LOCUS       NZ_CP031263            20951 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Micromonospora aurantiaca strain 110B(2018) chromosome, complete
            genome.
ACCESSION   NZ_CP031263
VERSION     NZ_CP031263.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora aurantiaca
  ORGANISM  Micromonospora aurantiaca
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7255264)
  AUTHORS   Wang,R.
  TITLE     Streptomyces kandeliansis sp. nov., an endophytic bacterium isolated
            from mangrove plant
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7255264)
  AUTHORS   Ye,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JUL-2018) Ocean College, Zhejiang University, Zhedalu,
            Zhoushan, Zhejiang 316000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUL-2018
            Assembly Method                   :: ABySS v. 1.5.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003351365.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 12:17:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,622
            CDSs (total)                      :: 6,558
            Genes (coding)                    :: 6,457
            CDSs (with protein)               :: 6,457
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 49 of 101
            Pseudo Genes (incomplete)         :: 65 of 101
            Pseudo Genes (internal stop)      :: 6 of 101
            Pseudo Genes (multiple problems)  :: 18 of 101
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6892081
            Orig. end                         :: 6913032
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031263.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Min Wu.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20951
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20951
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20951
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10951](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10951
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    369..383
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            complement(<433..1083)
                     /locus_tag="DVH21_RS33950"
                     /pseudo=""
     CDS             complement(<433..1083)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037778.4"
                     /locus_tag="DVH21_RS33950"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="phosphoribosyl-AMP cyclohydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLRGSHARRAATEHSDVDVDVLVVADDGRTAGTGARQAASRRGTP
                     YAARRAYLTEFAGRLVHVSVAARDVRSWVRRLGQPADWAFGLPVTAPARLLWAVPEWRR
                     RIDLPVLCQPADEPRLEELIATLGKVAAARVADDPVGVRLAAADLARLCPSVLRPANPS
                     VRVVSRRAALTAALDLPVAPPGYRHDMLLCLGLRAGDPAEVGAAAGRLVTGILP"
     gene            complement(1246..1635)
                     /locus_tag="DVH21_RS31195"
                     /old_locus_tag="DVH21_31195"
     CDS             complement(1246..1635)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1171:
                     transcriptional regulator, MerR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287558.1"
                     /locus_tag="DVH21_RS31195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31195"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_013287558.1"
                     /transl_table=11
                     /translation="MDISTREMSLTVGEAAERVGLTTYTLRWYEQEGLVGRVGRDSSGR
                     RRYTESDVNWLFLLTRLRRTGMPVRDMRRYAELARHGDSTLGARRALFEAHRARVLARM
                     AELEEDLKVLEHKIDAYRRAEEESG"
     misc_feature    complement(1681..1699)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.27"
                     /tool="antismash"
     misc_feature    complement(1682..1698)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.6"
                     /tool="antismash"
     gene            1746..2468
                     /locus_tag="DVH21_RS31200"
                     /old_locus_tag="DVH21_31200"
     CDS             1746..2468
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287559.1"
                     /locus_tag="DVH21_RS31200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31200"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_013287559.1"
                     /transl_table=11
                     /translation="MDDAVSVRELVVDRGGRRVLHGISCEVPRGTVTGLLGPSGSGKTT
                     LMRAVVGVQTVGSGTVDVLGRPAGSADLRRRVGYLTQAPSVYADLTVRENARYFAVLQG
                     RGRAEADRAVADVGLAEAADQLVGTLSGGQRSRASLACALVGEPELVILDEPTVGQDPV
                     LRADLWARFHAMAANGTTLLVSSHVMDEAARCDRLLLIREGRLVADDTPAAVRAATGTD
                     DLEEAFLRLIRDAEGEAR"
     gene            2465..3220
                     /locus_tag="DVH21_RS31205"
                     /old_locus_tag="DVH21_31205"
     CDS             2465..3220
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014389.1"
                     /locus_tag="DVH21_RS31205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31205"
                     /product="ABC transporter permease"
                     /protein_id="WP_013287560.1"
                     /transl_table=11
                     /translation="MNGRILAATTGRILRQLRHDRRTVALLVVVPSVLLTLVYFMYVDQ
                     PAPPGGPSTFDRVALIMLGFFPFIIMFLVTSIAMLRERTTGTLERLLTTPLGKLDLLFG
                     YGIAFGLAGVLQSTVASVVAYRVFGLETAGSAWLVVLIAGVNAVLAVALGLFCSAFART
                     EFQAVQFMPVVVAPQLLLCGLFVPRGEMAGWLQAVSDVLPLSYAVEALQEVGAHAEPTG
                     TMWRDLAIVAGAAVAALVLAAATLRRRSG"
     gene            3217..3813
                     /locus_tag="DVH21_RS31210"
                     /old_locus_tag="DVH21_31210"
     CDS             3217..3813
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287561.1"
                     /locus_tag="DVH21_RS31210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31210"
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_114921013.1"
                     /transl_table=11
                     /translation="MNARRTGRRPGTPDTREAILAAAREAFAERGFDAASIRAIAAAAG
                     VDPALVHHYFGGKEELFRAATAFPADPGRLLPAVLAGGPDALGERMVRVFLEVWDSPTG
                     TAAVALLRSAVSNDWTARLLREFLVTQVLRRVLDQLDVDPGQRALRGGLVATQLAGLAM
                     MRYVLRLDAVATAEPATLVAAIGPTVQRYLTGDIT"
     gene            complement(3878..4609)
                     /locus_tag="DVH21_RS31215"
                     /old_locus_tag="DVH21_31215"
     CDS             complement(3878..4609)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785219.1"
                     /locus_tag="DVH21_RS31215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31215"
                     /product="DUF2470 domain-containing protein"
