LOCUS       NZ_CP031320            22766 bp    DNA     linear   CON 04-MAY-2024
DEFINITION  Streptomyces armeniacus strain ATCC 15676 chromosome.
ACCESSION   NZ_CP031320
VERSION     NZ_CP031320.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces armeniacus
  ORGANISM  Streptomyces armeniacus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Draft genome of the type strain Streptomyces armeniacus ATCC 15676
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8083249)
  AUTHORS   Labana,P., Gosse,J.T. and Boddy,C.N.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2018) Department Of Chemistry and Biomolecular
            Sciences, University Of Ottawa, D'Iorio Hall, 10 Marie Curie,
            Ottawa, Ontario K1N 6N5, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: JUL-2018
            Assembly Method                   :: SPAdes v. JULY-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003355155.1-RS_2024_05_04
            Annotation Date                   :: 05/04/2024 02:13:56
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,031
            CDSs (total)                      :: 6,963
            Genes (coding)                    :: 6,742
            CDSs (with protein)               :: 6,742
            Genes (RNA)                       :: 68
            rRNAs                             :: 6, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 57
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 221
            CDSs (without protein)            :: 221
            Pseudo Genes (ambiguous residues) :: 0 of 221
            Pseudo Genes (frameshifted)       :: 36 of 221
            Pseudo Genes (incomplete)         :: 204 of 221
            Pseudo Genes (internal stop)      :: 5 of 221
            Pseudo Genes (multiple problems)  :: 22 of 221
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 18:36:10
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2310465
            Orig. end                         :: 2333231
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031320.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22766
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="10"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22766
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22766
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12766](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12766
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            255..1466
                     /locus_tag="DVA86_RS10080"
                     /old_locus_tag="DVA86_10150"
     CDS             255..1466
                     /EC_number="3.1.21.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /locus_tag="DVA86_RS10080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10150"
                     /product="restriction endonuclease subunit S"
                     /protein_id="WP_208877527.1"
                     /transl_table=11
                     /translation="MSGDDGVRWVPVGELGEVRMGKQLSPSSLNSGRPHPYLRVANVLH
                     GRIDFSDVKTMGFTSSELATYSLKPGDILLNEGQSLELVGRSAVYDGPEGEYCFQNTLV
                     RFRVGPDVLPGYAQQIFTHWLANSVFAGIAKKTTSIAHLGADRFARLKFPLRPIAEQRR
                     IVEALGSVADTERAVESTIAKLRSMREATLLSAIPLDGHSTKPGWTNVPLKEVVPSVQY
                     GISEALDRDERGLPTLRMNNLRNGKPDVTELRYCPTPVREDLLLKGGDVLFNRTNSIDH
                     VGKAGIWRGELPRATFASYLVRLHPDTKRLSPEYLVEWLRHPLTVQRVRAIATVAVQQV
                     NVNPSRLRELTIALPIAPDRQHQIVSTLASMDDRINRELEALAKTRKLKRALADDLLSG
                     KIRV"
     gene            complement(1475..1711)
                     /locus_tag="DVA86_RS10085"
                     /old_locus_tag="DVA86_10155"
     CDS             complement(1475..1711)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143278.1"
                     /locus_tag="DVA86_RS10085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10155"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_208877529.1"
                     /transl_table=11
                     /translation="MSEQLTWFKSSYSNDEGGACVEIALAWHKSSYSNREGGNCVEVAN
                     RPGAVHVRDSKDAAGPELAFPAAAWSAFVAHAG"
     gene            complement(1708..2493)
                     /locus_tag="DVA86_RS10090"
                     /old_locus_tag="DVA86_10160"
     CDS             complement(1708..2493)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563966.1"
                     /locus_tag="DVA86_RS10090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10160"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_208877530.1"
                     /transl_table=11
                     /translation="MAWQYCGSQMKLWRERAGVRREDLASEAGYSYEAIKSMERGVRKP
                     QLAALRVADELCGAKGLLVAATEFLKPEPFPSYSQDFMQAEAEAVVVCWYETQFIPGLL
                     QTEGYVRALLNAHCPPLDDETVDERIVARLARQPLLDRQSKSFNFVVEEAALRRRVGDA
                     DVRRAQLEHLMVAGRARHVNIQVMPAELGSHPGLKGPFILLESSEREHLGYEEGQTTGV
                     LYSDSEKLSILRQRHEMILRLALSPEESARFIGELMEAL"
     misc_feature    complement(2509..2524)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 20.14"
                     /tool="antismash"
     misc_feature    complement(2606..2621)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.55"
                     /tool="antismash"
     gene            2629..2847
                     /locus_tag="DVA86_RS10095"
                     /old_locus_tag="DVA86_10165"
     CDS             2629..2847
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019354867.1"
                     /locus_tag="DVA86_RS10095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10165"
                     /product="hypothetical protein"
                     /protein_id="WP_208877531.1"
                     /transl_table=11
                     /translation="MNSEIPPAGSYAVDTRNGRVGEVMGKEGPYAQLRPPLGGREWDVP
                     PENLRPARTGEELSARVRGLNRNSQLP"
     gene            3042..4034
                     /locus_tag="DVA86_RS10100"
                     /old_locus_tag="DVA86_10170"
     CDS             3042..4034
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVA86_RS10100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DVA86_10170"
                     /product="hypothetical protein"
                     /protein_id="WP_208877532.1"
                     /transl_table=11
                     /translation="MFRHVTAPARYFSQLPNEIIRHPRLTSDAVRLLAWQLSLPGGANE
                     PLSRTAARAGIGKTAFQRAKRQLLDEGYLHEWRRQGERGRWRTVQLISNVVVSAADARA
                     LWDGGIVTAPKPTQKATPAPVPPAVPAAQPPAAALPAAGPPTGQAVGRQPRTNTTEYTP
                     HPPDDASRLAEAEALLRSLGSHEPRLVMPARKARAWAPLAAEWLASCLSPELIRQTLTH
                     GLDKARSPLGALRWRLEHALPEQSYGPPPPQPRAPEPRIARMRECTGAHTQPRLFAPSS
