
                     RRVNVLFAMIRDRQCYHAPPSVTTAA"
     misc_feature    18288..18290
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19905..20924
                     /locus_tag="DVA86_RS29950"
                     /old_locus_tag="DVA86_30165"
     CDS             19905..20924
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (61-187). E-value:
                     3.1e-11. Score: 35.3. Matches aSDomain:
                     nrpspksdomains_DVA86_RS29950_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030711.1"
                     /locus_tag="DVA86_RS29950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30165"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_208883029.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.8e-15, bitscore:
                     54.7, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.4e-07, bitscore: 30.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGDSYGGRVTRRIALRNAGIVAGGAALAAGTGAGTGAASAAVRG
                     APHGGGRPRHGTVRTYVLVHGTHSAGAYWTPIARELTLRGHRVVAVDQPLHGAEAFVPE
                     AYQTQDLRALATEPSPVARLGLDDYARRVEQAVRRAAEHGPLVLVAHSMGGISVTRTGN
                     AVPELIDHICYMASFCPSRSMPTLNDCMSAPESASAVSTDEQVVGDMERLGVARFNWRT
                     GRRKDLDVFKEMICADHPDDAFRRVIAGMQTDETLRAYGERAVGERDTWGRVPRTYLRF
                     GRDRLVTPELQDRMINEADRLTPGNQFTVHDFTRAPHIGPLDPAPVVDALEGVAVRRR"
     aSDomain        20088..20465
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVA86_RS29950_Abhydrolase_1.1"
                     /evalue="3.10E-11"
                     /label="DVA86_RS29950_Abhydrolase_1.1"
                     /locus_tag="DVA86_RS29950"
                     /protein_end="187"
                     /protein_start="61"
                     /score="35.3"
                     /tool="antismash"
                     /translation="VLVHGTHSAGAYWTPIARELTLRGHRVVAVDQPLHGAEAFVPEAY
                     QTQDLRALATEPSPVARLGLDDYARRVEQAVRRAAEHGPLVLVAHSMGGISVTRTGNAV
                     PELIDHICYMASFCPSRSMPTL"
     gene            complement(21014..21784)
                     /locus_tag="DVA86_RS29955"
                     /old_locus_tag="DVA86_30170"
     CDS             complement(21014..21784)
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007825925.1"
                     /locus_tag="DVA86_RS29955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_30170"
                     /product="serine hydrolase"
                     /protein_id="WP_245997345.1"
                     /transl_table=11
                     /translation="MAWFAGTAAPAPDAVLAAALRGLARTAEGNVSLAIGDPASGSSAV
                     YAPPDEHAFVTASVAKVGILAALLLRAQKEGRPLTAEQRTDARQMIQVSDNHAADRLWR
                     AIGGADGLAEANRTFGLTGTVPGADDHWGLTTTTAADQLRLLTAVTAADSPLTPESRAY
                     VRALMSRVRSGQDWGVSAAADPGTGTALKNGWLPRTASGLWVVNSVGVVRHDGHELLLA
                     VLCDGQPSQATGIDTVEAAVVAAAEAVTGVLVGR"
ORIGIN
        1 ccgggagcat cgcggtgacg gcctgcggca gcagcacgta cgacatgagc tggcccttgc
       61 gcatgccgat ggccttggcc gcgtctgtct ggcctgccgg aagggactgg atgcccgccc
      121 gtacgatctc ggcgatgacg gcgctgttgt acagcacgag gccggtcacc accgcgtaca
      181 gcgggcggac ttcgggctcg agggtgctga actccgcgta cgcctggttc gcgaacacca
      241 tcatcagcag cacggggatg gcgcggaaca gctccacgac ggcgcccgcg gggatgctga
      301 cccacttgtg gtcggagagc cgtccgatgc cgaggatcgc gccgagcggc agcgcgatgg
      361 cgatcgagag gcccgccgcc ttcagggtgt tgagcaggcc cgggaagaga tacgtcgtcc
      421 acacccggga gtcggtgaag aacggcttcc acttctcccc ggccagctgg tccttgtccg
      481 ccatctcgcc caggacccac cacgcggcga gtacgaagac cacgaggaac aggacggagt
      541 agagccagtt gcgcaccttg gcgcgcggcc cgggggcgtc gtacagaaca gagaggtcac
      601 tcatcgcttc accgccacgc gcttgctgac ccagcccagg aggaggccga ccggaagtgt
      661 gagaacgatg aacccgaagg cgaacaccgc gaagaccagg aagatgacgt cactctcgtt
      721 ctccaccatt tccttcatca gcagcgccgc ctcggcgacg ccgatggccg ccgccacggt