                     /protein_id="WP_114921014.1"
                     /transl_table=11
                     /translation="MRPSPAEIVRTLVAGRLPALVHLARHPGPHQVRHAVDPDGRVLLL
                     VPVVSDLAAALVPPAGDTDVATVLDVLDLPPAAGAPSLGRAWVSGWAERLDGDEERDAA
                     VDFAATDPVGDLLDVGSRFHLHRFEVAEARWERAGRVRRVDPEAYAEAEPDPLHPVEAD
                     LLADLADHHAEQVGDYLRRRLDLPGDQTPQVVRIDRYGLLVAHGRPGATRRARLAFPRP
                     VADVAELSRLLHPMLCPRAAA"
     misc_feature    4624..4644
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    4628..4646
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 32.19"
                     /tool="antismash"
     gene            4677..5285
                     /gene="rpsD"
                     /locus_tag="DVH21_RS31220"
                     /old_locus_tag="DVH21_31220"
     CDS             4677..5285
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012015561.1"
                     /locus_tag="DVH21_RS31220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31220"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_047892216.1"
                     /transl_table=11
                     /translation="MNHPRPKARLSRALGIPLTRKCVRYFERRPYPPGVHGRSRRTTSD
                     YQVRLLEKQRLRHQYNVSEAQLRRLFDEAARGAGKTGETLVALLERRLDAVVLRAGLAR
                     SIYQARQLVAHGHITVDGRKVDRPSYRLRPGQVVGVRERSRALPPFQLAAAGAHADAQP
                     RPYLSAQPAELRATLVREPARHEVPVVCDEQLVVEFYSR"
     gene            complement(5314..7041)
                     /locus_tag="DVH21_RS31225"
                     /old_locus_tag="DVH21_31225"
     CDS             complement(5314..7041)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018824279.1"
                     /locus_tag="DVH21_RS31225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31225"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_123110970.1"
                     /transl_table=11
                     /translation="MRRGLALSPELRTGLAGTLALALVYMVGRVAVPVAVQRGIDHGIV
                     GGLDLNVISLTVAITAGVLVVTTACGYLMMRRLFTVSETALAGVRTRAFRHVHDLSMLH
                     QQSERRGSLVSRVTSDVDQITQFLQWGGVILIVNLGQLLVTTAVMLAYSWQLTLVVLVA
                     FAPAVLVIRQLQRRLAGAYGLVRQRTGTLLGAIGESVVGAPVIRAYGIAGRTARRLDTA
                     IDGQRVAQQRAIRISIMGSSVGELAAGLALAGVVVVGVSLGVDGTLTVGQLTAFLFLVT
                     LFIQPVQIATEVLNEAQNAIAGWRRVLDVLDVSPDVADPGEQGRELPPGPLDARFAGVT
                     FAYPGGPPVLHDVTLDIPAKSRVAVVGETGSGKTTFAKLLTRLMDPTEGQVLLSGVDLR
                     QVRFDSLRSRVVMVPQDGFLFDATVGENVRFARPDLTDERLTAAFAELGLSDWLDGLPS
                     GLDTPVGERGEALSVGERQLVALARAYVADPDLLVLDEATSAVDPATEVRLQRTLDAVT
                     RGRTTLAIAHRLSTAQAADEVIVVDRGRIVQRGPHEELVRDADSVYALLYASWLEQTR"
     gene            complement(7178..9046)
                     /locus_tag="DVH21_RS31230"
                     /old_locus_tag="DVH21_31230"
     CDS             complement(7178..9046)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020215714.1"
                     /locus_tag="DVH21_RS31230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31230"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_205413725.1"
                     /transl_table=11
                     /translation="MASGTSRDVLGRGLRVLGRAIREQPRIFAVAVSGSVLFGLLVIAS
                     AYVVGGVVGDVVVPAVERGEVARGALALAATALFGISVLRVVGIFGRRLGAGYMQYRLQ
                     AAYRRRVTRRYLELPLAWHHRNSTGTLLSNANSDVEAAWYPIAPLPFAVGTLVMLVGAV
                     ASLFFTDWALALVGLAVFPALFALNVVYSRRMAPRQARAQRLRAEVSGIAHESFDGALV
                     VKTMGREAQETVRFASRAGELRDALISVGRLRGVFDPMLETLPSLGTLAVLVVGALRLR
                     EGAITVTELVSVAFLFTVLAFPVRAIGWVLAELPRSVAGWDRVRRVLDATGEMPYGTTT
                     LDPATREPATLAFDDVHFAYEPAEAHLPGAQVLGEVTFTVPAGKTVALVGPTGAGKSTI
                     ASLAVRLVDPGAGRITLDGVDVRELTAASLAATAALVAQVPFVFDDTVRANIALDRAGI
                     GDDEVWAALRLAEADGFVAALPDGLDTMVGERGTSLSGGQRQRLTLARALAGRPRLLVL
                     DDATSAVDPRVEAAILAGLRAPADGGAPASILVVAYRRATIALADEVIYVEQGRVVARG
                     THTELLSTVPGYADLVTAYEQAEQEREQNRTYDEVTPLTSGLEVDR"
     gene            9240..9869
                     /locus_tag="DVH21_RS31235"
                     /old_locus_tag="DVH21_31235"
     CDS             9240..9869
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012183502.1"
                     /locus_tag="DVH21_RS31235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31235"
                     /product="TIGR03085 family metal-binding protein"
                     /protein_id="WP_071098337.1"
                     /transl_table=11
                     /translation="MPRYARAEREALADLMLEVGPDAPTVNEGWTTRDLAAHLLVRERR
                     PDAAGGILLPPLRGYGESVRRRIAAGPYADLIARVRRPPVWSPVSNPLTDELANGMEFF
                     IHHEDVRRARPGWHPRDLPAGQQAVLWKRVALLARMALRRFPAEVLVQAPGYGELRAGG
                     GGERLRLVGAPGELVLFLTGRQRVARVQVDGPADRAERLRTAELGL"
     misc_feature    complement(9925..9936)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            10001..10951
                     /locus_tag="DVH21_RS31240"
                     /old_locus_tag="DVH21_31240"
     CDS             10001..10951
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287567.1"
                     /locus_tag="DVH21_RS31240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31240"
                     /product="terpene synthase"
                     /protein_id="WP_030271952.1"
                     /sec_met_domain="T1TS (E-value: 4.6e-73, bitscore: 245.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDFALSALHEPPFPSRRHPAVDQTAAESAAWVRDFGLVEDQAGR
                     RRLAGAHAAELAARACPEASPSGLRLLTDLINWLFVVDDACDDDGLGATPTLLAPTLAA
                     LLAVLDRHGDPEAPAPADGGPIALALHDLCRRARDRGRPAHLLRLVSQLREYLLALLWE
                     AANRERRRVPGVAEYTQMRRHTGGVRPSFTVTDLARPSAPRADQRVAPALTVLDALATD
                     LICWCNDLFSYGKERGATPEAHNLVTTIAGETGQDESAALYAAADRFNKTLATYAERDA
                     ALSAVADKGMRAFLDTRRDWIRATYDWSRAASRYA"
     misc_feature    complement(11045..11060)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            11090..12916
                     /locus_tag="DVH21_RS31245"
                     /old_locus_tag="DVH21_31245"
     CDS             11090..12916
                     /NRPS_PKS="Domain: AMP-binding (14-471). E-value: 3.6e-88.
                     Score: 287.8. Matches aSDomain:
                     nrpspksdomains_DVH21_RS31245_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475807.1"
                     /locus_tag="DVH21_RS31245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31245"
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="WP_013475807.1"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-86, bitscore:
