LOCUS       NZ_CP031263            14813 bp    DNA     linear   CON 30-MAR-2024
DEFINITION  Micromonospora aurantiaca strain 110B(2018) chromosome, complete
            genome.
ACCESSION   NZ_CP031263
VERSION     NZ_CP031263.1
KEYWORDS    RefSeq.
SOURCE      Micromonospora aurantiaca
  ORGANISM  Micromonospora aurantiaca
            Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
            Micromonosporaceae; Micromonospora.
REFERENCE   1  (bases 1 to 7255264)
  AUTHORS   Wang,R.
  TITLE     Streptomyces kandeliansis sp. nov., an endophytic bacterium isolated
            from mangrove plant
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7255264)
  AUTHORS   Ye,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (24-JUL-2018) Ocean College, Zhejiang University, Zhedalu,
            Zhoushan, Zhejiang 316000, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 18-JUL-2018
            Assembly Method                   :: ABySS v. 1.5.2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 25.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_003351365.1-RS_2024_03_29
            Annotation Date                   :: 03/29/2024 12:17:52
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,622
            CDSs (total)                      :: 6,558
            Genes (coding)                    :: 6,457
            CDSs (with protein)               :: 6,457
            Genes (RNA)                       :: 64
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 101
            CDSs (without protein)            :: 101
            Pseudo Genes (ambiguous residues) :: 0 of 101
            Pseudo Genes (frameshifted)       :: 49 of 101
            Pseudo Genes (incomplete)         :: 65 of 101
            Pseudo Genes (internal stop)      :: 6 of 101
            Pseudo Genes (multiple problems)  :: 18 of 101
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:44:53
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2530512
            Orig. end                         :: 2545325
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031263.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Dr. Min Wu.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..14813
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAGGN"
                     /region_number="5"
                     /rules="((TIGR03104 or cds(GATase_7 and Asn_synthase)) and
                     TIGR03103 and (TIGR03106 or Peptidase_M42))"
                     /tool="antismash"
     cand_cluster    1..14813
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /kind="single"
                     /product="NAGGN"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..14813
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:9813](-)"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..9813)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((TIGR03104 or cds(GATase_7 and
                     Asn_synthase)) and TIGR03103 and (TIGR03106 or
                     Peptidase_M42))"
                     /neighbourhood="5000"
                     /product="NAGGN"
                     /protocluster_number="1"
     gene            complement(180..1226)
                     /locus_tag="DVH21_RS12500"
                     /old_locus_tag="DVH21_12500"
     CDS             complement(180..1226)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787506.1"
                     /locus_tag="DVH21_RS12500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12500"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_041798807.1"
                     /transl_table=11
                     /translation="MGDAGSVAPVRRQRARQIARLAAIGTGATVAATAATGGVLLGQAR
                     QARRTIPMAQAPPPRCDGVYGARLPGPPITMVILGDSSAAGYGVHRRRETPGSLLATGL
                     SRRLHRPVRLHRFAVVGALSSGLKPQVESALEVEPDVAVILVGGNDVTNRSPFSVAVRY
                     LVDAVRTLRAAGCEVVVGTCPDLGTIRPIQPPLRWLARRWSRQLAAAQTVGVVEAGGRA
                     VSLGDMLGPRFAAEPGRMFAWDRFHPSAEGYAIAAAALLPTVLSALGAVPERRPVLPGV
                     EGVRSLPEAAHQAARHAGTEVSGAQLRGRDRGPGGRWAQLRRRAFFGVGAVPPTGSAAD
                     SATLEGTS"
     gene            1368..1724
                     /locus_tag="DVH21_RS12505"
                     /old_locus_tag="DVH21_12505"
     CDS             1368..1724
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074683.1"
                     /locus_tag="DVH21_RS12505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12505"
                     /product="YkvA family protein"
                     /protein_id="WP_013474058.1"
                     /transl_table=11
                     /translation="MGKTLKRSAAFAALARALAAGTRGGPSLGARLAALPRMIRATTRG
                     EYDGGLRLALMAGATAYIVSPIDLLPEIPLAIFGLADDAVMVTWLAGSVLAETERFLEW
                     EARRSSVIPGHVVP"
     gene            1801..3171
