LOCUS       NZ_CP031263            25062 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Micromonospora aurantiaca strain 110B(2018) chromosome, complete
            genome.
ACCESSION   NZ_CP031263
VERSION     NZ_CP031263.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora aurantiaca
  ORGANISM  Micromonospora aurantiaca
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7255264)
  AUTHORS   Wang,R.
  TITLE     Streptomyces kandeliansis sp. nov., an endophytic bacterium isolated
            from mangrove plant
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7255264)
  AUTHORS   Ye,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JUL-2018) Ocean College, Zhejiang University, Zhedalu,
            Zhoushan, Zhejiang 316000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUL-2018
            Assembly Method                   :: ABySS v. 1.5.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003351365.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 12:17:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,622
            CDSs (total)                      :: 6,558
            Genes (coding)                    :: 6,457
            CDSs (with protein)               :: 6,457
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 49 of 101
            Pseudo Genes (incomplete)         :: 65 of 101
            Pseudo Genes (internal stop)      :: 6 of 101
            Pseudo Genes (multiple problems)  :: 18 of 101
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6480667
            Orig. end                         :: 6505729
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031263.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Min Wu.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25062
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="19"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25062
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25062
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15062](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15062
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(15..28)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.83"
                     /tool="antismash"
     gene            754..2187
                     /locus_tag="DVH21_RS29435"
                     /old_locus_tag="DVH21_29435"
     CDS             754..2187
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018791140.1"
                     /locus_tag="DVH21_RS29435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29435"
                     /product="APC family permease"
                     /protein_id="WP_082171407.1"
                     /transl_table=11
                     /translation="MHTRQTAPPPEIGLAQASPDSSRFGYRPELRRSLGFADLLFYGLV
                     FMVPIAPMGIFGSVYSGAGGMVALAYVIGMAALVFTAASYAQMVKAFPLAGSVYNYAGR
                     GIGAPVGFLAGWAILLDYVLVPSLLYLIAAVAMHSTVPAVPVWVWLVGFVLVNTLVNYR
                     GIRMTALITRVMLVGEVIVLVIFLATAGRALAHGKGQGFSWTPLYNPDTFTWALVFGAV
                     SIAVLSFLGFDGISMLAEENKGGAGQIGRAMAAALGVAGLLFIAQTWMAALLLPNPDGL
                     LVNGDPEGTAFYDAARLAGGPWLATLCAVATAVAWGVANSLVAQVATSRLLYAMARDRQ
                     LPKFLAKVSVRHSVPTHAITLTALVSLAIGLYMNWRTDGIALLSSLINFGAMTAFLVLH
                     LAVIWHYLVRQRSRNLIAHLMLPGIGFAILAYVVVNANVAAQRLGFVWLTLGLLVLAGL
                     YAAGRRPELSGLANGREGA"
     gene            2184..3209
                     /locus_tag="DVH21_RS29440"
                     /old_locus_tag="DVH21_29440"
     CDS             2184..3209
                     /GO_function="GO:0016811 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amides
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020217616.1"
                     /locus_tag="DVH21_RS29440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29440"
                     /product="acetamidase/formamidase family protein"
                     /protein_id="WP_030500425.1"
                     /transl_table=11
                     /translation="MTSSVTYQPTEDELRYTFGAHPAVAEIKPGSLLVTSTEDCFGGVV
                     RAVDDLPSKVCQAFNPVTGPFHVLGAEPGDTLALHFAAIAPARDWGMSATFPHFGALTA
                     THTTPMLHPPLEERVWRYTIDTAAGTVTFHARRSGHAIVMPLEPMLGTVGLAPAGGEAR
                     STIVPDAHGGNLDTPEIRPGTTVYLGVNVPGALFAIGDGHARQGQGEVCGVAVETAMNV
                     TVAVDLIKGVATPWPRIETDHRIISIGAARPLEDAYRISQHDLVTWTAQLTGLELLDAY
                     QVVSQAGRAAPGNVCDPLYTMHAAVNKAILAGVNPYEGVHQRLRRIAEAPSEQPGKDHG
                     N"
     gene            3199..4068
                     /locus_tag="DVH21_RS29445"
                     /old_locus_tag="DVH21_29445"
     CDS             3199..4068
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018726147.1"
                     /locus_tag="DVH21_RS29445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29445"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_225319602.1"
                     /transl_table=11
                     /translation="MGTEAMSWAPAEVDLTRPNAARMYDYFLGGSHNFAADRHAADAVL
                     AVAPHVADAARANRAFLRRAVRYALQQGIHQFLDLGSGIPTVGNVHDITRHIDINARVL
                     YVDVEPVAVAHARVLLNNNPRVDVIQADICFPDFILKNSTTQRLIDLTRPVAVLFVSVL
                     HFIPGDVNAIVEPFRAAMPPGSALVISHATSGTATSQTDEVQRLYQRTPTPLQLRAPAE
                     VEALFGDFATVPADGPAAKSASNAALVPVARWRPDPEDQIERGHASASPFLTGFLAGVG
                     MKGAAARE"
     gene            4234..4908
                     /locus_tag="DVH21_RS29450"
                     /old_locus_tag="DVH21_29450"
     CDS             4234..4908
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018792215.1"
                     /locus_tag="DVH21_RS29450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29450"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_030500423.1"
                     /transl_table=11
                     /translation="MSFARLPLRDELFLLGHDDDAGHPHIHRQALALGLAGAVLVDLFL
                     AGRIVLDPNNDRLSGDRWLRLHTDQPLGDLIGDSAIGFIRYGRTAPPVKAFLRGFADDL
                     YERTRAGLVAAGILRQVTRRRLGGLARTDTYLATDTKWAVVARARLRYVAQGREQPDNH
                     TAALAGLVATLGLTGHLYLNDDSTTVTAHLKAIAGQHHRSVRDITAALDAAVGDLATAT
                     YR"
     gene            4936..5589
                     /locus_tag="DVH21_RS29455"
                     /old_locus_tag="DVH21_29455"
     CDS             4936..5589
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013285713.1"
                     /locus_tag="DVH21_RS29455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29455"
                     /product="hypothetical protein"
                     /protein_id="WP_030500422.1"
                     /transl_table=11
                     /translation="MESLVHIRAARWADKDLVALLIADALHPTPLAAWLVPDPGQRCQV
                     LADVVAIWVEHAMFFGDIHLTHDLTAATVGFHRYRPIPPPANYRTRLTDAAGPHADRFD
                     LLDTLLAEKQPTEPHYQLAFLAVRTDAQRGGCGVALLAHHRSRLDRIDLPSWTAVPSGG