      781 ggtgttcttg gtgagggcga tcagtacgtt cgcgagcggc gccaccacgg agcggaacgc
      841 ctgcgggagg acgatgagcg tcagcacctg gatgaagttc aggcccagtg cgcgcgccgc
      901 ctccgcctgg ccgaccggca ccgtgttgat cccggagcgc agcgactcgc agacgaagct
      961 ggcgtggtac acgatcagac cgaggacggc cagcttgaag ttgatgtcct tcgaggtgcc
     1021 gccgccgagc tcgatgccca gcgtctggta gagccccagc gacgtggcga cgatgatcac
     1081 cgtgagcggg gtgttccgca cggtgttgat gtagagggtg ccgaacgcgc gcatcaccgg
     1141 caccgggctt acccgcatgg cggcgaggag ggtgccccag atcagggagc ctatcgccga
     1201 gtacagggtg agcttgatcg tcacccagaa cgcttcccac acgtcgtact gatcaagaaa
     1261 gtcgaacacg ttctcccgcg ctctcgcctc gttggatggg agtggcgcgc cgtccttccc
     1321 ggacggcgcg ccaccctgcc atcagctgtc agctggtttc cgtgatcttc ggtgccttgt
     1381 cgtactggta gtcggcgggg ccgaagtgct tctccgccgc cttctcccag gaaccgtcct
     1441 tgaccatctt ggtgatcgcg tcgttgatct gcttctgcag cttggtgtcg cccttcttga
     1501 ggccgacgcc gtacggctcg tcgctcaggt tgagcccggc gagcctgaac ttgccctggt
     1561 gctccttctg cgaggcgaag ccggcgagga tggagtcgtc ggtggtcagg gcgtcggcgg
     1621 ccttgttctc caggccggtg aggcactccg agtagccgcc gtactcctgc aggtccgcct
     1681 tcggcgcgaa ctccttcttg acgttctgcg cggaggtcga gccggtgacc gaacacagct
     1741 tcagatcgct ggtgttcagg tccttctcgc tcttgatgga gttgtcgtcc ttgcggacca
     1801 gcaggtcctg gtgcgccatc aggtacgggc cggcgaagtc gaccttctcc ttgcgctccg
     1861 gggtgatgga gtacgtggcg gcgatgaagt ccacgtcgcc gttcgagatc aggttctcgc
     1921 gctcggcgct gggggcttcc ttccaggtga tgtccgcctc tttgacgccc atctccttgg
     1981 cgatgtactt cgccacgtcg acgtcgaagc cctcgtactt gccgtccgga gtcttcagcc
     2041 ccagccccgg ctggtcgaac ttgatgccga tggtcagtcc gtcgtcgtcg cctgagccgc
     2101 cgccaccgca cgcggtggcg gtcagtgcga gggtgagcgc ggcggccgcc gccatgctgg
     2161 ctttgcggag attcatggtg agcttccctg tgatcgttgt tgtccgtggt tccggtgagc
     2221 cgagctcagt ggtgaaggat cttcgacagg aagtccttcg cccggtcgct gcgcgggttg
     2281 ctgaagaact ggtcgggggt agcctcctcg acaattcgcc cgtccgccat gaaaaccacc
     2341 cggttggcag cggatcgtgc gaagcccatc tcgtgggtga cgacgaccat cgtcatcccg
     2401 tcccgcgcca actgctgcat gacctcgagg acctcgttga tcatctcggg gtcgagcgcc
     2461 gaagtcggct cgtcgaacag catcaccttg ggatccatgg ccagcgcgcg ggcgatggcc
     2521 acgcgctgct gctggccgcc ggagagctga gcggggtact tgtcggcctg gttcgcgaca
     2581 cccacccggt ccagcagggc gcgcgccttc ttctcggcct cctccttgtc cgtcttgcgg
     2641 accttcagct ggccgagcat gacgttgtcg agcaccgtct tgtgcgcgaa gaggttgaac
     2701 gcctggaaca ccatgcccac gtccgcgcgc agcctggcca gttccttgcc ttccgcgggc
     2761 aggggcttgt cgtcgacggc gatgtagccg gagtcgatcg tctccagccg gttgatcgtg
     2821 cggcacagcg tggacttgcc ggaaccggac ggtccgatga cgaccacgac ctcgccgcgc
     2881 gcgatcgtca ggtcgatgtc ctggagcacg tgcagcgcac cgaagtgctt gttgacgttg
     2941 tccaggacga ccaggccgct cggcgccgat tccggtccgc cggcgtcctt ggtcaccgat
     3001 actttgctca tcggcctgca gctccgtcct cgtcggttgc gaggacccta gtgagccccc
     3061 gccaccagcg tcattacatc tgaggggaaa ttgagcataa cgatctggtc gcagcgcggc
     3121 acactcggtg agccgggcgt gcggaggcgc cgcggggcgc gtaccggctg cataacggaa
     3181 agcgcggggc acccgtggcc ccttgactcg tctgggccga tccgcgtgga tgcagtgccg
     3241 gaccgcgtgc cgtaccggga ccggtccgcg tgccgggcag aagatcgaca gggccggaag
     3301 ggagggcacg tatgagactg ctgctggtcg aggacgacga gcgggtcgcc gccgcgctct
     3361 ccgcggtgct ggagcggcac ggcttcaccg tcgtgcacgc ccgggacggc gaggacgccc
     3421 tgcgggagct gctgcccggc gacgacgcgg cgcccttcgg cgtggtgctg ctcgacctcg
     3481 gactgccggg ccaggacggc ttcgaggtgt gcggacgcat ccgcaagctg acctccgtac
     3541 ccgtgatcat ggtgacggcc cgtgcggacg tacggtcgcg gatccacggt ctgaacctcg
     3601 gcgccgacga ctacgtcgtc aagccctacg acaccggcga gctcctcgcc cgtatccacg
     3661 cggtcagccg gcgcaccgtg cccgccgacg aggccggcgc ggaggagcag ggtacgggcg
     3721 gcgccgcggg cggcgcggtg ctgcggctcg ggaagctgac gatcgagctg cccacccgcc
     3781 aggtgtcggt gggcggccgt gcggtgtcgc tgacccgcaa ggagttcgac ctgctggcgc
     3841 tgctcgcgca gcggcccggg gtggtgttcc ggcgggagca gatcatcagc gaggtgtggc