                     287.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALDVPYRSVPDMFLKRVADSPDRHAFAHPAPDDSGPVWLTWEQV
                     GQRAKAIAAGLHGLGVGLENPVAILANTRLDWVLADFGIMCAGGATTTVYPTTEPEDAV
                     YIIADSGSKVLFAENQAQAAKIAGADLPALTHVVLFDGTPDPAAAVPQLTLAELEERGA
                     AALSAEPDLIDMLVAGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLR
                     VDDLQYLWLPLSHSFGKTLLCGATHVGLPTYVDGRVDKLVELLGVVQPTLMCGAPRVFE
                     KVYNKAVTTAQGAGGAKAKIFAWGVGVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSK
                     LQARLGGRMRVLVSGAAPLSKEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGS
                     VGRAMGDLECRIDTDGEVLLRGKPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGY
                     LRITDRKKDLVKTSGGKYVAPSHIEGMFKAVCPYTSQAVVIGQARNYCTMLVTLDPDAI
                     KGWAAGTPLEGSDYTTIVTSPQAREMVEGYVAELNAKLNRWETIKKVTILPRDLTIEDG
                     EVTPSLKIKRRSVETNFASEIDKMYEGTLAEL"
     aSDomain        11132..12502
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVH21_RS31245_AMP-binding.1"
                     /evalue="3.60E-88"
                     /label="DVH21_RS31245_AMP-binding.1"
                     /locus_tag="DVH21_RS31245"
                     /protein_end="471"
                     /protein_start="14"
                     /score="287.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LKRVADSPDRHAFAHPAPDDSGPVWLTWEQVGQRAKAIAAGLHGL
                     GVGLENPVAILANTRLDWVLADFGIMCAGGATTTVYPTTEPEDAVYIIADSGSKVLFAE
                     NQAQAAKIAGADLPALTHVVLFDGTPDPAAAVPQLTLAELEERGAAALSAEPDLIDMLV
                     AGIGPDHLATLIYTSGTTGRPKGVELLHGGWCWEGVAQAELGLLRVDDLQYLWLPLSHS
                     FGKTLLCGATHVGLPTYVDGRVDKLVELLGVVQPTLMCGAPRVFEKVYNKAVTTAQGAG
                     GAKAKIFAWGVGVGKEKVALEQAGKPVPAGLRMKYALAEKLVFSKLQARLGGRMRVLVS
                     GAAPLSKEIATFFAAANLPISEGYGLTETSAGAFVNPPDGLKIGSVGRAMGDLECRIDT
                     DGEVLLRGKPVMRGYHNLPEETAAAFTEDGFFRTGDIGTLDADGYLRITDRKKDLVKT"
     CDS_motif       11645..11704
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVH21_RS31245_0001"
                     /evalue="2.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="DVH21_RS31245"
                     /protein_end="205"
                     /protein_start="185"
                     /score="23.3"
                     /tool="antismash"
                     /translation="ATLIYTSGTTGRPKGVELLH"
     CDS_motif       12332..12406
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVH21_RS31245_0002"
                     /evalue="1.90E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="DVH21_RS31245"
                     /protein_end="439"
                     /protein_start="414"
                     /score="23.4"
                     /tool="antismash"
                     /translation="GEVLLRGKPVMRGYHNLPEETAAAF"
     gene            complement(12980..14251)
                     /locus_tag="DVH21_RS31250"
                     /old_locus_tag="DVH21_31250"
     CDS             complement(12980..14251)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013475806.1"
                     /locus_tag="DVH21_RS31250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31250"
                     /product="low temperature requirement protein A"
                     /protein_id="WP_114921017.1"
                     /transl_table=11
                     /translation="MRSAAPGSRTTRLELFYDLVFVFAFLNVTTLTASELTPANLYRFL
                     LVLALLWWSWTGFARMGNFFRADQGVLPLVGFVTVAATFLLVLSEPSAFEDLPGGLPGP
                     LVFAGCYFVIRMAQLTVFGWVDRADPVRRRRLLLRAAFPAAATVLLVIAGTVPTRLPQE
                     RFAIPLQLALWTLALLVEYVGGVTLARQWWVVVSAGHWAERHALIVLVALGESIIALGF
                     GPKHGLPLTGPVAVSALLGIVVVAALWWAYFDTLAFALEQALHHARDEATRLRLARDVY
                     TFMHLPMVAGIILYALGLKDLLAEAADPATPTWGLPLGDFWGAILFGGVALHLLSLAGC
                     WWIALREVHRPLLLAVVALAVVGPFVFRIPELIALGVLAVITGAGVAWETRREDGLRRR
                     VRRLALEEQIAAEAEQSRWRRGHL"
     gene            complement(14366..15817)
                     /locus_tag="DVH21_RS31255"
                     /old_locus_tag="DVH21_31255"
     CDS             complement(14366..15817)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (111-461). E-value:
                     4.1e-28. Score: 90.4. Matches aSDomain:
                     nrpspksdomains_DVH21_RS31255_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012014395.1"
                     /locus_tag="DVH21_RS31255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31255"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_013475805.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.5e-26, bitscore:
                     90.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSQVRGVQLARLLGQWHALPGRRRSPDYAALAGAVRGLLADGRL
                     PLGVRLPAERELAEALRISRTTVTAAYRELRESGHLASRRGAGSWTMLPGGHRVASTGL
                     WTPLDDRDMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELREAVARAY
                     TERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALSARRARIAT
                     HGLSDEGWDAELLLGSLRQTRPKLAYVIPEFQNPTGHLMAADLRERLVGTAHAAGTDLV
                     VDESFVDLPLDDTTLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAPQVQRLAA
                     ARVGVDMASPVLDQLVAVHLLTEAPAIVAARRAQLVAQRDALVAALADRLPDWRVRVPS
                     GGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPADELVEAV
                     GRLAAVRYDLDRTSRTQWREPSVIA"
     aSDomain        complement(14435..15484)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVH21_RS31255_Aminotran_1_2.1"
                     /evalue="4.10E-28"
                     /label="DVH21_RS31255_Aminotran_1_2.1"
                     /locus_tag="DVH21_RS31255"
                     /protein_end="461"
                     /protein_start="111"
                     /score="90.4"
                     /tool="antismash"
                     /translation="DMIDLGVAALSAPPQLVPAARAAAEDLPRYLGGAGYHPTGIIELR
                     EAVARAYTERGLPTSPEQIMVTSGTQHALDLVLRLALSPGGAVLVESPTYPNALAALSA
                     RRARIATHGLSDEGWDAELLLGSLRQTRPKLAYVIPEFQNPTGHLMAADLRERLVGTAH
                     AAGTDLVVDESFVDLPLDDTTLPPPVAVFDRHSRVISIGGMSKPYWGGLRIGWVRASAP
                     QVQRLAAARVGVDMASPVLDQLVAVHLLTEAPAIVAARRAQLVAQRDALVAALADRLPD
                     WRVRVPSGGVTLWAELDGPISSALARAAEEVGVRLAPGPRFGLDGTLERFLRLPFTLPA
                     DELVEAVGRL"
     gene            15877..16512
                     /locus_tag="DVH21_RS31260"
                     /old_locus_tag="DVH21_31260"
     CDS             15877..16512
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785228.1"
                     /locus_tag="DVH21_RS31260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31260"