                     EHLLARYGYTPRPAITLPDGPTLQPMRRNARHGSSAMPINPARPVDNRWQGFHV"
     gene            6008..6787
                     /locus_tag="DVH21_RS33275"
     CDS             6008..6787
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVH21_RS33275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_143025373.1"
                     /transl_table=11
                     /translation="MAVADTIGRAILARAARIIPSTSTPIPPHLAAVHAHRVLARITVG
                     ATPSDITLTWRATPVLEPGRFEAERAQRVATARTLVLGDPLRARQLLHASLTGIDPATA
                     PADAVHAEAAILLAELQLRLGHPADAITWATYARASTVHLHGLAHRRALHALHVLAAAH
                     SRGGHHQRAYHLYRELTGHLSKSDGPHAQQTLAVQAATALILYALGHCQAARTLLADTI
                     TTHRREHPGHPATAHMTRHLSRIWRECATNGHQHQDA"
     misc_feature    complement(6912..6922)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            7039..8262
                     /gene="fxlM"
                     /locus_tag="DVH21_RS29465"
                     /old_locus_tag="DVH21_29465"
     CDS             7039..8262
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018802441.1"
                     /locus_tag="DVH21_RS29465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29465"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_030500420.1"
                     /sec_met_domain="PCMT (E-value: 1.1e-37, bitscore: 128.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAETSIGESAQLRAALVDTLRDKGMVTSALVEAAIRAVPRHWFMP
                     AGTPTEVAYGYDSSVVTKRDQDGMAISSVSAAYIQARMLELAELRPGMTVLEVGSGGLN
                     AAYLAEVVGPEGRVVSIDIDPEIIDLASTALDATGYSSRVRVLVADAEHGVPDEGPFDA
                     IIVTVGAWDIAPAWLDQLASDGVLVLPLIMNGVTRTIGFRRDGDHLASTSAEVAGFVPM
                     QGAGRHADQVLELADTTGGKVKLAFDSGAPPDLIQLNGVLDADAAEFWSGVTVSHGISF
                     ADLHLWLAWYLDGFGRLAADEGSALAARKRWLPFAVVRGAGLACLVLRDAMQGAGAEFG
                     ARAYGRDGQVAAAALIEQIQAWDRAGRHTPPTFAYWPAGGDRSQIRADATVMNKTHGVV
                     TISWPTSS"
     misc_feature    complement(8376..8386)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            8376..9584
                     /gene="fxlM"
                     /locus_tag="DVH21_RS29470"
                     /old_locus_tag="DVH21_29470"
     CDS             8376..9584
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="DVH21_RS29470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29470"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_030500419.1"
                     /sec_met_domain="PCMT (E-value: 2.5e-43, bitscore: 146.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLQVDDATTLRQAMVGTLRDEGLITTDSVAAAMNAVPRHEFAPG
                     EPLEKVYQTNSTLVPKIDAQGRQTSVVSASHIQAIQLELAEVRPGMNVLEIGSGGYNAA
                     LIAEVVGPTGSVTTMDIDADVVDRARAGLRRAGYEQVNVVLADAEHGVAQHAPYDRIMV
                     TVGAWDIPPAWLDQLTPDGRIVVPLRFAGITRLVAFDRAPGRSVLTASNYRLGSFVPMQ
                     GDGAASEQLIPVTPDVGLRLDQNSTLTFDVPALRKALNTKPVESWSGTPFDMPDELELY
                     LLTSGPELPMIHAAQAAVDQGVVNRTVRNGTPTLVRGGSFAYRIKRENPQTVSGYETGV
                     IAHGPEAEQVGAELLAMIRTWADSYYRRGAAHITYHPNTADTSDLTGWHSTKRHGVLAV
                     AWS"
     misc_feature    8424..8437
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.19"
                     /tool="antismash"
     gene            9665..9829
                     /locus_tag="DVH21_RS29475"
                     /old_locus_tag="DVH21_29475"
     CDS             9665..9829
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018724312.1"
                     /locus_tag="DVH21_RS29475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29475"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_082171406.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 7.9e-16, bitscore:
                     56.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLATVQPDVEGGTLDDFDLDIEFIEAGGTVEHIIKMTEDNCGS
                     TCASACTSC"
     CDS_motif       9665..9769
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAQLATVQPDVEGGTLDDFDLDIEFIEAGGTVEHI"
                     /locus_tag="DVH21_RS29475_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9770..9829
                     /prepeptide="core"
                     /locus_tag="DVH21_RS29475_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-10.50"
                     /molecular_weight="1817.0"
                     /monoisotopic_mass="1815.7"
                     /core_sequence="IKMTEDNCGSTCASACTSC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAQLATVQPDVEGGTLDDFDLDIEFIEAGGTVEHI"
                     /leader_location="[9664:9769](+)"
                     /alternative_weights="1835.1"
                     /alternative_weights="1853.1"
     gene            10001..13012
                     /locus_tag="DVH21_RS29480"
                     /old_locus_tag="DVH21_29480"
     CDS             10001..13012
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.4"
                     /locus_tag="DVH21_RS29480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29480"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_030500418.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.6e-175,
                     bitscore: 582.8, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 5.3e-13,
                     bitscore: 48.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.3e-20, bitscore:
                     71.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYRSVNDALMLRAAVLRPGQIGAWPDLTGSDTATSWRLWLAETLA
                     VPGFAAALAHASPDLAERVTAAISGGPSQSDARRVVLAVMRYLLRTTTRATPYGLFAGV
                     APATASRTGRIHWGTAHRPFARLQASWLAAVLDGLESDVRLRPHVMVRANNLLVERSER
                     LVLEYRAATTDPAGAPTHLRIKTTDMIRTALALAAEPIRWADLTGKLTAECGAPQEGAQ
                     RLVGQMVTQRLLLTSLRPPSTETDPLAHLVDQLETAAAEGGDVGELLDPLRRVRDLKAR
                     HDRAPDEATADARRRDLGRAAAVIQPGQAVGVDLRLDCDLVVPTTVTAEACRAAAALTR
                     LARPTSLRWRDWHTRFLNRYGLHALVPLLDAIDAQVGLGYPDGFTGEPADDSPALTDRD
                     RRLLALAQRAALHREHEVDLDDVLLDRLAGPAPTEIPPTAELTVRVHADSLQAIAGGDF
                     LLSVVRASAQAFSTAGRFLDMFGETDRHRMASCAADSPASAGALLAQLSAVTRYTISLD
                     VNRAPQVLPHLIPVGEYHAPSQAAIGLDDIAVTADAHRLYLVSISRRRALQPVAVNAVE
                     PVRHAHPLARFLAEAPVALATPCSPLEWGPAAKGLPFLPALRYGRTLLSPGRWHLSAAE
                     LPDRHAGWQHWDRALTTWLKATGCPTAVSLGIGDQTLGLDLDKPAHRALLRDHLTRNPT
                     ALLHLIPEGAAWIGGHPHEIVIPLTATTARPPAPRLTSPLVDVRTHGSLPGRDHHYLKI
                     YARPEEQTTILTAHLPRLVVQLPPAGRWWFLRHADPEPHLRLRISGLPIEAITGWTQEL
                     TDADLTQRVQWDTDFGEPGRFGSLAAYQATAAVFAADSAAALAQLAVTTRRPTLGWQAL
                     TAASMVDLVTAVIGDPHDALRWLIARTRAHRPAPPRAVYDQAIRLANPYDPTAVASLTG
                     GENLTDRWARRRRTVAAWRDSLPTVSTMPPAELLPDLLHLHHVRVAGADLDSERACLHL
                     ARAAALSWTTRSIT"
     aSDomain        10451..10723
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_DVH21_RS29480_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.30E-15"