     3901 gtacgagttg ggaggggacc gggcggacgc tggaggtgca tgtggcgtcg ctgcgttcga
     3961 agctcgggct gcccgcgctc atcgagaccg tacggggcgt cggctaccgg ctcgtcgcgc
     4021 cgccggccgc gtagccacgg accgccggac cgatcgcgtg cgcgcccgcc tcctcccgct
     4081 cctcatcctc ctgttcgccg gggtgcccct cgccctcgga ctgccgctcg cggtcagcct
     4141 ggcctcggcc gagcagcaga acgtcgtcgt ggaccgcatc gacgacaccg cgcggttcgc
     4201 gtcgctcgcg cagttcgtca ccgcgcgcag cgagcagggc gagcggctgg ccacgctccg
     4261 ccgcgaactg cgccgctacc acgacctgta cggcatccgc gccggcgtct tctaccgcga
     4321 cgggcagacc atggccgccg cccccgacgg ctggcgggtg ccgcgtacgg gcgcgggcca
     4381 ggaggcgttc atggaggcgc tggccgggcg gcgcagccac gacccgaagc aggtgtggcc
     4441 gtggcagcgg ggccgtatcg ccgtcgcctc gccggtgatc agggacggcg acgtggccgc
     4501 cgtcgtctac accgactcgc ccaccgggca gctgcgctcc cgcatcctgc acggctggct
     4561 gccgatcgcg gccggcgagg ccgcggcgct gctgctcgcg gtggcggcgg cgttcctgct
     4621 gacgcgctgg gtgctgcggc cggtgcgcac gctggactgg gccgcgcacg agatcgccac
     4681 cggcgagttc aagtcccgtg tcgccgcctc cggtggcccg cccgaactgc gccgcctcgc
     4741 gcggtcgttc aacgagatgg ccgaccacgt ggaggatgtg ctggagcagc agcgcgcctt
     4801 cgtggccgac gcctcgcacc agctgcggaa cccgctgtcc gcgctgctgc tgcggatcga
     4861 gctgctcggg ctcgagctgc cggagggcaa cgaggaggtc gcgtccgtac gggcggaggg
     4921 caagcggctc gcacaggtgc tggacgacct gctggacctg gcgctggccg agcactccgc
     4981 ggcggacctg cggctgaccg acgtcgcggc gctggccgcc gaacgcgtcg cggcctggca
     5041 gccggtcgcg gagcaggacg gtgtggagct gcgctacgag ggcgcgccgg cggtcaccgg
     5101 gtgggccgac ccggtggcgc tgtccagcgc gctggacgcg gtggtcgaca acgcggtcaa
     5161 gttcacgccg gcggggcagc gggtgaccgt cacggccgcc gcgggcgggg acgaggcgac
     5221 ggtggaggtc gcggacggcg gcccggggct ggacgaggag gaactcgccc gcgtcggcga
     5281 ccgcttctgg cgcagcagcc gccaccagaa cgtgtccggc tcgggcctcg gactgtccat
     5341 cacccgcgcg ctgctctccg cgggcggcgc gcgcgtcggc ttcgcgccga acgagccgca
     5401 cggcctgcgc gtcaccctca ccctgccacg cgacgagccc cccgcaccgg ccggggacgc
     5461 ggagtccccg gcgcggtgac gaggggctcg tcgccactcg gtaccggggc cgtcagcccg
     5521 ccggtgtgag ccgcagggtg aggatctgga acgggcgcag cgacacctcc accgcgccgt
     5581 ccgccgccgc ctccggctcc gcgagcgcgt acgcgtccgt gagcggccgc tccagcaggt
     5641 ccaccacggc cgccgaggcg agcgtgaagc ccgccgtgac ggtcgtacgg gcgcggctgc
     5701 cgcgggactc gtagagccgt acgatcacgt cgccgctgcg gtcctccgcc agcttgacgg
     5761 cctccgccac gacctggtcg cccgcgacgg cgatgagcgg cgcgacgggg tcgccgccgc
     5821 cctccacggt gcgctccggc aggttgatcc agtggccttc gcggaccgcg tcgcccaccg
     5881 tcgcgcccgg caccagcgcg tagcgcagcc ggtgcctgcc ctggtccgtc tccgggtcgg
     5941 ggtagcgcgg cgcgcgcagc agggacagcc ggaccgtggt ggtctggccg ccgtcggggc
     6001 gtacgtcgcg ggtgacgtcg tgcccgtacg tcgagtcgtt gacgagggcg acgccccagt
     6061 ccggctcctc gacctgcagc cagcggtgcg cgcagatctc gaacttggcc gcctcccagg
     6121 aggtgttggt gtgcgtcgcg cggaagacgt gcccgaactg cgtctccgac gccgaccgtt
     6181 cggccttcac atccagcggg aacgcggcct tgaggaactt ctcggtctcc tgccagtcca
     6241 cctcggtgtc gatgtccagc gagcgcgcgc cggcgcgcag cgtcagctgc tgcacgacgg
     6301 aggaggagcc gaacgagcgg gcggcccgta cggtcacggc gtccggcccg tcggaggtca
     6361 ccgccacctc gtcggcgccg gtcaggtccg tgacgttgtg ccggtagaac tcgtccacgt
     6421 cccaggcgtc ccagtggttc gggaagtccg ggtgcacctg gaggaggttg gcggcgtgcc
     6481 ccggtgcgac cgactcgcgg tcgccgacgg cgtcgtatgc ggagaccacc aggccgcggt
     6541 cgtcgatctc cacgcgcagc aggccgttgg cgagcaccca gccgccgccg tcccgttccg
     6601 cgacggtgac ggtctcgccc tcggccgtac gcgtccgggc tgccgcgccg ccgccgggta
     6661 cgccgccgcg ggcgtgcggt gcgccgttga acaccatcgg cgcgctgccc tcgcccgcca
     6721 gcgcgcgctg ggcgcgctcg atgatgccct ccagctcggc gcgcacgcgg gcgtacgtct
     6781 cgcgcgcctc gcggtggacc cacgcgatgg acgagcccgg caggatgtcg tggaactggt
     6841 gcagcagcac cgtcttccac agctgctcca actgctcgta cgggtacgcc tgaccgggca
     6901 cgcgcagcgc cgccgtggcc gcccacagct ccgcctcgcg cagcagggac tcgctgtgcc