                     /product="membrane protein"
                     /protein_id="WP_013475804.1"
                     /transl_table=11
                     /translation="MAQLGNLRHRPVRRLTQLYAGLVLYGVSMALMIRSELGLDPWDVF
                     HQGLARQTGLSFGTVTIAVGALVLLLWIPLRQRPGLGTVSNVVVIGLVVDATLTVLPPG
                     EGMPARVALLVAGIVANGAATGLYLGAGLGPGPRDGLMTGFVARHPRFSVRLVRTVIEI
                     TVLALGWLLGGTVGLGTVAYALTIGPLAQFFIPVFALPARPAAGAYAT"
     gene            16629..17090
                     /locus_tag="DVH21_RS31265"
                     /old_locus_tag="DVH21_31265"
     CDS             16629..17090
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018804515.1"
                     /locus_tag="DVH21_RS31265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31265"
                     /product="hypothetical protein"
                     /protein_id="WP_013287572.1"
                     /transl_table=11
                     /translation="MGENGWRWSDAWIFVALVIASGAGRHRRAAATRRPEGVRLADVLS
                     TADHLNQAIPERHEVEGAVRRLVGAGLVSVADGWFRVTPDGERLWRTRPSAGLGTTVDT
                     VQGVLTRRHPPAESEWHLDEDDHAAAVQEYVVRSIPMPRRSPEGHSGRQ"
     gene            complement(17099..17866)
                     /gene="hisF"
                     /locus_tag="DVH21_RS31270"
                     /old_locus_tag="DVH21_31270"
     CDS             complement(17099..17866)
                     /EC_number="4.3.2.10"
                     /GO_function="GO:0000107 - imidazoleglycerol-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hisF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019900882.1"
                     /locus_tag="DVH21_RS31270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31270"
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="WP_013287573.1"
                     /transl_table=11
                     /translation="MTVAVRVIPCLDVDAGRVVKGVNFLDLRDAGDPVELAAAYDRAGA
                     DELTFLDVTASSSDRGTMLDVVRRTAESVFIPLTVGGGVRRVADVDTLLRAGADKVGVN
                     TAAIARPELIAEIADRFGRQVLVLSLDVRRAPDGTTPSGFEVTTHGGRRGTGLDAVEWA
                     ARGAELGAGEILLNSMDADGTKAGFDLPLIQAVREVVDVPVIASGGAGEVAHFPPAVGA
                     GADAVLAASVFHFGELTVGEVKDALRGAGHPVR"
     gene            complement(17953..18960)
                     /locus_tag="DVH21_RS31275"
                     /old_locus_tag="DVH21_31275"
     CDS             complement(17953..18960)
                     /NRPS_PKS="Domain: PKS_ER (26-333). E-value: 8.5e-21.
                     Score: 66.3. Matches aSDomain:
                     nrpspksdomains_DVH21_RS31275_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018813683.1"
                     /locus_tag="DVH21_RS31275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31275"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_114921018.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 3e-22, bitscore:
                     77.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEARVNREIHLASRPDGWPTPENFRLVTTEVPTPGPGQVVVRNR
                     FMSVDPYMRGRMNDVKSYVPPFALDAPLDGGAIGEVVAGEAGGVKPGDTVLHGLGWREY
                     ALVDAKGVRKVDPGLAPVTAYLGVLGMTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGS
                     MVGQIAKLRGAGRVIGSAGSAAKVERLTALGFDAAFDYHDGPVYKQLKAAAPDGVDVYF
                     DNVGGDHLEAAIGAMNLHGRAAICGMIAQYNATEPPAAPRNLALVIGKRLTLRGFLVGD
                     HGHLREQFVQQVAGWLREGRLSYDETIVDGIEQAPEAFLGLLRGENLGKMLVRL"
     aSDomain        complement(17962..18882)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVH21_RS31275_PKS_ER.1"
                     /evalue="8.50E-21"
                     /label="DVH21_RS31275_PKS_ER.1"
                     /locus_tag="DVH21_RS31275"
                     /protein_end="333"
                     /protein_start="26"
                     /score="66.3"
                     /tool="antismash"
                     /translation="LVTTEVPTPGPGQVVVRNRFMSVDPYMRGRMNDVKSYVPPFALDA
                     PLDGGAIGEVVAGEAGGVKPGDTVLHGLGWREYALVDAKGVRKVDPGLAPVTAYLGVLG
                     MTGLTAYAGLLDVAAMKPGETVFVSGAAGAVGSMVGQIAKLRGAGRVIGSAGSAAKVER
                     LTALGFDAAFDYHDGPVYKQLKAAAPDGVDVYFDNVGGDHLEAAIGAMNLHGRAAICGM
                     IAQYNATEPPAAPRNLALVIGKRLTLRGFLVGDHGHLREQFVQQVAGWLREGRLSYDET
                     IVDGIEQAPEAFLGLLRGENLGKMLV"
     CDS_motif       complement(18472..18516)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_DVH21_RS31275_0001"
                     /evalue="9.10E-03"
                     /label="PKSI-ER_m5"
                     /locus_tag="DVH21_RS31275"
                     /protein_end="163"
                     /protein_start="148"
                     /score="8.9"
                     /tool="antismash"
                     /translation="GETVFVSGAAGAVGS"
     gene            complement(19013..19438)
                     /locus_tag="DVH21_RS31280"
                     /old_locus_tag="DVH21_31280"
     CDS             complement(19013..19438)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287575.1"
                     /locus_tag="DVH21_RS31280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31280"
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="WP_013287575.1"
                     /transl_table=11
                     /translation="MQVLYTASARATGDGRDGHVRTSDGTVELDLAVPKEMGGAGGAAN
                     PEQLFAAGYAACFHSALRVVARQAKADVSGSVVEAEVGIGPNGSGGYGLAVTLVVDLPA
                     VERAAAEQLVDAAHQVCPYSNATRGNVEVTRTVREAL"
     gene            complement(19440..19886)
                     /locus_tag="DVH21_RS31285"
                     /old_locus_tag="DVH21_31285"
     CDS             complement(19440..19886)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789360.1"
                     /locus_tag="DVH21_RS31285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31285"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_013287576.1"
                     /transl_table=11
                     /translation="MTDDLVLRRQVCFALYAASRALTDVYRPILDEHGLTYPQYLVLLV
                     LWEHDDDAPTVSELGAALRLDSGTLSPLLKRLEAAGLVVRTRSAADERRVEVGLTDRGR
                     ALRERMGDVPRQVASATGLTEAELVFLHGILTRVTETIHRQKEQ"
     gene            complement(19968..20393)
                     /locus_tag="DVH21_RS31290"
                     /old_locus_tag="DVH21_31290"
     CDS             complement(19968..20393)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018785234.1"
                     /locus_tag="DVH21_RS31290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_31290"
                     /product="Rid family hydrolase"
                     /protein_id="WP_013475801.1"
                     /transl_table=11