                     /locus_tag="DVH21_RS12510"
                     /old_locus_tag="DVH21_12510"
     CDS             1801..3171
                     /EC_number="4.2.1.22"
                     /GO_function="GO:0004122 - cystathionine beta-synthase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018742048.1"
                     /locus_tag="DVH21_RS12510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12510"
                     /product="cystathionine beta-synthase"
                     /protein_id="WP_013474059.1"
                     /sec_met_domain="PALP (E-value: 7.1e-72, bitscore: 240.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQYYDNVVELIGNTPLVRLRNVTEGIQATVLAKVEYVNPGGSVKD
                     RIAMRMVEDAEKAGILRPGGTIVEPTSGNTGVGLALVAQLKGYRCVFVCPDKVSQDKQD
                     VLRAYGAEVVVCPTAVAPEDPRSYYNVSDRLAREIPGAWKPNQYSNPANPRSHYETTGP
                     ELWRQTEGKITHFVAGVGTGGTISGIGRYLKEASEGRVKVIGADPEGSVYSGGTGRPYL
                     VEGVGEDFWPETYDRGIADEIVEVSDKESFEMTRRLAREEGLLVGGSCGMAVVGALEVA
                     RKAGPDDVIVVLLPDGGRGYLSKIFNDKWMARYGFLDDSGTEPTVADALTGKPGGLPEL
                     VHVHPTETVRDAIDYMREYGVSQLPVLKAEPPVVTGEVAGSIAEKDLLDALFTGQAHLH
                     DTIERHMGEPLPMIGGGQPVSEAVGLLEKADAALVLVDGKPKGVLTRQDLLAHLGAR"
     gene            complement(3261..3770)
                     /locus_tag="DVH21_RS12515"
                     /old_locus_tag="DVH21_12515"
     CDS             complement(3261..3770)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787509.1"
                     /locus_tag="DVH21_RS12515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12515"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_114919474.1"
                     /transl_table=11
                     /translation="MTISLRSATEADLMAVGALHQRSRTAAYSSFLPPEALADPTPEAM
                     GRYWVERLTWEGADHRMTVAERDGRLVGFSYLGPDDEGDPATGLLNAIHLEPSERGRGT
                     GRALMVDALDAMRARGWTRAVLWVLRDNAVARGFYERGGWTATGEQRDEHIGRVLVPQL
                     RYARRL"
     gene            complement(3767..4696)
                     /locus_tag="DVH21_RS12520"
                     /old_locus_tag="DVH21_12520"
     CDS             complement(3767..4696)
                     /EC_number="3.1.26.11"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018586560.1"
                     /locus_tag="DVH21_RS12520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12520"
                     /product="ribonuclease Z"
                     /protein_id="WP_013284123.1"
                     /transl_table=11
                     /translation="MSMRELVVLGTASQAPTRQRNHNGYLLRWDDEVILFDPGEGSQRQ
                     MLHTGVTATDLTRICVTHFHGDHCLGLPGMIQRLSLDRVPRPVAVHFPAGGAEYFARLR
                     HASSFYETAELAVEPIDADGQRITLGIGTLEARRLRHPIETYGYRLVEPDGCRMLPERL
                     AAYGIAGPDVGRLLRDGHLDRDGRRVTRDEVSVTRPGQRFAFVMDTGLCDGVYALAEHA
                     DLLVIESTFLESEAALAAEVGHLTAGQAARVAAESGVRTLVLTHFSQRYADPRRFHDEA
                     REHFSGDLVIAEDLQTVQVPPRRVPSPG"
     misc_feature    4917..4932
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.95"
                     /tool="antismash"
     gene            complement(5001..6185)
                     /locus_tag="DVH21_RS12525"
                     /old_locus_tag="DVH21_12525"
     CDS             complement(5001..6185)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03106"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Peptidase_M42"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787511.1"
                     /locus_tag="DVH21_RS12525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12525"
                     /product="osmoprotectant NAGGN system M42 family peptidase"
                     /protein_id="WP_013474062.1"
                     /sec_met_domain="TIGR03106 (E-value: 4.8e-146, bitscore:
                     484.5, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_M42 (E-value: 4.1e-56, bitscore:
                     188.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARKPQPLKLDLDYLRQVLVELLEIPSPSGRTDHIQQYVGERLS
                     AIGISSTLTRRGALSACLPGPRSTGADRAVVVHTDTIGGMVKRLKENGRLEVNPIGTHS
                     ARFAEGAHVRIFTDDLDRVVTGQVLPLKASGHRYNEAVDLQGVGWELVEVRVDEPVHDE
                     AGLRALGIDAGDFVAFLPNPTITPNGYVKSRHLDDKAGVAAVLTAFKAMVDAGVTPAVT
                     AHLLVTVTEEIGHGASHGLDPDVAEIVSVDAAVVAPGQQSRETAATLAMGDGVGPFDYH
                     LTRNLASIAKEHGVDLVRDVFDYYRSDVAAAVEAGAHARVALLGFGVDATHGHERTHLD
                     GLHQLTQLLCLYLQSPLVFPEWDAEPEGDLADFPSLAVQPANEEGPREGPIGLD"
     gene            complement(6182..8020)
                     /gene="ngg"
                     /locus_tag="DVH21_RS12530"
                     /old_locus_tag="DVH21_12530"