                     /identifier="RREFam001.1"
                     /label="DVH21_RS29480"
                     /locus_tag="DVH21_RS29480"
                     /protein_end="241"
                     /protein_start="150"
                     /score="48.1"
                     /tool="antismash"
                     /translation="VRANNLLVERSERLVLEYRAATTDPAGAPTHLRIKTTDMIRTALA
                     LAAEPIRWADLTGKLTAECGAPQEGAQRLVGQMVTQRLLLTSLRPP"
     gene            13009..14232
                     /locus_tag="DVH21_RS29485"
                     /old_locus_tag="DVH21_29485"
     CDS             13009..14232
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="DVH21_RS29485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29485"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_052165555.1"
                     /sec_met_domain="LANC_like (E-value: 4.9e-36, bitscore:
                     122.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPTTTANPSDVLAAVCARLASPSIVGPSRDGRTRPQSLAGGAV
                     GIALLHIERAVSGHGNEATAHRWIRAAGSEPVSIGRNSDPFHGAPALAFMLHTARPLGG
                     YHRAFASLNDATITLTRQRLVAAHARIDRRDPLTMYEFDLVHGLTGLGLYHLHAHPEHP
                     ISRDVMTYLARITEPLGNGSTQPPWWLPSGLGGTPHPDFPHGHGNIGVAHGISALIALL
                     AYAILHGHDTPAARNALAALCDWTDHHRQDDPAGTWWPGYVTPDTTPRRHRPSWCYGTP
                     GIARAQQLAGLALRDTARQQRAEEAVLAVLRDAAQRARLPEIGLCHGKAGLLQAASRLA
                     AASTDPHRAGQLTAELPGLAAELANQLASQAQGDPELLNGTAGAVLALQTAVTGSPATS
                     WDTFLALA"
     gene            14250..15062
                     /locus_tag="DVH21_RS29490"
                     /old_locus_tag="DVH21_29490"
     CDS             14250..15062
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018829355.1"
                     /locus_tag="DVH21_RS29490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29490"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_030500416.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6.1e-22, bitscore:
                     77.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPPKWRQTTIAFPDPHAADQVATAHLAPILVDAETRQLITTWFY
                     VRKGTWRLRYLPASTTADHYLASQLARLRHDRHISAAVPGIYEPETYAFGGTRAMDTTH
                     HLWHHDSRQLLTPGSNHLAARHPELSIMLAAAMMRAAGLDWYEQGDVWARVANHRDPPQ
                     PTLVNNLLHAVKRLLTADPASLTHQGAPLAATRSWFEAYIAAGDTLNRLNRTGQLQRGL
                     RATLAHHVIFAWNRRSIPGLHQAALATAARNIIFGTNPTAPSAPGGDS"
     gene            15182..16153
                     /locus_tag="DVH21_RS29495"
                     /old_locus_tag="DVH21_29495"
     CDS             15182..16153
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVH21_RS29495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DVH21_29495"
                     /product="hypothetical protein"
                     /protein_id="WP_141722613.1"
                     /transl_table=11
                     /translation="MAAATAVFNLAALLASDCDMPDLAHTWCHRLATAALDHGSDPQHA
                     LEPIVNLARLRIRAGDGPAAWALLETLFQAIDTRTDTLIDGLTIPVARLTEAPGAHTKT
                     RTWLWAVLLGTGAHALASAGRWDDASHRLTQYNGIGARMLDGRQISVIAHATAGRYRQA
                     RAMLDATQPGEPWEDAVTACLLLLMPDSDPADDQANKALTAYHALGPAKPGLTVFHTRL
                     GLTLLDALDNDHPAAEQLGVELIQHAAGDGYAARDLLTHPTCLAAAHHQRVNQLKTLVS
                     TCGLDAGTLSAAQQRALLRALDMAESVIRAPSGALPAVPRGS"
     gene            16473..16997
                     /locus_tag="DVH21_RS29500"
                     /old_locus_tag="DVH21_29500"
     CDS             16473..16997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287267.1"
                     /locus_tag="DVH21_RS29500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29500"
                     /product="hypothetical protein"
                     /protein_id="WP_047894145.1"
                     /transl_table=11
                     /translation="MEIRNIGGRPHTDIAGAAELTGRSEQTVRLKTSPKQRAQGSGWPA
                     SVKQDKKAWLPIDELKHVRDVLLPQIVESSRARVHHVDLNGDPEELISATEFREILTIT
                     QGGWDKYVGMSKAVWDRGEDGYLPMPDREEPAPVQGSTRYWKRRRVQEWINTRSGKVLS
                     ATPPDLPTSDS"
     misc_feature    complement(17321..17330)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     misc_feature    complement(17348..17363)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.93"
                     /tool="antismash"
     gene            17586..18725
                     /locus_tag="DVH21_RS29505"
                     /old_locus_tag="DVH21_29505"
     CDS             17586..18725
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287268.1"
                     /locus_tag="DVH21_RS29505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29505"
                     /product="DUF932 domain-containing protein"
                     /protein_id="WP_030500413.1"
                     /transl_table=11
                     /translation="MSNALDTIPLAARHATLPDLHRILDLQQAHKLDIVAGTAMLRAEA
                     GHLRITGAEPILSESGVTPSDGLYRPTELGDAGLGEKLGIPTSYLRKTRAQALHLYDAN
                     INGWLDLSQGKRYLARCLSDGNGGGILRAFLSDGYKIIDNLDVLMAVLSGIRESGMNVK
                     LDCDLSERRMVVRVHSEAIKTLARNLLRNYRSPFTGATGADNPTVFAGLVFTNSETGSG
                     AFTVTPRIVVQVCDNGLTITKDALRAVHLGAKMDEGTIRWSNDTHQANLNLIGKQTRDA
                     VRRFLDVRYVQRKIEEIEEKAGRRVPDPDHTIRVIAQRLRFTEDEQRLVLNHFIDGGDR
                     TAGGIMHAVTSAAKTLTDPDAAYEMEGVGIRAMEIAATL"
     gene            18926..19462
                     /locus_tag="DVH21_RS29510"
                     /old_locus_tag="DVH21_29510"
     CDS             18926..19462
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013287269.1"
                     /locus_tag="DVH21_RS29510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29510"
                     /product="hypothetical protein"
                     /protein_id="WP_030500412.1"
                     /transl_table=11
                     /translation="MPLFIGLPHGVSLPRNLAEPDARHLVSVLARTYQWTGPLFGRAEV
                     EAYLRAQADDPGSLHDPALNTEEWRRVQNTAAWKNLAATARRAVITADVIGQALRQAGL
                     YCAQCDSPIAGPSTANWGLCPTCLNAADIRDLQTRPCPAGDGVSPHRWNSATCTECTMP
                     APAARPRFTAVATAA"
     gene            19626..21311
                     /locus_tag="DVH21_RS29515"
                     /old_locus_tag="DVH21_29515"
     CDS             19626..21311
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018789010.1"
                     /locus_tag="DVH21_RS29515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_29515"
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="WP_082171427.1"
                     /transl_table=11
                     /translation="MLTITATGAQPSAETDQPIPDGLPDLSTTSTDPAEAADTEHTVAK
                     PALPGGYELLPIKQIKPNPDNVRDDAQALRGIVENLQEDGVRGLLAPVIVTPLDDDTYL
                     IIDGEQRYWSAVEAEQEYIPAIVRDDLAGNREQIISMLRQVHRKDPTAAQVSRGIQQLA
                     LEGMSDEEIARSTGYHPEQVKAGRCVATLDKHTAERTHALGLDFTQAAALAEFTDEPDT