                     /translation="MTAEPAERPVDAGVVTRLGSGGPWEALYGYSRVVRAGTLAITAGC
                     TSTVDGRVAHAGDAAAQTAQAIRIGLDALAEVGAGPGDVVRTRMYVTDRIYADEVGRAH
                     NAVFGPVRPVATMVVVAGLIDPDLLVEVELEAYLPDR"
ORIGIN
        1 gcccttgacc cagtactcgc cgcggctgcg cgaccagtag gtggcccggc cggtggtgag
       61 cgtgcggtgc agcgcctcgt cgtccatcca ggcgaccatc agcacctcgc ccgagtcgtg
      121 ggcgcggacc acggcggcga ccaggccgtc cggggtgcgg cggagcttgg ccgcgacggc
      181 cgggtcgagc cgggacggac gggccggtcc gggagcgggg gcgccggtca gcggcgcgtc
      241 aggggcgggc acggttgacc attctcccgc acgcggcccg ggcaccgccg acgtgtcccg
      301 ggaggcgggc gtcaccgtcc ccagcgcccg gcccaaccgg ccgaggtagc ggtccacccg
      361 gccgtcgacg agcgcctcgg ccaggtccgc cccgtgggtg gcggcgatct cgtccgcgta
      421 cgggcggatc agcggcagga tgccggtgac cagccgtccg gcggcggcgc cgacctcggc
      481 cgggtcaccg gcgcgcagcc cgaggcagag cagcatgtcg tggcggtagc cgggcggggc
      541 gaccggcagg tccagcgcgg cggtcagggc ggcccgccgg gacaccacgc gcacgctcgg
      601 gttggccggc cgcagcaccg aggggcagag ccgggccagg tcggccgcgg cgagccggac
      661 cccgaccggg tcgtcggcca cacgggccgc ggcgaccttg cccagcgtcg cgatcagctc
      721 ctccaggcgc ggctcgtcgg cgggctggca gagcaccggc aggtcgatcc ggcggcgcca
      781 ttccggtacg gcccacagca gccgggcggg cgcggtgacc gggaggccga acgcccagtc
      841 ggcgggctgg cccagccggc gcacccacga gcggacgtca cgggcggcca ccgacacgtg
      901 cacgaggcga ccggcgaact cggtcaggta cgcccgccgg gccgcgtacg gcgtgccgcg
      961 gcgggacgct gcctgccggg cgcccgtgcc ggcggtccgt ccgtcgtcgg cgaccacgag
     1021 cacgtccacg tccacgtcgc tgtgctcggt ggcggcccgc cgggcatggc tgccgcgcag
     1081 catgatcccg acgaccggcc ggtcggcggc ctgccgcagg cgggcggccc agtcgtcgag
     1141 gaacgcggtg tcgggcaact gcgctggacc cacggcgcca tggtgccgaa atccgatctt
     1201 caccgcaatg accgttgccg gacccactgt ccgccactgg ggcgttcagc ctgattcctc
     1261 ctcggcccgg cggtacgcgt cgatcttgtg ttcgaggacc ttcaggtcct cctccagctc
     1321 ggccatccgg gccagcacgc gggcccggtg cgcctcgaac agcgcccgcc gcgcgccgag
     1381 cgtgctgtcc ccgtgccggg ccagttcggc gtagcggcgc atgtcgcgaa ccggcatccc
     1441 ggtgcgccgc agccgggtga gcaggaacag ccagttgacg tcggactcgg tgtagcgccg
     1501 gcggcccgac gagtcccgcc cgacgcggcc caccaggccc tcctgctcgt accagcgcag
     1561 cgtgtaggtg gtcaggccga cccgttccgc cgcctcaccc acggtgaggc tcatctcccg
     1621 cgtgctgatg tccacgccct ccaggcttcc agttcgagcg cactcgaagt caagtccctc
     1681 attgccaggc gcacgcaatt cacctaccgt tgagttcaac gggtgatgaa ttgatggagg
     1741 cgagcatgga cgacgcggtg tcggtccgcg agctggtggt cgaccggggc gggcggcggg
     1801 tgctgcacgg catcagctgc gaggtgcccc ggggcacggt gaccgggctg ctcgggccca
     1861 gcggcagcgg caagaccacg ctgatgcgcg cggtggtcgg cgtgcagacg gtcggctccg
     1921 gcaccgtcga cgtgctcggc cgcccggccg gctcggccga cctgcgccgc cgggtgggct
     1981 acctgaccca ggccccgagc gtctacgccg acctgacggt gcgggagaac gcccgctact
     2041 tcgcggtgct ccagggccgg ggccgcgccg aggccgaccg cgcggtggcc gacgtaggcc
     2101 tcgccgaggc ggccgaccag ctcgtcggca cgctctccgg cggccagcgc agccgcgcct
     2161 cgctcgcctg cgcgctcgtc ggcgaacccg agctggtgat cctcgacgaa ccgacagtcg
     2221 gccaggaccc ggtgctgcgg gccgacctgt gggcccggtt ccacgccatg gccgcgaacg
     2281 gcaccacgct gctggtctcc agccacgtga tggacgaggc cgcccgctgc gaccggctgc
     2341 tgctgatccg cgagggacgg ctggtcgccg acgacacccc ggccgcggtc cgcgccgcca
     2401 ccgggaccga cgacctggag gaggcgttcc tgcgcctgat ccgcgacgcc gagggagagg
     2461 cgcgatgaac ggacggatcc tggccgccac caccgggcgc atcctgcgcc agctccggca
     2521 cgaccggcgg accgtggcgc tgctcgtggt ggtgccgtcg gtgctgctca cgctcgtcta
     2581 cttcatgtac gtcgaccagc ccgccccgcc cggcgggccc agtacgttcg accgggtggc
     2641 cctgatcatg ctgggcttct tcccgttcat catcatgttc ctggtgacca gcatcgccat
     2701 gctccgcgag cgcaccacgg gcacgctgga gcgtctgctc accacgccgc tgggcaagct
     2761 cgacctgctg ttcggctacg gcatcgcgtt cggcctggcc ggggtgctcc agtccactgt
     2821 ggcctcggtc gtcgcgtacc gggtgttcgg gctggagacc gcgggcagcg cgtggctggt
     2881 cgtgctgatc gccggggtga acgcggtgct cgcggtggcg ctcgggctgt tctgctcggc
     2941 gttcgcccgc accgagttcc aggcggtcca gttcatgccg gtggtggtgg cgccgcaact
     3001 gctgctgtgc ggcctgttcg tgccgcgcgg cgagatggcc ggctggctcc aggcggtcag
     3061 cgacgtgctg ccgctgtcgt acgcggtcga ggcgttgcag gaggtcggcg cgcacgccga
     3121 accgaccggg acgatgtggc gggacctggc gatcgtggcc ggggcggcgg tggcggcgct
     3181 ggtgctggcc gccgcgacgc tgcgccggcg cagcgggtga acgcgcggcg caccgggcgg
     3241 cggcccggca ctccggacac ccgcgaggcc atcctcgccg cggcgcggga ggcgttcgcc
     3301 gaacgcggct tcgacgccgc gtcgatccgg gccatcgccg ccgcggccgg cgtggacccg
     3361 gcgctcgtgc accactactt cggcggcaag gaggagctgt tccgggccgc gacggcgttc
     3421 ccggccgacc cgggacggct gctgccggcg gtgctcgccg gcggcccgga cgcgctcggc
     3481 gagcggatgg tccgggtgtt cctggaggtc tgggactccc ccaccggcac ggcggcggtg
     3541 gcgctgctgc ggtcggcggt gagcaacgac tggaccgcgc gcctgctgcg cgagttcctg
     3601 gtcacgcagg tgctgcgccg ggtgctcgac cagctcgacg tcgacccggg gcagcgcgcg
     3661 ctgcgcggcg ggctggtcgc cacgcagctc gccgggctgg ccatgatgcg gtacgtgctc
     3721 cgcctcgacg cggtcgccac cgccgagccg gcgacgctgg tggcagccat cggcccgacg
     3781 gtccagcgtt acctcaccgg cgacatcacc tgagccggcc cggccgacgg ctccgacggc
     3841 cgggaccgcg ctgctcgggc agccgggccg gcgctgctca ggcggcggcc cgggggcaga
     3901 gcatcgggtg cagcaggcgg gacagctccg ccacgtcggc gacgggccgg gggaaggcca
     3961 gccgggcccg ccgggtcgcg ccgggccgcc cgtgcgcgac cagcagcccg tacctgtcga
     4021 tccggaccac ctgcggcgtc tggtcgccgg gcaggtccag ccgccgccgc aggtagtcgc
     4081 cgacctgctc ggcgtggtgg tcggccaggt cggcgaggag gtcggcctcg accgggtgca
     4141 gcgggtccgg ctcggcctcc gcgtacgcct ccgggtcgac ccggcgcacg cgcccggcgc
     4201 gttcccagcg ggcctcggcc acctcgaagc ggtgcaggtg gaagcggctg cccacgtcga
     4261 gcaggtcgcc gacagggtcg gtggcggcga agtcgactgc cgcgtcgcgc tcctcgtccc
     4321 cgtccagccg ctcggcccag ccggacaccc aggcccggcc gagcgagggc gccccggccg
     4381 ccggcggcag gtcgagcacg tcgagcacgg tggccacgtc ggtgtcgccc gccggcggta
     4441 cgagcgccgc ggcgaggtca ctgaccacgg gtacgagcag cagcacccgc ccgtcggggt
     4501 cgacggcgtg ccggacctgg tgcgggccgg ggtgccgggc caggtggacg agggcgggca
     4561 accggcccgc gacaagggtt cgcacgatct ccgccgggct gggccgcatg atcccgacct
     4621 cctcaacata ggttaggctt acctaataag caggctagac gatcggagac gtcgacgtga
     4681 accacccccg gcccaaggcc cggctctccc gcgccctcgg tatcccgctc acccgcaagt
     4741 gcgtgcggta cttcgagcgg cgcccctatc ccccgggtgt gcacggccgg tcccgccgca
     4801 ccacctccga ctaccaggtg cggctgctgg agaagcagcg gctgcgccac cagtacaacg
     4861 tcagcgaggc ccagctgcgc cgcctcttcg acgaggccgc ccggggcgcc ggcaagaccg
     4921 gcgagacgct cgtcgcgctg ctggagcgac gcctcgacgc ggtcgtgctg cgggccgggc
     4981 tggcacgcag catctaccag gcccgccagc tcgtcgcaca cggccacatc accgtcgacg
     5041 ggcgcaaggt cgaccggccg tcgtaccggc tgcggcccgg ccaggtggtc ggcgtacgcg