     CDS             complement(6182..8020)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ngg"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03103"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787512.1"
                     /locus_tag="DVH21_RS12530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12530"
                     /product="N-acetylglutaminylglutamine synthetase"
                     /protein_id="WP_114919475.1"
                     /sec_met_domain="TIGR03103 (E-value: 1.5e-238, bitscore:
                     791.2, seeds: 7, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 1.8e-07, bitscore: 29.5,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 6.1e-07,
                     bitscore: 27.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTLATGTARTDRERVLGRRRELTGPGGDPVAPGTPEPRQPETA
                     SADASGVVLDCGWGRLVFGQTFDDQVHVADVLRSEAVGARDICIYLRDPHVLVSRLPDE
                     LFIDPSLTYRLPLGEKRPAATEGGEVPGLTVRPLRDAADAEAVNRIYARNGMVTAPVEV
                     LVDNAGTDRFLHLVAEDTTGEVVGTITGVDHVAVFGDPEKGASLWCLTVDFNTAPPGTG
                     QALLTALADRLDERGQAFVDLSVLAENSGAIRLYERLGFHRTGTLCVKRKNPINERLFL
                     PAMPEGYDELNPYAKIVADEAMRRGIRVEVTDPHWGELKLTTGGRTIHTRESLSELTSA
                     VAMSRCDDKRVTRRILTEAGLSVPRGRTATGEPDDVTFLDDVGPVVVKPARGEQGNGIT
                     VGVRTPEALTAAVELARRFCPDVLIEELRAGEDLRVVVIDHEVVAAAVRRPAQITGDGV
                     HDITELIERQSRRRAAATGGESRIPVDDMTREVVAEAGYRMHDVLPEGEVLAVRRTANL
                     HTGGTIHDVTAELHPAIAEACVTASRALDIPVTGLDLLVPAPDRPEHVFIEANERPGLA
                     NHEPQPTAERFVDLLFPGTRAPQRLWSPAGAAGSGA"
     gene            complement(8023..9813)
                     /locus_tag="DVH21_RS12535"
                     /old_locus_tag="DVH21_12535"
     CDS             complement(8023..9813)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     TIGR03104"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     GATase_7"
                     /gene_functions="biosynthetic (rule-based-clusters) NAGGN:
                     Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074689.1"
                     /locus_tag="DVH21_RS12535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12535"
                     /product="N-acetylglutaminylglutamine amidotransferase"
                     /protein_id="WP_013284126.1"
                     /sec_met_domain="TIGR03104 (E-value: 8.1e-285, bitscore:
                     944.1, seeds: 10, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 2.1e-40, bitscore:
                     136.1, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 3.4e-86, bitscore:
                     288.7, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCGLAGEFRRDGSRADVSAVERMAATMSDRGPDDSGVWSQGPTAL
                     GHRRLKIIDLSAASGQPIVDAAAGLTGVFNGCIYNYRELRAELQAKGHRFFSSGDSEVV
                     VKAYAEWGLDFVDHLIGMFAVAISERDTGRLVLARDRLGIKPLYLAESPGVVRFASTLP
                     ALLAGGGIDTTIDRVALAHYLSFHSIVPPPRTILAGVTKLPPATVRVYEADGSTHERVY
                     WDPAFSRAAERAGWSERDWQDALLDSLTTAVRRRMVADVPVGVLLSGGLDSSLVVALLA
                     GEGQARSGLATFSIGFDAVGGREGDEFVYSDLVAKTFGTDHHQIRVPTGDLLPPLESAV
                     AAMSEPMVSHDCVAFWLLSQEVARHVKVVQSGQGADEILGGYHWYPPLAGVDREQALET
                     YAKAFFDRDAAGLARVLNPAWLADGDPAREFVAAHLGRAGAQTAVDAGLRIDTQVMLTD
                     DPVKRVDNMTMAHGLEARVPFLDHEFVELAASCPPELKLAQGGKGVLKEIGRRVLPHEV
                     IDRPKGYFPVPGLTHLEGKLLDRVRDALTAPEARRRDLFRADYVDALLADPNAELTPLN
                     GNKLWQLGLLEMWLQSHGID"
     misc_feature    complement(9844..9858)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.52"
                     /tool="antismash"
     misc_feature    complement(9895..9908)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.24"
                     /tool="antismash"
     gene            10019..10486
                     /locus_tag="DVH21_RS12540"
                     /old_locus_tag="DVH21_12540"
     CDS             10019..10486
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018352175.1"
                     /locus_tag="DVH21_RS12540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12540"
                     /product="hypothetical protein"
                     /protein_id="WP_013474063.1"
                     /transl_table=11
                     /translation="MSMPLESVPFSELLRQPTETAERLARTRALRLRRRDAADLVLMSA
                     ERAEAEGEVVDLTARLLAGLARREPALVRETLPTVLPWMRFLPQGDAEQMTDEFIATAE
                     AAAAVGSTAAVSQLLAEWRHTAEVHADPDLHRILAAPSADDFGPVTRPTDE"
     gene            10483..10836
                     /locus_tag="DVH21_RS12545"
                     /old_locus_tag="DVH21_12545"
     CDS             10483..10836
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453701.1"
                     /locus_tag="DVH21_RS12545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12545"
                     /product="hypothetical protein"