                     ADDELCPGCRDTPTAAAPPGPGLRAFRTARAGARTDTRTSAKTAVSAMA"
     gene            4151..7822
                     /locus_tag="DVA86_RS10105"
                     /old_locus_tag="DVA86_10175"
     CDS             4151..7822
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_process="GO:0006304 - DNA modification [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037510.4"
                     /locus_tag="DVA86_RS10105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10175"
                     /product="type I restriction endonuclease"
                     /protein_id="WP_208877533.1"
                     /transl_table=11
                     /translation="MAPQTTEQDEAERPFAAQLESMRWTHVRGSELTEEDREPGHPLLT
                     GRLAEAVRRINPATPRHAADGTPTPASSWLDESAVGEVVGRLRRLVEHTDGPTLEDANR
                     EATRLLLGGTTMRAPSGRDDPVHYIDWEPGSSRNDFLAVSQFQVRTPGGRTATLDLVLF
                     VNGIPLAVVECKSPDLADPLGDAIRDLRAYAGRPLDTDERPGREHPCGVPAVFATAQLL
                     VAADGTQAALGTISADEAHYAAWRSVTPDYEDDKALHREMRRAQQESLPGERHFLAAGQ
                     DINGQHRLIAITLNQPNLLNIVRHYICELPVKNDAGEVVKRVKAVCRHQQYRAVEKIVH
                     GLRTRPSRLAPGAVEDDRGGVVWHTQGSGKSLTMAFLVRRLHMNRDPALNAFTVLVITD
                     RKQLQDQLSEALQRSESPLQTAESQADVEGMLEYAGRPGGRMVVFAMIQKYLGRVPGLV
                     LDETARDERSLADDFEQARQRIDAGEDPADVVDPVPAENPARRREFRWCSDSDKVLVLI
                     DEAHRSHASVLHACLRDAVPNAARIGFTGTPILQGRKKLSSEIFGRTIDVYRMDEAEAD
                     GVVVPVRYEGRTGPAQVTEGEDLNTRFADLLAPLTAKQKEALRGRWNRPTGRDVAESVP
                     MIRAKAVDMLIHYVKGPLRRGFKAQVAAVSREAAVLYRHALRDARAELMARVRSFDPDR
                     LRGVDPRDYRAYPKDPFNDDLLLLKAWQFQRVLRRIDFVPVISAGVEQKSGRWREWTDP
                     DCQAEHIARFLQPLPTPPPENPWATEHPEEERKGDPPPLGGTNPWSKSGLPPALAEEPP
                     VAFLIVKSMLLTGFDAPVEQALYLDRPIRDAELLQAVARVNRPAPRKELGLVVDYYGVL
                     KDLTVTLATYRDDPSPEVREGGMRDMATEVPGLEAAAAEVERFLGDREITGLHSRAGMV
                     NAMLMLADEDDRAEFDRLLSEFMRSLDRVLPHEAALGHVADAQWWTLLQKRVRRLYRDA
                     PDGDFSLRAYGREVREMIADHLSLPQITQEIVPVSINDPEFDAAVERLANVRLAAAEQQ
                     HGLRYHLEQHERRERPQLYEELSKELDRVLREFDGRWEEMKRELGALIVRARQQDEANP
                     ALAGLTPAERLMHAQLADRLAREGDGLALPDEQLRDLGVQVCAAVTARVTLASFRSQES
                     HLTSLETEIFQAVRGGLRAAGIRTGTEVHRNIARSLAGHVQEHLPQYQRASGTTGGW"
     gene            7937..8632
                     /locus_tag="DVA86_RS10110"
                     /old_locus_tag="DVA86_10180"
     CDS             7937..8632
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013980.4"
                     /locus_tag="DVA86_RS10110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10180"
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="WP_281279273.1"
                     /transl_table=11
                     /translation="MSAQRRRLGLTVERDGSLTLRVPEGCELHRAEDFVRASHRWIEDK
                     LRLRQRHLPLNPARGLTHGEVFRYLGRDYRLALVDTEGAPVRLRHGELLLDRGLASSRR
                     SAVRALTDWYSRTGLRWAQGHTQPWAGRMEVPEPTLEVRDLGRRWGTYRSGDGEGTGAG
                     RVSLHWAVFQLPGALVDYVIAHELAHTRIAGHGPDYWRLLGRAIPECRSRKAELDEMGR
                     RVWLGDVSR"
     gene            complement(8715..9305)
                     /locus_tag="DVA86_RS10115"
                     /old_locus_tag="DVA86_10185"
     CDS             complement(8715..9305)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.4"
                     /locus_tag="DVA86_RS10115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10185"
                     /product="CAP domain-containing protein"
                     /protein_id="WP_208877534.1"
                     /transl_table=11
                     /translation="MVEWRGTSVCDGAARAVATVLCGLALAAGHGGGAESGAGGGAGGG
                     ADGARGRAAAASAAFAAPVAYAGPAVETEVVALVNEHRTEAGCPAVRTDPDLREAAEEQ
                     SGHMDRTGELTHVGAGGTQPLARAEAAGYDTERLAENLAHGPSGAAAVVDAWLDSPAHR
                     ANLLDCAYRDMGVALTGAPADPWWAQVLGTERD"
     gene            9856..9984
                     /locus_tag="DVA86_RS10120"
     CDS             9856..9984
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF033521.1"
                     /locus_tag="DVA86_RS10120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lasso RiPP family leader peptide-containing
                     protein"
                     /protein_id="WP_208877535.1"
                     /transl_table=11
                     /translation="MEKVTTEVYEPPALVGIGEFSEVTLGPNNDLLVDWDGYFLWY"
     CDS_motif       9856..9930
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MEKVTTEVYEPPALVGIGEFSEVTL"
                     /locus_tag="DVA86_RS10120_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       9931..9984
                     /prepeptide="core"
                     /locus_tag="DVA86_RS10120_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="4.10"
                     /molecular_weight="2069.2"
                     /monoisotopic_mass="2067.9"
                     /core_sequence="GPNNDLLVDWDGYFLWY"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MEKVTTEVYEPPALVGIGEFSEVTL"
                     /leader_location="[9855:9930](+)"
     gene            10001..11899
                     /locus_tag="DVA86_RS10125"
                     /old_locus_tag="DVA86_10195"
     CDS             10001..11899
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012936.4"
                     /locus_tag="DVA86_RS10125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10195"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_208877536.1"
                     /sec_met_domain="Asn_synthase (E-value: 7.7e-20, bitscore:
                     70.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEEWFAVLPDSDTGLAAARALRPLASDVIEHASGRPWLLGRWPE
                     REVTVATAGTVRLAVAGCSPATVGSLRERLRGARSVHDMDRTVARLPGCFHLLASVDGR
                     VRAQGTLASVRRVFHARVGDAVIAADSALVLARLTGADWDPSWLALRLANMTAPFPLHE
                     TTPWRGVRAVPGDHWLELAQDGTAAERRRWTAPEPALPLTEGAPAVRDALAAAVQTRTT
                     HGGTVSTDLSGGMDSTSLAFLAGRGPAKLVTFRMAERDAGNDDAYFADRAAALLPRAHH
                     RVHRPDRTAAMFAGLGPDTAAADPEAPFAWMRTRARLAHAVRAMAAEGSRVHLAGHGGD
                     ELFRPDTTYLHDLFRAHPRTALRYLRAHRTLGRWSAPALARALADSRTPGHELADQALR
                     LRAPRPGLRHVSFAWSPLLRLPDWVTDDAAETAGELLRAIATDPADPVEPLADGRAQHG
                     VVLMARCTGASVRQANRVNASPASSGPGGSPGGPPFAVPYLDDHVLSAALAVRLEDRNS
                     PWRFKPLLAAAMRGIVPEELLHRTTKGAFGADYYAGLRRHRAELLALFDGSELARHGLI
                     DDATLRRALLRPHKDNTALSGLDATLACEAWLRSLNARATAGPHTGSGTVPDPVPH"
     misc_feature    11192..11194
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11922..12344