                     IETLLQEAEDAGPFAFARAVEQARSARNAREAEAARRAELTTAGVALLTEHPSYHDAKV
                     KEISDLRDAEGQRITAEDHSDCPGHAVLLYLAYDHRLTERTYCTDWRKHGHTQYSYSTT
                     TRSGPMTEGEKAERRRVIENNKLMEAANTVRREWLTNLLAGKTPPKGTNKLIAEMLADS
                     GYLLSTWVNGGRKMLDDLLSPGKTKRAGTSRVPARVSDARYTVISLAAIAAANESAITR
                     TSWRAPDPAVAKWLQWCITNGFQVGKVEQLIIDGVVNRATNRRTAPAVATNTEPDDPQP
                     ARPEAEPEQAESEGHGVDAATAAAADTAVADTEADPDTGCNLAA"
     gene            22253..22954
                     /locus_tag="DVH21_RS29520"
                     /old_locus_tag="DVH21_29520"
     CDS             22253..22954
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVH21_RS29520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DVH21_29520"
                     /product="hypothetical protein"
                     /protein_id="WP_143025372.1"
                     /transl_table=11
                     /translation="MSTRSPHGRDVVNRVEAAAMLGISVSHLDRLYRERDSNGFPERAA
                     DGRTWHRQDIAKYELPREQATRSARDSVDRSGDPDELVDTATAARILGYRDRSALAGNN
                     PVWLRLQQQVDDESSTPSGRKRRRWKRRTVWEIAENRIGKGGATRTGRPAGTPHGHPDR
                     SGKPDELVGKAEAARVLGYSTANALPSRVLERADEQTAGPKGRYRRKWRRETLWAILDE
                     QGTPPTPDLLS"
     misc_feature    complement(23375..23388)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.57"
                     /tool="antismash"
     misc_feature    complement(23378..23391)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.83"
                     /tool="antismash"
     gene            23450..24976
                     /locus_tag="DVH21_RS29525"
                     /old_locus_tag="DVH21_29525"
     CDS             23450..24976
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="DVH21_RS29525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="DVH21_29525"
                     /product="hypothetical protein"
                     /protein_id="WP_047894141.1"
                     /transl_table=11
                     /translation="MDSHDVGTPPIVEGYGCTTCGVPLTVITTQGGGRTFLHPRSSNDD
                     HEPNPVPLAQLAHVEMTCDFCSAPRPVASFTFAKLEIAMTTAPDVSGMAMHNLGGSWAA
                     CEGCARLVEQRDPEGLTARAVKRARRRGLSDDAQSFFRPLHQALFAATPSTPARQPLPY
                     GANNRSCPPAQDAAPAPEVRSLRPQMLPKVRDRLVRFWRTSGGSYLLRLLDSGETYKIP
                     GHLFPGAPVDAPAAIVDARNPEALRQYTALMANHAENGRVFWIDPDFTALAAHAARDLP
                     DVRVEQVEMPASDGLLVWHTPIYQPVEPHTGLTVPIVAAQWGPIPGGVWITFYTPAETL
                     LQGQQPTELELQGLRERIGWLAPVSSGAGLRFGQPYAPNSEQTRLMLCSLIATWILSTQ
                     PDAEVTEEPADKATRKAYQRANRPAPTVRLVRLRRKQQARQDSPDGTTTRVYTRRWWVA
                     GFFRQQPYGPGRGLRRRTYVRPHIKGPADAPLILTDQVHVLGDARKRHQP"
ORIGIN
        1 atcccccagg ctatgcactc agcgtcattg tcgcagtcgg cagcgtagta gacgacggca
       61 ggcgcagacg agctgaaact aggacaacac tagaacgtcc acgcatcgtc atgggacagg
      121 ccgaacccgc aggctggtcg cacagacaac cacggcgatg gatgggcgct gcgacttcgc
      181 gttacctcca ctgctgtggc agccctcgcg tttgcgagca gcggtgatgg tggaggtgtc
      241 ctcgtggtcg tcgacgtgcg aagcgacagc gtgcgtgacc gcgctcgctg tgccgcttcc
      301 ggccgcggta gtgagtggct ggcgcagccc ggatcgactg tctcgggggt cttcaccctc
      361 gagggtctgc cgcgctggcg cggttgcggc acgtcgctgc agcccgttcg gggtgctcgg
      421 tcagcgggac tacccggggg ccctgcggtt gccagctggg cggccgtgga tgccgaggac
      481 gtcgaacagc tcgttctgga gccggcggcg ccggcaccga atttggtggc ggacgccgcg
      541 cccgaggaac tcggcccatc atccgccgct tgtctgtcgc ccgtactcct cggcggccgt
      601 gcccaggact tgtccatgat ctggcccctc tagcaaccgt ttcagcagct cccggcgatg
      661 cgtctgcctt cgaagccgct gccgccgttg gccagctcga gcactggcgg aagtgagctg
      721 gcgtcgctga ccgacaggaa ggaatggaac agcatgcaca ctaggcagac agcgcctccg
      781 ccggagatcg gcttggcgca ggcgtcgccc gactcctcgc ggttcggata ccgaccggag
      841 ctgcgccgct cactcggctt cgccgacctg ctcttctacg ggctggtgtt catggtgccg
      901 atcgcgccta tgggcatctt cggatccgtc tactccggcg ccggcgggat ggtcgcgctg
      961 gcgtacgtca tcggcatggc ggcgctggtg ttcactgccg cctcatacgc ccagatggtc
     1021 aaggcgtttc cacttgccgg gagcgtgtac aactacgccg ggcgagggat cggcgcaccg
     1081 gtcgggttcc tcgctggctg ggcgatcctg ctggactacg tgctggtgcc gagcctgctg
     1141 tacctgatcg cggcggtggc gatgcactcc accgttccgg cggttccagt gtgggtctgg
     1201 ctggtcggct tcgtgctggt gaacaccctg gtcaactacc ggggaatccg gatgaccgca
     1261 ctgatcaccc gagtgatgct cgtcggcgag gtcatcgtcc tggtgatctt ccttgcaact
     1321 gcgggccgcg ccctcgcgca cggcaaggga cagggcttct cctggacgcc gctctacaac
     1381 cccgacacgt tcacctgggc gctggtgttc ggcgcggtgt cgatcgccgt gctcagcttc
     1441 ctcggcttcg acggcatctc gatgctggcc gaggagaata agggcggcgc ggggcagatc
     1501 ggccgggcca tggccgcggc gttgggtgtg gctggcttgc tgttcatcgc ccagacctgg
     1561 atggccgcgc tgctgctgcc caacccggat ggcctcctcg tcaatggcga tccggaaggc
     1621 accgcgttct acgacgccgc ccggctcgcc ggtggtccct ggctggccac cctgtgcgcg
     1681 gtcgccacgg ccgtcgcctg gggcgtggcg aactccctcg tcgcgcaggt ggccacctcg
     1741 cggctgctgt acgccatggc ccgcgaccgg cagctgccga agttcctggc caaggtgtca
     1801 gtgcgccaca gcgtgcccac tcacgccatc accctcactg cgctggtgtc gctggcgatc
     1861 ggcctctaca tgaactggcg aaccgatggc atcgcgctgc tgtccagcct gatcaacttc
     1921 ggcgcgatga ccgcgttcct cgtgctgcac ctcgccgtca tctggcacta cctggtccgc
     1981 caacgcagcc gcaacctgat cgcgcacctg atgcttccgg gaatcggatt cgccatcctc
     2041 gcctacgtcg ttgtcaacgc caacgtggcc gcccaacgcc tcggcttcgt ctggctcacc
     2101 ctcggcctcc tggtcctggc aggtctgtac gccgccggac gccgccccga gctgtccgga
     2161 cttgccaacg gacgggaggg ggcatgacca gctcggtcac ctaccagcca accgaagacg
     2221 agctgcgtta caccttcggc gcccacccgg cggtcgccga gataaagccg ggcagcctgc
     2281 ttgtcaccag caccgaggat tgcttcggcg gggtcgtgcg cgctgtggac gacctgccgt
     2341 cgaaggtgtg ccaagcattt aatcccgtca ccggcccctt ccacgtgctc ggcgcagaac
     2401 ctggcgacac tctcgcgctg cacttcgcgg ccatcgcccc ggcccgcgac tggggcatgt
     2461 cagccacctt tccgcatttc ggtgcgttga ccgccaccca caccacgccg atgctgcacc
     2521 caccgctcga ggagcgggtg tggcgctaca ccatcgacac cgcggcaggc accgtgacct
     2581 tccacgcccg ccgctccggc catgcgatcg tcatgccctt ggagccgatg ctcggcaccg
     2641 tgggactggc cccggccggc ggggaagcac gctccacgat cgtgcctgat gcgcacggcg
     2701 ggaacctcga cactccggag atccgccccg gcaccaccgt ttacctgggc gtcaacgtcc
     2761 ccggcgcgct gttcgccata ggcgatggcc atgcccgcca gggccagggc gaggtgtgcg
     2821 gcgtcgcggt ggagacagcc atgaacgtca ccgtcgctgt cgacctgatc aagggcgtgg
     2881 ctacaccatg gccacgcatc gagaccgacc accggatcat ctcgatcggc gccgcccgtc
     2941 cgcttgaaga cgcctaccgc atcagccagc acgacctggt tacctggacc gcacaactga
     3001 ccggcctgga gctacttgac gcttaccagg tcgtctcgca ggccggccga gccgcacctg
     3061 gcaacgtctg cgacccgctc tacaccatgc acgccgccgt caacaaggcg atcttggcag
     3121 gcgtgaaccc ctatgaggga gtgcaccagc ggctgcgccg catcgccgag gccccaagcg
     3181 agcaaccggg gaaagaccat gggaactgag gcgatgagct gggcacccgc cgaggtcgac
     3241 ctgactcgtc cgaatgccgc acggatgtac gactacttcc tcggtggcag ccacaacttc