                     /protein_id="WP_030271227.1"
                     /transl_table=11
                     /translation="MSAKRGDRAAPPPRPGGYTLRFATNDAAKGWEELCRQAAANTRGA
                     FDAIEAHPCPSPPTSRQHPLKGSLATAVHNGRALPQWQYEVTAGGRVWYLVDDQTRTCW
                     IKHAGTGHPRATD"
     gene            complement(10903..11562)
                     /gene="msrA"
                     /locus_tag="DVH21_RS12550"
                     /old_locus_tag="DVH21_12550"
     CDS             complement(10903..11562)
                     /EC_number="1.8.4.11"
                     /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide
                     reductase activity [Evidence IEA]"
                     /GO_function="GO:0033744 -
                     L-methionine:thioredoxin-disulfide S-oxidoreductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0030091 - protein repair [Evidence IEA]"
                     /codon_start=1
                     /gene="msrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007074691.1"
                     /locus_tag="DVH21_RS12550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12550"
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="WP_013474064.1"
                     /transl_table=11
                     /translation="MFLRRMKAEMISPDQALPGRPIAMPIADRHEVLPSSLKGPFPEGA
                     QVAVFGMGCFWGAERLFWTLPGVITTSAGYAGGYTTNPTYEEVCSGMTGHAEVVQVVYD
                     PSKIAYEDLLKVFWENHDPTQGMRQGNDVGTQYRSAIYTTTDEQLAAAKASRDAFAPIV
                     ERAGKGEITTEIAPLGDYYFAEDYHQQYLAPTKNPNGYCNHGPNGLSCPVGVARTA"
     gene            complement(11639..12052)
                     /locus_tag="DVH21_RS12555"
                     /old_locus_tag="DVH21_12555"
     CDS             complement(11639..12052)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013474065.1"
                     /locus_tag="DVH21_RS12555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12555"
                     /product="HIT family protein"
                     /protein_id="WP_013474065.1"
                     /transl_table=11
                     /translation="MSGCVFCGIVAGEVPAFRVTDEPDGVAFLDTRPVFKGHVLVVPRT
                     HLVTLSDLPADALPGYFRLVQRIAVAVESGLGSGGTFVAMNNRVSQSVPHLHTHVVPRT
                     KGDGLRGFFWPRTRYADDAEATEFAGRISAALA"
     gene            complement(12207..12533)
                     /locus_tag="DVH21_RS12560"
                     /old_locus_tag="DVH21_12560"
     CDS             complement(12207..12533)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018787517.1"
                     /locus_tag="DVH21_RS12560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12560"
                     /product="hypothetical protein"
                     /protein_id="WP_071096722.1"
                     /transl_table=11
                     /translation="MSTTEALPSRLHGVADRIPTCLDDLKGPEHGRVTLPIRLAWSGLT
                     EFDVDDSGQRLTLYRTLMDCGQREDIVRYVNPALLRQDWSRIRKLTAHRVIRLWESRIP
                     GLAA"
     gene            12629..13771
                     /locus_tag="DVH21_RS12565"
                     /old_locus_tag="DVH21_12565"
     CDS             12629..13771
                     /EC_number="2.5.1.48"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (47-186). E-value:
                     6.4e-09. Score: 27.3. Matches aSDomain:
                     nrpspksdomains_DVH21_RS12565_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168: O-succinylhomoserine sulfhydrylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011904831.1"
                     /locus_tag="DVH21_RS12565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="DVH21_12565"
                     /product="cystathionine gamma-synthase"
                     /protein_id="WP_013474068.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 7e-07, bitscore:
                     27.3, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.8e-08,
                     bitscore: 31.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 1.9e-05, bitscore:
                     22.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHGFETLAIHAGQDPEARTGAVIPPIYQTSTYAQDAVGAPREGY
                     EYSRSGNPTRDALQECLAALEGGPVALAFASGLAAEDTLLRTVCKPGDHVVIPDDAYGG
                     TYRLFAKVAERWGLSYTPAKVSDPDAVRAAIRPGTTRIVWVETPTNPLLGIADIAALAA
                     VAHDAGALLVVDNTFASPYLQQPIAFGADVVVHSTTKYVGGHSDVVGGALVAADRTLGE
                     ELRYHQNAMGAVNGPFDAWLTLRGIKTLGVRMDRHCDNAERVAAYLDGHAKVAQVVYPG
                     LPSHPGHEVAAKQMRRFGGMISFRAAGGEEHAVQICNRARLFVLAESLGGVESLIEHPG
                     RMTHASAAGSPLEVPGDLVRLSVGIETVDDLLADLEQALG"
     aSDomain        12770..13186
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_DVH21_RS12565_Aminotran_1_2.1"
                     /evalue="6.40E-09"
                     /label="DVH21_RS12565_Aminotran_1_2.1"