                     /locus_tag="DVA86_RS36080"
                     /old_locus_tag="DVA86_10200"
     CDS             11922..12344
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lasso_Fused_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF033530.1"
                     /locus_tag="DVA86_RS36080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10200"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_208877537.1"
                     /sec_met_domain="Lasso_Fused_RRE (E-value: 2.7e-06,
                     bitscore: 26.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-19,
                     bitscore: 69.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3e-12, bitscore: 45.3,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTSSTPSSSSASPDPLTPLVLRPHITATPTADGMVLLDQRTGA
                     YWQMNTTATLVLHALLDGADAEQAAALLAARHPAAAERADSDVAALIRQLHDAGLAQPR
                     DGARERGPGRGSGSGPNRNRNRDRTQNRKPDQESRT"
     aSDomain        11976..12230
                     /aSDomain="Lasso_Fused_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing fused peptidase in a lasso
                     peptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DVA86_RS36080_Lasso_Fused_RRE.1"
                     /evalue="1.10E-08"
                     /identifier="RREFam003.1"
                     /label="DVA86_RS36080"
                     /locus_tag="DVA86_RS36080"
                     /protein_end="103"
                     /protein_start="18"
                     /score="26.0"
                     /tool="antismash"
                     /translation="TPLVLRPHITATPTADGMVLLDQRTGAYWQMNTTATLVLHALLDG
                     ADAEQAAALLAARHPAAAERADSDVAALIRQLHDAGLAQP"
     aSDomain        11988..12227
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DVA86_RS36080_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.10E-22"
                     /identifier="RREFam002.1"
                     /label="DVA86_RS36080"
                     /locus_tag="DVA86_RS36080"
                     /protein_end="102"
                     /protein_start="22"
                     /score="69.0"
                     /tool="antismash"
                     /translation="LRPHITATPTADGMVLLDQRTGAYWQMNTTATLVLHALLDGADAE
                     QAAALLAARHPAAAERADSDVAALIRQLHDAGLAQ"
     gene            12341..12766
                     /locus_tag="DVA86_RS10135"
                     /old_locus_tag="DVA86_10205"
     CDS             12341..12766
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016640867.1"
                     /locus_tag="DVA86_RS10135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10205"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_208877539.1"
                     /sec_met_domain="PF13471 (E-value: 3.3e-30, bitscore:
                     103.2, seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYDVVLPTHDRLPFRRRPSALLAVAAARLLATLPPYRIGQVLRT
                     LRRRAAPATAGQASNARLAVVTVSRRCTSPQGCLQRSLATALLCRLRGVWPTWCTGVRT
                     QPFSAHAWVAVDGTPIDEPQAADYYTPVLAVPPRRRP"
     gene            12907..13854
                     /locus_tag="DVA86_RS10140"
                     /old_locus_tag="DVA86_10210"
     CDS             12907..13854
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018845680.1"
                     /locus_tag="DVA86_RS10140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10210"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_245997576.1"
                     /transl_table=11
                     /translation="MHARALAKSYPGGTEAVRGVDLAVRPGETFAFLGPNGAGKSTTIS
                     LLCALARPTAGEAHVCGADVRTEPQRVRRTVGLLFQHSALDSNLTARQNLYVHARLYGL
                     SRAAAGARGAELLALAGLDDRQRAPVRTLSGGMRRRLEIARALLHDPRVLFLDEPTVGL
                     DPHARAQIWDHLHALRAERRTTLFLTTHYLEEAEHCDRIAIIDAGRVVAEGPPRELKAE
                     IADDRLRLRTSDDAATAGILRDTFGLSPAVAGDAAVPDEADAGVTVRVGEGATWIPQLC
                     VALAARDIAVHAVSTTPPTLDDVFFHHTGRSIRA"
     gene            complement(13963..14817)
                     /locus_tag="DVA86_RS10145"
                     /old_locus_tag="DVA86_10215"
     CDS             complement(13963..14817)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014180901.1"
                     /locus_tag="DVA86_RS10145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10215"
                     /product="ABC transporter permease"
                     /protein_id="WP_245996469.1"
                     /transl_table=11
                     /translation="MNAGTAVAVRAGLQRGRIEFRQYATSGQDIWSALFTPVVSLIVMY
                     VLRDSTVPGTDFSLGTQSVPGILGLNVVLTGLVGLAMALAMDREDGTVLRAKATPNGVP
                     GYLTGKVVSRAAVTVVSLFVALVPAAFLFDGMELGGAASWLTLAWVLALGLAATLPLGA
                     MAGALAGSVQSLGFVWLLMMGLVGVSGVFYPVTALPGWLQLVAQVFPVYWLGLGLRSAL
                     LPDALAAAEAGDSWRHLETAGVLGVWAVVGLLTAPAVLRRMARRESGAAVAAGREKALQ
                     RQV"
     gene            complement(14814..15812)
                     /locus_tag="DVA86_RS10150"
                     /old_locus_tag="DVA86_10220"
     CDS             complement(14814..15812)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006348770.1"
                     /locus_tag="DVA86_RS10150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10220"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_222623308.1"
                     /transl_table=11
                     /translation="MNVSDRNDGNRPVVEVRGLRMRYGTTDALDGVDLRLDRGEVLALL
                     GPNGAGKTTTIEILEGFRHRSAGDVRVLGSDPEHGDEAWRARLGVVLQSWRDHGKWRVR
                     ELLDHLGRFYAPYGTPERPRPYDTDELIALVGLSGRAGSTVGTLSGGQRRRLDVAVGLV
                     GRPELLFLDEPTVGFDPQGRQEFHELVHRLAAAEDTTILLTTHDLDEAEKLSDRIVILA
                     GGRVVAEGSPAELARRVAGADEVRFSRDGESYVRSVPDGTEYVRGLFARHGAGIGELEV
                     RRARLEDVYLALVRDFESGQRTAAPAELTATSQAAAVADAAAVADATEVAP"
     gene            15915..16661
                     /locus_tag="DVA86_RS10155"
                     /old_locus_tag="DVA86_10225"
     CDS             15915..16661
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058143.1"
                     /locus_tag="DVA86_RS10155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10225"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_208877541.1"
                     /transl_table=11
                     /translation="MSCQGAELRPVDLAREAGVSTQLVRNYEDAGILPPARRTPSGYRR
                     LEDRHRRALLTYRALARGYGTAAARSIMRAVHDGDLPRALTHVNAAHAELHEQQRALRA
                     TGEALEAVAEQDVEQGVEQGVESAEPAQSPTGLRIGEVAAHLGVRTSALRVWESAGLLT
                     PQRTPGTSYRLYGPADVRDARMIHMLRQSHYPLPQIGPVLDDLRQAGSGDALRAALARR
                     QESLTARATAMLEGSGHLHQYVTAGA"
     gene            16836..18194