     3301 gccgcggacc gtcacgccgc cgatgccgta ctcgccgtcg caccccatgt cgccgacgcg
     3361 gcccgcgcaa accgcgcgtt cctgcgccgc gccgtccgct acgcactcca gcagggcata
     3421 caccagttcc tcgacctcgg ctcggggata ccgaccgtgg gcaacgtcca cgacatcacc
     3481 cgccacatcg acatcaatgc gcgggttctc tacgtcgatg tcgagccggt agccgtggcg
     3541 cacgccaggg tcctgctgaa taacaacccg cgggtcgatg tcatccaggc cgacatctgc
     3601 tttccggatt tcatcctcaa aaattccacc acgcagcggc tgatcgacct cacccgtccc
     3661 gtcgccgtcc tcttcgtctc ggtcctgcac ttcatccccg gcgacgtcaa cgccatcgtg
     3721 gaaccgttcc gcgccgcgat gccccctggc agcgccctcg tcatctccca cgcgacctcc
     3781 ggcacggcca caagccagac cgatgaggtg cagaggctgt atcagcgcac gcctacccca
     3841 cttcaactgc gcgcccccgc agaggtcgag gcgctgttcg gcgacttcgc cacggtccct
     3901 gccgacgggc cagcagcgaa gtcggcgagc aacgcagcgc tcgtccctgt tgctcggtgg
     3961 cgccctgatc ccgaggacca gatcgagagg ggacacgcgt cagccagccc cttcctcacc
     4021 ggcttcctcg ccggggtcgg gatgaaagga gcagcagctc gtgagtgaac ctcctcggct
     4081 cgctatccgc agggaaccat ccctgcccag tgccagctgg gtactgatgt tcatcggatc
     4141 cgcgggaccc accggcggcg gcaagtgggc gtccgcccag gttgcgcacc agcctgcggc
     4201 agtctgcgtc cagaccacgg aaggggcggg ccgatgagtt ttgctcggct gccgctgcgc
     4261 gacgagttgt tcctgctcgg ccatgacgac gacgccggcc acccgcacat ccaccgccaa
     4321 gccttggcgt tggggctggc cggcgcggtc ctggtcgacc tgtttctcgc cgggcggatc
     4381 gtcctcgacc cgaacaacga ccgtttgtcc ggagaccggt ggctgcgcct gcacaccgat
     4441 caaccgctcg gagacctgat cggggacagt gccatcggct tcatccgcta tgggcgtaca
     4501 gcaccaccgg tgaaggcgtt cctgcgcggc ttcgccgacg acctatacga gcgcacccgc
     4561 gccggactcg tcgccgccgg gatcctccgg caggtcactc gccggcgcct cggcggcctt
     4621 gcccgcaccg acacctacct cgccaccgac accaagtggg cggtcgtcgc ccgcgcacgc
     4681 ctgcggtacg tcgctcaagg ccgtgagcag cccgacaacc acaccgccgc actcgccgga
     4741 ctcgtcgcca ccctcggcct caccggccac ctctacctca acgacgacag tacgaccgtg
     4801 acggcgcacc tgaaggccat cgccggccag caccaccggt cggtgcggga catcaccgcc
     4861 gccctcgacg ccgccgtcgg tgacctcgcc accgcaacgt accggtgaag cgagaccaca
     4921 aggacatcta atccgatgga gagcctggtg cacattcgcg ccgcccgttg ggcagacaag
     4981 gatctggtcg ccctgctgat cgccgacgcc ctgcacccca caccgctcgc cgcgtggctg
     5041 gtgcccgacc cagggcagag gtgccaggtg ctggccgacg tcgtcgcgat ctgggtagaa
     5101 catgcgatgt tcttcggcga catccacctc acccatgacc tcaccgccgc caccgtgggt
     5161 tttcaccgtt accgacccat cccaccaccg gccaactacc ggacccggct caccgacgcc
     5221 gccggaccac acgccgaccg cttcgacctg ctggacacgc tccttgccga gaaacagccc
     5281 accgaaccgc actaccaact ggcgttcctc gccgtccgca ccgacgccca acggggcggc
     5341 tgtggcgtcg cgctgctggc ccaccaccgc agccgcctcg accgcatcga cctgccgtcc
     5401 tggaccgctg ttccctcagg cggggagcac ctgctcgccc gatacggcta cacaccccgg
     5461 ccggcgatca ccttgccgga cggcccgacc ctgcagccga tgcgccgcaa cgctcgccac
     5521 ggcagcagtg ccatgccgat caacccggcc cgcccggtcg acaaccgctg gcaaggcttc
     5581 catgtgtagc cccatcgctc ccgtcactaa cagcctcacc ggtgacatcc acaggcagct
     5641 gaccaccccc gtcctgaaac tggctccgcg aatcatggcc tttccaagca gataccctcc
     5701 agacctgatc gacgccgtcg tccagcgcgt cacggatgcc cgccgagtca gggcatacgg
     5761 cgccgtcacc accgtcgccc atcagatgaa cctcgacccg cgcctagtcc agaaatgggt
     5821 caccaaagcg actgccccag tcgcgctcca gccatgcagg ccggccgccg actcgtgcga
     5881 gatgtacctg ccgccgggac tgctgcactg caggttctgc cagcagccaa tgactcacgc
     5941 cgagtcgcac gactctgggc agggctacca gtgccagcag ggttgcagac cccggcccct
     6001 ggatagcgtg gccgtcgccg acaccatcgg tcgggcgatc ctggcgcgcg ccgctcggat
     6061 catcccgtcg accagcaccc cgatcccgcc acacctcgca gccgtccacg cccaccgcgt
     6121 cctcgcccgc atcaccgtcg gtgccacccc cagcgacatc accctcacct ggcgcgccac
     6181 ccctgttctc gaacccggcc ggttcgaggc cgaacgcgca cagcgtgtcg ccaccgcccg
     6241 caccctggtc ctcggcgacc cgctgcgcgc ccggcaactc ctgcacgcca gcctcaccgg
     6301 catcgacccc gccaccgcgc ccgccgacgc ggtgcacgcg gaagccgcca tcctcctagc
     6361 cgaactgcaa ctccgtctcg gccaccccgc cgacgccata acctgggcca cctacgcccg
     6421 tgccagcaca gtccacctcc acgggctcgc ccaccggcgg gccttgcacg ccctccacgt
     6481 cctcgccgct gcccactcgc gcggcggaca ccatcagcgc gcctaccacc tctaccggga
     6541 actcaccggc cacctctcca aatccgacgg cccgcacgcc cagcaaaccc tcgccgtcca
     6601 agcagccacc gccctcatcc tgtacgccct cggccactgc caagccgccc gcaccctcct
     6661 cgccgacacc atcaccaccc accggcgcga acaccccggc caccccgcca ccgcccacat
     6721 gacccggcac ctgtcccgca tctggcgcga gtgcgccacc aacggccacc agcaccagga
     6781 cgcctgaccg cccgcctcgc cctgatagga ggtccgccgt gaccgcacgc cccctcccca
     6841 gaacaactcg cggtgctaca gcggctcggg cggcgatggg tacgacgaac cactcctgtc
     6901 gttaggcgtc ggtgacatcg caggaaccag cgcagcgctc ccgccggccc cctgtcttcc
     6961 tgcattcgcc gcaccaggcg tgccccgaat gcaggagtgc ctgtccgacc cgatgagaag
     7021 gaagtacgag taacccagat ggctgagaca agcatcggcg agtccgccca gctccgcgcc
     7081 gcgctggtgg acacgctgcg cgataagggg atggtcacga gcgctctcgt tgaggcggcg
     7141 atccgagcgg tgccgcggca ttggttcatg ccggccggta cgccgactga ggtcgcctat
     7201 ggctacgaca gctccgtggt gaccaagcgc gatcaggacg gcatggcgat ctcgtcggtg
     7261 tccgcggcgt acatccaggc gcggatgctg gaactggccg agctgcgacc tggcatgacg
     7321 gtgctggagg tcggctcggg cggattgaac gcggcctacc tcgcagaggt cgtcggtccg
     7381 gagggccgag tagtcagcat tgatatcgac cccgagatca ttgacctggc ctcgaccgcg
     7441 ctggacgcca cgggctacag cagccgagtc cgtgtcctgg tcgccgacgc cgagcacggc
     7501 gtgccggacg aggggccatt cgacgcgatc atcgtgacgg tcggggcgtg ggacatcgcc
     7561 ccggcctggc tcgaccaact ggcctcggac ggcgtgctcg tcctcccgtt gattatgaac
     7621 ggggtcaccc gcaccatcgg gttccggcgc gacggcgacc acctggccag cacgtcggcc
     7681 gaagtggccg ggttcgtgcc gatgcagggc gccggccgcc acgccgacca ggtgctcgag
     7741 ctagccgata ccaccggcgg caaggtcaag ctcgcgttcg actccggcgc acccccggat
     7801 ctgattcagc tcaatggcgt gctggacgcc gacgcggccg aattttggtc tggcgtcacg
     7861 gtcagccacg ggatctcctt cgccgacctg cacctgtggc tcgcgtggta cctggatggg
     7921 ttcggccgcc tcgccgccga cgagggcagc gcactggctg cccggaagcg ctggttgccg
     7981 ttcgcggtcg tacgcggagc cgggctcgcc tgcctcgtgt tgcgggacgc gatgcagggc
     8041 gccggggcgg agttcggtgc ccgcgcctac ggacgcgacg ggcaggtggc cgccgccgcg
     8101 ttgatcgaac agatccaggc gtgggaccga gccgggcggc acacgcctcc gacgttcgcc
     8161 tactggcccg ccggcggcga ccgctcccag attcgcgccg acgccacggt catgaacaag
     8221 acccacggcg tggtgacgat ctcctggccc acgagcagct gactctggcc tcgggccagc
     8281 ctcgctgggt caggttgcaa caacccagcc gcccaaaccc atagggcgaa gcgggacgcc
     8341 aagtccgcca gcccccgcta cccgaaagga ttcccatgac attgcaggtc gacgacgcca
     8401 ccaccttgcg ccaggccatg gtgggcacgc tgcgcgacga aggtctgatc accaccgaca
     8461 gcgtcgccgc agcgatgaac gcggtgcccc ggcacgagtt cgcacccggc gaaccgctgg
     8521 agaaggtgta tcagaccaac agcaccctgg tgcccaagat tgacgctcag gggcgtcaga
     8581 ccagcgtggt ctcggcctcg cacattcagg ccatccagct agaactggcc gaggtacggc
     8641 cgggcatgaa cgtgctggag atcggctcgg gtggctacaa cgccgccctg atcgcggagg
     8701 tcgtcgggcc gaccggttcg gtgacgacca tggacatcga tgccgacgtc gtggaccgtg