                     /locus_tag="DVH21_RS12565"
                     /protein_end="186"
                     /protein_start="47"
                     /score="27.3"
                     /tool="antismash"
                     /translation="SRSGNPTRDALQECLAALEGGPVALAFASGLAAEDTLLRTVCKPG
                     DHVVIPDDAYGGTYRLFAKVAERWGLSYTPAKVSDPDAVRAAIRPGTTRIVWVETPTNP
                     LLGIADIAALAAVAHDAGALLVVDNTFASPYLQQP"
ORIGIN
        1 attcgctcgc tgcgctcgct catgacgcca ctccgcttcg ctccgtgccg ccatgaggca
       61 ccttcgcgct gagccggctg attcgctcgc tgcgctcgct catgacgcca ctccgcttcg
      121 ctccgtgccg ccatgaggca ccttcgcgct gagccggccg attcgctcgc tgcgctcgct
      181 catgacgttc cctccagcgt tgccgagtcg gcggcgctgc cggtcggtgg caccgcgccg
      241 acgccgaaga aggcccgccg gcgaagctgc gcccaccgcc cgcccggtcc gcggtcgcga
      301 ccccggagct gggcgccgct gacctccgtg ccggcgtgcc gggccgcctg gtgggcggcc
      361 tccgggagcg accgtacgcc ttccacgccg ggcaggacag gcctgcgttc cgggaccgcg
      421 cccaacgcgg acagcacggt gggcagcaac gccgccgcgg ctatcgcgta cccctcggcg
      481 gaggggtgga accggtccca ggcgaacatc cgcccgggct cggcggcgaa ccgcggcccg
      541 agcatgtcgc cgagcgagac ggcacggccg ccggcctcga ccacgcccac cgtctgcgcg
      601 gcggcgagct ggcggctcca gcgccgggcc agccagcgca gcggcggctg gataggccgg
      661 atggtgccca ggtcggggca ggtgccgacg accacctcgc agccggccgc ccggagcgta
      721 cggaccgcgt cgaccaggta gcgcaccgct accgagaacg gtgagcggtt ggtgacgtcg
      781 ttgccaccga ccaggatcac ggccacgtcc ggctcgacct ccagggcgga ttcgacctgc
      841 ggcttcagcc ctgaggacag cgcaccgacc acggcgaacc ggtgcagccg gaccggccgg
      901 tgcaggcggc gggacagccc ggtggccagc agcgagcccg gtgtctcccg gcgcctgtgc
      961 acgccgtacc cggccgctga ggagtcgccc aggatgacca tggtgatcgg cgggccgggc
     1021 agtctcgcgc cgtacacacc gtcgcagcgc ggcggcgggg cctgcgccat cgggatggtg
     1081 cggcgggcct gccgggcctg gccgagcagc accccgccgg tggcggcggt ggccgccacc
     1141 gtggcgcccg tgccgatcgc cgcgaggcgg gcgatctgcc gggcgcgctg ccggcggacc
     1201 ggcgcgacgg aaccagcgtc ccccatgaac cgacagtatc gcgccggtac gaccactgct
     1261 gtccttgatc ggatggctgg gcggtgcccg gatcgggtac cgatgggtgc agcggacgcg
     1321 ggcttgccac cgggccgcac catggtcggg cggagagggg cgaaatcatg gggaagacgt
     1381 tgaagcgcag tgccgcgttc gcggcgctgg cccgggcgct ggcggcgggc acgcggggcg
     1441 ggccgtcgct cggggcacgg ctggcggcgc tgccgcggat gatccgcgcg accaccaggg
     1501 gcgagtacga cggtggcctg cgcctggcgc tgatggcggg ggcgacggcg tacatcgtct
     1561 ccccgatcga cctgctcccg gagatcccgc tggcgatctt cgggctggcc gacgacgcgg
     1621 tcatggtcac ctggctggcc ggcagcgtgc tcgccgagac cgagcggttc ctggagtggg
     1681 aggcacgtcg cagctccgtc atccccgggc atgtggtgcc ctgacggcac gtacgctggt
     1741 cggcgaactg acggctgacc gaccgcccca cgacggcggc gcgacgaagg gcacaacgag
     1801 gtgcagtact acgacaacgt cgtcgagctg atcggcaaca ccccgctggt acgcctgcgc
     1861 aacgtcaccg agggcatcca ggccaccgtg ctggcgaagg tggagtacgt gaacccgggc
     1921 ggctcggtca aggaccggat cgcgatgcgc atggtggagg acgccgagaa ggcgggcatc
     1981 ctgcggccgg gcggcacgat cgtggagccg accagcggca acacgggcgt cgggctggcc
     2041 ctggtggccc agctcaaggg ctaccgctgc gtcttcgtct gcccggacaa ggtcagccag
     2101 gacaagcagg acgtgctgcg cgcgtacggc gccgaggtgg tggtctgccc gaccgccgtc
     2161 gcgccggagg acccgcgctc ctactacaac gtctccgacc ggctggcccg ggagatcccc
     2221 ggcgcgtgga agcccaacca gtacagcaac ccggccaacc cgcgctcgca ctacgagacc
     2281 accggtccgg agctgtggcg gcagaccgag gggaagatca cccacttcgt cgcgggcgtc
     2341 ggcaccggcg gcaccatctc cggcatcggc cgctacctca aggaggcgtc cgagggccgc
     2401 gtcaaggtga tcggcgcgga cccggagggc tcggtctact cgggcggcac cggccggccg
     2461 tacctggtcg agggcgtcgg tgaggacttc tggccggaga cgtacgaccg ggggatcgcc
     2521 gacgagatcg tcgaggtgtc ggacaaggag tccttcgaga tgacccgccg gctggcccgc
     2581 gaggagggtc tgctggtcgg cggctcctgc ggcatggcag tggtgggcgc gctggaggtg
     2641 gcccgcaagg ccggcccgga cgacgtgatc gtggtgctgc tgccggacgg cggccggggc
     2701 tacctgtcga agatcttcaa cgacaagtgg atggcccggt acggcttcct tgacgactcg
     2761 ggcaccgagc cgaccgtcgc cgacgcgctc accggcaagc ccggtggcct gcccgagctg
     2821 gtgcacgtgc acccgaccga gacggtccgc gacgcgatcg actacatgcg cgagtacggg
     2881 gtctcccagc tcccggtgct caaggccgag ccgccggtgg tgaccggtga ggtggccggc
     2941 tcgatcgccg agaaggacct gctcgacgcg ctgttcaccg gccaggccca cctgcacgac
     3001 acgatcgagc ggcacatggg cgagccgctg ccgatgatcg gcggcggcca gccggtgagc
     3061 gaagcggtcg gactgctgga gaaggcggac gcggcgctgg tgctggtcga cggcaagccc
     3121 aagggcgtgc tgacccgcca ggacctgctg gcccacctcg gcgcccgctg accctgcggt
     3181 gtaaggaagg gccccctttt aacactcggt gttaaaaggg ggcccttcct ctaccggagg
     3241 cgttaagaag gggcccttcc ttacaagcgg cgggcgtagc ggagctgggg gacgagcacc
     3301 cggccgatgt gctcgtcccg ctgctcaccg gtggcggtcc agccgccgcg ctcgtagaac
     3361 ccccgcgcga cggcgttgtc ccgcagcacc cacagcaccg cgcgcgtcca tccccgggcc