                     /locus_tag="DVA86_RS10160"
                     /old_locus_tag="DVA86_10230"
     CDS             16836..18194
                     /EC_number="4.1.1.15"
                     /GO_function="GO:0004351 - glutamate decarboxylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006540 - glutamate decarboxylation to
                     succinate [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180: Decarboxylase, pyridoxal-dependent"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006139980.1"
                     /locus_tag="DVA86_RS10160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10230"
                     /product="glutamate decarboxylase"
                     /protein_id="WP_208884569.1"
                     /transl_table=11
                     /translation="MFASEPPEVPREALPDGEMDPELAYQIVHDELMLDGNARLNLATF
                     VTTWMEPQADRLMAECFDKNVIDKDEYPRTAALEQRCVRMLAELWHAPEPAEAPGCSTT
                     GSSEACMLAGLALKRRWQQARTRAGVHVRPPAGRPNLVMGANVQICWDKFAAYWDVEPR
                     LVPMEGDRLHLTAEQAVAHCDENTIGVVAVLGSTFDGSYEPVADICAALDTLQRETGLD
                     IPVHVDGASGAMIAPFCDPHLDWDFRLPRVASVNTSGHKYGLVYPGVGWIVWRDTAALP
                     DDLVFRVNYLGGDMPTFALNFSRPGAQVAAQYYTFLRLGFDGYRRVQDYCRDVATTLAS
                     RIGHLGPFRLLTHGDELPVFACALRPEIAGYSVFDVSAHLRQRGWLVPAYTFPEHRTDL
                     AALRFVVRNGLTHDLADLLLDDLRWALTELERQPAPLRGPESASFAHGNRPRA"
     gene            18628..19395
                     /locus_tag="DVA86_RS10165"
                     /old_locus_tag="DVA86_10235"
     CDS             18628..19395
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018557512.1"
                     /locus_tag="DVA86_RS10165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10235"
                     /product="PIG-L deacetylase family protein"
                     /protein_id="WP_208877543.1"
                     /sec_met_domain="PIG-L (E-value: 8e-24, bitscore: 83.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSQQDAVLGEQQRQLEPMPEDWGRALAVVAHPDDLEYGAAAAIAE
                     WTTAGREIGYLLVTRGEAGIDGLEPGESARVREAEQLASAGVVGVGDVKFLDHKDGVIE
                     EGVALRRDIAGAVRAFRPELVITLNHHDTFGGVAWNTPDHRAVGRATLDAVGDAGNRWI
                     FTEQLELEGVEPWGGVRWVAVAASPEPTHAVAVGDESVERAVASLAEHRAYLTALSDQE
                     PAAYARSFLVPAMEQVGERFGGKRGVSFQLYPR"
     gene            complement(19383..20822)
                     /locus_tag="DVA86_RS10170"
                     /old_locus_tag="DVA86_10240"
     CDS             complement(19383..20822)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131878.1"
                     /locus_tag="DVA86_RS10170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10240"
                     /product="MFS transporter"
                     /protein_id="WP_245997577.1"
                     /transl_table=11
                     /translation="MAALRRRVHAVLVVSQILGGLGVATGIALAAVLAEDISGSEGLAG
                     LASTSSVVGTAVLSLPLAALMAAKGRRPGLALAYLIAAVGGATVVVGAMLENFPVLLAG
                     MAAFGAGSSANLQARFAAADLAEPDRRARAISTVVWATTIGAVLGPNIAAPAGRSVSAL
                     GLGIPATAGPFLWGTGIFLIAGALVQLLLRPDPLLTARALAAREAEESAGTGKPPAEDG
                     RSLRAGMAAVAASPRARLALVTIAGAHTVMVSIMVMTPVALSHHGADIDLIGLVISGHI
                     AGMYALSPVMGWLADRLGRLSVIGLAIGLLVCAAALAGTAGADHSRSAAGLALLGLGWS
                     AALVAGSALLTDSVPQPARAAVQGLSDLTMNAAAGAGGALAGVIVSQAGYGWLTAVSAA
                     LLLPVAALAFAGTLRRAAARTREGARDRTRGNGTDRTREGGPDRTREGGPDRTGSEAGP
                     AADAAALAPPAAESPPPSQRG"
     misc_feature    complement(20967..20976)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     gene            21401..22084
                     /locus_tag="DVA86_RS10175"
                     /old_locus_tag="DVA86_10245"
     CDS             21401..22084
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609328.1"
                     /locus_tag="DVA86_RS10175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVA86_10245"
                     /product="M23 family metallopeptidase"
                     /protein_id="WP_208877544.1"
                     /transl_table=11
                     /translation="MPKKVSLTTLMNHPRGQVALLASGLCASLALGAGVAAAAEQPAAP
                     APKDAFAASAAGDLAKATKQQSDAQYKAAEAGAKKAADDKKAAAKKAASWVKPVSKPYT
                     LTASFGNSGDRWSAKHSGQDFAVPTGTPVKSVHKGTVVEAGNGGAYGNNVVIEHPNGKY
                     SQYAHLSKINVQVGQDVNTGTRIANSGNSGNTSGPHLHFEIRTTAAYGSGFDPMPFLHK
                     HGVKV"
ORIGIN
        1 gccacaaccg ccgaagccgg gcctcacctt ggcccgcgag gccttgacct cggaggacga
       61 gcagaacatc gtcctacggc tgctgcacga tgatctggcg gcgaagctgg agagtcatgt
      121 ggtccgcaaa cggcgcgagt tgatcgagac ctaccgcacc tgggaggaca agtacgcggt
      181 gtccctgcgc gcgatcgagg cccgaagggc cgaggcggca acgcgcatgg agggcttcct
      241 ggaggagctg ggttatgtcg ggtgacgacg gagtccgctg ggtgccggta ggcgaactcg
      301 gcgaggtccg catggggaag caactttcgc cgagcagcct caattcagga cgacctcatc
      361 cgtatctgcg agtggcaaac gtcctgcacg gacgtattga tttctcagac gtcaagacca
      421 tggggttcac ctcgtccgaa ctcgccacgt acagcttgaa gccgggcgac atcctactta
      481 acgaaggcca gagccttgag ctggtgggtc ggagcgctgt ctacgacggc cctgaagggg
      541 aatactgctt ccagaatacg ctcgttcgct tccgggttgg cccggatgtc ctaccgggtt
      601 acgcccagca gattttcacc cactggctag cgaatagcgt gttcgccgga atcgccaaga
      661 agacgacgag cattgctcat cttggcgcgg atcgatttgc tcggctcaag tttccgctca
      721 ggccgattgc ggaacagcgt cgcatcgtag aagcgctcgg ctccgttgcc gacacggaac
      781 gggccgtcga gtcgacgatc gccaagcttc gctcgatgcg ggaagcaaca ctcctgtcag
      841 ctatcccact agacggtcac agcacaaagc ccggctggac gaatgtgccc ctcaaagaag
      901 tcgtgccgtc ggttcagtac ggtatctccg aagcgctcga tcgcgatgag cgaggtctac
      961 cgacactacg gatgaacaat ctccgcaacg gcaagccgga cgtcaccgaa cttcgatact
     1021 gccctacgcc cgtgcgcgag gacttgctgc tcaagggcgg ggacgttctg ttcaatcgaa
     1081 caaacagcat cgaccacgta ggcaaggccg gaatctggcg gggagaactt ccaagagcta
     1141 cgttcgcctc atacttggtt cgcctgcatc ctgacacaaa gcggctctcg ccagagtacc
     1201 tggtcgagtg gctgcggcac ccgctaaccg tgcagcgagt ccgagccatc gccaccgtgg
     1261 ctgtgcagca ggtgaatgtg aacccctcac ggctccggga actaacgatc gccctgccta
     1321 tcgcccctga tcgtcaacac cagatcgtct caacgctcgc ctcaatggat gaccgcatca
     1381 accgcgaact cgaagcgctg gccaaaacac ggaagttgaa gcgggcgcta gccgatgacc
     1441 tattgagcgg gaagattcgg gtgtgacgga tcagtcaacc cgcatgggcc acgaaggctg
     1501 accaagcggc agcggggaag gcgagttcgg gtccagcggc gtccttggaa tcgcggacgt
     1561 gtacggcgcc agggcggttc gcgacctcaa cgcagttgcc gccctccctg ttgctgtagc
     1621 tggacttgtg ccacgcaaga gcaatttcca cacaagcacc accctcgtcg ttgctgtagc
     1681 tcgacttgaa ccatgtcagc tgctcactca tagggcctcc atcaactctc cgatgaaccg