     8761 cccgcgcggg tctgcgccgg gccgggtacg agcaggtcaa cgtcgtgctc gccgacgccg
     8821 agcacggcgt ggcacagcac gcgccgtatg accggatcat ggtcacggtc ggggcgtggg
     8881 acatcccgcc cgcctggctc gatcagctca ccccggacgg ccggatcgtc gtgccgctgc
     8941 gcttcgccgg gatcacccgc ctggtcgcct tcgaccgcgc ccccggcagg tcggtgctga
     9001 cggccagcaa ctaccggctc ggctcgttcg tgccgatgca gggcgacggc gccgccagcg
     9061 agcagctgat cccggtcacc cccgacgtcg ggctgcgcct cgaccagaac agcactctca
     9121 cgttcgacgt gccggcgctg cgcaaggcgc tcaacaccaa gcccgtggag agctggtcgg
     9181 gcacgccgtt cgacatgccg gacgagctgg agctgtacct gctgaccagc gggccggaac
     9241 tgccgatgat tcacgccgcg caggccgcgg tcgatcaggg cgtagtcaac cgcacggtac
     9301 gcaacggcac cccgacgctg gtgcgcggcg gcagcttcgc ctatcgcatc aagcgggaga
     9361 atccgcagac cgtcagcggc tacgagaccg gtgtcatcgc ccacgggccg gaagccgagc
     9421 aggtcggtgc cgagctgctc gccatgatcc gcacctgggc ggactcctac taccggcgcg
     9481 gcgctgccca catcacctac cacccgaaca ccgccgacac cagcgatctg accgggtggc
     9541 acagcaccaa gcgacacggc gtcctcgccg tcgcctggtc ctaagagact tcggcgctca
     9601 cctcagcggc ccacgccggg gggagcgtcg gggaacccct atcactgcaa ccagggaggt
     9661 tgtcatggcc cagctcgcca cggtccagcc cgacgtcgag ggcggcaccc tcgacgactt
     9721 cgatctcgac atcgagttca tcgaggccgg cggcaccgtc gagcacatca tcaagatgac
     9781 cgaggacaac tgcggcagca cctgcgcgtc ggcctgcacc agctgctgac cagccgcatc
     9841 cgctggtggc tcgctctgat ggccagccca aaccagatgg gcaggccgta aggcgagcca
     9901 tcgacagcgg atcaggagtg cccggcccgg ggagacctgc tctcgagggt cgggcactcc
     9961 tcacccgcag acagatgatc acgcccatgg ggaggctggt gtgtaccgca gcgtgaacga
    10021 tgccttgatg ctccgggcgg ccgtacttcg cccgggccag atcggcgcat ggcctgacct
    10081 gaccggcagc gacacggcga ccagttggcg cctgtggctt gccgagacgt tggcggttcc
    10141 ggggttcgcg gcagccttgg cccacgcgtc accggacctc gccgagcggg tcaccgccgc
    10201 catcagcggc ggcccgtcgc aatctgacgc ccgccgggtg gtgctcgcgg tcatgcgcta
    10261 cctgctgcgc actaccaccc gtgccacacc atacgggttg ttcgcgggcg ttgcccccgc
    10321 caccgcgagc cgcaccggcc gcatccactg gggcactgca caccggcctt tcgctcgcct
    10381 tcaggcatcc tggctggccg ccgtcctcga tggcctggaa tccgacgtgc ggctgcgccc
    10441 gcatgtgatg gtgcgcgcca acaacctgct ggtcgagcgc agtgagaggc tggtgctgga
    10501 gtaccgcgcc gccacgaccg accccgcagg tgcgcccacg catctgcgca tcaagaccac
    10561 cgacatgatc cgcacggctc tcgcgctggc ggctgagccg atccggtggg ccgacctcac
    10621 cggcaagctg acggccgaat gtggggcgcc gcaggaaggc gcgcagcggc tggtcggcca
    10681 aatggtgacg cagcggttgc tgttgaccag cctgcgcccg ccgtcgaccg agaccgaccc
    10741 cctggcgcat ctcgtggatc agctggagac cgccgcagcc gaaggcggcg acgtaggcga
    10801 gctacttgat ccgctgcgtc gcgttcgcga tctcaaagcc cgacacgacc gcgcaccgga
    10861 cgaggccacg gctgatgccc gccgccggga cctcggcaga gccgccgccg tgatccagcc
    10921 cgggcaggcg gtcggtgtcg atttgcggct ggactgcgac ctcgtggtgc cgacgacggt
    10981 gacggccgag gcatgccgcg ccgctgccgc gctgacccgc ctcgcccggc cgacatcgct
    11041 tcggtggcgg gactggcata cgcgtttctt gaaccggtac ggcctgcacg ccctcgtccc
    11101 gctcctggat gcgatcgatg cccaggtggg cctcggctat ccggacggct tcaccggcga
    11161 gccggccgat gattcgcccg cgttgaccga cagggaccgg aggctactcg ccttggcgca
    11221 acgtgccgcc ctgcaccgtg aacacgaggt cgacctcgac gacgtcctcc tggacaggct
    11281 ggccggcccg gcgccgaccg agatcccgcc gaccgccgag ctcaccgtgc gcgtccacgc
    11341 cgactccctc caagccatcg ccggcggcga cttcctgctg tcggtcgtac gtgcttcagc
    11401 gcaagccttc tccaccgcgg gccggttcct agacatgttc ggcgagaccg accggcaccg
    11461 gatggcctcc tgcgccgccg acagcccagc cagcgccggc gcgttgctgg cccagctgtc
    11521 cgcggtcacc cgctacacca tcagcctgga cgtcaaccgc gccccccagg tgctgccgca
    11581 tctgatcccc gtcggcgagt accacgcccc gtcgcaggcc gcgatcggct tggacgacat
    11641 cgcggtaacc gccgacgcgc accgcctgta cctggtgtcg atctctcgcc gacgggcgct
    11701 gcagccggtc gcagtcaacg cggtcgagcc cgtacgacac gcccaccctc tggcccgctt
    11761 cctggccgaa gcgcccgtgg ccctcgctac cccgtgctca ccgctggagt gggggccagc
    11821 ggccaagggc ttgccgttcc tgcccgcgct gcggtacggc cggaccctct tgagccccgg
    11881 gcggtggcac ctgagcgccg ccgaactgcc cgaccggcat gccggctggc agcactggga
    11941 ccgcgcgctg accacctggc tcaaggccac aggctgccct accgccgtct cgcttggtat
    12001 cggcgaccag accctcggcc tcgacctgga caagcccgct caccgggcgc tgctacgcga
    12061 ccacctgacc cgcaacccca ccgcactgct gcatctcatc cccgaaggcg ccgcctggat
    12121 cggcgggcat ccccacgaaa tcgtcatccc gttgaccgcc accaccgcga gaccaccagc
    12181 gccccgcctc accagccccc tggtcgatgt ccgtacccac ggcagcttgc ctggccgcga
    12241 ccaccactac ctgaagatct acgcccggcc ggaagaacag accaccatcc ttaccgccca
    12301 cctgcctcgg cttgtcgtgc aactcccgcc ggcgggcagg tggtggttcc tgcgccacgc
    12361 cgacccggag ccgcacctgc ggctgcgtat cagcggcttg cccatcgaag ccatcaccgg
    12421 ctggacgcag gagctgaccg acgccgacct gacccagcga gtccagtggg acaccgactt
    12481 cggcgagcct ggccgcttcg gcagcctggc cgcgtaccag gcaacggcag ccgtgttcgc
    12541 ggcggactcc gcagccgcgc tcgcccaact ggccgtcacc acgcgacgtc ccaccctggg
    12601 ctggcaggcg ttgaccgccg cgagcatggt cgacctcgtc acggcggtca tcggcgaccc
    12661 acacgacgcc ctgcgatggc tgatagcccg tacccgcgcg caccggccag cacccccacg
    12721 agccgtctac gaccaggcca tccgcctggc caacccgtac gaccccaccg ccgtggcgtc
    12781 cctgaccggc ggcgagaacc tgacggaccg ctgggctcgg cgccgccgca ccgtggccgc
    12841 ctggcgcgac agcctgccca ccgtcagcac catgccgccg gccgagctgc tgcccgacct
    12901 gctgcacctg caccacgtcc gcgtcgccgg ggccgacctc gacagcgaac gagcctgcct
    12961 gcacctcgcc cgcgccgccg cgctgagctg gacgacaagg agcatcacgt gaccaccccg
    13021 accaccaccg ccaacccctc ggatgtgctc gcggcggtct gcgccagact cgccagcccc
    13081 tccatcgtcg gcccgtcacg cgacgggcgg acccggccgc aatcgctggc cggaggcgcg
    13141 gtgggcatcg ccctgctgca catcgagcgg gccgtctccg gacacggcaa cgaagccacc
    13201 gcccaccgct ggatacgcgc cgccggcagc gagccggtca gcatcggccg caactccgac
    13261 cccttccacg gcgcccccgc gctggcgttc atgctgcaca ccgcccgccc cctcggcggc
    13321 taccaccgcg ccttcgccag cctcaacgac gccacgatca ccctcaccag acaacggctc
    13381 gtcgccgcac acgcccgcat agaccgccgc gacccgctga cgatgtacga gttcgacctc
    13441 gtccacggcc tgaccgggct cgggctctac cacctgcacg cccaccccga gcaccccatc
    13501 agccgcgacg tgatgaccta cctggcccgc atcaccgaac ccctcggcaa cggctccacg
    13561 cagccgccgt ggtggctgcc atcggggctc ggcggcacac cacacccaga ctttccccac
    13621 gggcacggca acatcggcgt agcccacggc atcagcgccc tcatcgccct gctcgcctac
    13681 gccatcctcc acggccacga cacccccgca gcccgcaacg ccctcgccgc tctatgcgac
    13741 tggaccgacc accaccgcca agacgacccg gccggaacat ggtggcccgg ctacgtcacc
    13801 cccgacacca ccccacggcg gcaccggccc tcctggtgct acggcacccc cggcatcgcc
    13861 cgcgctcagc aactcgccgg gctcgccctg cgagatacgg cccgccagca acgggcagaa
    13921 gaggctgtgc tcgccgtgct gcgagacgcc gcccaacgcg cccggctgcc cgagatcggc
    13981 ctctgccacg gcaaagccgg cctcctgcag gctgccagcc gcttggccgc cgccagcacc
    14041 gacccgcacc gcgcgggtca gctcaccgcc gagctgcccg gcctggcggc cgaactcgcc
    14101 aaccagctcg ccagccaagc ccaaggtgat ccagagctgc tgaacggcac ggccggtgcc