     5101 agcgcagccg cgcgctgccg ccgttccagc tcgccgccgc cggcgcgcac gccgacgcgc
     5161 agccccggcc gtacctgtcg gcgcagccgg ccgagctgcg cgccacgctg gtgcgcgaac
     5221 ccgcccggca cgaggtgccg gtggtgtgcg acgagcagct ggtggtggag ttctactccc
     5281 gctgaccgcc gctcccgagc agacccgcca aggtcagcgg gtctgctcca gccaggacgc
     5341 gtacagcagg gcgtacaccg agtcggcgtc gcggaccagt tcctcgtgcg ggccacgctg
     5401 cacgatccgg ccccggtcca ccacgatcac ctcgtccgcc gcctgcgcgg tggacagccg
     5461 gtgcgcgatg gcgagcgtgg tccggccccg ggtcaccgcg tcgagcgtcc gttgcaggcg
     5521 gacctcggtg gccgggtcga cagcgctcgt cgcctcgtcc agcaccagca ggtccgggtc
     5581 cgcgacgtac gcccgggcca gcgccacgag ctgccgctcg ccgacgctca gcgcctcccc
     5641 gcgctcaccg accggtgtgt ccagcccgga cggcaggccg tccagccagt cggagaggcc
     5701 cagctcggcg aaggcggcgg tgagtcgctc gtcggtcagg tcggggcggg cgaagcggac
     5761 gttctccccg accgtggcgt cgaacaggaa gccgtcctgc ggcaccatca ccacccggga
     5821 gcgcagcgag tcgaagcgca cctgccgcag gtcgaccccg gagagcagga cctgcccctc
     5881 ggtggggtcc atcagccggg tgagcagctt ggcgaaggtg gtcttgccgc ttccggtctc
     5941 gcccaccacc gccacccggc tcttggccgg gatgtccagc gtcacgtcgt gcagcaccgg
     6001 gggcccgccc ggataggcga acgtgacacc ggcgaagcgg gcgtccagcg gcccgggtgg
     6061 cagctcccgc ccctgctcgc ccgggtcggc gacgtccggg gagacgtcca gcacgtccag
     6121 cacccggcgc cagccggcga tcgcgttctg cgcctcgttg agcacctcgg tggcgatctg
     6181 caccggctgg atgaacagcg tgaccaggaa caggaacgcg gtgagctggc cgaccgtcag
     6241 cgtgccgtcg acgcccaggc tgaccccgac caccaccacg cccgccagcg ccaggccggc
     6301 ggccagctcc cccaccgagc tgcccatgat gctgatccgg atcgcccgct gctgggccac
     6361 ccgctgcccg tcgatggccg tgtccagccg ccgcgcggtg cgcccggcga tgccgtacgc
     6421 ccggatcacc ggcgcgccca ccacgctctc gccgatcgcg ccgagcagcg tgccggtgcg
     6481 ctgccgcacc agcccgtacg caccggcgag gcggcgctgc aactgccgga tcaccagcac
     6541 cgcgggcgcg aacgcgacga gcaccacgag cgtcagctgc caggagtacg cgagcatcac
     6601 ggcggtggtc accagcaact ggcccaggtt gacgatgagg atcacgccgc cccactggag
     6661 gaactgggtg atctggtcga cgtcgctggt gacccgggag acgagcgacc cgcgccgctc
     6721 ggactgctgg tgcagcatgg acaggtcgtg cacgtgccgg aacgcccggg tgcgcacccc
     6781 ggccagcgcc gtctcgctca ccgtgaacaa ccggcgcatc atcaggtacc cgcaggcggt
     6841 ggtgaccacc agcacgccgg cggtgatcgc cacggtcagc gagatgacgt tcaggtcgag
     6901 gccgccgacg atgccgtggt cgatgccgcg ctgcaccgcc accggcacgg ccacccggcc
     6961 gaccatgtag accagcgcca gcgccagcgt gccggcgagg ccggtgcgca gctccgggga
     7021 gagcgccagc ccgcgccgca gcgtccgcca ggtcgactcg gtggcctcgg tggcctcggt
     7081 ggtctcggtg gtctcggtgg tctcgcccgt ggtcgtactc accgggcccg ccgttcgctc
     7141 gcgactgcgg ggctccgctc cgctgcactc ctcgcgctca ccggtccacc tccaggcccg
     7201 aggtcaacgg cgtgacctcg tcgtacgtcc gattctgctc gcgttcctgc tcggcctgct
     7261 cgtacgcggt gacgaggtcg gcgtagccgg gcacggtgga cagcagctcg gtgtgggtgc
     7321 cgcgggcgac cacccggccc tgctccacgt agatcacctc gtcggcgagc gcgatggtgg
     7381 cccggcggta cgccaccacc aggatcgacg ccggggcgcc gccgtcggcg ggcgcgcgca
     7441 gcccggccag gatggccgcc tcgacccgcg ggtcgacagc gctcgtggcg tcgtcgagca
     7501 ccagcagccg gggtcgcccg gcgagcgccc gggccagcgt cagccgctgg cgctgaccgc
     7561 cggacagcga cgtgccccgc tcgccgacca tggtgtccag cccgtccggc agcgcggcca
     7621 cgaagccgtc cgcctcggcc agccgcagcg ccgcccagac ctcgtcgtcg ccgatgccgg
     7681 cccggtcgag agcgatgttg gcccggaccg tgtcgtcgaa gacgaacggc acctgcgcca
     7741 cgagcgccgc cgtggccgcc agcgaggcgg cggtcagctc ccgcacgtcc acgccgtcca
     7801 gcgtgatccg gccggcgccc gggtccacca ggcgcacggc gagcgacgcg atcgtcgact
     7861 tgcccgcacc ggtggggccg accagggcga ccgtcttccc ggccgggact gtgaacgtca
     7921 cctcgccgag cacctgcgcg ccgggcaggt gcgcctcggc cggctcgtac gcgaagtgca
     7981 cgtcgtcgaa ggcgagcgtg gccggctcgc gggtggccgg gtcgagcgtc gtcgtgccgt
     8041 acggcatctc gccggtcgcg tcgagcaccc ggcggacccg gtcccacccg gcgacgctgc
     8101 gcggcagctc ggccagcacc cagccgatgg cgcgtaccgg gaaggccagc acggtgaaca
     8161 ggaacgcgac gctgaccagc tcggtcacgg tgatcgcgcc ctcccgcagc cgcagcgcgc
     8221 cgaccaccag cacggcgagc gtgccgaggc tgggcagcgt ctccagcatc gggtcgaaca
     8281 cgccacgcag ccggccgacc gagatcagcg cgtcgcgcag ctcaccggcg cgggaggcga
     8341 agcggaccgt ctcctgggcc tcgcggccca tcgtcttgac cacgagcgcg ccgtcgaagc
     8401 tctcgtgcgc gatgccgctg acctcggccc gcagccgctg cgcccgggcc tgccggggcg
     8461 ccatccggcg ggagtagacc acgttgagcg cgaacagcgc cgggaacacg gcgaggccga
     8521 ccagggccag cgcccagtcg gtgaagaaca gcgaggccac cgcgccgacg agcatcacca
     8581 gcgtgccgac cgcgaacggc agcggcgcga tcgggtacca ggccgcctcc acgtcggagt
     8641 tggcgttcga cagcagcgtg ccggtggagt tgcggtggtg ccaggccagc ggcagttcca
     8701 ggtagcggcg ggtgacccgg cggcggtagg cggcctggag ccggtactgc atgtaaccgg
     8761 cgccgagccg gcggccgaag atgccgacga cacgcagcac gctgatgccg aacagcgccg
     8821 tcgcggcgag cgccagcgcc ccgcgggcca cctcgccgcg ctccacggcc ggcacgacga
     8881 cgtcgccgac caccccgccg accacgtacg cgctggcgat caccaggagg ccgaacagca
     8941 cgctgccgct gaccgcgacc gcgaagatcc gtggctgttc ccggatggcc cggccgagca
     9001 cccgtagccc tctgccgagc acgtcccgac ttgtcccgct cgccacgctc tcccccgccg
     9061 taagccgcag ttttctcccc catccttacc gctcgccgcc cgtcccgccg acccggccgg
     9121 gatatgtccg ccgtcacgtt cccgccggag ctgggccgac ggtgaccgga ggcggtccgg
     9181 cggcgtggtc gcgccgggcg tggcgcgccg atcggccggg accggcctac gatcgggcca
     9241 tgccgcggta cgcccgagcg gagcgcgagg cgctcgccga cctgatgctg gaagtgggac
     9301 cggacgcacc gactgtgaac gaggggtgga ccactcgtga cctggcggcg cacctgctgg
     9361 tgcgggagcg ccggccggac gcggcgggcg ggatcctgct gccgccgctg cgcggctacg
     9421 gcgagtcggt ccgtcggcgg atcgccgccg ggccgtacgc cgacctgatc gcccgggtac
     9481 gccgtccccc ggtgtggagc ccggtgagca acccgctcac cgacgagctg gcgaacggga
     9541 tggagttctt catccaccac gaggacgtgc ggcgcgcccg tccgggctgg cacccgcgcg
     9601 acctgccggc cgggcagcag gcggtgctgt ggaagcgggt cgcgctgctg gcccggatgg
     9661 cactgcggcg gttcccggcc gaggtgctgg tgcaggcgcc gggctacggc gagctgcggg
     9721 ccggcggcgg cggcgaacgg ctgcgcctgg tcggtgcgcc gggcgagctc gtcctgttcc
     9781 tcaccggacg gcagcgggtg gcccgggtcc aggtggacgg tccggccgac cgcgccgagc
     9841 gcctgcgcac cgccgagctg ggactctgac cgagggtgtg tagccggtcg ctcgctcact
     9901 gtggaaagtg gacggaccgg cttcgataac ggttacgtcc tcccgtacgc tcctgcgcac
     9961 cggcccgacc ccgcggggcg gcggacaggg gacgacgacg atgcgcgact tcgccctctc
    10021 ggcactgcac gagccaccct ttccctcccg gcgccacccc gccgtcgacc agacggccgc
    10081 ggagagcgcg gcctgggtac gcgacttcgg cctggtggag gaccaggccg ggcgccggcg
    10141 gctggccggg gcgcacgccg cggagctggc cgctcgcgcc tgccccgagg cgtcgccgtc
    10201 cggattgcgc ctgctcaccg acctgatcaa ctggctgttc gtggtggacg acgcctgcga
    10261 cgacgacggg ctcggtgcga cgcccacgct gctggcgccc acgctggccg cgctgctggc
    10321 ggtgctcgac cggcacggcg acccggaggc gcccgcaccg gccgacggcg ggccgatcgc