     1741 cgcagactcc tctgggctga gggctagccg caggatcatt tcatgccgct gacggaggat
     1801 gctgagcttt tcggagtcgg agtacaggac acctgtggtc tggccttcct cgtagccaag
     1861 atgctcgcgc tcggaggact ccagcagaat gaacggccct ttgaggcccg ggtgagaacc
     1921 cagctctgct ggcatcactt gaatgttcac gtgtctggcc cgtccagcga ccatgagatg
     1981 ctccaactgg gccctgcgta cgtcagcatc gccaaccctc cggcggaggg ccgcctcctc
     2041 aaccacaaag ttgaacgact tggactgtcg gtcgaggagc ggctgtcgcg ctaggcgagc
     2101 cacgattcgt tcatcgactg tctcatcatc gagcggtggg caatgtgcgt tgaggagtgc
     2161 cctcacatat ccctctgtct gaagaagacc ggggatgaac tgcgtctcgt accagcacac
     2221 aacgaccgct tcggcctccg cctgcatgaa gtcctgcgag taggacggga acggttccgg
     2281 cttcaggaac tccgtcgccg cgaccagcaa ccccttcgcc ccgcacagct cgtccgccac
     2341 ccgcagggcg gccaactgcg gcttccgcac gccgcgttcc atcgacttga tggcctcgta
     2401 gctgtagccc gcctcgctgg ccagatcctc ccgccggacc ccggcgcgct cgcgccagag
     2461 cttcatctgg ctgccgcagt actgccaggc catggggcgc tcggagcagt ttccattggt
     2521 caacgcacac tcaccgccgc gtcttgccgt ggtcgcaccg gatacacgca cgctctgtat
     2581 ccatgtcgtt actcgtcagc ctacgtgtgc gccagcagcg tttgagccat gaacagcgag
     2641 attcccccgg cgggttcgta cgccgtggac acccgtaacg gccgtgtcgg cgaggtcatg
     2701 ggcaaggagg gcccgtacgc gcagttgcgt ccgccgctcg gcggtcggga gtgggacgtt
     2761 ccgccggaga acctgcgccc ggcgcgcacc ggcgaggagc tgagcgcccg cgtgcgcggg
     2821 ctcaaccgga acagtcagct cccctgaggg ccgagccata ggcggccaat tccggtcaca
     2881 ccgtaagggg ttacgtgatg tgaccatacg tcacacaacc acaaccgccg gtgtacgctg
     2941 ccaactgaca gctcgccccg ttccgtaaac ggggcggccc ccggtggtgc gccaacaccg
     3001 tccgagggcc ttcaccacca aggtcaagaa gggaccctgg gatgttccgg catgttaccg
     3061 cgcccgcgcg ctacttctcc cagttgccga acgagatcat ccggcacccc cgcctcacct
     3121 cggacgccgt acgcctgctg gcctggcaac tctccctccc cggcggcgcg aacgagcccc
     3181 tgtcccgcac cgccgcccgc gccgggatcg ggaagaccgc cttccagcgc gccaagcggc
     3241 agctcctcga cgagggctac ctgcacgagt ggcggcggca gggcgaacgg ggccgctggc
     3301 gcaccgtaca gctgatctcc aacgtggtgg tgagtgcggc ggacgcacgc gcgctctggg
     3361 acggcggcat cgtgacggcg ccgaagccca cacagaaggc cacgcccgcg cccgtacccc
     3421 cagccgtacc ggccgcacag ccaccggcgg cggccctccc ggccgccggt ccgccgaccg
     3481 gccaggccgt cggccgtcaa ccccgtacaa acaccacgga gtacacaccc cacccacccg
     3541 acgacgcgtc ccggctcgcg gaggccgagg cgctgctgcg ttcgctgggc agtcacgagc
     3601 cgcggctcgt catgcccgca cgcaaggcac gcgcctgggc gcccctcgcc gccgagtggc
     3661 tggcctcctg cctctccccc gagctcatcc ggcagacgct cacgcacggc ctggacaagg
     3721 cccgttcacc gctgggcgcg ctgcgctggc gcctggagca cgccctgccc gagcagtcgt
     3781 acggcccacc gccgccacag ccgcgtgcgc cagagccgcg tatcgcccgg atgcgagagt
     3841 gcacgggcgc gcacacccag ccccgcctgt tcgcgccctc ctcggcggac gacgaactgt
     3901 gccccggctg ccgtgacacc ccgacggcag ccgcgccgcc gggtcccggc ctgcgcgcgt
     3961 tccgtacggc tcgcgccggc gcccgcacgg atacccggac gagcgcgaag acggcggtgt
     4021 ctgcgatggc ctgagcgcga cgtaccggcc aagctggcga gttctcaccc gtgatgccgt
     4081 tctccgccgc acaatggtgg gtccggtagg cgacgaactg gcgacgacgc gaggcgggga
     4141 cgacgggcag atggcgccgc agacaacgga acaggacgag gcggaacggc cgttcgccgc
     4201 ccagctcgag tccatgcgct ggacgcacgt gcgcggctcc gaactcaccg aggaggaccg
     4261 ggagccgggc catccgctgc tcactggtcg gctggccgaa gccgtacgcc gtatcaaccc
     4321 cgccacgccc cgccacgctg ccgacggcac gcccaccccg gcgagttcct ggctggacga
     4381 atccgctgtg ggggaagtgg tgggccggtt gcggcggctc gtggaacata cagacgggcc
     4441 gacgctcgaa gacgccaacc gggaggccac caggctgctc ctcggcggca cgacgatgcg
     4501 ggctccgagc ggcagggacg atccggtcca ctacatcgac tgggaaccag ggtcatcgcg
     4561 caacgacttc ctggccgtca gccagttcca agtccgtaca cccggcggcc gtacggcgac
     4621 gctcgacctc gtgctgttcg tcaacggcat cccgctggcc gtcgtcgagt gcaagagccc
     4681 ggacctcgcc gacccgctcg gtgacgcgat acgggacctg cgggcgtacg cgggaaggcc
     4741 cctggacacc gacgaacgcc ccggccggga acacccttgt ggcgtaccgg cggtgttcgc
     4801 caccgcgcaa ctgctggtgg cagcggacgg tacccaggcc gcgctcggca ccatctccgc
     4861 cgacgaggcg cactacgccg cctggcgcag cgtcaccccc gactacgagg acgacaaggc
     4921 gctgcaccgg gagatgcgtc gcgcccagca ggagtcgctg cccggcgaac gccacttcct
     4981 ggcggcgggc caggacatca acggacagca ccggctcatc gcgatcaccc tcaaccagcc
     5041 gaaccttctc aacatcgtcc ggcattacat ctgcgagctg ccggtgaaga acgacgccgg
     5101 cgaggtcgtc aagcgggtga aggcggtctg ccgccaccag cagtaccgcg ccgtggagaa
     5161 gatcgtgcac gggctgcgta cgcgcccctc tcggctcgca cccggtgccg tggaggacga
     5221 ccggggcggc gtggtctggc acacgcaggg ctcggggaag agcctcacca tggcgttcct
     5281 ggtgcggcgc ctgcatatga accgcgatcc cgcgctgaac gcgttcaccg tactggtgat
     5341 cacggaccgc aagcagcttc aggatcagct gtccgaggcg ttgcagcgca gcgaaagccc
     5401 tttgcagacg gccgagtcgc aggcggatgt cgagggaatg ctggagtatg cgggacgccc
     5461 cggtgggcgg atggtcgtct tcgcgatgat ccagaagtac ctgggacggg tgccgggcct
     5521 ggtcctggat gagacggccc gtgacgagcg gagcctggcg gacgacttcg aacaggcccg
     5581 tcaacgcatc gacgcgggcg aggacccggc tgacgtggtc gatccggttc cggccgagaa
     5641 cccggcccgg cgccgtgagt tcaggtggtg cagcgactcc gacaaggtgc tggtgctgat
     5701 cgacgaggca caccggtcgc acgcgtcggt gctgcacgcg tgtctgcggg acgcggtgcc
     5761 gaacgccgca cggatcggct tcaccggaac gcccatcctg cagggccgga agaagttgag
     5821 cagcgagatc ttcgggcgca ccatcgacgt ctaccgcatg gacgaggcgg aagcggacgg
     5881 tgtggtcgta ccggtgcggt acgagggccg tacgggcccg gcgcaggtga ccgagggcga
     5941 ggatctcaac accaggttcg cggacctcct cgccccgttg acggcgaagc agaaggaggc
     6001 actgcgcgga cgctggaacc ggcccaccgg gcgggatgtg gccgagtcgg tgccgatgat
     6061 ccgtgccaag gccgtcgaca tgctgatcca ctacgtgaag gggccgctgc gccggggctt
     6121 caaggcgcag gtagccgcgg tgagcaggga ggccgccgtt ctctaccggc acgcgctgcg
     6181 cgacgcgcgt gcggaactga tggcgcgtgt gcggagtttc gatccggacc ggctacgcgg
     6241 cgtggacccc agggactacc gggcctatcc gaaagacccg ttcaacgacg atctgctgct
     6301 gctgaaggcg tggcagttcc agcgggtgct gcgccggatc gacttcgtac cggtgatctc
     6361 ggccggcgtc gagcagaaga gcggacgctg gcgtgagtgg acggatccgg actgccaggc
     6421 cgagcacatc gcccgcttcc tccagccgct gcccacaccg ccgccggaga acccctgggc
     6481 gacggagcac ccggaggagg agagaaaagg cgacccgcca ccgctgggcg ggacgaatcc
     6541 gtggagcaag agcggtctgc ctccggcgct cgcggaggag ccccccgtcg ctttcctgat
     6601 cgtcaagtcc atgctgctga ccggcttcga cgcgcccgtg gagcaggctc tgtatctgga
     6661 ccggccgatc cgggacgcgg aactgctgca ggccgtggcc cgggtcaacc gccccgcgcc
     6721 ccgcaaggaa ctcggcctgg tggtggacta ctacggggtg ctgaaggatc tcaccgtcac
     6781 cctggccacg taccgcgatg acccgagtcc cgaggtccgt gagggcggga tgcgcgacat
     6841 ggccaccgaa gtacccggac tggaggctgc tgccgccgaa gtcgaacgct tcctgggaga
     6901 ccgggagatc accggcctgc acagccgcgc gggcatggtc aacgccatgc tgatgctggc