     6961 ggttgccctg cttggtcttc gcctgcgagg tgtacgtgcc gcggtgcagc tccagataga
     7021 gctcgccggc ccacacgggc gcgtcctggt actcctcgtg cgccttctcg aagaacgccg
     7081 ccggcttctc caccgtgacc cgcggcgagc cctccagatc gcgcagccgc tccgcgcgcg
     7141 ccagcatctc gcgggtggtg ccgccgccgc cgtcgccgtg cccgaagggc gcgagggagc
     7201 gcgaaccggc gcccttctca cggtagttgc gcgcggcgtg cgccatctcg gcgccgctca
     7261 gttccgagtt gtacgtgtcg accggcggga agtgggtgaa cacgcgggtg ccgtcgatgc
     7321 cctcccacca gaaggtgtgg tgcgggaact cgttcgtctg gctccacgag atcttctgcg
     7381 tcaggaacca cttcgcgccc gccagcgaca cgatctgcgg catggccgcc gtgtagccga
     7441 aggtgtccgg cagccacacc tccttggtgt cgacgccgaa ctcgtccagg aagaacttct
     7501 tgccgtacag gaactgccgg gccatggcct cgccgccgac catgttcgtg tccgactcca
     7561 cccacatgcc gcccaccggc acgaactgcc cgtccgccac cttcttcttg acccgggcgt
     7621 acacctcggg ccggtgctcc ttgatccagg ccagctgctg cgcctgggac atggcgaaga
     7681 cgaactccgg gtggtcgtcc atgaggctga ccatgttgga cgcggtgcgc gccaccttcc
     7741 gtacggtctc ccgcagcggc cacagccacg ccgagtcgat gtgggcgtgc cccaccgcgc
     7801 tgatccggtg cgcggacgcg cgggccggcg ccgcaaggac gccggtgagg caggcacgcg
     7861 cgcgttccgc ggtgccgggc acgtcggtca ggtccagggc gtccagggcg cgttcgaggg
     7921 cgcgcagcag ttcccagcgg cgcgcgtcgt ccagcgggag ctcccgcatc agcccgcccg
     7981 tgacctccag gtcctggacc agctcccaga cctcggtctc gaagacggcc aggtccatgc
     8041 ggcccagccg gtagagcggg tggtcgcctg cggtgagccg gtcgccctcg taggtgggcg
     8101 tctggggggt gttgaggatc gggttcgcgg ccgcctcgac gtacagctcc accgcctcgc
     8161 cgcccgcggc gggctgcccg atccgcaccc agtcgttgaa cgggttgagc gccttcaccg
     8221 cctcgccgtc cgcgcggtag acgaggccct cgcactgaaa gccgggcatc ctccggtcga
     8281 agcccaggtc gagcaccgcc tcgacggtct tccccgccca ctccgcgggc acttgtccgg
     8341 tgacccggaa ccaggtcgtg ccccaggccg gcccccactc ctcgccggcc gcaccgggac
     8401 cgtacggggc accgaggccc tcggacacgg gcacgggctc gtcgggcgcg tcccagcgct
     8461 cgacggtgag cggcagcggc gaggtgtaga cggcggggcg cacccgctcg tccaggacgc
     8521 ggcgcagtcg gtcttcgaca atgctgtggt cgtcgtgcat acggcgactc cttcgatggg
     8581 cgtcacggag cggacctccg acatcgatat cacccgctcc gacagggcgt cttccccatc
     8641 tcgcaggttg gttatcccgg cgccggcgtc cgctcagggc ttgaccgcgc ggtagtaccg
     8701 ttcggcgcct tcgtgcaggg gaagcgggtc ggtgtagatc gcggtgcgca ggtcgacctt
     8761 ctgggccgcg tgcacttcgt tgccgatctg gtcccggctg ttgatcagcg aacgcgtcag
     8821 ggcctccgcc acctccgcgt ccgtccggtc cgtggtgacc agcaggttcg acaccgcgac
     8881 cgtgttgacg ggctcgccct gctgtacggc cgggtacgcg tccgcgggca tcaccgccgg
     8941 gcggtagtgg cgcgtctcgg gctccatccg ctgcagccgc ggcaccaggt cgccgagttg
     9001 tacgagccgg atgcgggtct tctcggcgag ctgctcgatg gcggtggtgg gcagcccgcc
     9061 ggtccacagg aacgcgtcca gcttcccgtc cgccagcagc gcgggcatcc ggtcgatgcc
     9121 gatcggcacc tcgtgcaggt ccttcttccg gttcagcccg gcggcctgca gcagccgccc
     9181 cgcgaccagg ctcaccccgg aacgctcctc gcccatgccg acccgcagcc ccttcaggtc
     9241 gcgcgcgctg cgtacggggg agtcggcggg gacgatcagc tgcacgtagt cgtcgtacag
     9301 ccgggcgcac gcggacagcc ggtccgcgcc ctcgccgccg ccgtccacgt agtcggcgac
     9361 ggcgtccgac tgcgcgatcg tgaagtccgc ctcgccggag accaccatct cgatgttctc
     9421 cacggacccc tcgctggcct tgaggcccat gtcgaggtcc ggcgcgtcac ggccgagccg
     9481 ctgctgcagc agcgtgccgt agcgggcgta caccccggtg gggactccgg tggcgaacgt
     9541 gacgttcccg ctgggcgccg ggctgccgcc gggcagcagc caccacgcca gcagccccag
     9601 cacgaccaac gccgcgcacg cgccgcgcac cacgcgccgg cgcgtcagcg cgcgcacagc
     9661 gcgtgcgccg tcgcgcaagc cgtacggcac tccgggtctg accatgcgca cgatcctgcc
     9721 agtcgcggtg cgcggcaggc agccgtacgg agcggaacgg tgcgcggaac gcggtggtca
     9781 cgggtgcacc ctcggggctc acctggtacg ggagtggcct gaggcgactt ctgtgggtga
     9841 ccggcgccat ggccgaaatc cacgggtgat ttgtatgact gttccgccgc ccggatggcg
     9901 cccgcgggcc acgggtaagg ctcagcgcgt ccggggcggg cgcggccccg gcgacgccgc
     9961 ggaacgacag ctcagccgct tcgaggaaag gcccgggcac gtgacacagc ccttcgaact