     3421 cgcatcgcgt cgagcgcgtc caccatcagc gcccgcccgg tgccccggcc gcgctcggac
     3481 ggctccaggt ggatcgcgtt gagcagcccg gtcgccgggt cgccctcgtc gtccggcccg
     3541 aggtagctga agcccaccag ccgcccgtcc cgctcggcca ccgtcatccg gtggtcggcg
     3601 ccctcccagg tcagccgctc cacccagtaa cggcccatcg cctcgggcgt cgggtcggcc
     3661 agcgcctcgg gcggcaggaa cgacgagtac gccgccgtcc gtgaacgctg gtgcagggcg
     3721 ccgaccgcca tcaggtcggc ctcggtcgcg gaacgtaggg agatcgtcac ccgggcgacg
     3781 gtacccgccg gggcggcacc tgcaccgtct ggagatcctc ggcgatcacc agatcaccgg
     3841 agaagtgctc ccgggcctcg tcgtggaacc ggcgcgggtc ggcgtaccgc tgggagaaat
     3901 gggtgagcac gagcgtgcgt acccccgact cggccgccac ccgcgcggcc tggccggcgg
     3961 tgaggtgccc gacctcggcg gcgagcgccg cctcggactc caggaacgtc gactcgatca
     4021 ccagcaggtc ggcgtgctcg gccagcgcgt acacgccgtc gcagagtccg gtgtccatca
     4081 cgaacgcgaa ccgctgcccc ggccgggtca cgctcacctc gtcccgggtg acgcggcgtc
     4141 cgtcgcggtc caggtgcccg tcgcgcagca gccgccccac gtccggaccg gcgatgccgt
     4201 acgcggccag ccgctccgga agcatccggc agccgtccgg ctcgaccagg cggtacccgt
     4261 acgtctcgat cgggtgccgc agccggcggg cctccagcgt gccgatgccc agcgtgatcc
     4321 gctgcccgtc ggcgtcgatc ggctcgactg cgagttcggc ggtctcgtag aagctggagg
     4381 cgtggcgcag ccgggcgaag tactcggcgc cgccggccgg gaagtgcaca gccaccgggc
     4441 gcggtacgcg gtcgagcgag aggcgctgga tcatgccggg caggccgagg cagtggtcgc
     4501 cgtggaagtg ggtgacgcag atgcgggtca ggtcggtggc ggtgaccccg gtgtgcagca
     4561 tctgccgctg gctgccctcg cccggatcga agaggatcac ctcgtcgtcc cagcgcagca
     4621 ggtagccgtt gtggttgcgt tgccgggtcg gggcctggct ggccgtaccg agcaccacca
     4681 gctcacgcat ggacacggca tcctccggaa ggcaaaaagc gacccccggg gcttccgcgc
     4741 tcacgcgcgg gccggctgga ctgggccggc accccggggg tcgggtggct gtcgtggttt
     4801 cgccgcaccg ctgccacacg gtctcgacga tcgtgcatgc ccgcctcgcg gcggacgagt
     4861 tttcactgtc gaggacagcg gctagcggac agccacctca cgagtccgat tgctatacaa
     4921 gtctggacca cctcctttcc cgtgtaccgc cacgctatcc acttcccggc ggccgcggca
     4981 acggatttcg atcacaggcg tcagtccagg ccgatcgggc cctcgcgcgg gccctcttca
     5041 ttcgccggct gcactgcgag cgacgggaag tcggccaggt cgccctccgg ctcggcgtcc
     5101 cactcgggga agaccagcgg gctctggagg tagaggcaga gcagctgggt gagctggtgc
     5161 agaccgtcga ggtgggtgcg ctcgtggccg tgggtggcgt ccacgccgaa gccgagcagc
     5221 gccacccggg cgtgcgcccc ggcctcgacc gcggcggcca cgtccgagcg gtagtagtcg
     5281 aacacgtcgc ggaccaggtc gacgccgtgc tccttggcga tcgaggcgag gttgcgggtc
     5341 aggtggtagt cgaacgggcc gaccccgtcg cccatcgcca gcgtcgcggc ggtctcccgg
     5401 gactgctggc ccggcgcgac cacagccgcg tccaccgaga cgatctccgc gacgtccggg
     5461 tccagcccgt ggctcgcgcc gtgaccgatc tcctcggtga cggtgaccag caggtgcgcg
     5521 gtgaccgccg gggtgacacc ggcgtcgacc atcgccttga acgcggtcag caccgccgcc
     5581 acgcccgcct tgtcgtccag gtgccgcgac ttgacgtacc cgttcggggt gatggtcggg
     5641 ttgggcagga acgcgacgaa gtccccggcg tcgatgccga gcgcccgcag cccggcctcg
     5701 tcgtgtacgg gctcgtccac ccgcacctcg accagttccc agccgacgcc ctggaggtcg
     5761 accgcctcgt tgtagcggtg gccgctcgcc ttcaggggca gcacctggcc ggtgaccacc
     5821 cggtccaggt cgtcggtgaa gatccgcaca tgggcgccct cggcgaagcg ggcgctgtgc
     5881 gtaccgatcg ggttgacctc cagccggccg ttctccttga gccgcttcac catgccgccg
     5941 atggtgtcgg tgtgcaccac cacggcccgg tcggcgccgg tcgaccgggg gccgggcaga
     6001 caggcgctca gcgccccgcg acgggtcagc gtggagctga tcccgatcgc ggagagccgc
     6061 tcgcccacgt actgctggat gtggtcggtg cgccccgacg ggctggggat ctccagcagc
     6121 tccaccagca cctggcggag gtagtcgagg tcgagcttga gcggttgggg tttgcgtgcg
     6181 gtcatgcccc agagcctgcc gcaccggccg gcgaccagag tcgctgcggt gcccgggtac
     6241 ccgggaagag caggtcgacg aagcgctcgg cggtcggctg cggctcgtgg ttggccagtc
     6301 cgggccgctc gttcgcctcg atgaacacgt gttccggccg gtcgggggcg ggaaccagca
     6361 ggtccagccc ggtgaccggg atgtccagcg cccggctggc agtgacgcac gcctcggcga
     6421 tcgccgggtg cagctcggct gtcacgtcgt ggatcgtgcc gccggtgtgc aggttggccg
     6481 tccgccggac cgccagcacc tcgccctccg ggagcacgtc gtgcatccgg tacccggcct
     6541 ccgccaccac ctcacgggtc atgtcgtcga ccgggatgcg ggactcaccg ccggtggccg
     6601 ccgcccggcg ccggctctgc cgctcgatca gctcggtgat gtcgtgcacg ccgtcgcccg
     6661 tgatctgcgc gggccgacgc accgcggcgg cgaccacctc gtggtcgatc accacgaccc
     6721 gcaggtcctc gcccgcgcgc agctcctcga tcagcacgtc cgggcagaac cggcgggcca
     6781 gctcgacggc cgcggtgagg gcctccggcg tacgcacgcc gacggtgatg ccgttgccct
     6841 gctcgccgcg cgccggcttg accaccaccg gacccacgtc gtcgaggaac gtgacgtcgt
     6901 cgggctcacc ggtggcggta cgcccgcgcg gcaccgacag ccccgcctcg gtgaggatgc
     6961 gccgggtcac ccgcttgtcg tcgcagcggc tcatcgccac cgccgaggtc agctccgaca
     7021 gcgactcgcg ggtgtggatg gtccggccgc cggtggtcag cttcagctca ccccagtgcg
     7081 ggtcggtcac ctcgacccgg atgccgcggc gcatcgcctc gtccgcgacg atcttcgcgt
     7141 acgggttcag ctcgtcgtaa ccctcgggca tggcgggcag gaacaggcgc tcgttgatcg
     7201 ggttcttccg cttcacgcag agcgtgccgg tgcggtggaa gccgaggcgc tcgtacagcc