     6961 ggacgaggac gaccgtgctg aattcgaccg gctgctgagc gaattcatgc gctcgctgga
     7021 cagagtgctg ccgcacgaag ccgccttggg acatgtggcc gacgcgcagt ggtggacgct
     7081 gctgcagaaa cgcgtacgac gtctctaccg agacgcgccc gacggggact tctccctccg
     7141 cgcatacggc cgcgaggtcc gcgagatgat cgcggaccat ctgtcgctgc cgcagatcac
     7201 ccaggagatc gtgccggtct cgatcaacga ccctgagttc gacgcggcgg tcgagcgtct
     7261 cgcaaacgtg cggctggcag ctgcggagca gcagcacggc ctgcggtacc acctggaaca
     7321 gcacgagcgg cgggagcgtc cccagctcta cgaggaactg tccaaggagc tggaccgcgt
     7381 gctgcgagag ttcgacggcc gctgggagga gatgaaacgc gagctcggcg cgctgatcgt
     7441 acgagcgcgc cagcaggacg aggcgaatcc cgcgttggcc ggactgactc cggcggaacg
     7501 gctgatgcac gcccaactcg ctgacaggct cgcgcgggag ggcgacggcc tcgccctgcc
     7561 cgacgagcag ttgcgcgacc ttggtgtgca ggtgtgtgcc gcggtcaccg cacgggtcac
     7621 gctcgcctcg ttccggagtc aggagagcca cctcaccagc ctcgagacag agatcttcca
     7681 agccgtacgt ggagggctgc gcgcggcggg catccggacg gggacggagg tgcaccggaa
     7741 tatcgcgcga tcactggccg ggcacgtcca ggaacacctc ccccagtatc agcgggccag
     7801 cggcacgacg ggcggctggt gaaggtgcca cgggcggcgg caggcagcgg gttagattgg
     7861 accggtgccc ggaaccacca cactcctccg tgacggcggc gtcctgactc tggacggccg
     7921 tccgttcact gtacgggtga gcgcgcagcg taggcggctt ggactgacgg tggaacggga
     7981 cggctctctc accctccgtg tccctgaagg gtgtgagctc caccgcgcgg aagatttcgt
     8041 acgcgccagc cacagatgga tcgaggacaa gctccgtcta cggcaacgcc acctgccgtt
     8101 gaatcccgcg cgcgggctga cccacgggga ggtgttccgg tacctcggcc gggactaccg
     8161 gctggccttg gtggacacgg agggtgctcc tgtccgtctg cgccacggtg agctgctgct
     8221 ggaccgcggt ctggccagca gccgtcgctc ggcggtgcgc gcgctgaccg actggtacag
     8281 ccgtacaggg ctgcgctggg cgcaggggca cacgcaaccc tgggcggggc ggatggaggt
     8341 gccggagccg acgcttgagg tgagggacct gggccggcgc tggggcacgt accgttcggg
     8401 cgacggcgag gggaccggcg cgggacgcgt gtcgctgcac tgggccgtgt tccagctccc
     8461 gggcgcactc gtcgactacg tgatcgcgca cgaactggcc cacacgcgga tcgcggggca
     8521 cgggcccgac tactggcggc tacttggtcg tgccattccc gagtgccggt cacgcaaggc
     8581 cgaattggac gagatgggtc ggcgtgtgtg gctgggggat gtgagccggt agcgcggcgc
     8641 cctgcgtgac ccatcgctca gcccgtgcac ggttcgcaac gcggcggccg gcaggctgcg
     8701 atgaatcgcg ggcgctaatc ccgctccgtg ccgagcactt gggcccacca ggggtcggcc
     8761 ggtgcgcccg tgagggccac gcccatgtcg cggtaggcgc agtcgaggag gttcgcccgg
     8821 tgcgccgggc tgtccagcca ggcgtcgacg accgcggccg cgccggacgg cccgtgcgcg
     8881 aggttctccg ccagccgctc cgtgtcgtac ccggccgcct cggcgcgggc caggggctgc
     8941 gtgccgccgg cgccgacgtg ggtcagctcg cccgtacggt ccatgtgccc gctctgctcc
     9001 tcggccgcct cccgcagatc cggatccgta cggacggcgg ggcaaccggc ctccgtgcgg
     9061 tgctcgttca cgagggcgac gacctccgtc tcgacggcgg gcccggcgta cgccaccggc
     9121 gcggcgaagg cagccgatgc tgccgcggct ctcccgcgcg ccccgtccgc gcctcccccc
     9181 gcgcctcccc ccgcgccgct ctctgcgccg ccgccgtgcc cggcggccag cgccaggccg
     9241 cacagcaccg tcgccaccgc gcgtgccgcg ccgtcgcaca ccgaggtccc acgccactcc
     9301 accacgtatt ccgctccttt gtcccgcagc ccggctcccg gccgcaccat gcccgtcaac
     9361 cggggaagag tgccggagga accgaaccgg aaagcaactc gtcaaaggtt ccgattgagt
     9421 tcagcacggg tcaatacaac agtccccgga tttcccgtac acacgccttt cgagtgcact
     9481 actcttagca aatcccaccc ccacccggcg cctttcacat acggagtcct ttccgtacgc
     9541 ctttcacgcc cgcccctgcg caacccccgc caccgcacac caccggcgca cacccttgtc
     9601 gcgcgtaacc gaccggcggg tccgcacatt tggtggcctc ccgcaccact cgccccacgg
     9661 cgtgcacaca gcaacccgcc gtgcgccgcg catgtacgcc gtatacctcc gcattggtgc
     9721 gctgcccgtg ccaccccgcc accaagtgga gtggtttcag ggccggcagc gactgttccc
     9781 gcgaaacagc aggcatgctg cgattcggca caaccgcgga aaggccgcgc tgccaaccgt
     9841 gaaacggagg tcatcatgga aaaggtcacg acggaggtct acgagccccc cgcactggtc
     9901 ggaatcggcg agttcagcga agtgacgctg ggccccaaca acgacctgct cgttgactgg
     9961 gacggctact tcctctggta ctagacgcac aggagccggc atgggtgagg aatggttcgc
    10021 ggtcctcccg gacagcgaca ccggcctcgc cgcggcgcgc gctctgcgcc cgctggcgag
    10081 cgacgtcatc gaacacgcct ccgggcggcc ctggttgctg ggccggtggc cggagcggga
    10141 ggtgaccgtc gcgaccgcgg gcacggtgcg actggcggtg gccgggtgct ccccggccac
    10201 cgtcggatcg ctgcgcgagc ggctgcgcgg ggcccgttca gtgcacgaca tggacagaac
    10261 ggtggccagg ctgccgggct gcttccacct gctcgcctcg gtcgacggcc gggtgcgcgc
    10321 acagggcacg ctggcgtccg tacgccgcgt gttccacgca cgggtcggcg acgccgtgat
    10381 cgccgccgac tcggcgctcg tactggcccg gctgaccggt gccgactggg acccgtcctg
    10441 gctggcgctg cggctcgcca acatgaccgc gccgttcccg ctgcacgaga cgacgccgtg
    10501 gcgcggcgta cgagcggtgc ccggcgacca ctggctggag ctcgcccagg atggcaccgc
    10561 cgccgaacgg cgccgctgga ccgcgcccga gccggcgctg ccgctcaccg agggcgcacc
    10621 ggccgtacgg gacgcgctgg cggccgcggt gcagacccgt acgacgcacg gcggcacggt
    10681 cagtacggat ctgtccggcg gcatggactc cacgagcctc gcgttcctcg cgggccgcgg
    10741 cccggcgaag ctggtgacgt tccggatggc ggagcgggac gcgggcaacg acgacgcgta
    10801 cttcgccgac cgggccgcgg cgctcctccc gcgtgcgcac cacagggtgc accggccgga
    10861 ccgtacggcc gcgatgttcg ccgggctcgg gccggacacg gcggccgccg atccggaggc
    10921 gccgttcgcg tggatgcgca cgcgggcgcg gctcgcgcac gcggtgcggg cgatggccgc
    10981 ggagggttcg cgggtgcatc tggccgggca cggcggcgac gaactgttcc ggcccgacac
    11041 cacctacctc cacgacctgt tccgcgcgca cccgcgcacc gccctgcgct atctccgcgc
    11101 gcaccgcacg ctggggcgct ggtcggcgcc cgcgctggcg cgtgcgctcg ccgacagccg
    11161 tacgcccggt cacgaactcg ccgaccaggc cttacggttg cgggcgccgc ggcccggcct
    11221 gcggcacgtg tcgttcgcct ggtcgccgct gctgcggctg ccggactggg tgacggacga
    11281 cgccgccgag acggccggcg aactgctccg cgccatcgcc accgacccgg ccgaccccgt
    11341 cgaaccgctc gccgacgggc gcgcccagca cggcgtcgta ctgatggcac gctgcaccgg
    11401 cgcctccgta cgccaggcca accgcgtcaa cgcctccccc gcgtcctccg gcccgggagg
    11461 ctcccctggc ggcccgccgt tcgccgtgcc ctacctcgac gaccacgtgc tcagcgcggc
    11521 cctggcggtc cggctggagg accgcaactc gccgtggcgg ttcaagccgc tgctggcggc
    11581 ggccatgcgc ggcatcgttc cggaggaact gctgcaccgt acgaccaagg gcgcgttcgg
    11641 cgccgactac tacgcgggcc tgcgccgcca ccgcgccgaa ctgctcgccc tgttcgacgg
    11701 atcggagctg gcccggcacg gcctgatcga cgacgcgacg ctgcggcgcg cactgctgcg
    11761 cccgcacaag gacaacaccg ccctgtcggg gctcgacgcc accctggcct gcgaggcgtg
    11821 gctgcgctcc ctcaacgccc gtgccactgc cggaccccac accggcagtg gcacggtgcc
    11881 cgaccccgtt ccgcactgaa ccgagagacg catgggctgc catgaccacg acctcgtcca
    11941 caccgtcctc ctcatccgcc tcgccggatc cgctcacgcc gctcgtcctg cggccgcaca
    12001 tcaccgcgac gcctacggcc gacggcatgg tgctgctgga ccagcgcacc ggcgcgtact
    12061 ggcagatgaa caccaccgcg accctcgtcc tgcacgccct gctggacggc gcggacgccg
    12121 agcaggccgc cgccctgctg gccgcccgtc atccggcggc cgccgaacgc gcggacagcg
    12181 acgtcgccgc gctgatccgg cagctgcacg acgcagggct ggcgcagccg cgcgacggcg