    10381 cctggcgctg cacgacctgt gccggcgggc ccgcgaccgg ggccggccgg cccacctgct
    10441 gcgcctggtc agccagttgc gggagtacct gctggcgctg ctctgggagg ccgccaaccg
    10501 ggaacgccgg cgggtgccgg gggtggccga gtacacgcag atgcgccgcc acaccggcgg
    10561 ggtgcgcccc agtttcactg tgaccgacct ggcccgcccg tccgcgcccc gcgccgacca
    10621 gcgggtcgcg ccggcgctca ccgtgctgga cgccctcgcc accgacctga tctgctggtg
    10681 caacgacctg ttctcctacg gcaaggagcg gggcgccacc ccggaggcgc acaacctggt
    10741 caccacgatc gcgggcgaga ccgggcagga cgagtcggcg gcgctgtacg cggcggcgga
    10801 ccggttcaac aagaccctcg ccacgtacgc ggagcgggac gcggcgctga gcgccgtggc
    10861 cgataagggg atgcgggcgt tcctggacac ccgccgggac tggatccggg ccacctacga
    10921 ctggtcccgc gcggccagcc ggtacgcctg accggttcca gcaggcggga ccgctgacga
    10981 ctcggccgat cggggctagc cgctggccgg gtgcacgcaa tacccttcgg taaccgcaga
    11041 ccggcgtgac ccccgtcacg tccctccacc cctgaaggcg gctacagcga tggctctcga
    11101 tgtaccgtac cgttccgtac cggacatgtt cctcaagcgt gtggcggact cccccgaccg
    11161 gcacgccttc gcccaccccg cccccgacga ctcgggcccg gtctggctga cgtgggagca
    11221 ggtcgggcag cgcgccaagg cgatcgccgc cgggttgcac gggctcggtg tcggcctgga
    11281 gaacccggtc gcgatcctgg ccaacacgcg cctggactgg gtgctcgccg acttcggcat
    11341 catgtgcgcc ggtggtgcca ccaccaccgt ctaccccacc accgagcccg aggacgcggt
    11401 ctacatcatc gccgactccg gctcgaaggt gctgttcgcg gagaaccagg cccaggcggc
    11461 gaagatcgcc ggggcggacc tgcccgcgct gacccacgtg gtgctcttcg acggcacgcc
    11521 cgacccggcg gcggccgtcc cgcagctcac cctggccgag ctggaggagc ggggcgccgc
    11581 cgcgctgagc gcggagccgg acctgatcga catgctcgtc gccggcatcg gcccggacca
    11641 cctcgcaacg ctgatctaca cctcgggcac caccggccgc ccgaagggcg tggagctgct
    11701 gcacggcggc tggtgctggg agggcgtggc gcaggccgag ctgggcctgc tgcgcgtcga
    11761 cgacctgcaa tacctgtggc tgccgctgtc gcactcgttc ggcaagacgc tgctctgcgg
    11821 cgccacccac gtcggcctgc ccacgtacgt cgacggccgg gtggacaagc tcgtcgaact
    11881 gctcggcgtg gtgcagccga cgctcatgtg cggcgcgccc cgggtcttcg agaaggtcta
    11941 caacaaggct gtcaccaccg cccagggcgc cggcggcgcc aaggccaaga tcttcgcctg
    12001 gggcgtcggg gtcggcaagg agaaggtcgc gctggagcag gccggcaagc cggtcccggc
    12061 cgggctgcgg atgaagtacg cgctggccga gaagctcgtg ttcagcaagc tccaggcccg
    12121 gctcggcggc cggatgcggg tgctggtctc cggcgcggcg ccgctgagca aggagatcgc
    12181 caccttcttc gccgccgcca acctgcccat ctccgagggc tacggcctga ccgagaccag
    12241 cgcgggcgcg ttcgtgaacc cgcccgacgg gctgaagatc ggcagcgtgg gccgggccat
    12301 gggcgacctg gagtgccgga tcgacaccga cggcgaggtc ctgctgcgcg gcaagccggt
    12361 catgcgcggc taccacaacc tgcccgagga gaccgccgcc gcgttcaccg aggacggctt
    12421 cttccgcacc ggtgacatcg gcacgctcga cgccgacggc tacctgcgca tcaccgaccg
    12481 gaagaaggac ctggtcaaga cgtccggcgg caagtacgtc gcgccgtcgc acatcgaggg
    12541 catgttcaag gcggtgtgcc cgtacacctc acaggccgtg gtgatcgggc aggcgcgcaa
    12601 ctactgcacc atgctcgtca cgctcgaccc ggacgcgatc aagggctggg ccgccggcac
    12661 cccgctggag ggcagcgact acaccacgat cgtcacctcg ccgcaggcac gggagatggt
    12721 cgaggggtac gtggccgagc tgaacgccaa gctcaaccgc tgggagacga tcaagaaggt
    12781 gacgatcctc ccccgcgacc tgaccatcga ggacggtgag gtcacgccgt cgctgaagat
    12841 caagcgccgc agcgtggaga cgaacttcgc ctccgagatc gacaagatgt acgagggcac
    12901 gctcgccgag ctgtagcccg taccgccaca cggtcgcgcc ggccgtgccc caccgtcccg
    12961 gggcacggcc gcacgccgtt cacaggtgcc cccgccgcca ccggctctgt tcggcctcgg
    13021 cggcgatctg ctcctccagc gcgagccggc gtacccggcg ccggaggccg tcctcgcggc
    13081 gcgtctccca ggcgacaccg gcgccggtga tcaccgcgag cacgccgagc gcgatcagct
    13141 ccgggatacg gaagacgaac gggccgacca cggccagcgc caccaccgcg agcagcagcg
    13201 gccggtgcac ctcgcgcagc gcgatccacc agcacccggc gaggctgagc aggtgcaacg
    13261 ccaccccgcc gaacaggatc gcgccccaga agtcgcccag cggcagcccc caggtgggcg
    13321 tggccgggtc ggcggcctcg gccagcagat ccttgaggcc gagcgcgtag aggatgatcc
    13381 cggcgaccat cggcaggtgc atgaacgtgt agacgtccct ggccaaccgg agccgggtgg
    13441 cctcgtcccg ggcgtggtgc agcgcctgtt ccagcgcgaa cgcgagcgtg tcgaagtacg
    13501 cccaccacag cgccgcgacg accacgatgc cgagcagcgc cgacaccgcc accggcccgg
    13561 tcagcggcag cccgtgcttc gggccgaagc cgagggcgat gatcgactca ccgagcgcga
    13621 ccagcacgat cagcgcgtgc cgttcggccc agtgcccggc cgagaccacc acccaccact
    13681 gacgggcgag cgtcaccccg ccgacgtact cgacgagcag cgccagcgtc cagagcgcca
    13741 gttgcagcgg gatcgcgaac cgctcctgcg gcagccgcgt cggcacggtt ccggcgatga
    13801 ccagcagcac cgtggcggcg gccgggaacg cggcgcgcag cagcagccgg cggcgccgga
    13861 ccgggtcggc gcggtccacc cagccgaaga cggtgagctg ggccatccgg atcacgaagt
    13921 agcagccggc gaagaccagc gggccgggca gcccgccggg gaggtcctcg aacgcgctgg
    13981 gctcgctgag caccagcagg aacgtcgccg ccaccgtgac gaagccgacc agcggcagca
    14041 caccctggtc ggcgcggaag aagttgccca tccgggcgaa gccggtccac gaccaccaga
    14101 gcagcgccag caccagcagg aagcggtaga ggttggccgg cgtgagctcc gaggcggtga
    14161 gcgtggtgac gttcaggaac gcgaagacga agaccaggtc gtagaagagt tccagccggg
    14221 tggtgcggga acccggggcg gcggaccgca cggtccacga ccgccggact cccctcccgt
    14281 tccccacccg ggcagtctgc gggcaccgga cggcgcggag ccgcacttcg ggccgatcac
    14341 caccggatcg ggcggccggg ccgggtcagg cgatgacgct cggctcccgc cactgcgtgc
    14401 ggctggtgcg gtccaggtcg tagcggaccg ccgcgaggcg cccgaccgcc tccaccagct
    14461 cgtcagcggg cagggtgaag ggcagccgca ggaaacgctc cagcgtcccg tccaggccga
    14521 accgcggtcc gggcgccagc cgtacgccga cctcctcggc cgcgcgggcc agcgcgctgg
    14581 agatcgggcc gtccagctcg gcccagagcg tgacaccgcc gctcggcacg cgtacgcgcc
    14641 agtcgggcag ccggtcggcg agcgccgcga ccagggcgtc ccgctgggcg acgagctggg
    14701 cccggcgggc cgccacgatg gccggcgcct cggtgagcag gtgcacggcg acgagctggt
    14761 cgagcaccgg gctggccatg tccaccccga cccgggccgc ggccagccgc tgcacctggg
    14821 gcgcggaggc gcggacccag ccgatccgca gcccgcccca gtagggcttg ctcatgccgc
    14881 cgatgctgat cacccgggag tgcctgtcga agacggccac cggcggcggc agcgtggtgt
    14941 cgtccagcgg caggtcgacg aaggactcgt cgaccaccag gtcggtgccg gccgcgtggg
    15001 ccgtgccgac cagccgctcg cgcaggtcgg cggccatgag gtggcccgtc gggttctgga
    15061 actcggggat cacgtacgcc agcttcggcc gggtctgccg gaggctgccg agcagaagtt
    15121 cggcgtccca gccctcgtcg gacaggccgt gcgtggcgat ccgggcccgc cgggcggaca
    15181 gcgcggccag cgcgttgggg taggtgggcg actcgacgag cacggcgccg ccgggcgaca
    15241 gggccagccg cagcaccagg tccagcgcgt gctgggtgcc gctggtgacc atgatctgct
    15301 ccgggctggt gggcagaccg cgttcggtgt aggcgcgggc caccgcctcg cgcagctcga
    15361 tgatgccggt cgggtggtag ccggcaccgc cgaggtagcg gggcaggtcc tcggccgcgg
    15421 cccgggcggc ggggacgagc tgcgggggcg cggacagcgc ggccacgccg aggtcgatca
    15481 tgtcgcggtc gtcgagcggc gtccacaggc cggtgctggc cacccggtgc ccgccgggca
    15541 gcatggtcca gctccccgcg ccacggcggc tggccaggtg gccgctctcc cgcagttccc
    15601 ggtacgcggc ggtgacagtg gtccggctga tccgcagcgc ctcggccagc tcccgctcgg