     7261 ggatcgcgcc cgagttctcg gccagcacgg acaggtccac gaacgcctgg ccgcgctcgt
     7321 cgagccggtc ggcgagcgcg gtgagcagcg cctgcccggt gccgggcggg gcggtgttga
     7381 agtcgactgt gaggcaccac aggctggcgc ccttctccgg gtcgccgaag accgcgacgt
     7441 ggtccacgcc ggtgatggtg ccgaccacct cacccgtggt gtcctcggcc accaggtgca
     7501 ggaaccggtc cgtgccggcg ttgtccacca gcacctcgac cggtgcggtg accatgccgt
     7561 tgcgcgcgta gatccggttc accgcctcgg cgtcggcggc gtcgcgcagc ggccggacgg
     7621 tcagcccggg gacctcgcca ccctcggtgg cggcgggtcg cttctcgccc agcggcagcc
     7681 ggtacgtcag cgacgggtcg atgaacagct cgtccggcaa ccgggacacc agcacgtgcg
     7741 ggtcgcgcag gtagatgcag atgtcccggg cgccgaccgc ctcggagcgc agcacgtcgg
     7801 ccacgtgcac ctggtcgtcg aacgtctgcc cgaacaccag ccggccccag ccgcagtcca
     7861 gcaccacgcc cgaggcgtcg gcggacgcgg tctccggctg ccgaggctcc ggcgtacccg
     7921 gtgcgaccgg gtcaccgccg gggccggtga gttcccggcg ccggcccagc acccgttccc
     7981 ggtcggtacg cgccgttccg gtggcgaggg tgtccgtcac ggtcagtcga ttccgtggct
     8041 ctggagccac atttccagga gtcccagttg ccacagcttg tttccgttca acggggtcag
     8101 ttcggcattc gggtcggcga gcagcgcgtc gacgtagtcg gcgcggaaca ggtcgcgacg
     8161 gcgcgcctcg ggcgcggtca gcgcgtcgcg tacccggtcg aggagcttgc cctccaggtg
     8221 ggtgagtccg ggcaccggga agtaaccctt gggtcggtcg atgacctcgt gcggcaggac
     8281 ccggcgcccg atctccttga gtacgccctt gccgccctgg gccagcttca gctccggcgg
     8341 gcagctcgcg gccagctcga cgaactcgtg gtcgaggaac ggcacccggg cctccagccc
     8401 gtgcgccatg gtcatgttgt cgacccgctt caccgggtcg tcggtcagca tgacctgggt
     8461 gtcgatccgc aggcccgcgt cgacggcggt ctgcgccccc gcgcggccca ggtgcgcggc
     8521 cacgaactcc cgcgccgggt cgccgtcggc cagccacgcc gggttgagca cccgggccag
     8581 tccggccgcg tcgcggtcga agaacgcctt cgcgtacgtc tcgagcgcct gctcccggtc
     8641 caccccggcg agcggcgggt accagtggta gccacccagg atctcgtccg cgccctggcc
     8701 cgactgcacc accttgacgt gccgcgcgac ctcctggctg agcagccaga acgcgacgca
     8761 gtcgtggctg accatgggtt cgctcatggc cgcgacggcg gattccagcg gcggcagcag
     8821 gtcaccggtg ggcacccgga tctggtggtg gtcggtgccg aacgtcttcg cgaccaggtc
     8881 ggagtagacg aactcgtcgc cctcccggcc gccgaccgcg tcgaagccga tggagaacgt
     8941 ggccaggccg gaccgggcct gcccctcgcc ggcgagcagc gcgacgacca ggctggagtc
     9001 gaggccgccg gagagcagca cgcccaccgg cacgtcggcc accatgcggc ggcgtacggc
     9061 tgtggtcagc gagtcgagca gcgcgtcctg ccagtcccgc tcggaccagc cggcccgctc
     9121 ggcggcgcgg ctgaacgccg gatcccagta cacccgctcg tgggtggagc cgtccgcctc
     9181 gtacacccgg accgtggccg gcggcagctt ggtgacgccg gccaggatcg tgcgcggcgg
     9241 cggcacgatg ctgtggaagc tcaggtagtg ggcgagcgcc acccggtcga tggtggtgtc
     9301 gatgccgcca ccggcgagca gcgccggcag ggtcgaggcg aaccgcacca cgccggggct
     9361 ctcggccagg tagagcggct tgatgccgag gcggtcccgg gccagcacca ggcggccggt
     9421 gtcgcgctcg ctgatcgcca ccgcgaacat gccgatcagg tggtcgacga agtcgagacc
     9481 ccactcggcg tacgccttga ccacgacctc gctgtcgccg gacgagaaga accggtggcc
     9541 cttggcctgc agctcggcgc gcagctctcg atagttgtag atgcagccgt tgaagacacc
     9601 ggtgagcccg gcggcggcgt ccacgatggg ttggccgctc gccgcggaca ggtcgatgat
     9661 cttcaggcgc cggtgtccca gcgcggtcgg gccctgcgac cagacgccgc tgtcgtcggg
     9721 ccctcggtca ctcatcgtgg ccgccatccg ctccacggcc gatacgtcgg cgcgtgaacc
     9781 gtcacggcgg aactctcccg caagtccgca catacgagcc aatgctgcca gagcttgttg
     9841 cagttcgcct gttgagacga tgacgaacgt gtgacagctt gctacgatgc gccgtcacgc
     9901 agggtggtca cctgtcacgc cttcggttcc tgcctcgctc cacccgatgt cgggattcgg
     9961 ctcccgcgag ggtgtgagga atgccgcagc gcgctacttc tgaagtagtg ttgatgtcat
    10021 gtcgatgccc ttggagtccg tgccgttctc cgagttgctg cgccagccga cggaaaccgc
    10081 ggagcggctg gctcgtactc gggcactgcg gctacgtcgc cgcgacgccg ccgacctggt
    10141 gctgatgtcc gccgaacggg cagaggccga gggggaggtg gtcgatttga ccgcgcggct
    10201 gctggccggc ctggcgcggc gagagccggc cctggtccgc gagacgcttc cgaccgtgct
    10261 gccctggatg cggttcctgc cgcaggggga cgccgagcag atgaccgacg agttcatcgc
    10321 cacggccgag gccgcagcgg ccgtcggcag caccgcggcg gtgtcccagc tgctcgcgga
    10381 atggcggcac accgccgagg ttcacgccga tcccgatctg catcggatcc tggccgcgcc
    10441 cagcgccgac gacttcgggc cggtcacgcg cccgaccgac gagtgagcgc gaagcgcggc
    10501 gaccgcgccg ccccgccacc ccggccaggt gggtacaccc tgcggttcgc caccaatgac
    10561 gcggccaagg gctgggagga gctgtgccgg caggctgcgg ccaacactcg cggcgcgttc
    10621 gacgcgatcg aggcgcaccc ctgcccgtcc ccgccgacca gccgccagca ccccctcaag
    10681 ggttccctcg ccactgcggt gcacaacggt agggccctgc cgcagtggca gtacgaggtc
    10741 accgccggcg gccgcgtctg gtacctggtc gacgaccaga cccggacctg ctggatcaag
    10801 cacgccggca ccggccatcc ccgagccacc gattgaccgc agtgcgttcg ggccctcgtc
    10861 cctggaggac gagggcccga gtggggcagt gctcgggtct ggctacgcgg tgcgggccac
    10921 gccgaccggg cagctcagcc cgttcggtcc gtggttgcag tagccgttcg ggttcttcgt
    10981 cggagccagg tactgctggt ggtagtcctc ggcgaagtag tagtcgccga gcggcgcgat