    10021 gccggacttc tacactccgt atcccgcccg gctgaacccg cacaccgccg aggcgcggac
    10081 gcactcgagg gactgggccc gcgagatggg catgctggag ggctccggcg tgtgggagca
    10141 gagcgacctg gacgcgcatg actacgcgct gctctgcgcg tacacgcacc ccgacgcctc
    10201 gggtccggac ctgtcgctgg tcaccgactg gtacgtgtgg gtcttcttct tcgacgacca
    10261 cttcctggag gtcttcaaga agccgcagga ccgcgagggc gcccgtacgt atctggaccg
    10321 gctccccgcc ttcatgccga tggacctcga cgacggcatc cctgagcccg ccaaccccgt
    10381 tgaggcgggc ctcgccgacc tgtgggcccg tacggtgccc gagatgtccg cggcctggcg
    10441 ggcgcgcttc gcggagagca ccaggaacct gctgaacgag tccctgtggg agctcgcgaa
    10501 catccacgcg cgccgtgtcc cgaaccccgt cgagtacatc gagatgcgcc gcaaggtggg
    10561 cggcgccccc tggtcggccg ggctggtgga gtacgcggca cgcgccgagg tgccggccgc
    10621 cgtcgccggg tcgcggccgc tgcgggtgct ccgggacagc ttctcggacg cggtccacct
    10681 ccgcaacgac ctcttctcgt accagcggga gaccgaggag gagggcgaac tggccaacgg
    10741 cgtactggtc ctggagacct tcctcggctg taccactcag caggccgcgg acgccgtcaa
    10801 cgacctgctg acctcccggc tccagcagtt cgagcacacg gtgttcaccg aactgggccc
    10861 cctcttcgcc gagaccggcc tcgacgcgcc ctccagcgcg tccgtcatgg cgtacgtcaa
    10921 ggggctgcag gactggcagt cgggcggcca cgagtggcac atgcgctcca gccgctacat
    10981 gaacagccgc tccgcgcacg gcggtacgga cagcggtacg gacgcgggcg cccccttcgc
    11041 cgccccgctc gggctgtccg ggctcaccgc gcgcggcctc ggcacggccg ccgccgggct
    11101 ggcggcgacg cggctgacca ccgcgcgcgc ggaggccgcc cgcgcccgca ccttccggta
    11161 catgccgtac cagcgggtgg gcccgtccca actgcccccg atcgacatgc cgttcaccgc
    11221 ccgactcagc ccgcatctgg gcgccgcccg ccggaacgtc gtcgactggt cgcgccgcat
    11281 gggcttcctg gagccgcagc ccggcgtgcc ccactcgcac gtctgggacg aggagctgct
    11341 gcgggaccac gacctgccgc tctgtgccgc cggaatccac cccgacgcca ccccggacga
    11401 gctcgacctc agctcagact ggctggcctg gggcacgtac ggcgacgact actaccccgt
    11461 cgtcttcgga cggcagcggg atctcgcggg cgcgcgggtg tgcacggaac ggctacgggc
    11521 gttcatgccg ctggagtccg agcccgtgcc gcccccggcc aacgccctgg agcggggtct
    11581 tgcggacctg tggacgcgta cggcggggcc gatggccgcg gcggcgcggc gcgcgctccg
    11641 taaggcggtc gaggacatga cggacagctg gctgtgggag ctcggcaacc aggcgcagaa
    11701 ccgcgtcccg gacccggtcg actacatcga gatgcgccgg ctgaccttcg gctccgacct
    11761 caccatgagc ctgtgccggc tcgcgcacgg cgaacggctc ccgccggaga tccacggcag
    11821 ccgccccatg cgctccctgg agaacgccgc ctcggattac gcgtgcctgg tcaacgacgt
    11881 cttctcgtac cagaaggaga tcgagttcga gggcgaggtg cacaacggcg tcctcgtcgt
    11941 gcagcacttc ttcgactgcg accgcccgac cgcggtggcg gtcatcgggg atctgatgag
    12001 ctcccgtatg cgccagttcc agcacgtcgt cgcccacgaa ctgcccgtcc tgcacgacga
    12061 gttctccctg gacgcggtgg cggtcgcggc cctggacgac tacgtacggg acctggagaa
    12121 ctggctgtcg ggcatcctca cctggcacca gggctgccgc cggtacacgg aggacgacct
    12181 gcgcaggcac gccgccgcgc ccccggcggc gggcggcgga ggcggcccgt ccgcgtatgc
    12241 gctgccgacc gggctcggca cctcggcggc acgcctggcc cgtacggcgg cgagcgcgcg
    12301 cggcggcgcg ggctgacggc gcgcaggctg actgcgcggg cgcgcggcgg gcgcgcggcg
    12361 ggacgcgggg gcgcggacgg gagggcgggc gcgggtcggg ttgtcccagg gagcgcctac
    12421 cctggtgcca tgaccgcgca ggacaccttc acgcgaagct acgagatccg cacgttcggc
    12481 tgccagatga acgtccacga cagcgaacgc atggcgggtc tgctcgagga cgccggatac
    12541 gtgcgcgcgc ccgcggacgg cgacggcgcc gacgtcgtgg tgttcaacac ctgcgcggtg
    12601 cgcgagaacg cggacaaccg gctgtacggc aacctcggcc agctcgcccc gaagaaggcc
    12661 gcgcacccgg gcatgcagat cgccgtcggc ggctgcctgg cgcagaagga ccgcgacacg
    12721 atcgtgcgca aggcgccgtg ggtggacgtc gtcttcggca cgcacaacgt cggcaagctg
    12781 cccgtgctgc tcgagcgcgc ccgcgtgcag gaggaggcgc aggtcgagat cgccgagtcg
    12841 ctggaggcgt tcccctcgac gctgccgacg cggcgcgaga gcgcgtacgc cgcctgggtc
    12901 tccgtgtccg tcgggtgcaa caacacctgc accttctgca tcgtcccgca gctgcgcggc
    12961 aaggagaagg accggcggcc cggcgacatc ctggccgagg tggaggcgct ggtcgacgag
    13021 ggcgtcagcg agatcacgct gctcgggcag aacgtcaacg cgtacggcag cgacatcggc