    12241 cacgggaacg aggtccgggc cgcggcagcg gcagcggacc gaacaggaac cggaaccgcg
    12301 accggacgca gaaccggaag ccggaccagg agagccgcac atgagctacg acgtcgtcct
    12361 ccccacccac gaccggctgc ccttccgccg ccgcccgtcc gccctcctcg cggtcgccgc
    12421 cgcccgcctg ctcgccacgc tgccgccgta ccgcatcggc caggtgctcc gtacgctgcg
    12481 ccgccgcgcc gcacccgcca ccgccgggca ggcgagcaac gcgcggctgg ccgtggtcac
    12541 cgtcagccgc cggtgcacca gcccgcaggg ctgtctgcag cgttccctgg ccaccgccct
    12601 gctgtgccgg ctgcggggcg tgtggccgac gtggtgcacg ggcgtacgca cccagccgtt
    12661 ctccgcgcac gcctgggtcg cggtggacgg cacgccgata gacgaaccgc aggccgcgga
    12721 ctactacacg ccggtgctgg ccgtcccgcc gcggaggcgc ccgtgaccac ccgcccccgc
    12781 acctccccgg cgcggcggac cacctccgcg gacgggcggg agcgcgaacc cggccaggag
    12841 caggggcacg agcaggggca cgagcacggg cacgggcacg ggcacgagcc ggggcacccg
    12901 tacgcgatcc acgcccgcgc cctcgccaag tcgtacccgg gcggcaccga ggccgtacgc
    12961 ggcgtggacc tcgccgtacg ccccggcgag accttcgcgt tcctcggccc gaacggcgcc
    13021 ggcaagtcca ccaccatctc cctcctgtgc gcgctggccc gccccaccgc cggcgaagcg
    13081 cacgtgtgcg gcgcggacgt ccgtacggag ccgcagcgcg tacgccgcac cgtcggcctg
    13141 ctgttccagc acagcgcgct ggactcgaat ctgacggcgc gccagaacct ctacgtgcac
    13201 gcccgcctgt acggcctgtc ccgcgcggca gcgggggcgc gcggggcgga gctgctggcg
    13261 ctcgccggtc tcgacgaccg gcagcgcgcg ccggtgcgca ccctgtccgg cggcatgcgc
    13321 cggaggctgg agatcgcgcg ggccctgctg cacgacccgc gcgtgctgtt cctggacgag
    13381 ccgaccgtcg gcctcgaccc gcacgcgcgg gcccagatct gggaccacct gcacgcgttg
    13441 cgcgccgagc ggcgtacgac gctgttcctc accacccact acctggagga ggccgagcac
    13501 tgcgaccgca tcgccatcat cgacgcgggc cgcgtcgtcg ccgagggccc gccgcgcgaa
    13561 ctgaaggcgg agatcgccga cgaccgactc cggctgcgta cgtccgacga cgcggcgacg
    13621 gccggcatcc tgcgggacac cttcgggctg agcccggcgg tggcggggga cgccgccgta
    13681 cccgacgagg ccgacgcggg cgtcaccgta cgggtcggtg agggcgccac gtggattccg
    13741 cagctgtgcg tggcgctcgc cgcgcgggac atcgcggtgc acgcggtgtc cacgacgccg
    13801 cccaccctgg acgacgtgtt cttccaccac acgggacgca gcatccgcgc ctgacggcgg
    13861 caccgccgtc gccacggtgg ttcagccgcc cggggtgagg gggccgggcg gcgggccgct
    13921 gccgcgccgc ccggcccgcc cctcacacct gccgctgcct cttcacacct gccgctgcag
    13981 agccttctcg cgcccggcgg ccacggccgc gccggactcc cgccgcgcca tccggcgcag
    14041 tacggcgggc gccgtcagca ggcccacgac cgcccacacg ccgagcacac cggccgtctc
    14101 caagtgccgc cacgagtcgc cggcttccgc cgccgccagc gcgtccggca gcagcgccga
    14161 acgcagcccc agccccagcc agtacacggg gaacacctgc gccaccagct gcagccagcc
    14221 gggcagcgcc gtgaccgggt agaacacacc cgagaccccc accagcccca tcatcaggag
    14281 ccacacgaaa ccgaggctct gcacgctgcc ggccagcgcc ccggccatcg ccccgagcgg
    14341 cagcgtcgca gccagcccca gcgccagcac ccaggccagc gtcagccacg acgccgcgcc
    14401 gcccagctcc atgccgtcga agaggaacgc cgccggcacc agcgccacga acaggctcac
    14461 gacggtgacc gcggcccgcg agaccacctt gccggtcaga tagccgggca cgccgttcgg
    14521 tgtcgccttc gcgcgcagca ccgtgccgtc ctcgcggtcc atggcgaggg ccatggccag
    14581 cccgaccagc ccggtgagca ccacgttcag cccgaggatg cccggcacgg actgcgtgcc
    14641 cagcgagaag tccgtgccgg gcaccgtgct gtcccgcagc acgtacatca cgatcagcga
    14701 gacgacgggc gtgaacagcg ccgaccagat gtcctgcccg ctcgtcgcgt actgcctgaa
    14761 ctcgatgcgt ccgcgctgca gtccggcgcg tacggccacc gcggtgcccg cgttcacggc
    14821 gccacctccg tcgcgtccgc cacagccgcc gcgtccgcca cagccgccgc ctgtgacgtg
    14881 gccgtcagct ccgcgggggc cgccgtacgc tgcccggact cgaagtcccg taccagcgcc
    14941 aggtagacgt cctccagccg cgcccggcgc acctccagct cgccgatgcc cgcgccgtgg
    15001 cgggcgaaca gcccgcgcac gtactccgta ccgtccggca cggaccgtac gtacgactcg
    15061 ccgtccctgc tgaagcggac ctcgtccgcg cccgcgaccc gccgcgccag ctccgccggg
    15121 ctgccctccg cgacgacccg gccgcccgcc aggatcacga tgcggtccga cagcttctcc
    15181 gcctcgtcca ggtcgtgcgt ggtcagcagg atcgtcgtgt cctccgccgc ggccagccgg
    15241 tgcaccagtt cgtggaactc ctgccgcccc tgcgggtcga agcccaccgt cggctcgtcc
    15301 aggaacagca gctccggcct gccgaccagc cccacggcca cgtccagcct gcgccgctgc
    15361 ccgccggaga gcgtgccgac cgtactgccc gcccgcccgg acaggccgac gagggcgatg
    15421 agttcgtccg tgtcgtacgg gcgggggcgc tccggagtgc cgtacggcgc gtagaagcgc
    15481 ccgaggtggt ccagcaactc ccgtacgcgc cacttgccgt ggtcgcgcca cgactgcagc
    15541 acgacaccga gacgggcacg ccacgcctcg tcaccgtgct cggggtcgct gccgagcacc
    15601 cgtacgtcgc ccgccgaacg gtgccggaac ccctccagga tctcgatggt cgtcgtcttg
    15661 cccgccccgt tcggcccgag cagggccagc acctcgccgc ggtcgagccg gaggtcgacg
    15721 ccgtcgaggg cgtcggtggt gccgtagcgc atgcgcagtc cgcgcacctc gaccaccggg
    15781 cggttcccgt cgttcctgtc gctgacattc ataccttcaa gtgtttcatt gaagtgcttg
    15841 tggggacttt tgtgcgctgc ggccgcggta cggtgggcag ttgagccgta aaccctcaaa
    15901 ccggggtgga acccatgagc tgtcaaggcg cggagctgcg ccccgtcgac ctggcgcgcg
    15961 aggccggtgt ctccacccag ctcgtccgca actacgagga cgccggcatc ctgcccccgg
    16021 cacggcgtac gccctccggc taccgcaggc tcgaggaccg gcaccggcgg gcgctgctca
    16081 cgtaccgggc cctcgcccgg gggtacggga cggccgccgc ccgttcgatc atgcgggcgg
    16141 tgcacgacgg ggacctgccg cgcgccctca cccacgtgaa cgccgcccac gccgaactgc
    16201 acgagcagca gcgcgcgctg cgcgccacgg gcgaggcgct ggaggccgtc gcggaacagg
    16261 acgtggagca gggcgtggag cagggcgtgg agtccgcgga gccggcgcag tcccccaccg
    16321 gcctgcgcat cggagaggtg gcggcgcacc tcggcgtacg cacctccgcg ctgcgcgtgt
    16381 gggaatccgc cgggctgctc acgccgcagc gcacgccggg cacgtcgtac cggctgtacg
    16441 gcccggccga cgtacgggac gcgcgcatga tccacatgct ccgccagagc cactacccgc
    16501 tgccccagat cggccccgtc ctggacgacc tccgccaggc cggcagcggc gacgcgctcc
    16561 gcgcggccct cgcccggcgc caggagagcc tgacggcgcg ggcgaccgcc atgctggagg
    16621 gctccggaca cctgcaccag tacgtcacgg cgggcgcgta ggggcggggg cggcggactg
    16681 cggcggcgcc ggggggcgtg cggcccgggg cgcgcggccc gctccccgcg cgggatccgg
    16741 cgcggcgccc taccgtggtg agcgtggcca ggtcacgcag gaacggcggg caccgcaggt
    16801 ccgggggcga ccgcccggtg ctggcgttca acccgatgtt cgcctcggaa ccgcccgagg
    16861 tgccgcgaga ggcgcttcca gacggcgaga tggacccgga actggcgtac cagatcgtcc
    16921 acgacgagct catgctcgac ggcaacgccc ggctgaacct cgccaccttc gtcaccacgt
    16981 ggatggagcc ccaggccgac cgcctcatgg ccgagtgctt cgacaagaac gtgatcgaca
    17041 aggacgagta cccgcgtacg gccgccctgg agcaacgctg cgtacggatg ctcgccgagc
    17101 tgtggcacgc gcccgagccc gccgaggcac ccggctgctc caccaccggc tccagcgagg
    17161 cctgcatgct ggccgggctg gcgctgaaac ggcgctggca gcaggcccgt acgcgcgcgg
    17221 gcgtacacgt acgcccgccg gccgggcggc ccaacctggt gatgggcgcg aacgtgcaga
    17281 tctgctggga caagttcgcc gcgtactggg acgtcgaacc ccgcctcgtc cccatggagg
    17341 gcgaccggct ccacctgacc gccgaacagg ccgtcgcaca ctgcgacgag aacacgatcg
    17401 gcgtcgtcgc cgtcctcggc tccaccttcg acggcagcta cgagcccgtc gcggacatct
    17461 gcgccgcgct cgacacgctg cagcgggaga ccgggctcga catccccgta cacgtcgacg
