MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
ALJ99879.1 FlsR3 BGC0001904.2 PKS:Type II aromatic 44.0 84.6 191.0 3.21e-60
AEE65494.1 response_regulator BGC0000223.5 PKS:Type II 45.0 84.6 190.0 4.54e-60
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 43.0 86.1 188.0 3.39e-59
QCT05734.1 Tri1 BGC0001983.3 other:other 46.0 84.2 184.0 1.04e-57
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 47.0 85.3 178.0 3.12e-55
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 45.0 87.6 174.0 2.36e-53
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 46.0 87.6 172.0 8.83e-53
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 46.0 83.8 170.0 4.56e-52
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 42.0 84.2 169.0 1.21e-51
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 44.0 85.3 166.0 1.36e-50
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 45.0 83.8 166.0 3.11e-50
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 44.0 83.8 162.0 3.24e-49
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 44.0 83.8 162.0 3.24e-49
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 44.0 83.8 159.0 4.56e-48
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 45.0 83.1 160.0 7.35e-48
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 44.0 86.8 158.0 1.32e-47
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 38.0 86.5 157.0 3.82e-47
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 35.0 87.2 155.0 2.93e-46
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 44.0 82.7 154.0 3.21e-46
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 43.0 82.0 154.0 4.28e-46
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 43.0 83.8 152.0 3.02e-45
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 42.0 89.1 153.0 3.61e-45
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 42.0 85.7 151.0 8.72e-45
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 36.0 84.6 151.0 1.12e-44
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 38.0 86.1 149.0 5.3e-44
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 40.0 84.6 145.0 2.75e-42
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 41.0 82.7 144.0 4.5e-42
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 37.0 86.1 144.0 8.58e-42
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 41.0 82.3 144.0 9.31e-42
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 39.0 83.1 144.0 1.62e-41
AVO00817.1 May18 BGC0001661.5 PKS 40.0 85.7 142.0 2.25e-41
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 40.0 83.1 141.0 3.78e-41
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 39.0 83.5 144.0 3.98e-41
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 41.0 83.5 141.0 7.62e-41
AAL15604.1 Sim1 BGC0000270.5 PKS 37.0 86.5 141.0 9.24e-41
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 40.0 83.1 140.0 2.87e-40
AAK06808.1 putative_regulator_SimReg1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 38.0 86.8 139.0 1.01e-39
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 40.0 85.0 139.0 1.11e-39
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 36.0 86.8 138.0 1.25e-39
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 39.0 82.7 138.0 1.51e-39
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 37.0 84.2 137.0 2.41e-39
AFI57015.1 QmnRg3 BGC0000133.5 PKS 41.0 83.5 137.0 2.6e-39
ABB69091.1 hypothetical_protein BGC0000260.3 PKS 35.0 86.5 137.0 4.08e-39
ALJ99857.1 FlsR1 BGC0001904.2 PKS:Type II aromatic 42.0 78.2 134.0 1.38e-38
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 37.0 83.1 136.0 2.18e-38
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 33.0 83.8 134.0 2.71e-38
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 40.0 83.5 133.0 6.97e-38
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 37.0 83.1 134.0 9.57e-38
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 37.0 84.6 132.0 2.29e-37
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 38.0 83.5 131.0 3.49e-37
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 38.0 83.5 131.0 3.49e-37
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 37.0 83.5 132.0 3.63e-37
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 37.0 83.5 132.0 3.63e-37
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 36.0 83.5 131.0 1.17e-36
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 37.0 88.3 130.0 2.13e-36
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 36.0 83.1 128.0 5.09e-36
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 37.0 83.5 127.0 1.46e-35
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 40.0 83.8 125.0 6.51e-35
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 33.0 85.7 125.0 7.04e-35
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 35.0 86.5 125.0 1.09e-34
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 34.0 83.1 123.0 5.59e-34
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 33.0 85.7 122.0 7.66e-34
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 36.0 83.5 120.0 5.55e-33