    13081 gaccgcgagg cgttcggcaa gctgctgcgc gcgtgcggcc gcatcgaggg gctggagcgg
    13141 gtccgcttca cctcgccgca cccgcgcgac ttcacggacg acgtgatcgc cgcgatggcc
    13201 gagacgccga acgtgatgcc gcagctccac atgccgctgc agtcgggctc gtcacgggtg
    13261 ctgaaggcga tgcgccgctc gtaccggcag gagcgctacc tggagatcat cgagaaggtg
    13321 cgcgcggcca tgccggacgc ggcgatctcc accgacatca tcgtgggctt cccgggcgag
    13381 accgaggagg acttccagga gacgctgcac gtggtgcgcg aggcgcggtt cgcgcaggcc
    13441 ttcaccttcc agtacagcaa gcgccccggc acgcccgccg cggagatgga cgggcagctg
    13501 ccgaaggccg tcgtgcagga gcgctacgag cggctggtgg agctccagga ggagatctcc
    13561 tgggcggaga acaagaagca gctcggccgc accgtcgagg tcatggcggc cgagggcgag
    13621 ggccgcaagg acggcgccac ccgccgcctg tcgggccgcg caactgacaa ccggctcgtg
    13681 cacttcacgc cgggcgagga cgccgtacgc cccggcgacc tcgccaccgt cgagatcacc
    13741 tacgccgccc cgcaccacct cctcgccgag ggccccgccc gctccgtccg ccgtacgcgc
    13801 gcgggcgacg cctgggagcg ccgcaactcc gcaccgcagg agccgggttc cggttccggg
    13861 gtgctgctgg ggctgccgac cgtcggcgca ccggagccgc agcccgccgc cacgggcacg
    13921 ggaagctgcg gcagctgctg aggggcgcgc gtgccggatt cacacgccaa gtgaccatac
    13981 gattccgggc cgtcgtcgtc taagctgcgc gccatgcttg tcgccgccgc cgtgtgccct
    14041 tgtccacccc tgctggtgcc cgaggtggcc ggtgcggccg cccccgagat ggacggcgcc
    14101 cgcgccgcct gctacgacgc gatcggcgtg ctggccgccg cgcgcccgga ccggctcgtc
    14161 gtcgtcgggc ccgccgaaca gccgggccgc ggcccgcatc cgcagggcgc gcccgggtcc
    14221 ttccgcggct tcggcgcgga catcgaggtg accctgggca agggcgaccc cgcccccggc
    14281 gcgcgcgacc tgccgccgtc actcgcggtc ggcgcgtggc tcctcgaccg tacggactgg
    14341 agttccgcgc cgctggaggg gctcggcgtc ggcgagccgc tgacccgcga ccgctgcacg
    14401 gccgccggac gcgaactggc cgcgagcgca cgccgcgtgg cgctgctcgt catgggtgac
    14461 ggcagcgcgt gccgcacgct gaaggcgccg ggctacttcg acgagcgcgc cgccgcgttc
    14521 gacgcggagg ccgcccgcgc gctgggtgaa gcggacctcg acgggctgct cgccctggac
    14581 gaggagctgg cgtacgagct gaaggccgcc ggccgcgcct gctggcaggt gctcgcgggc
    14641 gcgggggagg gcgccgggct cagcgggcgg ctgctgtacg acgaggcgcc gtacggcgtg
    14701 ggctatctgg tcgccggctg gtcgtagcgc gcaagcggcg ggccggcccg tacgtccgcg
    14761 agctgtccgc ccgtacgcgc gtccgcggcc cgccgggcgc ggccgtacgg cctcttcggg
    14821 ctgagcggcc gcgcccgcgg tccacgggtc cgccggtgtc aggcggcgtc gctcccgccg
    14881 cgttcgccgc cgcgggtgtc gtctcccatg cggtccatgc tgtccttggc cttgtcggtc
    14941 ccggactgga tcttgtcgga gtgcttgccg cccgttttct cgttgagggt gtcggcaccc
    15001 ttgtccatgc cctggccggc cttgtcgctg tgctgcccga gcatgccctt gaccttgtcc
    15061 atgaagccca tggcggtcac cttccgttgt ggcgactgtg tgcgggcgct cccgccgctg
    15121 caccggtctg ccgctccgcc tacgcgagcg gcacgcagcg gcgatatccg aataaaacgc
    15181 ccatatctac tcaagaccat acccggccgg gtgagattcc gccctgtccg gagtgccctc
    15241 ttgccgtccc ggccccgccg tgctgcggcg ccgtacggcg cccgttcggg aagggcccgc
    15301 ggcgtttgcg agaattacgc atgtgacagt cccggtatcc gccttccggc ccgcccccca
    15361 ggtcatcgca gtcgtcggtc ccaccgcggc cggcaagtcc gacctggccg tcagtctcgc
    15421 ccggcaactg ggaggcgagg tggtcaacgc ggactcgatg cagctgtatc agggcatgga
    15481 catcggcacc gccaagctca ccgccgagga acgccagggt gtgccgcacc atctgctgga
    15541 catctggcac gtcacggtcg cggccagcgt cgccgagtac cagcggctgg cccgcgccga
    15601 gatcgaccgg ctgctcgccg ccggccgcgt gcccgtgctg gtcggcggct ccgggctgta
    15661 cgtgcgcggg gtcatcgacg tcatggagtt ccccggcacg gacccggccg tacgcgcccg
    15721 gctggaggcg gagctcgccg agcacggcac ccgcgccctg cacgcccgcc tcgccgcggc
    15781 cgacccggac gccgcccgcg ccatcctgcc cagcaacggg cgccgcgtcg tacgcgccct
    15841 cgaggtcatc gagatcaccg gccgcccctt caccgcgaac ctccccggac acgaggccgc
    15901 ctacgacacc ctccagatag gcgtcgacgt cgcccggccc gaactggacg agcggatcgc
    15961 cgaccgggtc gaccgcatgt ggcgtgccgg gctcgtggac gaggtgcgtg cgctggagga
    16021 ggtcgggctg cgccagggcc gtacggcctc ccgtgccctc ggctaccagc aggtactcgc
    16081 cgcgctcgcc ggggagtgca cggaggacga ggcgcgggcc gaaacggtgc gcgccaccaa