    17521 gcgcgtccgg agcgatgatc gccccgttct gcgacccgca cctggactgg gacttccggc
    17581 tgccgcgcgt cgcctcggtc aacacctcgg ggcacaagta cgggctggtc taccccggcg
    17641 tcggctggat cgtctggcgc gacacggcgg cactgccgga cgacctggtc ttccgggtca
    17701 actacctcgg cggcgacatg ccgacgttcg ccctcaactt ctcccgcccc ggcgcccagg
    17761 tcgccgccca gtactacacg ttcctccgcc tcggcttcga cggctaccgc cgcgttcagg
    17821 actactgccg cgacgtcgcc acgacgctcg cctcccgcat cggccacctc ggcccgttcc
    17881 ggctgctcac ccacggggac gaactccccg tcttcgcctg cgcgctgcgc ccggagatcg
    17941 cgggctactc ggtcttcgac gtctcggccc acctgcgcca acgcggctgg ctcgtcccgg
    18001 cgtacacctt cccggaacac cgtacggacc tcgccgccct ccgcttcgtc gtacgcaacg
    18061 ggctgacaca cgacctcgcc gacctgctcc tggacgacct gcgctgggcc ctcacggagc
    18121 tggaacgcca gcccgccccg ctccgcggcc cggaatccgc ctccttcgcc cacggcaacc
    18181 gcccccgcgc ctgaccccgt acgaccgccg gagaccgcgc cgggcgggcg ggagaggggt
    18241 ggtcctacgt tgttgatggg tcggatgggc tgtcgtacgg tccggaggat ccagtggccc
    18301 tgggtatggc ttgggggtgg ttgccttgtg atggctccct gtgacacctg gccgcccggg
    18361 gcggtcgtgg acggacgggg aaggggagga gacggggaag gggcggccgg tgcggcggcg
    18421 tgacgcggcc gtaccggtgg ccaccgtctc agtgttcagc tgcgaagggg aatgcccacc
    18481 gccacacccc ggaatcggcg atagtgggag ccgatcagtg agccaatggg tgagtcggag
    18541 cgggtccggc ggacaccgtg agcggtaccc cgggaacgcg gtctcatggc cggcgttctg
    18601 tcgagaacaa cgtgtggagg acgcgaaatg agccagcagg acgccgtact cggtgagcag
    18661 cagcggcagc tggagcccat gccggaggac tgggggcgcg ccctcgcggt ggtcgcacac
    18721 ccggacgacc tcgagtacgg cgcggccgcc gccatcgccg aatggaccac cgccggacgg
    18781 gagatcggct acctgctggt gacgcgcggc gaggcgggta tcgacgggct ggagccgggc
    18841 gagtccgcac gggtgcgcga ggcggagcag ctggccagcg cgggcgtcgt gggggtcggc
    18901 gacgtgaagt tcctggacca caaggacggc gtgatcgagg agggcgtcgc gctgcgccgg
    18961 gacatcgcgg gggccgtgcg cgcgttccgg cccgagctgg tgatcaccct caaccaccac
    19021 gacaccttcg gcggcgtcgc ctggaacacc ccggaccacc gcgccgtggg ccgcgccacg
    19081 ctggacgcgg tcggggacgc cggcaaccgg tggatcttca ccgagcagct ggagctggag
    19141 ggcgtggagc cctggggcgg ggtgcgctgg gtcgcggtgg cggcgtcgcc ggagccgacg
    19201 cacgcggtgg cggtcgggga cgagtcggtc gagcgcgccg tggcctcgct ggcggagcac
    19261 cgcgcgtatc tcacggcgct cagcgaccag gagccggcgg cgtacgcgcg gtcgttcctg
    19321 gtgccggcga tggagcaggt gggggagcgg ttcgggggca agcggggggt gtcgttccag
    19381 ctctacccgc gctgagacgg agggggcgat tccgcggccg gcggcgcgag ggccgcggcg
    19441 tccgcggccg gtccggcttc gctgcccgta cggtcaggcc cgccctcgcg cgtacggtca
    19501 ggcccgccct cgcgcgtacg gtccgttccg tttccgcgcg tacggtcccg cgccccctcg
    19561 cgcgtacggg ccgccgcccg ccggagcgtg ccggcgaagg ccagcgcggc cacgggcagc
    19621 aggagcgccg cggagaccgc ggtgagccac ccgtaaccgg cctgggagac gatcactccg
    19681 gccagtgcgc cgcccgcgcc ggccgccgcg ttcatcgtca ggtccgacag gccctgtacg
    19741 gcggcgcgtg cgggctgcgg cacggagtcg gtgagcagcg cggagcccgc gacgagggcc
    19801 gctgaccagc cgagaccgag cagtgcgagg ccggcggccg accgcgagtg gtcggcgccg
    19861 gccgtacccg cgagggccgc ggcgcagacg agcaggccga tcgcgaggcc gatgacgctg
    19921 agccggccga gccggtcggc gagccagccc atgacgggcg acagcgcgta catgcccgcg
    19981 atgtggccgc tgatcaccag cccgatcagg tcgatgtccg cgccgtgatg gctcagcgcg
    20041 acgggcgtca tcaccatgat cgagaccatc accgtgtgcg cgcccgcgat cgtcaccagc
    20101 gccagccggg cgcgcggcga ggcggcgacc gcggccatgc ccgcccgtag cgaacggccg
    20161 tcctccgcgg gcggcttccc cgtaccggcc gattcctcgg cctcccgggc ggccagcgcg
    20221 cgggcggtca gcagcgggtc cgggcgcagc agcagctgca ccagcgcgcc cgcgatcagg
    20281 aagatgccgg tgccccacag gaacgggccc gccgtcgcgg gtatcccgag ccccagggcg
    20341 gagacgctgc gcccggcggg ggcggcgatg ttcgggccga gtacggcgcc gatggtggtg
    20401 gcccagacga cggtggagat cgcgcgggcg cggcgatccg gctccgcgag gtcggcggcg
    20461 gcgaaccgcg cctggaggtt ggccgaggag cccgcgccga acgccgccat cccggccagc
    20521 agcaccggga agttctccag catcgccccg acgaccacgg tcgcgccgcc cacggcggcg
    20581 atcaggtagg cgagcgcgag gccggggcgg cggcccttcg cggccatcag cgcggcgagc
    20641 gggagcgaca gcacggcggt accgacgacg gacgaggtgg aggccagccc ggcgagcccc
    20701 tccgaaccgc tgatgtcctc ggccagtacg gcggccagcg cgatgccggt ggcgacgccg
    20761 aggccgccga gtatctggct cacgaccagc acggcgtgca cgcggcggcg cagcgcggcc
    20821 aggccctccg ggcccggcgg tgcggcggcc cgcggctccg tggccgccga gtccgtggcc
    20881 gccggtttcc tgtcaggagc gtcggcggaa tcgcgggtgt cggtcacggc cggtcagtct
    20941 gccagcccgg aatcgggtgc gccaggtcac aaaaaagagc gtgcgccagg tcacagaatt
    21001 cgggtgcgcc aggtcacaga aaggggcccg cgcggtcttc tctgtcgctc cggctggtga
    21061 ggtgcggcac agccttttcg tgactacgag ccggaatagg aagcccgtgg gaccaaagtc
    21121 ccggaccttc ggtccggccg ggtggtgacc tcgggcggtg cggcacggtg cccggaaagt
    21181 ccgattgtgc cagttcaggt gcggggtggg ggagaaaggt cctccggcga ccgggcgcgg
    21241 aatccgccgg tgcccgcgta aaaggacgcc attctcctca ttcggatacg gggcggccta
    21301 gtatccgccg gttttgggcg gggccggaat gtcgcgttac caaggtggag ccctgctcgc
    21361 agtcagggat tacccagaat tcttcggagg tagcaccggc atgcccaaaa aggtctcgct
    21421 caccacgctc atgaaccatc cccgcggtca ggtcgcgctt ctcgcctcgg gcctgtgcgc
    21481 ctccctggcg ctcggggccg gcgtcgcggc cgcggccgag cagcccgcgg cccccgcacc
    21541 caaggacgcg tttgcggcga gtgcggccgg tgacctggcc aaggccacca agcagcagtc
    21601 cgacgcgcag tacaaggccg ccgaggccgg cgccaagaag gcggcggacg acaagaaggc
    21661 cgccgcgaag aaggcggcgt cctgggtcaa gccggtctcg aagccgtaca cactgaccgc
    21721 gtccttcggc aacagcggcg accgctggtc ggccaagcac tccgggcagg acttcgccgt
    21781 cccgacgggc acgcccgtca agtccgtgca caagggcacc gtggtcgagg ccgggaacgg
    21841 cggcgcgtac ggcaacaacg tcgtgatcga gcacccgaac ggcaagtaca gccagtacgc
    21901 ccacctgtcg aagatcaacg tgcaggtcgg ccaggacgtg aacaccggca cccggatagc
    21961 caactccggc aactccggca acacctccgg cccgcacctc cacttcgaga tccggaccac
    22021 cgccgcgtac ggctccggct tcgacccgat gccgttcctg cacaagcacg gcgtgaaggt
    22081 ctgacggatc cgacggaacc cggccggggg cgcacgctga accagccccc ggtacagccg
    22141 ctccgtacgg aagcacggcc ttccgtacgg gagcacaccc ccgtacggaa gcggctcacg
    22201 ctagaacagc ggctccggga gcacgccctc cagtgccagc agcgtccgct tggtctcgag
    22261 tccgccgccg aacccgccta tgccaccgcc gctctccacg acgcggtggc agggcacgac
    22321 gacaggcagc ggattcgcgg ccatcgcgac gcccacggcg cgggccgcgc ccggctcgcc
    22381 gacccggtcg gcgaggtcct ggtacccgac ggtcgcgccg taccgcacgc cggtggccag
    22441 ctcccgcagc acccgctcgt tgaagccgcc ggtcagtgac cagtccagcg ggagcgtgaa
    22501 cgtccgcagg gtgcccgcga agtacgcgtc cagctgctcg gccgcctcag ccagccgggc
    22561 aagcggcccg gccggagcgc cggagccact ggatatgccg gatatgtcgg cgccgtccgg
    22621 ggtgtccgcg ccgtctccca cggcgggccc gaaccggccg cgcagccggg tcagcgcgcg
    22681 ctcggtgatg tccgggccgg cgtggaagac gacctgtatg agcccctcac cggtcgccgc
    22741 cagcagcagc ggtccgatgg gggcgt
//