    14161 gtgctggcgc tgcagaccgc cgtcaccggc agcccggcga ccagctggga caccttcctc
    14221 gccctcgcct gaacccaagg gaaacgaaca tgacgccacc caaatggcgg cagaccacca
    14281 tcgccttccc cgacccccac gccgcagacc aagtagccac cgcccatctc gcgccgatcc
    14341 tcgtcgacgc cgaaacccgc cagctcatca ccacctggtt ctacgtccgg aaaggcactt
    14401 ggcggctgcg ctaccttccc gcctccacca ccgccgacca ctacttggcc agccagctgg
    14461 cccgcctacg ccacgaccgc catatcagcg ccgccgttcc gggaatctac gagcccgaga
    14521 cctacgcctt cggcggcacc agagccatgg acaccaccca ccatctgtgg catcacgaca
    14581 gccgccagct actcaccccc ggctccaacc acctagccgc gcggcacccc gagctgtcga
    14641 tcatgctcgc cgcggccatg atgcgagccg caggccttga ctggtacgaa caaggcgacg
    14701 tctgggcccg cgtcgccaac caccgagacc caccccagcc cacgctcgtc aacaacctgc
    14761 tgcacgcggt gaaacggctc ctcactgccg atccagccag cctcacccac cagggggcgc
    14821 cgctggccgc cactcgcagc tggttcgagg cttacatcgc cgccggcgac actctcaacc
    14881 ggctcaaccg gacaggacag ttgcagcgcg gcctccgcgc aaccctcgcc caccacgtga
    14941 tcttcgcctg gaaccggcgc agcattcctg gcctgcacca agcggcactc gccaccgccg
    15001 ccagaaacat catcttcggc accaacccca ccgcgccctc ggccccgggc ggtgactcat
    15061 gaaccccgca atagcccgta gattcccgct gatcgcccgg ccccgccccg tatgcacacc
    15121 cctgccccag cgcatcgccg acctcgagga acgcgccgac ctcgcctacc acagcggtga
    15181 cgtggccgcc gcgaccgcgg tcttcaacct cgccgcgctc ctagcctcgg actgtgacat
    15241 gcccgacctg gcccacacct ggtgccaccg gctcgccacc gcggcactcg accacggcag
    15301 cgatccccag cacgcactcg aaccgatcgt gaacctcgcc cgcctccgca tccgcgcggg
    15361 cgacggcccc gccgcctggg ccctgttgga aaccctgttc caggccatcg acacccgcac
    15421 cgacaccctg atcgacggcc tcaccatccc cgtcgcccgc ctcaccgagg cacccggtgc
    15481 ccacaccaag acacgaacct ggctatgggc cgtcctgctc ggcaccggcg cccacgccct
    15541 cgccagcgcc ggacggtggg acgacgccag ccaccgcctc acccaataca acggcatcgg
    15601 cgcacgcatg ctcgacggca ggcagatcag cgtcatagcc catgccacag caggccgcta
    15661 ccgccaggca cgcgcgatgc tagacgccac ccaaccgggc gaaccatggg aagacgccgt
    15721 cactgcctgc ctgctcctgc tgatgccaga ctccgatccc gcagacgacc aggcgaacaa
    15781 ggcgctgacc gcctaccacg ccctcggacc cgccaagccc ggactcaccg tcttccacac
    15841 ccggcttggc ctcacccttc tagacgccct cgataacgat cacccagccg ccgagcagct
    15901 cggcgtcgaa ctgatccaac acgctgctgg cgacgggtac gccgcacgcg atctactgac
    15961 tcatcccact tgcctcgccg ccgcccacca tcaacgggtc aatcagctca agacgctcgt
    16021 atcaacatgc ggcttggacg caggcaccct gtcggcggcg cagcaaagag ccctgctccg
    16081 cgcgctcgac atggccgaat cggtaatccg tgccccttcg ggcgctctac cagccgtccc
    16141 gcggggcagc tgaacggcgt ccgtcctctc tgggcgcaca gcgctgctcc tggccgcagc
    16201 cggtggcgct ctttgccgat cgtctttgcc gggcttcgtc agggggagca cggctctcaa
    16261 gtacggcatc aacccgccga tctcccaggc gaccgagagc caggctgcta ccatctgcac
    16321 cgcttcggcc acacgtccgc cgcttagcgg tggacttgtg ggtggggctg ttggttggat
    16381 cacgcggccg gggggttgcc gcttcgttcg ttcgcggacg atgttccccc ggccgttcca
    16441 accgctggcc accgatgcag gcaggggtag gcatggaaat ccggaacatt ggtggccggc
    16501 cacacacgga catagccggc gcagccgagc tgaccggacg gtccgaacag acggtgcggc
    16561 tcaagacgtc accgaagcag cgcgcccaag ggtcaggctg gcccgcgtcg gtcaagcagg
    16621 acaagaaggc gtggcttccc atcgacgagc tgaagcacgt ccgggatgtc ctcctaccgc
    16681 agatcgtgga atcctcccga gcgcgggtcc atcatgtcga cctcaacggc gaccccgagg
    16741 agctcatctc cgccaccgag ttccgggaga ttctcaccat cacgcagggc gggtgggaca
    16801 agtacgtcgg aatgagcaag gccgtgtggg accgcggcga ggacggctac cttcccatgc
    16861 ctgaccgcga agaacccgca ccagtacagg gatctactcg ttactggaaa cgcagacgcg
    16921 tgcaggaatg gatcaacacc cggagcggga aggtgctcag cgccacgccg cccgatttgc
    16981 caaccagtga ctcctaatgc agccgctgcc tgaagcgaat ttgccgtaag gcaagacgac
    17041 tgcttccgga tgtagaccca ttcgcaccac tcgacgcccg ctagcccgcc cggtccgaca
    17101 gccgtctcgc cgcttgggct gaatcgacct tcggtcgatg gcctccagcc gggtcagcgt
    17161 cccgccgctg aaccgcggcg cctcgccggc gaggcaggct ccgggaaggg ggaggcagcg
    17221 ccgatccttc ccggcgacct gaccccacag tgccaaccat gtttggctgt gggggtcaag
    17281 ccacacccca ggcttgaccc ccacagccaa acatggtcga tcaaagatca ggccaccggg
    17341 aaggctctct gacgcacatc acataaccgg ctgcgccgac caattcacca atcagcacgt
    17401 agagaaacgt tagtagatca tgcgttatta attaccgacg gttacacatt ggccacgctg
    17461 gaatttcacg aattgaacgg tctcaagtgg actctgcggg gctggtcatg tatcattaaa
    17521 tacatgaggg aggggacggc aacccccgcc ctcgcagcca acaccccaac cgaaagggat
    17581 caacggtgag caacgcgctc gacaccatcc ccctggccgc ccggcacgcg acgctgccgg
    17641 acctgcaccg catcctcgac ctccagcagg cgcacaagct cgacatcgtc gctggcacgg
    17701 cgatgctgcg agccgaggcc ggacacctgc gcatcaccgg cgcggaaccc atcctcagcg
    17761 aatcgggtgt caccccctcc gacgggctct accggcccac cgaactgggc gacgcgggac
    17821 tcggcgaaaa gctcggcatc cccaccagct acctgcgcaa gacccgcgcg caggcactgc
    17881 acctctacga cgccaacatc aacggctggc tcgacctcag ccagggcaag cgctatctcg
    17941 cccgctgcct gtccgacggc aacggtggcg gcatcctgcg cgccttcctt agcgacggat
    18001 acaagatcat cgacaacctc gacgtgctga tggccgtcct gtccggcatc cgcgagtcgg
    18061 gcatgaacgt caaattggat tgcgacctaa gcgagcgccg gatggtcgtc cgcgtgcact
    18121 ccgaggccat caagaccctc gcccgcaacc tgctgcgcaa ctaccgcagc cccttcaccg
    18181 gagccaccgg cgcggacaac ccgaccgtct tcgccggtct cgtcttcacg aacagcgaga
    18241 caggctctgg cgcgttcacc gtcactcccc gcatcgtcgt acaggtctgc gacaacggcc
    18301 tcaccatcac caaagacgcc ctgcgagcag tgcacctcgg cgcgaagatg gacgagggca
    18361 ccatccgctg gagcaacgac acccaccagg cgaacctcaa cctgatcggc aagcagaccc
    18421 gcgacgcggt gcgccgcttc ctcgacgtcc gctacgtgca gcgcaagatc gaagagatcg
    18481 aggagaaggc cggccgccgc gtccccgacc ccgaccacac catccgggtc atcgcccagc
    18541 ggctgcggtt caccgaggac gagcagcggc tcgtcctgaa ccacttcatc gacggcggcg
    18601 accgcacggc cggaggcatc atgcacgccg tcaccagcgc cgcaaagacc ctcaccgacc
    18661 ccgacgccgc gtacgagatg gagggcgtcg gcatccgggc gatggaaatc gcagccacgc
    18721 tctgacccga gctccgggtg ccgctggcgc aacccgccag cggcacccgg acccagcgcc
    18781 cagccgcacg gctgaccgcg tcgacgcgca tcgagcacgc cgacgcgggc taccgctccc
    18841 gcaccgcacg gccacagcca tcgggccttc aacccgcccg cagccgtgcg ctgcaaaccc
    18901 accgctgcgc accttgggag aagccatgcc cctgttcatc gggttgcccc acggcgtgtc
    18961 cctgccccgc aaccttgccg agcccgacgc ccgacacctc gtctccgtgc tcgcccgcac
    19021 ctaccaatgg accggaccgc tgttcggccg ggcagaagtc gaggcgtacc tacgcgccca
    19081 ggccgacgac cccggcagcc tccacgaccc agccctgaac accgaggagt ggcgccgcgt
    19141 ccagaacacc gccgcatgga agaacctcgc ggcaacagcc cgccgtgcag tcatcaccgc
    19201 cgacgtgatc ggccaggcac tgcgccaagc cggcttgtac tgcgcccaat gtgactcccc
    19261 catcgccggt ccctcgaccg ccaattgggg gctctgcccc acctgcctca acgccgccga
    19321 catccgcgac ctgcaaaccc gcccctgccc agccggcgac ggcgtaagcc ctcaccgctg
    19381 gaacagcgcc acctgcaccg aatgcacgat gcccgcacca gccgcccgcc cccgcttcac
    19441 cgccgtcgcc acagccgcct aacagccgtg cgacgttcct cctttcagtg gcaacttcgc
    19501 agcgacccga cacggatccg ccagcgccgc tgaacgcagc ggcctcgaaa ccaccggtca
    19561 ggcccggacg gcaacccggg cctgaccggc caaccaacaa acccacaacc gaagggagca