    11041 ctcggtggtg atctcaccct tgccggcccg ctccacgatc ggcgcgaacg cgtcccgcga
    11101 cgccttggcg gcggcgagct gctcgtcggt cgtggtgtag atcgccgagc ggtactgggt
    11161 gcccacgtcg ttgccctggc gcatgccctg ggtcgggtcg tggttctccc agaacacctt
    11221 gagcaggtcc tcgtaggcga tcttcgacgg gtcgtagacc acctggacca cctcggcgtg
    11281 cccggtcatg cccgagcaga cctcctcgta cgtcgggttg gtggtgtacc cgcccgcgta
    11341 accggccgac gtggtgatca cgccggggag ggtccagaac agccgctcgg cgccccagaa
    11401 gcagcccatg ccgaagacgg cgacctgcgc gccctcgggg aacgggccct tcagcgagga
    11461 cggcagcacc tcgtgccggt cggcgatcgg catcgcgatc gggcggcccg gcagggcctg
    11521 gtcaggagag atcatttcgg ccttcatgcg gcggaggaac acggtgggac tcctctcttg
    11581 gctttcccag cgtgtgcaac atcgtcggcc ccgggttcct tacccgccca cgtcggcgtc
    11641 aggccagcgc cgccgagatc cgcccggcga actccgtcgc ctcggcgtcg tcggcgtacc
    11701 gggtgcgcgg ccagaagaag ccgcgcagcc cgtcgccctt ggtccggggc accacgtggg
    11761 tgtgcaggtg cggtacggac tgggacaccc ggttgttcat cgccacgaac gtcccaccgg
    11821 agcccagacc ggactccacg gccacggcga tgcgctgcac cagccggaag tagccgggca
    11881 gcgcgtcggc gggcaggtcg gacagggtga ccaggtgggt gcggggcacc accagcacgt
    11941 ggcccttgaa caccggccgg gtgtcgagga acgcgacgcc gtccggctcg tcggtcaccc
    12001 ggaaggccgg cacctcgccc gccacgatcc cgcagaacac acacccgctc acgagctcac
    12061 cctgggcccc acccggccac cccacctccg ggcgagcgtg atcatgaggt tggcggcgac
    12121 aaatcggacc ggcggcaccg tcaacctcat gatcggcgcg gcgcggaatc cgacgcgcag
    12181 caagcgcgtg tgcaactcgt ccacggctag gccgccaggc ccgggatcct gctctcccag
    12241 aggcggatca cccggtgtgc ggtcagcttg cggatgcggg accagtcctg ccggagaagc
    12301 gccggattca cgtaccggac gatgtcctcg cgctgcccgc agtccatcag cgtgcggtag
    12361 agcgtgagcc gctgcccgct gtcgtcgacg tcgaactcgg tgagaccgga ccacgcgagg
    12421 cggatcggca gcgtgacccg gccgtgctcg ggccccttga ggtcgtccag gcacgtgggg
    12481 atccggtcgg cgacgccgtg caggcgggag gggagcgcct cggtcgtact caccggacca
    12541 gtatggccga ccaccccgac accttcgcgg ttgtgactcg cgccgggttg acgagagcgg
    12601 gagcgggcgg ggggctaacg tctgcggcat gagccacggc ttcgagacac tcgccatcca
    12661 cgccggtcag gacccggagg cccgcaccgg tgcggtgatc ccgccgatct accagaccag
    12721 cacgtacgcc caggacgccg tcggcgcgcc ccgcgagggc tacgagtaca gccgctccgg
    12781 taaccccacc cgcgacgcgc tccaggagtg cctcgccgcg ctggagggcg gcccggtggc
    12841 gctcgccttc gccagcggcc tggccgccga ggacacgctg ctgcggaccg tctgcaagcc
    12901 gggcgaccat gtggtgatcc cggacgacgc gtacggcggc acgtaccggc tgttcgccaa
    12961 ggtggccgag cgctggggcc tgtcgtacac cccggcgaag gtctccgacc cggacgccgt
    13021 tcgtgccgcg atccgcccgg gcaccaccag gatcgtctgg gtggagacgc cgaccaaccc
    13081 gctgctcggc atcgccgaca tcgccgcgct cgccgcggtg gcgcacgacg ccggcgcgtt
    13141 gctggtggtc gacaacacgt tcgcctcgcc gtacctccag cagccgatcg cgttcggcgc
    13201 ggacgtggtg gtgcactcca ccaccaagta cgtcggcggg cactccgacg tggtcggcgg
    13261 cgcgctcgtc gcggcggacc gcacgctcgg cgaggagctg cgctaccacc agaacgcgat
    13321 gggcgcggtc aacgggccgt tcgacgcctg gctcaccctg cgcggcatca agaccctcgg
    13381 ggtacggatg gaccggcact gcgacaacgc cgagcgggtc gcggcctacc tggacggaca
    13441 cgccaaggtc gcccaggtcg tctacccggg cctgccctcg caccccggcc acgaggtggc
    13501 cgccaagcag atgcgccggt tcggcggcat gatctcgttc cgcgcggcgg gcggcgagga
    13561 gcacgccgtc cagatctgca accgggcccg gttgttcgtg ctcgccgagt cgctcggcgg
    13621 cgtcgagtcc ctgatcgagc acccgggccg gatgacacac gcaagcgctg cgggctcgcc
    13681 gcttgaagtt cccggcgatc tcgtgcgact gtctgtcggc atcgagacgg tcgacgacct
    13741 gctcgccgat ctggagcagg ccctgggctg accgctggtt ggggagggtg gcagtgccgg
    13801 acatcttgcc gacgacctgg gtcgggacga ccgcgaaaca gatcgcccgg gcggtacgcc
    13861 gtggcgacgt ctccgccacc caggtcgtcg ccgaccacct ggaccacgtc gcccgggtcg
    13921 acgccgagct gggcgcgttc cgcacggtac gcggcggcga ggcgatcacc gaggcggaga
    13981 aggtcgacga gcaggaggaa ctggcgaacc tgccgctcgc cggggtgccg gtggcggtca
    14041 aggagaacac gccggtggcc ggcctgccca cctggaacgg gtcggccgcg atgcgtaccg
    14101 aggtggcgga ggcagaccac gaggtggtcc ggcggctgcg cggcgcgggc gctgtcatcc
    14161 tcggggtcac ccggatgccg gagctgggcc tgtgggccct caccgacgac gacaccgctg
    14221 tgacccgcaa cccgtgggat ccggctcgta cccccggcgg ctcgtccggc ggcgcggccg
    14281 ccgcggtggc cgccgggctg gtgccgatgg cccacggcaa cgacggtctc gggtcgatcc
    14341 gcatcccggc ggcctgctgc ggcctggtcg ggctcaagcc cggccggggc gtggtgccct
    14401 gccagctcgg cgcggacgac tggttcggcc tcaccgagca cggcatgctg accagcaccg
    14461 tcgccgacgc ggtggtcggc ttctcggtgc tggccggccg ccggccggac aagctggtcc
    14521 cgccggagcg gctgcgggtg ggcgtctcgc tgcgctcgcc ggtacgcggc gtctcgccgg
    14581 acgcgccgaa ccgggacgcg gtcgccgccg ccggccggct gctggccgcc gccggtcacg
    14641 acaccgtgcc cgccgacccg gtctacccga cccggctcgg cctccagggc atcgccacct
    14701 ggttcgcggc ggccgccgcc gacgtgcgcg ccgccggggt ggcgccgcgt caactccagc
    14761 ggcgcagccg ccggcacgtc aggctcggcg agtgggcgca gcgccggggg tac
//