    16141 gcggttcgcc cgtcggcagg actcctggtt ccgccgggac ccgcgggtcc actggctcag
    16201 cggagctgcc tccgaccggg gggaactcac cgccagtgcc ctgacgttgc tcgaacgagc
    16261 ggtcacagcc tgatcacgtg atggcatcgg gacgtcctgg gcgtcaatag gggggtcccg
    16321 gtcgtgccat catcaaccat cgttcgagcc gagcagccgg agttgggagg gcgcgtggcg
    16381 atggaggcca gccctcgtga caacgaagag tcccgggtcg actacgtcag tgacggagac
    16441 gtcggacgcc cgggcgtcga cgacgacctt gcggcagtgg cgggcgtgga cggtcccgtc
    16501 gggccgcccg tggagccgca cgagctgcgt ccgcagcgcc gtctgcggct ctggcagctg
    16561 gcgccgatcg tggtgctcgg cgcgctgggc tcgctgatgt tcgcgttccc gctggccttc
    16621 gagccgggca gccgctccgg cgccgtcgtg tccatgctcg ggctgctgat ctgctgctgc
    16681 gcggcgggct ggggcgtgat ggccgcgcgc cgcgtcggcc acacctggcc ggggctgccg
    16741 tcgcccggtt cgggcaagcg tgcggactgg cgcgtggtgc tgctgtacgc cgtcgtcgtc
    16801 ggcacggtgg cggtgctcgc cgtgtggcgc gtcgcgcggc tcagctgagc ccacgcccac
    16861 gcccgtacgc gtacgcatcg cctccgcgct cctcgcctcc gcgctccgcc cgtacgcgcc
    16921 gcgcccgccc ggtcccgtac gatcgacggc gtgagcagcg cgcggcccgt gccgttcctc
    16981 aagggacacg gcaccgagaa cgacttcgtg atcatccccg acccggatgg cgagttcgag
    17041 ctgtccaagg aggccgtggc ccggctgtgc gaccggcgcg ccggcatcgg cggcgacggg
    17101 ctgctgcggg ccgtacgctc cgcgcggcac ccggaggcgc gcgggatggc cggcgaggcc
    17161 gagtggttca tggactaccg caacagcgac ggcagcatcg ccgagatgtg cggcaacggc
    17221 gtacgggtct tcgcccgcca cctggtacgc gccgggctgg caccggccgg cgagctggcc
    17281 gtggccaccc gcgcgggcat ccgccgcgta cggctcgccg cggacggcgg cggcgtcacg
    17341 gtcggcatgg gccgggcggc gctgcccgcc ggggacgtgc gggtgaccgt cggtgaccgt
    17401 acgtggcccg cgcggcacgt gaacgtgggc aatccgcatg ccgtggcctt cgtcgacgac
    17461 ctcgcggcgg cgggcccgct gcgcgaggcg ccgggcgtcg cgccggccgc cgcctacccg
    17521 cagggtgtga acgtcgagtt cgtggtcgac cggggcccgc ggcacgtcgc cctgcgggtg
    17581 tacgagcgcg gctccggcga gacccgttcc tgcggcaccg gcgcctgcgc cgtgatggtc
    17641 gccgccgccc gccgggacgg cgccgatccc tccgcggacg gcaacccggt gacgtacacg
    17701 gtggacgtgc cgggcggccg gctcgtcatc agcgagggca ccgacggcgg tatcgagatg
    17761 accggtccgg ccgtcatcgt cgctgaaggg atgctcgacc cggacttgct cgccgtctga
    17821 catcctgccc cggtgcggtc agttcgccac gaagagtgac gatcgtgcgc cctttccact
    17881 caggcgtata acaaacgtcg ctcgattggg tgatcccgaa caccccgggc aagaggcggt
    17941 gatcggctcg tggtgggctc tgtagcatca caccaccgga cacggggtgt tcacgagcgg
    18001 gaggtgccat gggcgcggtg cgaaaccttc ggaagctcag ccgggccgcc ctgctccggc
    18061 ccgccccccg cggcgcgctg ccggacgcca tcgagcacgt cgcgcaggcg caccgcgcgc
    18121 accaccccgg cgccgacctc gacgcgctgc ggcgcgcgta tctgctcgcc gagtcctcgc
    18181 accgcgggca gacccgcaag agcggcgagc cgtacatcac gcatccgctc gccgtgaccc
    18241 tgatccttgc ccaactgggc gcggagcaca ccacgttgac ggcctcgtta ctgcacgaca
    18301 cggtcgagga caccgacgtc acgctggacc aggtgcgcgc cgagttcggg gacgaggtgt
    18361 gccatctcgt cgacggtgtc accaagttgg agaaggtcga ctacggcgcc gcggccgagc
    18421 ccgagacgtt ccgcaagatg ctcgtcgcca ccggcagcga cgtccgcgtg atgtccatca
    18481 agctcgcgga ccgcctgcac aacatgcgta cgctcggcgt gatgcggccc gagaagcagg
    18541 cccgtatcgc caaggtcacc agcgacgtgc tcattccgct cgccgaacgg ctgggcgtcc
    18601 aggcactcaa gcgggagctg gaggacctgg tcttcgcgat cctgctgccc gaggagcacg
    18661 cgcgcaccca ggagttgatc cgcgagcaca ccgcgcgccc cgacccactc acccaggtcg
    18721 ccgcgaccgt acgggcggtg ctgcgcgagg cggagatcga cgctcaggtg ctcatccggc
    18781 cgcggcacct ggtctccctg caccggctgc ggctgaaacg cggcgagctc ggcccctgcg
    18841 acttcgggcg gctgatgatc ctcgtggccg aggacgccga ctgctacgcg gcgctcggcg
    18901 aactgcacac ctgcttcgtg cccgtgatgt ccgagttcaa ggacttcatc gcggtgccca
    18961 agttcaacct ctaccagtcg ctgcacaccg ccttcgccga caaggacggc cgcgtcgccg
    19021 aagtcctcgt ccgtacgcgg cagatgcacc aggtcgccga ggccggtgtg atcgcgctcg
    19081 gcgatcccca cagcgcgccc gcggaagccg aagcggaagc gggcggcgac ggcgaacggg
    19141 ccgacccgac ccggcccggc tggctctccc ggctgctgga gtggcagagc cacaccacgg
    19201 acccggacac gttctggagc gagctgcgcg acgagctggc cgaggaccgc gagatcaccg