    19621 caccggtgct cacgatcacc gcaaccggcg cgcagcccag cgcggagacc gaccagccca
    19681 tcccggacgg gctgcccgac ctgtcgacca cctccaccga cccggcggag gcagccgaca
    19741 ccgagcacac cgtcgccaag cccgccctgc ccggcggcta cgaactgctg cccatcaagc
    19801 agatcaagcc caaccccgac aacgttcgcg acgacgccca agccctgcgc ggcatcgtgg
    19861 agaacctgca agaggacggc gttcgcgggc tgctcgcccc ggtcatcgtc acgccgcttg
    19921 acgacgacac gtacctgatc atcgacggcg agcagcgata ctggtccgcc gtcgaagccg
    19981 agcaggagta catcccggcc atcgtccggg acgacctggc cggcaaccgc gagcagatca
    20041 tcagcatgtt gcggcaagtc caccgcaagg accccaccgc cgcacaggtg tcccgaggca
    20101 tccagcagct cgcacttgag ggcatgagcg acgaggagat cgcccgcagc accggctacc
    20161 accccgaaca ggtcaaggcc ggccgctgcg tcgccaccct ggacaagcac accgccgagc
    20221 gcacccacgc actcggactg gatttcaccc aggctgccgc cctcgccgag ttcaccgacg
    20281 aacccgacac catcgaaacg ctgttgcagg aagccgaaga cgccggaccg ttcgcgttcg
    20341 cccgagcagt cgaacaggcc cgctccgccc gtaacgcccg cgaagccgaa gccgcacgcc
    20401 gcgccgagct gaccaccgcc ggggtggccc tgctgaccga acaccccagc taccacgacg
    20461 cgaaggtcaa ggagatcagc gacctccgcg acgccgaagg ccagcgcatc accgccgagg
    20521 accacagcga ctgccccggc cacgccgtcc tgctgtacct ggcctacgac caccgcctca
    20581 ccgagcgcac ctactgcacc gactggcgca agcacggaca cacccagtac agctacagca
    20641 ccaccactcg cagcggcccc atgaccgagg gagaaaaggc cgagcggcgg cgcgtcatcg
    20701 agaacaacaa actgatggaa gccgcgaaca ccgtccgccg tgagtggctg accaacctgc
    20761 tcgctggcaa gaccccaccc aagggcacca acaagctcat cgcggagatg ctggccgact
    20821 ccggctacct cctgtccacc tgggtcaacg gcggccggaa gatgctggac gacctcctct
    20881 cgcctggcaa gaccaagcgc gccggcacca gccgcgtccc ggcccgcgtc agcgacgccc
    20941 gctacacggt catctccctg gccgccatcg ccgccgcgaa cgaaagcgcc atcacccgca
    21001 cctcctggcg tgccccggac ccggccgtcg cgaagtggtt gcagtggtgc atcaccaacg
    21061 gcttccaggt cggcaaggtc gaacagctca tcatcgacgg cgtcgtcaac cgcgccacga
    21121 accggcgaac ggcccccgcc gtagccacga acacggagcc agacgacccg cagcctgccc
    21181 gccccgaggc cgaacccgag caggcagaga gcgagggcca cggcgttgac gcggcaaccg
    21241 ccgctgctgc tgacaccgca gttgccgaca cggaggcgga ccccgacacc gggtgcaacc
    21301 tcgccgccta gccgctgccg gtcgggggcc acaaccggct cccgaccggc accacccaag
    21361 accaattttg tcccgagccc gtcgtgctcc aggccgttgc tcccgcggcc accgggcggg
    21421 ccggaacacg tccgcgtccc atcaggtccg ctgccggccc gccctgccag ctccgcgtgc
    21481 gccacaatcc gcgctcagcc cacacactcg atgcctgtgt agtaatgact ctctccggag
    21541 acggcgaacc tccgggggcc caccacacca cccacggggt tcgaccatgc caaaccggcc
    21601 gctcagccag aacgcgacca ccacaccagt acggcaccca cctggccaag ccccgctcga
    21661 cggacagcgg gatatcgcgc ggctgctcgg aggcgatggc cgctggcgcc tcttccggga
    21721 caacaatccc cacggcctcc ggctcgatac ctacagcgac aggtggactc tcactcgcga
    21781 gttccacgtc cacatcaacg gcaccgacgg tgaacgatgg gacatgatca ccgaaccatc
    21841 gcccgtctgc ctcgggggat gggacgccca gcgctgcgag tacgtggcgc gcaggctgcc
    21901 gaccgggcag gtgatcgcca ggggcgacac gcaatacggg gtcctggcgc gcgccgcgcg
    21961 acggtgcctt cccaatgccc ggcaccaccc accgcggggc cagtgaccac agcgccccag
    22021 cgcccttggg gcgactgctc ggcggaggcc ggggggttag tttggcgaac tccccccggc
    22081 cgcctggcat ccgacgccac acgggcccca acgaaccctt acgccggacg cgtgccgccc
    22141 atcgtacggc agcccccaac catcggccgt gaagcagacc atgagaagcg tcctcagccg
    22201 ccatccgccg accatgcggc tcgcccacca gtgcgtacgg catcatcact ccatgtccac
    22261 gcgctcccca cacggccgcg atgtcgtcaa ccgggtcgaa gcagcggcga tgctcggcat
    22321 ctccgtcagc cacctcgacc ggctctaccg cgagcgcgac agcaacggct tccccgagcg
    22381 cgccgccgac ggccgcacat ggcaccgtca ggacatcgcc aaatacgaac tgccacgcga
    22441 acaggccacg cgcagcgcac gcgacagcgt cgaccgctcc ggggacccgg acgagttggt
    22501 cgacaccgcg acagcggccc gcatcctcgg ctaccgcgac cgaagcgccc tcgccggaaa
    22561 caaccccgtg tggctacggc tgcagcagca ggtggatgac gaatcgtcga ccccatccgg
    22621 ccgcaaacgc agacggtgga agcgccgcac cgtgtgggag atcgcggaaa accgcatcgg
    22681 caagggaggc gcgacgcgaa ccggacggcc agccggcact ccccacggcc accccgaccg
    22741 ctccggcaag ccggacgaac tggtgggcaa agccgaagcc gcccgagtgc tcggctacag
    22801 caccgccaac gccctaccca gtcgcgtgct ggagcgcgcc gatgagcaga cagcaggccc
    22861 aaaggggcgc taccgccgca agtggaggcg cgaaacgctg tgggccatcc tggacgagca
    22921 gggcacaccc cccacccctg atctgctcag ctagccctcg gcgtagggct gccgccgacc
    22981 ccgaccgatc accgtacttc cgctcacgag acgcccggcc ctggcgggcc gggtaaaccg
    23041 gaagcggcct ccggccgcac tgcccaaacc ccttcaccgg tgggggccgc gacaggctag
    23101 cgacgtgctc gctccggtca agtccgggcg cggctcggaa acatcatgca caccccgcat
    23161 gatctttcct cgaaaccccg cgcccggact tgacctccac tgcgcgcgcc gcgggtcgag
    23221 tgaactcgcc ccccaccgcc aaaggaagtg gggggacgcg ccgtgtccgt acacggcagc
    23281 gtgatcggcg tagccgccgg caaaccaccg tcaagatcat cgaaatttct cgaccatcca
    23341 ggccgaatcg gatagatcca taccatcaga agaggtatag taatgattgt tcggaggggg
    23401 cggcgaaccc ccaccgcaca tcacacaaac cccaacccaa aggagacgca tggactccca
    23461 cgacgtcggc actccgccga tcgtcgaggg gtacggctgc acgacgtgcg gcgtacccct
    23521 caccgtgatc accacccagg gcggcggaag gacgttcctt catccccgca gcagcaacga
    23581 cgaccacgaa cccaacccgg tgccgctcgc acagctcgcg cacgtcgaaa tgacctgcga
    23641 tttttgctcc gcgcctcgcc cggtggcgtc gttcaccttc gcaaagctcg aaatcgccat
    23701 gacgaccgca cccgacgtca gcggcatggc gatgcacaac ctcggcggca gttgggcagc
    23761 gtgcgaggga tgcgcgcgcc tggtcgagca gcgcgacccc gaagggctga ccgctcgcgc
    23821 cgtcaaacgc gcccgccgcc gtggcctgtc ggatgacgcg cagagcttct tccgacccct
    23881 gcaccaagcc ctcttcgccg ccactcccag cacaccggca cgacaaccgc tcccctacgg
    23941 ggcgaacaac cgcagttgcc ctcccgcgca ggacgccgct cccgcccccg aggtacggtc
    24001 gctgcgcccg cagatgctgc caaaggtgcg ggaccggctc gtgcgtttct ggcgcacgtc
    24061 cggcggctcg tatctcctgc gcctgctcga cagcggcgag acgtacaaga tccccgggca
    24121 cctgttcccc ggtgccccag tcgacgcccc cgccgcgatc gttgacgccc gcaaccccga
    24181 agcactgcgc cagtacaccg ccctgatggc aaaccatgcg gaaaacggac gcgtgttctg
    24241 gatcgacccc gatttcaccg ccctcgccgc gcacgcggcg cgcgatcttc ctgacgtgcg
    24301 cgtcgagcaa gtcgagatgc cggcatccga cggcctgctc gtctggcaca cgccgattta
    24361 tcagccggtg gagccacaca ccgggctaac ggtgccaatc gtcgcagcac agtggggacc
    24421 gatccccggt ggcgtttgga tcaccttcta cacccccgca gaaaccctcc tacagggtca
    24481 gcagcccacc gagttggaat tgcaggggct gcgcgagcgc atcggctggc tcgccccagt
    24541 cagtagcggc gctggactgc gcttcggtca gccgtacgca cccaacagcg aacagacgcg
    24601 cctgatgctg tgctccctga tcgccacgtg gatcctgtcg acgcagcccg acgccgaagt
    24661 caccgaggaa ccagccgaca aggcgacgcg caaggcatac cagcgcgcca accgacccgc
    24721 gccaacggtg cggctggtac ggctgcgacg caaacagcag gcccgccagg acagccccga
    24781 cggcacgacc acgcgcgtct acacccgccg atggtgggtc gccggattct tccggcagca
    24841 gccctacggc cccggccgcg gactgcgccg ccgaacctac gtccgccctc acatcaaggg
    24901 accggccgac gccccgctca tcctgaccga tcaggttcac gtgctcggcg acgcccgcaa
    24961 gcgacaccag ccgtagagac gtcacagggg agccggcctc gccggctccc ctgttacccg
    25021 tcaatggcaa cacctcgaca aataagggcg tgatcgacgt ag
//