    15661 ccggcaggcg taccccgaga ggcagccgcc cgtcggcgag caagccgcgg acggcgccgg
    15721 cgagcgcggc gtagtcgggg ctgcgccgac ggcccggcag ggcatgccac tggccgagga
    15781 gtcgcgccaa ttggacgccg cgcacctggc tggtcatggc cacacctccg aaattggcac
    15841 ccttgatagc cgcgattggc ccctagggtg gcatgcatgg cacagcttgg caatctccgg
    15901 caccgaccgg tgcggcggct cacccagctc tacgccgggc tggtcctcta cggcgtgagc
    15961 atggcgctga tgatccggtc ggagctgggg ctggacccgt gggacgtgtt ccaccagggg
    16021 ctcgcccggc agaccggcct gtccttcggc accgtcacca tcgccgtcgg cgccctcgtg
    16081 ctgctgctct ggatcccgct gcggcagcgg cccggcctcg gcacggtcag caacgtcgtg
    16141 gtgatcggac tggtcgtcga cgccaccctg accgtgctgc cgcccggaga gggcatgccg
    16201 gcacgcgtcg cgctgctcgt cgccgggatc gtcgccaacg gcgccgccac cggcctctac
    16261 ctcggcgccg ggctcggccc cggcccgcgc gacgggctga tgaccggctt cgtcgcccgc
    16321 cacccccgct tctcggtccg gctggtccgc accgtcatcg agatcaccgt gctggcgctc
    16381 ggctggctgc tcggcggcac cgtcggcctc ggcacggtgg cgtacgcgct caccatcggc
    16441 ccgctggccc agttcttcat cccggtcttc gcgctgcccg cacggccggc ggccggtgcg
    16501 tacgctacgt gaccgcagcc gggccgaccg ccacggcccg gtaccgaccg caacgcgctg
    16561 agctgcgacg acgcacaacc gggaaaccag gtgtttcctc cgccgtcgcg gccgggcatc
    16621 attcctgcat gggggagaac ggatggcgtt ggagcgacgc ctggatcttc gtcgcgcttg
    16681 tcatcgccag tggcgccggc cggcaccggc gggccgccgc gacacgccgc cccgaaggcg
    16741 tacggctggc cgacgtcctc tccacagccg accacctcaa ccaggccatc ccggagcggc
    16801 acgaggtgga gggcgcggtc cggcggctcg tcggcgcggg cctggtcagc gtggccgacg
    16861 gctggttccg ggtcaccccg gacggtgagc ggctctggcg cacccggccc agcgccggtc
    16921 tcggcaccac agtggacacc gtgcagggcg tgctgacccg gcggcacccg cccgccgagt
    16981 ccgagtggca cctcgacgag gacgaccacg ccgccgccgt gcaggagtac gtggtccggt
    17041 cgatcccgat gccgcgccgc tcccccgagg ggcactccgg ccggcagtga ccgccgcctc
    17101 agcgcaccgg gtggcccgcg ccgcgcagcg cgtccttgac ctcgccgact gtgagttcgc
    17161 cgaagtggaa gacgctcgcc gcgagcaccg cgtccgcccc ggcgccgacg gccggcggga
    17221 agtgggccac ctcgcccgcg ccgccgctgg cgatcaccgg cacgtcgacc acctcgcgga
    17281 ccgcctggat cagcggcagg tcgaacccgg ccttggtgcc gtcggcgtcc atcgagttga
    17341 gcaggatctc gcccgcgccc agctcggcgc cgcgcgccgc ccactcgacc gcgtccagcc
    17401 cggtgccccg ccggccgccg tgcgtggtca cctcgaaacc gctcggcgtc gtgccgtccg
    17461 gtgcgcggcg cacgtccagc gagagcacca ggacctgccg gccgaaccgg tcggcgatct
    17521 cggcgatcag ctccggccgg gcgatggccg cggtgttcac gccgaccttg tccgcaccgg
    17581 cgcgcagcaa cgtgtcgacg tcggcgaccc ggcggacacc gccgcccact gtcagcggga
    17641 tgaagaccga ctcggcggtg cgccgcacca cgtcgagcat cgtgccccgg tcgctggacg
    17701 aggcggtgac gtcgaggaag gtcagctcgt ccgcgccggc ccggtcgtac gccgccgcca
    17761 gctccaccgg gtcgccggcg tcacgcaggt cgaggaagtt gacccccttg accacgcgcc
    17821 cggcgtccac gtccagacac gggatgaccc gtaccgccac cgtcatgccc cgagcctaac
    17881 gaacgcgcgg gcggtggtga cccgccggtg aggccggtca ccgccgcccg cggtggagtg
    17941 cgttcgcacc ggtcagagac ggaccagcat cttgccgagg ttctcgccgc gcagcaggcc
    18001 gaggaacgcc tcgggggcct gctcgatgcc gtcgacgatc gtctcgtcgt acgacagccg
    18061 accctcccgc agccagcccg ccacctgctg cacgaactgc tcccgcaggt gaccgtggtc
    18121 accgacgagg aagccacgca gcgtcagccg cttgccgatc accagcgcca ggttgcgtgg
    18181 cgcggcgggc ggctcggtgg cgttgtactg cgcgatcatg ccgcagatgg cggcccggcc
    18241 gtgcaggttc atcgccccga tcgcggcctc caggtgatcg ccgccgacgt tgtcgaagta
    18301 cacgtcgacg ccgtccgggg cggccgcttt gagctgcttg tacaccgggc cgtcgtggta
    18361 gtcgaaggcg gcgtcgaagc cgagcgcggt gagtcgttcc accttcgccg cggaaccagc
    18421 gctgccgatc acccggccgg cgccgcgcag cttcgcgatc tggcccacca tgctgcccac
    18481 cgcgccggcc gcgccggaga cgaacacggt ctcccccggc ttcatcgccg ccacgtcgag
    18541 cagcccggcg tacgcggtca gcccggtcat gccgagcacg cccaggtacg cggtgaccgg
    18601 cgccaggccg gggtcgacct tgcggacgcc cttggcgtcc accagcgcgt actcgcgcca
    18661 gccgagcccg tgcagcaccg tgtcgccggg cttgacgcca ccggcctcgc cggccaccac
    18721 ctcaccgatg gcgccgccgt ccagcggggc gtcgagcgcg aacggcggca cgtacgactt
    18781 gacgtcgttc atccgcccgc gcatgtacgg gtcgacggac atgaaccggt tgcggaccac
    18841 tacctgtccc gggcccggcg tcggcacctc ggtggtgacg agccggaagt tctccggcgt
    18901 cggccagccg tccggccggg acgccagatg gatctcccgg ttgacgcgcg cctcactcat
    18961 cgggcctcct cggttcgcac tgcggggctc cgctgcgctg cactcctcgt gctcacaggg
    19021 cctcgcggac cgtgcgggtc acctcgacgt tcccacgggt cgcgttggag taggggcaga
    19081 cctggtgggc cgcgtcgacg agctgctcgg cggccgcgcg ctcgacagcg ggcaggtcca
    19141 ccacgagcgt cacggccagg ccgtaaccgc cgctgccgtt cgggccgatg cccacctcgg
    19201 cctcgacgac ggagccggag acgtccgcct tggcctgacg ggccaccacg cgcagcgcgg
    19261 agtggaagca ggccgcgtag ccggccgcga agagctgctc cgggttggcc gcgccgccgg
    19321 cgccacccat ctccttcggt acggcgaggt ccagctcgac cgtgccgtcg gaggtccgga
    19381 cgtgaccgtc gcggccgtcg ccggtggcgc gggcggaggc ggtgtagagc acctgcatgt
    19441 cactgctcct tctgtcggtg gatcgtctcg gtgacccggg tgaggatgcc gtggaggaag
    19501 accagctcgg cctcggtgag cccggtggcg gatgccacct gccgcggcac gtcacccatc
    19561 cgctcccgca gcgcccggcc ccggtcggtg agccccacct cgacccggcg ctcatccgcc
    19621 gccgagcggg tacgcaccac cagaccggcc gcctccagcc gcttgagcag cggggagagc
    19681 gtgccggagt cgagccggag cgcagcgccg agctcggaga ccgtgggggc gtcgtcgtcg
    19741 tgctcccaga gcaccagcag caccaggtac tgcgggtagg tcagcccgtg ctcgtcgagg
    19801 atgggccggt agacgtcggt cagggcgcgc gacgccgcgt agagcgcgaa gcacacctgc
    19861 cggcgcagta ccagatcatc ggtcacgccc tgaaccgtag cgcgcaatca agttgtgcac
    19921 aacttatcgg ggcgtggagc ggtgcggcgc cggtcacccg gcaccgctca gcggtccggc
    19981 aggtacgcct ccagctcgac ctcgaccagg agatccgggt cgatcagccc ggccaccacc
    20041 accatcgtgg cgaccgggcg caccgggccg aacaccgcgt tgtgcgcccg gcccacctcg
    20101 tcggcgtaga tccggtccgt cacgtacatc cgggtccgca ccacgtcccc cggcccggcg
    20161 ccgacctcgg ccagcgcgtc caggccgatc cggatcgcct gcgcggtctg cgccgccgcg
    20221 tcgccggcgt gcgcgacccg gccgtccacc gtggacgtgc agccggccgt gatcgccagt
    20281 gtgccggccc ggaccacccg cgagtagccg tagagcgcct cccacgggcc gcccgagccg
    20341 agccgggtca ccaccccggc gtccaccggc ctctcggccg gctcggccgt cacgcgccgg
    20401 cccgcagcgt cgccagcgcc tcggcgacgg tgaacgcgcc cgcgtagagc gccttgccgg
    20461 cgatcacgcc ctccaccccc acgggctcca gcgtggccag cgcccgcagg tcgtccagcg
    20521 tggacacacc accggaggcg atcaccgggg cgtcggtgcg ggcgcacacc tcgcgcagca
    20581 ggtccaggtt cggcccgcgc atggtgccgt ccttggtgat gtcggtgacc acgtaccgcg
    20641 ccgcgcccgc ggcgtccagc cgggccagca cctcgtagag gtcaccgccg tcgcgggtcc
    20701 agccgcgcgc cgacagggta cggccacgca cgtccagccc gatcgccacc cggtcgccgt
    20761 actcgccgca gatccggtcg caccactgcg gatcctccag cgcggcggtg ccgatgttga
    20821 cccgggccgc cccggtgccg agcgccgccc gcagcgactc gtcgtcacgg atgccgccgg
    20881 acagctccac cttcacgtcc agcttgccga ccacctcggc gagcagcgcg gcgttggaac
    20941 cccgcccgaa c
//