    19261 tgtactgcgc cgagcccggc accggcggca gcagcggcgc gctgccgctc ccggccggcg
    19321 ccagctgcgt cgacgccgcg tacgcgctgc acggcgaggc cgcgcaccgc tgcatcggcg
    19381 cccgcgtcaa cgggcggctc accgcgctca gcacggtgct gcgcgacgcc gacacggtgc
    19441 agctgttcct ggctcccacg accggcaccg ccgcgtacgc gcccgcgccg gagtggctcg
    19501 accacgcgcg gacgcccgcc gcccgcatcg ccatccggaa gtggctcgcg gcgcacccgc
    19561 ccgtaccggc cgccgacacc gtgacggccc ccgcggagca cggcacggac gcccggcccg
    19621 cgccgcggcg cgacgcgcga ccggaacccg tcgcggaatc ccgtacgcac gcccccgcga
    19681 catcaccgtc cagcgcaccg gcttcaccga agcatgccgt cctcgcgctc gcccgccgcc
    19741 gcgtcaacgt tctcttcgcc atgatccgtg accgacagtg ctaccacgct ccgccttccg
    19801 tcacgaccgc cgcttgacaa caacatgagg aggtgtcacg tacacccccg ggagggcgct
    19861 caggcccatg ggccgcggct tgggggctcc gtagcgtcgg gcgcatgagt ggagacagct
    19921 acggcggacg agtgactcgt cgcatcgctt tgcggaatgc cggcatcgtc gcgggcgggg
    19981 ccgcgctcgc cgcgggtacg ggcgccggta cgggtgcggc ctcggcggcc gtgcgcggcg
    20041 cgccccacgg tggcgggcgc ccacggcacg ggacggtgcg cacgtacgtc ctcgtgcacg
    20101 gcacccacag cgccggtgcc tactggaccc ccatcgcccg cgaactcacc ctgcgcggac
    20161 accgcgtcgt ggccgtggac cagccgctgc acggcgccga ggcgttcgtg ccggaggcgt
    20221 accagacgca ggacctgcgg gccctcgcca ccgagccgtc gccggtggcc cggctcggcc
    20281 tggacgacta cgcgcggcgg gtcgagcagg ccgtacggcg cgccgccgag cacgggccac
    20341 tggtgctcgt cgcgcacagc atgggcggca tctccgtcac ccgtacgggg aacgccgtgc
    20401 ccgaactcat cgaccacatc tgctacatgg cgtcgttctg cccctcccgc agcatgccga
    20461 cgctcaacga ctgcatgtcc gcgccggaga gcgcctccgc cgtcagcacc gacgagcagg
    20521 tcgtcggcga catggaacgg ctgggcgtgg cgcgcttcaa ctggcgtacg ggcaggcgca
    20581 aggacctcga cgtcttcaag gagatgatct gcgcggacca tccggacgac gcgttccggc
    20641 gggtgatcgc cgggatgcag acggacgaga cgctgcgcgc gtacggggaa cgggcggtcg
    20701 gcgagcggga cacgtggggg cgggtgccgc ggacgtatct gcggttcggg cgcgaccggc
    20761 tggtcacgcc ggagctccag gaccggatga tcaacgaggc ggaccggctg acgcccggga
    20821 accagttcac cgtgcacgac ttcacgcggg cgccgcacat cggcccgctc gatcccgcac
    20881 cggtcgtgga cgcgctggag ggggtggcgg tacggcggcg gtgaccgtac ggggggtgac
    20941 cgtacggggg ggggtgaccg tacgggcgag ggcgtccggg gcaggcggca acaggcgtac
    21001 ggggcgcgct cgttcagcgg ccgacgagga cgccggtgac cgcctcggcg gccgcgacga
    21061 cggccgcctc caccgtgtcg atccccgtcg cctgggacgg ctgaccgtcg cagagcacgg
    21121 cgaggagcag ctcgtggccg tcgtgccgca ccacgccgac gctgttgacg acccacaggc
    21181 cggaggccgt acggggcagc cagccgttct tcagcgcggt gcccgtcccg gggtcggcgg
    21241 cggccgacac gccccagtcc tgcccggacc gtacccgcga catgagcgcg cgcacgtacg
    21301 cgcgggactc gggcgtcagc ggcgagtcgg cggcggtgac cgccgtgagc agccgcaact
    21361 ggtcggcggc ggtggtcgtg gtcaggcccc agtggtcgtc cgcgccgggc acggtcccgg
    21421 tgaggccgaa cgtccggttc gcctcggcga ggccgtcggc accgccgatg gcgcgccaga
    21481 ggcggtcggc ggcgtggttg tcgctgacct ggatcatctg gcgggcgtcg gtccgttgct
    21541 cggcagtgag cggccgaccc tccttctggg cgcggagcag gagcgcggcg aggatgccga
    21601 ccttggcgac gctcgcggtg acgaacgcgt gctcgtcggg cggcgcgtag acggcgctgc
    21661 tgccggacgc ggggtcaccg atcgccagcg agacgtttcc ctcggccgta cgggccaggc
    21721 cccggagggc ggcggcgagt acggcgtcgg gggcgggggc agccgtgccc gcgaaccacg
    21781 ccacgccggt ccctcccctc cgcgtacggc aggccgtcgt gcggcctgtc ctcgtacggc
    21841 cgaccctcgt acgggctacc cgcaagcggg cccaccgtat gcggccgttc cgcacaaacg
    21901 gcctgcgcgg gcggcccgtt cactcccgcg ccgtgaagcg ccgtaccgcc tggtcgagat
    21961 gctcgcgcat caccgcgcgc gcgtgcccgg cgtcgttgcc ggagacggcg tcgagcaggg
    22021 tgcggtgttc gcgcgcgagg tcgtcggggc gcgggtagga cggctgcagc tgggcgaggc
    22081 agagctgcat ctcctcctgc aacggcggat acagccggct caggcgcggg ctgcccaccg
    22141 cgtccaccag agcgatgtgg aacgcggtgt gcgcctgcac gcggtcggcc caactcgcct
    22201 ccgcaggcag cgcctccagc tcccccagcc ggcggcgcac cggggtcacg tcgatccgcc
    22261 gctccacgat cgcggtgacg acctcgtact cgagcggggc acggacgaag tgcagg
//