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 39.0 83.5 119.0 1.08e-32
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 36.0 83.8 118.0 5.83e-32
AEA29625.1 Por2 BGC0000409.5 NRPS:Type I 36.0 82.0 117.0 7.6e-32
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 33.0 85.7 116.0 2.26e-31
ADB02841.1 AzicR3 BGC0000202.5 PKS 35.0 86.1 116.0 3.1e-31
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 38.0 83.5 114.0 1.9e-30
WP_082320004.1 response_regulator_transcription_factor BGC0002012.4 PKS 34.0 83.5 114.0 5.78e-30
QNL10611.1 Response_regulator BGC0002514.3 PKS 35.0 78.9 111.0 1.35e-29
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 32.0 83.5 110.0 5.6e-29
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 28.0 84.6 107.0 1.1e-27
QUS58949.1 response_regulator_transcription_factor BGC0002123.3 NRPS:Type I+PKS:Trans-AT type I 33.0 83.8 104.0 6.45e-27
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 29.0 85.3 104.0 1.06e-26
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 28.0 84.6 103.0 1.62e-26
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 28.0 85.7 102.0 4.06e-26
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 42.0 46.6 97.0 9.75e-25
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 27.0 85.0 99.0 1.61e-24
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 47.0 44.4 95.0 4.67e-24
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 36.0 46.2 83.0 5.03e-18
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 35.0 47.7 79.0 1.56e-17
BAW35603.1 putative_DNA-binding_response_regulator BGC0002357.3 PKS+other:other 36.0 47.0 74.0 2.22e-15
ABK32284.1 Jer4 BGC0000080.5 PKS 36.0 43.6 74.0 1.56e-14
ABK32252.1 Amb4 BGC0000014.5 PKS 36.0 43.6 73.0 2.11e-14
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 36.0 44.4 70.0 5.4e-14
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 36.0 41.4 72.0 6.37e-14
AUA09456.1 Transcriptional_regulatory_protein_LiaR BGC0002291.3 PKS 37.0 44.0 70.0 6.56e-14
QDF63356.1 KyaR BGC0002346.3 ribosomal:RiPP 33.0 79.7 69.0 8.39e-14
ACN39724.1 SibA BGC0000428.5 NRPS:Type I 41.0 36.1 69.0 2.21e-13
ctg1_orf18 BGC0000053.5 PKS 36.0 44.0 67.0 4.38e-13
ADB02831.1 AzicR2 BGC0000202.5 PKS 32.0 60.2 66.0 1.04e-12
WP_030193597.1 response_regulator_transcription_factor BGC0002669.2 ribosomal:RiPP 33.0 60.5 65.0 3.63e-12
ABK32275.1 Amb7 BGC0000014.5 PKS 31.0 45.5 67.0 3.7e-12
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 30.0 69.2 65.0 4.4e-12
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 34.0 45.1 63.0 1.26e-11
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 33.0 41.4 63.0 1.83e-11
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 31.0 78.6 62.0 5.19e-11
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 36.0 45.1 62.0 5.57e-11
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 30.0 52.6 61.0 1.06e-10
BCD33686.1 bacterial_regulatory_proteins,_luxR_family BGC0002448.2 NRPS:Type I 33.0 44.0 59.0 5.73e-10
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 30.0 43.6 57.0 1.48e-09
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 31.0 44.4 57.0 1.62e-09
ALV82366.1 regulator BGC0001370.4 NRPS:Type I 32.0 43.6 57.0 2.09e-09
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 30.0 41.0 56.0 3.87e-09
AAZ23070.1 possible_response_regulator BGC0000291.5 NRPS:Type I 28.0 80.1 56.0 8.55e-09
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 28.0 43.6 55.0 9.51e-09
CAB38597.1 two_component_system_response_regulator BGC0000315.5 NRPS:Type I 31.0 43.6 55.0 9.7e-09
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 27.0 85.3 54.0 3.39e-08
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 27.0 90.2 53.0 4.47e-08
BBA21064.1 putative_two-component_response_regulator BGC0001740.5 NRPS:Type I+PKS 38.0 31.6 50.0 1.03e-07
QHZ32201.1 response_regulator_transcription_factor BGC0002307.3 ribosomal:RiPP 30.0 47.4 52.0 1.13e-07
SFF02396.1 two_component_transcriptional_regulator,_LuxR_family BGC0001674.5 ribosomal:RiPP 28.0 85.0 51.0 2.07e-07
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 33.0 45.5 51.0 2.81e-07
BBD82049.1 LuxR_family_transcriptional_regulator BGC0001920.4 ribosomal:RiPP 28.0 85.0 51.0 2.81e-07
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 28.0 86.5 50.0 3.6e-07
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 29.0 45.1 50.0 3.67e-07
ACR33059.1 response_regulator BGC0000495.5 ribosomal:RiPP:Lanthipeptide 26.0 87.6 50.0 4.96e-07
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 29.0 45.1 50.0 4.96e-07
AAP03103.1 putative_2-component_system_response_regulator BGC0000874.5 other:other 27.0 86.8 50.0 6.83e-07
ACI88882.1 AlnR5_two_component_response_regulator BGC0000195.5 PKS:Type II 30.0 43.6 49.0 1.03e-06
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 28.0 45.1 49.0 1.75e-06
ARF06225.1 LuxR_family_transcriptional_regulator BGC0001593.5 NRPS:Type I 32.0 44.0 49.0 1.89e-06
AFL68048.1 response_regulator_with_CheY-like_receiver_domain_and_winged-helix_DNA-binding_domain BGC0001524.3 NRPS:Type I+PKS 31.0 38.0 47.0 7.04e-06